410 results about "Benzaldehyde" patented technology

The invention discloses a high-flame-retardant bio-based aerogel material and a preparation method thereof, and belongs to the technical field of flame-retardant bio-based aerogel. The high-flame-retardant bio-based aerogel material prepared by the preparation method disclosed by the invention is prepared from the following raw material components in parts by mass: 10 parts of a bio-based flame-retardant filler with a porous structure, 40 to 50 parts of a hydrophobic siloxane monomer, 12.4 to 12.6 parts of an ammonium phytate solution, 6.2 to 6.3 parts of guanosine, 31.1 to 31.4 parts of cellulose nanofibers and 0.01 to 0.02 part of benzaldehyde-polyethylene glycol-silane, the preparation method comprises the following steps: firstly, carrying out hydrolytic polycondensation on a bio-based flame-retardant filler with a porous structure and a hydrophobic siloxane monomer to form a siloxane polymer network with the bio-based flame-retardant filler as a branching center; then adding cellulose nanofibers, guanosine and an ammonium phytate solution, and performing freeze casting-freeze drying-heating post-treatment to obtain the composite material. Wherein the bio-based flame-retardant filler is obtained by compounding a porous cuttlefish ink carbon quantum dot composite material with phytic acid siloxane and trimethoxy (3-(4-nitrophenoxy) propyl) silane.

The invention discloses a preparation method of a low-chlorine composite environment-friendly coal transportation anti-freezing agent, and belongs to the technical field of anti-freezing solutions. The anti-freezing solution is used for solving the technical problems of complex components and poor anti-freezing and metal corrosion resistance of the anti-freezing solution for coal transportation in the prior art. The preparation method of the low-chlorine composite environment-friendly coal transportation anti-freezing agent comprises the following step: uniformly mixing the compound pour point depressant, the modified corrosion inhibitor, the thickening stabilizer and the industrial water to prepare the low-chlorine composite environment-friendly coal transportation anti-freezing agent. The compound pour point depressant comprises an organic pour point depressant and an inorganic pour point depressant; the organic pour point depressant is obtained by reacting unsaturated azole, sodium methallyl sulfonate and fumaric acid; the unsaturated nitrogen is obtained by reaction of an intermediate B and benzaldehyde, and the intermediate B is obtained by reaction of triazole and ethyl chloroacetate; the modified corrosion inhibitor is obtained by carrying out a reaction on potassium thiocyanate, benzoyl chloride and chitosan vanillin Schiff base. The anti-freezing solution prepared by the invention has the advantages of moderate fluidity, good metal corrosion resistance and good anti-freezing performance.

The invention provides a preparation method of an omariglitazone intermediate, which comprises the following steps: by taking p-halogenated benzaldehyde as a raw material, carrying out aldol condensation reaction, hydrolysis, decarboxylation, reduction, ring closing and the like to obtain an intermediate as shown in a formula 9, carrying out catalytic reaction, reduction reaction, ring closing and the like to obtain an intermediate as shown in a formula 13, and finally hydrolyzing to obtain a target product omariglitazone intermediate A. According to the invention, links of precious metal use and chiral resolution (key steps influencing cost and yield) in the prior art are avoided, and a method for synthesizing a single configuration through a chemical method is adopted, so that the yield is greatly improved, and the production cost is greatly reduced; meanwhile, a synthesis route is broken through, a target product is synthesized through cheap initial materials, and post-treatment is simpler and more controllable.

The invention relates to the technical field of organic synthesis, in particular to 4-chloro-1-methyl-6H-heterochromene [3, 4-c] pyridine as well as a synthesis method and application of the 4-chloro-1-methyl-6H-heterochromene [3, 4-c] pyridine. The synthesis method comprises the following steps: (1) synthesizing 2-chloro-3-fluoro-4-iodine-5-methylpyridine from 2-chloro-3-fluoro-5-methylpyridine and an iodine elementary substance to obtain 2-chloro-3-fluoro-4-iodine-5-methylpyridine; (2) synthesizing 2-(2-chloro-3-fluoro-5-methylpyridine-4-yl) benzaldehyde from the 2-chloro-3-fluoro-4-iodo-5-methylpyridine, the 1, 1-bis (diphenylphosphine) ferrocene palladium dichloride, the tripotassium phosphate and the (2-formyl phenyl) boric acid, and further synthesizing the 2-(2-chloro-3-fluoro-5-methylpyridine-4-yl) benzaldehyde from the 2-chloro-3-fluoro-4-iodo-5-methylpyridine and the 1, 1-bis (diphenylphosphine) ferrocene palladium dichloride. And (3) synthesizing the 4-chloro-1-methyl-6H-heterochromene [3, 4-c] pyridine by using the 2-(2-chloro-3-fluoro-5-methylpyridine-4-yl) benzaldehyde and sodium tert-butoxide. The 4-chloro-1-methyl-6H-heterochromene [3, 4-c] pyridine compound constructed by the invention can be used for detecting the content of pesticide residue glyphosate.

The invention relates to the technical field of roadbed materials, and provides a Bayer process red mud roadbed material and a preparation method thereof.The Bayer process red mud roadbed material is prepared from, by weight, 100 parts of Bayer process filter pressing red mud, 1-30 parts of modified fly ash, 50-150 parts of a soil material, 2-10 parts of an accelerant and 0.01-0.8 part of a dispersing agent; wherein the modified fly ash is prepared from the following raw materials: fly ash, a silane coupling agent and 4-(2-hydroxyethoxy) benzaldehyde, and through the technical scheme, the problem that the Bayer process red mud roadbed material in the prior art is low in impermeability and mechanical property is solved.

The invention discloses a non-woven fabric made of Juncao fibers, and belongs to the technical field of textiles. The non-woven fabric made of the Juncao fibers is obtained by opening and mixing modified Juncao regenerated cellulose fibers, carding to form a net and needling and reinforcing; the modified pennisetum sinese regenerated cellulose fiber is prepared by the following steps: dipping dried pennisetum sinese pulp, squeezing, carrying out graft copolymerization on the squeezed dried pennisetum sinese pulp, 2-acrylamide-2-methylpropanesulfonic acid and benzaldehyde PEG acrylamide under the catalysis of ceric ammonium nitrate, dissolving, then adding chamomile essential oil microcapsules, reacting, and spinning. The chamomile essential oil microcapsule is prepared by the following steps: dispersing chamomile essential oil into a continuous phase containing an allyl monomer by an SPG membrane emulsification method to form a microemulsion, and preparing the chamomile essential oil microcapsule by combining an interfacial polymerization method; wherein the allyl monomer is prepared from methacrylic acid, methyl methacrylate, pentaerythritol tetraacrylate and N-(4-acetylphenyl) prop-2-acrylamide.

The invention discloses a triarylmethane type I photosensitive dye as well as a synthesis method and application thereof. The structure of the dye is shown as a general formula I; intramolecular charge separation is optimized by regulating substituent groups, and the generation efficiency of superoxide anions and hydroxyl radicals is remarkably improved. According to the synthesis method, 4-diphenylaminobenzaldehyde or 4-vinyl benzaldehyde is used as a raw material, efficient preparation is achieved through the steps of condensation, oxidation and the like, the raw material is easy to obtain, and operation is easy and convenient. The dye has strong absorption at the wavelength of 600-630 nm, is suitable for red light triggered photodynamic therapy (PDT), especially keeps high reactive oxygen yield under the hypoxic condition, and breaks through the oxygen dependence limitation of traditional PDT. Experiments show that the dye can induce ferroptosis of tumor cells, has the functions of fluorescence imaging and treatment, and has wide application prospects in the fields of antitumor drugs, in-vivo fluorescence labeling, photoresponsive functional preparations and the like.

To provide a fine granulated agent replenishing liquid for a plating liquid, with the replenishing liquid being excellent in the initial stability and safety, and the replenished plating liquid being excellent in the aging stability, without damaging the appearance of a plating film when replenished for a long period of time nor dissolving an organic resist film present on a material to be plated.SOLUTION: A fine granulated agent replenishing liquid for a plating liquid, replenishing a fine granulated agent to a tin-based plating solution including one or two or more kinds of compounds selected from the group consisting of benzaldehyde, 1-naphthaldehyde, 1-naphthoic acid, 1-acetonaphthone, DL-1-(1-naphthyl)ethylamine, and benzylidene acetone, includes a phenyl glycol-based surfactant, the fine granulated agent and water, with a content of the fine granulated agent therein being in a range of 0.1 g / L or more and 10.0 g / L or less, a content of the phenyl glycol-based surfactant therein being in a range of 5 g / L more and 50 g / L or less, and a content of alcohol being less than 1 mass%.SELECTED DRAWING: None

The invention discloses long-acting high-dynamic hydrazone bond hydrogel as well as a preparation method and application thereof, and particularly relates to the technical field of biomedical materials. The preparation method comprises the following steps: taking 1-adamantane acetic acid and adipic dihydrazide modified sodium hyaluronate and benzaldehyde-terminated eight-arm polyethylene glycol as carrier raw materials; the hydrazone bond hydrogel with relatively high stability is prepared through a coupling reaction of an aldehyde group of benzaldehyde-terminated eight-arm polyethylene glycol and a hydrazide group of 1-adamantane acetic acid and adipic dihydrazide modified sodium hyaluronate. The beta-cyclodextrin modified m-phenylenediamine catalyst is dynamically combined into the carrier through reversible host-guest complexation between beta-cyclodextrin and 1-adamantane acetic acid, so that the long-acting high-dynamic hydrazone bond hydrogel is obtained, and the requirement of three-dimensional culture of stem cells on mechanical properties can be met; and network dynamics can be maintained for a long time, so that stem cell spreading is supported, mechanical signal transduction is activated, osteogenesis-related gene expression is promoted, and stem cell osteogenesis differentiation capability is enhanced.

This invention belongs to the field of crop cultivation technology, specifically relating to a rice nano-flavor enhancer and its application in rice cultivation. The rice nano-flavor enhancer of this invention is prepared from raw materials such as sodium octenyl succinate starch, sodium ascorbate, and sodium selenite. The prepared octenyl succinate starch-nano-selenium has advantages such as small nanoparticle size and system stability. This flavor enhancer can not only significantly improve the overall aroma of fragrant rice, but also enhance the aroma of non-fragrant rice. Specifically, it can significantly increase the content of volatile aroma compounds such as 2-acetyl-1-pyrroline (2-AP) in fragrant rice grains, and significantly increase the content of volatile aroma compounds such as vanillin, benzaldehyde, and geranylacetone in non-fragrant rice grains. Unlike traditional rice flavor enhancers, the rice nano-flavor enhancer of this invention has better applicability and a wider range of applications, helping to meet the growing market demand for high-quality rice.

This invention relates to iron single-atom composite catalysts with a double-layered carbon dot core-carbon-nitrogen shell structure and their applications. The catalyst preparation method is as follows: carbon source, nitrogen source, and iron metal salt are dispersed in a mixed solution of solvent and coordinating agent and stirred evenly, followed by hydrothermal reaction; after the reaction, the supernatant is filtered and dialyzed, and the dialysate is freeze-dried to obtain Fe. SA / CDs material; add zinc nitrate hexahydrate and iron metal salt to deionized water, add Fe SA / CDs aqueous solution, then add the solution of 2-methylimidazole completely dissolved in deionized water, ultrasonically stir, and after the reaction, obtain Fe. SA / CDs / Fe@ZIF-8 precursor; the precursor was subjected to Joule heat treatment and cooled to room temperature to obtain an iron single-atom composite catalyst with a bilayer carbon dot core-carbon-nitrogen shell structure. This invention effectively improves the catalytic activity and stability of the catalyst in the benzaldehyde oxidative nitrification reaction.

The invention discloses a high performance liquid chromatography analysis method for trace impurity content in an organic amine catalyst, and relates to the field of organic catalyst content analysis. Comprising the following steps: pretreating an organic amine catalyst sample, preparing a urea standard solution, performing HPLC (High Performance Liquid Chromatography) analysis and performing quantitative analysis by an external standard method, namely performing derivatization reaction on urea and benzaldehyde under an acidic condition, and successfully converting urea without ultraviolet absorption into dibenzylidene urea (DBU) with strong ultraviolet absorption, the technical blank of direct detection of urea is effectively filled, and the method is adaptive to a conventional ultraviolet / visible light detector to realize accurate detection. And the method has relatively high practical popularization and application values. The method has the advantages of being good in separation effect, high in sensitivity, easy and convenient to operate, high in reproducibility and the like, and can be widely applied to qualitative and quantitative analysis of various trace impurities in the organic amine catalyst.

The invention belongs to the technical field of synthesis of organic compounds, and particularly relates to a synthesis method of hydroxyl-substituted benzaldehyde, which comprises the following steps: in an organic solvent, carrying out catalytic oxidation reaction on a reaction system containing methyl-substituted phenol, an alumina-supported cobalt-copper-rare earth metal oxide catalyst and oxygen-containing gas, the hydroxyl-substituted benzaldehyde is obtained; the catalyst is cheap, easy to obtain and recyclable, and a large amount of alkali and acid are not used in the reaction process, so that the production cost can be more effectively reduced. And secondly, the catalytic oxidation reaction based on the oxidant and the catalyst is mild in reaction condition, good in reaction selectivity and free of additional pollution waste, a target product with relatively high purity and yield can be obtained through simple post-treatment after the reaction, and the green and environment-friendly properties are good. In a word, based on the synthesis method, the hydroxyl-substituted benzaldehyde is synthesized more economically, more environmentally friendly and more efficiently.

The invention discloses a process method for co-production of caprolactone and 2, 4-dimethyl benzoic acid. According to the method, cyclohexanone is taken as a raw material, oxygen is introduced as an oxidant, 2, 4-dimethyl benzaldehyde is added as a pro-oxidant, and caprolactone and 2, 4-dimethyl benzoic acid are generated through oxidation reaction. According to the technological method, oxygen and 2, 4-dimethyl benzaldehyde are used as a co-oxidation system, in the presence of the carbon framework material loaded Ti-based catalyst, cyclohexanone can be subjected to oxidation reaction under mild conditions to generate caprolactone, the reaction is safe and efficient, the selectivity of the product caprolactone and the co-product 2, 4-dimethyl benzoic acid is high, the raw material conversion rate is high, and the method is suitable for industrial production. The product yield can be obviously improved, and the economic applicability is good.

The application relates to the technical field of organic synthesis, and discloses a synthesis method of a benzoyl modified nucleoside, which comprises the following steps: dissolving or suspending a substrate in a solvent, adding N-chlorosuccinimide, reacting at a certain temperature, generating a corresponding N-chloroamine intermediate, then adding a certain equivalent of benzaldehyde, and generating a final product under the joint action of an oxidant and a catalyst. According to the method, the hydroxyl group on the sugar ring does not need to be protected, and is directly reacted with the amino group on the base, so that the side reaction is less, the obtained product is high in purity, and the yield is high.

The invention discloses a double-response controlled-release hydrogel for promoting wound healing of astaxanthin and an amino small molecule drug as well as a preparation method and application of the hydrogel, and belongs to the field of biomedical materials. The material is composed of a drug-loaded nano-micelle and a self-healing hydrogel network. Hydrophilic modification of astaxanthin and dynamic coupling of the astaxanthin and an amino small molecule drug are achieved through an astaxanthin-polyethylene glycol-benzaldehyde intermediate, and the drug-loaded nano-micelle has the pH response drug release capacity; the hydrogel network is formed by crosslinking phenylboronic acid modified carboxymethyl chitosan and dopamine through dynamic phenylboronic acid ester bonds, and has ROS responsiveness and self-healing characteristics; the multifunctional intelligent wound dressing can intelligently respond to high ROS and acidic pH microenvironment of chronic wounds, controllably release astaxanthin and amino-containing small molecule drugs, synergistically remove ROS, improve cell oxidative stress, inhibit inflammation, promote blood vessel and tissue regeneration and accelerate chronic wound healing, is excellent in self-healing performance and biocompatibility, and is an ideal multifunctional intelligent wound dressing.

The application discloses preparation of carbazolyl 3,5-dicyanopyridine derivatives, room temperature phosphor and anti-counterfeiting performance thereof. The preparation method comprises the following steps: adding ortho-, meta- or para-carbazolyl benzaldehyde and malononitrile into a reaction bottle, stirring and reacting under room temperature conditions with sodium hydroxide as a catalyst and anhydrous methanol as a solvent, and obtaining ortho-, meta- or para-carbazolyl 3,5-dicyanopyridine by separating and purifying the reaction crude product. Crystals of the three compounds are obtained by a solvent diffusion method with dichloromethane-petroleum ether as a solvent, and the crystal state room temperature phosphor material is obtained. The crystals are doped with urea / triphenylphosphine at a weight ratio of 1:100, the doped crystals are uniformly ground and mixed, and then heated to be molten, so that the host-guest doped phosphor material is obtained, and the novel material is used in the field of anti-counterfeiting patterns.

The invention relates to the field of optical fiber ribbons, and discloses a high-fiber-density windable optical fiber ribbon and a preparation method thereof.The high-fiber-density windable optical fiber ribbon comprises a plurality of optical fibers arranged side by side and a photocuring product of a bonding resin composition, the bonding resin composition comprises modified epoxy acrylate, a photoinitiator, a reactive diluent and a modified multi-walled carbon nanotube; the modified epoxy acrylate is prepared by polymerizing a hydroxyl-terminated intermediate prepared by reaction of 4-hydroxy-3-trifluoromethyl benzaldehyde and 4-aminophenol with a silicon-containing epoxy group intermediate to prepare hyperbranched epoxy resin, and introducing acrylic acid for reaction; the silicon-containing epoxy group intermediate is prepared by reacting phenyl tri (dimethyl siloxane) silane with allyl glycidyl ether; and the modified multi-walled carbon nanotubes are prepared by carrying out chemical silver plating on the multi-walled carbon nanotubes by adopting a silver ammonia method. The optical fiber ribbon prepared by the invention has good mechanical properties, high-temperature and high-humidity resistance, antistatic property and flame retardance.

The invention relates to the technical field of organic synthesis, in particular to the field of IPC C07D239, and more particularly relates to a synthesis method of a phenyl isoxazoline compound. Comprising the following steps: step 1, using a benzaldehyde compound as an initial raw material, and reacting with hydroxylamine hydrochloride to generate a benzaldoxime compound; 2, carrying out a chlorination reaction on the benzaldoxime compound generated in the step 1 and liquid chlorine through a microchannel reactor to generate a chlorinated benzaldoxime compound; and 3, carrying out ring closing on the chlorobenzaldoxime compound generated in the step 2 and an alkene compound to obtain the phenyl isoxazoline compound. A metal catalyst is not used in the preparation method, so that the solid waste treatment cost is reduced; in the step 2, a continuous flow reaction technology of a microchannel reactor is adopted, the reaction time is shortened, compared with a kettle type intermittent process, the productivity is greatly improved, and the reaction safety is higher.

The application discloses a low-oxygen and pH dual-response nano-carrier, a drug-loaded nanoparticle and application thereof, and belongs to the technical field of biological medicines. The nano-carrier with moderate particle size and low-oxygen and pH dual-response is obtained by using the reaction of aldehyde benzoic acid, nonaethylene glycol and azo-p-phenetidine, the nano-carrier is specifically targeted to a tumor site, and then specifically releases drugs, thereby reducing toxic side effects; meanwhile, after the nano-carrier responds, benzaldehyde groups are released, the benzaldehyde groups are covalently connected with proteins on a lysosome membrane, the structure and activity of the proteins are changed, the lysosome membrane is broken after the proteins are denatured, the permeability of the lysosome membrane is increased, the nano-carrier cannot be discharged to the extracellular, the drug concentration in cells is greatly improved, and the drug bioavailability of the nano-carrier is significantly improved; in addition, the drug loading capacity of the nano-carrier is high, and therefore, the nano-carrier has a good application prospect.

The application discloses a kind of photoresponsive self-repair antibacterial nylon materials and preparation method thereof.The material is modified nylon 6 polymer, aromatic Schiff base dynamic imine bond generated by condensation reaction of carboxyl benzaldehyde and p-phenylenediamine is embedded in its molecular main chain, which gives the material the ability of light-triggered self-repair without external heat source, and unexpectedly improves the mechanical properties and thermal stability of the material, the molecular chain end is bonded with antibacterial organic acid through amide bond, and the antibacterial organic acid is 2-methyl-4-(trifluoromethyl) thiazole-5-carboxylic acid.The preparation method adopts one-pot two-stage polymerization, after pressure opening ring prepolymerization, pressure relief vacuum is carried out to carry out deep condensation and end-capping, and the product is obtained by extrusion granulation and drying.The material can realize room temperature self-repair under natural light, and the antibacterial component is non-dissolution fixed.The application process is simple, the performance is adjustable, and can be used in the field of intelligent packaging, repairable antibacterial coating and biomedical materials.

The invention discloses an asphalt-based hydrophobic oil-absorbing sponge as well as a preparation method and application thereof. The asphalt-based hydrophobic oil-absorbing sponge is obtained by adsorbing cross-linked asphalt resin by a sponge and then curing, the cross-linked asphalt resin is formed by cross-linking asphalt and benzaldehyde under the catalysis of strong protonic acid. The asphalt-based hydrophobic oil absorption sponge has good oil absorption efficiency, and the oil absorption amount exceeds 40 times of the self weight. In addition, about 40 times of oil absorption efficiency can still be maintained after 10 times of circulation, which indicates that the crosslinked asphalt resin can be stably loaded on the sponge body. Compared with the prior art, the asphalt which is wide in source and low in price is adopted as the main raw material of the modifier, the cost is effectively reduced, the preparation method is simple, and wide application prospects are achieved.

The application belongs to the technical field of compound preparation, and discloses a kind of 3-amido quinoline structure containing compound, its chemical structural formula is as follows: wherein, R1 is halogen;R2 is N-substituted five or six-membered nitrogen heterocyclic primary amine group or 3-substituted six-membered nitrogen heterocyclic primary amine group;R3 is 4-methylphenyl or 4-benzyl morpholinyl.The 4-methylphenyl or 4-benzyl morpholinyl substituted terminal alkyne ketone, 2-amino-5-halogen benzaldehyde is used as raw material to synthesize intermediate product, and the intermediate product is reacted with N-substituted five or six-membered nitrogen heterocyclic primary amine or 3-substituted six-membered nitrogen heterocyclic primary amine, to obtain a variety of 3-amido quinoline structure containing compounds, the raw material is widely sourced, low in price, green and environmentally friendly, and easy to operate, simple in condition, fast in reaction time, convenient in post-treatment, high in product yield, suitable for large-scale preparation, and has wide application prospect.

The present application belongs to the field of medicinal chemistry and pharmacotherapy, and particularly relates to a chalcone mannich base compound, a pharmaceutical composition and a preparation method and application thereof. The present application takes paeonol as a raw material, and obtains corresponding 3-substituted and 5-amino-methyl-substituted paeonol mannich base through mannich reaction of paeonol, polyoxymethylene and different organic amines. After the 3-substituted and 5-substituted paeonol mannich base is separated through column chromatography, the chalcone mannich base compound is obtained through Claisen-Schmidt reaction of the 3-substituted and 5-substituted paeonol mannich base and benzaldehyde containing different substituents. Experiments prove that the chalcone mannich base compound improves the physical and chemical properties of the chalcone mannich base and improves the drug efficacy, can solve the problem of poor water solubility, and has good anti-tumor cell proliferation activity.

The application provides a preparation method of a benzaldehyde aniline compound and relates to the technical field of organic synthesis. The preparation method provided by the application comprises the following steps: in a solvent, with an alkali as a promoter, under an atmosphere with an oxygen concentration of 20v100%, the temperature of a reaction system is controlled to be 50-70 DEG C, a diphenyl ketone compound I is reacted with an aniline compound II to generate a benzaldehyde aniline compound III, and the reaction product is subjected to column chromatography separation to obtain a pure benzaldehyde aniline compound III. The method has the beneficial effects that the reaction is simple, green and environment-friendly, the use of an expensive transition metal catalyst is avoided, the reaction condition is mild and controllable, and an environment-friendly byproduct is generated.

The invention discloses a preparation method of pesticide line thiophene, which comprises the following steps: under protective gas, dissolving benzaldoxime and 2-cyano thiophene in an organic solvent, slowly adding an oxidizing agent at the temperature of 20-30 DEG C, and after the reaction is completed, washing with water, extracting, concentrating and recrystallizing to obtain line thiophene, the oxidizing agent is selected from one or more of diacetoxy iodobenzene, [bis (trifluoroacetoxy) iodine] benzene and potassium peroxymonosulfonate. According to the preparation method of the pesticide line thiophene, the line thiophene is directly and efficiently synthesized through one-step reaction, and the yield is good. Compared with the existing synthesis route, the route is short, the solvent can be recycled and reused, the requirement on equipment is simple and corrosion-free, and a foundation is laid for further pilot scale production.

The application discloses cherry essence, and a preparation method thereof. The cherry essence comprises the following components in parts by weight: 80-98 parts of propylene glycol; 0.5-3 parts of benzaldehyde; 0.5-3 parts of ethyl acetate; 0.1-1 part of acetic acid; 0.1-1 part of gamma-decalactone; 0.1-0.8 part of ethyl butyrate; 0.01-0.2 part of butyric acid; 0.005-0.03 part of isoamyl alcohol; and 0.005-0.03 part of butanol. The preparation method comprises the following steps: taking all components of the cherry essence according to the proportion requirements, stirring all components of the cherry essence in a stirring container for 10-15 minutes, and then storing the mixture in a storage container. The cherry essence can be used as a food additive, and can be used in various foods to enhance the natural cherry aroma and natural taste of the foods. The aroma quality and stability of the cherry essence are superior to those of the same kind of essence in China.

The invention discloses a method for removing the fishy smell of chicken gizzards through multi-bacterium combined fermentation, and belongs to the technical field of poultry byproduct processing. According to the method disclosed by the invention, the chicken gizzards are subjected to fishy smell removal treatment by compounding the saccharomycetes Y4-1 and the bacillus SB. After fishy smell removal treatment, the content of key fishy smell substances including 1-octylene-3-alcohol, octanol, hexanal, nonanal and heptanal is greatly reduced, the total content is reduced from 25.15 mu g / g to 6.02 mu g / g and is reduced by 76.06%, heptanol, geranyl acetone, methyl heptanoate, methyl caprylate, glycerol monooleate, trans-2-decenal, 2-undecenal and other substances are completely removed, and the content of the key fishy smell substances is reduced by 76.06%. Meanwhile, elegant aroma components such as benzaldehyde and phenylacetaldehyde are generated. In conclusion, the saccharomycetes Y4-1 and the bacillus SB are compounded to remove fishy smell, so that the fishy smell substances of the chicken gizzards can be effectively removed, the flavor of the chicken gizzards can be further improved, and the edible value of the chicken gizzards is improved.

The invention provides a preparation process of (2E)-(3-hydroxy-4-methoxyl) cinnamyl aldehyde. The preparation process comprises the following steps: (1) adding 3-hydroxy-4-methoxyl benzaldehyde into an alkaline aqueous solution, and dissolving the 3-hydroxy-4-methoxyl benzaldehyde for later use; (2) introducing the solution obtained in the step (1) into a first inlet of a continuous flow reactor, wherein the flow velocity is 150.0-220mL / min; a vinyl acetate or acetaldehyde solution is introduced into a second inlet of the continuous flow reactor, the flow velocity is 10-30 mL / min, the retention time of the reaction solution in the continuous flow reactor is 5-10 min, and the reaction temperature is 50-100 DEG C; (3) adding reaction liquid of the continuous flow reactor into a reaction kettle for quenching under stirring; (4) after reaction quenching, filtering and collecting a precipitated solid crude product; (5) refluxing the obtained crude product in methanol, cooling, filtering and collecting the separated solid; and drying in vacuum until the weight is constant to obtain the (2E)-(3-hydroxy-4-methoxyl) cinnamyl aldehyde. According to the process, generation of dark impurities is avoided, the appearance quality and yield of the product are improved, continuous flow reaction is adopted, amplification is easy, and the amplification effect is avoided.

This invention discloses a method for synthesizing a key intermediate of cefdil, belonging to the field of pharmaceutical synthesis. Specifically, the method uses 2-chloro-3,4-dihydroxybenzaldehyde and 4-methoxybenzyl chloride as raw materials, and N,N-dimethylformamide as a solvent. The reaction is carried out under heating in the presence of a catalyst and a base. After the reaction is complete, hot water is added dropwise to the reaction solution, causing a solid to precipitate. The precipitated solid is then filtered, washed with water, and dried to obtain the product 2-chloro-3,4-bis((4-methoxybenzyl)oxy)benzaldehyde. This invention features a green and environmentally friendly synthesis process, simple operation, and convenient product purification. The obtained product has high yield and purity, with a liquid phase purity of 99.4% and a yield of 95.8%.