106 results about "Diphenylphosphine" patented technology

The invention discloses a catalyst for preparing ultrahigh molecular weight polyoxyethylene as well as a preparation method and application thereof, and relates to the technical field of catalyst preparation. The preparation method of the catalyst comprises the following steps: S1, carrying out a reaction on 6-hexamethylenediamine and allyl acrylate to generate an intermediate 1, S2, carrying out a reaction on the intermediate 1 and diphenylphosphine to generate an intermediate 2, S3, carrying out a reaction on the intermediate 2 and allyl bromide to generate an intermediate 3, and S4, carrying out a reaction on the intermediate 3 and 9-boron bicyclo [3.3. 1] nonane. The prepared catalyst is high in catalytic activity, ultrahigh molecular weight polyoxyethylene can be prepared, and the molecular weight distribution of the prepared ultrahigh molecular weight polyoxyethylene is narrow.

The invention relates to the field of phosphorus-nitrogen flame retardants, and discloses a preparation method and application of a novel phosphorus-containing nitrogen oxide flame retardant, the preparation method comprises the following steps: S1, under the protection of nitrogen, dissolving diphenylphosphinyl hydroxylamine and triethylamine in a tetrahydrofuran solvent to prepare a reaction substrate solution; s2, slowly dropwise adding a diphenylphosphinyl chloride solution into the solution, and then sufficiently carrying out the reaction in a staged heating and heating reflux mode; s3, cooling and filtering to remove solid byproducts generated by reaction, and concentrating filtrate to obtain a crude product solid; and S4, recrystallizing and purifying the crude product by using ethyl acetate, and finally heating and drying the obtained crystal under a vacuum condition to obtain the product. An N-O group is innovatively introduced into the molecular structure of the flame retardant, so that the effect of efficiently capturing gas-phase free radicals in cooperation with a phosphorus-containing group is achieved, and the substantive technical progress that the material can be endowed with excellent flame retardant property with extremely low addition amount is realized.

The invention discloses a triazine desulfurizer and a preparation method thereof, and belongs to the technical field of gas purification. The triazine desulfurizer is mainly prepared from the following raw materials in percentage by weight: 20 to 50 weight percent of triazine derivative, 10 to 15 weight percent of sterically hindered amine, 3 to 7 weight percent of stabilizer, 1 to 3 weight percent of synergist, 0.5 to 1.5 weight percent of penetrant, 0.5 to 1.5 weight percent of inhibitor, 1 to 2 weight percent of additive and the balance of water, the preparation method of the triazine derivative comprises the following steps: adding 2-(diphenylphosphino) ethylamine into a toluene solvent, adding a paraformaldehyde aqueous solution in batches under a stirring condition, and reacting for 2-8 hours to obtain the triazine derivative. According to the triazine desulfurizer and the preparation method thereof provided by the invention, the triazine derivative and the sterically hindered amine are taken as a host, and the stabilizer, the synergist, the penetrant, the inhibitor and the assistant are compounded, so that the scaling trend of the triazine desulfurizer in an oil and gas well can be slowed down, the dissolution rate of hydrogen sulfide and the mass transfer rate in a solution are increased, and the desulfurization reaction is promoted; the desulfurization effect and the desulfurization rate are improved, and meanwhile, a very good scale inhibition effect is also achieved.

The invention relates to the technical field of organic synthesis, in particular to 4-chloro-1-methyl-6H-heterochromene [3, 4-c] pyridine as well as a synthesis method and application of the 4-chloro-1-methyl-6H-heterochromene [3, 4-c] pyridine. The synthesis method comprises the following steps: (1) synthesizing 2-chloro-3-fluoro-4-iodine-5-methylpyridine from 2-chloro-3-fluoro-5-methylpyridine and an iodine elementary substance to obtain 2-chloro-3-fluoro-4-iodine-5-methylpyridine; (2) synthesizing 2-(2-chloro-3-fluoro-5-methylpyridine-4-yl) benzaldehyde from the 2-chloro-3-fluoro-4-iodo-5-methylpyridine, the 1, 1-bis (diphenylphosphine) ferrocene palladium dichloride, the tripotassium phosphate and the (2-formyl phenyl) boric acid, and further synthesizing the 2-(2-chloro-3-fluoro-5-methylpyridine-4-yl) benzaldehyde from the 2-chloro-3-fluoro-4-iodo-5-methylpyridine and the 1, 1-bis (diphenylphosphine) ferrocene palladium dichloride. And (3) synthesizing the 4-chloro-1-methyl-6H-heterochromene [3, 4-c] pyridine by using the 2-(2-chloro-3-fluoro-5-methylpyridine-4-yl) benzaldehyde and sodium tert-butoxide. The 4-chloro-1-methyl-6H-heterochromene [3, 4-c] pyridine compound constructed by the invention can be used for detecting the content of pesticide residue glyphosate.

The invention discloses a method for synthesizing a benzodithiepinone derivative through metal-free catalysis, and belongs to the field of organic synthesis. According to the method, benzo disulfonylphenol ketone and alkyne are taken as raw materials, a dual-catalysis system composed of triethylene diamine and bis (diphenylphosphine) methane is adopted, a heating reaction is performed in a 1, 4-dioxane solvent, and the target seven-membered sulfur heterocycle (benzo [e] [1, 4] dithiepin-5-ketone compound) is obtained through separation and purification. According to the method, the problem of regioselective sulfuration of alkyne is effectively solved through a synergistic catalysis mechanism of organic amine and organic phosphine, and high-precision cyclization reaction of benzobissulfonylphenol ketone and alkyne is realized. The process is mild in reaction condition, free of inert gas protection, simple and convenient to operate and good in functional group tolerance, the atom economy can reach 100%, and an efficient and practical synthesis way is provided for construction of the benzo [e] [1, 4] dithiepin-5-ketone compound with a novel structure.

The application relates to the technical field of catalysts, and discloses a palladium / alumina catalyst and a preparation method and application thereof. A Schiff base phosphine cyclodextrin ligand is synthesized through two-step reactions of nucleophilic substitution and Schiff base condensation, the molecular structure of the ligand covalently bridges the hydrophobic cavity of beta-cyclodextrin and the strong coordination site of diphenylphosphine through a rigid Schiff base bond; subsequently, the phosphine group of the ligand is coordinated with a palladium salt under a specific pH, and a uniform and stable palladium-ligand colloid precursor is formed under the assistance of a directing agent and a stabilizing agent; finally, the colloid is mixed with an alumina carrier for impregnation, drying, and a palladium / alumina catalyst is obtained. Through molecular design and process innovation, the problems of low activity, poor selectivity and insufficient stability of traditional catalysts are solved. When the catalyst is used for preparing hydrogen peroxide by hydrogenating anthraquinone, the hydrogenation efficiency is significantly improved, the selectivity is extremely high, and the cycle stability is excellent, so the catalyst has important industrial application value.

The invention discloses an MOF-derived Cu / t-ZrO2 bimetallic heterojunction catalyst as well as a preparation method and application thereof, and belongs to the technical field of photocatalyst materials. The preparation method of the catalyst comprises the following steps: adding an organic ligand suspension into a mixed solution of a copper source and 1, 2-bis (diphenylphosphine) ethane, and mixing and reacting under anhydrous and anaerobic conditions to obtain a copper-doped organic ligand material; the copper-doped organic ligand material and a zirconium source are mixed by using an organic solvent and then are subjected to a heating reaction to obtain a copper-doped zirconium-based metal organic framework material; and calcining the copper-doped zirconium-based metal organic framework material in an air atmosphere, and carrying out heat treatment in an inert atmosphere to obtain the MOF-derived Cu / t-ZrO2 bimetallic heterojunction catalyst. According to the MOF-derived Cu / t-ZrO2 bimetallic heterojunction catalyst disclosed by the invention, efficient, stable and low-cost solar energy-hydrogen energy conversion can be realized.

The invention belongs to the field of organic synthesis, and particularly relates to a synthetic method of a diaryl methane compound. A toluene derivative as shown in a formula 1, an aryl iodide as shown in a formula 2 and a styrene derivative as shown in a formula 3 are subjected to a reaction in the presence of a catalytic amount of PdCl2 (dppf) and 4, 6-di (diphenylphosphine) phenazine and an equivalent amount of LiN (SiMe3) 2 and CsF to synthesize the diaryl methane compound as shown in a formula 4. The coupling reaction of the toluene derivative, the aryl iodide and the styrene derivative is realized by adopting a catalytic amount of PdCl2 (dppf), and the palladium catalyst shows obvious catalytic performance.

The invention relates to a method for preparing triphenylphosphine, which comprises the following steps: a diphenylphosphine chloride raw material is subjected to heat treatment at the temperature of 280-420 DEG C to prepare triphenylphosphine, and at least part of phenylphosphine dichloride is removed in the heat treatment process.

The invention provides a green preparation method and application of diphenyl phosphine oxide. The preparation method comprises the following steps: step 1, mixing diphenyl alkoxy phosphine, water and Lewis acid, and fully stirring for reaction to obtain a reaction solution containing diphenyl phosphine oxide and alcohol; step 2, distilling the reaction liquid, washing with water, standing, separating liquid, collecting an organic phase, drying the organic phase, and cooling and crystallizing to obtain diphenylphosphine oxide; and step 3, rectifying and purifying the distilled alcohol, and pumping the distilled acid and water washing liquid into a reaction kettle for cyclic catalysis. The diphenylalkoxyphosphine is used as a raw material and is subjected to hydrolysis reaction with water under the catalysis of the lewis acid to generate diphenylphosphine oxide and alcohol, the lewis acid can be continuously returned to the reaction kettle to participate in the reaction after being subjected to subsequent distillation, the synthesis process is simple, the atom economy is high, the reaction principle is simple, the conditions are easy to control, and the method is green and environment-friendly and can be used for industrial production.

The invention discloses a preparation method and application of 1, 4-bis (diphenylphosphine) butane platinum dichloride (II), and the preparation method comprises the following steps: (1) mixing absolute methanol and dichloromethane, carrying out deoxidation treatment, and adding 1, 4-bis (diphenylphosphine) butane into the mixture; (2) dissolving potassium chloroplatinite in distilled water, filtering insoluble impurities, dropwise adding the potassium chloroplatinite into the reaction system in the step (1) under the protection of inert gas while keeping a stirring state, and after dropwise adding, heating, refluxing and stirring for reaction; (3) carrying out filter pressing under the protection of inert gas, passing through a silica gel column, and collecting filtrate; (4) concentrating the filtrate, and then adding an organic solvent for pulping; and (5) carrying out filter pressing under the protection of inert gas, washing a filter cake, and carrying out vacuum drying. According to the preparation method, the product yield is high, the purity is high, and the obtained 1, 4-bis (diphenylphosphine) butane platinum dichloride (II) is used for hydrogenation reaction of carbonyl compounds and has good catalytic performance.

The application provides a method for constructing a C-P bond through a nickel-catalyzed Hirao reaction, comprising the following steps: coupling a substituted aromatic compound 1 and a diphenyl phosphine oxide 2 in an organic solvent in the presence of a nickel catalyst, an additive and a base to generate an aromatic phosphine oxide compound 3, and the reaction formula is as follows: wherein X is any one of F, Cl, Br, I, OTf, B(OH)2 and OCF3; and Ar is an aromatic group. The method has the effects of universality of substrates, simple operation, mild conditions, low cost of noble metal catalysts and phosphine ligands and high yield.

The application discloses a method for vitamin A isomerization, and particularly relates to a method for generating all-trans vitamin A by performing isomerization reaction on VA crude oil in a solvent in the presence of a palladium catalyst, an alcohol amine type auxiliary agent and a diphenyl phosphine type auxiliary agent under an inert atmosphere. The method can efficiently isomerize 13-cis vitamin A into all-trans vitamin A while inhibiting the conversion of all-trans vitamin A into 9-cis vitamin A. After the reaction is completed, the conversion rate of 13-cis vitamin A is greater than or equal to 95%, the selectivity of all-trans vitamin A is greater than or equal to 99%, and no 9-cis vitamin A is generated.

The invention provides a preparation method of a novel chiral thiourea / phosphine bifunctional organic catalyst with a cis-cyclic 1, 2-phosphinamine skeleton and application of the novel chiral thiourea / phosphine bifunctional organic catalyst in an asymmetric catalytic reaction. The chiral organic catalyst is prepared by taking cis chiral 2-(diphenylphosphine)-1, 2, 3, 4-tetrahydro-1-naphthylamine and an isothiocyanate compound as raw materials through a one-step reaction under a mild condition. The chiral thiourea / phosphine bifunctional organic catalyst is simple to prepare and stable in property, and shows excellent catalytic activity and stereoselectivity in an asymmetric hydrosilylation reaction of o-amido benzophenone.

The invention relates to the technical field of chromatographic packing, in particular to phosphine-containing ligand modified silica gel chromatographic packing and a preparation method thereof.The preparation method comprises the steps that firstly, porous silsesquioxane microspheres containing diphenylphosphine ligands are designed and synthesized to serve as a functional unit, and modified bridged silane containing a phenyl ether structure serves as an alkali-resisting enhancing unit; then copolycondensation is carried out on the units and tetraethoxysilane through a sol-gel method, an organic-inorganic hybrid silica gel skeleton is constructed, and finally the pore channel structure of the filler is optimized through a two-step pore expanding technology. According to the method, a phosphine ligand is firmly embedded into a silica gel skeleton in a covalent bond form, and modified bridged silane containing a phenyl ether structure is used as a part of the skeleton to provide hydrophobic protection and space stabilization effects, so that long-term stability of the filler in a strong alkaline environment and high-capacity and high-selectivity adsorption of metal ions are synergistically realized.

The application discloses a high-temperature-resistant polyvinyl chloride adhesive tape and a preparation method thereof, and belongs to the technical field of polymer materials and adhesive products. The high-temperature-resistant polyvinyl chloride adhesive tape comprises the following raw materials in parts by weight: synergistically modified polyvinyl chloride, diphenyl phosphine oxide, chlorinated polyethylene, diisononyl phthalate, antimony trioxide, calcium stearate, zinc stearate, an antioxidant and a leveling agent; the synergistically modified polyvinyl chloride is obtained by introducing catechol structures on the surface of polyvinyl chloride through dopamine self-polymerization deposition, forming a dynamic borate ester structure with 3-aminobenzoic acid, and constructing a Si-O-Si network structure through hydrolytic condensation reaction of octa(3-aminopropyl)silsesquioxane and N-(beta-aminoethyl)-gamma-aminopropyl triethoxysilane. The dopamine-borate ester-silicone synergistic network structure is constructed, and the diphenyl phosphine oxide is introduced for function regulation, so that the heat resistance, mechanical properties and dimensional stability of the polyvinyl chloride adhesive tape are significantly improved.

The invention relates to the technical field of phosphorus chemical synthesis, in particular to an industrial production method and application of 1, 2-bis (diphenylphosphinoxy) ethane, and the industrial production method of 1, 2-bis (diphenylphosphinoxy) ethane comprises the following steps: step 1, preparing an alkali solution; step 2, substitution reaction; step 3, product separation; step 4, product drying; and 5, recovering water, toluene and potassium chloride. The method has the advantages of few operation units, no three wastes, easily controllable conditions, realization of continuous production, and meeting of industrial production requirements.

The invention discloses an alpha-fluoro alpha, beta-unsaturated amide derivative as well as a synthesis method and application thereof. The preparation method comprises the following steps: by taking amyl-1, 1, 2-trifluoro-1, 4-diene which is simple and convenient to prepare and a cheap and abundant amine compound as raw materials, an allyl palladium chloride dimer as a transition metal catalyst, 1, 4-bis (diphenylphosphine) butane as a ligand and 2, 5-di-tert-butylbenzoquinone as an oxidant, reacting in an organic solvent at a proper temperature under a nitrogen condition, thereby obtaining the 1, 1, 2-trifluoro-1, 4-diene compound. The alpha-fluoro alpha, beta-unsaturated amide derivative is obtained with good yield, and the structural formula of the derivative is shown in the specification. The synthesis method disclosed by the invention has the characteristics of simplicity and convenience in operation, mild conditions, greenness, economy, wide substrate compatibility, high chemical selectivity and high regioselectivity, and solves the technical problem that the synthesis conditions of the alpha-fluoro-alpha, beta-unsaturated amide derivative are complicated and harsh. Meanwhile, the alpha-fluoro drug molecules can be efficiently and highly selectively obtained, and the method has a wide application prospect.

This invention relates to a lysosome-targeting fluorescent dye based on the BODIPY structure and its synthesis method, belonging to the field of organic fluorescent dyes. The invention designs and synthesizes the lysosome-targeting fluorescent dye BDP. The dye molecule uses BODIPY as the parent structure, and a novel lysosome-targeting fluorescent dye molecule is synthesized by introducing diphenylphosphine salt and tert-butyloxycarbonyl groups. The synthetic route of this dye is simple, it possesses excellent photostability, and exhibits good resistance to interference from ions, amino acids, and viscosity. Furthermore, this dye demonstrates superior fluorescence performance in a variety of common solvents, with fluorescence quantum yields exceeding 0.70. Experimental results show that this fluorescent dye can precisely target lysosomes in living cells, demonstrating promising applications in the field of bioimaging.

This invention discloses an indium phosphide quantum dot-bismuth tungstate composite material, its preparation method, and its application, relating to the field of photocatalytic materials technology. The preparation method includes the following steps: Indium precursor is added to oleylamine and mixed; the mixture is gradually heated and kept at a constant temperature under nitrogen protection; then, tris(diphenylphosphine) is added at 170-190°C to react and obtain indium phosphide quantum dots; bismuth nitrate is dispersed in water, and hexadecyltrimethylammonium bromide and sodium tungstate are added sequentially, followed by a hydrothermal reaction to obtain bismuth tungstate microflowers; indium phosphide quantum dots and bismuth tungstate microflowers are added to deionized water, mixed evenly, heated to react, cooled to room temperature, washed, and dried to obtain the indium phosphide quantum dot-bismuth tungstate composite material. This invention also discloses the indium phosphide quantum dot-bismuth tungstate composite material prepared by the above method and its application. This composite material has the function of photocatalytic H2O2 production and has significant application value in the treatment of coking wastewater.

The invention relates to the technical field of organic alcohol synthesis, and discloses a method for synthesizing isononyl alcohol. The method comprises the following steps: (1) mixing octylene, a rhodium catalyst and a phosphine ligand, then introducing synthesis gas into the obtained mixture, and carrying out hydroformylation reaction to obtain isononanal; (2) in the presence of a hydrogenation catalyst, mixing the isononanal with hydrogen for hydrogenation reaction; wherein the phosphine ligand is selected from two or more of triphenyl phosphite, tris (2, 4-di-tert-butylphenyl) phenyl phosphite, triphenylphosphine, 6, 6 '-{[5, 5'-dimethoxy-3, 3 '-bis (2-methyl-2-propyl)-2, 2'-biphenyl diyl] bis (oxy)} bis [dibenzo (d, f) (1, 3, 2) dioxaphosphoheptane] and 4, 5-bis (diphenylphosphine)-9, 9-dimethyl xanthene. According to the method, the conversion rate of mixed octylene in the hydroformylation process and the selectivity and yield of isononyl aldehyde can be remarkably improved, so that the yield of isononyl alcohol is improved, reaction conditions are mild, and the method has remarkable economic value and wide industrial application prospects.

The application discloses a method for constructing a cycloalkene-quinolinone axial chiral compound through a Heck reaction. The method uses a quinolinone compound containing central chirality as a substrate, uses palladium acetate (Pd(OAc)2) and 4,5-bisdiphenylphosphine-9,9-dimethylxanthene (Xantphos) as a catalyst, uses silver phosphate (Ag3PO4) as an alkali, and uses toluene as a solvent to prepare a cycloalkene-quinolinone axial chiral compound. The compound can be reacted with diisobutylaluminum hydride to realize conversion of a functional group. The method has mild reaction conditions, raw materials are easy to obtain, the product has excellent enantioselectivity, and has excellent yield, and thus provides a new method for synthesizing a cycloalkene-quinolinone axial chiral compound.

The present application relates to the technical field of chromatographic packing, in particular to a kind of phosphine ligand modified silica gel chromatographic packing and preparation method thereof, the present application first designs and synthesizes the porous silsesquioxane microspheres containing diphenyl phosphine ligand as functional unit, and the modified bridged silane containing phenyl ether structure as alkali-resistant reinforcing unit, then by sol-gel method, the above unit is copolymerized with tetraethyl orthosilicate, constructs organic-inorganic hybrid silica gel skeleton, finally, the pore structure of packing is optimized by two-step hole expansion process;The method makes phosphine ligand firmly embedded in the interior of silica gel skeleton in the form of covalent bond, and the modified bridged silane containing phenyl ether structure provides hydrophobic protection and space stabilization effect as part of the skeleton, so as to realize the long-term stability of packing in strong alkaline environment and high capacity, high selectivity adsorption of metal ions.

The invention discloses a metal nanocluster and application of the metal nanocluster in catalysis of sec-enaminone photooxidation reaction. The molecular formula of the metal nanocluster is [Au13Cd2 (BINAP) 3 (PET) 6Y2] < + >, wherein Y is F, Cl, Br or I, and BINAP is a diphosphine ligand 1, 1 '-binaphthyl-2, 2'-bis (diphenylphosphine). According to the invention, a novel catalyst with NIR-II strong absorption (to 1500 nm) and high-efficiency energy transfer characteristics is constructed by accurately modifying a light functional ligand BINAP on the surface of the nanocluster, and high-efficiency light-driven catalysis in a deep reaction system, a biocompatible environment and an industrial scale is realized.

The preparation method of the 3-phenylcoumarin derivative comprises the following steps: mixing 2-hydroxybenzaldehyde, a benzyl halide compound, a carbonyl metal compound, palladium acetate, 4, 5-bis (diphenylphosphine)-9, 9-dimethyl xanthene, sodium carbonate and dimethyl sulfoxide, stirring and reacting at 70-90 DEG C for 13-15 hours, filtering, washing and drying to obtain the 3-phenylcoumarin derivative. And then carrying out post-treatment on the reaction product to obtain the 3-phenylcoumarin derivative. The solid carbonyl metal compound is adopted as a carbonyl source, and a specific catalyst system and mild reaction conditions are combined, so that the 3-phenylcoumarin derivative can be efficiently, safely and easily synthesized, and the method has a relatively good application prospect.

The invention provides a binuclear cobalt carbonyl complex coordinated with 4, 5-bis (diphenylphosphine-9, 9-dimethyl xanthene (xantphos), a preparation method of the binuclear cobalt carbonyl complex and application of the binuclear cobalt carbonyl complex in an alkyne hydrogen silicification reaction. Specifically, the invention provides a 4, 5-bis (diphenylphosphine-9, 9-dimethyl xanthene coordinated binuclear cobalt carbonyl complex with a structure as shown in a formula I which is described in the specification. The complex can efficiently and highly selectively catalyze the anti-Markov hydrosilicification reaction of alkyne under certain conditions, and alkenyl silicon compounds with various purposes are obtained.

The application discloses a 2-phenyl-4-pinacol boron-based-2,1-boronazanaphthalene, a 2-phenyl-4-pyrimidyl-2,1-boronazanaphthalene compound and a preparation method thereof, and belongs to the technical field of organic synthesis chemistry. The method is based on a copper-catalyzed selective dehydrogenation boronation reaction strategy, 2-phenyl-2,1-boronazanaphthalene and pinacol diboron ester are used as raw materials, CuCl is used as a catalyst, 4,5-bis(diphenylphosphino)-9,9-dimethyloxyanthracene is used as a ligand, 2-adamantanone is used as an additive, p-xylene is used as a solvent, and 2-phenyl-4-pinacol boron-based-2,1-boronazanaphthalene is efficiently obtained. The 2-phenyl-4-pinacol boron-based-2,1-boronazanaphthalene compound synthesized by the application can be used as a key intermediate, is efficiently converted through a C-B bond, and is convenient for synthesizing a 2-phenyl-4-pyrimidyl-2,1-boronazanaphthalene compound, thereby providing a new way for functional modification of boronazacyclic compounds.

The invention belongs to the technical field of luminescent materials, and particularly relates to a Mn (II)-based complex luminescent material as well as a preparation method and application thereof. The chemical formula of the manganese (II)-based complex luminescent material is [Mn (DPPPO) Cl2] n, and DPPPO is 1, 3-bis (diphenylphosphinyloxy) propane. Under the stimulation of methanol, methanol molecules are combined with the [Mn (DPPPO) Cl2] n through hydrogen bonds to induce reconstruction of a crystal structure, so that the [Mn (DPPPO) Cl2] n is gradually converted into [Mn2 (DPPPO) 4Cl2] Cl2; therefore, the specific response to the methanol steam is realized; the technical problem that an existing manganese-based metal halide is poor in selective recognition and detection capacity on specific target vapor molecules, and consequently the recognition specificity is poor is solved. And recovery can be realized through heating, so that reversible use of the material is realized.

The invention discloses a chlorine-containing monophosphine compound as well as a preparation method and application thereof, and the chlorine-containing monophosphine compound is (2-formyl phenyl) diphenylphosphine-2, 6-dichloro-1, 4-phenylenediamine; the preparation method comprises the following steps: sequentially adding 2, 6-dichloro-1, 4-phenylenediamine and (2-formylphenyl) diphenylphosphine into an organic solvent I in an inert gas atmosphere, reacting for a certain time at a certain temperature, cooling and filtering to obtain a crude product; and dissolving the obtained crude product in a dichloromethane / normal hexane mixed solution, cooling, volatilizing and crystallizing, filtering and drying to obtain the chlorine-containing monophosphine compound. The chlorine-containing monophosphine compound is applied as a fluorescent probe to detect heavy metal ions, and the heavy metal ions in a solution are detected by utilizing the fluorescence intensity enhancement effect of the chlorine-containing monophosphine compound on the heavy metal ions. The preparation method disclosed by the invention is simple and convenient to operate, relatively mild in reaction condition, relatively low in raw material price and low in process cost, and has an application prospect of industrial production.

This invention discloses a metal-free catalytic synthesis method for benzo[e][1,4]dithioheptan-5-one derivatives, belonging to the field of organic synthesis. The method uses benzo[e][1,4]dithioheptan-5-one compounds as raw materials, employing a dual-catalytic system composed of triethylenediamine and bis(diphenylphosphine)methane, and reacts under heating in a 1,4-dioxane solvent. After separation and purification, the target seven-membered thioheptan-5-one compounds are obtained. This method effectively solves the regioselective sulfidation problem of alkynes through the synergistic catalytic mechanism of organic amines and organic phosphines, achieving a highly precise cyclization reaction between benzo[e][1,4]dithioheptan-5-one compounds. The process features mild reaction conditions, requires no inert gas protection, is simple to operate, exhibits good functional group tolerance, and achieves 100% atom economy, providing an efficient and practical synthetic route for the construction of novel benzo[e][1,4]dithioheptan-5-one compounds.