841 results about "Ethanol" patented technology

The invention discloses a synthetic method of a water soluble ultraviolet light absorber BP-9. The method mainly comprises the following process steps: (1) carrying out methylation on the main raw materials of 2, 2', 4, 4'-tetrahydroxyl benzophenone, a transition metal salt catalyst and a mixed solvent which is prepared from dichloroethane and anhydrous ethanol in equal parts by weight to obtain 2, 2'-dihydroxyl-4, 4'-dimethoxyl benzophenone; (2) carrying out sulfonation reaction on the main raw materials of methylate, sulfamic acid and C1-C3 halohydrocarbon to obtain 2, 2'-dihydroxyl-4, 4'-dimethoxyl benzophenone-5, 5'-disulfonic acid; and (3) carrying out neutral reaction on the main raw materials of sulfonated product, inorganic base and ethanol water to finally obtain the BP-9 product. The synthetic method disclosed by the invention is few in reaction step, low in cost, high in product purity and stable in quality, and raw materials are easily available.

The invention belongs to the technical field of conductive adhesives, and particularly relates to a salt-fog-resistant waterborne conductive adhesive and a preparation method thereof.The salt-fog-resistant waterborne conductive adhesive is mainly prepared from, by weight, 5-10 parts of salt-fog-resistant waterborne polyurethane; 5 to 10 parts of water-based tackifying resin; 30 to 50 parts of conductive silver powder; 10 to 20 parts of ethanol; 2-10 parts of an anti-hydrolysis agent; and 10-30 parts of deionized water. According to the salt-fog-resistant aqueous conductive adhesive, polyurethane resin with polytetrahydrofuran alcohol and polycaprolactone polyol as main structures is used as matrix resin, a system is endowed with excellent water resistance and salt-fog resistance, the salt-fog-resistant aqueous conductive adhesive shows outstanding hydrolysis-resistant stability after being cured, and the salt-fog-resistant aqueous conductive adhesive and the conductive silver powder have a synergistic effect, so that the anti-settling performance is effectively improved.

The invention relates to the field of medical materials and medical instruments, and discloses a dry bioprosthetic valve and a preparation method thereof.The preparation method comprises the following steps that S1, pericardium and a cross-linking agent solution are mixed for a cross-linking reaction; s2, carrying out first dehydration treatment on the crosslinked pericardium by adopting a first dehydration solution with gradually increased concentration gradient under an ultrasonic condition; and S3, carrying out second dehydration treatment on the pericardium subjected to the first dehydration treatment by adopting a second dehydration solvent, so as to obtain the dried bioprosthetic valve. According to the preparation method provided by the invention, ethanol, isopropanol and water in a specific proportion are adopted to prepare a dehydration solution with gradient concentration, and two-step dehydration drying is carried out in combination with the physical effect of an ultrasonic technology and glycerol, so that rapid rehydration of the bioprosthetic valve is realized, and the original shape and mechanical property of the bioprosthetic valve can be better recovered after rehydration; and the immediate hemodynamic stability of the valve is improved.

The invention relates to the technical field of pharmaceutical preparations, and provides a minoxidil film coating agent as well as a preparation method and application thereof. The minoxidil film coating agent provided by the invention comprises 40-60% of propylene glycol, 3-7% of polyvinyl alcohol, 20-30% of ethanol, 1-7% of minoxidil and the balance of water. According to the invention, propylene glycol is taken as a solvent, a plasticizer and a transdermal absorption enhancer, polyvinyl alcohol is taken as a film-forming material, and ethanol is taken as a volatile agent, after administration, ethanol is volatilized to promote film formation of polyvinyl alcohol, and propylene glycol enhances the plasticity of the formed film, so that the effect of reducing liquid medicine loss is achieved, the local medicine concentration is increased, and the bioavailability is improved. The minoxidil liniment disclosed by the invention has excellent skin permeability, can effectively convey a medicine to a required part, and can ensure that the medicine is released at a fixed position of the skin and is accurately administered in a medicine release process, so that the stimulation of liquid medicine flow to other parts is reduced, and a good treatment effect is achieved.

The invention provides a hole transport layer precursor solution, a hole transport layer, a preparation method and application of the hole transport layer, and a perovskite cell, and belongs to the technical field of hole transport layers. The hole transport layer precursor solution comprises a self-assembled single molecule and an organic solvent; the organic solvent comprises a solvent A, a solvent B and a solvent C; the solvent A comprises more than one of a phosphate ester solvent and an alcohol ether solvent; the solvent A contains four hydrogen bond receptors; the boiling point of the solvent A is 215-290 DEG C; the solvent B comprises more than one of ethanol, isopropanol, normal propyl alcohol, butanol, ethylene glycol and N, N-dimethylformamide; the solvent C comprises more than one of ethyl acetate and normal hexane. A ternary hydrogen bond network is formed through the solvent A, the solvent B and the solvent C, the agglomeration degree of SAM molecules is remarkably reduced, and the device performance is improved.

This invention discloses a method for preparing an air-based hydrophilic-oleophobic coating, comprising the following steps: a) adding a silane coupling agent to ethanol to obtain solution A; b) first adding perfluorooctanoic acid and sodium hydroxide to ethanol to obtain a sodium perfluorooctanoate ethanol solution, then adding at least two types of hydrophilic nanoparticles of the same particle size to the sodium perfluorooctanoate ethanol solution to obtain solution B; c) adding a fluorinated surfactant and at least two types of hydrophilic nanoparticles of the same particle size to ethanol to obtain solution C; d) first mixing solution B and solution C uniformly to obtain solution D, then slowly adding solution A dropwise to solution D to obtain suspension E; e) spraying suspension E onto the surface of a substrate and drying at 55-65°C for 1-3 hours to obtain an air-based hydrophilic-oleophobic coating. The preparation method of this invention is simple, and the resulting coating exhibits excellent hydrophilicity and oleophobicity, acid and alkali resistance, salt resistance, and oil stain resistance.

The invention discloses high-purity oxamide with concentrated particle size and spherical morphology, a preparation method of the high-purity oxamide and application of the high-purity oxamide in preparation of a slow-release fertilizer, and belongs to the technical field of oxamide synthesis and application. The method comprises the following steps: mixing an ammonia-alcohol solution and an alcohol ester solution, conveying the mixed solution into a series tubular reactor for reaction, and then conveying the mixed solution into a parallel tubular reactor for reaction after pressure stabilization and flow equalization to obtain a reaction solution containing oxamide; performing flash evaporation on the reaction liquid to obtain flash evaporation liquid and flash evaporation gas, and performing solid-liquid separation on the flash evaporation liquid to obtain solid oxamide and filtrate; and drying the solid oxamide to obtain the oxamide. The method realizes high conversion rate and high purity, and the product has ultrafine particle size distribution. The purity of the prepared oxamide is greater than or equal to 99%, the D50 particle size is concentrated to 50 + / -15 microns, the spherical morphology is uniform, the release is stable, and the oxamide has a very good effect in preparation of long-acting slow-release fertilizers and combustion inhibitors and research on the nitrogen utilization rate.

The invention provides a platycodon grandiflorum extract for preventing or / and treating non-alcoholic fatty liver disease, which is prepared by the following steps: extracting a platycodon grandiflorum medicinal material with absolute ethyl alcohol to obtain a platycodon grandiflorum extract PG-1; and extracting platycodon grandiflorum dregs with water to obtain the platycodon grandiflorum extract PG-2. The invention also provides a preparation method and application of the platycodon grandiflorum extract. The platycodon grandiflorum extract disclosed by the invention has an obvious effect of treating the non-alcoholic fatty liver disease, and compared with an atorvastatin calcium tablet, the medicinal effect of the platycodon grandiflorum extract is equivalent to that of the atorvastatin calcium tablet in two groups of extracts PG-1 and PG-2-1; according to the present invention, the pharmacological effects of the extracts PG-2 and PG-2-2 groups are significantly superior to the pharmacological effects of atorvastatin calcium tablets, and particularly, the separated and purified extracts PG-2-2-1, PG-2-2-2 and PG-2-2-3 can provide significant effects under the milligram-level use amount, and provide the pharmacological effects better than the pharmacological effects of the single platycodin D so as to provide the synergistic effect. In the preparation process of the PG-2-2-3, only ethanol with different concentrations needs to be used for separation and purification, so that the production cost is greatly reduced, and meanwhile, the pollution of chemical reagents is reduced.

The invention belongs to the technical field of forest chemical industry and natural perfume extraction and separation, and particularly discloses a superheated steam distillation separation and recovery method for perfume components in cinnamon oil rectifying still residues. The method comprises the following steps: processing the cinnamon oil rectifying still residues by adopting a steam distillation method taking normal-pressure superheated steam as a desorption medium, carrying out condensation cooling and phase separation on distilled oil-water mixed gas, and collecting oily liquid or crystalline solid containing cinnamon spice components, and carrying out one or more physical isolation methods such as freezing crystallization, vacuum fractionation or rectification, recrystallization and the like to obtain natural cinnamon monomer spices such as o-methoxycinnamaldehyde, o-methoxycinnamic acid, phenethyl alcohol and the like. The method has the advantages of low equipment investment, simple and feasible operation, low production cost, clean and pollution-free process, good operation safety, high industrial application feasibility and the like.

The invention discloses a steel cylinder cleaning method. The method comprises the steps that ethyl alcohol is injected into a steel cylinder; rolling the steel cylinder filled with the ethanol for multiple times to rinse the inner wall of the steel cylinder, and then emptying the ethanol in the steel cylinder; injecting ultrapure water into the steel cylinder cleaned by the ethanol; rolling the steel cylinder filled with the ultrapure water for multiple times, rinsing the inner wall of the steel cylinder, and then emptying the ultrapure water in the steel cylinder; nitric acid is injected into the steel cylinder cleaned by the ultrapure water, metal ions in the steel cylinder are dissolved, and then the nitric acid in the steel cylinder is emptied; injecting ultrapure water into the steel cylinder to rinse the steel cylinder, and emptying the ultrapure water in the steel cylinder; taking the discharged ultrapure water as a sample, and detecting the content of residual metal ions in the steel cylinder; according to the obtained metal ion content, whether the steel cylinder meets the cleanliness requirement or not is judged, if the cleanliness requirement is met, a small amount of nitric acid is added into the steel cylinder, sampling detection is conducted after the steel cylinder is moistened and washed, and if the test result is consistent with the previous metal ion content, the steel cylinder is clean. According to the steel cylinder cleaning method, external source introduction is avoided while metal ion impurities in the steel cylinder are treated.

The invention discloses a bionic tree-shaped evaporator based on hollow microtubes and application thereof, and relates to the technical field of solar water treatment.The bionic tree-shaped evaporator is prepared through the following steps that bacterial cellulose hybrid spinning solution serves as shell layer fluid, absolute ethyl alcohol serves as core layer fluid, the shell layer fluid and the core layer fluid are co-extruded into an ethyl alcohol coagulating bath, curing is conducted, washing is conducted with ethyl alcohol and deionized water in sequence to be neutral, and drying is conducted to obtain the bionic tree-shaped evaporator. A hollow hybrid microtube is obtained; and arranging and fixing the plurality of hollow hybrid microtubes on a bracket according to a tree-shaped branch structure to obtain the bionic tree-shaped evaporator. The bionic tree-shaped evaporator prepared by the invention has excellent mechanical flexibility, salt tolerance and purification efficiency, and provides a new material and a new scheme for efficient and sustainable solar seawater desalination and wastewater treatment.

The invention provides a method for preparing a fluorocarbon resin super-hydrophobic coating, and relates to the field of coatings. The preparation method comprises the following steps: adding nano silicon dioxide into a mixture of ethanol and water, stirring, and carrying out ultrasonic dispersion to obtain a dispersion liquid; dropwise adding a silane coupling agent into the dispersion liquid, ultrasonically dispersing uniformly, heating and stirring in a water bath, cooling to room temperature, centrifuging, washing a solid with absolute ethyl alcohol, and drying to obtain nano silicon dioxide powder; s2, mixing the nano silicon dioxide powder prepared in the step S1 with an N-methyl pyrrolidone solution of PVDF, and uniformly stirring to obtain coating slurry; and taking an absolute ethyl alcohol solution of epoxy resin as a primer, spraying the primer on the cement surface, curing, spraying the coating slurry, and curing to obtain the coating. The super-hydrophobic coating plays a role in protecting and strengthening the cement matrix, and the mechanical strength of the surface of the cement matrix is improved.

The invention discloses preparation and application of a reductive amination catalyst. The preparation method of the catalyst comprises the following steps: step 1, preparing an SrTiO3 carrier; step 2, loading a nickel source into the prepared SrTiO3 carrier to form a nickel-loaded SrTiO3 catalyst precursor; and step 3, roasting the SrTiO3 catalyst precursor to obtain the SrTiO3 loaded nickel catalyst. Large-scale production of the non-noble metal catalyst is realized by adopting a co-precipitation method and an impregnation method which are simple in process and environment-friendly under the condition of room temperature, the obtained material can be used for reductive amination reaction of acetophenone under the condition of taking water as a solvent and shows excellent catalytic performance, and after 50 times of application, the acetophenone conversion rate is gt; the selectivity of alpha-phenylethylamine is gt; the selectivity of the alpha-phenethyl alcohol is 1t; and 2%.

The invention discloses an on-line extraction self-optimization method for acanthopanax sessiliflorus flavone based on reinforcement learning. According to the method, multi-source data in the extraction process is collected in real time, and a fusion feature vector is generated after preprocessing; establishing a mapping relation from the feature vector to the contents of rutin, quercetin, kaempferol and hyperoside by using an offline test sample, and constructing a virtual measurer capable of outputting a target flavone composition vector and uncertainty thereof; constructing a safety domain boundary according to a solvent flash point temperature, an equipment tolerance temperature upper limit and a component thermal degradation temperature threshold, and calculating a time-varying safety constraint threshold in combination with uncertainty; performing linkage optimization on the temperature, the ethanol volume fraction, the solid-to-liquid ratio, the soaking time and the circulating flow by adopting a reinforcement learning strategy, and comprehensively considering flavone composition deviation and solvent energy consumption by a reward function; and finally, outputting the optimized parameters to extraction equipment for execution. According to the method, online, lossless and self-adaptive process optimization control is realized, inter-batch fluctuation is remarkably reduced, and the resource utilization efficiency is improved.

The application provides a self-floating double-layer solar evaporator with Janus characteristics and a preparation method and application thereof, and belongs to the technical field of solar evaporator preparation. The preparation method is as follows: gourd sponge is calcined and ground into carbonized gourd sponge powder, which is dispersed into a polyvinyl alcohol / sodium alginate solution to obtain a dispersion liquid containing the carbonized gourd sponge; the gourd sponge is used as a support, and the polyvinyl alcohol / sodium alginate solution and the dispersion liquid containing the carbonized gourd sponge are sequentially poured, and a double-layer gel containing vertical pores is formed by stepwise freezing; the double-layer gel is thawed and crosslinked through a calcium chloride solution, washed, and freeze-dried to obtain a double-layer aerogel; the photo-thermal surface of the aerogel is sprayed with a silane coupling agent / ethanol solution to complete hydrophobic modification, and the self-floating double-layer solar evaporator with Janus characteristics is obtained. The solar evaporator prepared by the application has a high evaporation rate and has a wide application prospect in the fields of seawater desalination and wastewater treatment.

The invention discloses a surfactant for PVB (polyvinyl butyral) resin powder prepared on the basis of a microreactor and a preparation method of the surfactant. The preparation method of the surfactant comprises the following steps: mixing and dissolving polyvinyl alcohol and water into a polyvinyl alcohol aqueous solution to prepare a solution A, putting acrylic acid or acrylate into a container, adding a mixed solution of ethanol and water, stirring, and adding a mixed solution of ethanol and water to prepare a solution B; respectively injecting the solution A and the solution B into a high-pressure piston intermediate container, connecting the high-pressure piston intermediate container with an inlet of a microreactor through a pipeline, starting a delivery pump, and synchronously injecting liquid into the microreactor; and carrying out graft polymerization reaction in the microreactor, enabling the reacted liquid to flow out of the microreactor, and carrying out cooling, dehydration and drying treatment to obtain the surfactant. The prepared surfactant has surface activity functions such as good dispersity, thermal stability and environment-friendly performance, and can be applied to the fields of high-performance PVB powder, optical materials, ink resin and the like.

The invention relates to the technical field of palladium recovery, in particular to a method for recovering palladium. According to the technical scheme, the method comprises a precipitant pre-synthesis stage, a targeted palladium precipitation stage and a multi-stage reduction purification stage, and the precipitant pre-synthesis stage comprises the step of adding 10-15 parts by mass of butanedione, 18-30 parts by mass of hydroxylamine hydrochloride and 0.1-0.3 part by mass of iron phthalocyanine into a reaction kettle. Through a composite precipitator system and a multi-stage reduction process, the method has safety and high efficiency: flammable and explosive solvents such as ethanol and highly toxic reducing agents such as hydrazine hydrate are not needed, so that the potential safety hazard of production and the environment-friendly treatment cost are remarkably reduced; high-selectivity capture and efficient reduction of palladium are achieved through magnetic separation of magnetic nano-microspheres, induced precipitation of nitrogen-doped graphene quantum dots and a staged temperature-control and pressure-control reduction technology, the palladium recovery rate and purity are high, the process period is short, operation is controllable, and the method is suitable for industrial continuous production.

The invention discloses a directional preparation method of a high-stability dark brown pigment and an application of the high-stability dark brown pigment in an acid beverage, and relates to the technical field of food additives. The preparation method comprises the following steps: S1, crushing raw dark green tea raw materials, mixing the crushed raw dark green tea raw materials with water, adjusting the pH value to 9-12, carrying out heating extraction, and collecting a supernatant; s2, repeatedly concentrating the supernate to obtain a concentrated solution; s3, adding an ethanol solution into the concentrated solution, standing, and collecting a precipitate; and S4, volatilizing the ethanol in the precipitate, re-dissolving, taking the supernatant, and drying to obtain the product. By optimizing the extraction and purification process, the dark brown pigment with high extraction rate and high color value is successfully prepared, the dark brown pigment shows excellent stability in a wide pH range and under the conditions of high temperature and high pressure, and the pigment obtained by the invention can be used as a natural brown coloring agent with excellent performance, is widely applied to the field of acid beverages, and has wide application prospects. Meanwhile, an effective way is provided for high-value utilization of dark tea resources.

Devices, systems, and methods for measuring properties of liquids or surrounding gasses within a sealed container. Some embodiments of the devices, systems, and methods disclosed herein are useful for determining and monitoring alcohol (ethanol) content of a liquid within a sealed container. Some embodiments are also useful for determining and monitoring additional properties of the liquid within the sealed container, such as liquid depth (volume) and / or presence of trace chemicals and flavor components.

The present application belongs to the technical field of silica sol preparation, and particularly relates to a silica sol preparation method using ion exchange method. In the prior art, the silica sol growth time is shortened by optimizing the preparation and impurity removal process, and the silica sol seed mother liquor is prepared under ultrasonic assistance. The organic alkali catalyst maintains the silica sol growth pH and the metal ions in the complex solution, so that the impurities are reduced during the silica sol growth. After the introduction of dodecyltrimethoxysilane, hexadecyltrimethoxysilane and methyltrimethoxysilane as the hydrophobic group surface modification, the impurity metal ions are filtered through the complexing agent and the ammonium type resin. The three ethylene tetramine ethanol solution modifies the ammonium type resin, enhances the selective adsorption of the resin to the metal ions, and the maleic anhydride crosslinking agent and nano silicon dioxide modify the ammonium type resin, increase the service life of the ammonium type resin. The prepared silica sol has high purity, good mechanical properties and dispersibility, and excellent hydrophobic performance.

The invention relates to the technical field of electroluminescent materials and devices, in particular to an alcohol-soluble host material for a carbon dot electroluminescent device as well as a preparation method and application of the alcohol-soluble host material. The alcohol-soluble host material for the carbon dot electroluminescent device has a structure as shown in a formula I. According to the invention, phosphate ester is introduced into the alcohol-soluble host material as a side chain, so that on one hand, the solubility of the host material in ethanol can be effectively improved, and on the other hand, the film-forming ability of the host material can be effectively improved. Diphenylamine, carbazole and carbazole derivatives are used as donors, triazine is used as an acceptor, and the host material can be endowed with the characteristic of bipolar transmission. Test results show that the alcohol-soluble host material provided by the invention has excellent alcohol solubility and film-forming ability comparable to that of a polymer host material, and also has good hole and electron transport ability, so that carrier transport is effectively balanced, and the luminous efficiency of a host-guest doped electroluminescent device is improved.

The invention discloses a photocatalytic synthesis method of diethyl disulfide, and relates to the technical field of organic synthesis. The preparation method specifically comprises the following steps: mixing Co (NO3) 2.6 H2O and Ni (NO3) 2.6 H2O, and adding methanol to obtain a solution A; 2-methylimidazole and methyl alcohol are mixed, and a solution B is obtained; mixing the solution A and the solution B to obtain a zeolite imidazole framework material; selenium powder and the zeolite imidazole framework material are mixed and calcined, and a NiCoSe2 material is obtained; the preparation method comprises the following steps: mixing a NiCoSe2 material, ZnCl2, InCl3 and C2H5NS, adding an ethanol water solution, and carrying out microwave hydrothermal synthesis to obtain a NiCoSe2-coated ZnIn2S4 photocatalyst; the NiCoSe2-coated ZnIn2S4 photocatalyst and ethanethiol are subjected to a photocatalytic reaction under N2 atmosphere protection and visible light irradiation, and diethyl disulfide and hydrogen are generated. The method is mild in reaction condition and high in product stability.

The invention relates to a method for continuously synthesizing methyl trifluoroethyl carbonate through three-stage series connection, which comprises the following steps of: reacting dimethyl carbonate and chlorine in the presence of an activated carbon loaded ferric trichloride catalyst, introducing into a gas-liquid separator after the reaction is ended, separating to obtain reaction feed liquid a and unreacted chlorine, and returning the unreacted chlorine to continue the reaction; sufficiently mixing a 50wt% sodium hydroxide solution, trifluoroethanol and the reaction material liquid a, and then carrying out constant-temperature reaction to obtain a reaction material liquid b; methanol and the reaction feed liquid b are fully mixed for a reaction, after the reaction is finished, a reaction product is taken out, a lower-layer methyl trifluoroethyl carbonate crude product is obtained through separation and then rectified and purified in a rectifying tower, and finally high-purity methyl trifluoroethyl carbonate is obtained. Through the design of the micro-channel reactor and the gas-liquid separator, use and recovery of chlorine are effectively controlled, and the safety risk is reduced; meanwhile, the separation cost is low, the energy consumption is reduced, and the high-purity methyl trifluoroethyl carbonate is obtained.

The invention discloses saccharomyces cerevisiae XJ-YSSCE010-1 with high temperature resistance, high ethanol yield and low fusel oil yield and application of the saccharomyces cerevisiae XJ-YSSCE010-1, and belongs to the technical field of microbial fermentation. The saccharomyces cerevisiae XJ-YSSCE010-1 disclosed by the invention is separated and screened from Maotai-flavor liquor yeast, and is preserved in the China General Microbiological Culture Collection Center (CGMCC), and the preservation number is CGMCC No.31174. The fusel oil comprises the following main components: n-propanol, isobutanol, isoamyl alcohol, phenethyl alcohol and the like, wherein isobutanol and isoamyl alcohol have the highest toxicity. The saccharomyces cerevisiae XJ-YSSCE010-1 disclosed by the invention shows the advantages of high yield of ethanol, low yield of fusel oil and no production of isobutanol and isoamyl alcohol in liquid fermentation and simulated high-temperature stacking fermentation experiments, and the saccharomyces cerevisiae XJ-YSSCE010-1 is applied to preparation of white spirit, so that the production efficiency of the white spirit is improved, and the quality of the white spirit is improved.

The present invention produces fermented kombucha beverages with reduced alcohol content by utilizing allulose or analogues thereof as the primary fermentable sugar. These rare sugars limit ethanol production during fermentation while preserving flavor, probiotic benefits, and acidity. The invention further encompasses the incorporation of Kratom (Mitragyna speciosa) extracts or alkaloids into the fermentation process or final product, enabling a low-alcohol kombucha with potential enhanced wellness properties. The resulting beverage maintains an alcohol content below 0.5% by volume, making it suitable for non-alcoholic labeling and broader consumer appeal. The invention is preferably a bottled beverage.

The invention provides a preparation method of clindamycin hydrochloride alcoholate. The preparation method comprises the following steps: firstly, preparing a chlorination reagent from an oily solvent, DMF (Dimethyl Formamide), a chlorination solvent and an antioxidant; carrying out temperature-controlled chlorination reaction with lincomycin hydrochloride to obtain a chlorination reaction solution; adjusting the pH value of the reaction solution to 10-11, controlling the temperature to react, taking an oil phase after the reaction is finished, concentrating under reduced pressure, diluting with water, and adjusting the pH value to 3-5 to obtain a column loading solution; the preparation method comprises the following steps: dissolving clindamycin hydrochloride in water, adsorbing by using resin, eluting impurities by using dilute alkaline water, analyzing by using ethanol and deionized water in sequence, collecting an analysis solution, concentrating under reduced pressure, adding ethanol, heating for dissolving, adjusting the pH value to 1-1.5, cooling for crystallizing, and drying to obtain the clindamycin hydrochloride alcoholate. According to the preparation method disclosed by the invention, the clindamycin alcoholate with high yield and high purity is prepared by pertinently designing processes such as reaction conditions, a specific oily reagent, temperature control conditions, column adsorption, dilute alkaline water impurity elution, ethanol desorption and the like, only one-time crystallization is needed, repeated refining is not needed, the HPLC (High Performance Liquid Chromatography) purity is up to 99.5% or above, and the clindamycin alcoholate is suitable for industrial production. And 0.14% or less of 2, 7-epiclindamycin.

The application relates to the field of CO2 utilization and storage technology, and discloses a double Mannich base corrosion inhibitor as well as a preparation method and application thereof. The method is carried out under the condition that the pH is 3-4; the method comprises the following steps: (1) in the presence of ethanol, a compound shown in formula (A) is subjected to a first reaction with 1,3,5-trioxane to obtain an intermediate product; in formula (A), R is -(CH2)7CH=CH(CH2)7CH3; (2) in the presence of ethanol, the acetophenone is added dropwise into the intermediate product to carry out a second reaction, so that the double Mannich base corrosion inhibitor is obtained; the dropwise speed of the acetophenone is 0.0125-0.05 mL / s relative to 1 mol of the compound shown in formula (A); wherein the molar ratio of the compound shown in formula (A), the acetophenone and the 1,3,5-trioxane is 1:2.0-2.3:2.0-2.3. Formula (A).

The invention belongs to the technical field of organic synthesis. The invention particularly relates to a synthesis method of chiral beta-diaryl ethanol. The physiological activity, the pharmacological action and the material performance of the chiral molecule are directly determined by the spatial configuration of the chiral molecule. Therefore, efficient construction of chiral compounds is always the core research direction of organic synthesis and medicinal chemistry. Wherein the chiral beta-diaryl ethanol is a kind of key intermediates with irreplaceable application value. According to the invention, the Suzuki-Miyaura type asymmetric ring-opening coupling reaction of nickel catalyzed aryl epoxy and aryl boric acid with high stereoselectivity is realized, and the asymmetric ring-opening coupling reaction is used for synthesizing chiral beta-diaryl alcohol compounds. The method is wide in substrate compatibility and raw material source, mild in reaction condition, free of exogenous alkali and convenient to operate. An aryl epoxy compound and arylboronic acid are used as raw materials, diethylene glycol dimethyl ether nickel bromide is used as a catalyst, chiral biimidazoline is used as a ligand, under the promotion of sodium iodide, reaction is performed in an ethanol solvent according to the following reaction formula at the temperature of 50 DEG C for 10 hours, and the chiral beta-diaryl ethanol compound with the high ee value is obtained.

The invention discloses a Pt-coated ZrO2-coated SiO2 catalytic ceramic membrane with a core-shell structure as well as a preparation method and application of the Pt-coated ZrO2-coated SiO2 catalytic ceramic membrane, and belongs to the technical field of advanced oxidation and water treatment. The method comprises the following steps: preparing platinum nano sol by an ethylene glycol reduction method; the preparation method comprises the following steps: coating Pt-coated ZrO2 core-shell particles with tetragonal phase ZrO2; the preparation method comprises the following steps: preparing a porous SiO2 shell, dispersing the porous SiO2 shell in an ethanol solution, adding tetraethoxysilane (TEOS), coating the porous SiO2 shell through a Stber method by taking cetyltrimethylammonium bromide (CTAB) as a template agent and ammonia water as a catalyst, and then roasting to remove the template agent to form Pt-coated ZrO2-coated SiO2 core-shell particles; the preparation method comprises the following steps: uniformly dispersing Pt-coated ZrO2-coated SiO2 core-shell particles in absolute ethyl alcohol to obtain a suspension, dipping a commercial alpha-Al2O3 flat sheet membrane in the suspension, taking out, drying, and sintering in an air atmosphere to obtain the Pt-coated ZrO2-coated SiO2 catalytic ceramic membrane with the core-shell structure. The ceramic membrane is high in catalytic activity, good in stability and large in membrane flux. The invention is applied to advanced treatment of algae-containing water and degradation-resistant organic wastewater.