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4336 results about "Ethyl group" patented technology

In chemistry, an ethyl group is an alkyl substituent derived from ethane (C₂H₆). It has the formula –CH₂CH₃ and is very often abbreviated Et. Ethyl is used in the IUPAC nomenclature of organic chemistry for a saturated two-carbon moiety in a molecule, while the prefix "eth-" is used to indicate the presence of two carbon atoms in the molecule.

Polymer additive and application thereof

The invention provides a polymer additive and application thereof. The polymer additive is prepared from the following components in parts by mass: 30 to 90 parts of diethyl phosphinate, 0.01 to 3 parts of ethyl phosphonate, 5 to 67 parts of dialkyl phosphinate and 0.01 to 5.5 parts of alkyl phosphinate. The dialkyl phosphinate has a structure as shown in a formula I, and the alkyl phosphinate has a structure as shown in a formula II. According to the invention, through design and compounding synergy of various phosphonates, the flame-retardant effect can be obviously improved, so that the polymer additive has excellent and efficient flame retardance. The polymer additive is used in a polymer material, and a polymer composition containing the polymer additive can have excellent flame retardant property, good toughness, high impact strength and excellent mechanical property and humidity and heat resistance under the condition that the addition amount is small.
Owner:SHANGHAI KINGFA SCI & TECH +2

Process for the preparation of (2-(3,6-dimethoxy-9H-carbazol-9-yl)ethyl)phosphonic acid

The application provides a process method for preparing (2-(3,6-dimethoxy-9H-carbazol-9-yl)ethyl) phosphonic acid, and particularly relates to the technical field of organic synthesis. The process method is that, under alkaline conditions, a halogenated phosphonate compound is added into a 3,6-dimethoxy-9H-carbazole solution to perform a reaction, hydrochloric acid aqueous solution is added after the reaction to perform acidolysis degreasing, and finally (2-(3,6-dimethoxy-9H-carbazol-9-yl)ethyl) phosphonic acid is obtained through extraction, reflux adsorption and beating purification. The process method uses 3,6-dimethoxy-9H-carbazole as a starting material, realizes the synthesis of the target product through one-pot reaction, has mild reaction conditions, uses non-toxic raw materials which are easy to obtain, has simple synthesis process, is convenient to operate, and has high separation yield.
Owner:DAGAO IND TECH RES INST (GUANGZHOU) CO LTD

Salt-responsive temperature-resistant salt-resistant tackifying filtrate reducer for water-based drilling fluid as well as preparation method and application of tackifying filtrate reducer

The invention provides a salt-responsive temperature-resistant salt-resistant water-based drilling fluid tackifying filtrate reducer as well as a preparation method and application thereof, and belongs to the technical field of drilling. The tackifying filtrate reducer is prepared from the following raw materials in parts by mass: 30 to 50 parts of 1-(2-carboxyethyl)-2-vinylpyridine, 20 to 40 parts of (3-(methacrylamido) propyl) dimethyl (3-thiopropyl) ammonium hydroxide inner salt, 35 to 55 parts of N, N-dimethylacrylamide, 10 to 25 parts of 4-vinylpyridine, 300 to 500 parts of water and 1 to 5 parts of an initiator. According to the filtrate reducer, cations and anions are concentrated on one monomer molecule, so that the synthesized product contains the cations and the anions with the same charge number, has good adsorption capacity and salt response characteristics, is compatible with salt essentially, can effectively resist high temperature and high salt, and can be recycled. And the viscosity-increasing and filtrate-reducing agent has good viscosity-increasing and filtrate-reducing effects on the drilling fluid.
Owner:XI'AN PETROLEUM UNIVERSITY

Organic amine composite absorbent for carbon capture and application thereof

The invention discloses an organic amine composite absorbent for carbon capture and application thereof, and belongs to the technical field of carbon dioxide capture, the organic amine composite absorbent for carbon capture is in a solution state and comprises the following components: a main agent, an auxiliary agent, an accelerant A, an accelerant B and water; wherein the mass ratio of the main agent to the auxiliary agent is 2: (1-2); the mass ratio of the auxiliary agent to the accelerant A is 2: (1-2); the mass ratio of the accelerant A to the accelerant B is 2: (1-2); the total mass concentration of the main agent, the auxiliary agent, the accelerant A and the accelerant B in the organic amine composite absorbent for carbon capture is 30-40 wt%; the main agent is selected from N-methyldiethanolamine or N, N-diethyl ethanolamine, the auxiliary agent is selected from piperazine or hydroxyethyl ethylenediamine, the accelerant A is selected from triethylene glycol monomethyl ether and / or ethylene glycol monomethyl ether, and the accelerant B is selected from ethyl butyl ether and / or isobutyl ether. The organic amine composite absorbent for carbon capture has a wide application prospect in removal of carbon dioxide in flue gas.
Owner:ZHEJIANG UNIV +1

Chemical grafting modified polypropylene capacitor film material as well as preparation method and application thereof

The invention belongs to the technical field of thin film capacitors, and particularly relates to a chemical grafting modified polypropylene capacitor film material and a preparation method and application thereof. According to the preparation method of the chemical grafting modified polypropylene capacitor film material, provided by the invention, diethylenetriamine ethyl acrylate with a plurality of specific groups such as amino groups and carboxyl groups and unsaturated double bonds is synthesized through esterification reaction, and the diethylenetriamine ethyl acrylate is introduced into a polypropylene material through chemical grafting to obtain chemical grafting modified polypropylene; the prepared polypropylene capacitor film material has the excellent properties of good compatibility, difficulty in film breakage, capability of adsorbing and removing residual moisture, difficulty in oxidation corrosion, excellent breakdown resistance and the like, and the preparation method is a preparation method of the high-performance polypropylene capacitor film material; therefore, the technical problem that a polypropylene capacitor film material prepared in the prior art is low in performance is solved.
Owner:ELECTRIC POWER RES INST CHINA SOUTHERN POWER GRID CO LTD

Whitening and freckle-removing composition, gel, preparation method therefor, and use thereof

Provided are a whitening and freckle-removing composition, a gel, a preparation method therefor, and a use thereof, relating to the technical field of skin-care products. The whitening and freckle-removing composition comprises tranexamic acid, nicotinamide, 4-butylresorcinol, licorice extract, 3-o-ethyl ascorbic acid, and glutathione. For the whitening composition, by inhibiting the activity of tyrosinase, blocking the transfer of melanin from melanocytes to keratinocytes, and inhibiting the formation and accumulation of melanin by means of multiple mechanisms including oxidation resistance, and by means of the synergistic action of all components, cosmetic benefits of whitening and freckle-removing are achieved. The whitening and freckle-removing gel has a simple preparation method, has a mild and non-sensitizing formula, is safe and non-irritating, and is suitable for large-scale production and application.
Owner:BEIJING CAS MICRONEEDLE TECH LTD +1

Flame-retardant ABS (Acrylonitrile Butadiene Styrene) composition and preparation method and application thereof

PendingCN121895709APolymer sciencePhosphate
The invention discloses a flame-retardant ABS (Acrylonitrile Butadiene Styrene) composition as well as a preparation method and application thereof, and relates to the technical field of high polymer materials. The flame-retardant ABS composition provided by the invention comprises the following components in parts by mass: 50-80 parts of ABS resin; 8 to 12 parts of styrene-acrylonitrile copolymer; 3 to 5 parts of styrene-acrylonitrile-maleic anhydride terpolymer; 2 to 6 parts of a fluorine-containing maleimide copolymer; 5 to 15 parts of graphite nanosheet modified high rubber powder; 12 to 18 parts of brominated flame retardant; 3-7 parts of a phosphorus-based flame retardant; 0.1-1 part of a processing aid; the phosphorus-based flame retardant is prepared from the following components in parts by mass: 80 to 95 parts of diethyl phosphinate; 0.3 to 3 parts of ethyl butyl phosphinate; 0.1 to 2 parts of ethyl phosphonate; and 5 to 20 parts of melamine polyphosphate. The flame-retardant ABS composition prepared by the invention is good in flame retardant property, good in welding strength and low in cost.
Owner:GUANGDONG XINDA ADVANCED MATERIALS TECH CO LTD +1

Efficient wet desulphurization synergist and preparation method thereof

The invention discloses an efficient wet desulfurization synergist and a preparation method thereof, and relates to the technical field of flue gas desulfurization. The efficient wet desulphurization synergist comprises the following raw materials in parts by weight: 10-20 parts of sodium formate, 5-10 parts of citric acid, 20-30 parts of binary acid, 5-6 parts of a surfactant, 15-20 parts of magnesium salt, 12-18 parts of sodium salt and 2-5 parts of a pH buffer agent. The preparation method comprises the following steps: reacting cyanuric chloride with lauryl amine to generate a monosubstituted compound; then reacting with L-asparaginic acid to generate a disubstituted compound; reacting with diethylenetriamine to generate a bis-triazine ring compound; and finally, reacting with sodium 2-chloroethanesulfonate to generate the surfactant. The high-efficiency wet desulphurization synergist prepared by the invention has a desulphurization effect.
Owner:SHANDONG KAIMIKE CHEM CO LTD

Preparation method of second-generation denitrified flavin TND1128

The invention discloses a preparation method of second-generation denitrified flavin TND1128, which comprises the following steps: S1, by taking 1-methylbarbituric acid and o-aminobenzaldehyde as raw materials and a mixture of water and alcohol as a solvent, heating and reacting to generate an intermediate I; s2, taking the intermediate I as a raw material, and performing ethylation under the combined action of inorganic alkali and an ethylation reagent to generate a TND1128 crude product; s3, the TND1128 crude product is purified, and a TND1128 pure product is obtained; according to the invention, 1-methylbarbituric acid and 2-nitrobenzaldehyde are taken as raw materials for cyclization synthesis of an intermediate I, then ethylation and pulping purification are carried out under the combined action of inorganic base and an ethylation reagent, and high-purity TND1128 is synthesized in a high-yield, high-specificity and high-selectivity manner; the method has the advantages of simple process route, good reaction selectivity, high yield, cheap and easily available raw materials, low equipment requirement, easy realization of industrial production and the like.
Owner:苏州满元生物科技有限公司

Preparation method of cell inflammatory factor adsorbent

The invention discloses a preparation method of a cell inflammatory factor adsorbent, which comprises the following steps: mixing styrene, divinyl benzene and hydroxyethyl acrylate, and adding a pore-foaming agent and mesoporous SiO2 nano powder to prepare a porous microsphere carrier; the preparation method comprises the following steps: mixing chitosan and poly (N-isopropylacrylamide) in an acetic acid solution to obtain a temperature-sensitive chitosan hydrogel precursor solution; the preparation method comprises the following steps: activating the surface of a porous microsphere carrier by using 1-ethyl-(3-dimethylaminopropyl) carbodiimide and N-hydroxysuccinimide, mixing the activated porous microsphere carrier and a temperature-sensitive chitosan hydrogel precursor solution to obtain a water phase, and assembling, washing and drying in an oil phase to obtain the cell inflammatory factor adsorbent. Through the design of the core-shell structure and the addition of the mesoporous SiO2 nano powder, the temperature response characteristic and the recyclable characteristic are given to the cell inflammatory factor adsorbent, the adsorption capacity of cell factors is also improved, and a new solution is provided for physical adsorption of the cell inflammatory factors.
Owner:ZHEJIANG ZHONGHUI LIZHI MEDICAL TECHNOLOGY CO LTD

Composite chelating blocking remover for oil field and preparation method of composite chelating blocking remover

The invention belongs to the technical field of preparation of blocking removers, and particularly relates to a composite chelating blocking remover for an oil field and a preparation method of the composite chelating blocking remover. The composite chelating blocking remover for the oil field is prepared from the following raw materials in percentage by mass: 7 to 9 percent of 1-butyl-3-methylimidazole dodecyl sulfonate, 5 to 7 percent of erucamide propyl hydroxypropyl sulfobetaine, 3 to 4 percent of di-(2-ethylhexyl) sodium sulfosuccinate, 4 to 5 percent of ethylenediamine di-o-hydroxyphenylacetic acid, 5 to 7 percent of N, N '-di (2-hydroxybenzyl) ethylenediamine-N, N'-bis (2-hydroxybenzyl)-N, N '-bis (2-ethylhexyl)-N, N'-bis (2-hydroxybenzyl)-N, N '-bis (2-hydroxybenzyl)-N, N'-bis (2-hydroxyphenyl)-N, N '-bis (2-hydroxyphenyl)-N, N'-bis (2-hydroxyphenyl)-N The cleaning agent is prepared from the following components in percentage by weight: 3 to 4 percent of N, N '-diacetic acid, 2 to 3 percent of O-(3-(benzyloxy) propyl) hydroxylamine, 1 to 2 percent of heptadecenyl hydroxyethyl imidazoline quaternary ammonium salt, 1 to 1.5 percent of dimethyl diallyl ammonium chloride homopolymer and the balance of water. The composite chelating blocking remover for the oil field has excellent scale dissolution rate and paraffin inhibition rate when being applied to complex scale blocking removal of the oil field.
Owner:SHENGLI OILFIELD HAIFA ENVIRONMENTAL PROTECTION CHEM CO LTD +1

Polyamide composition and application thereof

The invention provides a polyamide composition and application thereof. The polyamide composition comprises the following components in parts by mass: 40-99.5 parts of polyamide, 10-45 parts of a reinforcing material and 5-35 parts of a flame retardant, the flame retardant is prepared from the following components in parts by mass: 30 to 90 parts of diethyl phosphinate, 0.01 to 3 parts of ethyl phosphonate, 5 to 67 parts of dialkyl phosphinate and 0.01 to 5.5 parts of alkyl phosphinate. According to the invention, by introducing the specific flame retardant, an efficient flame retardant effect can be exerted, so that the polyamide composition has excellent flame retardant property and excellent impact resistance.
Owner:KINGFA SCI & TECH CO LTD +2

Coolant containing organopolysiloxane

To provide a coolant which exhibits relatively excellent fluidity even at low temperatures and can be easily handled and stored due to having a high flash point.SOLUTION: This coolant contains an organopolysiloxane represented by formula (1) (wherein R1 moieties are each independently a methyl group or an ethyl group, and n is 2 or 3), and is characterized in that the organopolysiloxane has a kinematic viscosity of 100 mm2 / s or less at -80°C and 300 mm2 / s or less at -100°C.SELECTED DRAWING: None
Owner:SHIN ETSU CHEMICAL CO LTD

A method for synthesizing elastatin and its intermediates

The present invention provides a method for synthesizing alacastran, comprising reacting an amino compound of formula V with a chiral intermediate of formula VI, reducing the resulting product with a reducing agent capable of providing an ethyl group to produce a compound of formula VII, and then deprotecting the compound to obtain alacastran, as shown in the following reaction formula. The method for synthesizing alacastran of the present invention avoids the low yield caused by amide reduction and the risk of substrate racemization, has a high yield, low material cost, safe operation, and is suitable for industrial production.
Owner:AURISCO PHARM(TIANJIN) INC +1

Sustained-release coating as well as preparation method and application thereof

The invention relates to the technical field of medicines, in particular to a sustained-release coating as well as a preparation method and application thereof. The coating adopts a three-layer gradient structure design and comprises an inner layer coating, a middle layer coating and an outer layer coating, and the layers are compounded and matched through ethyl cellulose and hydroxypropyl methylcellulose with different molecular weights and are combined with talcum powder filling amount with gradient decreasing and a triethyl citrate plasticizer, so that accurate regulation and control of drug release are realized. Through hierarchical swelling-diffusion dynamic balance, burst release is inhibited, the inner layer has high talcum powder content to resist initial swelling stress, the outer layer has low filling amount to maintain hydrophobic continuity, interface defects are reduced in combination with high-temperature curing, and the release stability and long-term storage performance of drugs such as dihydroergoline mesylate are remarkably improved; the problems of sudden release, damp-heat sensitivity, impurity generation and the like of a traditional single-layer coating are solved.
Owner:宝利化(南京)制药有限公司

Special nano-powder coating for anticorrosion of super-long ship, preparation method and application

The application discloses a kind of ship super-long anticorrosion special nano powder coating, preparation method and application, belong to ship heavy anticorrosion material technical field.The preparation method of the ship super-long anticorrosion special nano powder coating is as follows: epoxy resin, graphene modified epoxy resin, core-shell structure ZnO@SiO2, modified 2,5-dimercapto-1,3,4-thiadiazole, borosilicate glass powder, flaky boron nitride, silane coupling agent modified silica, phenolic amine curing agent, 2-ethyl-4-methylimidazole, fumed silica, defoaming agent, ultraviolet absorber, high-temperature pigment are put into stirrer and stirred for 20-30min, then melt extrusion is carried out through double screw extruder, the extrusion temperature is 90-110 DEG C, grinds and sieves, and the ship super-long anticorrosion special nano powder coating is obtained.The coating prepared by the application has good anticorrosion performance and can be applied in the field of ship metal surface corrosion protection.
Owner:GUANGDONG RUIZHI HIGH-TECH CO LTD

Aquatic collagen tripeptide and processing technology thereof

The invention relates to the technical field of collagen peptide extraction, and particularly discloses aquatic collagen tripeptide and a processing technology thereof, and the processing technology comprises the following steps: step S1, fish skin pretreatment; step S2, performing enzymolysis; step S3, fermentation; step S4, separation and purification; starting from three aspects, firstly, a modified degreasing agent is added in the degreasing treatment process, the modified degreasing agent takes 1-ethyl-3-methylimidazole acetate, zinc phytate and calcium citrate as main components according to a specific mass ratio, and secondly, gel emulsion is added in the enzymolysis process, so that the modified degreasing agent is prepared. The gel emulsion has an oil gel structure, grape seed oil and sodium lignin sulfonate, and 3, a composite strain is added in the fermentation process, the composite strain is prepared by mixing bacillus natto and lactobacillus plantarum according to a specific proportion, and the purity and the extraction rate of the aquatic collagen tripeptide are improved through the synergistic effect of all the procedures.
Owner:YANTAI NEW ERA HEALTH IND DAILY CHEM CO LTD

Aggregation-induced emission material, nanoparticle and preparation method and application thereof

The invention relates to the technical field of luminescent materials, and discloses an aggregation-induced emission material, nanoparticles as well as a preparation method and application thereof, the structural general formula of the aggregation-induced emission material is as follows: # imgabs0 #, R is selected from one of the following structures: # imgabs1 # aggregation-induced emission material takes a pyridine group as an acceptor unit, and the acceptor unit is selected from one of the following structures: 1 # imgabs2 # aggregation-induced emission material; a carbon-carbon double bond and a thiophene unit are used as pi bridges, and diphenylamine, bis (4-ethylphenyl) amine and bis (4-(tert-butyl) phenyl) amine are used as strong electron donors. The donors not only provide strong electron supply ability, but also become efficient rotors due to highly twisted molecular conformation, and endow the aggregation-induced emission material with long emission wavelength and aggregation-induced emission activity.
Owner:SHENZHEN UNIV

Preparation method of optical OCA (Optical Clear Adhesive) and application of optical OCA in folding screen of mobile phone

The invention discloses a preparation method of an optical OCA (Optical Clear Adhesive) and application of the optical OCA in a mobile phone folding screen, and relates to the technical field of optical cement, the optical OCA is prepared from the following raw materials in parts by weight: 50 parts of acrylate prepolymers, 2-4 parts of 3-allyl-2-mercapto-3H-quinazoline-4-ketone, 1-3 parts of diallyl disulfide, 1-3 parts of 3-[N, N-dimethyl formamide], 1-3 parts of 2, 3, 5-trimethyl-1, 3-pentanediol monoisobutyronitrile, 1-3 parts of 2, 3, 5-trimethyl-1, 3, 5-trimethyl-1, 3, 5-trimethyl-1, 3 The preparation method comprises the following steps: adding 3-5 parts of N, N-dimethyl-[2-(2-methylpropane-2-enoyloxy) ethyl] ammonium] propane-1-sulfonic acid inner salt, 1-3 parts of allyl succinimido carbonate, 2-4 parts of dicyclopentene methacrylate, 1-3 parts of 1, 3, 5-triacryloyl hexahydro-1, 3, 5-trimethyl-1, 3, 5-trimethyl-1, 3, 5-trimethyl-1, 3, 5-trimethyl-1, 3, 5-trimethyl-1, 3, 5-trimethyl-1, 3, 5-trimethyl-1, 3, 5- The invention relates to a graphene quantum dot photoinitiator which is prepared from the following components in parts by weight: 1-3 parts of 1, 3, 5-triazine, 0.8-1.2 parts of a photoinitiator, 1-3 parts of an aziridine cross-linking agent, 1-3 parts of graphene quantum dots, 0.8-1.2 parts of a coupling agent and 40-50 parts of a diluent. The optical OCA adhesive is high in light transmittance and bonding strength, good in weather resistance and excellent in folding resistance.
Owner:DONGGUAN HANGDA ELECTRONICS

Phosphate-based fire-resistant oil with synergistically optimized flame resistance and stability and preparation method of phosphate-based fire-resistant oil

The invention relates to the field of fire-resistant oil, in particular to phosphate-based fire-resistant oil with synergistically optimized flame resistance and stability and a preparation method of the phosphate-based fire-resistant oil. The fire-resistant oil comprises base oil and an additive, the base oil is a mixture obtained by esterification of mixed alkylphenol and phosphorus oxychloride; the molar percentage of the mixed alkylphenol is as follows: 4-6% of phenol; 11 to 14 percent of p-methylphenol; 22 to 26 percent of 2, 5-position dimethyl phenol; 0.8 to 1.5 percent of 2, 4-position dimethyl phenol; 2.5 to 4 percent of 2, 3-position dimethyl phenol; 0.4 to 0.6 percent of 4-ethyl phenol; 40 to 48 percent of 3, 5-position dimethyl phenol; 8 to 11% of 3-ethyl phenol; 3 to 5 percent of 3, 4-position dimethyl phenol; the additives comprise an antioxidant, a corrosion inhibitor, an anti-foaming agent and an anti-hydrolysis agent; the addition amount of the antioxidant is 0.05-5% of the total mass of the base oil; the addition amount of the corrosion inhibitor is 0.001%-0.08% of the total mass of the base oil; the addition amount of the anti-foaming agent is 0.001%-0.009% of the total mass of the base oil; the addition amount of the anti-hydrolysis agent is 0.001%-0.005% of the total mass of the base oil. The fire-resistant oil provided by the invention can be safely used under the working conditions of high temperature and extreme pressure.
Owner:JIANGSU NUCLEAR POWER CORP

Aminoethanesulfonic acid type surfactant as well as preparation method and application thereof

The invention relates to the technical field of oilfield chemistry, in particular to an aminoethanesulfonic acid type surfactant and a preparation method and application thereof.The preparation method of the aminoethanesulfonic acid type surfactant comprises the steps that firstly, fatty amine is dissolved in a first solvent, a sodium chloroethanesulfonate aqueous solution is added, and N-long-chain alkyl-2-sodium aminoethanesulfonate is obtained through a reaction; and 2, dissolving a required amount of N-long-chain alkyl-2-sodium aminoethanesulfonate in a second solvent, adding a required amount of methyl acrylate, and reacting to obtain the aminoethanesulfonic acid type surfactant. The aminoethanesulfonic acid type surfactant disclosed by the invention contains long-chain alkyl, amino, ester groups and sulfonic acid groups, so that the aminoethanesulfonic acid type surfactant has good surface activity and can meet the development requirements of oil and gas fields. The microemulsion cleanup additive prepared from the aminoethanesulfonic acid type surfactant can effectively reduce the surface tension and the interfacial tension of an aqueous solution, and the preparation method is easy and convenient to operate, mild in condition and suitable for industrial production.
Owner:CHINA NAT PETROLEUM CORP +1

Biomass-inorganic-organic ternary composite flocculant as well as preparation method and application thereof

The invention discloses a biomass-inorganic-organic ternary composite flocculant and a preparation method and application thereof, and belongs to the field of coking wastewater treatment.The preparation method comprises the steps that chitosan serves as a substrate material, glutaraldehyde serves as a cross-linking agent, and polyferric sulfate (PFS) and chitosan are subjected to chemical cross-linking to generate an intermediate product PFS and chitosan composite particles; then potassium persulfate is used as an initiator, graft copolymerization of acrylamide and methacryloyloxyethyl trimethyl ammonium chloride is initiated through hydroxyl on the surface of PFS-chitosan, a cationic branched chain is introduced, and a final product is obtained. Through multi-component cooperation and structural design, the defects that a traditional flocculating agent is not thorough in demulsification, large in sludge amount, unstable in floc combination and the like in coking wastewater treatment are overcome, and the flocculating agent is particularly suitable for treating oil pollutants in coking wastewater.
Owner:NANJING UNIV

Alpha methyl beta phosphonate compound and synthesis method thereof

The invention relates to the technical field of chemical synthesis, and particularly discloses an alpha methyl beta phosphonate compound and a synthesis method thereof.The alpha methyl beta phosphonate compound is obtained by directly oxidizing the alpha position of aryl ketone into carbon positive and combining the carbon positive with diethyl phosphite anions under the alkaline condition by using hydrogen peroxide and iodine as oxidizing agents. The alpha methyl substituted beta phosphate ester compound can be generated by a one-step method. The method is suitable for synthesizing compounds of phosphoric acid (methyl, ethyl, propyl and the like) with different alkyl substitutes (methyl, ethyl, propyl and the like) at carbonyl alpha positions. According to the method, the alpha-methyl substituted beta phosphate compound can be synthesized only by using commercial cheap and easily available aryl ketone as a raw material, using hydrogen peroxide and iodine as oxidants and using diethyl hypophosphite as a phosphine source, and reacting in the DMSO solvent at 100 DEG C for 12 hours, so that the target product can be obtained, and the yield is excellent. Compared with previously reported methods, the method does not need low-temperature operation, is simple to operate, adopts a one-pot method, does not need a metal catalyst, and all raw materials are common bulk chemicals.
Owner:QUZHOU RES INST OF ZHEJIANG UNIV

Solid form of 4-[3-(cyclopropylmethoxy)-4-(difluoromethoxy)phenethyl]pyridine-2(1H)-one and preparation method therefor

The present application relates to a crystal form of 4-[3-(cyclopropylmethoxy)-4-(difluoromethoxy)phenethyl]pyridine-2(1H)-one, a preparation method therefor, a composition containing the crystal form and the use thereof in the treatment of phosphodiesterase-related diseases.
Owner:BEIJING TIDE PHARMACEUTICAL CO LTD

Purpurine-anthraquinone composite electrochromic liquid and preparation method thereof

The invention relates to viologen-anthraquinone composite electrochromic liquid and a preparation method thereof, the viologen-anthraquinone composite electrochromic liquid comprises 1.2-2.5 parts by mole of viologen salt, 0.8-1.5 parts by mole of anthraquinone derivative and 8-12 parts by mole of electrolyte; the viologen salt is ethyl viologen tetrafluoroborate or heptyl viologen tetrafluoroborate or octyl viologen tetrafluoroborate; the anthraquinone derivative is 1-ethylamino-4-hydroxy anthraquinone or acid blue 43; the preparation method comprises the following steps: preparing an electrolyte solution; adding purple refined salt and anthraquinone derivatives according to the formula; fully dissolving the electrochromic material to form uniform and transparent initial liquid; and degassing the initial liquid to remove oxygen dissolved in the initial liquid. The electrochromic liquid has the advantages that after the purple refined salt and the anthraquinone derivative are added into the dissolving solution according to the proportion of the formula, the two color-changing materials are jointly dissolved in the electrolyte, and when the two color-changing materials are reduced at the same time, spectrum superposition absorbed by the two color-changing materials can cover the whole visible region, so that black and white switching of the electrochromic liquid is realized, and the use effect is good.
Owner:YANGZHOU JINGCAI OPTOELECTRONICS TECH CO LTD