43 results about "Triketone" patented technology

A geopolymer precursor includes an alkaline reactive solid material containing aluminum, silicon, and oxygen, and a fluid loss control material having an ionic stability property that has a first value in water and a second value in a 3M solution of NaOH, wherein a ratio of the second value to the first value is in a range of 0.5 to 2.0. The fluid loss control material may be, or may include a crosslinked polymer, which may include a reaction product of one or more of acrylamide, 2-acrylamido-2-methyl propane sulfonic acid, N,N‑dimethylacrylamide, N,N‑diethylacrylamide, vinyl acetate, or another monomer, and a crosslinker including one or more of methylene bisacrylamide, triallyl amine, pentaerythritol allyl ether, triallyl-triazine-trione, or another material. The geopolymer precursor may include an activator, an alkaline solution having pH of at least about 9, or both.

The present application relates to the technical field of materials, in particular to a multi-stage solidification shape memory polymer for 4D printing and a preparation method thereof. In view of the problem that it is difficult to build gradient mechanical functions by precisely regulating the structure modulus in a single structure of 4D printing, the present application obtains a single-component multi-stage solidification shape memory polymer by regulating the ratio of toluene-2, 4-diisocyanate-hydroxypropyl acrylate, shape memory polymer, polyethylene glycol 400 and 1, 3, 5-tris (6-isocyanate hexyl) -1, 3, 5-triazine-2, 4, 6-trione under the test feedback of the printing structure modulus, and solves the problem that it is difficult to build gradient mechanical properties in a single structure of 4D printing.

The present disclosure relates to a herbicidal combination comprising a carbamate herbicide and a triketone herbicide.

The invention provides a synthesis method and application of a tetra-substituted pyran compound. The tetra-substituted pyran compound is directly constructed through a one-pot cascade reaction under an organic base catalysis system by taking triketone olefin and allyl ammonium salt as key reaction raw materials. The method has the advantages that the operation is simple and convenient, no water or oxygen is needed, the reaction is efficient, the steps are simple, the method is environment-friendly, the reaction is easy to amplify, and the method has practical value. Activity tests prove that the compounds have certain inhibitory activity on alpha-glucosidase, or can be used for treating diabetes mellitus.

An object of the present invention is to provide a resin composition that has excellent impregnability into fibers, enables favorable continuous production of a prepreg, and enables production of a prepreg that enables favorable production of a molded article.SOLUTION: A three dimensional crosslinked structure in which a compound (A) having two or more acetoacetic acid ester groups, aldehyde groups, or triketone structures alone or in combination in a molecule and an amine compound (B) having two or more primary amino groups in a molecule are bonded to each other, and a ketimine compound (D) in which at least one primary amino group of the amine compound (B) and a ketone group of the ketone compound (C) are condensation-bonded, wherein among the primary amino groups of the amine compound (B) constituting the ketimine compound (D), a proportion of the primary amino groups bonded to the ketone compound (C) is 1kPa% or more, the ketone compound (C) having a steam pressure at 20 °C of 0. 50mol or more.SELECTED DRAWING: None

The application provides a pyridinone compound and a preparation method and application thereof, and belongs to the technical field of compound synthesis.The pyridinone compound is (E)-5-[(hydroxyl methylene)amino]-1,2,3,6-tetrahydropyridine-2,3,6-trione, and the molecular formula is C6H4N2O4.The pyridinone compound of the application simultaneously contains a hydroxyl group, an imino group and multiple carbonyl functional groups in the structure, forms a unique conjugated system and hydrogen bond network, and has the potential to be used as a bioactive precursor or a functional material.The pyridinone compound with a purity greater than 95% and a yield greater than 94% can be obtained by using the preparation method of the application, the compound shows good performance in dyeing applications, not only expands the application range of the pyridinone compound, but also provides a new way for realizing high-value utilization of fermentation broth resources, and has the advantages of environmental protection and economic benefits.

The invention relates to the technical field of organic synthesis of steroid compounds, in particular to a preparation method of androstane-4-ene-3, 6, 17-triketone. Dehydroepiandrosterone acetate is used as an initial raw material to prepare androstane-4-ene-3, 6, 17-triketone through four steps of reactions including chlorohydrination, hydrolysis, oxidation and elimination, the yield and purity of androstane-4-ene-3, 6, 17-triketone are improved, 4-AD impurities are not generated, the total yield of a route reaches 80%, and the purity is larger than or equal to 98.0%; and the preparation process does not involve the use of dangerous chemicals and environment-polluting chromium oxidants, and is suitable for industrial production.

The invention discloses a preparation method of 1, 3-diallyl-5-ethylene oxide methyl-[1, 3, 5] triazine-2, 4, 6-triketone, sodium isocyanurate, chloropropene and epoxy bromopropane are used as raw materials, and a product is synthesized through two-step reaction: S1, preparation of intermediates: the sodium isocyanurate and the chloropropene are subjected to a reaction in a polar aprotic organic solvent, the reaction is carried out for 2-4 hours, and the product is obtained; carrying out a first-step reaction under the action of a catalyst and a cocatalyst, filtering, evaporating the solvent to dryness, and purifying to obtain an intermediate diallyl isocyanurate; s2, preparation of a target product: in a polar aprotic organic solvent, carrying out a second-step reaction on the intermediate and epoxy bromopropane under the action of an acid capturing agent, carrying out rotary evaporation to remove the solvent, washing and drying, and purifying to obtain the target product, a plurality of aspects such as a catalyst and a reaction system are researched, the reaction temperature is reduced, and a product with the purity conforming to the application in the field of electronic chemistry is obtained.

The invention relates to control of resistant pests. In particular, the present invention relates to a method of controlling an insecticide-resistant pest comprising exposing the insecticide-resistant pest to a pest control amount of a triketone compound.

The application discloses a new use of androsta-4,6,8(9),13(14)-tetraen-3,11,16-trione, namely, application of the androsta-4,6,8(9),13(14)-tetraen-3,11,16-trione in preparation of a medicine for treating lymphoma. 50 The IC value of the androsta-4,6,8(9),13(14)-tetraen-3,11,16-trione in the SR cell line is detected by a CCK-8 method, and the cytotoxicity of the androsta-4,6,8(9),13(14)-tetraen-3,11,16-trione on human umbilical vein endothelial cells Huvce and human immortalized keratinocytes Hacat is detected, in the body, the androsta-4,6,8(9),13(14)-tetraen-3,11,16-trione significantly inhibits tumor growth and shows good biological safety and no systemic toxicity; TUNEL staining, gamma-H2AX staining and neutral comet experiment prove that the compound of the application inhibits the growth of SR by causing serious damage to DNA, the application not only adds the diversity of the biological activity of the androsta-4,6,8(9),13(14)-tetraen-3,11,16-trione, but also provides a new direction for developing a new medicine for treating lymphoma.

The application discloses a kind of heat-insulating fireproof materials and preparation method thereof, from top to bottom sequentially include first encapsulation layer, first fireproof support layer, first viscose layer, heat-insulating layer, second viscose layer, second fireproof support layer and second encapsulation layer;The first viscose layer, second viscose layer are independently made of the following raw materials respectively: amino-terminated hyperbranched polyimide, acrylic modified poly (ether ether ketone), 1,3-bis (oxymethylene methyl) -5- (2-propenyl) -1,3,5-triazine-2,4,6 (1H,3H,5H) -trione, 1,1,3,3-tetramethyl-1,3-divinyl disilazane, 3- (1,1-difluoro-2-propylene-1-yl) -2 (1H) -quinoxaline ketone, 2- (1-propylene-2-yl) benzo [d] oxazole, terpene resin, initiator, solvent.The material heat-insulating fireproof effect is remarkable, and mechanical mechanical property and high temperature resistance are sufficient.

The present invention relates to aqueous dispersions comprising an ALS inhibitor, typically a sulfonylurea herbicide, specifically from the class of triazolinones herbicides, a HPPD inhibitor, specifically a triketone as from the class of 2-benzoyl-1,3-cyclohexanedione herbicides, optionally a safener from the class of the sulfonamides, a water-soluble herbicide present as a salt, specifically glyphosate and to dispersions resulting from dispersing the concentrate suspension in water, to a method of making the aqueous suspension and to a method of controlling unwanted plants using these dispersions.

The invention belongs to the technical field of organic synthesis, and particularly discloses a terpyridine derivative synthesis method, which comprises: carrying out a hydrolysis / carboxylation reaction on a 2-cyanopyridine derivative under the catalysis of an acidifying agent, the method comprises the following steps: adding a catalyst into a pyridine-2-carboxylic acid derivative in an aprotic polar solvent, and carrying out intermolecular condensation cyclization on the pyridine-2-carboxylic acid derivative; the preparation method comprises the following steps: in the presence of an ammonium salt, constructing a terpyridine skeleton through a dehydration ring-closing reaction of a 1, 5-di (2-pyridyl) pentane-1, 3, 5-triketone derivative; a chlorination reagent is adopted to carry out selective chlorination reaction on a terpyridyl skeleton. According to the synthesis method of the terpyridyl derivative, the economical efficiency, the safety, the environmental protection property and the industrial feasibility are considered, a new path is provided for efficient, green and low-cost preparation of terpyridyl compounds, and the synthesis method has important practical application value and market prospects.

A method of controlling pests includes exposing the pests to a pest controlling amount of a triketone compound in combination with at least one second pesticide. Formulations and kits can include the combination.

The present invention relates to a liquid herbicidal composition. In particular, the present invention relates to a liquid herbicidal composition comprising triazolone herbicide and at least one co-herbicide selected from triketone herbicide and chloroacetamide herbicide; a process for preparing said composition; and a method for controlling weeds using the same.

The present disclosure relates to recombinant DNA molecules and engineered proteins useful for conferring tolerance to β-triketone herbicides such as mesotrione. The present disclosure also provides herbicide tolerant transgenic plants, plant parts, cells and seeds comprising the recombinant DNA molecules, and methods of using the same.

The invention discloses low-hardness flame-retardant silicone rubber which comprises the following components in parts by weight: 100 parts of methyl vinyl silicone rubber, 2-5 parts of a processing aid, 1-3 parts of a vulcanizing agent, 10-60 parts of a flame retardant, 8-12 parts of hyperbranched polysiloxane containing a phosphaphenanthrene structure and vinyl, 3-5 parts of epoxidized soybean oil, 1-3 parts of stearic acid and 8-12 parts of modified composite filler, the modified composite filler is a 1, 3, 5-tri [3-(trimethoxysilyl) propyl]-1, 3, 5-triazine-2, 4, 6 (1H, 3H, 5H)-triketone modified sepiolite and cellulose nanocrystal composite filler, and the flame retardant is a melamine cyanurate and hexaphenoxy cyclotriphosphazene amine compounded system. The hardness of the product is 20-24 Shore A, the UL94 flame retardant grade reaches V-0 grade, the tensile strength is 3.2-4.3 MPa, and the product has low hardness and excellent flame retardance and mechanical properties.

The application discloses an anti-aging and antibacterial film and a preparation method thereof, and relates to the technical field of film materials, and comprises the following raw materials: ethylene-vinyl alcohol copolymer, composite reinforcing agent, coupling agent, processing aid, anti-aging aid, 1-allyl-3-vinylimidazole chloride, 2-[3-(2H-benzotriazole-2-yl)-4-hydroxyphenyl]ethyl 2-methyl acrylate, amino-functionalized metal organic framework material, 1,3-bis(oxiranylmethyl)-5-(2-propenyl)-1,3,5-triazine-2,4,6(1H,3H,5H)-trione, 2,2'-bis(trifluoromethyl)diaminobiphenyl, carboxymethyl-beta-cyclodextrin, initiator and glutaraldehyde. The film has good anti-aging performance, remarkable antibacterial effect, sufficient performance stability, excellent mechanical and dynamic performance and long service life.

The present invention relates to an improved process for the preparation of Ensifentrine of Formula-I. which comprises: reacting of 1-(3,4-dimethoxyphenethyl)urea compound of Formula II with dimethylmalonate of Formula III to obtain 1-(3,4-dimethoxyphenethyl)pyrimidine-2,4,6(1H,3H,5H)-trione of Formula IV; chlorination of compound of Formula-IV to obtain 2-chloro-9,10-dimethoxy-6,7- dihydro-4H-pyrimido[6,1-a]isoquinolin-4-one of Formula V; reacting of compound of Formula V with 2,4,6-trimethyl aniline of Formula VI to obtain (E)-2-(mesitylimino)-9,10- dimethoxy-2,3,6,7-tetrahydro-4H-pyrimido[6,1-a]isoquinolin-4-one compound of Formula VII; condensation of compound of Formula VII with compound of Formula VIII or a compound of Formula IX or a salt thereof to obtain (E)-1-(2-(2-(mesitylimino)-9,10- dimethoxy-4-oxo-6,7-dihydro-2H-pyrimido[6,1-a] isoquinolin-3(4H)-yl)ethyl)urea (Ensifentrine) of Formula I; optionally converting the compound of Formula I to its pharmaceutically acceptable salts thereof. The invention further comprises purification of crude Ensifentrine by reacting with salt forming agent in a suitable solvent followed by treating with a suitable base and a suitable solvent to obtain pure Ensifentrine freebase of Formula I.

A transgenic soybean event, Gm_CSM63714, is provided. Transgenic plant cells, plant parts, plants, seeds, progeny plants, and agricultural and commodity products containing event Gm_CSM63714 are also provided. Recombinant DNA molecules unique to the event Gm_CSM63714, and methods of using and detecting Gm_CSM63714 are also provided. Soybean plants containing the event Gm_CSM63714 exhibit tolerance to benzoic acid auxins such as dicamba; phenoxy auxins such as 2,4-D; inhibitors of glutamine synthetase such as glufosinate; and P-triketone inhibitors of 4-hydroxyphenylpyruvate dioxygenase (HPPD) such as mesotrione.

The invention discloses benzobicylon herbicide ionic liquid as well as a preparation method and application thereof, and belongs to the technical field of agricultural herbicide preparations. The benzobicylon herbicide ionic liquid has a molecular structure as shown in formula (I), in the formula (I), R1, R2 and R3 are respectively and independently selected from-CH3 and-H, and R4 is selected from-C8H17,-C10H21 and-C12H25. The benzobicylon herbicide ionic liquid disclosed by the invention is obtained by reacting tertiary amine or quaternary ammonium salt with a triketone structure in an active form of benzobicylon. The benzobicylon herbicide ionic liquid has good water solubility and does not need an auxiliary agent; the plant leaf surface wetting ability is strong, the bioavailability is high, and the weed killing ability is strong; the herbicide has the characteristics of low aquatic toxicity, good crop safety and the like, and can realize application reduction and synergism of benzobicylon. Formula (I).

The invention discloses a method for synthesizing methoxyamine hydrochloride, which comprises the following steps of: adding sodium nitrite into acetylacetone under an acidic condition to synthesize 2, 3, 4-pentanetrione oxime; adjusting the reaction liquid to be alkaline, and adding a phase transfer catalyst and a methylation reagent to synthesize 3-(O-methyl oxime)-2, 3, 4-pentanetrione; and adjusting the reaction liquid to be strongly acidic, hydrolyzing, and rectifying to recover pentane-2, 3, 4-triketone, thereby obtaining the methoxyamine hydrochloride. According to the method, acetylacetone is adopted as a synthesis raw material, only an organic solvent is used for extracting an intermediate product before rectification, inorganic salt in reaction liquid is separated, the problem of recovery of difficult-to-recover substances such as ethyl alcohol and acetic acid is solved, the synthesis route is simple, operation is easy and convenient, aftertreatment is convenient, few hazardous waste is generated, investment cost is low, and labor cost and energy consumption are reduced; meanwhile, side reactions in the hydrolysis process can be reduced, and the yield of the product is improved.

This invention provides a method for preparing androstane-3,6,17-trione (E,Z)-3-[O-(2-aminoethyl)]oxime hydrochloride, comprising the following steps: benzophenone oxime reacts with 2-chloroethylamine hydrochloride in dimethyl sulfoxide, followed by acid-base adjustment, toluene extraction, hydrolysis with concentrated hydrochloric acid to remove the protecting group, and crystallization to obtain high-purity 2-aminoethylamine hydrochloride; androstane-3,6,17-triol is used as a raw material and oxidized under the catalysis of sodium bromate and ruthenium oxide (IV), quenched, separated, washed with water, and crystallized by solvent replacement with isopropanol to obtain androstane-3,6,17-trione; the 2-aminoethylamine hydrochloride solution is mixed and reacted with the trione in tetrahydrofuran solution at low temperature, followed by salting out, filtration, separation, washing with saturated brine and drying with magnesium sulfate, and purification by solvent replacement, water dissolution and concentration, and cooling crystallization to obtain the high-purity target product. This invention significantly improves the yield of the target product by optimizing reaction conditions, while achieving readily available raw materials, low cost, and industrialized production through traditional chemical reaction pathways.

The present invention relates to a composition comprising two compounds based on triazine-trione (TATO) comprising at least one thiol group and at least one unsaturated carbon-carbon bound and where the composition further comprises an amine group or compound and a Type I photoinitiator. The composition may be used for treating teeth and bone.

The invention provides a lithium ion extraction system and a preparation method and application thereof. The extraction system comprises an extraction agent, a synergistic extraction agent and a diluent, the extraction agent comprises a triketone organic compound shown as a formula I, R1 and R2 are independently selected from any one of-CH3,-CH2CH3,-CH2CH2CH3 or-CH2CH2CH2CH3, R3 is-(CH2) n-CH3, and n is 6-12. According to the method, the triketone organic compound is cooperatively matched with the synergistic extractant and the diluent, so that the extraction system has high selectivity on lithium, meanwhile, the selectivity on calcium and magnesium is reduced, the purpose of efficiently and selectively extracting lithium from a complex system is achieved, and the stability of the whole extraction process is remarkably improved. In addition, according to the lithium ion extraction system, the procedure of removing impurities such as calcium and magnesium in the early stage is omitted, and the economical efficiency of the extraction process is remarkably improved.

The invention relates to an imine reductase mutant and an application of the imine reductase mutant in synthesis of 2-methyl-10-ethyl denitroflavin. The amino acid sequence of the imine reductase mutant is as shown in SEQ ID NO. 2, and the nucleotide sequence of the imine reductase mutant is as shown in SEQ ID NO. 1. The invention also provides a method for synthesizing 2-methyl-10-ethyl denitriflavin by using the imine reductase mutant. The method comprises the following steps: (1) preparing supernate containing the imine reductase mutant by a heterologous expression method; (2) respectively preparing a solution A and a solution B by taking (5Z)-5-[(2-ethylaminophenyl) methylene]-1-methylpyrimidine-2, 4, 6 (1H, 3H, 5H)-triketone, D-glucose, glutamate dehydrogenase and reduced nicotinamide adenine dinucleoside phosphate as raw materials; and (3) carrying out reaction on the solution A and the solution B to prepare the 2-methyl-10-ethyl denitroflavin. The imine reductase mutant and the synthesis method provided by the invention overcome the defects of complex route, high cost, difficult purification, serious environmental pollution and the like of a chemical preparation method, and provide a green way for synthesis of 2-methyl-10-ethyl denitriflavin.

This invention discloses a dibenzylamine-bridged DASA molecular switch for salicylaldehyde hydrazone and its preparation method. The DASA molecule has the structure 4-((benzyl((1E,3Z)-5-(1,3-dimethyl-2,4,6-trioxotetrahydropyrimidine-5(2H)-ylidene)-4-hydroxypentan-1,3-dien-1-yl)amino)methyl)-N′-((E)-2-hydroxybenzylene)benzoylhydrazide, which is prepared by reacting the donor (E)-4-((benzylamino)methyl)-N′-(2-hydroxybenzylene)benzoylhydrazide with the acceptor 5-(furan-2-methylene)-1,3-dimethylpyrimidine-2,4,6(1H,3H,5H)-trione in methanol. Its advantages include: exhibiting excellent negative photochromic behavior in moderately strong aprotic polar solvents such as dichloromethane and acetonitrile; undergoing reversible linear-ring isomerization under visible light irradiation; showing significant changes in absorption peaks; and exhibiting good cyclic fatigue resistance. Furthermore, the introduced salicylaldehyde hydrazone group enhances its responsiveness to acids, bases, and metal ions, enabling reversible switching in various protic and aprotic solvents and selective recognition of different metal ions, thus showing broad application prospects in colorimetric sensing and metal ion detection.

Provided are compounds, compositions, and methods useful for inhibiting protein-tyrosine phosphatases, e.g., non-receptor protein-tyrosine phosphatase type 2 (PTPN2) and / or non-receptor protein-tyrosine phosphatase type 1 (PTPN1), and for treating associated diseases, disorders, and conditions that respond favorably to treatment with PTPN1 or PTPN2 inhibitors, e.g., cancers or metabolic diseases.SOLUTION: A [1-fluoro-3-hydroxynaphthalen-2-yl] - 1 λ 6,2,5 - thiadiazolidine - 1,1,3 - trione derivative represented by the following formula: (R1 to R3 are each independently H, halogen, substitutable C1 to 6 alkyl, substitutable C1 to 6 alkoxy, or the like; R4 and R5 are each independently H, halogen, substitutable C1 to 6 alkyl, or the like; R6 and R7 are each independently H. ) SELECTED DRAWING: None

The invention relates to the technical field of organic synthesis, in particular to a synthesis method of high-purity clethodim, which comprises the following steps: mixing modified crotonaldehyde and modified methyl acetoacetate for condensation reaction to prepare intermediate feed liquid; introducing nitrogen into the intermediate feed liquid for protection and dehydration to prepare a dehydrated intermediate; carrying out acylation and transposition reaction on the dehydrated intermediate to prepare propionyl triketone feed liquid; mixing a propionyl triketone feed liquid with the modified chlorinated allyloxyamine, adding a stabilizer, carrying out oximation reaction in a fourth microchannel reactor, and after the reaction is finished, carrying out cooling recrystallization, filtering and drying post-treatment to obtain the high-purity clethodim. By adopting a microchannel reactor continuous flow process and combining targeted modification treatment on three raw materials, namely crotonaldehyde, methyl acetoacetate and chloro-allyloxyamine, the conversion efficiency of each step of reaction is improved, the reaction conditions are mild, the process is controllable, the product purity is relatively high, the yield is stable, and meanwhile, side reactions are reduced.

The invention discloses a high-density fiber wallboard and a preparation method thereof, and belongs to the technical field of wallboards, the high-density fiber wallboard comprises the following components by weight: 100-200 parts of wood fiber, 50-100 parts of an inorganic filler, 30-100 parts of a triazine derivative and melamine modified urea-formaldehyde glue, 2-5 parts of a waterproof agent, and 0.4-1 part of a curing agent; the high-density fiber wallboard is prepared by adding the inorganic filler, the triazine derivative and the melamine modified urea-formaldehyde glue into the wood fiber, and the prepared high-density fiber wallboard has the effects of high strength, high modulus, high density and low formaldehyde release, and has the advantages of high strength, high modulus, high density and low formaldehyde release. The inner organizational structure is fine and dense, particularly has dense edges, can be processed into various special-shaped edges, can be directly coated without edge sealing, can achieve a better modeling effect, and has a wide application prospect.