The invention discloses an insecticidal composition containing thiacloprid amide and a biogenic insecticide. The biogenic insecticide is selected from avermectin, emamectin benzoate, spinosad or spinetoram, and the ratio by weight of the thiacloprid amide to the biogenic insecticide is 1:40-40:1. The composition can be prepared into a dosage form which is agriculturally acceptable, such as water dispersible granules, wettable powder, a suspending agent, a dispersible oil suspending agent, a microcapsule suspending agent, missible oil or a micro emulsifier. The insecticidal composition has reasonable ingredients, great insecticide effect and low chemical cost. The activity and the insecticidal effect of the insecticidal composition are not just the simple sum of the activity and the insecticidal effect of all ingredients. Compared with the traditional single preparation, the insecticidal composition not only has remarkable insecticidal effect, but also has remarkable synergistic function, mitigates resistance generation, has small preparation residual quantity and high safety, does not pollute crops and meets the safety requirements of agricultural pesticide preparations. The insecticidal composition disclosed by the invention has better control effects on rice stem borers, vegetable plutella xylostella, beet armyworms, cotton bollworms and apple olethreutid.