4904 results about "Toxicology" patented technology

The invention belongs to the technical field of pesticides, and particularly relates to a mesoionic pyrimidinium compound, and an N-oxide or salt and application thereof. The compound is shown as a general formula I: # imgabs0 #, wherein X represents a cyano group, a cyano alkyl group, an aryl group or a heterocyclic group; q1 and Q2 independently represent O or S respectively; m1, M2, M3, M4 and M5 respectively and independently represent CR9 or N, and at least two of the M1, M2, M3, M4 and M5 are N; r1, R2, R3, R4, R5, R6, R7, R8 and R9 independently represent hydrogen, nitro, amino, cyano, halogen and the like respectively. The compound has excellent prevention and control effects on pests such as chilo suppressalis, spodoptera frugiperda, armyworm, prodenia litura, peanut aphid and rice planthopper, and is safe to bees.

Formulations of pesticides are disclosed, specifically pesticidal blends of essential oils and other ingredients, that have been found to enhance the activity of the active pesticidal ingredients. The formulations may be, for example, emulsions or dust formulations. For example, a composition for controlling a target pest is disclosed that comprises at least one active agent and a formulation agent, wherein: the active agent is capable of interacting with a receptor in the target pest; the active agent has a first activity against the target pest when applied without the formulation agent and the composition has a second activity against the target pest; and the second activity is greater than the first activity.

The invention discloses a compound composition with a multi-target heart protection function as well as a preparation method and application of the compound composition. The composition is composed of a basic functional oil phase, a core antioxidant / anti-inflammatory phase, a myocardial nutrition and regulation phase and a bioavailability promotion phase in a synergistic manner, and is integrated into a composite cardiac oligopeptide and microencapsulated particle key component substance through a specific enzymolysis and microencapsulation embedding process system. The invention aims to solve the technical problems of single target spot, insufficient synergistic effect of all components, low bioavailability of active components and poor stability of the existing heart protection product, and provides a stable and easily-absorbed composite composition which can realize synergistic effect from multiple channels at the same time. Technical effect verification shows that under the condition of equal-dose sample feeding, the composition can remarkably improve the bioavailability of functional components and shows excellent myocardial cell oxidative damage resistance and myocardial ischemia improvement activity in cell and animal models, the effect is remarkably superior to that of independent use or simple physical mixing of all the components, and the composition is suitable for clinical application. And the substantial progress of synergistic interaction is proved. The composition can be used for developing various medicines, health foods and functional foods beneficial to heart health.

The application belongs to the technical field of pesticides, and particularly relates to a pyridylalanine derivative, a composition thereof and a use thereof. The compound is shown in the general formula I: wherein X1 represents hydrogen or fluorine, X2 represents hydrogen or fluorine, X3 represents hydrogen or fluorine, X4 represents hydrogen or fluorine, and X1, X2, X3 and X4 are not hydrogen at the same time; R1 and R2 independently represent hydrogen, alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkylalkyl or -(CO)R3; Y1 represents hydroxyl, alkoxyalkyloxy, trialkylsilyloxy or -O(CO)R3; Y2 represents hydrogen or alkyl; or Y1 and Y2 together form =O. The compound has excellent control effects on pests such as Myzus persicae, Lygus lineolaris, Rhopalosiphum maidis and Bemisia tabaci.

To provide a novel pest control agent composition, particularly a bactericidal composition.SOLUTION: A bactericidal or bacteriostatic composition comprising an active ingredient A selected from pyrazole compounds or salts thereof represented by formula (I): [G represents G-1; G1 represents C1-C6 haloalkyl or the like; T represents an oxygen atom or the like; RX represents C1-C6 alkyl or the like; RY represents a hydrogen atom or the like; R1 represents a hydrogen atom or the like; R2 represents a hydrogen atom or the like; R3 represents a hydrogen atom or the like; Ra represents a hydrogen atom or the like; Z represents Z-1 or the like; Z1 represents C1-C6 alkyl or the like; m5 and n5 each represent an integer of 0, 1, 2, 3, 4, or 5; and p represents an integer of 0 or 1] and an active ingredient B selected from known bactericidal or bacteriostatic compounds.SELECTED DRAWING: None

The invention belongs to the technical field of agricultural pest prevention and control, and particularly relates to an apis cerana sialoprotein RP402 and application thereof. The invention provides the sequence of the salivary protein RP402 of the point bug and the coding gene of the salivary protein RP402, and the RP402 gene is silent in a specific targeting manner through an RNA (Ribonucleic Acid) interference technology, so that the inhibition of a soybean aging process can be obviously relieved, the normal aging of leaves is accelerated, and the occurrence of a green symptom phenomenon is reduced, thereby effectively improving the normal ripening rate and the yield of soybeans. Therefore, the prevention and control method for the Eriomycorus lividus or the prevention and control method for the soybean disease green provided by the invention has the characteristics of accuracy, high efficiency and environmental protection, not only makes up for the defects of the existing prevention and control measures, but also reduces the use of chemical pesticides, reduces the environmental pollution and the risk of pest resistance to drugs, and improves the economic benefits of the Eriomycorus lividus and the soybean disease green. Popularization and application of the method can provide powerful guarantee for green and sustainable development of the soybean industry in China.

The invention discloses a preparation method of a high-adsorbability aluminum hydroxide adjuvant for livestock, which comprises the following steps: when an aluminum chloride solution reacts with alkali liquor, generating a colloidal suspension by combining pH two-step adjustment with dispersant addition; and after instant high-speed shearing and room-temperature aging, performing ultrafiltration purification to remove salts, and finally performing moist heat sterilization to obtain the suspension morphological adjuvant. The adjuvant is high in antigen adsorption rate, low in 72-hour desorption rate, large in specific surface area, uniform in particle and suitable for vaccines of pigs, cattle and poultry, and the problems that a traditional adjuvant is low in adsorption rate and poor in stability are solved.

The invention belongs to the technical field of pesticides, and particularly relates to a mesoionic pyrimidinium compound, and an N-oxide or salt and application thereof. The compound is shown as a general formula I, wherein X1 and X2 respectively and independently represent hydrogen, halogen, cyano, hydroxyl, amino, alkyl or halogenated alkyl; y1, Y2, and Y3 each independently represent hydrogen, halogen, or the like; q1 and Q2 respectively and independently represent CH2, O or S, and at least one of Q1 and Q2 is O; r1 and R2 respectively and independently represent halogen. The compound has an excellent prevention and treatment effect on pests such as spodoptera frugiperda and armyworm.

The invention relates to the technical field of cosmetics, and particularly discloses a sunscreen synergistic composition and application thereof, and the sunscreen synergistic composition comprises the following components: sugarcane extract, cyperus esculentus root oil, and Brazil palm wax (and) rice chaff wax. The sunscreen synergistic effect of the sunscreen synergistic composition is utilized, a chemical sunscreen agent with potential safety hazards can be partially replaced, the potential safety hazard coefficient is reduced due to the fact that all the sunscreen components are safe or the needed adding amount is low, and a sunscreen product which is high in sunscreen coefficient, mild in formula, low in potential safety hazards and even environmentally friendly is obtained.

Mobile or stationary air filter (L) or room fan (RL) according to Figure 1, comprising an outer wall (5), a (2) for generating an airflow (3) which is guided through an air filter material (1.1), an air inlet (2.1) and an air outlet (2.2), wherein the air filter material (1.1) contains poly(styrenesulfonic acid) (sulfonic acid biocide) (1.3) cross-linked with divinylbenzene and / or an acidic salt (1.3.1) (sulfonic acid biocide salt) of the sulfonic acid biocide (1.3) with biocidal cations, wherein the sulfonic acid biocide (1.3) and / or sulfonic acid biocide salt (1.3.1)(i) are positively and / or materially bonded to and / or in inert carriers and, in the fixed state, are in direct contact with carrier materials (1.1.7) on and / or in which biocidal Metal microparticles of a mean particle size d50 of 0.1 µm to <1,000 µm are fixed, and / or (ii) with carrier materials (1.1.7) on and / or in which biocidal metal microparticles of a mean particle size d50 of 0.1 µm to <1.000 µm are fixed, are mixed; its use and methods for the production and environmentally friendly disposal of air filter materials (1.1).

The invention belongs to the technical field of pesticides, and particularly relates to a mesoionic pyrimidinium compound, and an N-oxide or salt and application thereof. The compound is shown as a general formula I, wherein Q1 and Q2 respectively and independently represent O or S; x represents a cyano group, a cyano alkyl group, an aryl group or a heterocyclic group; y1 is halogen; y2 and Y3 each independently represent hydrogen, halogen, alkyl, or the like; and Z1, Z2, R1, R2, R3, R4, R5, R6, R7 and R8 independently represent hydrogen, halogen, cyano, nitro, alkyl and the like. The compound has an excellent prevention and treatment effect on pests such as spodoptera frugiperda, armyworm and prodenia litura.

The invention discloses a special controlled-release nitrogen fertilizer for rice containing a nitrogen signal substance and application of the special controlled-release nitrogen fertilizer. The special controlled-release nitrogen fertilizer containing the nitrogen signal substance for the rice sequentially comprises nitrogen fertilizer particles, a signal substance layer and a coating layer from inside to outside, the nitrogen fertilizer particles are quick-acting nitrogen fertilizer; the signal substance layer is a phenolic acid-beta-cyclodextrin inclusion compound; the preparation method comprises the following steps: completely dissolving beta-cyclodextrin in distilled water, heating, slowly dropwise adding an ethanol solution containing phenolic acid, a chelating agent and an antioxidant while stirring, and reacting to obtain the phenolic acid-beta-cyclodextrin inclusion compound. And the coating layer is prepared from bio-based polyol and isocyanate. According to the invention, phenolic acid is used as a signal substance, beta-cyclodextrin is added to include phenolic acid, and an antioxidant and a chelating agent are added to coat the surface of urea to prepare nitrogen fertilizer particles; and coating a coating material to obtain the special controlled-release nitrogen fertilizer containing the nitrogen signal substance for the rice. The controlled-release fertilizer not only can accurately release the nitrogen fertilizer and reduce the waste of the nitrogen fertilizer, but also can improve the yield and quality of the rice and reduce common diseases of the rice.

The invention relates to the technical field of pest control, and discloses a natural enemy insect release device for forest pest control, which comprises an unmanned aerial vehicle body capable of identifying and detecting the state of a tree, a putting mechanism arranged below the unmanned aerial vehicle body and a feeding pipe arranged in the putting mechanism, and a pull rope is arranged at the upper end of the feeding pipe. A fixing shaft is fixedly installed at the upper end of the pull rope, a plurality of guide vanes are fixedly installed on the outer side of the fixing shaft, a fixing cylinder with an opening formed in one end is fixedly installed on the guide vanes, the opening is located in the end, away from the fixing shaft, of the fixing cylinder, a balance weight bead is movably installed in the fixing cylinder, and a winding wire is connected between the balance weight bead and the cylinder wall of the fixing cylinder; the lower end of the feeding pipe is provided with a blocking piece which enables the feeding pipe to be communicated inside and outside when the feeding pipe is put. The natural enemy insect releaser aims at solving the problems that a feeding pipe of an existing natural enemy insect releaser is put on the ground, so that insects cannot quickly reach target trees, and diseases and pests of the target trees cannot be prevented and controlled.

The invention provides an insecticidal pesticide synergistic additive containing plant essential oil and a preparation method thereof, and belongs to the technical field of pesticide synergists. The insecticidal pesticide synergistic aid containing the plant essential oil comprises a synergist matrix, a penetrating agent, an emulsifying agent, a thickening agent, an anti-freezing agent and the plant essential oil. The main component of the synergistic additive is esterified vegetable oil or fatty acid alkyl ester, and the synergistic additive has the advantages of low toxicity, difficult generation of drug resistance of target organisms, environmental friendliness and the like, and can be mixed with a penetrant, an emulsifier and a thickener for use, so that the wetting and infiltration capacity of pesticide liquid can be remarkably enhanced, a wax layer structure can be destroyed, the permeability of the pesticide liquid can be improved, and the pesticide effect can be improved. The added plant essential oil belongs to a natural active substance, has the characteristics of being green and environment-friendly, and can be matched with different pesticide formulations such as insecticides, bactericides, herbicides and the like for use.

The invention discloses application of ursolic acid in resisting fish ichthyophthiriasis. The ursolic acid has a remarkable killing effect on ichthyophthirius multifilis in an in-vitro stage, and the 4-hour half effective insecticidal concentration (4h-EC50) of the ursolic acid on a grazing body is 0.3774 mg / L; and the 22-hour half effective insecticidal concentration (22h-EC 50) on the capsule is 4.931 mg / L. An acute toxicity test shows that the 96-hour median lethal concentration (96h-LC50) of ursolic acid to goldfish is 9.358 mg / L, the therapeutic index (TI = 96h-LC50 / 4h-EC50) is up to 24.8, and the safety of ursolic acid is remarkably superior to that of a traditional medicine. Ursolic acid used in the invention is a plant-derived active component, has the characteristics of high environmental compatibility and low biological accumulation, meets the development requirements of green fishery, and has an industrialization basis for being developed into eco-friendly aquatic products.

The invention relates to the technical field of green prevention and treatment of dendroctonus valerieus, in particular to a dendroctonus valerieus repellent as well as a preparation method and application thereof. The repelling component comprises fenchone. The fenchone is found to have an obvious repelling effect on the dendroctonus resurus, and meanwhile, the fenchone can be used as a repellent for the dendroctonus resurus, and the dendroctonus resurus can be repelled in production to protect an ecological system of a pine forest. The repellent has the advantages of good repelling effect, stability, environmental friendliness and wide industrialization prospect.

The invention relates to the technical field of pesticides, in particular to a validamycin / thifluzamide double-loaded preparation with an acid-base response characteristic. The preparation method comprises the following steps: firstly, loading thifluzamide by using calcium carbonate to form a microsphere structure, and simultaneously loading validamycin and thifluzamide calcium carbonate microspheres by using sodium carboxymethyl cellulose and sodium alginate as carrier materials to construct the double-load pesticide preparation. The validamycin / thifluzamide double-loaded preparation provided by the invention has the characteristic of responding to the pH value of the environment, and can simultaneously realize quick release of validamycin and long-acting release of thifluzamide, so that the pesticide effect is remarkably improved. Besides, the validamycin / thifluzamide double-loaded preparation provided by the invention has good leaf surface wettability and release performance, has a relatively good prevention effect on rice sheath blight disease, and has relatively high safety to aquatic organisms represented by zebra fish.

The invention belongs to the technical field of novel pesticides, and particularly provides a bactericide suspending agent and a preparation method thereof.The effective component of the bactericide suspending agent is prothioconazole, and on the basis of the effective component of the bactericide suspending agent, microencapsulated oxidized vegetable oil accounting for 5-15% of the weight of the whole bactericide is added to serve as a synergistic auxiliary agent. The prothioconazole bactericide has the advantages that the adhesion capacity of the prothioconazole bactericide on the surfaces of crops can be obviously improved, the adverse effects caused by environmental factors such as rain wash are reduced, and the absorption of the bactericide is facilitated, so that the synergistic effect is achieved.

The invention relates to a pesticide residue detection test strip as well as a preparation method and application thereof, in particular to a rapid detection technology based on an enzyme inhibition method and a chitosan non-woven fabric carrier. The test strip can specifically detect organophosphorus and carbamate pesticides such as trichlorfon, malathion and phoxim through the enzyme activity inhibition principle, the detection limit of the pesticides such as phoxim is as low as 0.1 mg / kg, the developing intensity is in negative correlation with the pesticide concentration, and semi-quantitative judgment can be achieved. The preparation process is simple, the chitosan non-woven fabric is adopted as a fixed carrier, the material is environment-friendly and degradable, the enzyme activity recovery rate reaches 90%, the stability is excellent (the enzyme activity recovery rate can be preserved for 60 days at the temperature of 4 DEG C in a dark place), sample pretreatment is not needed in detection operation, a result can be obtained at the normal temperature for 15 min, the stability and repeatability are good, and the problems that a traditional instrument is high in detection cost and long in time consumption are solved; the method has a remarkable basic popularization value.

The invention discloses a preparation method and application of a sophocarpidine nano-pesticide, dendritic mesoporous silica nanoparticles are ultrasonically dispersed in a methanol solution of sophocarpidine, the mixture is stirred for 45-50 h in a dark place at 10-30 DEG C for a reaction, after the reaction, precipitates are centrifugally collected, washed and freeze-dried, and the sophocarpidine nano-biopesticide is obtained. The sophocarpidine nano biopesticide is prepared by taking dendritic mesoporous silica nanoparticles as a carrier, and dendritic mesoporous silica is of a dendritic mesoporous structure and has the characteristics of larger porosity, uniform particle size, high drug loading rate, slow control effect and the like. The dendritic mesoporous silica has the advantages that the dendritic mesoporous silica can be used for preventing and treating trunk-boring, basal and root-eating pests, the matrine as a biological pesticide can avoid the problems of photolysis and the like after being loaded into the dendritic mesoporous silica, the prevention and treatment effect is improved, the drug resistance of the pests is reduced, the goals of reduction and synergism are achieved, and a new thought is provided for sustainable prevention and treatment.

The invention provides a method for detecting free amino acids in camellia oleosa seed oil, and establishes a method for detecting the free amino acids in the camellia oleosa seed oil based on ultra-high performance liquid chromatography-tandem mass spectrometry (UPLC-MS / MS), which comprises the following steps: pre-treating various amino acids in the camellia oleosa seed oil by using a non-derivation method; the problems of complicated operation, impurity interference and the like caused by derivatization are avoided, the extraction solvent is environment-friendly and economical, the extraction efficiency is high, and the pretreatment time is greatly shortened; then selecting a proper chromatographic column and a mobile phase, separating a plurality of free amino acids under the condition of not introducing excessive derivatization agents and ion pair reagents, and controlling the collection time to be 12 minutes. The method for detecting the free amino acids in the camellia oleosa seed oil has the characteristics of no need of derivatization treatment, simplicity and convenience in operation, high detection efficiency and good sensitivity and accuracy, and can effectively separate and detect 14 free amino acids such as alanine, phenylalanine and aspartic acid in the camellia oleosa seed oil.

The present invention relates to the technical field of pesticides, and in particular to a pyrazole amide compound and a use thereof. The compound is as shown in general formula I, wherein Q represents O or S, W represents CH or N, X represents hydrogen, halogen, alkyl, etc., Y represents halogen or alkyl, Z represents alkyl, alkenyl, alkynyl, cycloalkyl, etc., and M represents hydrogen or alkyl. The compound has good prevention and treatment activity on pests such as green peach aphids, peanut aphids, and bird cherry-oat aphids.

The invention provides an anti-stain inducer as well as a preparation method and a use method thereof. According to the anti-waterlogging inducer, 0.01-0.02 g of potassium persulfate is mixed with a corresponding dosage of a synergistic compound agent in 1 L of an earthworm enzyme solution, a proper amount of ROS is induced in plants by spraying of potassium persulfate, ROS is used as a stress resistance signal, a crop plant defense reaction is activated, a stress memory is formed, and the anti-waterlogging inducer has a good anti-waterlogging effect. Therefore, the stress response of the plant can be quickly activated in a subsequent stress environment, and the stress resistance of the plant is improved. The anti-stain inducer provided by the invention is low in cost and easy for large-scale production. When the wheat waterlogging stress occurs, the wheat waterlogging resistance can be effectively improved by spraying the wheat waterlogging stress resisting agent before the wheat is subjected to waterlogging stress in a simple and convenient use mode easy for farmers to operate, so that the yield and the quality of the wheat are remarkably improved. The inducer provided by the invention avoids the problem that the existing remedial conditioning agent is difficult to apply in time under the condition of heavy rainfall, and provides a new solution for agricultural disaster resistance and reduction.

The invention belongs to the technical field of pesticides, and particularly relates to a mesoionic pyrimidinium compound, and an N-oxide or salt and application thereof. The compound is shown as a general formula I, wherein Q1 and Q2 respectively and independently represent O or S; x represents a cyano group, a cyano alkyl group, an aryl group or a heterocyclic group; y1, Y2, Y3, Z1, Z2, R1, R2, R3, R4, R5, R6, R7, and R8 independently represent hydrogen, halogen, a cyano group, a nitro group, an alkyl group, etc. The compound has an excellent prevention and treatment effect on pests such as spodoptera frugiperda, armyworm and prodenia litura.

The invention discloses an ostrinia furnacalis sex attractant and a preparation method and application thereof.The sex attractant is prepared from sex pheromone and a solvent, and the sex pheromone comprises cis-12-tetradecene acetate, trans-12-tetradecene acetate and tetradecene acetate; the mass ratio of the cis-12-tetradecene acetate to the trans-12-tetradecene acetate is 3: (1-2), and the ratio of the mass sum of the cis-12-tetradecene acetate and the trans-12-tetradecene acetate to the mass of the tetradecene acetate is 3: (0.8-1.2). The sex attractant provided by the invention can significantly increase the trapping amount of Asiatic corn borers, has good stability and accuracy, and can be used for monitoring, early warning, trapping, killing and preventing Asiatic corn borers in South China.

The invention belongs to the technical field of pesticides, and particularly relates to a mesoionic pyrimidinium compound, and an N-oxide or salt and application thereof. The compound is shown as a general formula I, wherein X and Z respectively and independently represent hydrogen, alkyl, alkenyl, alkynyl, naphthenic base and the like; y represents chlorine or bromine. The compound has an excellent prevention and treatment effect on pests such as spodoptera frugiperda, armyworm and prodenia litura.

The invention discloses a composite curcumin nano pesticide and a preparation method and application thereof.The nano pesticide comprises a carrier and curcumin loaded on the carrier, the carrier is polydopamine-sodium lignin sulfonate, and the polydopamine-sodium lignin sulfonate is formed by polymerizing dopamine hydrochloride on the surface of lignin; the preparation method comprises the following steps: preparing a curcumin solution, adding the polydopamine-sodium lignin sulfonate powder, fully dispersing, slowly stirring under a dark condition until a yellow solution becomes dark red, and removing a solvent to obtain the polydopamine-sodium lignin sulfonate-curcumin. The nano pesticide provided by the invention takes polydopamine-sodium lignin sulfonate as a carrier, so that the drug has pH and photo-thermal response controlled release function, burst release of curcumin is avoided, and the stability and bioavailability of curcumin are improved.

The invention discloses a pesticide compound composition of abamectin and dsRNA (double-stranded ribonucleic acid) and application of the pesticide compound composition in prevention and control of nematodes. According to the invention, dsRNA is respectively designed and synthesized for five Mcm genes of bursaphelenchus xylophilus, and nucleotide sequences of positive-sense strands of the dsRNA are respectively shown as SEQ ID No.1-SEQ ID No.5; the synthesized dsRNA and abamectin of different components are compounded to obtain the pesticide compound composition, the pesticide compound composition shows a remarkable synergistic effect in the aspect of preventing and treating pine wood nematode diseases, and the nematode killing effect of combined use of the dsRNA and the abamectin is superior to that of single use of any agent; the pesticide compound composition has the potential to become a novel trunk injection for preventing the pine wood nematode disease.

The present invention discloses a livestock and poultry manure biochar-based fertilizer, comprising the following raw materials in parts by weight: 10-42% of dilute protein solution and collagenase-modified livestock and poultry manure biochar, 20-40% of urea, 7-25% of diammonium phosphate, 7-24% of potassium chloride or potassium sulfate, 0.5-1% of modified starch, and 6-23% of bentonite. The livestock and poultry manure is selected from one of chicken manure, cow manure, and pig manure. After the biochar is modified with collagenase, the surface of the biochar has more phenolic hydroxyl groups, carboxyl groups, aldehyde groups, and hydroxyl functional groups, which are effective for NH4 + , PO4 3‑ , K + , has a stronger adsorption effect, collagenase modification makes the protein distribution more uniform, and the generated groups form a stable chemical bond with the biochar surface: it improves the dispersibility of the modified biochar in aqueous solution and reduces agglomeration; it has better chemical stability in acidic and alkaline environments.