6179 results about "Toxicology" patented technology

The present invention relates to the technical field of pesticides, and discloses a biological agent-based rice sheath blight disease efficient control agent, which comprises an active flora, a carrier, an auxiliary agent and a disease resistance enhancing factor, the active flora is used for combining humidity, pH and temperature response type materials so as to make the bacterial agent dynamically released, and the disease resistance enhancing factor is used for controlling the disease resistance of the rice sheath blight disease. The carrier is used for enabling the active ingredients to be slowly released in a field environment and keep stability, the auxiliary additive is used for improving the activity, adhesiveness and soil adaptability of the fungicide, and the disease-resistant enhancing factor is used for expanding and improving the adaptability of the control agent. The ratio of the active flora to the carrier to the auxiliary additive to the disease-resistant enhancing factor is 10: 50: 13: 27. Through the synergistic effect of various functional strains and the combination of the dynamic release carrier, the occurrence and propagation of the rice sheath blight disease are effectively inhibited, the prevention and treatment rate can reach 75-85%, and the prevention and treatment effect is obviously higher than that of a traditional chemical pesticide or a single fungicide.

The invention relates to bacillus velezensis SMB1 and application thereof in prevention and treatment of plant diseases, and belongs to the technical field of biological prevention and treatment of plant diseases. The strain is preserved in the China Center for Type Culture Collection on November 27, 2024, the preservation address is Luojia mountain, Luojia mountain, eight road, Wuchang District, Wuhan City, Hubei Province, and the preservation number is CCTCC NO: M20242647. The bacillus velezensis SMB1 provided by the invention has a remarkable bacteriostatic effect on plant pathogenic fungi, plant pathogenic oomycetes, plant pathogenic bacteria and animal pathogenic bacteria, has an extremely good broad-spectrum bacteriostatic function, has a great application potential in biological control of plant diseases, can reduce the use of chemical pesticides, and has a good application prospect. The pesticide residue in agricultural products is reduced, the environment is protected, and the urgent demand on pollution-free agricultural product production at present is met.

To provide greening methods that reduce feeding and trampling damage caused by deer.SOLUTION: At least 50% of the expected number of plants to emerge from the total amount of seeds to be applied to the land to be revegetated consists of seeds from selected plants that meet at least one of the following criteria: (a) taste evaluation, (b) smell evaluation, (c) pain evaluation, (d) difficulty of consumption evaluation, and (e) regenerative ability evaluation, and the seeds comprise at least one selected from the following: Creeping red fescue, Creeping bentgrass, Bermuda grass, Red top, Kentucky bluegrass, Hard fescue, Chewing fescue, Japanese silvergrass, Pennisetum alopecuroides, Zoysia japonica, Eragrostis ferruginea, Lespedeza juncea, Sophora sophora, Boehmeria sieboldiana, Perilla citriodora, Perilla frutescens, Persicaria tinctoria, Boenninghausenia albiflora, Plantago asiatica, Pieris japonica, Edgeworthia chrysantha, and Indigofera pseudotinctoria. A method comprises giving nitrogen fertilizer equivalent to a nitrogen content of 8 g / m2 or more and silica fertilizer equivalent to a silica content of 10 g / m2 or more to the land to be revegetated.SELECTED DRAWING: Figure 1

The invention discloses an N-cyclobutyl substituted benzamide isoxazoline compound as well as a preparation method and application thereof. The N-cyclobutyl substituted benzamide isoxazoline compound has broad-spectrum and efficient insecticidal activity at a low dosage, and has a remarkable effect on prevention and treatment of diseases and insect pests in agriculture and forestry and pests in the field of sanitation; moreover, the pesticide composition is safer to non-target organisms, can reduce the damage to plants, non-target organisms and human beings due to overhigh pesticide concentration, and is more beneficial to crop protection and environmental safety.

The invention discloses a copper-based nano-enzyme, a preparation method thereof and application of the copper-based nano-enzyme in organophosphorus pesticide detection, and belongs to the technical field of pesticide residue detection. The copper-based nano-enzyme has a netted-like structure, a high specific surface area and many active sites, the valence state of a copper element is zero-valence Cu, Cu < + > and Cu < 2 + >, the copper-based nano-enzyme has high peroxidase-like activity and laccase-like activity, the detection limit is low, and glyphosate can be sensitively detected; and glyphosate, glufosinate-ammonium and isazofos can be well distinguished from six organophosphorus pesticides with medium concentration, and the method has high selectivity. The nano enzyme provided by the invention is prepared from ammonium citrate and copper nitrate in an N, N-dimethylformamide (DMF) solution by using a solvothermal method; the preparation process of the nano enzyme is simple.

The invention belongs to the technical field of pesticides, and particularly relates to a mesoionic pyrimidinium compound, and an N-oxide or salt and application thereof. The compound is shown as a general formula I: # imgabs0 #, wherein X represents a cyano group, a cyano alkyl group, an aryl group or a heterocyclic group; q1 and Q2 independently represent O or S respectively; m1, M2, M3, M4 and M5 respectively and independently represent CR9 or N, and at least two of the M1, M2, M3, M4 and M5 are N; r1, R2, R3, R4, R5, R6, R7, R8 and R9 independently represent hydrogen, nitro, amino, cyano, halogen and the like respectively. The compound has excellent prevention and control effects on pests such as chilo suppressalis, spodoptera frugiperda, armyworm, prodenia litura, peanut aphid and rice planthopper, and is safe to bees.

Formulations of pesticides are disclosed, specifically pesticidal blends of essential oils and other ingredients, that have been found to enhance the activity of the active pesticidal ingredients. The formulations may be, for example, emulsions or dust formulations. For example, a composition for controlling a target pest is disclosed that comprises at least one active agent and a formulation agent, wherein: the active agent is capable of interacting with a receptor in the target pest; the active agent has a first activity against the target pest when applied without the formulation agent and the composition has a second activity against the target pest; and the second activity is greater than the first activity.

The invention discloses a compound composition with a multi-target heart protection function as well as a preparation method and application of the compound composition. The composition is composed of a basic functional oil phase, a core antioxidant / anti-inflammatory phase, a myocardial nutrition and regulation phase and a bioavailability promotion phase in a synergistic manner, and is integrated into a composite cardiac oligopeptide and microencapsulated particle key component substance through a specific enzymolysis and microencapsulation embedding process system. The invention aims to solve the technical problems of single target spot, insufficient synergistic effect of all components, low bioavailability of active components and poor stability of the existing heart protection product, and provides a stable and easily-absorbed composite composition which can realize synergistic effect from multiple channels at the same time. Technical effect verification shows that under the condition of equal-dose sample feeding, the composition can remarkably improve the bioavailability of functional components and shows excellent myocardial cell oxidative damage resistance and myocardial ischemia improvement activity in cell and animal models, the effect is remarkably superior to that of independent use or simple physical mixing of all the components, and the composition is suitable for clinical application. And the substantial progress of synergistic interaction is proved. The composition can be used for developing various medicines, health foods and functional foods beneficial to heart health.

The application belongs to the technical field of pesticides, and particularly relates to a pyridylalanine derivative, a composition thereof and a use thereof. The compound is shown in the general formula I: wherein X1 represents hydrogen or fluorine, X2 represents hydrogen or fluorine, X3 represents hydrogen or fluorine, X4 represents hydrogen or fluorine, and X1, X2, X3 and X4 are not hydrogen at the same time; R1 and R2 independently represent hydrogen, alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkylalkyl or -(CO)R3; Y1 represents hydroxyl, alkoxyalkyloxy, trialkylsilyloxy or -O(CO)R3; Y2 represents hydrogen or alkyl; or Y1 and Y2 together form =O. The compound has excellent control effects on pests such as Myzus persicae, Lygus lineolaris, Rhopalosiphum maidis and Bemisia tabaci.

The invention discloses design and application of a colorimetric-catalytic signal enhancement combined graphene oxide nano-enzyme rapid pesticide residue detection platform, and belongs to the technical field of immunochromatography detection. Graphene (GO) is used as a substrate, 30 nm Pt nanoparticles are adsorbed on the surface of the substrate to provide a colorimetric signal, and gaps of Pt NPs are filled with 5 nm AuIr nanoparticles to enhance the catalytic performance of the substrate, so that the colorimetric / catalytic dual-signal enhanced nano-enzyme is prepared. The GO (at) Pt30-AuIr nano-enzyme is synergistically assembled with Pt NPs and AuIr NPs by utilizing the large specific surface area, excellent stability and dispersibility of GO, so that the catalytic performance of the system is remarkably improved. The method has the beneficial effects that a GO-Pt30-AuIr-LFA-based detection system can realize high-sensitivity dual detection on heavy metal cadmium ions (Cd < 2 + >) and pesticide residue imidacloprid (IMI) within 20 minutes, and the detection limit reaches the level of pg / mL. The detection method provided by the research shows significant application potential in the aspect of rapid screening of small molecules in a complex matrix, and a new technical approach is provided for food safety monitoring.

The invention relates to the technical field of microbial agents, in particular to a composite microbial agent and application of the composite microbial agent in prevention and treatment of forest root diseases, and the composite microbial agent comprises the following components in parts by weight: 15-25 parts of Trichoderma harzianum ATCC 20847; 10 to 20 parts of bacillus subtilis ATCC 605, 10 to 20 parts of bacillus subtilis ATCC 605, 10 to 20 parts of bacillus subtilis ATCC 606 and 10 to 20 parts of bacillus subtilis ATCC 607. 5-10 parts of a seaweed extract; 3 to 8 parts of chitosan; 2-5 parts of humic acid; 1 to 3 parts of glycine betaine; 0.5 to 1.5 parts of a trace element compound; 30 to 40 parts of perlite powder; according to the present invention, the fertilizer has characteristics of significant inhibition effect on a variety of forest root pathogenic bacteria, wide prevention and control spectrum, and long-term and stable disease prevention effect by adjusting the rhizosphere micro-ecosystem. Diseases are prevented and controlled, and the growth and root development of the forest trees are remarkably promoted.

The invention belongs to the technical field of pesticides, and particularly relates to a pyridyl alkoxy pyrimidine compound and application thereof. The compound is shown as a formula I: # imgabs0 #, wherein X and Y respectively and independently represent hydrogen, hydroxyl, alkyl, alkoxy, alkenyloxy, alkynyloxy and the like; z represents hydrogen, halogen, a cyano group, an amino group, a nitro group, a formyl group, a cyano alkyl group, a hydroxyalkyl group, an alkyl group, an alkenyl group, an alkynyl group and the like. The compound or the salt thereof has an excellent effect as an agricultural and horticultural insecticide.

The present invention relates to the technical field of surfactants, and discloses a preparation method of a modified polycarboxylate surfactant and its application in pesticide preparations. The present invention uses 3-hexene-1,6-diamine and epichlorohydrin as raw materials, and obtains 1,6-tetraglycidylamine-3-hexene through ring opening and ring closing reactions. 1,6-tetraglycidylamine-3-hexene is used twice to react with sodium bisulfite and phosphoric acid in sequence to obtain tetrasulfonate-based hexene and tetraphosphate-based hexene, and then the two are copolymerized with acrylic acid and methacrylate to obtain a modified polycarboxylate surfactant. The modified polycarboxylate surfactant prepared by the present invention has excellent dispersibility, heat storage stability and high suspension rate.

The invention relates to the technical field of pesticide production, in particular to a synthesis method of 1-methyl-3-trifluoromethyl-4-chloromethyl-5-difluoromethoxy-1-H-pyrazole, which at least comprises the following steps: firstly, mixing trioxymethylene and 1-methyl-3-trifluoromethyl-5-difluoromethoxy-1-H-pyrazole to prepare a solution A; the solution A and chlorosulfonic acid are mixed and then subjected to a chloromethylation reaction, 1-methyl-3-trifluoromethyl-4-chloromethyl-5-difluoromethoxy-1-H-pyrazole is obtained through aftertreatment after sampling detection is qualified, and the method is high in product yield, high in purity, low in production cost, high in production efficiency, easy to operate, capable of meeting the green and environment-friendly requirements and suitable for industrial production. The industrial production is easy to realize.

To provide a novel pest control agent composition, particularly a bactericidal composition.SOLUTION: A bactericidal or bacteriostatic composition comprising an active ingredient A selected from pyrazole compounds or salts thereof represented by formula (I): [G represents G-1; G1 represents C1-C6 haloalkyl or the like; T represents an oxygen atom or the like; RX represents C1-C6 alkyl or the like; RY represents a hydrogen atom or the like; R1 represents a hydrogen atom or the like; R2 represents a hydrogen atom or the like; R3 represents a hydrogen atom or the like; Ra represents a hydrogen atom or the like; Z represents Z-1 or the like; Z1 represents C1-C6 alkyl or the like; m5 and n5 each represent an integer of 0, 1, 2, 3, 4, or 5; and p represents an integer of 0 or 1] and an active ingredient B selected from known bactericidal or bacteriostatic compounds.SELECTED DRAWING: None

The invention belongs to the technical field of agricultural pest prevention and control, and particularly relates to an apis cerana sialoprotein RP402 and application thereof. The invention provides the sequence of the salivary protein RP402 of the point bug and the coding gene of the salivary protein RP402, and the RP402 gene is silent in a specific targeting manner through an RNA (Ribonucleic Acid) interference technology, so that the inhibition of a soybean aging process can be obviously relieved, the normal aging of leaves is accelerated, and the occurrence of a green symptom phenomenon is reduced, thereby effectively improving the normal ripening rate and the yield of soybeans. Therefore, the prevention and control method for the Eriomycorus lividus or the prevention and control method for the soybean disease green provided by the invention has the characteristics of accuracy, high efficiency and environmental protection, not only makes up for the defects of the existing prevention and control measures, but also reduces the use of chemical pesticides, reduces the environmental pollution and the risk of pest resistance to drugs, and improves the economic benefits of the Eriomycorus lividus and the soybean disease green. Popularization and application of the method can provide powerful guarantee for green and sustainable development of the soybean industry in China.

The invention discloses a pH response type pesticide microcapsule and a preparation method thereof, and the preparation method comprises the following steps: mixing a pesticide raw material, an organic cosolvent and a diisocyanate monomer to obtain an oil phase; mixing a surfactant with water to obtain a water phase; adding the oil phase into the water phase, and carrying out shear emulsification to obtain O / W type emulsion; and mixing the O / W type emulsion with an aqueous solution of polyamine containing the vanillyl Schiff base structure, and carrying out an interfacial polymerization reaction to obtain the pH response type polyurethane pesticide microcapsule with the vanillyl Schiff base structure. According to the invention, the organic cosolvent and diisocyanate are used as oil phase components, can dissolve the raw pesticide and do not react with the raw pesticide, has good pH responsiveness, can realize stimulation response to an acid environment caused by pathogenic bacteria infected crops, improves the utilization rate of the pesticide, and reduces the usage amount of the pesticide.

The invention discloses a preparation method of a high-adsorbability aluminum hydroxide adjuvant for livestock, which comprises the following steps: when an aluminum chloride solution reacts with alkali liquor, generating a colloidal suspension by combining pH two-step adjustment with dispersant addition; and after instant high-speed shearing and room-temperature aging, performing ultrafiltration purification to remove salts, and finally performing moist heat sterilization to obtain the suspension morphological adjuvant. The adjuvant is high in antigen adsorption rate, low in 72-hour desorption rate, large in specific surface area, uniform in particle and suitable for vaccines of pigs, cattle and poultry, and the problems that a traditional adjuvant is low in adsorption rate and poor in stability are solved.

The present disclosure relates to agrochemical combinations. More particularly, the present disclosure relates to a herbicidal combination comprising at least one carbamate herbicide and at least a second herbicide. The disclosure further relates to a herbicidal composition comprising asulam, at least a second herbicide and at least an agriculturally acceptable excipient.

The invention belongs to the technical field of pesticides, and particularly relates to a mesoionic pyrimidinium compound, and an N-oxide or salt and application thereof. The compound is shown as a general formula I, wherein X1 and X2 respectively and independently represent hydrogen, halogen, cyano, hydroxyl, amino, alkyl or halogenated alkyl; y1, Y2, and Y3 each independently represent hydrogen, halogen, or the like; q1 and Q2 respectively and independently represent CH2, O or S, and at least one of Q1 and Q2 is O; r1 and R2 respectively and independently represent halogen. The compound has an excellent prevention and treatment effect on pests such as spodoptera frugiperda and armyworm.

The invention relates to the technical field of cosmetics, and particularly discloses a sunscreen synergistic composition and application thereof, and the sunscreen synergistic composition comprises the following components: sugarcane extract, cyperus esculentus root oil, and Brazil palm wax (and) rice chaff wax. The sunscreen synergistic effect of the sunscreen synergistic composition is utilized, a chemical sunscreen agent with potential safety hazards can be partially replaced, the potential safety hazard coefficient is reduced due to the fact that all the sunscreen components are safe or the needed adding amount is low, and a sunscreen product which is high in sunscreen coefficient, mild in formula, low in potential safety hazards and even environmentally friendly is obtained.

The present invention relates to fungicidal mixtures comprising at least one substituted pyridine (compound I) and at least one active compound II in a weight ratio of from 100: 1 to 1: 100; to a method for controlling phytopathogenic harmful fungi using a mixture of at least one compound I and at least one compound II in a weight ratio of 100: 1 to 1: 100; to the use of a mixture comprising compound I and compound II for controlling phytopathogenic harmful fungi; to agrochemical compositions comprising these mixtures; and to agrochemical compositions further comprising seeds.

The present disclosure relates to liquid (e.g., water-soluble) compositions comprising antimethanogenic compounds, and methods of administering the same to reduce enteric methane emissions from ruminant animals, and / or improve feed-efficiency. Certain disclosed compositions exhibit improved rapid effect over prior art compositions. The disclosure further relates to methods of concentrating antimethanogenic compounds, extracting antimethanogenic compounds, and methods of increasing the bioavailability of antimethanogenic compounds.

A synergistic insecticidal composition comprising of (A) Isocycloseram; (B) an insecticide from chlorantraniliprole, cyantraniliprole, cyclaniliprole, tetraniliprole, tetrachlorantraniliprole, tyclopyrazoflor, cyhalodiamide, flubendiamide, fluchlordiniliprole, tiorantraniliprole; and (C) one or more insecticides selected from the given list thereof. The present invention further relates to process for preparing the said compositions in specific amount. The present invention further relates to the process for preparing the said composition along with at least one formulation excipient; and formulations thereof. The present invention further relates to the synergistic compositions, wherein active ingredient present in fixed amount shows synergy in an insecticidal activity.

The invention discloses application of a microbial natural product GameXPeptide-A in improving the pest control effect of an insecticide, and belongs to the technical field of biological control. Experiments prove that after the GameXPeptide-A is combined with insecticides such as metarhizium anisopliae, beauveria bassiana, nuclear polyhedrosis virus, 4% of abamectin acetamiprid, 10% of spinosad emamectin benzoate, 30% of etoxazole nitrile, 45% of biphenyl etoxazole, 5% of emamectin benzoate, 5% of chlorantraniliprole, 5% of abamectin and the like for use, the insecticidal effect is obviously improved; the insecticidal activity of the insecticide on agricultural pests such as thrips, ostrinia nubilalis and prodenia litura can be effectively improved, so that the substance can be combined with different insecticides for use, and the insecticidal activity of the insecticide on crop pests in agricultural production such as lepidoptera, diptera, coleoptera, orthoptera, hemiptera and homoptera is improved; the compound can be used for development and application of novel pest immunosuppressants or insecticide synergists.

The invention discloses a gamma-aminobutyric acid gated chloride ion channel allosteric modifier compound and an application thereof, namely (S)-4-(5-(3-chloro-5-(trifluoromethyl) phenyl)-5-(trifluoromethyl)-4, 5-dihydroisoxazole-3-yl)-2-methyl-N-(2-oxo-2-((2, 2, 2-trifluoroethyl) amino) ethyl) benzamide, and a preparation method of the gamma-aminobutyric acid gated chloride ion channel allosteric modifier compound. The compound has an excellent control effect on pests of thysanoptera, acarina, lepidoptera and the like, is very friendly to bees and high in environmental ecological safety, can be used for preparing efficient, low-toxicity and safe insecticides, and has a wide application prospect in agricultural production.

Mobile or stationary air filter (L) or room fan (RL) according to Figure 1, comprising an outer wall (5), a (2) for generating an airflow (3) which is guided through an air filter material (1.1), an air inlet (2.1) and an air outlet (2.2), wherein the air filter material (1.1) contains poly(styrenesulfonic acid) (sulfonic acid biocide) (1.3) cross-linked with divinylbenzene and / or an acidic salt (1.3.1) (sulfonic acid biocide salt) of the sulfonic acid biocide (1.3) with biocidal cations, wherein the sulfonic acid biocide (1.3) and / or sulfonic acid biocide salt (1.3.1)(i) are positively and / or materially bonded to and / or in inert carriers and, in the fixed state, are in direct contact with carrier materials (1.1.7) on and / or in which biocidal Metal microparticles of a mean particle size d50 of 0.1 µm to <1,000 µm are fixed, and / or (ii) with carrier materials (1.1.7) on and / or in which biocidal metal microparticles of a mean particle size d50 of 0.1 µm to <1.000 µm are fixed, are mixed; its use and methods for the production and environmentally friendly disposal of air filter materials (1.1).

The present invention relates to fungicidal mixtures comprising at least one substituted pyridine (compound I) and at least one active compound II in a weight ratio of from 100: 1 to 1: 100; to a method for controlling phytopathogenic harmful fungi using a mixture of at least one compound I and at least one compound II in a weight ratio of 100: 1 to 1: 100; to the use of a mixture comprising compound I and compound II for controlling phytopathogenic harmful fungi; to agrochemical compositions comprising these mixtures; and to agrochemical compositions further comprising seeds.

The invention belongs to the technical field of pesticides, and particularly relates to a mesoionic pyrimidinium compound, and an N-oxide or salt and application thereof. The compound is shown as a general formula I, wherein Q1 and Q2 respectively and independently represent O or S; x represents a cyano group, a cyano alkyl group, an aryl group or a heterocyclic group; y1 is halogen; y2 and Y3 each independently represent hydrogen, halogen, alkyl, or the like; and Z1, Z2, R1, R2, R3, R4, R5, R6, R7 and R8 independently represent hydrogen, halogen, cyano, nitro, alkyl and the like. The compound has an excellent prevention and treatment effect on pests such as spodoptera frugiperda, armyworm and prodenia litura.

The present disclosure provides batteries that have a reduced risk or no risk of esophageal or gastrointestinal damage in a conductive aqueous environment, such as when accidentally swallowed. The batteries are, in some embodiments, nominally 9V, 3V or 1.5V coin or button cell-type batteries.