2933 results about "Toxicology" patented technology

The invention discloses a compound composition with a multi-target heart protection function as well as a preparation method and application of the compound composition. The composition is composed of a basic functional oil phase, a core antioxidant / anti-inflammatory phase, a myocardial nutrition and regulation phase and a bioavailability promotion phase in a synergistic manner, and is integrated into a composite cardiac oligopeptide and microencapsulated particle key component substance through a specific enzymolysis and microencapsulation embedding process system. The invention aims to solve the technical problems of single target spot, insufficient synergistic effect of all components, low bioavailability of active components and poor stability of the existing heart protection product, and provides a stable and easily-absorbed composite composition which can realize synergistic effect from multiple channels at the same time. Technical effect verification shows that under the condition of equal-dose sample feeding, the composition can remarkably improve the bioavailability of functional components and shows excellent myocardial cell oxidative damage resistance and myocardial ischemia improvement activity in cell and animal models, the effect is remarkably superior to that of independent use or simple physical mixing of all the components, and the composition is suitable for clinical application. And the substantial progress of synergistic interaction is proved. The composition can be used for developing various medicines, health foods and functional foods beneficial to heart health.

The application belongs to the technical field of pesticides, and particularly relates to a pyridylalanine derivative, a composition thereof and a use thereof. The compound is shown in the general formula I: wherein X1 represents hydrogen or fluorine, X2 represents hydrogen or fluorine, X3 represents hydrogen or fluorine, X4 represents hydrogen or fluorine, and X1, X2, X3 and X4 are not hydrogen at the same time; R1 and R2 independently represent hydrogen, alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkylalkyl or -(CO)R3; Y1 represents hydroxyl, alkoxyalkyloxy, trialkylsilyloxy or -O(CO)R3; Y2 represents hydrogen or alkyl; or Y1 and Y2 together form =O. The compound has excellent control effects on pests such as Myzus persicae, Lygus lineolaris, Rhopalosiphum maidis and Bemisia tabaci.

Mobile or stationary air filter (L) or room fan (RL) according to Figure 1, comprising an outer wall (5), a (2) for generating an airflow (3) which is guided through an air filter material (1.1), an air inlet (2.1) and an air outlet (2.2), wherein the air filter material (1.1) contains poly(styrenesulfonic acid) (sulfonic acid biocide) (1.3) cross-linked with divinylbenzene and / or an acidic salt (1.3.1) (sulfonic acid biocide salt) of the sulfonic acid biocide (1.3) with biocidal cations, wherein the sulfonic acid biocide (1.3) and / or sulfonic acid biocide salt (1.3.1)(i) are positively and / or materially bonded to and / or in inert carriers and, in the fixed state, are in direct contact with carrier materials (1.1.7) on and / or in which biocidal Metal microparticles of a mean particle size d50 of 0.1 µm to <1,000 µm are fixed, and / or (ii) with carrier materials (1.1.7) on and / or in which biocidal metal microparticles of a mean particle size d50 of 0.1 µm to <1.000 µm are fixed, are mixed; its use and methods for the production and environmentally friendly disposal of air filter materials (1.1).

The invention discloses application of ursolic acid in resisting fish ichthyophthiriasis. The ursolic acid has a remarkable killing effect on ichthyophthirius multifilis in an in-vitro stage, and the 4-hour half effective insecticidal concentration (4h-EC50) of the ursolic acid on a grazing body is 0.3774 mg / L; and the 22-hour half effective insecticidal concentration (22h-EC 50) on the capsule is 4.931 mg / L. An acute toxicity test shows that the 96-hour median lethal concentration (96h-LC50) of ursolic acid to goldfish is 9.358 mg / L, the therapeutic index (TI = 96h-LC50 / 4h-EC50) is up to 24.8, and the safety of ursolic acid is remarkably superior to that of a traditional medicine. Ursolic acid used in the invention is a plant-derived active component, has the characteristics of high environmental compatibility and low biological accumulation, meets the development requirements of green fishery, and has an industrialization basis for being developed into eco-friendly aquatic products.

The invention relates to the technical field of green prevention and treatment of dendroctonus valerieus, in particular to a dendroctonus valerieus repellent as well as a preparation method and application thereof. The repelling component comprises fenchone. The fenchone is found to have an obvious repelling effect on the dendroctonus resurus, and meanwhile, the fenchone can be used as a repellent for the dendroctonus resurus, and the dendroctonus resurus can be repelled in production to protect an ecological system of a pine forest. The repellent has the advantages of good repelling effect, stability, environmental friendliness and wide industrialization prospect.

The invention relates to a pesticide residue detection test strip as well as a preparation method and application thereof, in particular to a rapid detection technology based on an enzyme inhibition method and a chitosan non-woven fabric carrier. The test strip can specifically detect organophosphorus and carbamate pesticides such as trichlorfon, malathion and phoxim through the enzyme activity inhibition principle, the detection limit of the pesticides such as phoxim is as low as 0.1 mg / kg, the developing intensity is in negative correlation with the pesticide concentration, and semi-quantitative judgment can be achieved. The preparation process is simple, the chitosan non-woven fabric is adopted as a fixed carrier, the material is environment-friendly and degradable, the enzyme activity recovery rate reaches 90%, the stability is excellent (the enzyme activity recovery rate can be preserved for 60 days at the temperature of 4 DEG C in a dark place), sample pretreatment is not needed in detection operation, a result can be obtained at the normal temperature for 15 min, the stability and repeatability are good, and the problems that a traditional instrument is high in detection cost and long in time consumption are solved; the method has a remarkable basic popularization value.

The invention provides a method for detecting free amino acids in camellia oleosa seed oil, and establishes a method for detecting the free amino acids in the camellia oleosa seed oil based on ultra-high performance liquid chromatography-tandem mass spectrometry (UPLC-MS / MS), which comprises the following steps: pre-treating various amino acids in the camellia oleosa seed oil by using a non-derivation method; the problems of complicated operation, impurity interference and the like caused by derivatization are avoided, the extraction solvent is environment-friendly and economical, the extraction efficiency is high, and the pretreatment time is greatly shortened; then selecting a proper chromatographic column and a mobile phase, separating a plurality of free amino acids under the condition of not introducing excessive derivatization agents and ion pair reagents, and controlling the collection time to be 12 minutes. The method for detecting the free amino acids in the camellia oleosa seed oil has the characteristics of no need of derivatization treatment, simplicity and convenience in operation, high detection efficiency and good sensitivity and accuracy, and can effectively separate and detect 14 free amino acids such as alanine, phenylalanine and aspartic acid in the camellia oleosa seed oil.

The invention discloses a composite curcumin nano pesticide and a preparation method and application thereof.The nano pesticide comprises a carrier and curcumin loaded on the carrier, the carrier is polydopamine-sodium lignin sulfonate, and the polydopamine-sodium lignin sulfonate is formed by polymerizing dopamine hydrochloride on the surface of lignin; the preparation method comprises the following steps: preparing a curcumin solution, adding the polydopamine-sodium lignin sulfonate powder, fully dispersing, slowly stirring under a dark condition until a yellow solution becomes dark red, and removing a solvent to obtain the polydopamine-sodium lignin sulfonate-curcumin. The nano pesticide provided by the invention takes polydopamine-sodium lignin sulfonate as a carrier, so that the drug has pH and photo-thermal response controlled release function, burst release of curcumin is avoided, and the stability and bioavailability of curcumin are improved.

The invention discloses a preparation method of deer spleen aminopeptide powder in the field of bioactive substance extraction and functional material compositing, and the performance of the deer spleen aminopeptide powder is improved by compositing a multi-stage functional modified material and deer spleen aminopeptide. The preparation method comprises the following steps: cleaning, homogenizing and crushing fresh deer spleen, extracting with a phosphate buffer solution, adjusting the pH value, carrying out enzymolysis, inactivating enzyme, and treating with an ultrafiltration membrane and a nanofiltration membrane in a specific molecular weight range to obtain a concentrated solution; and mixing the concentrated solution with a multi-stage functional modified material under proper conditions, sterilizing, pre-freezing, and freeze-drying to obtain the deer spleen aminopeptide powder. Wherein the modified material is constructed through quaternization modification, nanopore loading, enzyme inhibitor coupling and targeting ligand modification, and has the functions of charge repulsion, steric hindrance, enzyme inhibition and targeting recognition. The deer spleen aminopeptide powder prepared by the invention has high stability and good bioavailability, and is suitable for functional food or health care products.

The invention belongs to the technical field of pesticide suspending agents, and particularly discloses a micro-capsule suspension-suspending agent containing chlorine fluorine and clothianidin and a preparation method of the micro-capsule suspension-suspending agent. The microcapsule suspension-suspending agent is prepared from the following raw materials: 11 to 13 percent of lambda-cyhalothrin, 12 to 14 percent of clothianidin, 9.20 to 9.60 percent of a solvent, 3.25 to 3.45 percent of a wall material I, 0.35 to 0.50 percent of protective glue, 2.13 to 2.33 percent of an emulsifier, 1.24 to 1.45 percent of a dispersing agent I, 0.24 to 0.45 percent of a wall material II, 3.90 to 4.10 percent of a dispersing agent II, 2.92 to 3.12 percent of an anti-freezing agent, 0.03 to 0.07 percent of a thickening agent I, 0.45 to 0.55 percent of a thickening agent II, 0.46 to 0.52 percent of a preservative and the balance of water. The microcapsule suspension-suspending agent prepared in the invention has good stability in the storage process, the slow release of effective components is controlled, and the lasting period is prolonged.

Compounds of formula I (Formula I),where the substituents R1 through R5 are defined herein, and agrochemically acceptable salts, stereoisomers, enantiomers, tautomers and N-oxides of the compounds of Formula (I). In addition, methods and uses of compounds of Formula I as, for example, insecticides. Compositions having compounds of Formula (I) and their uses in controlling insects, particularly in crops of useful plants. Methods and intermediates related to the synthesis of compounds of Formula (I).

The invention relates to the technical field of microbial treatment of antibiotic pollution, and discloses an antibiotic degrading bacterium with salt tolerance and capable of degrading sulfamethoxazole at low temperature and application, the strain degrades SMX in a wide temperature range of 10-40 DEG C, the degradation rate of 20mg / L SMX at 10-35 DEG C within 64 hours is greater than 70%, and the degradation rate of 20mg / L SMX at 20-30 DEG C reaches 100%; at the low temperature of 10 DEG C, low-concentration SMX is obviously degraded, and the SMX with the concentration of 5 mg / L can be completely degraded within 16 hours; the MJ2 can still effectively degrade SMX under the harsh conditions that the temperature is low and SMX serves as the unique carbon and nitrogen source, the degradation rate reaches 100% after 66h at the concentration of 5 mg / L, and it is proved that the MJ2 has the unique oligotrophic adaptability. Salinity tests show that the degradation rate of MJ2 to 20 mg / L SMX within 48 hours under the 0.1-2% NaCl concentration is 100%, the degradation rate is still kept at 50% even under the stress of 3% high salt, and remarkable salt tolerance is also shown. In conclusion, the strain MJ2 integrates wide temperature range adaptability, low-temperature high efficiency, oligotrophic tolerance and high salt stability, and has great application value in sulfonamide antibiotic pollution remediation in a complex environment.

The invention belongs to the technical field of agricultural compositions, and particularly relates to a composition for preventing and treating papaya spider mites. The active ingredients of the composition are hexythiazox and quercetin, the mass ratio of hexythiazox to quercetin is 1: (0.5-20), preferably 1: (7.5-12.5), and an indoor toxicity determination test shows that the composition has a remarkable synergistic effect on tetranychus urticae within the ratio range. The invention also provides a water emulsion, a suspending agent, missible oil and other pesticide preparations containing the composition. Field efficacy tests prove that the composition provided by the invention has a good control effect on tetranychus urticae on papaya, is long in lasting period, and can effectively slow down the development of pest drug resistance. The invention provides a novel scheme with high efficiency and low dosage for controlling the carica papaya spider mites.

The invention provides an m-diamide compound as well as a preparation method and application thereof. The m-diamide compound is a compound represented by a formula I, or a stereoisomer, a tautomer, an isotope derivative and a pesticide acceptable salt thereof. The m-diamide compound disclosed by the invention has high insecticidal activity, still has a good insecticidal effect under a low dosage, and is more beneficial to environmental protection; moreover, the insecticidal composition has excellent persistence and quick-acting property on killing pests, and does not easily generate cross resistance with existing m-diamide compounds; the plant safety is realized.

The present disclosure relates to liquid (e.g., water-soluble) compositions comprising antimethanogenic compounds, and methods of administering the same to reduce enteric methane emissions from ruminant animals, and / or improve feed-efficiency. Certain disclosed compositions exhibit improved rapid effect over prior art compositions. The disclosure further relates to methods of concentrating antimethanogenic compounds, extracting antimethanogenic compounds, and methods of increasing the bioavailability of antimethanogenic compounds.

Compounds of the formula (I) wherein Q is as defined in claim 1. Furthermore, the present invention relates to agrochemical compositions which comprise compounds of formula (I), to preparation of these compositions, and to the use of the compounds or compositions in agriculture or horticulture for combating, preventing or controlling animal pests, including arthropods and in particular insects, molluscs, nematodes or representatives of the order Acarina.

The invention relates to the technical field of pesticides, in particular to a pesticide composition, application thereof and a pesticide preparation. The pesticide composition comprises a first effective component and a second effective component, the first effective component is 1, 8-cineole, and the second effective component comprises at least one of flonicamid, cyantraniliprole, nitenpyram, flubendiamide, spirotetramat, pyriproxyfen, pymetrozine, dinotefuran and sulfoxaflor. The mass ratio of the first effective component to the second effective component is (50: 1)-(1: 100). Through the synergistic interaction of the first effective component and the second effective component, the prevention and treatment effect is remarkably improved, the prevention and treatment spectrum is expanded, and the field dosage can be greatly reduced; specifically, leaf back bemisia tabaci and trialeurodes vaporariorum can be well controlled, the control effect on bemisia tabaci, trialeurodes vaporariorum, thrips and the like is improved, and the application prospect is good.

The invention relates to the technical field of chemical fertilizer preparation, and discloses a special synergistic pesticide fertilizer for a ratoon cane seedling stage, a preparation method and application thereof, the pesticide fertilizer adopts a core-shell layered structure, and comprises a core fertilizer layer, a pesticide layer and a resin coating layer from inside to outside in sequence; the medical fertilizer comprises the following components: 20-40% of an organic fertilizer; 20%-40% of inorganic nitrogen fertilizer; 5%-20% of a medium element fertilizer; 0.1%-2.5% of an insecticide; 0.1%-2.5% of a bactericide; 0.5%-5% of a composite slow release agent; 0.4%-2% of a resin coating material; and the balance of filler. By optimizing a formula and a preparation process, synergistic release of fertilizer nutrients and pesticide active ingredients is realized, nutrient requirements and disease and pest control requirements of ratoon sugarcanes in the seedling stage are met, the budding rate is remarkably increased, the withered seedling rate is reduced, and yield and income are finally increased; the stability and effectiveness of each component in the pesticide fertilizer can be effectively ensured; through precise application, multiple effects of the pesticide fertilizer are exerted to the maximum extent, and a standardized technical scheme is provided for seedling management of ratoon sugarcanes.

The invention discloses an insect antibacterial peptide nutrient solution as well as a preparation method and application thereof, and belongs to the technical field of biology. Insect protein (fly maggot powder / hermetia illucens) and plant fiber (bran) are subjected to enzymolysis and then subjected to a pH gradient chelation process (5.0-7.0-8.5), metal ions (Fe < 2 + > / Mn < 2 + > / Zn < 2 + >) are added in stages for chelation, the chelation degree is larger than or equal to 91.4%, lentinan and alginate oligosaccharide are added for synergistic interaction, and finally the insect antibacterial peptide nutrient solution is obtained. Experiments prove that after the insect antibacterial peptide nutrient solution prepared by the invention is used for carrying out root irrigation treatment on plants, tomato yellow leaf curl virus or tomato spotted wilt virus can be remarkably prevented and treated, and the insect antibacterial peptide nutrient solution has high efficiency and persistence and conforms to the development direction of green plant protection.

The invention discloses a potato high-yield disease-resistant controlled-release special fertilizer and application thereof, and relates to the technical field of fertilizer production. The high-yield disease-resistant controlled-release fertilizer special for the potatoes is prepared by adopting synergistic controlled-release urea coated with double-layer microbial agents and a controlled-release potassium-magnesium fertilizer as raw materials, wherein the synergistic controlled-release urea coated with the double-layer microbial agents is prepared by performing double-layer coating on urea through a micro-capsule loaded microbial agent. The fertilizer prepared by the invention has an optimized nutrient proportion of high potassium, medium and high nitrogen and low phosphorus, and the nutrient type and dosage accord with the nutrient requirement rule of the potatoes on macroelements. Meanwhile, the controlled release effect is realized by adopting a modified sulfur coating technology, so that the nutrient requirements of the potatoes in the key growth period are met. Through the comprehensive nutrient controlled release and inner and outer film layer fungicide loading technology, the nutrient utilization efficiency can be greatly improved, the potassium and magnesium absorption rate and the plant resistance of the potatoes are improved, diseases are reduced, the yield of the potatoes per unit area is remarkably improved, and the fertilization amount and the fertilization frequency can be reduced.

To provide protective clothing that can protect the body when attacked by a bear and repel the bear. [Solution] Protective clothing worn to repel bear attacks comprises a protective fabric 1 sandwiched between a surface fabric 2 and a backing fabric 3. The protective fabric 1 comprises a chemical-containing layer 11 capable of releasing a chemical to repel bears, and a protective layer 12 for physical protection from bear attacks. The chemical used to repel bears is capsaicin, derived from chili peppers. When a strong force is applied to the human body by a bear attack, physical damage to the chemical-containing layer 11 causes the chemical to be released, allowing the bear to repel. Furthermore, the protective layer 12 cushions the impact on the human body, making the garment effective in protecting the human body from bear attacks.

The invention relates to the technical field of organic synthesis, in particular to 4-chloro-1-methyl-6H-heterochromene [3, 4-c] pyridine as well as a synthesis method and application of the 4-chloro-1-methyl-6H-heterochromene [3, 4-c] pyridine. The synthesis method comprises the following steps: (1) synthesizing 2-chloro-3-fluoro-4-iodine-5-methylpyridine from 2-chloro-3-fluoro-5-methylpyridine and an iodine elementary substance to obtain 2-chloro-3-fluoro-4-iodine-5-methylpyridine; (2) synthesizing 2-(2-chloro-3-fluoro-5-methylpyridine-4-yl) benzaldehyde from the 2-chloro-3-fluoro-4-iodo-5-methylpyridine, the 1, 1-bis (diphenylphosphine) ferrocene palladium dichloride, the tripotassium phosphate and the (2-formyl phenyl) boric acid, and further synthesizing the 2-(2-chloro-3-fluoro-5-methylpyridine-4-yl) benzaldehyde from the 2-chloro-3-fluoro-4-iodo-5-methylpyridine and the 1, 1-bis (diphenylphosphine) ferrocene palladium dichloride. And (3) synthesizing the 4-chloro-1-methyl-6H-heterochromene [3, 4-c] pyridine by using the 2-(2-chloro-3-fluoro-5-methylpyridine-4-yl) benzaldehyde and sodium tert-butoxide. The 4-chloro-1-methyl-6H-heterochromene [3, 4-c] pyridine compound constructed by the invention can be used for detecting the content of pesticide residue glyphosate.

The invention relates to a diptera adult insecticide, which contains an insecticidal functional component n-butyl alcohol. According to the invention, n-butyl alcohol which has an obvious poisoning effect on the adult cucurbita petiolatus is separated from a metabolite of a bacillus thuringiensis XLB2910 strain, and 2, 3, 5-trimethylpyrazine and benzothiazole which have an obvious poisoning effect on the adult aedes albopictus are also separated from the metabolite of the bacillus thuringiensis XLB2910 strain. Through poisoning concentration analysis of different components and a compound combination experiment, a series of pesticides for adult cucurbita petioles and adult aedes albopictus are formed, the prepared compound pesticide for cucurbita petioles comprises 2.5%-10% of 2, 3, 5-trimethylpyrazine, 2%-10% of benzothiazole and 5%-10% of n-butyl alcohol, and the prepared compound pesticide for aedes albopictus comprises 2.5%-10% of 2, 3, 5-trimethylpyrazine, 2%-10% of benzothiazole and 5%-10% of n-butyl alcohol. The composition comprises 0.5%-3% of 1, 3, 5-trimethylpyrazine, 0.05%-1.5% of benzothiazole and 1%-3% of n-butyl alcohol. The compound insecticide has a good insecticidal effect on cucurbita petiolatus adults and aedes albopictus adults, and is wide in raw material source and environment-friendly.

The invention relates to the technical field of agricultural plant disease control, and particularly discloses a biological and chemical compound bactericide and application thereof. The biological and chemical compound bactericide comprises a bacterial solution of a biocontrol strain bacillus velezensis LHN1 and a chemical bactericide, the biocontrol strain bacillus velezensis LHN1 is preserved in Guangdong Microbial Culture Collection Center, and the preservation number is GDMCC No: 63550; the chemical bactericide is selected from at least one of prochloraz, pyraclostrobin or tebuconazole; in the compound bactericide, the volume ratio of the LHN1 bacterial liquid to the chemical bactericide is (1: 4)-(4: 1). Through the synergistic effect of biological prevention and control and chemical prevention and control, the problems that a single chemical bactericide pollutes the environment and the single biological prevention and control effect is unstable are solved, the prevention effect in a pot experiment reaches up to 83.99%, meanwhile, the dosage of chemical agents is reduced by 30%-50%, and the method has the advantages of being efficient, low in toxicity and low in cost and is suitable for root rot prevention and control in large-scale planting of rhizoma polygonati.

The invention discloses application of cordyceps javanica Bd01 and a dispersible oil suspending agent thereof to prevention and control of spodoptera frugiperda, and relates to the technical field of biology. The research finds that the cordyceps javanica Bd01 has a strong infection lethal effect on larvae of spodoptera frugiperda at all ages, the pupation rate and eclosion rate of the larvae can be remarkably reduced, and the breeding cycle of pests can be effectively blocked. The invention further develops a dispersible oil suspending agent, and the suspending rate is effectively improved through formula optimization. The dosage form takes soybean oil as a dispersion medium, does not contain harmful solvents such as methylbenzene, is free of dust pollution and is friendly to operators and the environment, and ascorbic acid is added to improve the ultraviolet resistance of spores and prolong the effective period of the pesticide effect. In addition, the preparation also has a certain control effect on caffeinidae, is wide in application scene, provides a new scheme for green control of spodoptera frugiperda, solves the problems of chemical pesticide resistance and residue, and accords with the development requirements of green agriculture.

The invention belongs to the technical field of antibiotic pollutant degradation, and discloses a method for degrading antibiotic pollutants by using boron-carbon co-regulated nanoscale zero-valent iron as an activating agent, which comprises the following steps: step 1, synthesizing carbon-coated nanoscale zero-valent iron, marked as Fe0-C, through a hydrothermal method and a carbothermic method; and step 2, mixing the Fe < 0 >-C obtained in the step 1 with crystal boron, adding the mixture into sewage containing antibiotic pollutants, and then adding persulfate as an oxidizing agent to degrade the antibiotic pollutants. A boron-carbon co-regulation method is adopted to realize the passivation resistance of the nano zero-valent iron in the whole process from preparation, storage to application, and the nano zero-valent iron is applied to the process of activating persulfate to degrade tetracycline.

The invention belongs to the technical field of organic synthetic chemistry and pesticide science, and particularly relates to an indole-containing amide derivative as well as a preparation method and application thereof, and the indole-containing amide derivative has a structure as shown in a formula I or a formula II, through an active substructure splicing strategy, indole is used as a parent skeleton, amido bonds are ingeniously introduced for structural diversity optimization and modification, active functional groups such as methoxyamine are further introduced, and a series of indole amide derivatives with novel structures are designed and synthesized. Through determination, the screened series of compounds show good antibacterial activity, and a plurality of compounds show excellent prevention and treatment effects on various important crop diseases.

The invention belongs to the technical field of pesticides and plant disease control, and provides an antifungal phenothiazine derivative which can inhibit various fungal diseases on rice and tobacco. The derivative can also be compounded with triazole or fluazinam to prevent and treat fungal diseases of rice and tobacco, and has a good development prospect.

Described herein are long-acting injectable formulations for the treatment or prevention of a parasitic infestation or infection in an animal. The formulation contains a parasiticidal isoxazoline active agent; and castor oil or a combination of castor oil and a second natural oil. The amount of castor oil in the formulation or the combination of castor oil and the second natural oil is at least 40% (w / w). The formulation can be in the form of a solution or a suspension, and physically stable at standard ambient temperature and pressure for at least 1 month. Typically, the formulation is at least 80% effective at treating or preventing infestation by fleas and / or ticks for at least 6 months following a single administration to the animal.

Compounds of Formula (I) wherein the substituents are as defined in claim 1. The invention further relates to herbicidal compositions which comprise a compound of Formula (I) and to the use of compounds of Formula (I) for controlling weeds, in particular in crops of useful plants.