1862 results about "Thiazole" patented technology

The invention discloses a method for detecting glufosinate-ammonium residues in coffee in dual modes of colorimetry and chemiluminescence, and belongs to the technical field of chemical analysis and detection.The method comprises the steps that Schiff base formed by 4-aminoantipyrine and glutaraldehyde serves as a complexing agent of Cu < 2 + >, and then a copper-doped carbon dot Cu-CDs nano-enzyme is prepared through microwave digestion; according to the present invention, the Cu-CDs nano-enzyme has excellent peroxidase-like activity, can oxidize the colorless 2, 2 '-biazo-bis-3-ethylbenzothiazoline-6-sulfonic acid into the blue-green oxidized ABTS, and can improve the chemiluminescence intensity of the reaction of N-(4-aminobutyl)-N-ethylisoluminol and H2O2 by nearly 100 times when the Cu-CDs nano-enzyme is used as the chemiluminescence catalyst; based on the inhibition effect of glufosinate-ammonium on the activity of Cu-CDs POD, a sensitive and rapid colorimetric and chemiluminescence two-channel GM detection technology is developed, and the method has potential application value in the aspect of coffee safety monitoring.

The application relates to a compound of formula (I) containing a thiazole ring, an indazol ring and a 6,7-dihydro-5H-pyrrolo[1,2-c]imidazole ring system, to pharmaceutical compositions containing it and its medical use. The compounds are described as selective allosteric inhibitors of T790M / L858R, T790M / L858R / C797S, L858R, L858R / C797S containing EGFR mutants and thus useful for the treatment of cancer, in particular non-small cell lung cancer.

The invention relates to the field of coatings, and discloses an outer wall light radiation heat preservation and heat insulation decorative sheet and a preparation method thereof.A radiation refrigeration layer on the surface of the outer wall light radiation heat preservation and heat insulation decorative sheet comprises modified acrylate resin, silicon dioxide, ground calcium carbonate, talcum powder, modified hollow glass beads and auxiliaries; the modified acrylate resin is prepared by copolymerizing perfluorooctyl ethyl acrylate, methyl methacrylate, modified isocyano ethyl methacrylate and vinyltriethoxysilane, and the modified isocyano ethyl methacrylate is prepared by using salicylaldehyde and benzothiazole-2-formaldehyde as well as 1, 2, 4-trimethyl-1, 3-pentanediol monoisobutyrate as an initiator and using 2, 3, 4-trimethyl-1, 3-pentanediol monoisobutyrate as an initiator. The preparation method comprises the following steps: reacting amino groups at two ends of 1, 5-naphthylenediamine with DOPO, carrying out nucleophilic addition reaction with DOPO, and grafting with isocyano ethyl methacrylate. The modified hollow glass beads are prepared by using tetrabutyl titanate as a titanium source through a sol-gel method, and the prepared radiation refrigeration layer has the super-amphiphobic self-cleaning effect, the radiation refrigeration effect is good, and meanwhile the flame retardant property and the antibacterial effect are excellent.

The invention discloses a sunlight response high-strength self-repairing polyurethane material and a preparation method thereof, and belongs to the technical field of self-repairing materials, the sunlight response high-strength self-repairing polyurethane material is obtained by coordinating polyurethane containing an azothiazole structure and metal ions according to a certain proportion, the polyurethane containing the azothiazole structure is prepared by stirring diisocyanate, diol containing the azothiazole structure, long-chain diol and aminophenylboronic acid according to a certain proportion in N, N-dimethylformamide at room temperature to react for 5 hours. According to the invention, a photoactive azothiazole structure is introduced into polyurethane, and reversible metal coordination bonds are formed by the azothiazole structure and metal ions, so that rapid sunlight response self-repairing of the polyurethane material is realized. The self-repairing efficiency of the prepared photoresponse self-repairing polyurethane material is 95.1% after the photoresponse self-repairing polyurethane material is irradiated by sunlight for 2 h, and the photoresponse self-repairing polyurethane material has rapid photoresponse self-repairing performance and has wide application prospects in the fields of self-repairing coatings, intelligent coatings and anti-corrosion coatings.

A corrosion inhibitor composition includes a fatty acid ethoxylate, a thiourea, an arylthiourea, a thiazole, and two or more solvents. A metal article in contact with the composition has a corrosion rate of about 25 to about 45 mils penetration per year (mpy), as determined by an ASTM G111 standard test method. A method for inhibiting corrosion of a metal in contact with a corrosive fluid.

The invention relates to a composite reverse osmosis membrane acidic cleaning agent, a preparation method and a cleaning process thereof, and belongs to the technical field of environment-friendly water treatment. The cleaning agent comprises the following components in percentage by mass: 4-8% of inorganic acid, 20-40% of organic acid, 1-3% of a surfactant, 0.5-1% of a chelating agent, 0.5-1% of a compound corrosion inhibitor and the balance of deionized water. The composite corrosion inhibitor is formed by compounding 2-mercaptobenzothiazole and the like according to a specific mass ratio, the molecular weight of polyaspartic acid is 5000, and the molar ratio of Zn to Mo in the zinc-molybdate compound is 2: 1. The preparation method comprises the following four steps: firstly preparing a compound corrosion inhibitor premix, then preparing an acidic base solution, and then sequentially adding the components to finally obtain the cleaning solution. According to the cleaning process, a cleaning agent and deionized water are mixed, the membrane flux recovery rate is larger than or equal to 85% through cleaning of a specific process, the reverse osmosis membrane can be effectively cleaned, and the performance of the reverse osmosis membrane can be recovered.

The invention discloses a photoelectric device, a preparation method thereof and a display device, and relates to the technical field of display. The photoelectric device comprises an anode, a functional layer and a cathode which are stacked. The material of the functional layer comprises a doped corrosion inhibitor, and / or a first corrosion inhibition layer is arranged between the anode and the functional layer, and the material of the first corrosion inhibition layer comprises a first interface corrosion inhibitor; the doping corrosion inhibitor and the first interface corrosion inhibitor respectively comprise one or more of a thiazole compound and a cyclic sulfydryl compound. The photoelectric device provided by the invention is good in corrosion resistance.

The invention provides a thiazolidinone compound and application thereof in preparation of drugs for resisting staphylococcus aureus infection. The molecular structural formula of the thiazolidinone compound is shown as a formula (1), a formula (2), a formula (3) or a formula (4). The technical scheme of the invention discloses several thiazolidinone compounds, which not only have an excellent bactericidal effect on staphylococcus aureus and can significantly inhibit the formation of a biofilm of staphylococcus aureus, but also have low cytotoxicity and hemolytic activity. According to the technical scheme, a certain foundation is laid for research and development of novel staphylococcus aureus biofilm infection resisting drugs, and the potential of thiazolidone derivatives for developing novel antibacterial agents for staphylococcus aureus related infection can be deeply known possibly.

The invention relates to solid compositions comprising {2-[3-cyclohexyl-3-(trans-4-propoxy-cyclohexyl)-ureido]-thiazol-5-ylsulfanyl}-acetic acid, and methods of making and using such solid compositions.

According to the method for recycling the waste lithium ion battery positive electrode material aluminum foil, double-bond addition is conducted on ureido of allylurea and maleimide, meanwhile, thiazolecarboxylic acid amino cyclization is conducted, ternary heterocyclic molecules containing ureido, thiazole rings and carboxyl are generated, S atoms, N atoms and O atoms form tridentate coordination sites, and the leaching rate of aluminum is increased.

The invention discloses a preparation method of a dotenorad key intermediate, and belongs to the technical field of compound synthesis. In the preparation method of the dotenorad key intermediate, provided by the invention, 2-aminothiophenol and formaldehyde are used as raw materials to carry out cyclization reaction to prepare a compound as shown in a formula 1, and then the compound as shown in the formula 1 and 3, 3, 3, 3, 3, 3, 3, 3, 3, 3, 3, 3, 3, 3, 3, 3, 3, 3, 3, 3, 3, 3, 3, 3, 3, 3, 3 According to the method, 3-(3, 5-dichloro-4-methoxybenzoyl chloride)-2, 3-dihydro-1, 3-benzothiazole is used as a raw material, an amidation reaction is carried out on 3, 5-dichloro-4-methoxybenzoyl chloride in an aqueous solution of an organic solvent, and the key intermediate 3-(3, 5-dichloro-4-methoxybenzoyl)-2, 3-dihydro-1, 3-benzothiazole of dotenorad can be effectively prepared; the obtained dotenorad key intermediate is relatively high in yield and purity; moreover, benzothiazoline which is widely used in the prior art does not need to be used in the preparation method, an activating agent or a solubilizer does not need to be used, the operation method is simple, reaction conditions are mild, and the method is suitable for actual industrial production.

The invention provides a D-A type organic fluorescent small molecule, a preparation method and application of the D-A type organic fluorescent small molecule in detection of nitrofuran antibiotics, and belongs to the technical field of fluorescent sensing. The D-A type organic fluorescent micromolecule is composed of 2-(2-aminophenyl) benzothiazole and an electron-donating group, the excitation spectrum of the D-A type organic fluorescent micromolecule is obviously overlapped with the absorption spectrum of nitrofuran antibiotics, and fluorescence quenching response can be shown through the inner filter effect; the trace nitrofuran antibiotics can be detected in a liquid phase in an ultrafast, high-sensitivity, excellent-selectivity and strong-anti-interference manner. According to the invention, a quantitative evaluation system can be constructed in combination with a smart phone, the RGB value of the image of the liquid-phase fluorescence sensor is output in real time, and rapid, accurate and visual quantitative detection of nitrofuran antibiotics in a real food sample or a water source is realized. In addition, the filter paper fluorescence sensor has the advantages of being portable and easy to prepare, and nitrofuran antibiotics can be rapidly identified on site in an actual scene.

The invention belongs to the technical field of anticorrosive coatings, and particularly relates to a high-temperature-resistant hydrophobic anticorrosive coating as well as a preparation method and application thereof. The invention provides a high-temperature-resistant hydrophobic anticorrosive coating, which is prepared from the following raw material components in parts by weight: 100 to 140 parts of epoxy resin; 3 to 7 parts of 2-benzothiazole thiosuccinic acid; 2 to 6 parts of hydrophobically modified ZIF-67 (at) MgAlCeFe-LDH (layered double hydroxide); 4-8 parts of a filler; 2-6 parts of a dispersant; 1-3 parts of a defoaming agent; 2-4 parts of a coalescing agent; 15-35 parts of a curing agent; 20 to 30 parts of water; and 10 to 20 parts of ethanol. The hydrophobic property of the coating can be improved by adding hydrophobic modified ZIF-67 (at) MgAlCeFe-LDH, and the corrosion resistance of the anticorrosive coating is remarkably improved by matching with 2-benzothiazole thiosuccinic acid and utilizing the interaction between the ZIF-67 (at) MgAlCeFe-LDH and the 2-benzothiazole thiosuccinic acid. The anti-corrosion coating prepared by the method has excellent corrosion resistance, hydrophobic performance and high temperature resistance.

The invention discloses a copper surface micro-etching coarsening solution for a fine circuit as well as a preparation method and application of the copper surface micro-etching coarsening solution, and relates to the technical field of printed circuit board manufacturing. The copper surface micro-etching coarsening solution for the fine circuit is prepared from, by mass concentration, 60 g / L to 100 g / L of sulfuric acid, 40 g / L to 60 g / L of hydrogen peroxide, 0.5 g / L to 2 g / L of zinc sulfate, 10 g / L to 30 g / L of copper ions, 0.5 g / L to 1 g / L of pyridine heterocycle-containing Schiff base, 10 g / L to 100 g / L of ethyl alcohol, 1 g / L to 3 g / L of 2-mercaptobenzothiazole, 1 g / L to 5 g / L of methionine and 1 g / L to 5 g / L of polyacrylamide. According to the copper surface micro-etching coarsening solution, the 2-mercaptobenzothiazole and the methionine in the copper surface micro-etching coarsening solution can enable the copper surface to form a honeycomb structure under the low micro-etching amount, the zinc sulfate and the pyridine heterocyclic ring-containing Schiff base can form a composite film layer with copper ions on the surface of the honeycomb structure, and the interlayer binding force is improved.

The invention discloses a preparation method of a 3-micron ultrathin lithium battery copper foil. The preparation method comprises the following steps: preparing a copper sulfate electrolyte; a wetting agent, a brightening agent and a high resistance agent are added into the copper sulfate electrolyte, the high resistance agent is at least one of thiazolidinethione, polyethyleneimine, 2-mercaptobenzimidazole and ethylene thiourea, and a mixed additive is formed; polishing and grinding a cathode roller by adopting a flying wing wheel, and carrying out electrolytic treatment on the mixed additive through the polished and ground cathode roller to obtain a first-stage copper foil; and the first-stage copper foil is placed in a nitrogen furnace to be subjected to annealing treatment, and the 3-micron ultrathin lithium battery copper foil is obtained. The invention aims to solve the technical problems that in the prior art, edge tearing, foil breaking, warping, dark appearance oxidation and the like are prone to occurring in the production process of the ultrathin copper foil, the tensile strength and the ductility are difficult to consider at the same time, and stable mass production of the 3-micron copper foil is still difficult.

The invention relates to the technical field of reverse osmosis membrane maintenance, in particular to a cleaning scale inhibitor special for a reverse osmosis membrane and application of the cleaning scale inhibitor. The cleaning scale inhibitor provided by the invention comprises an agent A, an agent B and an agent C, the agent A comprises the following components in percentage by mass: 10-20% of organic phosphonic acid, 10-20% of polycarboxylic acid polymer, 5-10% of sulfamic acid, 3-8% of sodium gluconate and the balance of water; the agent B comprises 8-15% of an isothiazolinone bactericide, 5-10% of a nonionic surfactant, 3-8% of a chlorine bactericide, 2-5% of sodium dodecyl benzene sulfonate and the balance of water; and the agent C comprises 10-20% of sodium polyacrylate, 8-15% of sodium hexametaphosphate, 5-10% of citric acid, 3-8% of silicate and the balance of water. The cleaning scale inhibitor provided by the invention has an efficient cleaning effect on various pollutants, is environment-friendly, and does not cause chemical damage to a reverse osmosis membrane.

The invention discloses a composite collecting agent and a preparation method and application thereof, and relates to the technical field of solid waste recycling. The composite collecting agent comprises a main agent, an auxiliary agent and a synergist, and the mass ratio of the main agent to the auxiliary agent is (3-1): (1-2). The mass of the synergist is 0.1%-2.5% of the total mass of the composite collecting agent; the structural formula of the main agent is as shown in formula (I): R-O-C (= S)-NH-R '(I); in the formula (I), R is alkyl, and R'is 3-chloro-1, 2-epoxypropane; the auxiliary agent is a mercaptobenzothiazole derivative. The thiocarbamate and the mercaptobenzothiazole derivative are compounded according to a specific proportion for the first time, a Zn-S shielding layer is destroyed through an intermolecular synergistic effect, and the silver recovery rate is increased; the preparation method is simple and easy to operate, facilitates reduction of the dosage of a single agent and reduces environmental pollution. The foam stability is improved, the flotation efficiency is improved, the selective collection efficiency of the silver-zinc ore is remarkably improved, and the flotation index is improved.

The invention relates to the technical field of soil improvement, and discloses a soil improvement repairing agent and a preparation method thereof. The preparation method comprises the following steps: adding biochar, modified eugenol, modified benzothiazolyl pyridine, bacillus licheniformis and diatomite into a mixer, mixing and stirring, extruding and granulating in a granulator, and drying to obtain the soil improvement repairing agent. Eugenol can destroy a membrane structure and denature protein, so that a bacteriostatic effect is achieved, and a healthy soil microenvironment is provided for crops; the quaternary ammonium salt can destroy the membrane structure of pathogenic microorganisms, plays a role in killing the microorganisms, can improve the antibacterial effect of the remediation agent, and prevents and treats spread diseases of soil; nitrogen atoms and sulfur atoms in benzothiazolyl pyridine molecules can coordinate with free heavy metal ions in the soil, the heavy metal adsorption effect of the remediation agent is improved, the production value of the soil is gradually restored, meanwhile, boric acid capable of being absorbed by plants can be released through hydrolysis of pinacol ester, and the fertility of the soil is improved.

The present invention belongs to the technical field of flame-retardant epoxy resin materials, specifically DOPO-based triazine-bridged thiazole flame-retardant epoxy resin and a preparation method thereof, wherein the preparation method comprises: 1) reacting a nitrogen-containing five-membered heterocycle or a derivative thereof with p-hydroxybenzaldehyde to obtain an intermediate product I; 2) adding DOPO and a catalyst to the intermediate product I and reacting for 12 hours to obtain an intermediate product II; 3) reacting the intermediate product II with cyanuric chloride to obtain a DOPO-based triazine-bridged thiazole flame retardant; 4) uniformly mixing the obtained flame retardant with a bisphenol A epoxy resin; adding 4,4'-diaminodiphenylmethane after the temperature of the mixed liquid drops to 90°C, and finally obtaining a DOPO-based triazine-bridged thiazole flame-retardant epoxy resin through a thermal curing reaction. Due to the introduction of the DOPO-based triazine-bridged thiazole flame retardant, the epoxy resin material of the present invention has excellent flame retardant properties and mechanical properties.

The invention discloses a thiazole-linked covalent organic framework carbon nanomaterial compound as well as a preparation method and application thereof. The preparation method comprises the following steps: adding 4, 4 ', 4'-tetramethyl-4, 4 ', 4'-tetramethyl-4, 4 '-tetramethyl-4, 4'-tetramethyl-4, 4 '- The preparation method comprises the following steps: dissolving 4, 4 ', 4' '-(1, 3, 5-triazine-2, 4, 6-triyl) triphenylamine, 4, 4', 4 ''-(1, 3, 5-triazine-2, 4, 6-triyl) tribenzaldehyde, elemental sulfur and an amino-modified carbon nanomaterial in a solvent, reacting under the action of a catalyst, and purifying after the reaction to obtain the compound. The compound has high chemical stability, high crystallinity and excellent conductivity, and shows excellent rate capability and long cycle stability in a lithium ion battery. The invention provides a new thought for design and preparation of a high-performance energy storage electrode material.

The invention relates to the technical field of agricultural protection, in particular to an amide thiazole compound as well as a preparation method and application thereof. The amide nitrothiazole compound shown in the formula (1) is provided by carrying out proper structural modification on nitazoxanide, and the compound has good biological activity, can be applied to prevention and treatment of cryptosporidiosis and has a certain inhibition effect on florae such as rice streak, rice bacterial leaf blight, rice ralstonia solanacearum, cabbage soft rot and citrus ulcer. Formula (1): # imgabs0 #

The invention belongs to the technical field of drug development, and particularly relates to application of 2-fluoro-N-(2-(4-methyl-2-(m-tolyl) thiazole-5-yl) ethyl) benzenesulfonamide in preparation of drugs for treating nervous system diseases. The invention aims to provide a medicine which has small toxic and side effects and can target SLC11A2 to treat or improve nerve cell injury. According to the technical scheme, the invention relates to application of 2-fluoro-N-(2-(4-methyl-2-(m-tolyl) thiazole-5-yl) ethyl) benzenesulfonamide in preparation of a medicine for treating nervous system diseases. It is proved that the compound 2-fluoro-N-(2-(4-methyl-2-(m-tolyl) thiazole-5-yl) ethyl) benzenesulfonamide is small in toxic and side effect, and nerve cell damage can be protected or improved by targeting SLC11A2; and a new choice is provided for treating or improving nerve cell injury.

The present disclosure relates to the field of molecules having pesticidal utility on pests in Phyla Arthropoda, Mollusca and Nematoda, methods of producing such molecules, intermediates used in such methods, and methods of using such pesticidal compositions against such pests. These pesticidal compositions can be used, for example, as acaricides, insecticides, acaricides, molluscicides, and nematicides.

The present invention provides an industrial hose which is excellent in terms of heat resistance and adhesion between a plated wire layer 4 and an intermediate rubber layer 3.　This industrial hose includes a layer structure in which an inner surface rubber layer 1, an organic fiber layer 2, an intermediate rubber layer 3, and a plated wire layer 4 are stacked in this order. The inner surface rubber layer 1 is formed of a rubber composition that contains components (A)-(D). The total content (B + C) of the component (B) and the component (C) is 0.8-2.2 parts by mass with respect to 100 parts by mass of the component (A), and the mass ratio (B / C) of the component (B) to the component (C) is 1.8-18. (A) a rubber component which contains an acrylonitrile butadiene rubber. (B) at least one of a sulfenamide vulcanization accelerator and a thiazole vulcanization accelerator. (C) thiuram vulcanization accelerator. (D) N-phenyl-N-(trichloromethylthio)benzenesulfonamide.

The invention discloses a lead-free phosphorus chemical nickel plating solution, and relates to the field of chemical nickel plating, and the lead-free phosphorus chemical nickel plating solution comprises the following components: 6-10 g / L of nickel salt, 5-10 g / L of a complexing agent, 1-5 g / L of a brightener, 5-12 g / L of a reducing agent, 0.6-0.9 g / L of a composite stabilizer, 2-10 g / L of a plating starting agent, 0.1-0.6 g / L of a hydrogen evolution preventing agent and 30-60 mg / L of a surfactant. The adopted plating starting agent is high in decomposition capacity, after the service cycle is increased to 4 MTO, the problem that decomposition products are accumulatively increased to a certain degree to cause blackening of a plating layer can be relieved, 5-6 MTO can be achieved, meanwhile, the adopted composite stabilizer is a composition composed of an aminopyrrole carboxylic ester compound and an aminothiazole carboxylic ester compound, and the composite stabilizer has the beneficial effects of being environmentally friendly and free of pollution. The stability of traditional elements such as lead and cadmium can be improved, and the problem that the service cycle of stabilizers such as benzotriazole or sodium thiosulfate is short can be solved.

The invention discloses a copper-titanium etching solution and a preparation method thereof, and belongs to the technical field of etching solution preparation. The etching solution is prepared from the following components in percentage by mass: 4.5-7.5% of potassium peroxymonosulfate composite salt, 1.2-2.8% of sodium percarbonate, 1.2-2.8% of benzotriazole-2, 3, 4-triazole-2, 3, 4-triazole-2, 3, 4-triazole-2, 3, 4-triazole-2, 3- The cleaning agent is prepared from the following components in percentage by weight: 1.2%-1.8% of 1, 3-dicarboxylic acid, 0.3%-0.8% of 5-aminotetrazole, 0.15%-0.45% of ethylenediamine tetraacetic acid tetrasodium salt, 0.15%-0.45% of hydroxyethylidene diphosphonic acid, 0.15%-0.45% of cocamidopropyl betaine, 0.3%-0.8% of benzotriazole, 0.15%-0.45% of 2-mercaptobenzothiazole, 0.02%-0.08% of poly-N-isopropylacrylamide, 0.7%-1.8% of potassium perchlorate and the balance of ultrapure water. According to the etching solution, the copper-titanium etching rate can be accurately regulated and controlled, back cutting and titanium residues are effectively inhibited, the stability of the etching solution is improved, and the service life of the etching solution is prolonged.

The invention discloses a continuous reaction device and method for producing 2-amino-4-methylbenzothiazole, and belongs to the technical field of compound production. The invention relates to a continuous reaction device for producing 2-amino-4-methylbenzothiazole, which comprises a first-stage reaction kettle and further comprises a stirring mechanism arranged in the first-stage reaction kettle and used for stirring chlorine and a mixed solution in the first-stage reaction kettle; the driving mechanism is arranged at the top of the first-stage reaction kettle and is used for driving the stirring mechanism to perform stirring action in the first-stage reaction kettle; the chlorine injection mechanism is connected with the stirring mechanism; the air exhaust mechanism is arranged at the top of the first-stage reaction kettle and is connected with the driving mechanism; the multistage reaction kettles are adopted for continuous operation to eliminate downtime, so that the problem of low production efficiency caused by repeated heating and cooling due to the use of intermittent reaction kettles in the traditional process is solved, the chlorine utilization rate is improved, and the production and processing cost is effectively reduced.

The invention discloses a sulfanilamide thiazolyl resorcinol derivative and application of the sulfanilamide thiazolyl resorcinol derivative in preparation of a tyrosinase inhibitor and whitening cosmetics. The structural formula of the derivative is # imgabs0 #, in the formula, R represents a fat (aromatic) group substituent, and R'represents a hydrogen atom or methyl; the preparation method comprises the following steps: taking 2-chloro-1-(2, 4-dimethoxyphenyl) ethanone as an initial raw material, carrying out cyclization condensation on the 2-chloro-1-(2, 4-dimethoxyphenyl) ethanone and thiourea to obtain 4-(2-amino-1, 3-thiazole-4-yl) benzene-1, 3-dimethanol, carrying out reaction on 2-amino of thiazole and different fat (aromatic) sulfonyl chloride, and then removing methyl to prepare the 4-(2-amino-1, 3-thiazole-4-yl) benzene-1, 3-dimethanol. Pharmacological activity tests show that the compound has good inhibitory activity on tyrosinase, which indicates that the sulfanilamide thiazolyl resorcinol derivative can be researched and utilized as a novel tyrosinase inhibitor and whitening cosmetics.

The invention relates to the field of automobile foot mats, and discloses a TPE composite material for an automobile foot mat and a preparation method thereof.The composite material comprises a bottom-layer plastic uptake material and a preset three-dimensional material fused on the surface of the bottom-layer plastic uptake material, and the preset three-dimensional material comprises SEBS, low-density polyethylene, EVA, modified nano titanium dioxide, color master batches and auxiliaries; the modified nano titanium dioxide is prepared by grafting a modified additive and nano titanium dioxide, wherein the modified additive is prepared by reacting a functional additive, 2-(2, 4-dihydroxyphenyl)-2H-benzotriazole and a modified antibacterial monomer; the functional additive is prepared by reacting a component I obtained by reducing 2-cyano-6-hydroxybenzothiazole with 5-methylisoxazole-3-formyl chloride; the component I is prepared by reducing 2-cyano-6-hydroxybenzothiazole with 5-methylisoxazole-3-formyl chloride; the modified antibacterial monomer is prepared by reacting benzothiazole-2-formaldehyde with 2, 6-dichloro-4-aminophenol and then reacting with 3-chloropropyltriethoxysilane, and the TPE composite material prepared by the invention can realize a multi-color or multi-pattern effect, and in addition, the material can be endowed with excellent ultraviolet aging resistance, heat resistance and antibacterial property.

The invention belongs to the technical field of fine chemical engineering, and particularly discloses a method for preparing a broad-spectrum bactericide 2-n-butylbenzo [d] isothiazole-3 (2H)-ketone by a molecular editing method. The preparation method comprises the following specific steps: taking 3H-1, 2-benzodisulfophenol-3-ketone and n-butylamine as raw materials, taking Selectfluor as an additive, adding the raw materials and the additive into a mixed solvent, and carrying out heating and stirring reaction, so as to obtain the target product 2-n-butylbenzo [d] isothiazole-3 (2H)-ketone (BBIT). The method is simple and convenient to operate, the raw materials are easy to obtain, the yield is high, thiophenol raw materials or excessive alkali are prevented from being used, and potential application value is achieved.