1161 results about "Substitution reaction" patented technology

The invention discloses a p-methyl benzyl chloride production process and a production system thereof, p-xylene side chains and chlorine are subjected to a gas phase substitution reaction under micro negative pressure and visible light catalysis to generate crude methyl benzyl chloride and hydrogen chloride, and 99.0% methyl benzyl chloride, a small amount of benzyl dichloride and 31% hydrochloric acid are respectively generated through rectification and absorption; the device consists of four working sections of chlorination, rectification, hydrochloric acid absorption and distillation. According to the method, the defects in the prior art are overcome, on one hand, chlorine is introduced, and an aromatic ring chlorination reaction is carried out under visible light catalysis; on one hand, a supported catalyst filler is arranged at the bottom of a chlorination tower, and a zeolite molecular sieve modified by long-chain alkylsilane and supported by metal salt is used as a catalyst to catalyze chloromethylation reaction, on the other hand, the hydrophobicity of the modified catalyst is obviously enhanced, and meanwhile, the density of acidic sites is not reduced; the contact opportunity of the catalyst and a reaction substrate is greatly increased, and the catalytic efficiency of the catalyst is improved.

The invention belongs to the field of pesticides, and relates to a 2-cyano-3-disubstituted phenyl acrylate compound as well as a preparation method and application thereof in pesticides. Carrying out alcoholysis reaction on the benzonitrile compound a and a hydrogen chloride absolute ethyl alcohol solution to obtain an intermediate b; carrying out condensation reaction on the intermediate b and ethyl cyanoacetate under the action of alkali to obtain an intermediate c; the intermediate c and a substituted compound are subjected to a substitution reaction under the action of alkali and a catalyst, and the 2-cyano-3-disubstituted phenyl acrylate compound I is obtained. The 2-cyano-3-disubstituted phenylacrylate compound provided by the invention has good bactericidal activity, and has relatively high bactericidal activity on pathogenic bacteria of chlorosclerotium, fusarium, acrocyst, colletotrichum, cercospora, verticillium and black beancurd skin; the compound can be used for preparing bactericides in the fields of agriculture, horticulture, industry and the like, and has the advantages of broad spectrum, high efficiency, low toxicity and environmental friendliness.

The invention relates to Omarlliptin, in particular to a novel method for preparing Istradafylline, and relates to a preparation method of Istradafylline, in particular to a preparation method of Istradafylline. The method comprises the following steps: carrying out coupling reaction on a compound Ia and TMS acetylene to obtain an intermediate Ib; carrying out bromination reaction on the intermediate Ic under the action of NBS (N-bromosuccinimide) to obtain an intermediate Id; carrying out substitution reaction on the intermediate Id and tert-butyl carbamate under the action of potassium tert-butoxide to obtain an intermediate Ie; reacting the intermediate Ie with paraformaldehyde to obtain an intermediate If; carrying out cycloaddition reaction on the intermediate If and the intermediate Ib to obtain a key intermediate Ig; carrying out asymmetric catalytic hydrogenation reduction on the intermediate Ig to obtain an intermediate Ih; and removing a protecting group from the intermediate Ih in a hydrochloric acid and ethyl acetate system to obtain a final product. The method is short in route, simple and convenient to operate, mild in condition, high in reaction yield, environment-friendly and easy for industrial production, and dangerous and highly toxic products are prevented from being used and hazardous chemicals are supervised. # imgabs0 #

The invention belongs to the technical field of flame-retardant materials, and particularly relates to preparation of a phosphorus, nitrogen and silicon macromolecular flame retardant and application of the phosphorus, nitrogen and silicon macromolecular flame retardant in epoxy resin. The preparation method comprises the following steps: firstly, carrying out substitution reaction on chlorosilane and syringaldehyde or vanillic aldehyde to synthesize a silicon-containing intermediate, then carrying out Schiff base reaction on the silicon-containing intermediate and an amine compound, and finally carrying out addition reaction on the silicon-containing intermediate and a phosphorus-containing compound to prepare the phosphorus, nitrogen and silicon macromolecular flame retardant. The flame retardant has a good flame-retardant effect, can be used for preparing flame-retardant epoxy resin, can effectively improve the limit oxygen index and the vertical combustion grade of the epoxy resin, and can endow the epoxy resin with good transparency and molten drop resistance.

The invention belongs to the field of photovoltaic materials, and provides a preparation method and application of a self-assembly hole transport material.The preparation method synthesizes a class of new carbazole derivatives through a new process synthesis route, five classes of self-assembly hole transport materials can be synthesized and prepared through four steps, the legal method is simple, the cost is low, and the method is suitable for large-scale production. And expensive raw materials can be avoided, the yield is high, and the method is suitable for large-scale preparation. In the third step of the preparation method, a bromocarbazole substituent coupling substitution reaction is taken as a purpose, so that the process of connecting the hydrophilic group containing the aromatic ring is realized, and equivalently, a method for introducing the hydrophilic functional group containing the aromatic ring to the upper end of carbazole is included and provided. The self-assembled hole transport material obtained by the preparation method can achieve the effects of improving hydrophilicity and optimizing a passivated perovskite lower interface, so that the conversion efficiency and the stability of a perovskite battery can be further improved.

The invention discloses a preparation method of a dual PDE3 / 4 inhibitor Encephaline. The preparation method comprises the following steps: carrying out a sizuki coupling reaction on initial raw materials of a compound shown as a formula 1 and a compound shown as a formula 2 to obtain a compound shown as a formula 3, carrying out intramolecular cyclization to obtain a compound shown as a formula 4, converting carbonyl into a compound shown as a formula 5 by using POCl3, and carrying out an alkylation reaction on the compound shown as a formula 5 and a compound shown as a formula 6 to obtain a compound shown as a formula 7. Wherein the acyl imine of the compound as shown in the formula 7 and a compound as shown in a formula 8 are subjected to substitution reaction to obtain the product Encephaline. The selected raw materials are easy to obtain, the operation method is simple and convenient, the product yield is high, and the method is suitable for batch production.

The invention discloses a thiazolinone acrylic acid silane ester self-polishing antifouling resin and a preparation method and application of the thiazolinone acrylic acid silane ester self-polishing antifouling resin. The preparation method of the thiazolinone acrylic acid silane ester self-polishing antifouling resin mainly comprises the following steps: in a nitrogen environment, adding an initiator, the preparation method comprises the following steps: carrying out random free radical polymerization reaction on thiazolinone methacrylate, methyl methacrylate, ethyl acrylate, triisopropyl silicon-based methacrylate and phenyl dimethyl silicon-based methacrylate by taking azodiisobutyronitrile and benzoyl peroxide as initiators to synthesize the photoinitiator. Wherein the thiazolinone methacrylate monomer is prepared by grafting double bonds on 5-chloro-2-benzothiazolinone and methacryloyl chloride through a substitution reaction, then grafting hydroxyl on the 5-chloro-2-benzothiazolinone and mercaptoethanol through a mercapto-alkene click reaction and finally carrying out a substitution reaction on the 5-chloro-2-benzothiazolinone and methacryloyl chloride. According to the invention, the coating still has good surface self-renewal capability even in a static environment so as to inhibit the adhesion of large fouling organisms.

The invention discloses a synthesis method of a non-silicon defoaming agent and application of the non-silicon defoaming agent in the field of scandium extraction in hydrometallurgy. The defoaming agent is synthesized by a component A, a component B and a component C through a two-step reaction, the synthesis method comprises the following specific synthesis steps: 1) carrying out esterification reaction on an amino acid substance A and a fatty alcohol substance B to generate an amino ester substance D; and 2) carrying out substitution reaction on the amino ester substance D and a triazine compound C to obtain the non-silicon defoaming agent. The defoaming agent disclosed by the invention is wide in application range, can be applied to links such as a laterite-nickel ore hydrometallurgy front-end scandium extraction method and an MHP hydrometallurgy scandium impurity removal process, is added as an auxiliary agent in the extraction process, and is used for reducing the surface tension of liquid, preventing the formation and enrichment of a third-phase substance and reducing the occurrence of an emulsification phenomenon; the process stability and the output quality are improved, and the method has important industrial application value.

The invention discloses a preparation method of an FSP1 inhibitor FSEN3, which comprises the following steps: by taking 4-methoxybenzoyl hydrazine and allyl isothiocyanate as raw materials, forming a thiourea intermediate through nucleophilic addition reaction, carrying out cyclization reaction under the action of alkali, then reacting with liquid bromine to construct a thiazolotriazole skeleton, and finally preparing the FSP1 inhibitor FSEN3. And then carrying out substitution reaction with indoline to obtain a target product FSEN3 as shown in a formula (I). The total synthesis method provided by the invention is mild in condition, simple and convenient to operate and high in total yield. # imgabs0 #

The invention belongs to the technical field of organic compounds, and particularly relates to a multifunctional organic silicon glycosyl amide cationic surfactant as well as a preparation method and application thereof. The preparation method of the surfactant comprises the following steps: carrying out amine ester reaction on glucolactone and N, N-dimethyl dipropylene triamine to obtain a precursor; carrying out substitution reaction on the precursor and bromododecane to obtain an intermediate; the intermediate and 3-chloropropyl methyl dimethoxy silane or 3-chloropropyl methyl trimethoxy silane are subjected to a quaternization reaction, and the surfactant is obtained. The surfactant has good environmental protection property and biocompatibility, is non-toxic and non-irritant, can sterilize and improve the rewettability of the material surface, and has wide application prospects in the aspects of pesticide, textile, daily chemical industry and material transportation and storage.

The invention discloses a compound containing a urea structure as well as a preparation method and application of the compound in a color developing agent, and relates to the technical field of color developing agents. The compound containing the urea structure is a # imgabs0 # structure as shown in a formula 1. The compound containing the urea structure is synthesized through multiple steps of Suzuki reaction, bromination reaction and substitution reaction. The compound is used as an electron donor to be applied to a thermosensitive color development system and forms a color development composition with a phenolic compound and an acidic material, and the activation temperature is as low as 60-120 DEG C. The ureido structure stabilizes a reaction intermediate through a hydrogen bond network, enhances the electron transfer efficiency, and significantly improves the color developing sensitivity; the aryl / heteroaryl substituent optimizes the color contrast through the conjugation effect, and meanwhile, the synergistic effect of the hot-melt filler ensures the stability of the system. Compared with a traditional color developing agent, the color developing agent has the advantages of low-temperature activation, high color developing intensity and excellent weather resistance, is suitable for the fields of thermal printing, anti-counterfeiting materials and the like, and overcomes the defects of high reaction temperature and insufficient stability in the prior art.

The invention discloses a preparation method of a multifunctional group synergistic modified aluminum silicate nanofiber membrane, which comprises the following steps: modifying aluminum silicate nanofiber by using an amino silane coupling agent to obtain aminated aluminum silicate nanofiber; grafting a polyamino compound to the surface of the aminated aluminum silicate nanofiber by utilizing the cross-linking effect of 1, 3-dichloropropanol through a substitution reaction of amino and chlorine, so as to obtain a multifunctional aluminum silicate nanofiber; 2-butenal is modified on the surface of the multi-functionalized aluminum silicate nanofiber by utilizing an ammonia-aldehyde condensation reaction, so that the multi-functionalized aluminum silicate nanofiber rich in double bonds is obtained; carrying out cross-linking polymerization by taking itaconic acid as a monomer and the multi-functional aluminum silicate nanofiber rich in double bonds as a cross-linking agent, then carrying out suction filtration to form a membrane, and drying to obtain the multi-functional synergistic modified aluminum silicate nanofiber membrane with the gram weight not exceeding 15g / m < 2 >. According to the invention, high-efficiency adsorption of heavy metals is realized, and the problem that aluminum silicate nanofibers are not easy to recover is solved.

The invention provides a method for preparing squaric acid and a method for preparing a lithium supplement agent of lithium squarate. The method for preparing squaric acid comprises the steps of preparing an intermediate I, preparing an intermediate II and preparing squaric acid. The method for preparing the squaric acid is a novel squaric acid synthesis route, and the squaric acid is obtained through cycloaddition / substitution reaction of perchloroprene serving as an initial raw material and morpholine, hydrolysis / rearrangement reaction in a buffer system and acid hydrolysis reaction in sequence. The method for preparing squaric acid has the advantages of simple reaction steps, mild reaction conditions, high yield, low cost and the like. The invention also provides a method for preparing the lithium squarate lithium supplement agent, and the prepared squaric acid and lithium-containing alkali are blended in a solvent for reaction to generate the lithium squarate. The method for preparing the lithium squarate lithium supplement has the advantages of simple reaction steps, mild reaction conditions, high yield, low cost and the like.

The invention relates to a preparation method of 2-(2-amino-5-bromo-benzoyl) pyridine, which comprises the following steps: by taking 1, 2-diphenyl-1H-benzimidazole (I) as a starting material, oxidizing under the action of chromium trioxide and acetic acid to obtain N-[2-(2-pyridinecarbonyl) phenyl] benzamide (II), hydrolyzing the N-[2-(2-pyridinecarbonyl) phenyl] benzamide (II) under the action of sulfuric acid to obtain 2-(2-aminobenzoyl) pyridine (III), and reacting the 2-(2-amino-5-bromo-benzoyl) pyridine (III) with the 2-(2-amino-5-bromo-benzoyl) pyridine (III) to obtain the 2-(2-amino-5-bromo-benzoyl) pyridine. And (III) performing substitution reaction with NBS in DCM to obtain the target product 2-(2-amino-5-bromo-benzoyl) pyridine. The method has the advantages of mild reaction conditions, higher product purity, high yield, simplicity and convenience in operation, low cost and easiness in industrialization.

The invention relates to a self-crosslinking flame-retardant insulating material and a preparation method thereof, and belongs to the technical field of insulating material preparation. The self-crosslinking flame-retardant insulating material comprises the following raw materials: polyethylene, modified vinyl silane, an epoxy flame retardant, a water producing agent, a catalyst and an initiator, the modified vinyl silane is prepared from a ring-opening reaction product and a diamine compound through a condensation reaction; the ring-opening reaction product is prepared from an epoxy silane coupling agent and a 2, 2-dimethylolpropionic acid derivative through a reaction; the 2, 2-dimethylolpropionic acid derivative is prepared from 2, 2-dimethylolpropionic acid and acrylic acid through esterification reaction; the epoxy flame retardant is prepared from a hydroxyl-terminated dendritic compound and an epoxidation agent through an epoxidation reaction; the hydroxyl-terminated dendritic compound is prepared from hexachlorocyclotriphosphazene and alkyl binary primary alcohol through a substitution reaction. By introducing the modified vinyl silane and the epoxy flame retardant, a bi-crosslinking interpenetrating network is formed in the obtained material, so that the problems in the background technology are solved.

The invention relates to the technical field of polyurethane coatings, and discloses a preparation method of an antibacterial wear-resistant waterborne polyurethane coating, which comprises the following steps: taking concentrated hydrochloric acid, p-phenylenediamine, sodium nitrite, paraformaldehyde, amino-modified nano silicon dioxide and hexamethylene diisocyanate as raw materials; the preparation method comprises the following steps: taking 9, 10-dihydro-9-oxa-10-phosphaphenanthrene-10-oxide as a raw material, carrying out diazotization coupling reaction, substitution reaction, Mannich reaction and addition reaction to prepare modified polyisocyanate, then taking 9, 10-dihydro-9-oxa-10-phosphaphenanthrene-10-oxide and ((2-aminoethyl) azadiyl) dimethanol as raw materials, carrying out substitution reaction to prepare DOPO-based dihydric alcohol, and carrying out reaction to prepare the DOPO-based dihydric alcohol. Finally, the modified polyisocyanate, DOPO-based dihydric alcohol and polyethylene glycol 400 are used as raw materials, an antibacterial wear-resistant polyurethane emulsion is prepared through a prepolymerization reaction and a chain extension reaction, and the prepared polyurethane coating has good antibacterial, anti-ultraviolet, flame-retardant and wear-resistant properties.

The invention discloses a preparation method of a phenolic chitosan quaternary ammonium salt antibacterial agent, which comprises the following steps: alkalizing chitosan at low temperature, then carrying out substitution reaction on the alkalized chitosan and a carboxylic acid derivative, and introducing a reactive carboxyl group on the hydroxyl of the chitosan to obtain O-carboxylated chitosan, so as to provide reactive sites for subsequent secondary modification; the preparation method comprises the following steps: preparing O-carboxylated chitosan, introducing a quaternary ammonium salt group on an amino group of the O-carboxylated chitosan through a ring-opening reaction so as to improve the antibacterial property and water solubility of the chitosan, and finally reacting with a phenolic derivative to obtain the phenolic chitosan quaternary ammonium salt antibacterial agent. According to the preparation method of the phenolic chitosan quaternary ammonium salt antibacterial agent, industrial production is easy, and the prepared phenolic chitosan quaternary ammonium salt antibacterial agent has good antibacterial performance and free radical scavenging capacity and also has good water solubility.

The invention relates to the technical field of synthesis of photosensitive organic compounds, and discloses a novel hydroxyl-containing dihydropyridine photosensitizer and a preparation method and application thereof.The method comprises the steps that 5-hydroxy-2-nitrobenzaldehyde serves as an initial raw material and reacts with 3-aminocrotonic acid methyl benzoate under the catalytic action of trifluoroformic acid, and a reaction product is obtained; precipitating, filtering and recrystallizing the product to obtain a photosensitive dihydropyridine monomer; the preparation method comprises the following steps: by taking 3, 5-dibromophenol as an initial raw material, introducing halogenated straight-chain alkyl of which the tail end is halogen into a hydroxyl position on the 3, 5-dibromophenol; dissolving a photosensitive dihydropyridine monomer and the intermediate A, and carrying out substitution reaction under the action of alkali to prepare an intermediate B; and carrying out Suzuki coupling reaction on the intermediate B and 4-hydroxymethyl phenylboronic acid to finally obtain the novel dihydropyridine photosensitizer containing hydroxyl. The novel hydroxyl-containing dihydropyridine photosensitizer (DHPDO) is good in compound stability, the preparation process is simple and convenient, the stability of an intermediate product is high, and after-treatment purification is low in toxicity and harmless.

The present invention discloses a pimobendan intermediate synthesis method, which comprises: 1, carrying out a Friedel-Crafts acylation reaction on a compound I and a compound A in an aprotic solvent under the effect of a Lewis acid to generate a compound II; 2, ether is used as a solvent, under the alkaline condition, the compound II and dimethyl malonate or diethyl malonate are subjected to a substitution reaction, the generated compound is subjected to a hydrolysis reaction in an aqueous alkali solution, and a compound III is generated; and 3, heating the compound III under the conditions of hydrazine hydrate and acid to generate a compound IV, namely the pimobendan intermediate. The synthesis method cancels a nitration reaction step which is high in risk and generates a large amount of waste acid water, and is short in route step and simple to operate.

The invention discloses a preparation method of tert-amyl peroxypivalate and an initiator, and belongs to the technical field of preparation of initiators. The preparation method comprises the following steps: by taking water as a solvent, when tert-amyl hydrogen peroxide and caustic soda liquid react to generate tert-amyl peroxide salt, the tert-amyl peroxide salt and pivaloyl chloride are subjected to substitution reaction to obtain the tert-amyl peroxide, and the substitution reaction speed of the pivaloyl chloride is higher than the hydrolysis speed of the pivaloyl chloride. Auxiliary materials are dispersed in an oil phase, shearing and emulsifying are carried out, the peroxide pivalate initiator is obtained, the auxiliary materials comprise an emulsifying agent, a dispersing agent, an anti-freezing agent and water, and the oil phase adopts the peroxide pivalate obtained through the method. The oil-phase raw material residue is low, and the storage stability time of the initiator emulsion prepared from the oil phase is longer than 30 months.

The problem of the present invention is to provide a plating stack (a stack of plating films) for applying on surface of conductor circuits or the like, the plating stack can maintain high bond strength when solder is bonded on that and can be produced stably. In the method for producing a plating stack of the present invention, a plating layer A mainly composed of a second metal is deposited on an object to be plated S mainly composed of a first metal by a substitution reaction, then a plating layer B mainly composed of palladium is deposited on the plating layer A, and then a plating layer C mainly composed of nickel is deposited on the plating layer B by a redox reaction. The first metal is, for example, copper. The second metal is, for example, gold, platinum or silver.

The invention belongs to the technical field of electrochromic materials, and provides a red-transparent display electrochromic polymer and a preparation method thereof. The method disclosed by the invention comprises the following steps: carrying out ring formation reaction on N-(2, 5-dibromophenyl)-2-ethylhexyl thioamide, potassium ferricyanide and sodium hydroxide to obtain 4, 7-dibromo-2-(heptane-3-yl) benzothiazole; the preparation method comprises the following steps: carrying out substitution reaction on EDOT, n-butyllithium and tributyltin chloride to obtain EDOT-Sn; the preparation method comprises the following steps: carrying out Stille coupling reaction on 2, 4, 7-dibromo-2-(heptane-3-yl) benzothiazole and EDOT-Sn, and then carrying out electrochemical polymerization reaction to obtain the electrochromic polymer. A pure donor (D) type organic molecule is obtained by the method, a corresponding electrochromic film is prepared by electrochemical polymerization, reversible switching between red and transparency is realized, and the electrochromic film has good cycle stability and high color change response speed.

The invention provides a preparation method of a bexagliflozin intermediate, and relates to the technical field of organic synthesis. The preparation method provided by the invention comprises the following steps: S1, substitution reaction: under the action of alkali, carrying out substitution reaction on 2-(cyclopropoxy) ethanol and a compound III ((5-halogen-2-chlorphenyl) (4-halophenyl) ketone) to generate a compound II; s2, reduction reaction: under the action of lewis acid, carrying out reduction reaction on a reducing agent and a compound II ((5-halogen-2-chlorphenyl) (4-(2-(cyclopropoxy) ethyoxyl) phenyl) ketone) to generate a compound I; the method has the advantages of mild reaction conditions, high atom utilization rate, high yield, high product quality and the like.

The invention discloses a preparation method of 1-cyclopropylpiperazine, which belongs to the technical field of pharmaceutical chemicals, and comprises the following steps: taking diethanol amine as a starting material, and carrying out substitution reaction with a sulfonyl reagent to generate an intermediate I; reacting the intermediate I with cyclopropylamine to generate an intermediate II; the intermediate II is subjected to a sulfonyl removal reaction, and 1-cyclopropyl piperazine is generated; compared with the prior art, the synthesis route provided by the invention has the advantages that the initial raw materials are simple and easy to obtain, and the 1-cyclopropylpiperazine is simply, conveniently and efficiently obtained by adopting the inorganic base as the acid-binding agent in the reaction; the problems of high danger and toxicity, high production cost and low production efficiency in the existing preparation process of the 1-cyclopropylpiperazine are solved.

The invention discloses a polyurethane coating and a preparation method thereof, and belongs to the technical field of antibacterial coatings. The preparation method of the polyurethane coating comprises the following steps: carrying out acyl chloride substitution reaction on a phenolic substance and a chlorine donor to obtain an intermediate reactant, and carrying out conjugate addition reaction on the intermediate reactant and an amine substance with hydroxyl groups at two ends to obtain antibacterial diol; reacting the antibacterial diol with isocyanate to obtain a polyurethane coating; the phenolic substance is selected from at least one of thymol, carvacrol, paeonol, catechol and theaflavin. The antibacterial coating is applied to the aspect of an antibacterial coating of a food contact part, the problem that the antibacterial property of an existing antibacterial coating is difficult to last is solved, and the antibacterial coating has the synergistic antibacterial effect of killing and defending bacteria.

The invention relates to a gemini surfactant for thickened oil recovery and a preparation method thereof, and belongs to the technical field of thickened oil recovery. The preparation method of the gemini surfactant for thickened oil recovery comprises the following steps: dissolving ethylene glycol dihydric alcohol and paratoluensulfonyl chloride in a tetrahydrofuran solvent, and carrying out substitution reaction under an alkaline condition to obtain an intermediate I; adding nonyl phenol and the intermediate I into a mixed solvent of tetrahydrofuran and N, N-dimethylformamide, and carrying out etherification reaction under an alkaline condition to obtain a gemini precursor II; and mixing an alkylphenol polyoxyethylene ether surfactant, the gemini precursor II and a formaldehyde aqueous solution, and carrying out a phenolic aldehyde condensation polymerization reaction under an acidic condition to obtain the gemini surfactant. The gemini surfactant prepared by the preparation method has good temperature resistance and salt tolerance, the preparation method is simple, the synthesis cost is low, and the gemini surfactant has good economical efficiency and is beneficial to realizing large-scale industrial production.

The invention discloses a cationic self-assembly high-temperature-resistant clay stabilizer and a preparation method thereof.The preparation method sequentially comprises the following steps that firstly, N-methylbenzylamine, diethylenetriamine and epichlorohydrin are subjected to a substitution reaction, and polyquaternary ammonium containing quaternary ammonium ions and benzyl is prepared; then carrying out a reaction on the mono6-amino-beta-cyclodextrin and epoxy chloropropane, so as to prepare a beta-cyclodextrin-epoxy chloropropane condensation compound; and finally, blending and assembling the two substances to generate the cation assembled compound with relatively high cation degree and high temperature resistance. Polyquaternary ammonium containing quaternary ammonium ions and benzyl in the cation assembly compound provides quaternary ammonium cations combined with anionic charges on the surface of stratum clay minerals on one hand, and provides benzene rings combined with beta-CD holes of the beta-cyclodextrin-epichlorohydrin condensation compound on the other hand. The prepared clay stabilizer has good high temperature resistance, has a good clay anti-swelling effect under a strong alkaline condition, and can improve the crude oil recovery rate.

The invention provides a preparation method and application of an asymmetric dicyclopentadienyl dialkoxy zirconium compound, and the preparation method comprises the following steps: (1) mixing a solvent with ZrCl4 and sodium cyclopentadienyl CpNa, and carrying out a reaction to obtain CpZrCl3; (2) the CpZrCl3 obtained in the step (1) and R1 substituted sodium cyclopentadienyl R1CpNa are subjected to a mixed reaction, and (R1Cp) CpZrCl2 is obtained; and (3) mixing the (R1Cp) CpZrCl2 obtained in the step (2) with alkoxy sodium salt R2Na, and carrying out a reaction so as to obtain the asymmetric dicyclopentadiene dialkoxy zirconium compound. According to the method, the substitution reaction of three sodium salts is used for replacing the ligand replacement reaction in the prior art, so that the reaction steps are shortened, the use of unnecessary raw materials is avoided, the production cost is reduced, and the obtained target product is high in yield and high in purity.

The invention belongs to the technical field of chemical synthesis, and particularly relates to a preparation method of perfluorohexyl octane. The preparation method comprises the following steps: by taking perfluorohexyl ethyl iodide as a raw material, firstly carrying out Grignard reagent exchange with a reagent A, and then carrying out nucleophilic addition reaction with n-hexanal to obtain a compound III; carrying out esterification and substitution on the compound III to prepare a compound V, or carrying out an Apple substitution reaction to prepare the compound V; and carrying out reduction reaction on the compound V, rectifying and purifying to obtain a target product. The reagent A comprises an isopropyl magnesium chloride tetrahydrofuran solution, a methyl magnesium chloride tetrahydrofuran solution, a methyl magnesium bromide tetrahydrofuran solution, an ethyl magnesium chloride tetrahydrofuran solution, an ethyl magnesium bromide tetrahydrofuran solution and / or a phenyl magnesium bromide tetrahydrofuran solution. According to the method, the perfluorohexyl ethyl iodide and the n-hexanal are used as raw materials to prepare the perfluorohexyl octane, isomer impurities are fundamentally avoided, and the method has the advantages that purification is easy, the yield is high, the product purity is high, and industrial production is facilitated.

The invention discloses a novel BOPP (biaxially-oriented polypropylene) pearlized film loaded with a composite antibacterial material as well as a preparation method and application of the novel BOPP pearlized film, and the specific scheme is as follows: a KH550 coupling agent is hydrolyzed, a hydrolysate is modified on nano titanium dioxide (TiO2) particles, a natural antibacterial material eugenol (Eug) is brominated by a substitution reaction, and an Eug-TiO2 composite antibacterial material is further prepared based on nucleophilic substitution. And finally, carrying out melting plasticizing, extrusion casting and two-way stretching on polypropylene and pearlescent master batch to prepare the novel BOPP antibacterial pearlescent film, so that the strong activity, high stability, long action time, safety and environmental protection of the antibacterial process of the BOPP pearlescent film are realized, the added value attribute of the BOPP product is improved, and the application scene of the BOPP pearlescent film is expanded.