50 results about "Benzenesulfonates" patented technology

The present invention addresses the problem of providing a high-quality solid preparation containing milobalin benzene sulfonate and having excellent storage stability. The solution of the present invention is a solid preparation for medical use, which contains milobalin benzene sulfonate and does not substantially contain a reducing sugar.

The invention discloses a hydrogenation device scale inhibitor for heavy high-sulfur raw oil and a preparation method of the hydrogenation device scale inhibitor, and relates to the technical field of scale inhibitors. The scale inhibitor is prepared from a polyisobutylene succinimide dispersing agent, a high-temperature-resistant scale inhibition dispersing agent, an anti-rust agent, an imidazoline corrosion inhibitor, an antioxidant, a sulfide chelating agent, a clearing agent, cup carbazole alkylbenzene sulfonate and a solvent in specific parts by weight. The preparation method comprises the following steps: heating the solvent to 80-100 DEG C, sequentially adding the other components, and stirring for 30-40 minutes. Aiming at the characteristics of heavy high-sulfur raw oil, the scale inhibitor realizes high scale inhibition rate, excellent high-temperature stability and strong sulfur corrosion resistance through a multi-component synergistic effect, effectively solves the problems of scaling and corrosion of a hydrogenation device, prolongs the operation cycle of the device, and is suitable for a hydrogenation process of high-sulfur and high-asphaltene raw oil.

To provide crystalline forms of a C-C chemokine receptor type 4 antagonist.SOLUTION: There is provided the compound 2 - ((R) - 3 - (1 - (1 - ((R) - 1 - (2, 4-dichlorophenyl) ethyl) - 3 - (trifluoromethyl) - 1H - pyrazolor3, 4-b] pyrazin-6-yl) azetidin-3-yl) piperidin-1-yl) ethan-1-ol benzenesulfonate in crystalline form.SELECTED DRAWING: Figure 1

The invention discloses a heavy non-aqueous phase liquid pollution remediation precursor solution, a preparation method and a remediation method. The heavy non-aqueous phase liquid pollution remediation precursor solution comprises 5-10 parts by volume of a surfactant, 1-5 parts by volume of a cosurfactant and 80-90 parts by volume of water; the surfactant is prepared from the following components in parts by volume: 10 to 20 parts of an oleophylic nonionic surfactant, 10 to 20 parts of an oleophylic hydrophilic nonionic surfactant and 50 to 75 parts of a gemini type surfactant; the cosurfactant is one or a combination of two of alkenylene benzene sulfonate and thiourea. According to the precursor solution, a surfactant and a cosurfactant are mixed to form a microemulsion precursor solution, the microemulsion precursor solution is injected into an underground environment, and residual phase DNAPLs in an aquifer is used as an oil phase to form an in-situ microemulsion, so that the purpose of efficiently removing the DNAPLs is achieved.

The present invention relates to a method for efficiently producing a compound derived from the commercially available and readily available 3-((3S)-7-bromo-2-((2-hydroxypropyl)amino)-5-(pyridin-2-yl)-3H-benzo[e][1,4]diazepine-3-yl)propionate methyl ester, namely, the compound 3-[(4S)-8-bromo-1-methyl-6-(2-pyridinyl)-4H-imidazo[1,2-a][1,4]benzodiazepine-4-yl]propionate methyl ester benzenesulfonate (remimazolam besylate).

The present invention relates to a process for the preparation of N-(5-chloropyridin-2- yl)-N'-[(1S,2R,4S)-4(N,N-dimethylcarbamoyl)-2-(5-methyl-4,5,6,7-tetrahydro [1,3] thiazolo[5,4-c] pyridine-2-carboxamido)cyclohexyl]oxamide, 4- methylbenzenesulfonate. It further relates to a process for the purification of N-(5- chloropyridin-2-yl)-N'-[(1S,2R,4S)-4(N,N-dimethylcarbamoyl)-2-(5-methyl-4,5,6,7- tetrahydro [1,3] thiazolo[5,4-c] pyridine-2-carboxamido)cyclohexyl]oxamide, 4- methylbenzenesulfonate is having purity greater than 99% by HPLC, preferably greater than 99.5% and more preferably 99.9% by HPLC.

The invention relates to a bimodal trigger intelligent diaphragm, a battery, a preparation method and application. The bimodal trigger intelligent diaphragm comprises a base film, and a thermal response layer and an electric response layer which are respectively positioned on two sides of the base film, the thermal response layer is prepared from the following raw materials in percentage by weight: 30 to 50 percent of capsule, 10 to 15 percent of PVDF-HFP and the balance of solvent; the capsule comprises a Wood alloy and a capsule wall wrapping the Wood alloy, the material of the capsule wall is polymethyl methacrylate, and the composition of the Wood alloy is Bi < 50 > Pb < 2. 7 > Sn < 1. 3 > Se < 0.5 > Cd10. The electric response layer is prepared from the following raw material components: 0.2 to 0.5 M of N-(4-sulfonyl butyryl) aniline, 0.6 to 1.5 M of sulfuric acid and 0.05 to 0.2 M of benzene sulfonate; according to the invention, dual protection is realized through thermal response and electrical response, the sensitivity, stability and response speed of thermal protection are effectively improved, and the protection effect is improved.

The invention relates to a benzene sulfonate compound for forming an organic film, a composition for forming an organic film, a method for forming an organic film, and a method for forming a pattern. The present invention addresses the problem of providing: a film which has excellent coating properties such as coating defects, film-forming properties, and embedding properties when an organic underlayer film for a multilayer resist is used; the present invention relates to a composition for forming an organic film, which uses a benzene sulfonate that does not belong to a perfluoroalkyl compound (PFAS) and is useful as a photoresist material, a pattern forming method using the same, and a compound suitable for the same. [Solution] A composition for forming an organic film, which is characterized by containing (A) a resin and / or a compound for forming an organic film, (B) a benzene sulfonate compound that is represented by formula (1) and that does not contain a perfluoroalkyl group, the molecular weight of the anionic moiety in the formula (1) being 200 or more, and (C) a solvent. In the formula, R1, n and A + are as defined herein.

Disclosed are a type-1 crystal, a type-3 crystal, and a type-4 crystal of N-(3-chloro-2-methylphenyl)-2-(methoxymethyl)-6-({[2-(trifluoromethyl)phenyl]carbonyl}amino)-1H-benzimidazole-4-carboxamide 4-methylbenzene sulfonate represented by formula (A-I).

Provided herein are methods for treatment of chorea associated with Huntington disease using a vesicular monoamine transporter isoform 2 (VMAT2) inhibitor. In certain embodiments, the VMAT2 inhibitor is valbenazine or a pharmaceutically acceptable salt thereof.

The invention relates to a benzofuranone compound salt form and / or crystal form with a structure shown in a formula I as well as a preparation method and application of the benzofuranone compound salt form and / or crystal form. The invention provides a pharmaceutically acceptable salt of a benzofuranone compound as shown in a formula I. The pharmaceutically acceptable salt is one of hydrochloride, sulfate, phosphate, hydrobromide, maleate, tartrate, fumarate, citrate, p-toluenesulfonate, benzene sulfonate, mesylate, succinate, acetate and lactate. The salt formed by the compound shown in the formula I has a structure shown in a formula II, and n is selected from 1 or 2. The dynamic solubility is better, the stability is better, the absorption of the medicine, the stability of the medicine effect and the storage stability are facilitated, and the pharmaceutical prospect is better.

This invention belongs to the field of postharvest preservation technology for agricultural products, specifically relating to a preservation and antiseptic composition containing octenylamine and its application. The preservation and antiseptic composition containing octenylamine has an active ingredient composed of octenylamine and a compounding factor; wherein the compounding factor is selected from at least one of imazalil, thiabendazole, imazalil, biguanide trioctylbenzene sulfonate, and thiamethoxam. The preservation and antiseptic composition of this invention uses octenylamine as its core, and by combining it with other highly effective fungicides, the compounded combination exhibits a significant synergistic effect, possessing high efficiency, low toxicity, low residue, and effectively delaying the development of drug resistance. It can provide support for postharvest preservation and antiseptic treatment of agricultural products, and has significant practical significance and market value.

Forms of the tosylate salt of 6-[(4,4-difluorocyclohexyl)amino]-2-fluoro-3-pyridyl]- [4-(2,2,2-trifluoroethylamino)-7H- pyrrolo[2,3-d]pyrimidin-5-yl]methanone] (Compound I tosylate) were prepared and characterized in the solid state: Also provided are processes of manufacture and methods of using the forms of Compound I tosylate.

The invention discloses a glyphosate and 2, 4-D acid compounded broad-spectrum herbicide and application thereof, and belongs to the technical field of herbicide preparation. The preparation method of the herbicide comprises the following steps: mixing glyphosate, 2, 4-D acid and water, heating, adding ammonia water for neutralization reaction, adding lauramide propyl dimethylamine, an emulsifier, a natural source penetration enhancer, ethoxylated castor oil, a block copolymer, alkylbenzene sulfonate, an antifreezing agent and other assistants, stirring, cooling, and adjusting the pH value to obtain the herbicide. Compared with the prior art, the broad-spectrum herbicide disclosed by the invention has a remarkable control effect on uncultivated land weeds, and solves the technical problem that active ingredients in a traditional formula are difficult to effectively penetrate through a plant wax barrier.

Provided are: a dispersion with which nano-sized molybdenum disulfide particles capable of highly expressing lubricating performance can be stably dispersed even over time; a lubricating composition comprising the same; and a simple method for producing the same. Specifically, provided are: a dispersion comprising molybdenum disulfide particles (A) having a specific surface area of at least 40 m2 / g, and at least one compound (B) selected from the group consisting of secondary nitrogen-containing compounds and organic acid salts; and a lubricating composition obtained by mixing said dispersion with a base oil. The compound is preferably at least one compound (B1) selected from the group consisting of: compounds having a substituted succinimide group and a secondary nitrogen-containing group; alkylbenzene sulfonates; and alkyl salicylates.

This invention discloses a benzenesulfonate containing a piperidine ring compound, its preparation method, and its application. Specifically, this invention provides a compound 2. Compound 2 is stable, and through the salt preparation step, the content of isomer impurities, such as those shown in Formula 1′, can be significantly reduced.

The application relates to a benzofuranone compound salt type and / or crystal type with a structure of formula I and a preparation method and application thereof. The application provides a pharmaceutically acceptable salt of a benzofuranone compound shown in formula I, wherein the pharmaceutically acceptable salt is one of hydrochloride, sulfate, phosphate, hydrobromide, maleate, tartrate, fumarate, citrate, p-toluenesulfonate, benzenesulfonate, methanesulfonate, succinate, acetate and lactate; the salt formed by the compound of formula I has a structure as shown in formula II, and n is selected from 1 or 2. The dynamic solubility is better, the stability is better, the drug absorption is facilitated, the drug efficacy is stable, the storage stability is good, and the application prospect is better.

To provide an organic film forming composition employing a benzenesulfonate that is not classified as a perfluoroalkyl compound (PFAS), the composition enabling formation of a film with excellent coating properties when used as an organic underlayer film for a multilayer resist and being useful as a photoresist material.SOLUTION: An organic film forming composition contains an organic film forming resin and / or compound (A), a benzenesulfonate compound (B) represented by the following formula (1), in which an anion moiety in the formula (1) has a molecular weight of 200 or more and which does not contain a perfluoroalkyl group, and a solvent (C).SELECTED DRAWING: Figure 1

The present invention provides methods of preparing compound of Formula (I), wherein the compounds are represented by the structure of Formula (I) wherein: R1 each is independently F, Cl, Br, I, OCH3, CN or NO2; R2 each is independently identical or different C1-C5 alkyl; n1 is an integer between 1 and 5; and n2 is an integer between 1 and 4. In addition, the present invention provides a compound represented by the following structures: Compound (1a) and Compound (2), wherein X comprises: chloride, acetate, adipate, alginate, ascorbate, aspartate, benzoate, benzenesulfonate, bisulfate, borate, butyrate, citrate, camphorate, camphorsulfonate, cyclopentanepropionate, digluconate, dodecylsulfate, ethanesulfonate, fumarate, glucoheptanoate, glycerophosphate, hemisulfate, heptanoate, hexanoate, hydroiodide, maleate, 2-hydroxyethanesulfonate, lactate, methanesulfonate, 2-naphthalenesulfonate, nicotinate, nitrate, oxalate, pectinate, persulfate, 3-phenylpropionate, phosphate, picrate, pivalate, propionate, salicylate, succinate, sulfate, sulfonate, tartrate, thiocyanate, toluenesulfonate, or undecanoate salt, or any combination thereof.

The invention relates to besylate salts of the compound of formula (I):Methods of preparing the salts, and their use as medicaments, in particular for sedative or hypnotic, anxiolytic, muscle relaxant, or anticonvulsant purposes is also described.

The invention relates to a 2'-(3'-phenylureido)phenyl 3-(3-phenylureido)benzenesulfonate in the polymorphic form β22.2, characterised by an X-ray powder diffractogram having the Bragg angles (2θ / CuKα) 8.4, 11.0, 12.0, 12.7, 14.7, 16.5, 18.2, 19.4, 20.8, 21.1, 22.2, 25.7, 26.6, 26.9, 33.2, or in the polymorphic form α9.2, characterised by an X-ray powder diffractogram having the Bragg angles (2θ / CuKα) 8.3, 9.2, 15.1, 17.6, 20.0, 22.2, 23.1, 23.4.

The present invention relates to novel crystalline salt forms of mesembrine, also known as 3a-(3,4-dimethoxyphenyl)-octahydro-1-methy-6H-indol-6-one. Mesembrine has the chemical formula C17H23NO3. The invention further relates to the preparation of a novel crystalline salt of mesembrine and to the use of the mesembrine salt as a medicament. In one embodiment the novel crystalline salt form of mesembrine is mesembrine besylate salt.

The present application relates to a kind of water treatment agent and water treatment method of no steam water cyclone separator boiler, the water treatment agent of no steam water cyclone separator boiler includes: first amine, second amine, dispersing agent, auxiliary agent and solvent;The molecular weight of the first amine is less than the molecular weight of the second amine;The auxiliary agent includes dimethylformamide and / or benzene sulfonate.The water treatment agent provided by the present application, by adjusting the formula of water treatment agent, by the synergistic effect between each component in water treatment agent formula, so that after adding the water treatment agent in boiler water, it can be guaranteed that in the superhigh pressure boiler without design steam water cyclone separator, the saturated steam sodium ion in drum meets the requirement ≤1 μg / kg.

The invention belongs to the technical field of CO2 oil displacement, and particularly relates to a water-based slug for solubilizing residual heavy components, which comprises the following components in percentage by mass: 0.2 to 1.0 percent of component A, 0.1 to 0.5 percent of component B and 0.3 to 0.8 percent of component C, and the balance of water. The component A is a benzene sulfonate type anionic surfactant of which the para-position is provided with an alkyl chain, the component B is a sulfate type anionic surfactant of which the hydrophobic chain is provided with a plurality of propoxy groups and alkyl chains, and the component C is a sulfopropyl betaine type zwitterionic surfactant. The three effects of stripping, dispersing and solubilizing are synergistically exerted by means of different surfactants, after CO2 flooding is implemented, residual heavy components after CO2 flooding can be effectively solubilized, damage to a reservoir caused by the residual heavy components due to the fact that CO2 flooding tends to extract light components when CO2 flooding is carried out for a long time is avoided, and the recovery efficiency can be improved to a certain degree.

The present invention relates to a method for preparing a polyisobutyl benzene sulfonate comprising the steps of alkylation of benzene with a terminal unsaturated polyisobutene to produce a polyisobutyl benzene, sulfonation of the polyisobutyl benzene to produce a polyisobutyl benzene sulfonic acid, and neutralizing the polyisobutyl benzene sulfonic acid to produce a polyisobutyl benzene sulfonate. The invention also relates to the polyisobutyl benzene sulfonate, the polyisobutyl benzene sulfonic acid, the polyisobutyl benzene, and to a lubricant comprising the polyisobutyl benzene sulfonate, to a fuel comprising the polyisobutyl benzene sulfonate, and to a use of the polyisobutyl benzene sulfonate as lubricant additive or fuel additive.

The invention discloses a novel high-light-transmittance, high-tinting-strength and high-paint-adhesion color-developing and light-transmitting automotive interior and exterior light-emitting component and a preparation method thereof. The novel high-light-transmittance, high-tinting-strength and high-paint-adhesion color-developing and light-transmitting automotive interior and exterior light-emitting component mainly comprises the following raw materials in percentage by weight: 57-85% of polypropylene resin, 5-20% of high-light-transmittance filler, 10-20% of benzene sulfonate grafted SEBS polymer, 0.05-0.5% of anionic organic dye, 0.1- The core of the invention is that through molecular design, benzene sulfonate containing quaternary ammonium salt cationic groups is grafted on an SEBS polymer chain, so that the benzene sulfonate is combined with anionic dye through strong electrostatic interaction, and molecular-level dispersion and anchoring of the dye are realized; the problems of poor dispersity, easy migration, uneven tinting strength, poor weather resistance and the like of the dye in the light-transmitting polypropylene matrix in the traditional physical blending are fundamentally solved; the color developing substrate has the advantages of high light transmission and high tinting strength, and also can be endowed with a bright color effect.

The present invention relates to a process for the preparation of solid dispersion of 2-{4-[(3S)-Piperidin-3-yl] phenyl}-2h- indazole 7-carboxamide 4-methyl benzenesulfonate (1) with at least one pharmaceutically acceptable excipient.

The present invention relates to the besylate salt of 1-{4-[2-methyl-4-({1-[2-methyl-3-(trifluorome-thyl)phenyl]ethyl}amino) pyrido[3,4-d]pyrimidin-6-yl]-4-oxido-1,4-azaphosphinan-1-yl}ethanone, in any of its anhydrous forms or any hydrate(s), or mixtures thereof, its use for the treatment of disorders, and the use of the besylate salt for the preparation of a medicament.