100 results about "Benzenesulfonates" patented technology

The invention provides a method for improving the efficiency of a perovskite solar cell, and relates to the technical field of solar cells, the cell structure sequentially comprises a bottom substrate, a transparent electrode, a hole transport layer, a perovskite light absorption layer, an interface modification layer, an electron transport layer, a buffer layer and a metal electrode from bottom to top; a new additive 4-(2-aminoethyl) benzenesulfonic acid hydrochloride is introduced into the perovskite light absorption layer, the additive is introduced into the perovskite light absorption layer by being dissolved in a perovskite precursor solution, and the dosage of the additive is 0.1-1.5 mg / mL. Based on the method, the defect density of shallow energy level and deep energy level of perovskite is reduced, a more intrinsic perovskite absorption layer is formed through induction, balance extraction of electrons and holes is promoted, and then the open-circuit voltage and efficiency of the solar cell are remarkably improved.

The invention relates to a sterilizing, corrosion-inhibiting and scale-inhibiting foaming agent for foam drainage and a preparation method thereof, and belongs to the technical field of oil and gas development. The sterilizing, corrosion-inhibiting and scale-inhibiting foaming agent comprises the following components in percentage by mass: 1%-2% of a triazole bactericide, 3%-5% of a scale inhibitor, 0.2%-1% of polyvinyl alcohol, 10%-18% of a bis-imidazoline sulfonated quaternary ammonium salt zwitterionic surfactant, 5%-10% of benzene sulfonate, 5%-10% of Ninol and the balance of water. The foaming agent is good in foaming performance, the prepared foam liquid is stable in foam, very high in liquid carrying capacity and good in salt resistance, temperature resistance and oil resistance, compared with a foaming agent in the prior art, the foaming agent is better in performance, and the foaming agent is suitable for different oil and gas wells, shale gas wells and other environments. And besides foaming performance, the detergent also has excellent sterilization, corrosion inhibition and scale inhibition effects, realizes multiple effects by one agent, and is very strong in comprehensive performance.

The invention provides a perovskite photovoltaic cell, a preparation method thereof and a laminated cell, relates to the technical field of photovoltaics, and aims to solve the problem of low photoelectric conversion efficiency of the perovskite photovoltaic cell. The perovskite photovoltaic cell comprises a perovskite light absorption layer and a hole transport layer stacked on one side of the perovskite light absorption layer, the hole transport layer comprises a hole transport material and benzene sulfonate, and the hole transport material comprises nickel oxide, [2-(3, 6-dimethoxy-9H-carbazole-9-yl) ethyl] phosphonic acid, [4-(3, 6-dimethoxy-9H-carbazole-9-yl) ethyl] phosphonic acid, benzenesulfonate, and nickel oxide. The phosphonic acid is one or more of [3, 6-dimethoxy-9H-carbazole-9-yl) butyl] phosphonic acid, [6-(3, 6-dimethoxy-9H-carbazole-9-yl) butyl] phosphonic acid, and [6-(3, 6-dimethoxy-9H-carbazole-9-yl) hexyl] phosphonic acid. The perovskite photovoltaic cell improves the photoelectric conversion efficiency.

The invention discloses a method for removing metal impurities through electrolytic coupling vacuum distillation of tin benzene sulfonate. The method comprises the following steps: step 1, preparing a liquid; step 2, preparing an electrolyte; step 3, electrolysis; 4, copper removal and refining; and step 5, vacuum distillation. According to the method, the crude tin is prepared into the electrolyte, the benzene sulfonate is added for electrolysis, the precipitation potential of lead and tin is changed, the impurity lead element with high difficulty is removed, other impurity elements in the crude tin can also be removed, the lead, copper and other impurity elements are further removed by combining copper removal refining and vacuum distillation, and the 5N or 6N standard high-purity tin is obtained. The content of the lead element and the content of the bismuth element are both smaller than 1 ppm, the content of the uranium element and the content of the thorium element are both smaller than 1 ppb, the requirement of a low-alpha-ray-dose material is met, the problem that radioactive alpha-particle impurity elements in crude tin are difficult to remove through an electrolytic method is effectively solved, the use requirement that the high-purity tin serves as a welding flux is met, and the quality of a semiconductor chip is greatly improved.

The present invention addresses the problem of providing a high-quality solid preparation containing milobalin benzene sulfonate and having excellent storage stability. The solution of the present invention is a solid preparation for medical use, which contains milobalin benzene sulfonate and does not substantially contain a reducing sugar.

The invention discloses a hydrogenation device scale inhibitor for heavy high-sulfur raw oil and a preparation method of the hydrogenation device scale inhibitor, and relates to the technical field of scale inhibitors. The scale inhibitor is prepared from a polyisobutylene succinimide dispersing agent, a high-temperature-resistant scale inhibition dispersing agent, an anti-rust agent, an imidazoline corrosion inhibitor, an antioxidant, a sulfide chelating agent, a clearing agent, cup carbazole alkylbenzene sulfonate and a solvent in specific parts by weight. The preparation method comprises the following steps: heating the solvent to 80-100 DEG C, sequentially adding the other components, and stirring for 30-40 minutes. Aiming at the characteristics of heavy high-sulfur raw oil, the scale inhibitor realizes high scale inhibition rate, excellent high-temperature stability and strong sulfur corrosion resistance through a multi-component synergistic effect, effectively solves the problems of scaling and corrosion of a hydrogenation device, prolongs the operation cycle of the device, and is suitable for a hydrogenation process of high-sulfur and high-asphaltene raw oil.

The invention discloses a thiophanate-methyl wettable powder and a preparation method thereof, and belongs to the technical field of pesticides, the thiophanate-methyl wettable powder comprises the following raw materials by weight: 60-70 parts of a thiophanate-methyl active compound, 15-20 parts of modified kaolin, 5-10 parts of a surfactant, and 5-9 parts of a thickener; the surface active agent is composed of a nonionic surface active agent and a benzene sulfonate silicon-based surface active agent according to the mass ratio of 1: 1, aiming at the problem that the water solubility of the thiophanate-methyl is very poor, the thiophanate-methyl wettable powder is obtained by using the modified kaolin with better adsorption capacity as a carrier and cooperating with the surface active agent and the thickening agent, so that the thiophanate-methyl wettable powder can be used for preparing the thiophanate-methyl wettable powder. A verification test shows that the wetting time of the thiophanate-methyl wettable powder is less than or equal to 45s, the suspension rate is greater than or equal to 98%, and the thiophanate-methyl wettable powder has good wettability and dispersibility and can effectively play an insecticidal role.

A quinazoline derivative (represented by the formula (I)) salt's crystal form, a preparation method and application are provided; specifically, the hydrochloride crystal form A, B, C, D, F, H, I, Sulphate crystal form A, Maleate crystal form A, Succinate crystal form A, Adipate crystal form A, Glycolate crystal form A, Malate crystal form A, Fumarate Salt crystal form A, besylate crystal form A, B, C, benzoate crystal form A, hippurate crystal form A and oxalate crystal form A of the quinazoline derivative represented by formula (I). The salt crystal form provided by the present invention has good stability, which can be used in the treatment of non-small cell lung cancer brain metastasis, meningeal metastasis, primary brain cancer or glioma, etc., and has good bioavailability, which is of great significance for further research on the efficacy of such solid drugs.

The present invention relates to P2X3 inhibitor compounds and their salts, crystalline polymorphs and uses.The present invention provides the crystalline form of the compound of formula I with good medicinal properties.The present invention also obtains medicinal salts of the compound of formula I, and further obtains crystalline form products of salts, such as hydrochloride crystalline form A, maleate crystalline form A, p-toluenesulfonate crystalline form A, benzenesulfonate crystalline form A, malonate crystalline form A, etc., which has important significance for the development of effective therapeutic drugs.

The present invention relates to a liquid aqueous detergent composition comprising a surfactant system comprising a primary surfactant as an anionic surfactant and a secondary surfactant as an amphoteric surfactant and one or more enzymes, at the same time the surfactant system optionally comprises a hydrocarbyl benzene sulfonate or a derivative thereof, the amount of hydrocarbyl benzene sulfonate or a derivative thereof making up 25% by weight of the anionic surfactant, based on the total amount of anionic surfactant. The invention further relates to a method for cleaning stainless steel hard surfaces using the composition according to the invention and to the use thereof.

To provide crystalline forms of a C-C chemokine receptor type 4 antagonist.SOLUTION: There is provided the compound 2 - ((R) - 3 - (1 - (1 - ((R) - 1 - (2, 4-dichlorophenyl) ethyl) - 3 - (trifluoromethyl) - 1H - pyrazolor3, 4-b] pyrazin-6-yl) azetidin-3-yl) piperidin-1-yl) ethan-1-ol benzenesulfonate in crystalline form.SELECTED DRAWING: Figure 1

The invention discloses a heavy non-aqueous phase liquid pollution remediation precursor solution, a preparation method and a remediation method. The heavy non-aqueous phase liquid pollution remediation precursor solution comprises 5-10 parts by volume of a surfactant, 1-5 parts by volume of a cosurfactant and 80-90 parts by volume of water; the surfactant is prepared from the following components in parts by volume: 10 to 20 parts of an oleophylic nonionic surfactant, 10 to 20 parts of an oleophylic hydrophilic nonionic surfactant and 50 to 75 parts of a gemini type surfactant; the cosurfactant is one or a combination of two of alkenylene benzene sulfonate and thiourea. According to the precursor solution, a surfactant and a cosurfactant are mixed to form a microemulsion precursor solution, the microemulsion precursor solution is injected into an underground environment, and residual phase DNAPLs in an aquifer is used as an oil phase to form an in-situ microemulsion, so that the purpose of efficiently removing the DNAPLs is achieved.

A process for the conversion of methanol to olefins includes the steps of passing a feedstock comprising methanol to a fluidized bed reactor in contact with a catalyst to produce an olefin product, wherein the process at least partially deactivates the catalyst to form an at least partially deactivated catalyst; and passing spent catalyst from said at least partially deactivated catalyst to a regenerator for regeneration thereby forming regenerated catalyst and returning activated catalyst from said regenerated catalyst to said reactor via a regenerated catalyst line. An oxygen volume content in the gas-phase component at the outlet of the regenerated catalyst pipeline is controlled to be less than 0.1 percent, preferably less than 0.05% and more preferably less than 0.01% on the regenerated catalyst pipeline.

The present invention relates to a P2X3 inhibitor compound, a salt thereof, a polymorph thereof and use thereof. The present invention provides a crystalline form of a compound of formula I, which has good medicinal properties. A pharmaceutically acceptable salt of the compound of formula I is also obtained, and a crystalline form product of the salt is further obtained, such as a hydrochloride crystalline form A, a maleate crystalline form A, a p-toluenesulfonate crystalline form A, a benzenesulfonate crystalline form A, or a malonate crystalline form A. The present invention has great significance for developing effective therapeutic drugs.

The invention discloses a method for separating alkyne olefins with the same carbon number, which comprises the following steps: a mixed fluid containing the alkyne olefins with the same carbon number is contacted with crystalline porous organic salt with charge separation confinement channels, the crystalline porous organic salt selectively adsorbs alkyne in the mixed fluid, and the alkyne olefins with the same carbon number are separated; the molecular formula of the crystalline porous organic salt is (C25H16S4O12) (C6H16N2) 2, and the crystalline porous organic salt has a three-dimensional structure which is formed by connecting 4, 4 ', 4', 4 '-methane tetra-tetrabenzene sulfonate (C25H16S4O12) 4-and trans-1, 4-cyclohexanediamine cations (C6H16N2) 22 + through intermolecular ionic bonds. According to the method, the alkyne-olefin mixture with the same carbon number can be efficiently separated, the crystalline porous organic salt adsorbent is easy to regenerate, the hydrothermal stability is good, and self-repairing can be achieved under the mild condition.

The present invention relates to a method for efficiently producing a compound derived from the commercially available and readily available 3-((3S)-7-bromo-2-((2-hydroxypropyl)amino)-5-(pyridin-2-yl)-3H-benzo[e][1,4]diazepine-3-yl)propionate methyl ester, namely, the compound 3-[(4S)-8-bromo-1-methyl-6-(2-pyridinyl)-4H-imidazo[1,2-a][1,4]benzodiazepine-4-yl]propionate methyl ester benzenesulfonate (remimazolam besylate).

The present invention provides a mono-p-toluenesulfonate of (S)-(2-((5-chloro-2-((7-(pyrrolidin-1-yl)-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl)amino)pyrimidin-4-yl)amino)-5-(methoxymethyl)phenyl)dimethyl phosphine oxide, and a hydrate and a crystal form thereof. The crystal form of p-toluenesulfonate has a good stability, is easy to process, and has a high solubility.

The present invention relates to a process for the preparation of N-(5-chloropyridin-2- yl)-N'-[(1S,2R,4S)-4(N,N-dimethylcarbamoyl)-2-(5-methyl-4,5,6,7-tetrahydro [1,3] thiazolo[5,4-c] pyridine-2-carboxamido)cyclohexyl]oxamide, 4- methylbenzenesulfonate. It further relates to a process for the purification of N-(5- chloropyridin-2-yl)-N'-[(1S,2R,4S)-4(N,N-dimethylcarbamoyl)-2-(5-methyl-4,5,6,7- tetrahydro [1,3] thiazolo[5,4-c] pyridine-2-carboxamido)cyclohexyl]oxamide, 4- methylbenzenesulfonate is having purity greater than 99% by HPLC, preferably greater than 99.5% and more preferably 99.9% by HPLC.

Disclosed in the present invention are a salt of a nicotinate compound, a crystal of the salt, and a preparation method therefor and a use thereof. The salt is selected from benzenesulfonate, phosphate, sulfate, hydrochloride, and methanesulfonate of a compound represented by formula (I). The crystal is crystal form A of the benzenesulfonate of the compound represented by formula (I), crystal form B of the benzenesulfonate of the compound represented by formula (I), crystal form A of the phosphate of the compound represented by formula (I), crystal form A of the sulfate of the compound represented by formula (I), crystal form A of the hydrochloride of the compound represented by formula (I), crystal form A of the methanesulfonate of the compound represented by formula (I), crystal form B of the methanesulfonate of the compound represented by formula (I), or an amorphous form of the methanesulfonate of the compound represented by formula (I).

The present invention provides a long-acting broad-spectrum antibacterial and antiviral composition, wherein the raw materials include 1-6% of nanomaterials, 0.1-1% of alkylbenzene sulfonate, 1-2% of antiviral ingredients, 0-2% of surfactants, and the remainder of alkane oils according to weight percentage. The present invention provides a long-acting broad-spectrum antibacterial and antiviral composition and a preparation method thereof. The present invention significantly improves the softness of textiles through the combined action of suitable proportions of alkylbenzene sulfonate and surfactants. The present invention adds tea extract to the composition, which enables the textiles to have certain antiviral capabilities while having antibacterial properties. The long-acting broad-spectrum antibacterial and antiviral composition of the present invention can be applied to textiles, and the obtained fabrics have high-efficiency antibacterial properties, softness and wear resistance, which is of great significance for improving people's health and quality of life. The preparation method of the present invention is simple and convenient, has strong repeatability, and is conducive to large-scale production.

The present invention relates to the dihydrochloride and dibenzenesulfonate salts of the c-Met kinase inhibitor 2-fluoro-N-methyl-4-[7-(quinolin-6-ylmethyl)imidazo[1,2-b][1,2,4]triazine-2-yl]benzamide, and pharmaceutical compositions thereof useful in treating cancer and other diseases associated with dysregulation of kinase pathways. The present invention also relates to methods and intermediates for preparing 2-fluoro-N-methyl-4-[7-(quinolin-6-ylmethyl)imidazo[1,2-b][1,2,4]triazine-2-yl]benzamide and its salts.

The present invention discloses a preparation method of chiral 3-(N-methyl-1,2,3,4-tetrahydroisoquinoline) propionate benzenesulfonate, which comprises the following steps: (1) firstly, carrying out a nitrogen alkylation reaction on compound 4 and 3-chloropropionate, then carrying out an asymmetric reduction reaction under the action of a chiral catalyst, trichlorosilane and an auxiliary agent, and finally forming a salt with oxalic acid to obtain compound 5; (2) alkalizing compound 5 and then carrying out a quaternization reaction with methyl benzenesulfonate, and purifying the reaction product in a purification solvent to obtain the target compound 1. The method of the present invention has easily available raw materials, mild reaction conditions, low production cost, high purity of the obtained quaternary ammonium salt with a cis configuration, and can be used to prepare qualified cis-atracurium besylate.

The invention relates to a bimodal trigger intelligent diaphragm, a battery, a preparation method and application. The bimodal trigger intelligent diaphragm comprises a base film, and a thermal response layer and an electric response layer which are respectively positioned on two sides of the base film, the thermal response layer is prepared from the following raw materials in percentage by weight: 30 to 50 percent of capsule, 10 to 15 percent of PVDF-HFP and the balance of solvent; the capsule comprises a Wood alloy and a capsule wall wrapping the Wood alloy, the material of the capsule wall is polymethyl methacrylate, and the composition of the Wood alloy is Bi < 50 > Pb < 2. 7 > Sn < 1. 3 > Se < 0.5 > Cd10. The electric response layer is prepared from the following raw material components: 0.2 to 0.5 M of N-(4-sulfonyl butyryl) aniline, 0.6 to 1.5 M of sulfuric acid and 0.05 to 0.2 M of benzene sulfonate; according to the invention, dual protection is realized through thermal response and electrical response, the sensitivity, stability and response speed of thermal protection are effectively improved, and the protection effect is improved.

The invention relates to a benzene sulfonate compound for forming an organic film, a composition for forming an organic film, a method for forming an organic film, and a method for forming a pattern. The present invention addresses the problem of providing: a film which has excellent coating properties such as coating defects, film-forming properties, and embedding properties when an organic underlayer film for a multilayer resist is used; the present invention relates to a composition for forming an organic film, which uses a benzene sulfonate that does not belong to a perfluoroalkyl compound (PFAS) and is useful as a photoresist material, a pattern forming method using the same, and a compound suitable for the same. [Solution] A composition for forming an organic film, which is characterized by containing (A) a resin and / or a compound for forming an organic film, (B) a benzene sulfonate compound that is represented by formula (1) and that does not contain a perfluoroalkyl group, the molecular weight of the anionic moiety in the formula (1) being 200 or more, and (C) a solvent. In the formula, R1, n and A + are as defined herein.

The invention relates to a cisatracurium besilate process impurity and a synthesis method thereof. The structure of the cisatracurium besilate process impurity is shown as a formula I in the specification. The synthesis method comprises the following steps: 1) adding (1R, 2R)-1, 2, 3, 4-tetrahydro-6, 7-dimethoxy-2-[2-(t-butyloxycarbonyl) ethyl]-2-methyl-1-veratryl isoquinolinium benzene sulfonate into acetonitrile, and adding tert-butyl hydroperoxide to obtain an intermediate A; 2) adding the intermediate A into 70% benzenesulfonic acid, and hydrolyzing to obtain an intermediate B; and 3) adding the intermediate B and (1R, 2R)-1, 2, 3, 4-tetrahydro-6, 7-dimethoxy-2-(9-hydroxy-3-oxo-4-oxynonyl)-2-methyl-1-veratryl isoquinolinium benzene sulfonate into dichloromethane, carrying out reflux, after the reaction is finished, carrying out washing and drying, and carrying out preparation and separation to obtain the cisatracurium besylate process impurity. The impurity can be used as a reference substance for detecting cisatracurium besilate related substances, and is used for controlling the purity of a cisatracurium besilate bulk drug.

The present application relates to benzene sulfonate salts, phosphate salts, tartrate salts, fumarate salts, and succinate salts of mesembrine, also known as 3a-(3, 4-dimethoxyphenyl)-octahydro-1-methyl-6H-indol-6-one. And the mesembrine has a chemical formula of C17H23NO3. The present application also relates to pharmaceutical compositions comprising such salts and their medical uses. In one embodiment, the salt is mesembrine benzene sulfonate in crystalline form. A general process for preparing mesembrine salts is also disclosed. # imgabs0 #

The invention discloses a composite metal oxide desulfurizer as well as a preparation method and application thereof, and the preparation method comprises the following steps: dissolving a metal active component precursor salt and a precipitator in a solvent to obtain a mixed solution A; dissolving gemini benzene sulfonate in a solvent to obtain a mixed solution B; the mixed solution A and the mixed solution B are mixed and then placed in a closed environment without a carbon dioxide atmosphere, a hydrothermal reaction is conducted, and hydrotalcite compound crystals are obtained; roasting the hydrotalcite compound crystal to obtain powder; mixing the powder, a binder and a pore-enlarging agent, and performing extrusion forming to obtain the desulfurizing agent, the molar ratio of the metal ions to the precipitant to the gemini benzene sulfonate in the metal active component precursor salt is 1: (0.8-1.2): (0.1-0.4). No organic solvent is added, so that the method is simple and green; the prepared hydrotalcite compound is high in crystal crystallinity, and the desulfurization activity is enhanced.

Disclosed in the present invention are a crystal form of a benzene sulfonate containing a piperidine ring compound, and a preparation method therefor and the use thereof. Provided in the present invention is a crystal form A1 of compound (2). In an X-ray powder diffraction pattern (Cu-Kα radiation) of the crystal form at diffraction angles as represented by the 2θ angle, diffraction peaks appear at 5.971°±0.200°, 7.088°±0.200°, 12.068°±0.200°, 15.881°±0.200°, 20.557°±0.200° and 21.599°±0.200°. The crystal form can exist stably, and the content of isomer impurities as represented by formula (1') can be obviously reduced by means of crystal form preparation steps.