655results about "Sulfonic acid preparation" patented technology

The invention relates to the technical field of fracturing fluids, and discloses a preparation method of a temperature-resistant and salt-resistant fracturing fluid, which comprises the following steps: carrying out polymerization reaction on acrylamide, acrylic acid and an acrylamide sulfonic acid monomer to obtain a polymer thickening agent, and compounding the polymer thickening agent with a cross-linking agent, a clay stabilizer and the like to obtain the temperature-resistant and salt-resistant fracturing fluid. The polymer thickening agent contains long-chain alkyl, a physical cross-linked spatial network structure can be formed through a hydrophobic association effect, the hydrodynamic volume is increased, a good tackifying effect is achieved, and after high-speed shearing, the long-chain alkyl can be cross-linked again to form a spatial network structure, so that a solution still keeps very high apparent viscosity, and the viscosity of the solution is improved. Good anti-shearing performance is realized. The acrylamide sulfonic acid monomer contains a sulfonate group and is used as a temperature-resistant and salt-resistant monomer, so that the polymer thickening agent has good temperature resistance and salt resistance, and the fracturing fluid still keeps relatively high apparent viscosity after being subjected to high-temperature heat treatment and in formation water with high salinity.

The invention discloses a non-natural amino acid as well as a preparation method and application thereof. The novel non-natural amino acid is obtained by introducing long and soft side chain amino acid into a classical ASF side chain for the first time, the stability of the obtained non-natural amino acid is enhanced, the reaction radius of the non-natural amino acid is increased, the non-natural amino acid can touch amino acid residues with farther distance, and the reactivity is improved. In addition, compared with other covalent amino acids, the covalent amino acids have higher reaction rate and binding efficiency. The polypeptide and related drugs obtained based on the non-natural amino acid can be high in safety, can cross a blood brain barrier to realize brain targeting, and have better anti-tumor activity, so that the polypeptide and related drugs have extremely high medical value.

To provide a fluorinating agent that can be produced using a simple method, and a fluorination method that uses a fluorinating agent that can be produced using a simple method.SOLUTION: The present disclosure provides a fluorinating agent that comprises a fluorine-containing compound and fluoride ions.SELECTED DRAWING: None

The invention relates to the technical field of petroleum drilling fluids, in particular to a lubricant additive and a preparation method thereof, a lubricant, a water-based drilling fluid and a preparation method thereof, the lubricant additive comprises the following raw materials: 6 parts of taurine, 30-60 parts of 1-bromohexadecane, 8.5-15 parts of potassium hydroxide, 0.5-0.9 part of potassium iodide, 30-60 parts of thionyl chloride, 2-4 parts of N, N-dimethylformamide, 7-17 parts of ammonia water and 30 parts of trichloromethane. The lubricant additive takes sulfonic acid amine as an active adsorption group, and can be stably adsorbed on a drill stem, a sleeve and a mud cake. Meanwhile, two C16 flexible chains are arranged, a compact lubricating film can be formed, and friction resistance is efficiently reduced.

The invention discloses a method and a device for preparing CLT acid through pipeline type continuous catalytic hydrogenation reduction. According to the method, catalytic hydrogenation reduction reaction is carried out in the device. According to the method, equipment such as a five-stage static tubular mixer, a gas-liquid separation tank and a reduction liquid temporary storage tank is adopted, so that efficient hydrogenation reduction of the CLT acid nitride is realized. In the reaction process, hydrogen is proportionally introduced by stages through a grading mixer, the hydrogen pressure is controlled to be 0.8-1.0 MPa, and the reaction temperature is controlled to be 70-80 DEG C. The used platinum-carbon catalyst is not recycled and recycled after being filtered and recycled, so that the loss of precious metal platinum is effectively reduced. Through the method, the reduction efficiency of CLT acid is remarkably improved, the generation amount of byproducts and dechlorination products is low, and the nitro conversion rate reaches 99.90% or above. The method has the advantages of small equipment volume, short reaction time, high reaction stability and selectivity, and low catalyst cost.

The invention belongs to the technical field of sulfonamide synthesis, and particularly relates to a green and environment-friendly sulfonamide amidation preparation method. Comprising the following steps: adding chlorosulfonic acid into a reactor, stirring, heating, adding o-nitrochlorobenzene, carrying out staged heat preservation, cooling, and adding thionyl chloride to obtain 2-nitro-4-chlorine sulfonate-chlorobenzene; the method comprises the following steps: separating and filtering 2-nitro-4-chlorine sulfonate-chlorobenzene, adding ammonia water, stirring, preserving heat, and carrying out filter pressing to obtain 2-nitro-4-amine sulfonate-chlorobenzene; the preparation method comprises the following steps: adding liquid caustic soda into 2-nitro-4-amine sulfonate-chlorobenzene, stirring, heating, and adjusting the pH value to obtain 2-nitro-4-amine sulfonate-phenol; the method comprises the following steps: adding water, a catalyst and hydrazine hydrate into 2-nitro-4-amine sulfonate-phenol, heating, stirring, and carrying out filter pressing to obtain 4-sulfonamide-2-amino-phenol. According to the preparation method of sulfonamide, generated tail gas is subjected to falling film absorption treatment, and the product prepared by the preparation method is high in purity.

The invention provides a preparation method of 1, 3-propane sultone, which comprises the following steps: introducing an allyl alcohol aqueous solution, a sodium hydroxide aqueous solution, sulfur dioxide and a slow-release peroxide into a continuous fluid reactor, reacting to obtain a 3-hydroxy propane sodium sulfonate crude product, acidifying the crude product to obtain 3-hydroxy propane sulfonic acid, concentrating to remove water, separating out salt by using methanol, and filtering to obtain 1, 3-propane sultone. And finally carrying out reduced pressure distillation on the filtrate to obtain 1, 3-PS. The slow-release peroxide is used for replacing conventional hydrogen peroxide or benzoyl peroxide to serve as an initiator, the preparation process conditions of the slow-release peroxide are controlled, calcium peroxide is embedded through stearic acid firstly, then surface modification polydopamine is subjected to secondary embedding, and the slow-release peroxide of a special structure is obtained; the selectivity of the 3-hydroxypropane sodium sulfonate is obviously improved while the reaction efficiency is not excessively influenced, and the method has industrial advantages.

The invention relates to a method for preparing methylsulfonyl fluoride from methylsulfonyl chloride, which comprises the following steps: by taking methylsulfonyl chloride as a raw material, adding a fluorination catalyst and anhydrous hydrogen fluoride as a fluorinating agent, and continuously reacting in an HL microchannel reactor to prepare methylsulfonyl fluoride, the HL microchannel reactor is of a three-stage nested microchannel structure, a first-stage mixing area is a conical spiral channel, a second-stage reaction area is a snakelike corrugated channel, and a third-stage extension area is a straight channel. The reaction rate is high, the unit consumption of anhydrous hydrogen fluoride serving as a fluorinating agent is low, the raw material cost is saved, the preparation cost is greatly reduced, and compared with a conventional tank reactor, the HL microchannel reactor is high in reaction rate, convenient to clean, capable of saving manpower, capable of achieving continuous preparation and convenient to achieve large-scale industrialization.

The invention belongs to the technical field of fine chemical organic synthesis, and discloses a synthesis method of 1, 3-propane sultone without generation of three wastes. The synthesis method comprises the following steps: by taking allyl alcohol, sulfite and hydrosulfite as raw materials, generating 3-hydroxy propanesulfonate; then removing part of water, adding a solvent A to separate out sulfite, filtering, and adding sulfuric acid into filtrate for acidification; and adding a solvent B to separate out sulfate, filtering and separating out the sulfate, and adding a dehydrating agent to carry out dehydration cyclization reaction to prepare the 1, 3-propane sultone. According to the synthesis method provided by the invention, a 1, 3-propane sultone product with the yield not lower than 95% and the purity reaching 99.9% or above and a sulfate byproduct with the purity reaching 99.6% or above can be obtained; no waste gas, waste solid or waste water is generated in the reaction process, the catalyst sulfite can be repeatedly used, and the used solvent is easy to recover and can be repeatedly used.

The invention discloses a biphenyl derivative photoinitiator, a preparation method of the biphenyl derivative photoinitiator, a photocuring thin film material and a preparation method and application of the photocuring thin film material. The biphenyl derivative has a structural formula shown as a formula (I), R1 is an electron donor group, and R2 is an electron acceptor group. According to the invention, biphenyl is taken as a main body structure, different donor groups R1 and acceptor groups R2 are connected, the photoinitiator is synthesized through Suzuki reaction, and a polymeric monomer material is N, N-dimethylacrylamide (DMA). The photocuring material with long afterglow luminescence can be obtained through an ultraviolet irradiation method, and under the irradiation of a 365nm ultraviolet lamp, an initiator absorbs photons to generate active species to attack double bonds in a monomer to initiate a polymerization reaction. The light-cured film can generate long afterglow luminescence as long as several seconds after being illuminated, and can be applied to the aspects of counterfeiting prevention, 3D printing, photoetching and the like.

The invention provides a method for repairing an electric return lead-acid storage battery by using a zwitter-ion additive, which comprises the following steps of: preparing the zwitter-ion additive with sulfonic acid group and amino group, and compounding the zwitter-ion additive with conductive carbon with acidified surface to prepare repairing liquid; opening an upper cover plate and a safety valve of the battery, adding a certain amount of deionized water, standing, and extracting redundant flowing liquid; after a certain amount of repairing liquid is added, low-current charging is adopted, and electrified pumping is in a barren solution state; the steps are repeated, overcharging is carried out with smaller current, and stopping is carried out; and then the battery air hole cover is reset and fixed again. And finally, testing the repaired battery, and checking the repairing effect. The method can solve the problems that the residual capacity of the returned lead-acid storage battery for electric power is high, and resources are wasted when the lead-acid storage battery is directly subjected to hazardous waste treatment; and meanwhile, the updating frequency of the lead-acid storage battery for power is reduced, and the power operation cost is reduced.

The invention provides a continuous production method of 2-acrylamido-2-methylpropanesulfonic acid and application of the 2-acrylamido-2-methylpropanesulfonic acid. The continuous production method comprises the following steps: S1, adding part of acrylonitrile into a reaction kettle in advance; s2, continuously adding the residual acrylonitrile into the mixing kettle, adding a pre-prepared fuming sulfuric acid solution, mixing, and controlling the mixing temperature at-10-10 DEG C to obtain a first mixed solution; s3, continuously adding the first mixed solution obtained in the step S2 into a supergravity reactor, gasifying isobutene at a constant speed, and introducing the gasified isobutene into the supergravity reactor for reaction to obtain a second mixed solution containing 2-acrylamido-2-methylpropanesulfonic acid; and S4, adding a second mixed solution containing 2-acrylamido-2-methylpropanesulfonic acid into the reaction kettle, continuously reacting, and after the reaction is finished, filtering and drying to obtain the 2-acrylamido-2-methylpropanesulfonic acid. The 2-acrylamido-2-methylpropanesulfonic acid prepared by adopting the production method is high in purity and high in product synthesis efficiency, and meanwhile, rectifying still residues generated in the reaction process are relatively low.

The invention belongs to the technical field of energetic plasticizer preparation, and particularly discloses a method for preparing N-butyl nitroxyethyl nitramine through ionic liquid nitration. The method comprises the following steps: mixing an ionic liquid nitrating agent with butyl ethanolamine to obtain a mixed solution; and mixing the mixed solution with a catalyst and acetic anhydride, reacting, and carrying out post-treatment to obtain the N-butyl nitroxyethyl nitramine. According to the method, the ionic liquid with stable properties is adopted as the nitrating agent, the reaction is mild when the ionic liquid is mixed with the butylethanolamine, violent heat release caused when fuming nitric acid is in contact with the butylethanolamine is effectively avoided, and the ionic liquid precursor can be recycled through simple extraction after the reaction.

The invention relates to the technical field of surfactants, and particularly discloses a preparation method and application of a sulfosuccinate type surfactant, and the preparation method specifically comprises the following steps: (1) esterification reaction: under the protection of inert gas, adding fatty alcohol and carboxylic acid anhydride, introducing gas for 10-20 minutes, adding a difunctional acidic site catalyst, heating to 95-105 DEG C, and reacting for 2-3 hours to obtain an esterification product; and (2) sulfonation reaction: cooling the esterification product to 70-80 DEG C, dropwise adding 20-40wt% of sulfonating agent aqueous solution, preserving heat for 1-2 hours after dropwise adding, and then performing post-treatment to obtain the sulfosuccinate type surfactant. In the preparation process, one-pot preparation is realized by regulating and controlling process conditions and developing a catalyst to efficiently catalyze esterification and sulfonation, intermediate products do not need to be separated between esterification and sulfonation, material loss caused by transfer and separation is avoided, the adopted catalyst can be used for inhibiting premature oxidation of a sulfur source in the sulfonation process, and the sulfonation efficiency is improved. The generation of byproducts is reduced, and the yield is improved.

The invention relates to the technical field of pesticide acaricides, in particular to a preparation method of a trifluoroethyl sulfoxide substituted aryl compound and an intermediate of the trifluoroethyl sulfoxide substituted aryl compound. According to the preparation method, cheap substituted benzene is taken as an initial raw material, sulfonation, reduction, alkylation and nitration oxidation are carried out to prepare an m-nitro-substituted trifluoroethyl sulfoxide benzene compound, then nitro is reduced into amino, and an intermolecular substitution splicing reaction is carried out to prepare the trifluoroethyl sulfoxide substituted aryl compound with high yield. The preparation method is short in step, simple and convenient to operate, environment-friendly, low in cost, high in yield and more suitable for large-scale industrial production. The invention also relates to the m-nitro-substituted trifluoroethyl sulfoxide benzene compound and a preparation method thereof.

The invention belongs to the technical field of oil exploitation, and particularly relates to a foaming agent for nitrogen foam fracturing and a preparation method and application thereof. The preparation method comprises the following steps: adding 2, 4, 6-trimethyl-3, 5-diaminobenzene sulfonic acid, xylene and a catalyst into a high-pressure reactor, fully stirring, purging a pipeline and a reaction kettle with nitrogen for 5-10 minutes, vacuumizing, stirring, heating to 70-80 DEG C, stopping vacuumizing, adding epoxypropane, heating to 170-190 DEG C, reacting for 2-10 hours, and cooling the system to 70-80 DEG C; continuously stirring the mixed solution, introducing ethylene oxide, heating to 180-200 DEG C after the ethylene oxide is completely introduced, continuously reacting, and cooling the system to room temperature; and adjusting the pH value to 8-9 with hydrochloric acid, filtering, and carrying out reduced pressure distillation to obtain a viscous solid, namely the foaming agent product. The foaming agent has the advantages of large foaming volume and long half-life period.

The invention belongs to the technical field of pesticides, and particularly relates to azobenzene calix [4] arene derivatives as well as a preparation method and application thereof. The invention discloses a novel azobenzene calix [4] arene derivative prepared by directional modification through an azo reduction reaction based on a calix [4] arene skeleton. The azobenzene calix [4] arene derivative has the characteristics of green environmental protection, accurate and controllable structure and efficient synthesis. After the derivative and a pesticide form a host-guest compound, the activity of the pesticide can be remarkably improved, the bioavailability of the pesticide at an action site is increased, the problem of low efficiency of the traditional pesticide is effectively solved, and the development of target drug resistance is delayed. The technology breaks through the technical bottleneck of nano-carrier environmental toxicity, provides a new thought for developing a multi-target and low-environmental-risk pesticide synergist, and has important significance for realizing pesticide decrement, synergism and resistance treatment.

The present invention relates to a disulfonate compound, a preparation method thereof, an electrolyte, and an energy storage device. The disulfonate compound has an #imgabs0# structure and is applied as an additive to an energy storage device, so that a stable SEI film can be formed on the negative electrode surface of the energy storage device, which can inhibit the decomposition of the solvent in the electrolyte. Since a stable SEI film can be formed on the negative electrode surface, the insertion and deintercalation of lithium ions at low temperatures become smooth, thereby improving the low-temperature performance of the energy storage device. On the other hand, the sulfonate group in the disulfonate compound can coordinate with transition metal ions to form a complex, passivating the positive electrode surface, inhibiting the dissolution of positive electrode metal ions, and reducing the decomposition effect of high-oxidation active substances on the solvent, thereby improving the electrochemical performance of the energy storage device under high-temperature conditions. In the energy storage device, the disulfonate compound can inhibit the increase of DC internal resistance, thereby improving the high-temperature performance and low-temperature performance of the energy storage device.

The invention belongs to the technical field of oil-gas field development, and particularly relates to a foaming agent and a synthesis method and application thereof. The synthesis method comprises the following steps: adding 1-amino-3, 6, 9, 12, 15, 18-hexaoxaheneicosan-21-acid and ethanol into a high-pressure reaction kettle, stirring and dissolving, adding 4-(2-bromoethyl) sodium benzenesulfonate, continuously stirring, adjusting the pH value to 8-9 by using sodium hydroxide, heating and preserving heat, and adjusting the pH value to 8-9 by using sodium hydroxide during the period; and adding bromotetradecane into the solution, heating and refluxing, adjusting the pH value to 8-9 by using sodium hydroxide during heating and refluxing, carrying out reduced pressure distillation to obtain a viscous solid, and recrystallizing by using normal hexane to obtain a product, namely the foaming agent. The foaming agent provided by the invention has the advantages of strong foaming power, good stability and low interfacial tension.

The invention relates to the technical field of perfluorononenoxy sodium benzenesulfonate, and discloses a reaction kettle for production of perfluorononenoxy sodium benzenesulfonate, the reaction kettle comprises a support, the end face of the support is fixedly connected with a shell, the end face of one end, far away from the support, of the shell is fixedly connected with a sealing cover, and the end face of the other end of the shell is fixedly connected with a reaction kettle body. A top cover is fixedly connected to the end face of the end, close to the sealing cover, of the support, a feeding port is fixedly connected to the end face of the top cover, a discharging port is fixedly connected to the end face of the end, away from the shell, of the support, and an engine is arranged on the surface of the discharging port. When the device runs, materials needing to be used are poured into the device through the top cover and the feeding port, at the moment, in the stirring component, the engine is started to drive the output shaft to rotate, when the output shaft rotates, the periodic toothed plate can be driven to rotate, and when the periodic toothed plate rotates, the rack can be driven to run periodically; when the rack moves, the rack drives the connecting sliding plate to periodically slide along the surface of the sliding rod, and meanwhile, when the rack moves, the rack drives the transverse rod to move.

The invention relates to the technical field of laundry detergents, and discloses a laundry detergent containing a modified gemini quaternary ammonium salt surfactant and a preparation method thereof.The laundry detergent is prepared from iminodiacetonitrile, cardanol glycidyl ether, 1, 8-dibromooctane, Raney Ni, 1, 3-propane sultone, brominated alkane and the like as raw materials through a one-step method. The modified gemini quaternary ammonium salt surfactant is obtained through an epoxy ring-opening reaction, a quaternization reaction, a reduction reaction, a ring-opening alkylation reaction and a substitution reaction. The preparation method comprises the following steps: adding alkyl glycoside and the modified gemini quaternary ammonium salt surfactant into deionized water, uniformly stirring and mixing, adding alkaline protease and the like, and stirring and mixing to obtain the laundry detergent containing the modified gemini quaternary ammonium salt surfactant. Tests prove that the laundry detergent prepared by the invention has better dirt-removing power and antibacterial effect.

The invention provides a preparation and purification method of a p-xylylene dicamphor sulfonate crystal form, which comprises the following steps: carrying out condensation polymerization on camphorsulfonic acid and terephthalaldehyde under the action of organic alkali to prepare p-xylylene dicamphor sulfonate, carrying out post-treatment, dissolving, clarifying and layering, dropwise adding ethanol, and sequentially carrying out first crystal growing and second crystal growing to obtain the p-xylylene dicamphor sulfonate crystal form. The preparation method comprises the following steps: dissolving p-xylylene dicamphor sulfonate in water to obtain a crude product of the p-xylylene dicamphor sulfonate crystal form, decolorizing the crude product, and carrying out gradient cooling crystallization, so that the high-purity p-xylylene dicamphor sulfonate crystal form product with high yield can be prepared, the content of impurities in the product is effectively controlled, the irritation of the impurities to the skin is reduced, and the safety of the product is improved. Meanwhile, the product has a crystal form, the moisture absorption of the product can be improved, and storage is easy.

The present application relates to a kind of shiff base metal complex liquid desulfurizer and its preparation method and use, by amine and aldehyde condensation preparation the structure in the shiff base ligand containing C=N double bond, the lone pair electron of nitrogen atom on shiff base and metal atom are mutually cooperated to form shiff base metal complex, under the condition of oxygen or air as activating agent, the catalyst can be oxidized into inorganic sulfur with organic sulfur.The shiff base metal complex liquid desulfurizer of the present application is synthesized by low-cost raw material, without adding desulfurizer in the desulfurization process, solve the problems such as large amount of existing desulfurizer, need to be added continuously.At the same time, the desulfurizer is liquid desulfurizer, increase the contact area with organic sulfur gas, improve the desulfurization efficiency, the desulfurization rate of methyl mercaptan is higher than 99%.

The present invention relates to a method for producing p-xylylenedicamphor sulfonic acid, and more specifically, to a method for producing p-xylylenedicamphor sulfonic acid from p-xylylenedicamphor sulfonate through a step of producing a p-xylylenedicamphor sulfonyl intermediate compound. The method for producing p-xylylene dichorsulfonic acid according to the present invention is performed by a synthesis reaction and thus theoretically has a conversion rate of 100% from a salt to an acid. According to the method, the problems in the prior art are solved, so that ion exchange resin does not need to be used, the cost of using the ion exchange resin is reduced, and acidic waste generated in the regeneration process of the ion exchange resin is not generated. In addition, the method has the advantages of excellent yield and mass production.

The application belongs to the field of fine chemical industry and environmental protection, and particularly relates to a method for preparing metal triflate by using high gravity reaction. The method comprises the following steps: 1, using trifluoromethylsulfonyl chloride and anhydrous HF gas as raw materials to generate trifluoromethylsulfonyl fluoride gas; 2, performing gas-liquid contact reaction of the trifluoromethylsulfonyl fluoride gas with an alkali metal solution to obtain a mixed solution; 3, performing solid-liquid separation on the mixed solution by using a filter press, and the liquid phase is a triflate salt solution; 4, drying the triflate salt solution by using a spray dryer to obtain a solid-phase product triflate salt. The method uses trifluoromethylsulfonyl chloride and anhydrous HF as raw materials to replace triflic acid in the traditional method, and utilizes high gravity reaction, so that the production cost is greatly reduced. The process is simple, the obtained product triflate metal salt has low impurity content, is superior to the industry standard, the process is zero emission, and has good economic value and social value.

The invention belongs to the technical field of detergents, and particularly relates to a preparation method of a composite fluorescent whitening agent. The method comprises an acylation reaction, a sulfonation reaction, a carbonyl reduction reaction, a dehydration reaction and a sulfonic acid salification reaction. Compared with a commercially available fluorescent whitening agent such as CBS, the composite fluorescent whitening agent synthesized by the preparation method disclosed by the invention has similar application effects, but the preparation process disclosed by the invention is simple, low in cost, environment-friendly in route and environment-friendly in working environment.

The invention belongs to the technical field of production processes of chemical products, and relates to a device and a method for continuously preparing 2-acrylamido-2-methylpropanesulfonic acid. The annular pipeline reaction system comprises a crystallization reactor, a tubular reactor group and a mother liquor internal circulation pipeline which form an annular passage; the solid-liquid separation refining system comprises a solid-liquid separation device, a reduced pressure distillation device, a product refining device, a drying device and a heat exchanger; the external circulation and feeding system comprises a mother liquor external circulation pipeline, an isobutene feeding pipeline, a sulfuric acid feeding pipeline, an acrylonitrile feeding pipeline and an acrylonitrile reflux pipeline; the acrylonitrile feeding pipeline is divided into three branches, one branch is connected with the crystallization reactor, one branch is converged with the isobutene feeding pipeline, the mother liquor external circulation pipeline and the acrylonitrile backflow pipeline to be connected with an isobutene feeding port, and the other branch is converged with the sulfuric acid feeding pipeline, the mother liquor external circulation pipeline and the acrylonitrile backflow pipeline to be connected with a sulfuric acid feeding port. According to the invention, the production efficiency is improved, and the yield and purity of the product are higher.

The invention discloses a compound and a synthesis method thereof, the synthesis method of the compound takes heptafluorobutanol as a raw material, and the compound is synthesized through five-step reaction, and the synthesis method comprises the following synthesis steps: S1, taking heptafluorobutanol as the raw material, and carrying out esterification reaction with benzene sulfonyl chloride to obtain an intermediate 1; s2, carrying out substitution reaction on the intermediate 1 to obtain an intermediate 2; s3, carrying out substitution reaction on the intermediate 2 to obtain an intermediate 3; s4, adding inorganic acid into the intermediate 3, dropwise adding a NaClO solution, and reacting to obtain an intermediate 4; and S5, carrying out fluorination reaction on the intermediate 4 to obtain the compound heptafluorobutanol sulfonyl fluoride. According to the synthesis method of the compound, heptafluorobutanol is used as a starting raw material, heptafluorobutanol sulfonyl fluoride is obtained through five-step reaction, use of a dangerous material hydrogen fluoride is avoided, special equipment is not needed, production is safer, and industrial production is more facilitated.

The invention discloses a preparation method of 2-oxo-4-phenyl oxazine sulfonyl fluoride, and belongs to the field of organic chemical synthesis. According to the method, in a specific tetrahydrofuran solvent, a cinnamyl (fluorosulfonyl) carbamate compound is used as a substrate and reacts under the action of a catalyst and alkali, and the 2-oxo-4-phenyl oxazine sulfonyl fluoride compound is obtained through the reaction. According to the method, iodobenzene diacetic acid and potassium tert-butoxide which are low in price and easy to obtain are adopted as the catalyst and alkali respectively, the substrate applicability is wide, the raw materials are simple and easy to obtain, the economic cost is low, and the target product can be obtained with the good yield.