30results about How to "Improve binding efficiency" patented technology

The utility model provides a kind of human resource management archives auxiliary threading device, it is related to the technical field of archives management, including base, left stand plate, first sliding slot, first bearing, first lifting plate, screw rod, hand wheel, upper antiskid block, lower antiskid block, arc hole and punch assembly etc.;Traditional manual binding needs page by page alignment, manual punching, for the archives of greater thickness, it is cumbersome and time-consuming to operate.And the device realizes automatic punching through punch assembly, multiple drill bits can work simultaneously, and punching operation of multiple hole positions is completed at one time, which greatly reduces the punching time and significantly improves the overall efficiency of archives binding.Operators do not need to repeat punching, threading and other mechanical actions, effectively reducing hand fatigue caused by long-term operation, reducing the work failure rate and reducing labor intensity.

The utility model discloses a mechanical ventilation newborn restraint belt belongs to restraint belt field. A mechanical ventilation newborn restraint belt, including main body pad, the both sides of main body pad are close to the end part and are installed with first trunk band and second trunk band respectively, the bottom of first trunk band is equipped with second magic tape wool surface, the top of second trunk band is equipped with the second magic tape hook surface cooperation of second magic tape wool surface main body pad's both sides close to the middle part are equipped with two connecting belts, and the arm band is slidably installed on the connecting belt, the utility model discloses a main body pad and the first trunk band and the second trunk band and the arm band and lower limbs connecting belt that are connected with main body pad are set up, and when using, can conveniently and fastly restrain the upper body and the limbs of newborn, can adjust the activity range of newborn through the arm band and lower limbs connecting belt after restraint, improve the comfort degree, and simple and convenient operation improves the restraint efficiency.

The application discloses a floor beam steel bar automatic binding machine and a binding method thereof. In the application, a three-dimensional moving mechanism drives a mounting rack to move, two extrusion mechanisms are arranged on the mounting rack, a shearing mechanism is arranged in front of the two extrusion mechanisms, a screwing mechanism is arranged below the shearing mechanism, and two guide assemblies are arranged in front of the screwing mechanism; two binding wires are conveyed to the two blades of corresponding shearing tongs of the shearing mechanism through the two extrusion mechanisms, enter arc-shaped guide rails one of the corresponding guide assemblies, are bent and guided in the arc-shaped guide rails one to enter arc-shaped guide rails two of the guide assemblies, are bent and guided in the arc-shaped guide rails one to return to the corresponding arc-shaped guide rails one, and are sheared by the shearing mechanism until a preset number of turns are wound on the cross rib, and the screwing mechanism screws the two binding wire turns wound on the cross rib. The application can replace manual work to realize the binding of the steel bar placed in the vertical direction, reduces the labor force, the binding mode is simple, and the binding efficiency is improved.

This application provides a device binding method. The method includes: A user terminal collects a signal at a collection position, generates a first signal fingerprint, and sends the first signal fingerprint and a corresponding first account to a server. An intelligent terminal collects a signal at a set position, generates a second signal fingerprint, and sends the second signal fingerprint and a corresponding device identifier of the intelligent terminal to the server. The server determines that the second signal fingerprint matches the first signal fingerprint, to determine that the second signal fingerprint is corresponding to the first account. The server binds the intelligent terminal to the first account based on a correspondence between the second signal fingerprint and the device identifier of the intelligent terminal. In this application, efficiency and accuracy of binding the intelligent terminal to the first account are improved.

The disposable circumcision anastomat comprises an inner ring and a binding wire assembly, a ring wire groove is formed in the surface of the inner ring, the binding wire assembly comprises a pull ring, a rope pushing device and a binding wire, the inner side of the inner ring is attached to the glans penis, the outer side of the inner ring abuts against prepuce tissue, the glans penis and the prepuce tissue are separated, and the binding wire is arranged in the ring wire groove. The binding wire can be arranged on the outer side of the inner ring in a sleeving mode, the pull ring is pulled, the rope pusher can tighten the binding wire on the loop line grooves and promote the binding wire to bind the prepuce tissue to the positions of the inner loop line groove and the outer loop line groove, the prepuce tissue to be cut is supported through the arranged inner ring, and then the prepuce tissue to be cut is cut by pulling the pull ring. And the rope binding device is driven to tightly fix the foreskin tissue outside the inner ring on the ring line groove, so that the effects of quickly binding and blocking blood are achieved, and the binding efficiency is improved.

The utility model discloses a book cover binding device for printing, which comprises a binding table and book covers stacked on the binding table, positioning plates are arranged around the book covers, a suction mechanism is arranged right above the book covers, and a lifting cylinder for driving the suction mechanism to lift is connected to the binding table in a swinging manner. The suction mechanism comprises a flexible suction cup for creating sealing conditions, a round pipe for limiting airflow, a sealing rubber block for controlling the airflow, a drawing and inserting rod for pulling the sealing rubber block and a motor for controlling the drawing and inserting rod to move. By arranging a mounting block and a connecting rod, lifting of a suction mechanism is conveniently controlled, book covers are conveniently sucked, by arranging a driving screw rod, a limiting rod and a drawing and inserting rod, air pressure in a round pipe is conveniently controlled, a flexible suction cup has the suction effect, and therefore the binding device for printing has the effect of stably transferring the book covers; and the purpose of improving the binding efficiency is further achieved.

The utility model relates to the technical field of carton binding, in particular to binding equipment for packaging carton processing. According to the technical scheme, the device comprises a bottom plate, a supporting plate, a limiting frame, a top plate and a connecting plate, the lower end of the supporting plate is fixed to the middle of one end of the upper end face of the bottom plate, one end of the lower end face of the top plate is fixed to the upper end of the supporting plate, a hydraulic cylinder is fixed to the middle of the upper end, and a hydraulic rod is movably installed at the lower end of the hydraulic cylinder; the lower end of the hydraulic rod is fixed to the middle of the upper end face of a connecting plate, three nail tongues are fixed to the middle of the lower end face of the connecting plate at equal intervals, fixing plates are fixed to the middles of the two ends of the lower end face of the top plate, and the connecting plate is located between the two fixing plates. The lower ends of the two fixing plates are fixed to the upper sides of the two ends of the limiting frame, and the width of the fixing plates is smaller than the length of the outer side of the limiting frame. The nailing machine has the advantage that a plurality of nails can be simultaneously nailed at the same time.

The application provides a box girder mesh assembling device and method for completing angle adjustment in the air, which comprises a bottom rib platform and a splicing platform, two splicing platforms are arranged on the two sides of the bottom rib platform and reciprocate along the width direction of the bottom rib platform, a splicing support is arranged above the splicing platform, the splicing support has an inclined assembly surface corresponding to the inclination angle of the box girder web plate, a travelling crane, the travelling crane is a square truss corresponding to the web plate reinforcement mesh and the top plate reinforcement mesh, hooks corresponding to the reinforcement mesh are arrayed on the lower surface of the travelling crane, a lifting mechanism is connected above the travelling crane in a hinged manner, an angle adjusting device is arranged between the lifting mechanism and the travelling crane, the reinforcement mesh is first bound by the mechanical equipment, the reinforcement binding efficiency is improved, the web plate reinforcement mesh after the binding is completed is subjected to angle adjustment by the travelling crane, then the splicing trolley is used for splicing, the structure is simple, the splicing efficiency is high, and the production efficiency of the reinforcement cage can be greatly improved.

The invention discloses an immunomagnetic composite material and application thereof in a neurofilament light chain protein kit. The preparation process of the immunomagnetic composite material comprises the following steps: preparing Fe3O4 nanoclusters by a hot solvent method, coating the Fe3O4 nanoclusters with dense silicon oxide to obtain silicon oxide magnetic beads, preparing mesoporous silicon oxide magnetic beads by a template method, carboxylating the mesoporous silicon oxide magnetic beads, and preparing the immunomagnetic composite material. The surface of the carboxylated mesoporous silica magnetic bead is coated with a neurofilament light-chain protein capture antibody to obtain the immunomagnetic composite material. The immunomagnetic composite material is used in a mesoporous magnetic particle chemiluminescence detection neurofilament light-chain protein kit for neurofilament light-chain protein detection, has the characteristics of low detection limit, good specificity, high sensitivity, simplicity, convenience and feasibility, and is suitable for large-scale and batch sample detection.

The invention provides a recarburization and acid reduction method for strengthening formation of brick red soil mineral binding state organic carbon. The recarburization and acid reduction method comprises the following steps: S1, constructing a functional microbial population; S2, activating and modifying minerals; S3, preparing a multi-layer gradient coating composite preparation; according to the invention, a synergistic construction method of'functional strain selection + specific phage regulation 'is adopted for the first time, and the selected strains are all strains with strong adaptability to the laterite acidic habitat, and can simultaneously realize multiple functions of microbial residual carbon formation, extracellular polymeric colloid synthesis, iron reduction coprecipitation and the like. According to the method, multiple targets of efficient enrichment of mineral binding state organic carbon, especially short-sequence mineral binding state organic carbon, remarkable improvement of soil pH, great increase of corn yield and the like are achieved at the same time, comprehensive benefits are remarkable, and the method is environmentally friendly and high in sustainability.

The utility model relates to the technical field of building construction, and discloses a profiled steel sheet additional steel bar positioning structure which comprises a bottom groove formed in a profiled steel sheet, a plurality of sets of cushion blocks are arranged in the bottom groove, the cushion blocks are perpendicular to the extending direction of the bottom groove, and the length of the cushion blocks is matched with the width of the bottom groove. A positioning groove is formed in the top of the cushion block and used for containing an additional steel bar, and the direction of the positioning groove is consistent with the extending direction of the bottom groove. Binding grooves are formed in the cushion blocks, binding wires are arranged in the binding grooves in a penetrating mode and used for binding and fixing the additional steel bars to the cushion blocks, the positioning grooves can rapidly determine the positions in the placement process of the additional steel bars, the height of the cushion blocks effectively guarantees the interval between the additional steel bars and the profiled steel sheet, and the additional steel bars are prevented from being exposed after concrete is poured. After the additional steel bars are placed, the additional steel bars can be bound and fixed to the cushion block through the binding grooves in the cushion block, and therefore the technical problem that the additional steel bars of the profiled steel sheet are not easy to position is solved.

The present invention relates to a novel chimeric adapter protein and an extracellular vesicle containing the same, and more particularly, to a novel chimeric adapter protein and an extracellular vesicle containing the same, according to one aspect, the chimeric adapter protein can be abundantly expressed on the surface of the extracellular vesicle, has excellent binding efficiency, and does not interact with other components on the surface of the extracellular vesicle, thereby maintaining the integrity of the extracellular vesicle, etc. Good bioavailability and modularization are realized. When the medicine is loaded in the extracellular vesicles, the extracellular vesicles can also be used as an effective nano-carrier.

The embodiment of the invention discloses a meta-object code generation method and device, electronic equipment and a storage medium. According to the technical scheme, before the first source code file is compiled, the first source code file is pre-analyzed, the first connection statement in the source code is recognized, and the first connection statement is used for connecting the first function and the second function; obtaining a corresponding first function index and a second function index based on the first connection statement, and generating index mapping information based on the first function index and the second function index; and in the process of compiling the first source code file, generating a meta-object code corresponding to the first connection statement based on the index mapping information. By means of the technical means, the code size can be effectively controlled while the function binding efficiency is improved, and the dual requirements for program efficiency and size in the resource-constrained environment are met.

This invention discloses an anti-Dabie Banda virus Gn protein nanobody, a bispecific antibody, and their applications, belonging to the field of biodetection technology. This invention constructs an alpaca natural nanobody library, using recombinantly expressed Gn protein as the antigen. Through multiple rounds of gradient screening using phage display technology, three nanobodies—G15, G20, and G40—that specifically bind to the Dabie Banda virus Gn protein are obtained. All three antibodies exhibit excellent antigen-binding specificity and virus-neutralizing activity; among them, G40 shows the most prominent neutralizing effect. The bispecific antibody G40-C1q, constructed based on G40, combines Gn protein and human C1q protein, achieving a synergistic effect of antiviral activity and inhibition of inflammatory damage. It can be used for the development of drugs for the prevention and treatment of Dabie Banda virus infection and for high-specificity detection reagents, providing candidate antibody drugs for the treatment of fever with thrombocytopenia syndrome, and providing a reliable tool for virus-related research, disease diagnosis, and clinical translation.

The utility model relates to the technical field of reinforcing steel bar binding machines, and discloses efficient reinforcing steel bar binding tool equipment which comprises an operating handle, a rotating motor is fixedly installed on the inner wall of the operating handle, a fixed outer cylinder is fixedly installed on a power output shaft of the rotating motor, and a sliding inner cylinder is connected to the inner wall of the fixed outer cylinder in a sliding mode. A movable groove is formed in the outer edge of the fixed outer barrel, first clamping grooves are formed in the two sides of the inner wall of the movable groove, a movable block is slidably connected to the inner wall of the movable groove, and square grooves are formed in the two sides of the movable block. Through cooperative use of a first clamping block and a first clamping groove, when the length of a binding operation head needs to be extended, and then a steel bar in the distance can be bound conveniently, only first pressing blocks on the two sides of a movable block need to be pressed inwards, so that the first pressing blocks drive a movable plate to contract backwards on the inner wall of a square groove and extrude a first spring to deform and contract, and then the steel bar in the distance can be bound conveniently; and when the outer side of the pressing block I is flush with the outer side of the movable block.

The present application relates to the field of steel binding, especially a synchronous movement mechanism and control method for a steel binding robot, comprising a box, the inside of the box is provided with a binding gun, the present application has easy to assemble and disassemble, easy to carry, easy to maintain compared with the traditional binding mode: modular assembly unit, assembly type fastener connection, only need to adjust the tightness of the fastener, ensure the synchronous wheel rotation smooth, for the easy-to-damage parts such as synchronous belt, the present application can be quickly disassembled, easy to turnover, and the weight is smaller; The stroke reaches millimeter level: while ensuring the lightweight structure, the moving precision of XY movement and Z axis lifting reaches millimeter level; Safe and reliable: after being assembled into an integral template, the synchronous movement mechanism is used to position the steel binding point, automatic operation is realized, traditional manual binding is reduced, binding efficiency is improved, manual on-site assembly and disassembly work is reduced, and safety accidents caused by long-time fatigue operation of handheld electric tools are avoided.

This invention discloses a method for co-flotation recovery of clean coal from coal gasification fine slag and waste plastics, comprising the following steps: 1) mixing waste plastic particles, coal gasification fine slag, and water, adding a modifying agent, and grinding to obtain a grinding product; 2) filtering the grinding product, and then stacking the filter cake for settling to obtain a settling product; 3) flotating the settling product to separate low-ash clean coal and high-ash tailings. This invention, through precise control of grinding mixing and settling modification, combined with the modifying and strengthening effect of maleic anhydride-grafted polyethylene wax, significantly improves the hydrophobicity of the residual carbon surface, resulting in clean coal with lower ash content and higher calorific value. It can be directly used for coal blending, coal briquette preparation, or as a raw material for coal chemical industry, greatly increasing added value. The tailings, after treatment, can be used as building materials without secondary pollution, forming a closed-loop system of "solid waste treatment - resource output - end-use application," suitable for large-scale industrial promotion.

The invention relates to a waveguide correction lens manufacturing method and intelligent glasses, and the method comprises the steps: providing a correction lens and a waveguide sheet, arranging a cylindrical convex part on the binding surface of the correction lens, arranging a first barb on the peripheral region of the cylindrical convex part, arranging a cylindrical concave part complementary with the cylindrical convex part on the binding surface of the waveguide sheet, and arranging a second barb on the binding surface of the waveguide sheet; second barbs are arranged in the circumferential area of the inner wall of the columnar concave part; the waveguide sheet and the correction lens are arranged in an aligned manner, pre-pressure is applied, and the columnar convex part and the columnar concave part form positioning abutting; the double-laser heat source is started and focused on the columnar convex part and the columnar concave part respectively, the columnar convex part and the columnar concave part are guided to generate elastic deformation through photo-thermal treatment, and the columnar convex part is slowly embedded into the columnar concave part; and after cooling, the columnar convex part and the columnar concave part are elastically deformed to restore the original shape, and the first barb and the second barb are mutually buckled to form a mechanical interlocking structure for limiting relative displacement, so that the reliability of structural connection can be ensured without an adhesive, the bonding efficiency is high, and the yield is high.

The present application relates to a kind of transformer core column automatic binding shaping device, it is related to transformer technical field.The automatic binding machine main body is installed with lifting column in the rear side of the automatic binding machine main body, lifting frame is connected with the sliding block position of lifting column, hollow turntable is installed in the bottom of lifting frame, bottom plate is connected with the bottom of hollow turntable, and winding disc is rotatably connected with the bottom of bottom plate.The present application, by starting motor drives screw rod to rotate, screw rod rotation drives sliding plate movement, sliding plate movement drives cutter plate and core column to be attached, and cutter plate will be vertically moved during the process of attachment to make rubber band enter to the cutting edge position of cutter plate and cut, it is convenient and fast, and lifting frame inside is equipped with identification inductor, and rubber band that surface has been coated with reaction material can be automatically surface, and then more efficiently gradually on the surface of core column winding rubber band can be disassembled, improve the binding efficiency of core column glass fiber band.

The application provides a Bst DNA polymerase domain, a mutant and application thereof, and belongs to the technical field of molecular biology. The amino acid sequence of the Bst DNA polymerase domain is shown in SEQ ID NO:1. The Bst DNA polymerase mutant is obtained by replacing the natural DNA binding domain of the wild-type Bst DNA polymerase with the amino acid sequence shown in SEQ ID NO:1. The Bst DNA polymerase mutant exhibits extremely high catalytic efficiency on dUTP, and also has excellent hot-start characteristics, and can reduce the false positive rate of LAMP technology to close to zero. The Bst DNA polymerase mutant also has extremely strong complex sample tolerance, and the detection sensitivity of the pathogen is 20 times higher than that of the wild-type Bst enzyme, and can meet the early and accurate diagnosis requirements of trace infection.

The utility model discloses a multifunctional steel bar binding tool, and particularly relates to the field of building construction, including handle shell, the inside of handle shell is provided with the accommodation groove, and the one end portion inside of handle shell is connected with the lengthened adjustable handle, and the other end portion inside of handle shell is connected with the hook handle, and the inside of accommodation groove is connected with the cutting handle above the hook handle, and the one end top of cutting handle is provided with the gear extending to the outside of handle shell, and the outside of gear is connected with the handle, and the first connecting shaft is connected between the lengthened adjustable handle and the end portion of handle shell, and the end portion inner wall of handle shell is connected with the second connecting shaft, and the one end portion of second connecting shaft passes through hook handle, cutting handle and is connected to the middle part of gear.

The utility model discloses a spiral loose-leaf loading and metering mechanism which is used for arranging a spiral ring in a mounting hole of a loose-leaf in a penetrating mode, the spiral ring is a hollow cylindrical main body with two open ends, the top end and the tail end of the spiral ring are both provided with notches, the tail end of the spiral ring extends out of two opposite positioning extending bodies on the two sides of the notches, and the positioning extending bodies are arranged on the two sides of the notches. Comprising a ring penetrating core shaft, and the spiral ring is axially arranged on the ring penetrating core shaft in a penetrating mode; the surface of the rolling wheel abuts against the outer wall of the spiral ring, static friction is formed between the rolling wheel and the outer wall of the spiral ring, and the spiral ring is driven to rotate through rotation, so that the spiral ring is wound into the mounting hole of the hinge; and the setting needle group comprises a movable contact pin I, a movable contact pin II and a movable contact pin III. According to the spiral ring binding device, automatic binding of spiral rings is achieved, labor cost is saved, and binding efficiency is improved.

This application relates to the field of Internet of Things (IoT) technology and provides a control device, control method, equipment, medium, and product for clothing processing equipment. The control device includes: a first receiving module, configured to receive a first query request sent by a mobile terminal, the first query request being used to request identification information of at least one bindable device corresponding to the first clothing processing equipment; and to receive a device combination instruction sent by the mobile terminal, the target device being one of the at least one bindable device; a first processing module, configured to, upon detecting the first query request, obtain a list of bindable devices corresponding to the first clothing processing equipment and send the list of bindable devices to the mobile terminal, the list of bindable devices including identification information corresponding to at least one bindable device; and, upon detecting the device combination instruction, bind the target device to the first clothing processing equipment. This can improve the binding efficiency between a washing machine and a dryer.

The application belongs to the technical field of textile material preparation, and provides a siro compact textile with shape memory macromolecule and a preparation method thereof. Shape memory polyurethane filaments are prepared first, then A roving is prepared from combed cotton short fibers and low-melting-point sheath-core polyester short fibers, B roving is prepared from combed cotton short fibers, and the shape memory polyurethane filaments are introduced into the A roving to form an active strand, thereby obtaining eccentric active siro compact yarn; then the eccentric active siro compact yarn is woven with ordinary siro compact yarn in a partitioned manner to form a fabric base cloth, arc surface heat setting treatment is performed, and hot pressing is combined to form a hot anchoring point, so that the obtained fabric can be locally structurally recovered after being heated under pressure, and the obtained fabric has both the structural stability of siro compact yarn and the shape memory response characteristics, and is suitable for functional textiles with local support recovery requirements.

Provided is a waveguide element that can be connected to another waveguide member with excellent bonding efficiency. A waveguide element (100) according to an embodiment of the present invention is provided with a waveguide (1), a low refractive index layer (2), and a support substrate (3). The waveguide (1) is made of an optical functional material. The waveguide (1) is implanted in the low refractive index layer (2). The low refractive index layer (2) has a first cladding portion (21). The first cladding portion (21) is located on the opposite side from the support substrate (3) with respect to the waveguide (1) in the thickness direction of the low refractive index layer (2). The waveguide (1) has a first end section (11) and a second end section (12) in the thickness direction of the low refractive index layer (2). The width (W1) of the first end section (11) is equal to or less than the width (W2) of the second end section (12), and is 0.60-1.00 with respect to the width (W2) of the second end section (12). The width (W1) of the first end portion (11) is 0.80-1.30 with respect to the thickness dimension (Tg) of the waveguide (1). The thickness (T1) of the first cladding portion (21) is 0.30 or more with respect to the height (Tg) of the waveguide (1).

The invention discloses an antibody and a kit for detecting citrinin in traditional Chinese medicine and application of the antibody and the kit. The rapid and accurate pretreatment method based on immunomagnetic bead design is developed, the screened citrinin antibody coupling immunomagnetic beads are applied to the method, and compared with the prior art, the operation is faster, automation is easy to achieve, the combination efficiency is high, the applicability is wide, the subsequent detection result is more accurate, and the method is suitable for large-scale popularization and application. The method is especially suitable for a traditional Chinese medicine complex matrix and an automatic high-throughput detection platform, facilitates rapid screening of citrinin in traditional Chinese medicinal materials, and can provide a simple and convenient supervision means for fungaltoxin in the traditional Chinese medicinal materials.

This utility model proposes a rebar positioning correction structure, belonging to the technical field of construction equipment. By setting up a horizontal pressure plate, a vertical pressure plate, a first mounting hole, a second mounting hole, an electric cylinder, and a guide telescopic rod, the inner wall contours of the first mounting hole of the horizontal pressure plate and the second mounting hole of the vertical pressure plate are wedge-shaped. This allows for the initial positioning and orientation adjustment of the cross-laid rebars to be corrected, ensuring the stability of the rebar laying and avoiding subsequent tying difficulties caused by rebar position deviations. It also reduces the time and labor costs of repeatedly adjusting the rebar position, significantly improving the efficiency of rebar tying and installation. The electric cylinder raises and lowers the horizontal and vertical pressure plates. When the rebar is unevenly laid, it can clamp the beginning and end of the rebar, adjusting the gap between the horizontal and vertical rebars. This adjustable design greatly enhances the structure's adaptability to different construction conditions and complex working conditions, ensuring high precision and high quality in rebar installation.

The invention discloses a moisturizing mask and a preparation method thereof, and relates to the technical field of masks, the mask comprises a mask matrix and essence; the essence is prepared from the following raw materials in parts by weight: 80-90 parts of water, 4-6 parts of butanediol, 1-3 parts of 1, 3-butanediol and 1-3 parts of 1, 3- The cosmetic is prepared from the following raw materials in parts by weight: 1 to 5 parts of 1, 3-propylene glycol, 1 to 2 parts of betaine, 0.5 to 1.5 parts of glycerol, 1 to 3 parts of glyceryl polyether-26, 0.1 to 1 part of p-hydroxyacetophenone, 0.1 to 0.5 part of saccharide isomeride, 0.1 to 0.5 part of carbomer sodium, 0.1 to 0.5 part of dendrobium huoshanense stem extract, 0.1 to 0.3 part of cottonrose hibiscus leaf extract, 0.1 to 0.3 part of tamarind seed fermentation extract, 0.01 to 0.05 part of sodium hyaluronate, 0.001 to 0.01 part of oligopeptide-1, 0.001 to 0.005 part of citric acid and 0.001 to 0.005 part of sodium citrate. And 0.0001 to 0.001 part of acetyl hexapeptide-8. The moisturizing performance of the mask is remarkably improved.

The application provides an acylated aldehyde dehydrogenase AldDH mutant and application thereof in production of 6-aminohexanoic acid. Specifically, the acylated aldehyde dehydrogenase AldDH mutant comprises a mutation based on a reference sequence, the reference sequence is shown as SEQ ID NO:1, and the acylated aldehyde dehydrogenase AldDH mutant comprises an amino acid mutation corresponding to at least one of positions A67, C69, N71, S75, W78, R86, I118, F238, L243, T245, W350, G399, T400, N401, A405 and T414 of SEQ ID NO:1. The 6-aminohexanoic acid production strain constructed by using the acylated aldehyde dehydrogenase AldDH mutant of the application can efficiently synthesize 6-aminohexanoic acid from glucose.

The invention relates to the technical field of biomedicine nanotechnologies, and discloses degreasing nanoparticles simulating a high-density lipoprotein structure and a preparation method thereof.The nanoparticles are formed by assembling human recombinant apolipoprotein A-I and 1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphorylcholine according to the molar ratio of 90: 1-120: 1. The method comprises the following steps: incubating apolipoprotein in a polyethylene glycol molecule crowded environment to induce dominant conformation; constructing a phospholipid-supercritical carbon dioxide system, pumping protein liquid, and realizing instant self-assembly by utilizing a synergistic effect of ultrasonic cavitation and rapid pressure relief expansion; and finally, carrying out tangential flow ultrafiltration purification through a polyethersulfone membrane subjected to surface grafting hydrophilic modification. According to the process, protein aggregation and inactivation are effectively avoided, the problem of membrane pollution is solved, and the assembly efficiency, the particle size uniformity, the degreasing biological activity and the product yield of the nanoparticles are improved.