15 results about "Isothiocyanate" patented technology

A novel bis-ligand chalcopyrite collector and a preparation method and application thereof. The collector is prepared by first synthesizing an intermediate oxalyl diisothiocyanate from oxalyl chloride and thiocyanate, and then reacting the intermediate with an amine or an alcohol using a one-pot method. The collector provided by the present disclosure can form more stable dual-site adsorption on the chalcopyrite surface, thereby generating a more stable double-chelate-ring structure than the single-site adsorption of a traditional chalcopyrite collector such as xanthate and dithiophosphate. The collector not only has higher collection ability and excellent selectivity, but also can achieve efficient copper-sulfur separation even under a low-alkalinity condition. The preparation process of the collector is simple and operable, facilitating the flotation of chalcopyrite and its separation from pyrite.

Compositions and methods are disclosed for improving seed quality. For example, treating a stand of seed crops with a seed crop treatment that includes an effective amount of cyanate, thiocyanate, an acceptable salt of cyanate or thiocyanate, an ester of cyanate or thiocyanate, an isocyanate or isothiocyanate, or a combination thereof results in one or more improved seed qualities compared to a control. The improved seed qualities may include, but are not limited to, enhanced seed vigor, increased quantity of saleable seed, increased proportion of saleable seed, increased uniformity of seed shape and size, and desirable bag weight.

The present invention relates to a method for separating and / or isolating exosomes from a sample, the method comprising the steps of i) providing a sample that is known to comprise or suspected of comprising exosomes; ii) contacting a first binding agent with the sample and allowing the binding agent to bind to exosomes, wherein the first binding agent comprises a) cinnamycin and fluoresceine isothiocyanate (FITC), wherein the FITC is covalently linked to cinnamycin, or b) a protein-tag linked to cinnamycin via a peptide linker, wherein the peptide linker comprises one or more proteolytic cleavage sites; iii) separating and / or isolating complexes of the first binding agent and exosomes from the sample. The present invention further relates to a binding agent to be used in the method and to kits comprising the binding agent and instructions for binding of said binding agent to exosomes in a sample.

The application belongs to the technical field of medicine preparation, and specifically discloses an interfering peptide for inhibiting mitochondrial autophagy induced by a coronavirus nucleocapsid protein, and a preparation method and application thereof. The interfering peptide (named ISQORbeta2) is composed of D-type amino acids, and the structure comprises: a polypeptide sequence as shown in SEQ ID NO:1; and 5-isothiocyanate fluorescein covalently connected to the N terminal of the polypeptide. The interfering peptide effectively inhibits mitochondrial autophagy activation, intracellular H2S accumulation, mitochondrial potential depolarization, and restores the expression of innate immune molecules by competitively blocking the interaction between IBV-N and SARS-CoV-2-N and sulfide quinone oxidoreductase, thereby resisting viral replication and reducing lung injury. The application solves the problems of the prior art, such as difficulty in blocking protein interaction, poor peptide stability, and inability to effectively restore the immune pathway, and has the advantages of high in-vitro and in-vivo stability, small toxic and side effects, and great potential for drug development.

This invention belongs to the field of battery technology, and particularly relates to a lithium-ion battery. Compared with the prior art, this invention comprehensively controls the content of isothiocyanate additives in the electrolyte, the porosity and adhesion of the negative electrode active layer in the negative electrode sheet, thereby reducing the interfacial impedance between the negative electrode sheet and the electrolyte while avoiding separation of the negative electrode active material layer and the current collector, and improving the lithium-ion transport rate, thus enhancing the overall kinetic performance.

The present application relates to the technical field of organic synthesis, in particular to a kind of 3-thio / seleno phosphorylated imidazole derivatives and synthesis method and application thereof, the structure general formula of the 3-thio / seleno phosphorylated imidazole derivative is, R 1 Be aryl or alkyl, X is sulfur element or selenium element, R 2 Be methyl or ethyl etc., R 3 Be ethyl or n-butyl etc.;The synthesis method is to use isothiocyanic acid ester or isoselenocyanate, isocyanate and phosphite as reaction raw material, synthesis by electrochemical oxidation reaction.The synthesis method provided by the present application adopts in the integrated cell without metal and chemical oxidant, constructs 3-thio / seleno phosphorylated imidazole derivative by one-pot three-component cross coupling cyclization, has the advantages of simple operation, raw material is cheap and easy to obtain, high synthesis efficiency, high atom economy, is conducive to large-scale preparation and production;3-thio / seleno phosphorylated imidazole derivative disclosed by the present application has excellent locust control activity and protective effect on wheat seedlings, and does not affect aquatic environment at low concentration, and has good biocompatibility, and can be used for preparing biological pesticide.

The present application relates to allyl covalent organic framework material and its application in isothiocyanate-aromatic amine cyclization reaction. The D-COF material is prepared by a step-by-step synthesis path: first, using triformylphloroglucinol and p-aminophenylacetonitrile as reaction monomers, a covalent organic framework precursor is prepared; then the precursor is synthesized with benzo[1,2-b:3,4-b':5,6-b']trithiophene-2,5,8-trialdehyde by solvothermal method, and the material is applied as a photocatalyst in 1-isothiocyanonaphthalene dehydrogenative coupling reaction. Under the condition of blue light LED irradiation, efficient catalytic conversion of 1-isothiocyanonaphthalene dehydrogenative coupling reaction can be realized. The D-COF catalyst has excellent photo-induced charge separation efficiency and electron transport characteristics, and at the same time, it has stable structure and good chemical resistance; its photocatalytic reaction system has the advantages of wide substrate application range, and the catalyst can be recycled, etc., showing excellent catalytic application potential in the field of organic photocatalytic conversion.

An embodiment of the present invention addresses the problem of providing a compound capable of providing a liquid crystal composition excellent in characteristics such as Tni, Δn, Δεr, tanδiso and / or preserving properties, and providing a liquid crystal composition, a liquid crystal display element, a sensor, a liquid crystal lens, an optical communication device and an antenna each comprising the compound. The present invention addresses the problem of providing a compound capable of providing a liquid crystal composition having, for example, a high Tni, a large Δn, a large Δεr, and a small tanδiso and having satisfactory preserving properties at room temperature and providing a liquid crystal composition, a liquid crystal display element, a sensor, a liquid crystal lens, an optical communication device and an antenna each comprising the compound.　Specifically, the liquid crystal composition contains one or two or more compounds represented by general formula (i) having a predetermined ring structure and an isothiocyanate group (-NCS).