249 results about "Isothiocyanate" patented technology

The invention discloses a myrosinase-producing Cupriavidus strain and application of the myrosinase-producing Cupriavidus strain in prevention and treatment of soil-borne diseases. The preservation number of the Cupriavidus sp. Strain is CGMCC (China General Microbiological Culture Collection Center) NO.34736. The Cupriavidus sp. Strain is a Cupriavidus sp. Strain. The invention further provides application of the strain in prevention and treatment of soil-borne fungal diseases and a soil disinfection method. According to the soil disinfection method provided by the invention, the amount of isothiocyanate substances generated in a biological fumigation technology is greatly increased, and a remarkable inhibition effect on soil-borne pathogens can be achieved.

The invention relates to a method for producing microparticles comprising at least one organic active compound encapsulated by a shell of an organic wall material, the method comprising i. Providing a water-immiscible liquid containing the organic active compound to be encapsulated and at least one first shell-forming compound (SFC1); ii. Emulsifying the water-immiscible liquid obtained in step i. In an aqueous medium to obtain an oil-in-water (o / w) emulsion of the water-immiscible liquid in the aqueous medium; iii. Adding at least one second shell-forming compound (SFC2) to the aqueous medium or to the emulsion obtained in step ii. Prior to or during performing step ii., thereby obtaining an aqueous suspension of the microparticles; wherein the first shell-forming compound (SFC1) or the second shell-forming compound (SFC2) has 1, 2, 3, 4, 5 or 6, in particular 1, 2, 3 or 4, in particular 1, 2 or 3 first reactive groups (RG1) selected from isocyanate groups, isothiocyanate groups, carbonyl halide groups and carboxylic anhydride groups, per molecule, and the other shell-forming compound has 1, 2, 3, 4, 5 or 6, in particular 1, 2, 3 or 4, per molecule, in particular 1, 2 or 3 second reactive groups (RG2) selected from the group consisting of hydroxyl, thiol and primary amino groups, the first shell-forming compound (SFC1) or the second shell-forming compound (SFC2) having only one reactive group and the other shell-forming compound having 1, 2, 3, 4, 5 or 6, in particular 1, 2, 3 or 4, in particular 1, 2 or 3 reactive groups. The invention also relates to microparticles obtainable by this process and to the use thereof.

The invention belongs to the field of temperature control, and particularly relates to a reaction kettle temperature control method and system for synthesizing isothiocyanate. The method comprises the following steps: acquiring temperature, material concentration and coolant flow in a kettle in real time, calculating a reaction rate estimated value through a nonlinear mixed model, and calculating an active factor by combining catalyst input time and an index inactivation function; performing unequal weight combination on the three parameters to generate a scheduling variable, and calculating a current value and a second-order difference value of the scheduling variable; selecting a reference state space model according to the current value of the scheduling variable, and correcting the matrix by using a second-order difference value to obtain an LPV model; constructing a quadratic programming optimization problem, wherein an objective function comprises a temperature tracking error penalty term and a control input increment penalty term for adjusting the weight; when the temperature deviation exceeds the threshold value continuously, a control input value penalty term is added; and solving an optimization problem and outputting a first element of the control sequence to a temperature control execution mechanism. According to the invention, the temperature control precision and stability of the isothiocyanate synthesis reaction kettle are improved.

The invention relates to a thiourea-based aromatic porous organic polymer as well as a preparation method and application thereof, and belongs to the technical field of functional polymer adsorption materials. The preparation method comprises the following steps: respectively dissolving a plurality of ternary aromatic amine monomers with different electron pushing (electron donating) effects and cheap binary isothiocyanate monomers, mixing, uniformly shaking, and reacting to obtain a porous organic polymer network which is shown as organogel; and grinding the organogel into powder, then carrying out solvent exchange in dichloromethane, treating in methanol by using a Soxhlet extractor, and finally drying to obtain the product. The thiourea-based aromatic porous organic polymer provided by the invention has good adsorptive selectivity to Au, high adsorption capacity, wide pH adaptation range, good cyclic adsorption performance, simple preparation method and relatively high practical application value.

The invention provides a self-repairing material containing a dynamic hindered thiourea bond as well as a preparation method and application of the self-repairing material. The self-repairing material containing the dynamic hindered thiourea bond is prepared from the following raw materials: polydimethylsiloxane, a diisothiocyanate compound, anhydrous piperazine and an optional amine cross-linking agent. The molar ratio of the four components is (3-4): 6: 2: (0-0.7); wherein the two ends of the polydimethylsiloxane are terminated by amino alkyl. A self-repairing material formed by polydimethylsiloxane, a diisothiocyanate monomer, anhydrous piperazine and an optional amine cross-linking agent according to a specific molar ratio is adopted, and a dynamic hindered thiourea bond is introduced into a polymer material, so that the self-repairing material is endowed with repairing capacity under the condition that the insulating property of the self-repairing material is not sacrificed; the self-repairing material not only has good insulating property and mechanical property, but also has excellent self-repairing property.

The invention relates to the technical field of preparation of polyurethane plastic materials, in particular to an environment-friendly high-elasticity foaming material as well as a preparation method and application thereof. The preparation method of the foaming material comprises the following steps: perfluorooctyl sulfonyl fluoride and diaminopropyl polydimethylsiloxane are subjected to a reaction, and fluorine-containing polydimethylsiloxane is obtained; the preparation method comprises the following steps: reacting 3-(3, 5-di-tert-butyl-4-hydroxyphenyl) propanohydrazide with terephthalic diisothiocyanate to obtain isothiocyanate modified hindered phenol; the isothiocyanate modified hindered phenol reacts with primary amine at the terminal position of a fluorine-containing polydimethylsiloxane molecule through an isothiocyanate group to obtain an intermediate, and the intermediate is subjected to a desulfurization reaction to obtain a modifier; the preparation method comprises the following steps: reacting diisocyanate with polyether polyol, polyester polyol and natural polyol to obtain a component A, and stirring and mixing polyether polyol, a bio-based chain extender, a modifier, a catalyst and a foaming agent to obtain a component B; stirring and mixing the component A and the component B, and foaming to obtain the environment-friendly high-elasticity foaming material.

Provided is a composition which contains a base generator and a polymerizable compound. The base generator contains a salt of a cation and an anion. The cation contains a carbonyl group and a partial structure comprising: a carbon atom; a nitrogen atom N1 bonded via a single bond to the carbon atom; and a nitrogen atom N2 bonded via a double bond to the carbon atom. The polymerizable compound contains a polyiso(thio)cyanate compound and a polythiol compound.

The invention belongs to the technical field of copper-sulfur ore flotation, and particularly relates to a novel double-ligand chalcopyrite collecting agent and a preparation method and application thereof. According to the collecting agent, an intermediate oxalyl diisothiocyanate is mainly prepared from oxalyl chloride and thiocyanate through a thiocyanate method, and then series amine / alcohol is added through a one-pot method to prepare the collecting agent. According to the collecting agent, more stable double-bond adsorption can be formed on the surface of chalcopyrite, and the formed double-chelate ring structure is more stable than single-bond adsorption of xanthate, black powder and the like of a traditional chalcopyrite collecting agent. The collecting agent has higher collecting capacity and excellent selectivity, efficient copper-sulfur separation can be achieved under the low-alkali condition, the preparation technology of the collecting agent has the advantages of being simple, easy to operate and the like, and chalcopyrite flotation and separation of chalcopyrite and pyrite can be promoted.

The invention provides a planting method for promoting high yield of eggplants, and relates to the technical field of vegetable planting. The planting method mainly comprises the steps that a base fertilizer is applied to a planting field for ridging treatment, eggplant seedlings are sprayed with a treating agent for seedling hardening treatment, the eggplant seedlings are planted, a nutritional agent is used as a liquid fertilizer and a leaf fertilizer, and the treating agent is prepared from water-soluble calcium carbonate, ammonium dihydrogen phosphate, anthocyanin and a bacillus tequilensis fermentation extracting solution. The nutritional agent is prepared by mixing a bacillus tequilensis fermentation extracting solution, ethyl isothiocyanate, a calcium-magnesium-boron-zinc-iron liquid fertilizer and germacrone. The method overcomes the defects in the prior art, effectively promotes eggplant planting and growth, promotes early fruiting and early harvesting of eggplants, comprehensively improves the yield of eggplants, and improves the economic benefits of planting.

The invention belongs to the technical field of preparation of organic compounds, and particularly relates to a preparation method of an isothiocyanate compound. According to the method, the myrosinase is fixed by using the metal organic framework, and column extraction is combined, so that the high-purity isothiocyanate compound can be obtained at high yield, the yield of the isothiocyanate compound is 90% or above, the purity is 97% or above, and the preparation efficiency is high. Compared with a traditional extraction method, the method has the advantages that immobilized myrosinase reaction and column extraction are coupled in real time, a solvent is saved, meanwhile, the product isothiocyanate compound is transferred into an organic phase in time, decomposition of the isothiocyanate compound and potential inhibition of the isothiocyanate compound on the activity of myrosinase are avoided, and the method is suitable for industrial production. The isothiocyanate compound is efficiently enriched, so that the purity and the yield of the isothiocyanate compound are improved.

The invention discloses an acylthiourea compound as well as a preparation method and application thereof. The preparation method comprises the following steps: firstly, preparing an acyl isothiocyanate intermediate from caffeic acid serving as a raw material, protecting hydroxyl on a benzene ring of the raw material by using TBS, then reacting with primary amine to prepare an acylthiourea intermediate, and finally, removing the TBS protective agent under the action of TBAF, thereby obtaining the acylthiourea compound. Experiments show that the acylthiourea compound has a medicinal value, can be used for treating inflammatory bowel diseases, and can be applied to development of related drugs.

The invention relates to the technical field of polypropylene nucleating agents, and particularly discloses a polypropylene beta nucleating agent based on polythiourea and a preparation method and application thereof.The preparation method comprises the steps that under the nitrogen protection atmosphere, 1, 4-phenyl diisothiocyanate and an amino-terminated compound are added into a solvent, and a constant-temperature stirring reaction is conducted; after the reaction is completed, a reaction product is subjected to precipitation, filtration, impurity removal and drying, and a precipitate is obtained; and dissolving the precipitate in a solvent, forming a film, and then grinding or cutting into pieces to obtain the polypropylene beta nucleating agent. The polypropylene beta nucleating agent based on polythiourea prepared by the invention is a novel polypropylene beta nucleating agent containing a thiourea group, has unique hydrogen bond network and pi-pi accumulation effect, and can induce polypropylene to form a beta crystal form in a wide temperature range after polypropylene is melt-blended; the mechanical property and the electric breakdown resistance of the polypropylene material are improved. The preparation method is simple, low in production cost and suitable for large-scale industrial application.

The purpose of the present invention is to provide: a curable composition that makes it possible to provide a cured body exhibiting excellent adhesion to a substrate; a cured body thereof; and a laminate, an optical article, a lens, and spectacles that include said cured body. One embodiment of the present invention provides a curable composition. The curable composition contains a first monomer and at least one of a second monomer and an organosilicon compound. The first monomer has an allyl group. The second monomer has a polymerizable group and a first functional group. The polymerizable group is at least one type of group selected from the group consisting of an acryloyl group, a methacryloyl group, and a vinyl group. The first functional group is at least one type of group selected from the group consisting of an isocyanate group, an isothiocyanate group, an epoxy group, and an aldehyde group. The organosilicon compound has a second functional group and a hydrolyzable group.

The invention provides a preparation method of a cholestatic liver injury animal model, which comprises the following steps: on the basis that a mouse is fed with a feed containing 500IU / kg vitamin A for 8 weeks to cause deficiency of vitamin A in the mouse body, performing intragastric administration of alpha-naphthyl isothiocyanate (ANIT) at 50mg / kg for 4 weeks once a week, so as to obtain the cholestatic liver injury mouse model. The blood biochemical index ALT, the liver index, the pathological structure change of the liver tissue and the bile acid deposition of the liver tissue are more obvious. The cholestatic liver injury model prepared by the preparation method can avoid the influence of inconsistent dosage and unstable model in a conventional method, and can be applied to the research fields of molecular mechanism research of occurrence and development of cholestatic liver injury, finding of cholestatic liver injury treatment medicines and methods and the like.

The invention provides a preparation method of a novel chiral thiourea / phosphine bifunctional organic catalyst with a cis-cyclic 1, 2-phosphinamine skeleton and application of the novel chiral thiourea / phosphine bifunctional organic catalyst in an asymmetric catalytic reaction. The chiral organic catalyst is prepared by taking cis chiral 2-(diphenylphosphine)-1, 2, 3, 4-tetrahydro-1-naphthylamine and an isothiocyanate compound as raw materials through a one-step reaction under a mild condition. The chiral thiourea / phosphine bifunctional organic catalyst is simple to prepare and stable in property, and shows excellent catalytic activity and stereoselectivity in an asymmetric hydrosilylation reaction of o-amido benzophenone.

The present application belongs to the technical field of protein composition, and relates to a collagen composition and a preparation method thereof. The present application provides a preparation method of a collagen composition, which comprises the following steps: preparing a collagen solution by treating raw hide which has not been subjected to chemical cross-linking treatment; adding a cross-linking promoter, an isothiocyanate and alpha-mammeigin to the collagen solution; and finally obtaining the collagen composition by multiple short-time microwave treatment. The collagen composition provided by the present application avoids the use of a cross-linking agent, has the advantages of no cytotoxicity, high cross-linking degree and good stability, and exhibits excellent antibacterial and antioxidant functions.

The present invention discloses a pH- and thermoresponsive iron nanogel and its preparation method and application. The iron nanogel is composed of Fe3O4 nanoparticles surface-modified with compound 2, compound 3, RNA or protein, polyethyleneimine-polyethylene glycol, and dopamine. Compound 2 is a small molecule compound containing ortho-dihydroxybenzene groups and having a protected boronic acid group structure at the end. Compound 3 is a small molecule structure in which phenyl diisothiocyanate-modified glycine has an exposed carboxyl group at the end that can react with amino groups. The iron nanogel in the present invention not only has good magnetic thermal properties but also has the ability to encapsulate drugs. Under the condition that certain acid and heat coexist, the iron nanogel can be controllably disassembled to release bioactive drugs, activate the body's immune system, and inhibit the growth of tumor cells by means of mild hyperthermia to achieve the effect of combined therapy.

The present invention discloses a preparation method of thiazolidine-4-thione derivatives, which comprises the following steps: (1) mixing an isothiocyanate or its derivative, a sulfur ylide, an additive and an organic solvent, and reacting at 20-90 °C for 12-48 h under an air atmosphere; (2) diluting the material obtained in step (1) with ethyl acetate and washing with water, and separating to obtain an organic phase; (3) subjecting the above organic phase to drying, filtration, concentration and column chromatography or thin-layer chromatography in sequence to obtain thiazolidine-4-thione derivatives. The present invention can construct tetra-substituted thiazolidine-4-thione derivatives, can efficiently synthesize thiazolidine-4-thione derivatives containing trifluoromethyl, the raw materials used are easily available, the yield is high, the reaction conditions are mild, the reaction time is short, the substrate range is wide, the reaction specificity is strong, and the post-treatment is simple.

The application discloses a tryptamine detection method based on triple emission MOFs and a smart phone. A rare earth metal organic framework (AP-Eu) is used as a luminescent matrix, and a fluorescent guest molecule fluorescein-5-isothiocyanate (FITC) is post-modified to obtain a ratio fluorescent material with triple emission characteristics. Competitive absorption of ligands and tryptamine, pH response of FITC and hydrogen bonding are used to realize fluorescence signal regulation, and then high-sensitivity and high-selectivity fluorescence recognition of tryptamine is realized. The method is further applied to quantitative detection of tryptamine in beer samples, visualization detection of foam and on-site rapid detection assisted by a mobile phone APP. The application provides a safe and efficient tryptamine detection and fluorescence sensing method, and significantly improves detection accuracy and on-site applicability.

The invention discloses a recoverable adhesive suitable for bonding of different base materials and a preparation method and application thereof, and relates to the technical field of adhesives. The recyclable adhesive is prepared from the following components in parts by weight: 20 to 40 parts of polyamine monomer, 3 to 8 parts of diisothiocyanate monomer and 3 to 8 parts of modified tannic acid. The preparation method comprises the following steps: preparing modified tannic acid; the preparation method comprises the following steps: mixing diisothiocyanate and a polyamine monomer to generate an isothiocyanate group terminated prepolymer; and mixing the modified tannic acid and the isothiocyanate-terminated prepolymer, and carrying out covalent crosslinking through a Michael addition reaction, so as to prepare the recoverable adhesive.

The invention belongs to the technical field of biosensing detection, and particularly discloses a label-free ratio fluorescence sensor and application thereof in quinine detection. The label-free ratio fluorescent aptamer sensor takes isothiocyanate as an internal reference signal and a fluorescent dye as a detection signal, and is obtained by mixing and incubating a quinine specific nucleic acid aptamer, a triphenylmethane fluorescent dye and isothiocyanate in a buffer solution. According to the invention, isothiocyanate is introduced as an internal reference signal, triphenylmethane dye is selected as a target response fluorescence signal molecule, and the quinine is detected by using the obvious fluorescence change of the target response fluorescence signal molecule in the binding-dissociation process of the target response fluorescence signal molecule and a quinine specific nucleic acid aptamer. The label-free ratio fluorescence sensor has excellent selectivity and stability, can be widely applied to the fields of food safety supervision, drug quality control, environmental water quality detection and the like, and is particularly suitable for rapid detection and emergency monitoring of quinine under the condition of limited resources.

The present application provides an organic compound, a mixture, a composition and an organic electronic device. The structure of the organic compound is shown in the general formula (1): #imgabs0# wherein: n1, n2, and n3 are integers from 1 to 3; each occurrence of R1, R2, and R3 is independently selected from H, D, a straight-chain alkyl group, a straight-chain alkoxy group, a straight-chain thioalkoxy group, a branched or cyclic alkyl group, a branched or cyclic alkoxy group, a branched or cyclic thioalkoxy group, a silyl group, a keto group, an alkoxycarbonyl group, an aryloxycarbonyl group, a substituted or unsubstituted aromatic group or heteroaromatic group, an aryloxy or heteroaryloxy group, a cyano group, a carbamoyl group, a halocarbonyl group, a formyl group, an isocyano group, an isocyanate group, a thiocyanate group, an isothiocyanate group, a hydroxyl group, a nitro group, an amino group, CF3, Cl, Br, F, I, or a combination of these groups. The organic compound provided by the present application can increase the luminous efficiency and service life of the organic electronic device.

A food with an extended shelf-life and a method of extending shelf-life of food is provided herein. The extended shelf-life is provided by treating the food with at least one shelf-life extender selected from a group consisting of an isothiocyanate, a non-aromatic cyclic ketone, a boronic acid, a ligand and their precursors.

A novel bis-ligand chalcopyrite collector and a preparation method and application thereof. The collector is prepared by first synthesizing an intermediate oxalyl diisothiocyanate from oxalyl chloride and thiocyanate, and then reacting the intermediate with an amine or an alcohol using a one-pot method. The collector provided by the present disclosure can form more stable dual-site adsorption on the chalcopyrite surface, thereby generating a more stable double-chelate-ring structure than the single-site adsorption of a traditional chalcopyrite collector such as xanthate and dithiophosphate. The collector not only has higher collection ability and excellent selectivity, but also can achieve efficient copper-sulfur separation even under a low-alkalinity condition. The preparation process of the collector is simple and operable, facilitating the flotation of chalcopyrite and its separation from pyrite.

This (meth)acrylate compound production method includes a step (A1) for generating a (meth)acrylate compound (a) that includes an allophanate bond by reacting an iso(thio)cyanate compound containing two or more iso(thio)cyanate groups and a (meth)acrylate compound (b) containing one or more hydroxy groups and one or more (meth)acryloyl groups in the presence of a zinc compound at a content ratio at which the contained molar ratio of the iso(thio)cyanate groups in the iso(thio)cyanate compound to the hydroxy groups in the (meth)acrylate compound (b) is greater than 1.

The present invention aims to provide a ni High, large Δn, V th Low, Δε r Large, tanδ iso Liquid crystal compositions that are small in size and have good storage properties at low temperatures, liquid crystal compositions, and liquid crystal display devices, sensors, liquid crystal lenses, optical communication devices, and antennas using the same. Specifically, the invention relates to a compound represented by the general formula (i) having an ethynylene group (-C≡C-) and an isothiocyanate group (-NCS), and a liquid crystal composition containing one or more such compounds.

This invention belongs to the field of rubber antioxidant technology, and specifically relates to an anti-caking composite rubber antioxidant 6PPD and its preparation method. The anti-caking composite rubber antioxidant 6PPD is prepared by reacting 3-aminoadipic acid with 4-pentenyl isothiocyanate, grafting it onto silica using a silane coupling agent, and complexing it with lanthanum ions to obtain a functional antioxidant. This functional antioxidant is then compounded with a base antioxidant N-(1,3-dimethylbutyl)-N'-phenyl-p-phenylenediamine, microcrystalline wax, and an antioxidant to prepare the anti-caking composite rubber antioxidant 6PPD. The prepared anti-caking composite rubber antioxidant 6PPD possesses multiple protective mechanisms—chemical protection, physical barrier, and multi-mechanism synergy—exhibiting excellent aging resistance, good processability, and easy storage due to its anti-caking properties.