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2966 results about "Vitamin" patented technology

A vitamin is an organic molecule (or related set of molecules) that is an essential micronutrient that an organism needs in small quantities for the proper functioning of its metabolism. Essential nutrients cannot be synthesized in the organism, either at all or not in sufficient quantities, and therefore must be obtained through the diet. Vitamin C can be synthesized by some species but not by others; it is not a vitamin in the first instance but is in the second. The term vitamin does not include the three other groups of essential nutrients: minerals, essential fatty acids, and essential amino acids. Most vitamins are not single molecules, but groups of related molecules called vitamers. For example, vitamin E consists of four tocopherols and four tocotrienols. The thirteen vitamins required by human metabolism are: vitamin A (as all-trans-retinol, all-trans-retinyl-esters, as well as all-trans-beta-carotene and other provitamin A carotenoids), vitamin B₁ (thiamine), vitamin B₂ (riboflavin), vitamin B₃ (niacin), vitamin B₅ (pantothenic acid), vitamin B₆ (pyridoxine), vitamin B₇ (biotin), vitamin B₉ (folic acid or folate), vitamin B₁₂ (cobalamins), vitamin C (ascorbic acid), vitamin D (calciferols), vitamin E (tocopherols and tocotrienols), and vitamin K (quinones).

Optical detection method and system for content of vitamin tablets

The invention relates to the technical field of medicine quality detection, and particularly discloses an optical detection method and system for the content of vitamin tablets. The method comprises the following steps: driving an optical fiber probe array to carry out three-dimensional multi-angle near-infrared scanning through a multi-axis mechanical arm, and collecting reflection spectrum data; a weighted spectrum is generated through derivative spectrum analysis and double evaluation, and auxiliary material noise is corrected and separated in combination with subspace projection and a dynamic kernel function; performing spectral vector projection and regression coefficient iterative optimization through an online PLS model, and synthesizing an error coefficient based on a four-level index retrieval standard library to perform dual-channel feedback; and finally, fusing the credibility weight to output a detection result of the binding confidence. The method realizes nondestructive and high-precision detection of the vitamin tablets, has the beneficial effects of multi-dimensional data fusion, dynamic error compensation and high model adaptability, and remarkably improves the detection accuracy and reliability.
Owner:CSPC ZHONGNUO PHARM (TAIZHOU) CO LTD

Multi-effect bionic liposome transdermal repair carrier as well as preparation and application thereof

The invention relates to a multi-effect bionic liposome transdermal repair carrier and a preparation method and application thereof.The multi-effect bionic liposome transdermal repair carrier comprises active ingredients and a nano-carrier, and the active ingredients comprise sialic acid, saccharomycetes / rice fermentation product filtrate, arginine / lysine polypeptide and vitamin E in the mass ratio of (1-10): (2-8): (0.1-1): (0.5-4); the nano-carrier is prepared from the following raw materials: phospholipid, an emulsifier, polyhydric alcohol and water. Compared with the prior art, the anti-aging, whitening and moisturizing composition has the advantages of enhancing skin moisturizing and anti-oxidation effects, promoting collagen synthesis and inhibiting tyrosinase to achieve remarkable anti-aging, whitening and moisturizing effects and the like.
Owner:MAGELINE BIOLOGY TECH CO LTD +1

Process and device for continuously synthesizing vitamin D3 through photocatalysis

The invention discloses a process and a device for continuously synthesizing vitamin D3 through photocatalysis, and relates to the technical field of process on-line monitoring and intelligent control. Photochemical reaction requirements under raw materials with different concentrations are matched through multi-band illumination weight dynamic distribution; when the concentration of the 7-dehydrocholesterol fluctuates, the illumination ratio of 290nm to 305nm wavebands is adjusted in real time by a reinforcement learning algorithm, so that the conversion of a pre-vitamin D3 intermediate is more efficient, and the competitive consumption of a by-product path is reduced; the reaction retention time is further optimized through synchronous flow rate adjustment, and local excessive irradiation caused by sudden concentration increase is avoided; the environment temperature and humidity change is incorporated into a state vector, and the control module generates a compensation instruction accordingly; and if the humidity changes suddenly, pulse type flow compensation is triggered to counteract reaction efficiency attenuation. A closed-loop response mechanism reduces the dependence on physical temperature control equipment, and is especially suitable for mobile production scenes.
Owner:ZHEJIANG BRILIS TECHNOLOGY CO LTD +1

Plant-source nutritional supplement based on glycoside compounds and preparation method of plant-source nutritional supplement

The invention discloses a plant-source nutritional supplement based on glycoside compounds and a preparation method thereof, and relates to the technical field of preparation of plant-source nutritional supplements.The preparation method comprises the steps that raw materials are prepared; the preparation method comprises the following steps: respectively carrying out ultrasonic-assisted extraction on flavonoid glycoside, saponin and geniposide raw materials to obtain an extracting solution; carrying out centrifugal separation on the extracting solution, taking supernate, and then purifying by adopting a macroporous resin adsorption method to obtain a purified glycoside compound solution; mixing the purified glycoside compound solution with lycium barbarum polysaccharide, Chinese yam starch, vitamin E and other auxiliaries in proportion, and uniformly stirring to form a mixed solution; carrying out spray drying on the mixed solution to obtain a powdery nutritional supplement; and screening the powdery nutritional supplement. The high-purity plant source glycoside compound and the functional auxiliary agent are scientifically compounded, and ultrasonic extraction, resin purification and precise process control are combined, so that the integrated improvement of activity synergy, quality stability and personalized scene adaptation of the nutritional supplement is realized.
Owner:HUBEI BOHAI BIO-HOLDING GROUP CO LTD

Vitamin E-rich linseed oil for enhancing linolenic acid activity and preparation method thereof

The invention provides linseed oil rich in vitamin E and capable of enhancing linolenic acid activity and a preparation method of the linseed oil, and belongs to the technical field of edible oil processing. The preparation method of the flaxseed oil comprises the following steps: mechanically polishing and degumming flaxseeds, and then carrying out microwave thermal refining and low-temperature squeezing to obtain virgin flaxseed oil and a squeezed cake; adsorbing and deacidifying the primary oil through modified diatomite to obtain refined oil; carrying out ethanol solution ultrasonic extraction and supercritical CO2 extraction on the pressed cake to obtain a high-purity vitamin E extract; and finally, mixing the extract with the refined linseed oil to obtain the linseed oil. Through the whole-process low-temperature, physical adsorption and efficient extraction and purification process, the retention rate and enrichment degree of vitamin E are remarkably improved, meanwhile, nutritional ingredients such as alpha-linolenic acid are effectively protected, use of synthetic antioxidants is avoided, and the product has the advantages of being high in oxidation stability, good in safety, excellent in sensory quality and the like and is suitable for industrial production. The edible oil is suitable for being used as a nutritional supplement, edible oil or food additive.
Owner:INNER MONGOLIA GREENNOER BIOLOGICAL CO LTD

Preparation method and application of carbon dot-based nano enzyme

The invention relates to a preparation method and application of a carbon dot-based nano enzyme. The preparation method of the carbon dot-based nano-enzyme comprises the following steps: taking sucralose and B vitamins as raw materials, and preparing the carbon dot-based nano-enzyme through a one-pot hydrothermal method. The preparation method of the carbon dot-based nano-enzyme provided by the invention is simpler in catalytic condition and higher in safety. The carbon dot-based nano-enzyme prepared by the invention has the advantages of high oxidase-like activity, low drug resistance, high biocompatibility and the like, can inhibit multi-drug-resistant bacteria, and can be applied to the aspects of aquatic product preservation and the like.
Owner:BOHAI UNIV

Exosome compound preparation with hair growth effect and preparation method thereof

The invention relates to the technical field of exosomes, in particular to an exosome compound preparation with a hair growing effect and a preparation method of the exosome compound preparation. Comprising 12 to 22 parts of ginsenoside Rb1, 15 to 12 parts of biotin tripeptide-15, 8 to 15 parts of diammonium glycyrrhizinate, 50 to 70 parts of fish collagen peptide, 10 to 20 parts of soybean peptide, 0.5 to 4.5 parts of SHH protein, 0.5 to 2.5 parts of SMO inhibitor, 0.5 to 1.5 parts of HhSP protein, 5 to 10 parts of N-acetyl tyrosine, 0.1 to 2 parts of hyaluronic acid, 0.1 to 1 part of melatonin, 0.1 to 1 part of quercetin, 0.1 to 1 part of kaempferol, 0.1 to 1 part of tanshinone, 0.1 to 1 part of biotin and 0.1 to 1 part of vitamin A. The compound preparation is combined with exosomes from various sources, so that the hair papilla cell function is synergistically enhanced, and the damaged hair follicle structure is repaired.
Owner:SHANGHAI CHUNSHEN EXOSOME BIOMEDICINE CO LTD

Vitamin D3 hydroxylase mutant and application thereof in preparation of 25-hydroxyvitamin D3

The invention belongs to the technical field of gene engineering, and particularly relates to a vitamin D3 hydroxylase mutant and application thereof in preparation of 25-hydroxyvitamin D3. According to the invention, the vitamin D3 hydroxylase Vdh-K1 is subjected to directed mutation, so that the vitamin D3 hydroxylase mutants VM, MV and VMV with higher activity are obtained. Compared with parent vitamin D3 hydroxylase Vdh-k1, the activities of the mutants VM, MV and VMV are respectively improved by 2.4 times, 1.6 times and 2.2 times, and when the mutant is used for preparing the 25-hydroxyvitamin D3, the conversion rate and the conversion rate of converting VD3 into the 25-hydroxyvitamin D3 are obviously improved.
Owner:SICHUAN UNIV

Lactobacillus rhamnosus BN02 for improving joint inflammation and promoting bone health, metagen and application of lactobacillus rhamnosus BN02 and metagen

The invention discloses a lactobacillus rhamnosus capable of improving joint inflammation and promoting bone health, a metagen and application of the lactobacillus rhamnosus, the lactobacillus rhamnosus is lactobacillus rhamnosus BN02, the lactobacillus rhamnosus is preserved in China General Microbiological Culture Collection Center on November 27, 2023, and the preservation number is CGMCC No.29133. The lactobacillus rhamnosus can be used for improving joint inflammation and promoting bone health. The lactobacillus rhamnosus BN02 can reduce the number of gram-negative bacteria in intestinal tracts of arthritis patients, increase the synthesis amount of bone collagen, and is beneficial to promoting absorption of vitamin C by the intestinal tracts, improving joint inflammation and promoting bone health.
Owner:湖南益百益优生物科技有限公司

Short peptide from undaria pinnatifida and application thereof

The invention discloses an oligopeptide from undaria pinnatifida and application thereof. The amino acid sequence of the oligopeptide is YRKD, and the molecular weight is 580.63 g / mol. The polypeptide is identified from undaria pinnatifida through a high performance liquid chromatography technology for the first time, and an unreported oligopeptide capable of inhibiting tyrosinase and cooperating with vitamin C to synergistically inhibit tyrosinase is screened out. The oligopeptide derived from undaria pinnatifida is synthesized by a solid phase method, has the characteristics of safety, no toxicity, good water solubility and good stability, and is combined with vitamin C to generate a synergistic effect and synergistically increase the inhibition effect on tyrosinase, so that the oligopeptide can achieve a better tyrosinase inhibition effect at a lower and more stable concentration; the use concentration of the oligopeptide can be greatly reduced, the stability is enhanced, and the oligopeptide can be widely applied to preparation of cosmetics, medicines, health-care products or food additives, and has important economic value and social significance.
Owner:GUANGZHOU TAIWEI FEED CO LTD

Aqueous solution for scalp care and preparation method thereof

The invention relates to the related technical field of daily chemical skin care products, in particular to a water aqua solution for scalp care and a preparation method thereof.The water aqua solution is prepared by mixing multiple raw materials in sequence, and the multiple raw materials comprise, by concentration, 0.005% of mixed cytokines, 0.005% of auxiliary agents and the balance water. The addition amount of the vitamin B12 is 0.00006%; the addition amount of allantoin is 0.2%; the addition amount of nicotinamide is 0.7%; the adding amount of the chamomile extracting solution is 5%; the adding amount of the aloe extracting solution is 5%; the addition amount of the ginkgo biloba extract is 5%; the addition amount of the lucid ganoderma extracting solution is 5%; the addition amount of the polyol preservative is 1%; the total percentage is 100%; according to the application, the mixed cell factors, the vitamin B12, the allantoin, the nicotinamide, the chamomile extracting solution, the aloe, the gingko, the lucid ganoderma, the polyol preservative and the water are mixed, so that the scalp absorption efficiency is improved, the safety of the product can be improved, and the maintenance effect is more obvious; the problems that an existing aqueous solution for skin curing is low in component action efficiency and insufficient in adaptability and safety are solved.
Owner:TIANJIN BONA GENE BIOTECHNOLOGY CO LTD

Wound dressing for diminishing inflammation, easing pain and promoting wound healing and preparation method thereof

The invention provides a wound dressing for diminishing inflammation, easing pain and promoting wound healing and a preparation method thereof. The wound dressing capable of diminishing inflammation, easing pain and promoting wound healing is prepared from the following components in parts by mass: 6 to 10 parts of oxidized sodium alginate, 7 to 9 parts of hydrazide gelatin, 1 to 1.5 parts of tannic acid, 8 to 12 parts of polyethylene glycol, 0.05 to 0.1 part of cannabidiol, 0.05 to 0.1 part of neomycin sulfate, 0.2 to 0.3 part of 2-roots alcohol, 0.02 to 0.04 part of vitamin C palmitate and 0.03 to 0.1 part of epsilon-polylysine. The dressing can achieve excellent effects of diminishing inflammation, easing pain and promoting wound healing through synergistic cooperation of all the components.
Owner:GUANGDONG YUNZHAO MEDICAL TECH CO LTD

Polyethylene glycol glycerol ricinoleate granules as well as preparation method and application thereof

The invention relates to polyethylene glycol glycerol ricinoleate granules as well as a preparation method and application thereof. The granules comprise first polyethylene glycol glycerol ricinoleate with an HLB (Hydrophile-Lipophile Balance) value of 17-19, second polyethylene glycol glycerol ricinoleate with an HLB value of 12-14, a carrier and vitamin E acetate. According to the invention, fatty acid and / or hydrogenated vegetable oil are / is taken as a nutritional carrier, and polyethylene glycol glycerol ricinoleate with an HLB value of 12-14 is introduced, so that the dispersity of active ingredients with a high HLB value (17-19) in the carrier is effectively improved, and granulation is facilitated; meanwhile, the vitamin E acetate is added, so that the immunity of animals can be enhanced while the effects of resisting oxidation and prolonging the shelf life of the product are achieved. The granules solve the problems that pure products are not easy to mix, inconvenient to use and the like.
Owner:JIANGSU HANJING BIOTECHNOLOGY CO LTD

Monoclonal antibody 34C1 for resisting vitamin B12 and application of monoclonal antibody 34C1

The invention provides a monoclonal antibody 34C1 for resisting vitamin B12. The sequence of a heavy chain CDR1 of the monoclonal antibody 34C1 is as shown in SEQ ID NO: 1, the sequence of CDR2 of the monoclonal antibody 34C1 is as shown in SEQ ID NO: 2, and the sequence of CDR3 of the monoclonal antibody 34C1 is as shown in SEQ ID NO: 3; the sequence of the light chain CDR1 is shown as SEQ ID NO: 4, the sequence of the CDR2 is shown as SEQ ID NO: 5, and the sequence of the CDR3 is shown as SEQ ID NO: 6. The antibody can specifically recognize VB12, and can be developed into an immunodetection reagent based on a competition law principle or a sandwich law principle.
Owner:XIAMEN KANGJI BIOTECHNOLOGY CO LTD

Composition for assisting in reducing blood sugar and improving insulin resistance and preparation method thereof

The invention provides a composition for assisting in reducing blood sugar and improving insulin resistance and a preparation method of the composition, and relates to the technical field of functional fiber processing. The composition for assisting in reducing blood sugar and improving insulin resistance comprises the following raw materials in parts by weight: 10-15 parts of depolymerization type composite cereal fibers, 3-5 parts of konjac fibers, 3-5 parts of psyllium husk powder, 2-3 parts of sesame powder, 1-2 parts of xylitol and 0.1-0.5 part of vitamin C, the mass ratio of wheat fiber to corn fiber to sweet potato fiber to pea fiber in the depolymerization type composite grain fiber is (25-30): (35-40): (20-25): (10-15). The composition disclosed by the invention can assist in reducing blood sugar and has a good effect of improving insulin resistance.
Owner:GUILIN GUSHAN FOOD TECH CO LTD

Modified biogas residue-based hydrothermal carbon, preparation method thereof and dry digestion method of kitchen waste

The invention discloses modified biogas residue-based hydrothermal carbon, a preparation method thereof and a dry digestion method for kitchen waste, and belongs to the technical field of waste organic matter recycling. The preparation method comprises the following steps: soaking biogas residues in a phosphoric acid solution to obtain pretreated biogas residues; mixing the pretreated biogas residues, transition metal salt, biochar loaded with vitamin B12 and water with the mass being 8-15 times that of the pretreated biogas residues, and performing hydrothermal reaction for 1-4 hours under the conditions that the temperature is 180-250 DEG C and the pressure is 1.5-4 MPa to obtain a hydrothermal product; and activating the hydrothermal product for 1-2 hours under the protective atmosphere of 300-400 DEG C to obtain the modified biogas residue-based hydrothermal carbon. The surface Fe-Cu composite oxide sequentially catalyzes and oxidizes H2S into elemental sulfur and sulfate ions, the vitamin B12-loaded biochar can promote MA directional proliferation, the sulfate ions can competitively inhibit SRB substrate uptake, the quantity ratio of MA to SRB is increased, and the methane production efficiency is effectively improved.
Owner:QINGDAO UNIV OF TECH

Nutrient solution capable of increasing vitamin C of plants and preparation method of nutrient solution

The invention discloses a nutrient solution capable of increasing vitamin C of plants and a preparation method of the nutrient solution, and relates to the technical field of plant nutrition and fertilizers. The nutrient solution contains additives such as 2-keto-L-gulonic acid or 2-keto-L-gulonic acid salt and the like. According to the invention, 2-keto-L-gulonic acid or 2-keto-L-gulonic acid sodium or 2-keto-L-gulonic acid potassium and the like are used as core raw materials of the nutrient solution for plants, and are compounded with basic nutrient raw materials and additives required by the plants to prepare the plant nutrient solution and the composite nutrient solution. The 2-keto-L-gulonic acid and the 2-keto-L-gulonate in the plant body can be catalyzed and converted into the vitamin C, so that the content of the vitamin C in the tree body is remarkably increased.
Owner:SHENYANG INST OF APPL ECOLOGY CHINESE ACAD OF SCI

Modified hydroxytyrosol, preparation method and application

The invention discloses modified hydroxytyrosol as well as a preparation method and application thereof. The provided preparation method of the modified hydroxytyrosol comprises the following steps: in the presence of an acidic buffer solution, mixing hydroxytyrosol and vitamin C ethyl ether, and carrying out a dehydration condensation reaction to prepare the modified hydroxytyrosol. According to the provided preparation method of the modified hydroxytyrosol, the vitamin C ethyl ether is adopted to modify the hydroxytyrosol, the preparation method is simple and easy to operate, and the prepared modified hydroxytyrosol has high oxidation resistance and inflammation resistance.
Owner:HANGZHOU MEILIMEI BIOTECHNOLOGY CO LTD

Fusion P450 enzyme mutant, method for improving VD3 catalytic activity and method for generating 25 (OH) VD3 by whole cells

The invention relates to the technical field of agricultural biology, in particular to a fusion P450 enzyme mutant, a method for improving VD3 catalytic activity and a method for generating 25 (OH) VD3 through whole cells. The invention constructs a fusion P450 enzyme VK1-CYP116B46-L21 and a self-sufficiency fusion P450 enzyme mutant with improved activity, wherein the self-sufficiency fusion P450 enzyme mutant is used for catalyzing vitamin D3 to synthesize calcifediol; vD3 is taken as a substrate, glucose, a cosolvent and a wet thallus induced by recombinant escherichia coli for simultaneously expressing fusion P450 enzyme and glucose dehydrogenase are added, and the highest yield of 25 (OH) VD3 within 24 hours after catalytic reaction can reach 3.26 g / L; whole cells are directly used as a catalyst, enzyme purification is not needed, glucose dehydrogenase is introduced, and glucose is used as a substrate to regenerate a cofactor NAD (P) H, so that addition of expensive cofactors is avoided, the production cost is reduced, and industrial production is facilitated.
Owner:INSTITUTE OF ANIMAL SCIENCES OF CHINESE ACADEMY OF AGRICULTURAL SCIENCES

Method for increasing rice yield

The invention belongs to the technical field of plant genetic engineering, discloses a method for increasing the yield of rice, and aims to solve the technical problem that the yield is reduced due to reduction of photosynthetic efficiency caused by light inhibition of rice under high-light-intensity illumination. According to the method, the expression quantity of the OsJAB1 gene in a target plant is increased, the content of vitamin C in the plant is increased, the photosynthetic electron transfer efficiency is improved, dry matter accumulation and grain development are promoted, and finally the rice yield is increased.
Owner:SANYA NATIONAL INSTITUTE OF SOUTHERN BREEDING CHINESE ACADEMY OF AGRICULTURAL SCIENCES +1

Color protection and vitamin retention method for green peppers in green pepper and pork tripe prefabricated dish

The invention relates to the technical field of prefabricated dishes, and discloses a color-protecting and vitamin-retaining method for green peppers in green pepper and pig tripe prefabricated dishes, which comprises the following steps: selecting fresh green peppers, sorting, cleaning, and soaking with a citric acid-calcium chloride mixed solution to obtain pretreated green peppers; performing vacuum pre-cooling on the pre-treated green peppers to obtain pre-cooled green peppers; selecting fresh pork tripe, cleaning, and marinating with spices to obtain marinated pork tripe; mixing the precooled green peppers with the marinated pork tripe, then packaging the mixture by adopting vacuum packaging to obtain a vacuum-packaged green pepper and pork tripe prefabricated dish, and finally performing low-temperature sterilization to obtain the green pepper and pork tripe prefabricated dish. The green peppers are soaked in the citric acid-calcium chloride mixed solution, and low-temperature vacuum pre-cooling is performed, so that degradation of chlorophyll is reduced, the color of the green peppers is protected, and vitamins are reserved at the same time.
Owner:HUNAN PENGJIFANG AGRI TECH DEV CO LTD

Test strip for detecting uric acid in saliva, preparation and detection method therefor and use thereof

A test strip for detecting uric acid in saliva that meets the requirement for room-temperature preservation, a preparation and detection method therefor and the use thereof. The test strip for detecting uric acid in saliva comprises a uricase, a peroxidase, a vitamin C oxidase, a bilirubin oxidase, a color developing agent, and a protective film coated on the test strip for detecting uric acid in saliva. To meet the needs of a target population for long-term monitoring and real-time tracking of changes in their uric acid levels, by means of agent addition, the test strip for detecting uric acid in saliva has prolonged preservation time at room temperature, enables non-invasive, efficient and convenient monitoring of a health status at any time, and timely detection and treatment, allows intuitive visual identification of uric acid levels in saliva by a subject, and meets the needs of a subject for long-term preservation at room temperature.
Owner:ZHONGKE KANGCI MEDICAL TECH SUZHOU CO LTD

High-water-solubility denitroflavin covalent complex as well as preparation method and application of high-water-solubility denitroflavin covalent complex

The invention relates to a high-water-solubility denitroflavin covalent complex as well as a preparation method and application thereof, and belongs to the technical field of organic synthesis and medicinal chemistry. Comprising the following steps: (1) firstly, carrying out bromination reaction on 3-methyl-10-ethyl denitroflavin, so as to obtain 3-methyl-10-(1-bromoethyl) denitroflavin; and (2) coupling the 3-methyl-10-(1-bromoethyl) denitroflavin with vitamin C, so as to obtain the high-water-solubility denitroflavin covalent complex. According to the present invention, the prepared highly water-soluble denitrificin covalent complex has the two-phase solubility of the organic solvent and the water, such that the water solubility of the 3-methyl-10-ethyl-denitrificin is substantially enhanced, and the application range of the denitrificin is expanded. And meanwhile, the denitrified flavin covalent compound also has good antioxidant activity, and the antioxidant duration can be prolonged.
Owner:SHANDONG FENGJIN MEIYE TECH CO LTD

Calculus bovis intermediate and preparation method of calculus bovis

PendingCN121227829AOrganic active ingredientsOrganic chemistryBiliverdinConjugated bilirubin
The invention belongs to the technical field of biochemical pharmacy, and particularly relates to a bezoar intermediate and a preparation method of bezoar. The preparation method comprises the following steps: mixing preparation raw materials and biochemical reaction liquid to obtain a mixed raw material solution; the preparation raw materials comprise bilirubin, organic active raw materials and vitamins, the biochemical reaction liquid is sterile purified water, and the bilirubin comprises bilirubin or biliverdin; and reacting the mixed raw material solution to obtain the bezoar intermediate. The content of combined bilirubin in the bezoar intermediate prepared by the preparation method provided by the invention is 75%-85%, the content of combined biliverdin is 73%-83%, and the yield is 83%-87%. According to the method, the poisoning and destroying effects of mycotoxin on the content, the yield, the biological activity and the oxidation resistance of the bezoar intermediate are effectively eliminated. The content, the yield, the oxidation resistance and the biological activity of the bezoar intermediate are greatly improved, the performance is stable, and the quality of bezoar is ensured.
Owner:王晨旭 +3

Lactating sow feed containing fermentation raw materials and preparation method thereof

The invention relates to the technical field of feed processing, and discloses a lactating sow feed containing fermentation raw materials and a preparation method of the lactating sow feed. A three-layer microcapsule coating auxiliary material is prepared by taking a vitamin premix, an amino acid compound, a compound enzyme preparation and a probiotic agent as core materials through three-layer coating; the basic raw materials comprise corn, wheat, bran, a fermentation raw material, a mineral premix and grease, auxiliary material coating and basic raw material treatment are carried out in parallel in double lines during preparation, and finally, mixing granulation is carried out; the grafted copolymer formed by the amidation reaction of the sodium carboxymethyl cellulose and the chitosan oligosaccharide can cooperate with the sodium alginate to prevent the damage under acidic conditions, and the survival rate of viable bacteria is kept at 85-87% after treatment is carried out for 2 hours under the acidic condition with the pH value of 2.0-3.0; compared with a traditional fermentation raw material coating scheme, the dosage of coating raw materials is reduced by 70% or above; meanwhile, the vitamin premix and the amino acid compound in the auxiliary material can reduce the diarrhea rate by 6% and increase the lactation yield of the sow by 7-18%.
Owner:ANHUI TECH-BANK FEED IND CO LTD

Composition with functions of protecting gingiva and repairing enamel and preparation method thereof

The invention relates to a composition with functions of protecting gingiva and repairing enamel and a preparation method of the composition, and belongs to the technical field of oral care. The composition contains a functional additive, a plant compound fermentation extract and the like, the functional additive is a mixture of corn starch, calcium phosphosilicate, hydroxyapatite, ubiquinone, sodium guaiazulene sulfonate, menthol and vitamin E, and the plant compound fermentation extract is obtained by fermenting and purifying honeysuckle flowers, radix polygonati officinalis and dandelions according to a specific proportion. Through the synergistic effect of the fermentation extract and the functional components, the problems that an existing toothpaste body is hardened, the storage stability is poor, the gingival protecting effect is short, and the enamel repairing persistence is insufficient are solved, the gingival protecting effect can be enhanced, the enamel repairing effect can be improved, the stability of the toothpaste body can be optimized, the antibacterial property and the oral mucosa relieving effect are achieved, and the oral cavity repairing effect is achieved. And the preparation process is scientific and reasonable, and is suitable for daily oral care.
Owner:GUANGZHOU HEJIA PHARMACEUTICAL CO LTD

Composition for treating large yellow croaker pyramidoniasis as well as preparation method and application thereof

The invention relates to a composition for treating large yellow croaker pyramidoniasis as well as a preparation method and application thereof, and belongs to the technical field of aquaculture. The composition comprises the following components: curcumin, bile acid, beta glucan, bacillus subtilis freeze-dried powder, marine red yeast freeze-dried powder, vitamin C, vitamin E and ethylicin. When the feed additive is added into basal feed to feed large yellow croakers infected with the trypanosomiasis, the death rate of sick fishes can be effectively reduced, the polypide loading capacity is remarkably reduced, and pathological injuries of livers and spleens of the large yellow croakers are relieved. In addition, the composition can also improve the non-specific immunity of the fish body, improve the liver function, enhance the antioxidant capacity of the liver, and improve the lipase activity of the intestinal tract at the same time. Therefore, the composition can be used as a medicine or a feed additive for treating the large yellow croaker pyramidoniasis, has the advantages of small dosage and remarkable effect, and provides a new technical approach for solving the problem that the current large yellow croaker pyramidoniasis lacks an effective prevention and control means.
Owner:JIMEI UNIV

Composition containing D-chiro-inositol as well as preparation method and application thereof

The invention discloses a composition containing D-chiro-inositol as well as a preparation method and application of the composition. The composition comprises D-chiro-inositol, Myo-inositol and microcapsule powder, wherein the wall material of the microcapsule powder consists of anhydride modified edible protein and a polysaccharide compound; the edible protein is selected from at least one of spirulina protein, quinoa protein, whey protein and soybean protein; the polysaccharide compound comprises at least one of fucoidin and larch arabinogalactan. Active components are also embedded in the microcapsule powder, and comprise at least one of Omega-3, coenzyme Q10, astaxanthin and vitamin. According to the composition, the stability and bioavailability of fat-soluble active ingredients are improved through microencapsulation, and the composition has a synergistic effect with components such as D-chiro-inositol and Myoinositol, so that insulin resistance is effectively improved, female hormone balance is adjusted, and polycystic ovarian syndrome is improved. The process is simple, is suitable for large-scale production, and can be widely applied to dietary supplements or functional foods.
Owner:HANG ZHOU HE TAN CHUANG WU KE JI YOU XIAN GONG SI +2

Liquid chromatography-mass spectrometry tandem detection method for multiple folic acid metabolism related substances in trace plasma or serum

The invention belongs to the technical field of biological detection, and particularly relates to a method for synchronously and quantitatively detecting various folic acid metabolism related substances in trace plasma or serum, which comprises the following steps of: detecting a pretreated trace plasma or serum sample by adopting a liquid chromatography-tandem mass spectrometry method; the following nine folic acid metabolism related substances are synchronously and quantitatively detected: 5-formyl tetrahydrofolic acid, folic acid, 5-methyl tetrahydrofolic acid, S-adenosine-L-methionine, S-adenosine-L-homocysteine, vitamin B12, pyridoxamine, pyridoxine and pyridoxal. The invention further relates to application of the detection method in related detection of child neurodevelopment. According to the detection method, only trace plasma or serum is used, methotrexate is used for replacing an expensive isotope internal standard for more economical detection, and nine folate metabolism related substances can be accurately quantified at the same time. Therefore, the detection method disclosed by the invention has important clinical significance and wide market application prospect.
Owner:PEKING UNIV