Patents
Literature
Patsnap Eureka AI that helps you search prior art, draft patents, and assess FTO risks, powered by patent and scientific literature data.

6747 results about "Vitamin" patented technology

A vitamin is an organic molecule (or related set of molecules) that is an essential micronutrient that an organism needs in small quantities for the proper functioning of its metabolism. Essential nutrients cannot be synthesized in the organism, either at all or not in sufficient quantities, and therefore must be obtained through the diet. Vitamin C can be synthesized by some species but not by others; it is not a vitamin in the first instance but is in the second. The term vitamin does not include the three other groups of essential nutrients: minerals, essential fatty acids, and essential amino acids. Most vitamins are not single molecules, but groups of related molecules called vitamers. For example, vitamin E consists of four tocopherols and four tocotrienols. The thirteen vitamins required by human metabolism are: vitamin A (as all-trans-retinol, all-trans-retinyl-esters, as well as all-trans-beta-carotene and other provitamin A carotenoids), vitamin B₁ (thiamine), vitamin B₂ (riboflavin), vitamin B₃ (niacin), vitamin B₅ (pantothenic acid), vitamin B₆ (pyridoxine), vitamin B₇ (biotin), vitamin B₉ (folic acid or folate), vitamin B₁₂ (cobalamins), vitamin C (ascorbic acid), vitamin D (calciferols), vitamin E (tocopherols and tocotrienols), and vitamin K (quinones).

Noodle with blood sugar control function and preparation method thereof

The invention discloses noodles with a blood sugar control function, which comprise the following components in parts by weight: 150-170 parts of triticale flour, 10-30 parts of cyperus esculentus powder, table salt and water, and 4-10 parts of dietary fibers, 0.5 to 1 part of anthocyanin; 0.03 to 0.12 part of mineral substances and 0.2 to 0.5 part of vitamin B. The traditional Chinese medicine composition has the effects of improving digestion and metabolism, delaying senescence, strengthening body functions, assisting in controlling blood sugar, enhancing satiety and assisting weight management.
Owner:XIANGYANG SHENGHAI CULTURAL TOURISM SUPPLIES CO LTD

Pharmaceutical composition containing melogabalin besylate and preparation method thereof

The invention discloses a pharmaceutical composition containing melogabalin besylate and a preparation method of the pharmaceutical composition. Belongs to the technical field of pharmaceutical preparations. Comprising melogabalin besylate and pharmaceutically acceptable auxiliary materials, the pharmaceutically acceptable auxiliary materials comprise a filler, a disintegrating agent, an adhesive, an antioxidant and a lubricant, the antioxidant comprises vitamin E succinic acid polyethylene glycol ester, and the lubricant comprises vitamin E succinic acid polyethylene glycol ester. The melogabalin besylate as the active ingredient accounts for 2-15% by weight of the pharmaceutical composition, preferably 2-10% by weight of the pharmaceutical composition. According to the pharmaceutical composition, antioxidant particles are prepared by adopting a fluidized bed granulation process, raw material medicines, the antioxidant particles and other auxiliary materials are mixed, tableted and coated, an antioxidant comprises vitamin E succinic acid polyethylene glycol ester and tartaric acid, and the prepared tablet has good stability.
Owner:QILU PHARMA HAINAN +1

Intelligent data retrieval optimization method based on large model and deep learning

The invention provides an intelligent data retrieval optimization method based on a large model and deep learning. The method comprises the following steps: performing data cleaning, labeling and index construction on original data; performing semantic analysis on user query by using a large-scale pre-training language model to generate deep semantic representation of the query; performing semantic matching in a distributed database according to deep semantic representation queried by a user, and retrieving related high-dimensional feature vectors; classifying and sorting the matched high-dimensional feature vectors through a deep learning network; dynamically adjusting parameters of the pre-training language model and the deep learning network in combination with online learning and a real-time feedback mechanism; and a cache strategy and an index optimization technology are adopted, and a retrieval result most relevant to user query is output. According to the method, by combining an advanced language model and a deep learning technology, efficient and accurate intelligent data retrieval is realized, and the retrieval experience of a user is remarkably improved.
Owner:HANGZHOU SHUHAN TECH CO LTD

Personalized diagnosis method for intestinal flora and obesity based on graph attention network

The invention discloses an intestinal flora and obesity personalized diagnosis method based on a graph attention network, and relates to the technical field of obesity diagnosis, and the method comprises the following steps: collecting gene data, building a graph structure-based model for the data to predict obesity risk and provide personalized health suggestions, each piece of microbiome data is expressed as a weighted undirected graph, a microbiome graph is constructed, the association strength between microbiome groups is calculated, and the microbiome data is expressed as a graph structure. According to the method, the graph structure model considering the relevance between the microbiome groups is constructed, the self-adaptive graph convolutional network and the heterogeneous graph attention network are utilized, multi-modal information interaction between the microbiome and clinical data is deeply mined, the processing capacity of high-dimensional and complex microbiome data is improved, and the multi-modal information interaction between the microbiome and clinical data is improved. The accurate prediction of obesity risks and the provision of personalized health suggestions are realized, the prediction accuracy and generalization ability of the model are significantly improved, and a more effective personalized obesity diagnosis effect is achieved.
Owner:SHANGHAI BAO PUZI HEALTH TECHNOLOGY CO LTD

Optical detection method and system for content of vitamin tablets

The invention relates to the technical field of medicine quality detection, and particularly discloses an optical detection method and system for the content of vitamin tablets. The method comprises the following steps: driving an optical fiber probe array to carry out three-dimensional multi-angle near-infrared scanning through a multi-axis mechanical arm, and collecting reflection spectrum data; a weighted spectrum is generated through derivative spectrum analysis and double evaluation, and auxiliary material noise is corrected and separated in combination with subspace projection and a dynamic kernel function; performing spectral vector projection and regression coefficient iterative optimization through an online PLS model, and synthesizing an error coefficient based on a four-level index retrieval standard library to perform dual-channel feedback; and finally, fusing the credibility weight to output a detection result of the binding confidence. The method realizes nondestructive and high-precision detection of the vitamin tablets, has the beneficial effects of multi-dimensional data fusion, dynamic error compensation and high model adaptability, and remarkably improves the detection accuracy and reliability.
Owner:CSPC ZHONGNUO PHARM (TAIZHOU) CO LTD

High-activity lactobacillus rhamnosus probiotic microcapsule and application thereof

The invention relates to the technical field of biological medicines, and discloses a high-activity lactobacillus rhamnosus probiotic microcapsule, which comprises the following components in parts by weight: lactobacillus rhamnosus: each gram of formula contains 1010 CFU; bifidobacterium: each gram of the formula contains 109 CFU; 10% to 20% of sodium alginate; 5%-15% of chitosan; 3%-8% of hydroxypropyl methyl cellulose; 3%-7% of pectin; 5% to 10% of fructo-oligosaccharide; 5%-10% of inulin; 0.1%-0.5% of vitamin C; and 0.1%-0.3% of vitamin E. Through double-layer and three-layer embedding technologies (such as compound use of sodium alginate and chitosan and compound use of pectin and gelatin), the tolerance of the probiotics in gastric acid and bile environments is remarkably improved, the probiotics are effectively protected through a multi-layer embedding structure, the survival rate of the probiotics in the gastric environment reaches up to 90%, and the release rate in the small intestine exceeds 75%.
Owner:HENAN BUSINESS SCI RES INST

Novel association of active ingredients, pharmaceutical and / or nutraceutical compositions containing it and their use in the prevention and repair of damage to the central and peripheral nervous system

PCT designated stage expiredWO2025146608A1Nervous disorderAntipyreticNervous systemNutrition
The present invention relates to a novel association or combination of active ingredients useful in the prevention and repair of neuronal damage, both centrally and peripherally. In greater detail, the present invention relates to an association or combination of i) an extract of Gastrodia elata and ii) at least one ingredient selected from the group comprising or, alternatively, consisting of citicoline, L-acetylcarnitine and, preferably, at least one vitamin of group D, and / or mixtures thereof, and / or at least one vitamin of group B, and / or mixtures thereof. Furthermore, the invention also relates to the pharmaceutical compositions and / or compositions for medical devices (Regulation (EU) 2017 / 745) and / or nutraceutical and / or food compositions comprising that association and to their use in therapy, in particular in the protection of the functionality of the nervous system and in the prevention and / or treatment of central and peripheral neuropathies.
Owner:FUTURA S R L SOVICO

Synthesis method of vitamin C ethyl ether

The invention discloses a synthesis method of vitamin C ethyl ether, and belongs to the technical field of vitamin derivative synthesis. The synthesis method comprises the following steps: adding vitamin C, benzaldehyde and a catalyst into a first organic solvent, carrying out an aldolization reaction, adding an organic alkali after the aldolization reaction is finished, carrying out a neutralization reaction, adding an alkylation reagent, carrying out an alkylation reaction, and removing the first organic solvent after the alkylation reaction is finished, so as to obtain the vitamin C benzaldehyde. The preparation method comprises the following steps: adding a first organic solvent into a first organic solvent, pulping, filtering, collecting filter residues, washing and drying to obtain 5, 6-O-benzyl-3-O-ethyl-L-ascorbic acid, carrying out hydrogenation deprotection on the 5, 6-O-benzyl-3-O-ethyl-L-ascorbic acid, filtering after hydrogenation deprotection, collecting filtrate, crystallizing, collecting precipitate, washing and drying to obtain the 5, 6-O-benzyl-3-O-ethyl-L-ascorbic acid. The vitamin C ethyl ether is obtained. The synthesis method provided by the invention is simple to operate and high in production efficiency, and the obtained vitamin C ethyl ether is high in yield and purity.
Owner:HUANGPU INST OF MATERIALS

Roe polypeptide essence water

The invention discloses roe polypeptide essence water, which is prepared from a water phase component, an active component, an oil phase component, a stabilizer and a thickening agent, the water phase component is prepared from the following components in parts by mass: 60 to 150 parts of purified water, 3 to 7 parts of glycerol, 2 to 5 parts of propylene glycol, 1 to 2 parts of panthenol and 0.1 to 0.3 part of sodium hyaluronate; the oil phase component is prepared from the following components in parts by mass: 2 to 4 parts of squalane, 1 to 3 parts of jojoba oil and 0.5 to 2 parts of shea butter; the active components comprise the following components in parts by mass: 2 to 5 parts of roe extract, 0.5 to 2 parts of argireline, 0.1 to 0.5 part of oligopeptide-1, 1 to 3 parts of collagen, 0.5 to 2 parts of elastin and 2 to 5 parts of nicotinamide; 0.1 to 0.3 part of hydroxyethyl cellulose is adopted as the stabilizer; 0.2 to 0.5 part of carbomer is adopted as the thickening agent. The roe extract is rich in proteins, amino acids, fatty acids, vitamins and trace elements, and is helpful for nourishing the skin so as to provide the effects of nourishing, resisting aging, moisturizing, brightening the skin color and repairing the skin.
Owner:SKASIDE (HUIZHOU) BIOTECHNOLOGY CO LTD

Lactobacillus plantarum 9A-2 and application thereof in preparation of products for regulating intestinal tracts and protecting eyes

The invention belongs to the technical field of microorganisms, and particularly relates to lactobacillus plantarum 9A-2 and application thereof in preparation of products for regulating intestinal tracts and protecting eyes. A probiotic product is successfully researched and developed on the basis of the lactobacillus plantarum, and verification shows that the lactobacillus plantarum can continuously provide endophytic essential isorhamnetin, chromium and vitamin H in the intestinal reproduction and growth process while regulating intestinal flora balance and promoting digestion, and also has the effect of relieving visual fatigue; particularly, visual fatigue caused by eye related diseases is relieved. The endophytic essential quantity of isorhamnetin, chromium and vitamin H can be continuously provided in the intestinal reproduction and growth process by feeding 3 billion strains and 200 milligrams of metabolites of the strain every day, visual fatigue caused by eye related diseases can be prevented and relieved, and the body health can be kept.
Owner:SHANDONG HUANYI BIOTECHNOLOGY CO LTD

Zhejiang camellia japonica clone tissue culture and rapid propagation method

The invention discloses a Zhejiang camellia japonica clone tissue culture and rapid propagation method. A Zhejiang camellia japonica clone tissue culture and rapid propagation technical system is established by taking a non-lignified tender stem as an explant, sterilizing and then performing primary induction, subculture multiplication, strong bud culture and rooting culture. The explants are soaked before primary inoculation, and vitamin C and polyvinylpyrrolidone with certain concentration are added into a primary induction culture medium, so that browning of the explants can be effectively inhibited; hormone regulation and control and nutrient addition are combined, so that the primary induction rate reaches up to 95.3%, the multiplication coefficient reaches about 6.8, the rooting rate reaches 83.5%, efficient and rapid propagation can be realized, and the method is not limited by factors such as seasons, climate and regions. The rapid propagation offspring obtained by the system can maintain all excellent characters of a stock plant, and the strong bud obtained in the process can be used as a scion for grafting propagation, so that a technical support is provided for protection, development and utilization of rare germplasm resources and excellent clone of the Zhejiang red camellia.
Owner:RES INST OF SUBTROPICAL FORESTRY CHINESE ACAD OF FORESTRY

Method for extracting extracellular vesicles from dry sanguisorba officinalis rhizomes and application of extracellular vesicles

The invention discloses a method for extracting extracellular vesicles from dried Sanguisorba officinalis rhizomes and application of the extracellular vesicles, and relates to the technical field of molecular biology and biomedicine.The method comprises the following steps that S1, rehydration is conducted, specifically, the dried Sanguisorba officinalis rhizomes are subjected to liquid nitrogen quick freezing and then ground into powder at the low temperature, the powder and hydration liquid are mixed according to the proportion of 1: 10 (w / v), the mixture is slowly stirred for 2-4 h at the temperature of 4 DEG C, and the extracellular vesicles are obtained; removing large-particle impurities by using sterile gauze or a filter screen, and collecting filtrate; according to the method, through the synergistic effect of multiple enzymolysis and in combination with cellulase, pectinase and the like, the degradation efficiency is remarkably improved, meanwhile, EDTA is chelated with metal ions, and the enzymolysis effect is enhanced. Short-time alternating ultraviolet light is introduced to activate'dormant 'vesicles, so that the yield and the biological activity are improved. Secondly, multiple protection mechanisms, such as vitamin C, EDTA (Ethylene Diamine Tetraacetic Acid), cane sugar, BSA (Bovine Serum Albumin) and an ultraviolet protective agent are adopted, so that the integrity and the biological activity of the vesicles are ensured.
Owner:SHENZHEN UNIV GENERAL HOSPITAL

Livestock feed proportioning method based on livestock growth

The invention discloses a livestock feed proportioning method based on livestock growth, and relates to the technical field of feed proportioning, and the livestock feed proportioning method comprises the following steps: collecting the body temperature and motion track data and environmental temperature and humidity data of livestock individuals, monitoring the concentration of amino acids in digestive tracts, preprocessing the collected data, and generating a standardized biological data set; analyzing the compensation amount of vitamins and trace elements according to the metabolic fingerprint spectrum, and constructing a multi-objective optimization function in combination with an individual growth curve; solving the multi-objective optimization function through a quantum annealing algorithm, and matching local raw material inventory data of block chain evidence storage to generate an optimization strategy; and executing the optimization strategy and detecting the mixing uniformity, and when the mixing uniformity index exceeds a preset mixing uniformity threshold, starting the compensation device to adjust the optimization strategy. According to the invention, through a cooperation mechanism of dynamic nutritional requirement identification and multi-constraint optimization, the precise regulation and control capability of livestock breeding is significantly improved.
Owner:ZHONGJI HI TECH (BEIJING) BIOTECHNOLOGY CO LTD

P450 mutant and application thereof in synthesis of calcifediol

The invention discloses a P450 mutant and application thereof in synthesis of calcifediol, and belongs to the technical field of bioengineering. According to the present invention, the P450 enzyme mutant enzyme is constructed, and the single plasmid three-enzyme co-expression system of the redox partner and the cofactor cycle enzyme is constructed, such that the sufficient electron transport chain is provided for the P450 enzyme, and the calcifediol can be efficiently synthesized under the mild condition by using the vitamin D3 as the substrate; the conversion rate of calcifediol can reach 63.1%, and the conversion rate of the reaction is greatly improved. By adopting the method disclosed by the invention, the catalytic efficiency of the catalyst is improved, and the reaction cost is reduced.
Owner:JIANGNAN UNIV

Composite denitrification accelerant and preparation method thereof

The invention discloses a composite denitrification accelerant and a preparation method thereof, and belongs to the technical field of sewage treatment. The carbon source composite material is prepared from the following raw materials in parts by weight: 30-50% of a carbon source, 2-5% of vitamins, 2-5% of amino acids, 1-3% of a biological stimulant, 1-2% of signal molecules, 1-5% of metal elements, 3-5% of a pH regulator and 25-60% of water. Through metabolites such as vitamins, amino acids and biological stimulants, growth and reproduction of denitrifying bacteria are promoted, and functions of related enzymes in the denitrification process are improved. The signal molecule optimizes the metabolic activity of bacteria by regulating and controlling the expression of genes, related to the denitrification process, of the denitrifying bacteria. The metal ions can enhance the activity of the denitrifying enzyme, so that the efficiency of denitrification treatment is improved. According to the denitrification accelerant, the denitrification process is promoted through the synergistic effect of three aspects of growth and reproduction of denitrifying bacteria, expression of denitrification genes and improvement of activity of denitrification-related enzymes.
Owner:ZHEJIANG FUCHUN ZIGUANG ENVIRONMENTAL PROTECTION CO LTD

Recirculation aquaculture system and method

The present disclosure provides a recirculation aquaculture system and method. The system includes a fish pond and a fiber turntable filtering system. The fiber turntable filtering system can implement can remove large particles in aquaculture water and regularly harvest microalgae, water quality after treatment reaches a fishery aquaculture standard, and 97% of the aquaculture water can be directly recycled. In the present disclosure, during in-situ culture of microalgae and fish, microalgae can convert CO2 exhaled by fish and nutrients such as nitrogen and phosphorus in the aquaculture water into substances of algae cells, such as proteins, polysaccharides, vitamins, and lipids, and release oxygen, so as to quickly improve quality of the aquaculture water; in-situ culture of the microalgae and the fish gives play to the advantages of high photosynthetic efficiency of the microalgae, and the fast-growing microalgae provide a suitable growth environment for the fish.
Owner:QINGHAI PHOTON ECOLOGICAL CO LTD

Melogabalin besylate tablet and preparation method thereof

The invention discloses a melogabalin besylate tablet and a preparation method thereof, a tablet core of the melogabalin besylate tablet comprises melogabalin besylate, a filler, a disintegrating agent, a lubricant and an antioxidant, and the antioxidant comprises sodium ascorbate. Compared with an antioxidant disclosed in the prior art, sodium ascorbate is selected as the antioxidant, so that the content of related substances in the melogabalin besylate preparation can be effectively improved, the growth of main degradation impurities and oxidation impurities is effectively controlled, the stability of the product is improved, and the product is enabled to be quickly dissolved out and good in dissolution uniformity.
Owner:CHENGDU YAOYILIKANG PHARM TECH CO LTD

Culture solution and culture method for ganoderma lucidum

The invention discloses a ganoderma lucidum culture solution and a culture method thereof. Comprising the following raw materials in parts: 30-40 parts of water, 10-20 parts of corn flour, 1-5 parts of ammonium nitrate, 1-5 parts of monopotassium phosphate, 1-5 parts of potassium sulfate, 1-5 parts of boric acid, 1-5 parts of manganese sulfate, 1-5 parts of zinc sulfate, 1-5 parts of copper sulfate, 1-5 parts of ferric sulfate, 1-5 parts of a short-acting growth regulator, 1-5 parts of amino acid, 1-5 parts of vitamins, 1-5 parts of a seaweed extract, 1-5 parts of honey and 1-5 parts of peaches and oranges. The short-acting growth regulator is prepared from gibberellin, auxin and cytokinin according to the ratio of (2-5): (1-8): (2-9), and the amino acid is prepared by mixing isoleucine, lysine, methionine and phenylalanine according to the ratio of (1-5): (2-8): (4-9): (5-7). The nutrient purity of the culture solution can be greatly increased, the fatality rate is reduced, cell elongation and rooting are promoted, plant metabolism and growth can be greatly promoted, and the quality of ganoderma lucidum is improved.
Owner:任海博

Nerve nutrition composition for helping sleep and relieving depression

The invention provides a protein. The protein comprises an amino acid sequence as shown in SEQ ID NO: 1 or SEQ ID NO: 3. Corresponding nucleic acids, vectors, and compositions comprising the proteins are also provided. In some embodiments, the composition comprises recombinant collagen with an amino acid sequence as shown in SEQ ID NO: 1 or 3, gamma-aminobutyric acid, calcium gluconate, zinc gluconate, vitamin, oryzanol, recombinant humanized collagen with an amino acid sequence as shown in SEQ ID NO: 4 and cordyceps sinensis powder. The invention also provides application of the protein and the composition in preparation of products for helping sleep or relieving depression.
Owner:GUANGXI FULAIMING BIOPHARMACEUTICAL CO LED

Vitamin E derivative as well as carrier compound and application thereof

The invention relates to a vitamin E derivative as well as a carrier compound and application thereof. The vitamin E derivative has a structure as shown in a formula (1) and can be connected and combined with different linkers to obtain a carrier for synthesizing polypeptide, the preparation process is simple, and the obtained carrier is good in solubility, stability and recoverability and can be used for efficiently synthesizing high-purity polypeptide with high yield. # imgabs0 #
Owner:GUANGZHOU CONGEN PHARMATEC CO LTD

Preparation method of antibacterial degradable sponge material

The invention relates to the field of sponge materials, and provides an antibacterial degradable sponge material and a preparation method thereof. The material is prepared from protocatechuic acid modified quaternized chitosan, quaternary ammonium salt grafted gelatin, sodium alginate, polyhydroxybutyrate, polycaprolactone, a polylactic acid-glycolic acid copolymer, hexamethylene diisocyanate, a foaming agent, nano cellulose, vitamin E, polyethylene glycol, triethylamine and dimethylformamide. Protocatechuic acid and quaternized chitosan are subjected to amidation modification, and chitosan and gelatin are subjected to quaternization treatment by adopting 2, 3-epoxypropyl trimethyl ammonium chloride, so that the antibacterial property and biodegradability of the material are improved. In the material preparation process, through vacuum degassing, foaming vacuum degree and humidity control and a multi-step drying process, it is ensured that the average pore size of the material is uniform (50-200 microns) and the porosity is high (50%-90%), and the obtained material has excellent antibacterial property and degradability and has wide application value.
Owner:NANTONG FENGSHENG TEXTILE CO LTD

Composition with hypoglycemic function and application thereof

The invention provides a composition with a blood sugar reducing function and application thereof, and belongs to the technical field of diabetes treatment. The composition is prepared from burdock root extract, folium ilicis purpurea extract, hypoglycemic decapeptide, trehalose, sodium benzoate, glycerol, vitamin C and water. The composition disclosed by the invention has a multi-target synergistic effect, and by integrating natural plant extracts and functional peptides, multiple targets related to diabetes mellitus are adjusted, so that the blood sugar level is remarkably reduced, and cholesterol metabolism, oxidative damage and inflammatory response are effectively improved. The composition can be used for treating type 2 diabetes mellitus and has a good clinical application prospect.
Owner:JINAN RUILONGAN BIOTECHNOLOGY CO LTD

Freshwater fish flavored pet flavoring agent and production method thereof

The invention relates to the technical field of flavor agents, and provides a freshwater fish flavor pet flavor agent and a production method thereof, and the freshwater fish flavor pet flavor agent comprises the following components: freshwater fish, an enzyme preparation, reducing sugar, vitamins, amino acids, auxiliary materials and a herbaceous plant aqueous extract. Through scientific raw material selection, enzymic preparation proportion control, multi-element reducing sugar matching, comprehensive vitamin combination, balanced amino acid screening, herbaceous plant aqueous extract addition, nanotechnology wrapping operation and careful adjustment of auxiliary materials, the pet flavoring agent has the effects of special fragrance, rich taste, good palatability, immunity enhancement and the like.
Owner:BEIJING CENT BIOLOGY CO LTD +2

Microbial compound feed additive and preparation method thereof

The invention discloses a microbial compound feed additive, which is prepared from the following ingredients in parts by weight: 35 to 45 parts of traditional Chinese medicine residues, 25 to 35 parts of soybean meal, 15 to 25 parts of bran, 8 to 12 parts of corn flour, 0.3 to 0.7 part of selenium-enriched yeast, 8 to 12 parts of aspergillus niger spore powder, 10 to 15 parts of bacillus subtilis, 6 to 9 parts of lactobacillus plantarum and 5 to 8 parts of candida utilis. The invention relates to the technical field of feed additives, through the synergistic effect of the aspergillus niger, the bacillus subtilis, the lactobacillus plantarum and the candida utilis, the aspergillus niger can generate various enzymes, and decomposition of raw materials and release of nutritional ingredients are facilitated; the bacillus subtilis can enhance the immunity of livestock and poultry and inhibit the growth of harmful bacteria; lactobacillus plantarum can regulate intestinal microecological balance and promote digestion and absorption; candida utilis is rich in protein and vitamins and provides nutrition for livestock and poultry, the four components cooperate with each other, the function limitation of a single strain is broken through, and the health level and production performance of livestock and poultry are comprehensively improved.
Owner:HEBEI SHIXIANG BIOLOGICAL TECH CO LTD

Non-specific peroxygenase mutant, application thereof and preparation method of 25-hydroxyvitamin D3

The invention discloses a non-specific peroxygenase mutant and application thereof and a preparation method of 25-hydroxyvitamin D3, and particularly relates to a protein obtained by taking an amino acid sequence as shown in SEQ ID NO.1 as a starting sequence and mutating amino acid residues as shown in the 20th site and / or the 25th site and / or the 57th site. The catalyst has relatively high catalytic activity and stereocatalysis specific selectivity; according to the method, acetone, vitamin D3, hydrogen peroxide and a non-specific peroxygenase mutant are respectively added into a potassium phosphate buffer solution with the pH value of 7.0-8.0 to form a reaction mixed solution, an oxidation reaction is carried out for 10-50 hours at the temperature of 25-35 DEG C, the 25-hydroxyvitamin D3 is generated, the reaction condition is mild, the reaction operation is simple and convenient, the conversion rate is high, the cost is low, the preparation efficiency of the 25-hydroxyvitamin D3 is greatly improved, and the method is suitable for industrial production. Good industrial application prospects are realized.
Owner:KINGDOMWAY BIOTECH (JIANGSU) CO LTD +2

Feed functional compound for improving saline-alkaline stress resistance of macrobrachium rosenbergii and application of feed functional compound

The invention discloses a feed functional compound for improving salt-alkali stress resistance of macrobrachium rosenbergii and application of the feed functional compound, and belongs to the technical field of aquaculture. The feed functional compound for improving saline-alkaline stress resistance of macrobrachium rosenbergii provided by the invention comprises vitamin D3, betaine and sodium oleate. According to the invention, the absorption promotion effect of vitamin D3 on calcium and phosphorus ions is utilized, so that the ion metabolism disorder of macrobrachium rosenbergii under saline-alkali stress is improved; by utilizing the osmotic pressure regulation capability of betaine, osmotic pressure unbalance under saline-alkali stress is improved, and the energy consumption of osmotic regulation is reduced; the sodium oleate is used for improving energy supply, the membrane structure is adjusted to improve osmotic pressure adjusting capacity, and the three components act together to achieve the purpose of improving salt-alkali stress tolerance of macrobrachium rosenbergii.
Owner:ZHEJIANG DANSHUI FISHERY RESEARCH INSTITUTE (ZHEJIANG DANSHUI FISHERY ENVIRONMENTAL MONITORING STATION)

Citrus medica and cichorium intybus composite solid beverage

The invention discloses a citron and cichorium intybus composite solid beverage, and relates to the technical field of solid beverages, and the solid beverage comprises the following components: 20-30 parts of a citron extract, 50-70 parts of a cichorium intybus extract, 5-10 parts of erythritol, 1-2 parts of vitamin C, 1-2 parts of probiotic powder, 1-2 parts of citric acid, and 1-2 parts of ginger powder. According to the citron and cichorium intybus composite solid beverage, the cichorium intybus extract in the citron and cichorium intybus composite solid beverage is rich in dietary fibers and can help to improve intestinal health and promote digestion, citron and cichorium intybus contain rich antioxidant components and are beneficial to neutralizing free radicals and slowing down the aging process, and the components in the beverage can help to improve energy and promote digestion. The physical and mental states are improved.
Owner:崔海英

Effect of Collagen in relieving damage of vomitoxin to bovine rumen epithelial cells by vitamin E

The invention discloses an effect of Collagen in relieving vomitoxin injury of bovine rumen epithelial cells by vitamin E, and belongs to the technical field of genetic engineering, the Collagen is COL1A1 protein, COL2A1 protein and COL5A1 protein; the amino acid sequence of the COL1A1 protein is as shown in SEQ ID NO. 19; the amino acid sequence of the COL2A1 protein is as shown in SEQ ID NO. 20; the amino acid sequence of the COL5A1 protein is as shown in SEQ ID NO. 21. According to the effect of Collagen in relieving bovine rumen epithelial cells damaged by vomitoxin through vitamin E, it is found that vitamin E can effectively protect the cell membrane integrity of the bovine rumen epithelial cells and can relieve cell viability decline, oxidative stress, immune and inflammatory reactions and the cell apoptosis rate caused by DON; vitamin E can promote ECM receptor effect and protein digestion and absorption ways by adjusting Collagen protein so as to protect rumen epithelial cells of dairy cows.
Owner:JILIN AGRICULTURAL UNIV

Eutectic microcapsule wrapping technology and application thereof in cosmetics

ActiveCN119112677AAntioxidant is goodGood soothing and anti-allergicCosmetic preparationsToilet preparationsPolymer scienceEthyl palmitate
The invention relates to a eutectic microcapsule wrapping technology and application thereof in cosmetics, and belongs to the technical field of cosmetic production. The wall material of the eutectic microcapsule inclusion comprises at least one of hydrogenated lecithin, caprylic / capric triglyceride, sucrose stearate, PEG-8 caprylic / capric glycerides, PEG-40 hydrogenated castor oil, soya bean lecithin, cyclodextrin, ethyl palmitate and troxerutin. The core material is prepared from at least one of salicylic acid, 4-butylresorcinol, glabridin, a kava extract, cortex magnoliae officinalis total phenols, ginseng oil, ganoderma lucidum spore oil, astaxanthin, coenzyme Q-10, a rosemary extract, ceramide and vitamin E. According to the invention, multiple eutectic coating can be formed, the consumption of the wall material can be reduced, the cost is saved, the wall material and the core material are matched for use, so that the excellent effects of permeation, oxidation resistance, soothing, allergy resistance and skin repair can be achieved, and the utilization rate of active substances is increased.
Owner:GUANGZHOU GAOTAI BIOTECHNOLOGY CO LTD