622 results about "Oxidative damage" patented technology

The invention relates to the field of biomedical materials, in particular to a novel composite collagen material for wound repair, and particularly relates to a preparation method of the novel composite collagen material containing 21-type recombinant humanized collagen (ColpepA1 21) and application of the novel composite collagen material in wound repair. The ColpepA1 21 is used for remarkably promoting key biological reactions in the wound healing process, including accelerating cell migration, enhancing the skin hydration state and barrier function and improving the stability and elasticity of the skin structure, a novel composite collagen material is developed, wound healing and cell regeneration can be effectively promoted, and oxidative damage can be relieved.

The invention discloses an application of soluble lignin as a synergist for ethanol fermentation and / or improvement of stress resistance of yeast under a fermentation environment stress condition, the soluble lignin is added into an ethanol fermentation system, and the problems of pH instability, oxidative damage, heavy metal inhibition and the like in ethanol fermentation can be synchronously solved; the survival rate of yeast and the yield of ethanol are remarkably improved, the process steps are simplified, the cost is reduced, the method is suitable for ethanol industrial production of agricultural and forestry wastes and other raw materials, and a green and practical technical path is provided for efficient utilization of all components of lignocellulose. In addition, the soluble lignin disclosed by the invention can also be recycled, can still keep a relatively high synergistic effect after being recycled for multiple times, and has a wide application prospect in the field of bioethanol fermentation.

The invention discloses a compound composition with a multi-target heart protection function as well as a preparation method and application of the compound composition. The composition is composed of a basic functional oil phase, a core antioxidant / anti-inflammatory phase, a myocardial nutrition and regulation phase and a bioavailability promotion phase in a synergistic manner, and is integrated into a composite cardiac oligopeptide and microencapsulated particle key component substance through a specific enzymolysis and microencapsulation embedding process system. The invention aims to solve the technical problems of single target spot, insufficient synergistic effect of all components, low bioavailability of active components and poor stability of the existing heart protection product, and provides a stable and easily-absorbed composite composition which can realize synergistic effect from multiple channels at the same time. Technical effect verification shows that under the condition of equal-dose sample feeding, the composition can remarkably improve the bioavailability of functional components and shows excellent myocardial cell oxidative damage resistance and myocardial ischemia improvement activity in cell and animal models, the effect is remarkably superior to that of independent use or simple physical mixing of all the components, and the composition is suitable for clinical application. And the substantial progress of synergistic interaction is proved. The composition can be used for developing various medicines, health foods and functional foods beneficial to heart health.

The invention relates to the technical field of health care product preparation, and particularly discloses an oyster peptide enzyme oral liquid capable of enhancing immunity and a preparation method thereof, the oyster peptide enzyme oral liquid comprises the following components: 20 parts of oyster peptide, 50 parts of plant enzyme liquid, 5 parts of honey, 2 parts of fructo-oligosaccharide, 2 parts of lemon juice and 100 parts of purified water; the oyster peptide enzyme oral liquid contains rich natural antioxidant ingredients including oyster peptide and plant enzyme liquid, the oyster peptide contains a large amount of sulfur-containing amino acid, and the ingredients can be used as antioxidants to reduce generation of free radicals and protect cells from oxidative damage; the plant enzyme is rich in natural antioxidant enzyme, can promote synthesis of antioxidant enzyme in vivo and remove free radicals in vivo so as to slow down senescence and diseases, the oyster peptide and the enzyme act together to improve the activity of catalase in vivo, and oxidative stress is reduced by removing superoxide anion free radicals.

The invention relates to preparation of high-stability mascarpone cheese and application of the mascarpone cheese in baking, and belongs to the technical field of cheese preparation. The glutamine transaminase is combined with a citric acid-sodium citrate system, so that the excessive denaturation of protein is reduced, and the texture and flavor of the cheese are improved. Trehalose and xanthan gum are added for locking water and resisting freezing, and an antioxidant is combined for use, so that the freeze-thaw stability and oxidation resistance of the cheese are improved, the cheese is protected from texture change and oxidative damage in the freezing and unfreezing processes, and excellent texture and flavor can still be kept after multiple times of circulation. Arabic gum is modified through octenyl succinic anhydride, amphipathy is obtained, whey separation is prevented, whey loss is reduced, and the cheese taste is improved.

The invention relates to a method for improving cadmium stress resistance of rice by using carbon quantum dots (CDs), which solves the technical problem that rice growth is affected due to the fact that rice is deeply poisoned by cadmium in the prior art by spraying the carbon quantum dots on leaf surfaces of the rice or irrigating the carbon quantum dots into root soil of the rice. CDs are used as a leaf surface resistance and control agent to treat cadmium-stressed rice, and it is found that on the premise that growth and development of the rice are not affected, CDs can improve the stress resistance of the rice by promoting photosynthesis of the rice and can stimulate a rice defense system to generate more antioxidant enzymes to cope with oxidative damage caused by Cd stress. Besides, CDs can also reduce the concentration of DTPA-Cd in soil and reduce accumulation of Cd on the overground part so as to further reduce the toxicity of Cd to rice, and meanwhile, the Cd content of the overground part of the rice is reduced so as to be beneficial to reducing accumulation of Cd in grains, so that CDs can be used as a leaf surface resistance and control agent to effectively relieve cadmium toxic rice, thereby promoting growth and development of the rice and improving the yield.

The present invention relates to the field of biomedical materials, particularly to a novel composite collagen material for wound repair, and more specifically to a method for preparing a novel composite collagen material comprising recombinant humanized collagen type 21 (ColpepA1 21) and its use in wound repair. The present invention utilizes ColpepA1 21 to significantly promote key biological reactions in the wound healing process, including accelerating cell migration, enhancing skin hydration and barrier function, and improving the stability and elasticity of skin structure. The resulting novel composite collagen material effectively promotes wound healing and cell regeneration, alleviating oxidative damage.

The invention relates to the field of modified milk, in particular to pasteurized modified milk with a lead ion emission reduction function and application of the pasteurized modified milk. The pasteurized modified milk provided by the invention contains lactobacillus mucus fermentation B44, wherein the preservation number of the lactobacillus mucus fermentation B44 is CGMCC (China General Microbiological Culture Collection Center) No.17321. Compared with a control sample and other strains, the lactobacillus mucilaginosus B44 in the pasteurized modified milk provided by the invention can remarkably reduce the lead content in intestinal content supernatant, and results of in-vivo experiments of rats show that the lactobacillus mucilaginosus B44 can remarkably reduce the blood lead concentration, the lead content in livers and the lead content in kidneys of drinking objects, so that the lactobacillus mucilaginosus B44 can be used for preparing the pasteurized modified milk. The discharge of lead in excrement can be increased, and liver oxidative damage caused by lead poisoning can be effectively relieved, so that the method can be applied to research on in-vivo emission reduction of lead.

The invention belongs to the field of corn disease prevention, relates to a novel small peptide, provides a small peptide NCRP246 and application thereof in improvement of corn southern leaf blight resistance, and provides feasibility for plant disease resistance by using non-classical peptides. A corn southern leaf blight resistance identification experiment proves that NCRP246 can significantly improve the resistance of corn to southern leaf blight, and further researches that the NCRP246 reduces oxidative damage of pathogenic bacteria infection of the southern leaf blight to the corn by reducing H2O2 accumulation so as to mediate the resistance of the corn to the southern leaf blight; the analysis from the molecular perspective proves that the NCRP246 can induce the expression of defense related genes.

The invention discloses a cold response PaIBH1 protein and application of a coding gene thereof in enhancing cold stress resistance of plants. The cold response PaIBH1 protein is a protein PaIBH1 with an amino acid sequence as shown in SEQ ID NO: 2. Experiments prove that the gene for coding the protein PaIBH1, namely the gene PaIBH1, is overexpressed in wild type arabidopsis thaliana, so that the cold resistance of the arabidopsis thaliana can be improved; the improvement of the cold resistance shows that after cold treatment, the fresh weight of the overground part is increased, the wilting rate is reduced, the leaf membrane damage and electrolyte leakage are reduced, the photosynthetic ability is improved, the membrane lipid peroxidation damage is relieved, the active oxygen scavenging ability is enhanced and / or the active oxygen accumulation in the plant body is reduced. Therefore, the protein PaIBH1 can improve the cold resistance of the plants. The method has a very wide application prospect in the aspect of cold-resistant genetic improvement of crops or pasture.

The present invention discloses a strain of Lactobacillus paracasei that simultaneously activates immune regulation and antioxidant pathways to alleviate vaginitis, belonging to the field of microbial technology. The present invention screened and obtained a strain of Lactobacillus paracasei CCFM1316, which has the effect of repairing related symptoms such as immune disorders and oxidative damage caused by vaginitis, specifically embodied in: reducing cellular NF-κB mRNA expression and cell supernatant IL-1β content, improving mouse vaginal immune response, enhancing mouse vaginal antioxidant capacity, improving mouse vaginal pathological manifestations and reducing pathogenic bacteria load. It reduces the mouse vaginal Gardnerella load and improves mouse vaginal pathological manifestations; therefore, Lactobacillus paracasei CCFM1316 has great application prospects in products that improve and repair immune disorders and oxidative damage problems caused by vaginitis.

The invention relates to a plant lactobacillus with effects of dispelling effects of alcohol, protecting the liver and restoring consciousness and application of the plant lactobacillus. The plant lactobacillus is a plant lactobacillus BGI-J9 strain, and the preservation number of the plant lactobacillus is CCTCC NO: M 20242630. The invention further discloses a preparation method of the plant lactobacillus with the effects of dispelling effects of alcohol, protecting the liver and restoring consciousness and application of the plant lactobacillus with the effects of dispelling effects of alcohol, protecting the liver and restoring consciousness. The strain has excellent tolerance to gastric acid, intestinal juice and cholate in a gastrointestinal tract system, can survive in the gastrointestinal tract, and provides a basis for continuously playing a probiotic effect; the compound has excellent inhibition capability on common intestinal pathogens; free radicals can be removed, and oxidative damage to the body is reduced; good alcohol metabolism enzyme synthesis capability and alcohol metabolism promoting potential are realized; the strain also has an excellent improvement effect on alcohol-damaged mice, specifically, the metabolism of ethanol and acetaldehyde in a body is accelerated, the occurrence time of drunkenness is obviously delayed, and the sobering time is shortened; intestinal injury and systemic inflammation caused by alcohol are improved; liver oxidative stress caused by alcohol is improved, and the occurrence and development process of alcoholic fatty liver is delayed; and cognitive function impairment caused by alcohol is improved.

The invention discloses a method for improving in-vivo and in-vitro antioxidant activity of pomegranate peel polyphenol extract through combined enzymolysis of tannase and beta-glucosidase, and relates to the technical field of food science and biology. The pomegranate peel polyphenol extract provided by the invention is obtained from pomegranate peel powder through solvent extraction. According to the present invention, tannase and beta-glucosidase are adopted to perform single or combined enzymolysis on the pomegranate peel polyphenol extract, and the determination on the in vitro antioxidant activity of the pomegranate peel polyphenol extract shows that the antioxidant activities of DPPH and ABTS after the combined enzymolysis are improved by 29.84% and 29.30% compared with the antioxidant activities of the untreated polyphenol extract; the UPLC-ESI-QTOF-MS is used for identifying and analyzing the components of the enzymatic hydrolysate, the content of macromolecular ellagic tannin is obviously reduced, and the content of micromolecular ellagic acid and gallic acid is increased. The enzymolysis polyphenol is applied to D-galactose induced oxidative stress mice, and the result shows that the oxidative damage relieving effect of the enzymolysis polyphenol on the mice is better than that of untreated polyphenol.

The present disclosure provides for improved compositions of ionizable lipid nanoparticles for the delivery of therapeutic nucleic acids to cells. Anionic phospholipids, including phosphatidylserine and phosphatidylglycerol are included in the lipid nanoparticles to increase the transfection efficiency in human dendritic cells. The further incorporation of mono-unsaturated alkyl chain analogs in dimethylaminopropyl-dioxolane or heterocyclic ketal ionizable lipids in the formulation demonstrated high levels of transfection in human dendritic cells, compared to other ionizable lipids in the same family, and demonstrated good stability to oxidative damage. Finally, the use of an ammonium salt of phosphatidylserine allows for the efficient production of PS-targeted LNPs.

The invention belongs to the technical field of bioactive peptides, and particularly relates to an antioxidant polypeptide as well as a preparation method and application thereof. The antioxidant polypeptide provided by the invention contains at least one of LMGPR, GFDGD, FGFDGDF and GHNGLDGL. The antioxidant polypeptide has better oxidation resistance, can relieve oxidative damage and inflammation, plays a role in protecting oxidative stress cells, is non-toxic to cells, and can be used as an active component of an antioxidant product. The four peptide fragments also have a synergistic effect in the anti-oxidation aspect, and an excellent anti-oxidation effect can be generated by compounding use of the four peptide fragments.

The invention relates to the technical field of bioactive peptides, and discloses a walnut peptide with a neuroprotection function and a preparation method and application thereof, and predicts that a batch of small molecular walnut peptides have the neuroprotection function through enzymolysis of natural walnut protein, molecular weight screening and molecular docking. Experiments prove that the walnut peptide disclosed by the invention has a nerve protection function: the cell activity of nerve cells is improved, and the walnut peptide plays a role in preventing neurodegenerative diseases and other nerve-related diseases; the toxic effect of oxidative damage on nerve cells is relieved, nerve cell apoptosis is inhibited, the cell viability of the nerve cells is improved, and the function of treating nerve injury related diseases is achieved; the compound can be used for improving the activity of nerve cells, relieving oxidative damage of the nerve cells, adjusting the protein level of nerve damage related pathways, preparing related drugs for reducing blood pressure or resisting senile dementia or tumors and the like, and has a wide application prospect.

The invention relates to a plant composition as well as a preparation method and application thereof, and belongs to the technical field of health food. The plant composition is prepared from the following components in parts by mass: 5 to 30 parts of fructus gardeniae, 5 to 30 parts of fructus rubi and 5 to 30 parts of fructus lycii. The plant composition can effectively relieve liver oxidative stress and inflammation conditions, relieve and / or improve alcoholic liver injury, protect liver cells from oxidative injury, assist a body in resisting oxygen free radical invasion and maintain the health state of the body, does not affect the blood sugar level, and has the advantages of being reasonable in compatibility, good in quality, safe and effective.

The invention provides a chitosan-iron nanoparticle leaf surface resistance and control agent as well as a preparation method and application thereof, and belongs to the technical field of reduction of heavy metal pollution of crops. The preparation method comprises the following steps: dissolving chitosan in an organic solvent to obtain a chitosan solution, mixing the chitosan solution with ferrous sulfate, adding a sodium tripolyphosphate solution for crosslinking and stirring to obtain a solution containing precipitates, centrifuging, and collecting the precipitates to obtain the chitosan / ferrous sulfate composite material. The TPP and amino groups of the chitosan form ionic crosslinking through triphosphate groups, and Fe < 2 + > is successfully loaded on the surfaces of the chitosan nanoparticles. By complexing chitosan and Fe < 2 + >, the crystallinity of the material is reduced, and the adsorption activity of the amorphous structure is enhanced. Pot experiments show that by spraying the chitosan-iron nanoparticle leaf surface resistance and control agent on leaf surfaces, heavy metals of crops can be remarkably reduced, the antioxidant enzyme activity of plant tissues is improved, active oxygen is effectively removed, oxidative damage is relieved, and therefore plant growth is promoted, and the toxic effect of heavy metal stress on the crops is relieved.

The invention discloses an anti-aging composition containing PQQ and a preparation method of the anti-aging composition, and belongs to the field of medicines or health food, the anti-aging composition comprises PQQ, an antioxidant, collagen, hyaluronic acid and a plant extract, and the content of PQQ is 0.1-5%; 1%-10% of collagen; 0.05%-2% of hyaluronic acid; the antioxidant comprises the following components in percentage by weight: 0.5%-5% of vitamin C, 0.1%-3% of alpha-tocopherol and 0.05%-2% of beta-carotene; the composition contains PQQ and various antioxidants such as vitamin C, alpha-tocopherol, beta-carotene, coenzyme Q10 and glutathione, and the components have a synergistic effect, so that free radicals can be effectively removed, oxidative damage can be reduced, and cell aging can be delayed; most of the components in the composition are natural substances or are widely applied to the fields of food and health care products, the safety is high, and the quality and safety of the product can be ensured through the steps of strict preparation process control, accurate component dissolving method, pH value adjustment, filtration and the like.

A circadian rhythm-based time-sharing repair formula and use thereof. A day composition focuses on anti-oxidation, stress resistance and energy metabolism to resist oxidative damage and enhance day vitality and provide long-lasting antioxidation protection. A night composition focuses on DNA repair, anti-inflammation and nerve relaxation to promote cell regeneration and repair and continuously support night repair. The composition of the day composition and the night composition designed according to the circadian rhythm of human metabolism causes the corresponding activities to take effect at the best time, and components are designed to cooperate with each other according to different physiological needs during the day / night, which can greatly improve the anti-aging effect.

The invention discloses a plant lactobacillus with light aging resistance and an application thereof. The preservation number of the plant lactobacillus cj001 disclosed by the invention is CGMCC (China General Microbiological Culture Collection Center) No.35419. The fermentation supernatant of the plant lactobacillus cj001 shows good anti-aging activity and in-vitro antioxidant activity, and the growth ability of HaCaT cells is promoted. After the combined fermentation product of the plant lactobacillus cj001 and the lactobacillus paracasei Grx701 is subjected to ultraviolet radiation, the proliferation of HaCaT cells can be promoted, the endogenous antioxidant capacity of human skin cells can be enhanced, the photooxidation damage can be effectively relieved, and the combined fermentation product has a wide application value in the field of preparation of products with antioxidant, anti-aging, anti-ultraviolet damage, anti-photoaging and the like.

The invention belongs to the field of biological medicines, and discloses a stress-induced mesenchymal stem cell extract and a preparation method and application thereof.The preparation method comprises the steps that S1, mesenchymal stem cells are cultured under the high-temperature condition, swelling and cracking are conducted on the mesenchymal stem cells, or supernate obtained after culture of the mesenchymal stem cells is taken and filtered, and filtrate is obtained; the temperature of the high temperature ranges from 37.0 DEG C to 42.0 DEG C; s2, purifying the mesenchymal stem cell extract by adopting a molecular sieve exclusion chromatography method or a reverse chromatography method. Specific high-temperature stimulation is adopted to induce the mesenchymal stem cells, a purification method is combined, protein expression is promoted, the purity of the mesenchymal stem cell extract is improved, the prepared and obtained purified Alibitumen is used in a cell oxidative damage model, and the cell oxidative damage rate is increased. It is found that all the Aribitua derived from high-temperature stress culture has high oxidative damage repairing capacity.

The invention belongs to the technical field of semiconductors, and particularly relates to a polishing composition and a preparation method and application thereof. The polishing composition comprises grinding particles, an oxidizing agent, an organic dispersing agent, an inorganic dispersing agent, a pH buffering agent, a pH adjusting agent and water. Wherein the oxidizing agent comprises permanganate, the organic dispersing agent forms an organic coating layer on the surface of the grinding particles, and the inorganic dispersing agent forms an inorganic coating layer on the surface of the organic coating layer. Through the steric hindrance of the organic dispersing agent and the static stable synergistic effect of the inorganic dispersing agent, the grinding particles obtain a good dispersing effect. Meanwhile, the outer surface of the organic coating layer is coated with the inorganic coating layer, so that oxidative damage of a strong oxidant to organic dispersant molecules of the organic coating layer can be prevented, and the dispersion stability and the polishing stability of the polishing composition are improved. Therefore, the polishing composition containing the grinding particles can continuously obtain low-defect and low-roughness surfaces when processing third-generation semiconductor materials.

The invention discloses a plant source leaf surface resistance and control agent for efficiently reducing the cadmium content of wheat and a preparation method thereof. According to the invention, S-allyl-L-cysteine is used as an important component of the foliar blocking and controlling agent, so that the bioavailability of cadmium ions is effectively reduced, and the absorption and transport of cadmium in plants are reduced, thereby reducing the cadmium content in wheat grains. Meanwhile, S-allyl-L-cysteine has relatively strong antioxidant capacity, so that free radicals in the plant body can be removed, and cells are protected from oxidative damage. As a plant growth regulator, S-allyl-L-cysteine can improve nutrient absorption and utilization of plants and promote photosynthesis and energy metabolism of the plants, so that the yield and quality of wheat are improved. The S-allyl-L-cysteine can activate a defense mechanism in a plant body, enhance the resistance of the plant to environmental stress, including the resistance to heavy metal pollution, and improve the overall health and yield of wheat.

The invention discloses application of spermidine in preparation of an agent for resisting mitochondrial oxidative damage and copper death damage, and relates to the technical field of biology. The invention provides an application of spermidine in preparing an agent for resisting mitochondrial oxidative damage and copper death damage, and further provides an application of spermidine in inhibiting copper death induced by copper sulfate and relieving iron-sulfur cluster protein loss and ester acylation protein aggregation induced by copper accumulation. The spermidine can obviously relieve cell viability decline induced by copper sulfate, reverse ROS and MDA level increase and mitochondrial membrane potential decline induced by copper sulfate and relieve iron-sulfur cluster protein loss and ester acylation protein aggregation induced by copper accumulation, and has obvious effects of inhibiting mitochondrial oxidative damage and copper death. The invention provides a method for effectively relieving copper death of ovarian granular cells, and solves the problem that the existing antioxidant and cytoprotective agent for resisting mitochondrial oxidative damage generate side effects in the use process.

The invention discloses an American ginseng fermentation extract and application thereof, and belongs to the technical field of traditional Chinese medicine fermentation and cosmetics. According to the method, American ginseng is fermented by adopting bacillus mojavensis, and operation and parameters of links such as preparation, fermentation, purification and freeze drying of a fermentation substrate are regulated and controlled, so that various enzymes generated in the metabolic process of the bacillus mojavensis are used for converting and modifying various active ingredients in the American ginseng, and the biological activity of the American ginseng is enhanced. Compared with unfermented American ginseng, the American ginseng fermentation extract prepared by the preparation method disclosed by the invention has the advantages that the soluble solids are obviously increased, the contents of active substances such as saponin and polyphenol are also obviously increased, the antioxidant activity is also obviously improved, and the American ginseng fermentation extract has an obvious improvement effect on oxidative damage cells, effectively improves the skin microenvironment and achieves the purpose of skin care; the important significance is realized on the development of anti-aging cosmetics.

The invention discloses a ganoderma lucidum lipid exosome containing a liver protection component and a preparation method and application thereof.The preparation method comprises the steps that the liver protection component is wrapped with a coarsely extracted ganoderma lucidum exosome, then the liver protection component is wrapped with lipidosome, and therefore a lipidosome-exosome-liver protection component three-layer structure is formed from outside to inside; in the three-layer structure, the outer layer liposome can protect the storage of the liver protection component and can improve the transmembrane transport efficiency, the middle layer exosome serves as a carrier and can reach a designated position to be released, and the inner layer contains the liver protection component and can improve the transmembrane transport efficiency. Cell cycle arrest can be prevented, antioxidant enzyme activity can be improved, cell membranes can be protected from oxidative damage, and redox steady state can be maintained to relieve cell aging. The prepared ganoderma lucidum lipid exosome containing the liver protection component realizes slow release synergy through a three-layer structure, and the action time of the active component is remarkably prolonged.

The invention relates to the technical field of microorganisms, in particular to lactobacillus paracasei DT33 and application of the lactobacillus paracasei DT33 in preparation of products with microplastic adsorption, removal and defecation promotion functions. The lactobacillus paracasei DT33 disclosed by the invention can be used for producing various SCFAs at high yield, has better acid-resistant and cholate-resistant capabilities and safety, and can be developed into edible probiotics; the strain has the function of promoting defecation, and can improve intestinal health and immune function; in addition, the strain can adsorb micro-plastics, accelerate discharge of the micro-plastics, reduce micro-plastic residues in intestinal tracts, reduce oxidative damage and inflammatory response caused by accumulation of the micro-plastics, and provide great benefits for intestinal health of human bodies and animals.

The invention discloses an algin composite membrane which is prepared by the following steps: adding 0.8-1.2 g of algin, 0.8-1.2 g of hydroxypropyl methyl cellulose, 0.8-1.2 mL of glycerol, 0.4-0.6 g of titanium dioxide and 0.8-1.2 g of polylysine into water, uniformly mixing, fixing the volume, putting into a container, drying, immersing into a CaCl2 solution for crosslinking treatment, and drying, thereby obtaining the algin composite membrane. The algin composite film can be used as or used for preparing a food preservative film. The algin composite film disclosed by the invention realizes good balance between strength and ductility, has good antioxidant capacity and remarkable antibacterial effect, and can effectively enhance the antioxidant defense capacity of the cape gooseberries, reduce oxidative damage, prolong the storage period and improve the fresh-keeping effect of the cape gooseberries. According to the method, the economic value of the sargassum is favorably improved, and powerful support is provided for sustainable development of the food industry.

The invention belongs to the technical field of skin care products, and particularly relates to a skin care composition as well as a preparation method and application thereof. The skin care composition provided by the invention is prepared from the following raw materials: a helichrysum palustris extract, a butterflybush flower extract and a chicory extract. The skin care composition can improve the oxidative damage resistance of the skin, reduce the damage of ultraviolet rays in the external environment to the skin, enhance the skin barrier, reduce the sensitive reaction of the skin, reduce the inflammatory reaction of the skin and promote the generation of collagen, so that the damaged skin is quickly repaired, and the repairing effect is remarkable. The skin care composition can be added and applied to various types of skin care products, and is moderate in cost, simple to prepare and suitable for industrial mass production.