42 results about "Desquamation" patented technology

The invention provides a composition for repairing a skin barrier as well as a preparation method and application thereof, and relates to the technical field of cosmetics. The invention discloses a composition for repairing a skin barrier. The composition comprises ceramide NP1, ceramide AP, ceramide EOP, asiaticoside and DNA sodium. The composition is used for repairing skin from related proteins such as endogenous and endogenous injury, inflammatory factor inhibition, light injury, skin cuticle barrier and the like, and can deeply resist inflammation, relieve and maintain stability in an endogenous and endogenous two-way manner, and repair the damaged skin barrier in a multi-level and multi-dimensional manner, so that the skin problems such as skin dryness, roughness, desquamation, redness and swelling, pruritus and the like are improved.

The invention relates to the field of cosmetics, in particular to a sialic acid composition with an acne removing effect, a preparation method of the sialic acid composition and cosmetics. The composition is prepared from 8%-20% of sialic acid, 10%-25% of ectoine, 5%-15% of a humectant, 0.1%-1% of a thickening agent, 0.05%-0.5% of a pH regulator and the balance of water. Cubilose acid can promote collagen synthesis, repair damaged skin barrier and reduce inflammatory response caused by external stimulation, and acne generation is inhibited from acne inducement; meanwhile, the sialic acid can inhibit release of proinflammatory factors such as TNF-alpha and IL-6 by adjusting a TLR receptor signal channel, red and swollen pox is relieved, and the generated pox is inhibited from the aspect of inhibiting inflammation; the sialic acid is non-irritant, and can slightly promote cutin renewal under high concentration, so that the problems of skin desquamation, sensitivity and the like caused by barrier injury can be effectively avoided. Ectoin is compounded, so that the Ectoin and sialic acid can generate a synergistic interaction effect.

The invention relates to a pharmaceutical composition, which is prepared from adapalene, benzoyl peroxide, a traditional Chinese medicine extract, an acrylamide and acryloyl dimethyl sodium taurate copolymer, a mixture of isohexadecane and polysorbate 80, docusate sodium, EDTA (Ethylene Diamine Tetraacetic Acid) disodium, glycerol, poloxamer 124, propylene glycol and water, the traditional Chinese medicine extract comprises moutan bark, salvia miltiorrhiza, radix rehmanniae recen, radix sophorae flavescentis, coptis chinensis, rheum officinale, scutellaria baicalensis, menthol and borneol. According to the pharmaceutical composition disclosed by the invention, the synergistic antibacterial and anti-keratosis curative effects of adapalene and benzoyl peroxide can be maintained, and meanwhile, the occurrence rate of local skin dryness, erythema, desquamation, burning heat sensation and contact dermatitis can be remarkably reduced.

This invention discloses a strain of Bifidobacterium animalis subspecies TRT-2A with allergy-relieving effects and its extracellular vesicle applications. The strain TRT-2A is deposited at the China Center for Type Culture Collection (CCTCC) on November 21, 2025, with accession number CCTCC NO:M 20252645. This strain is highly acid-resistant and exhibits good tolerance to artificial gastric and intestinal fluids. It effectively inhibits bacteria, particularly Streptococcus pyogenes, Streptococcus agalactiae, and / or Escherichia coli. Experimental results show that this strain can alleviate hormone-dependent dermatitis and effectively improve dermatitis symptoms such as erythema and desquamation. Furthermore, extracellular vesicles prepared using TRT-2A can effectively improve skin elasticity and reduce wrinkles. Therefore, the Bifidobacterium animalis subspecies TRT-2A of this invention has multiple functions and is worthy of further promotion and application.

This invention provides a novel application of IdeS, which is used to prepare products addressing photoaging of the skin. These products include skincare products and pharmaceuticals for the prevention and / or treatment of photoaging. The pharmaceuticals are in the form of ointments, and the skincare products are used as adjunct treatments for preventing and treating photoaging. IdeS treatment significantly improves the extensive erythema, wrinkles, desquamation, inflammation, and thickened stratum corneum observed in photoaging model mice. It has been developed as a novel biological therapeutic drug with strong pharmacological effects, few side effects, and avoidance of allergic reactions, thus providing a basis for the clinical treatment of photoaging and photodamage.

The invention relates to the technical field of light control, in particular to a skin visual detection control method based on a silicon substrate multi-primary-color LED lamp. According to the method, the original skin image is continuously acquired, the local window is divided, and the similarity of the structure direction field and the color gradient field of the local texture is combined, so that the high-resolution recognition of the skin texture state is realized, and the recognition precision of the facial detail abnormity is enhanced. By setting the fuzzy judgment interval and quantifying the membership degree, a multi-dimensional recognition system for different abnormal types such as color spots, redness and swelling, dry decrustation, acnes and comedos is established, and the sensitivity and adaptability of skin abnormality judgment are remarkably improved. In a color response interference identification process, an inter-class variance is introduced to calculate a response difference between a red channel and a yellow channel, so that the influence of a color overlapping region is effectively eliminated, and the effectiveness and independence of extracting a gray region are ensured. And further extracting an effective gray area in the non-interference area.

The present invention relates to human tissue kallikrein 7 (KLK7) selective inhibitor compounds, combinations including these compounds, process to obtain the referred compounds, and methods of using the same. The present invention belongs to the field of chemistry, pharmacology and medicine.

The invention relates to the field of skin sampling tools, and discloses an eczema patient skin lesion sampler which comprises a sampler body, a detection mechanism and a cutting mechanism are arranged in the sampler body, the detection mechanism is used for detecting the position and state of the skin lesion of a patient, and the cutting mechanism is used for cutting the skin lesion of the patient. The cutting mechanism is used for sampling a skin lesion area of a patient, the sampler body comprises a protective shell, a handle shell is arranged at the bottom of the protective shell, the protective shell is connected with the handle shell, the cutting mechanism comprises a cutting bin, and a plurality of baffles are arranged in the cutting bin. According to the invention, the detection mechanism is used for accurately identifying the state of a skin lesion part, and differential cooperation of multiple groups of cutting knives in the cutting mechanism is combined, so that corresponding sampling is realized for different states such as acute exudation, subacute and chronic desquamation and crust, and the problems of slow sampling and influence on a test result caused by eczema state difference in the prior art are solved; and the sampling efficiency and accuracy are improved.

The present application relates to the technical field of food peeling, and particularly relates to a skin removing device and method for production of dendrobium officinale, which comprises a base, a peeling assembly is installed in the base, the peeling assembly comprises a peeling shell body arranged above the base, a skin screening barrel is fixedly connected in the peeling shell body, a feeding pipe is communicated to one side of the skin screening barrel, a material taking opening is arranged on the side wall of the peeling shell body, the peeling shell body is controlled to rotate through a driving motor, a heating pipe is communicated in the peeling shell body, a connecting opening is communicated to the side wall of the heating pipe, and the connecting opening is used for being connected with an external heating air pump; a swing assembly is arranged on one side of the heating pipe, the swing assembly comprises a rectangular cylinder fixedly connected to one side of the heating pipe, a swing block is arranged on the side wall of the rectangular cylinder, an air outlet is arranged in the swing block, and the air outlet is communicated with the connecting opening. The present application solves the problems of the prior art that the raw materials are easily damaged and the separation effect is poor, and the present application cannot be adapted to industrialized continuous production.

The invention belongs to the technical field of cosmetics, and discloses a skin-soothing barrier composition capable of being used for children suffering from eczema and application of the skin-soothing barrier composition. The skin-soothing barrier composition is prepared from the following components in parts by mass: 0.05 to 4 parts of fructus schisandrae chinensis extract, 0.1 to 3 parts of tetrahydromethylpyrimidine carboxylic acid, 0.05 to 3 parts of lactobacillus / algae extract fermentation product, 0.05 to 3 parts of glycosylglycerol and 0.3 to 5 parts of capparis spinosa fruit extract. Through the combination of the specific components, a good synergistic effect is generated among the components, the effects of resisting inflammation, relieving, moisturizing, locking water, resisting oxidation and the like are effectively improved, on one hand, oxidative stress injury is relieved, and red-sensitive scorching heat is relieved; on the other hand, dry desquamation is improved by repairing keratinocytes and reinforcing a barrier; therefore, a more comprehensive improvement effect is achieved on symptoms such as repeated attack of eczema, itching and discomfort, dryness and desquamation, red sensitivity and scorching heat of children and the like.

The present invention provides a method and a pharmaceutical composition for treatment of skin diseases associated with accelerated comeodesmosomes degradation and / or weaker cell-cell adhesion, such as a peeling skin syndrome, Netherton syndrome, and atopic dermatitis.

The application discloses a use of a topical preparation containing crocetin or a pharmaceutically acceptable salt thereof. The topical preparation developed in the application is used for treating cheilitis simplex actinica caused by chemotherapy, is convenient to use, has few toxic and side effects, and can effectively relieve symptoms such as cheilitis simplex actinica, lip crack, desquamation, erosion and scabbing caused by chemotherapy. The application also expands the application field of crocetin drugs, and finds a new use of crocetin and the salt thereof, which can be prepared into a topical preparation for preventing / treating skin inflammation or skin damage, especially for preventing / treating cheilitis simplex actinica caused by chemotherapy and skin damage caused by oxidative stress, and has better effects. When the crocetin and the salt thereof are used in combination with chlorogenic acid, they have better therapeutic effects. The crocetin and the salt thereof have higher stability when prepared into the topical preparation, are easier to obtain high-purity products, and are more suitable for pharmaceutical development.

There is a need to have novel active agents that act against excessive desquamation of the skin or the scalp, in order to limit and / or prevent desquamation and thereby contribute to skin comfort.SOLUTION: The present invention relates to an alcoholic extract of the peel of Citrus aurantium, to a cosmetic composition comprising such an extract, in particular having a preventive effect on skin desquamation, and to a process for the preparation thereof.SELECTED DRAWING: Figure 1

The invention relates to the technical field of control, in particular to a ginger processing production line control method. Analyzing by combining historical ginger peeling records and preset skin removal indexes to obtain a plurality of expected residual skin proportions of the plurality of peeling stages; initial peeling parameters are set based on the ginger attribute characteristics of the to-be-peeled ginger, and peeling equipment is controlled to execute peeling operation in a first peeling stage according to the initial peeling parameters; performing peeling state identification on the first peeled ginger image to obtain a first predicted residual peel proportion; performing peeling parameter optimization according to the ginger attribute characteristics and the first predicted residual peel proportion, and outputting a second optimal peeling parameter; and according to a second optimal peeling parameter, performing peeling operation of a second peeling stage, performing iterative feedback control, and stopping the fresh ginger peeling operation until the fresh ginger peeling period is completed or the current predicted residual skin proportion is smaller than or equal to a preset skin removal index. The ginger peeling precision, efficiency and product quality stability are obviously improved.

The utility model provides a blood disease chemotherapy patient skin care device which comprises a care device bottom plate, a connecting plate is fixedly arranged on one side of the top end of the care device bottom plate, a control handle is installed at the top end of the connecting plate, the control handle is in an L shape and can be conveniently held by medical staff, and a heat dissipation plate is fixedly arranged at one end of the care device bottom plate. According to the scheme, the medicine spraying plate is controlled to be started by pressing the control button, at the moment, the medicine spraying plate is started, the atomization spray head is turned on and turned off, and nursing liquid medicine in the storage disinfection tank is atomized outwards through the atomization spray head and applied to the positions, where symptoms occur, such as swelling, itching, dryness, desquamation and even ulceration, of the skin surface of a patient; and the skin care work of medical personnel is facilitated.

The invention relates to the technical field of cosmetics, in particular to application of mogroside V in preparation of skin barrier repair cosmetics, the mogroside V serves as an active ingredient, the purity of the mogroside V is not lower than 30%, and the mogroside V can be prepared into various cosmetic dosage forms such as toning lotion, facial masks and essence cream. The mogroside V has no significant toxicity to keratinocytes, can accelerate skin barrier repair by promoting cell migration, has significant antioxidant activity, and can scavenge free radicals, reduce oxidative stress injury and realize synergistic effects of barrier repair and oxidation resistance and aging resistance. Besides, mogroside V is a natural water-soluble component, can be stably dispersed in a water-based formula without a solubilizer, is free of thick and sticky feeling during use, and solves the problem of skin feeling pain points of traditional repairing components. The barrier damage problems of dry skin, redness, desquamation and the like can be improved in a targeted manner, and the application prospect is wide.

The present invention provides a method of preventing or treating inflammatory skin diseases by administering a composition comprising at least one milk-derived protein. The invention also relates to a method for moisturizing dry skin, softening skin, reducing skin itch, reducing skin desquamation, reducing skin redness, reducing rough skin, reducing skin swelling, reducing skin dehiscence, renewing skin cells, protecting hand skin or any combination thereof.

The invention relates to the related technical field of sub-health conditioning cabins, in particular to a sub-health conditioning cabin with infrared induction safety protection, which comprises a sub-health conditioning cabin, a built-in infrared temperature sensor monitoring cabin, a platform and an infrared induction assembly. The built-in atomization nozzles are distributed and mounted on the two sides of the built-in infrared temperature sensor monitoring cabin through the mounting plates, a medicament and a water source are injected into the sub-health conditioning cabin and the built-in infrared temperature sensor monitoring cabin through the connecting ends and the water pipes, and then spraying is performed through the built-in atomization nozzles; the water replenishing device has a water replenishing effect on the skin of a user, the situation that when the user is exposed to infrared irradiation for a long time, skin moisture evaporation is accelerated is avoided, water can be replenished to the skin in time, burning is prevented, skin dryness, rough decrustation and the like are prevented, and medicament atomization treatment and conditioning are further facilitated.

The application discloses a peanut wet red skin removing machine and belongs to the technical field of agricultural processing machinery. The peanut wet red skin removing machine comprises a rack, a red skin removing device, a pressing device, a skin cutting device, an extruding device, a skin cleaning device, a flying preventing device, a feeding port, a discharging port, a transmission device and a power device which are arranged on the rack. The red skin removing device comprises a plurality of red skin removing wheels which are arranged side by side and side plates which are arranged on the two sides of the red skin removing wheels. A feeding port and a discharging port are respectively arranged on one side plate. A feeding channel and a discharging channel which are communicated with the feeding port and the discharging port respectively extend into the red skin removing wheels. The pressing device, the flying preventing device and the skin cutting device are arranged in the inside of the red skin removing wheels in sequence in the clockwise direction. The skin cutting device is arranged at the uppermost position. The extruding device is arranged on the outside of the red skin removing wheels and is located below the skin cutting device. The skin cleaning device is arranged below the extruding device. The inside gap of the red skin removing wheel is larger than the outside gap. The peanut wet red skin removing machine can improve the red skin removing and cleaning rate of peanuts, reduce the breakage rate, remove the red skin of different varieties of peanuts and improve the universality of the red skin removing machine.

The invention provides a compound lotion suitable for dissolving traditional Chinese medicines as well as a preparation method and application thereof, and relates to the technical field of daily chemical products. The compound washing agent is composed of a specific content of a surfactant system, a nonionic solubilizer and a cationic conditioner. Wherein the mass ratio of the cocamidopropyl betaine to the sodium laureth sulfate to the sodium lauroyl sarcosine is (2.0 to 2.5) to (8.0 to 9.0) to (2.8 to 3.2). According to the compound lotion obtained by synergistically compounding the surfactant system, the nonionic solubilizer and the cationic conditioner, on one hand, the compound lotion can be independently applied to effectively relieve discomfort such as scalp greasiness, itching and desquamation; on the other hand, the compound lotion has better compatibility and solubility for the traditional Chinese medicine particles, and on the premise of high drug loading capacity of the traditional Chinese medicine particles, the shampoo is stable in character and good in washing feeling, and the preparation requirements of the traditional Chinese medicine particle shampoo can be fully met.

This invention belongs to the field of pharmaceutical technology and discloses a tribulus terrestris saponin gel formulation for repairing acute photodamage to the skin, its preparation method, and its application. The tribulus terrestris saponin gel formulation comprises a therapeutically effective amount of tribulus terrestris saponin, a gel matrix, and a transdermal absorption enhancing system. The transdermal absorption enhancing system consists of a pH adjuster and a chemical penetration enhancer, wherein the pH value of the gel formulation is adjusted to 5.8–6.5. The preparation method includes steps such as blank gel preparation, drug and penetration enhancer solution preparation, mixing to form a gel, pH adjustment, and volume fixation. This formulation, through precise pH matching and synergistic application of an azone-ethanol penetration enhancing system, significantly improves the transdermal penetration efficiency and skin retention of tribulus terrestris saponin, improves symptoms such as erythema and desquamation caused by acute photodamage to the skin, exhibits high safety, demonstrates more sustained drug release behavior, and thus achieves superior cumulative concentration and long-lasting repair effect at the site of acute photodamage to the skin.

The invention aims at providing a foot nursing device for endocrine diseases, and relates to the technical field of medical instruments, a supporting plate, a collecting basin and a massage frame are arranged on a base, and a sprayer is arranged on the collecting basin; during use, the legs of a patient are supported through the supporting plate, the massage frame is controlled to slide to enable the fixing plate to be tightly attached to the soles of the patient, the rotating plate is rotated to cover the instep, the soles, the instep and the legs supported by the supporting plate can be massaged through the massager, and blood circulation is promoted; the foot of a patient is covered with the claw-shaped structure at one end of the spraying rod of the sprayer, spraying and moisturizing are carried out on the foot of the patient, collection is carried out through the collecting basin, the skin of the foot is kept moist, dryness and desquamation are prevented, and the risk of skin chap is reduced.

The invention belongs to the technical field of biological medicines, and relates to a dried orange peel polysaccharide, a preparation method thereof and an application of the dried orange peel polysaccharide in preparation of psoriasis treatment drugs, the monosaccharide in the dried orange peel polysaccharide comprises rhamnose, arabinose, galactose, glucose and galacturonic acid according to a molar percentage ratio of (5-6): (24-27): (10-15): (7-10): (45-50). Compared with the prior art, the pericarpium citri reticulatae polysaccharide prepared by the invention has the advantages of being good in safety, high in anti-inflammatory activity, capable of effectively improving the oxidative stress state of cells, remarkably reducing epidermis aggregates, relieving excessive proliferation of epidermis, effectively relieving desquamation and erythema symptoms of skin lesions of psoriasis and the like, and can be used for preparing psoriasis treatment medicines; the treatment scheme of psoriasis is expanded, and wide application prospects and important clinical significance are achieved.

The invention discloses a decoction preparation method of a traditional Chinese medicine composition of abelmoschus manihot medicated bath soap, and relates to the technical field of traditional Chinese medicine external preparations. Comprising the following steps: (1) raw material compatibility and pretreatment: taking 10-25 parts by mass of abelmoschus manihot, 5-15 parts by mass of tobacco leaf stalks, 8-20 parts by mass of cacumen biotae, 5-15 parts by mass of saponin, 8-20 parts by mass of senecio scandens, 5-15 parts by mass of polygonum multiflorum, 5-15 parts by mass of angelica sinensis, 5-15 parts by mass of folium mori, 5-15 parts by mass of cortex dictamni, 5-15 parts by mass of radix sophorae flavescentis and 10-25 parts by mass of sodium carbonate. The adjuvant cacumen biotae is capable of removing dandruff and growing hair, and the conductant borneol is transdermal and guides channels; a plurality of medicinal materials have a synergistic effect and have a treatment effect on inflammation, pruritus, desquamation and other links of skin diseases; a superfine grinding technology is adopted, so that the dissolution rate of effective components is greatly improved; the extraction efficiency is ensured and the loss of volatile components is avoided by adopting a segmented boiling process; a three-stage filtering system ensures the purity and fineness of the product; the traditional Chinese medicines are combined with the modern soap agent, so that the soap has dual functions of cleaning and treatment.

The present disclosure relates to a topical skin care composition comprising colloidal oatmeal in combination with a Vincetoxicum officinale extract and / or a Populas alba extract. The present disclosure further relates to methods of treating symptoms of itch, redness, flaking, dryness, and / or roughness of the skin, scalp, and / or mucous membrane using such topical skin care compositions.

To provide deep skin cell regeneration without undesirable side effects such as desquamation, dry skin, itching, and erythema. [Solution] A composition is provided that combines oxygenated water with other components. This composition is generally intended to assist in the treatment of damaged skin tissue and to penetrate transdermally through the user's skin to the dermis. More specifically, the skin tissue regeneration composition may contain 80-95% by mass of oxygenated water and collagen in a concentration of more than 0% by mass and 5% by mass or less. The skin tissue regeneration composition may also contain 80-95% by mass of oxygenated water and elastin in a concentration of more than 0% by mass and 5% by mass or less. The use of the composition for the treatment of damaged skin tissue is also provided.

The invention discloses a traditional Chinese medicine composition for relieving head sebum overflow, pruritus and desquamation as well as a preparation and application of the traditional Chinese medicine composition. The composition is prepared from garden balsam stem, Chinese honey locust, cacumen biotae, dictamnus dasycarpus, althaea officinalis and radix sophorae flavescentis in parts by weight, and has the effects of dispelling wind, eliminating dampness, removing turbidity, removing fat, clearing heat, relieving itching and resisting bacteria on the basis of monarch, minister, assistant and guide compatibility of the traditional Chinese medicine'degreasing water aqua 'theory. The preparation comprises ointment, oral traditional Chinese medicine liquid, traditional Chinese medicine capsules and the like, and the ointment contains traditional Chinese medicine extract, a conditioner, a chelating agent and other auxiliary materials and is prepared through the processes of decoction, emulsification and the like. Clinical research shows that after 22 subjects use the ointment for 4 weeks, the grade of dandruff, greasiness, pruritus and alopecia is obviously reduced (Plt; 0.01), and the safety is good. The shampoo is scientific in formula, mild and low in irritation, can effectively improve multiple symptoms of scalp, and has quick-acting and long-acting effects.

The invention relates to a skin-nourishing source herbal maintenance liquid which comprises the following components in percentage by weight: 5-8% of ginsenoside; 25-30% of a pine needle extract; 10-13% of long-leaf pine oil; 1-5% of pinus densiflora leaf extract; 5-9% of cedar seed oil; 1-3% of cedrol; a proper amount of a pH regulator; and the balance of water. According to the skin-nourishing source herbal nourishing liquid, medicinal components are added into a formula of the liquid shampoo to prepare new liquid shampoo, and the problems that existing liquid shampoo is generally formed by mixing chemicals and has irritation or side effects on skin, and various skin problems such as dry skin, desquamation and itching can be caused when the skin is cleaned frequently can be solved; according to the present invention, the components are relatively simple, the decontamination effect is good, the pH value of the shampoo is controlled so as to make the shampoo closer to the pH value of the human skin, and the situation that the natural grease and other natural conditioning and moisturizing components of the skin are removed due to the frequent use of the shampoo in the non-pH range to clean the skin can be avoided.

The application discloses a kind of external use herbal essence with improving skin itching, which is composed of Tripterygium wilfordii Hook.f., Selaginella tamariscina, Senecio scandens Buchen, Viburnum dilatatum, water wong root and chestnut shell.The present prescription combines wind-heat, damp-heat and blood-heat, and has the effects of clearing heat and cooling blood, dispelling wind and relieving itching.It has achieved good effects in treating patients with skin itching, especially in treating peeling, dandruff and epidermal crack caused by dry skin after skin itching.The present application not only solves the problem of skin itching, but also makes the skin smooth and moisturized after treatment, and solves the problem of dry skin.Compared with western medicine, the present application has no side effects, fast curative effect, low cost and convenient use.

The invention discloses a hair drier with a liquid medicine auxiliary physical therapy function, and belongs to the technical field of hair driers, the hair drier comprises a control handle, and a plurality of control buttons are arranged on the control handle. During working, the motor drives the impeller to generate airflow, the heat conduction cylinder heats air through the heating wire, the micro liquid pump can pump liquid medicine and convey the liquid medicine to the atomization nozzle to form medicine mist in the process, the medicine mist is heated by hot air and then is wrapped by high-speed airflow to be conveyed to the scalp from the air outlet, and silver ions and zinc ions in the liquid medicine can inhibit reproduction of pathogenic bacteria; potassium ions can regulate scalp osmotic pressure and assist in maintaining moisture balance of cuticle, magnesium ions can promote local blood circulation and improve the absorption effect of liquid medicine, then selenium ions and panthenol are matched to relieve dry scalp desquamation, use is convenient, additional physical therapy equipment does not need to be used, and the cost is low. Therefore, the purpose of physiotherapy of the head skin is achieved cooperatively, and the comprehensive efficiency and sustainability of scalp health management are improved.