68 results about "Desquamation" patented technology

The invention discloses a barrier repair composition applicable to dry sensitive skin and application thereof. The composition comprises a golden camellia extract, a loquat leaf extract, an alfalfa extract and hydrolyzed royal jelly protein. According to the barrier repairing composition applicable to the dry sensitive skin, disclosed by the invention, through reasonable matching and synergistic interaction of all the components, a better skin barrier repairing effect can be achieved, so that the problems of dry and tight skin, desquamation, erythema, itching, dull luster, redness, burning heat sensation, pricking pain and the like of the dry sensitive skin are fundamentally solved.

The invention provides coconut oil essence hand cream and a preparation method thereof. The hand cream is prepared from the following raw materials in parts by weight: 18 to 24 parts of coconut oil essence, 12 to 15 parts of compound tremella extract, 3 to 6 parts of fig fruit extract, 7 to 10 parts of grape seed oil, 6 to 9 parts of olive fruit oil, 4 to 7 parts of squalane, 5 to 8 parts of fucoidin, 3 to 6 parts of galactooligosaccharide, 2 to 4 parts of dipotassium glycyrrhizinate, 10 to 14 parts of propylene glycol, 12 to 15 parts of glycerol, 0.01 to 0.05 part of preservative, 10 to 14 parts of sucrose fatty acid ester, 13 to 17 parts of sorbitan olivate, 0.2 to 0.6 part of essence and 140 to 180 parts of water. Through the mutual synergistic effect of the raw materials such as the coconut oil essence, the composite tremella extract, the fig extract, the grape seed oil, the olive fruit oil, the squalane, the fucoidin and the galactooligosaccharide, moisture of hand skin can be effectively locked, a protective layer is formed on the surface layer of the skin, loss of moisture of the hand skin is reduced, and the hand cream has a good hand moisturizing effect. Therefore, the hand skin is kept in a moisturized state, and the problems of skin dryness, desquamation, cracking and the like are effectively reduced.

The invention provides a composition for repairing a skin barrier as well as a preparation method and application thereof, and relates to the technical field of cosmetics. The invention discloses a composition for repairing a skin barrier. The composition comprises ceramide NP1, ceramide AP, ceramide EOP, asiaticoside and DNA sodium. The composition is used for repairing skin from related proteins such as endogenous and endogenous injury, inflammatory factor inhibition, light injury, skin cuticle barrier and the like, and can deeply resist inflammation, relieve and maintain stability in an endogenous and endogenous two-way manner, and repair the damaged skin barrier in a multi-level and multi-dimensional manner, so that the skin problems such as skin dryness, roughness, desquamation, redness and swelling, pruritus and the like are improved.

The invention relates to the field of cosmetics, in particular to a sialic acid composition with an acne removing effect, a preparation method of the sialic acid composition and cosmetics. The composition is prepared from 8%-20% of sialic acid, 10%-25% of ectoine, 5%-15% of a humectant, 0.1%-1% of a thickening agent, 0.05%-0.5% of a pH regulator and the balance of water. Cubilose acid can promote collagen synthesis, repair damaged skin barrier and reduce inflammatory response caused by external stimulation, and acne generation is inhibited from acne inducement; meanwhile, the sialic acid can inhibit release of proinflammatory factors such as TNF-alpha and IL-6 by adjusting a TLR receptor signal channel, red and swollen pox is relieved, and the generated pox is inhibited from the aspect of inhibiting inflammation; the sialic acid is non-irritant, and can slightly promote cutin renewal under high concentration, so that the problems of skin desquamation, sensitivity and the like caused by barrier injury can be effectively avoided. Ectoin is compounded, so that the Ectoin and sialic acid can generate a synergistic interaction effect.

The invention relates to a pharmaceutical composition, which is prepared from adapalene, benzoyl peroxide, a traditional Chinese medicine extract, an acrylamide and acryloyl dimethyl sodium taurate copolymer, a mixture of isohexadecane and polysorbate 80, docusate sodium, EDTA (Ethylene Diamine Tetraacetic Acid) disodium, glycerol, poloxamer 124, propylene glycol and water, the traditional Chinese medicine extract comprises moutan bark, salvia miltiorrhiza, radix rehmanniae recen, radix sophorae flavescentis, coptis chinensis, rheum officinale, scutellaria baicalensis, menthol and borneol. According to the pharmaceutical composition disclosed by the invention, the synergistic antibacterial and anti-keratosis curative effects of adapalene and benzoyl peroxide can be maintained, and meanwhile, the occurrence rate of local skin dryness, erythema, desquamation, burning heat sensation and contact dermatitis can be remarkably reduced.

The invention discloses repairing nano-emulsion and a preparation method thereof, and relates to the technical field of cosmetics and skin care products. Comprising the following components in percentage by weight: 1.0 to 5.0 percent of an emulsifier, 1.0 to 5.0 percent of squalane, 2.0 to 10.0 percent of an emollient, 3.0 to 10.0 percent of glycerol, 3.0 to 10.0 percent of butanediol, 0.5 to 3.0 percent of tetrahydromethylpyrimidine carboxylic acid, 0.5 to 3.0 percent of a vetiver root extract, 0.5 to 3.0 percent of a codium tomentosum mixture, 0.5 to 3.0 percent of sodium stearoyl glutamate, 0.1 to 1.0 percent of trihydroxy palmitamide hydroxypropyl myristyl ether, 0.1 to 1.0 percent of xiangyan, 0.1 to 1.0 percent of rape sterols, 0.1 to 1.0 percent of safflower oleosome and the balance of water. The skin care product is prepared from the following components in percentage by weight: 0.1 to 1.0 percent of 5HA hyaluronic acid, 0.05 to 0.5 percent of sickle pod hematoxylon bark extract, 0.05 to 0.5 percent of cornflower extract, 0.1 to 1.0 percent of tocopherol, 0.03 to 0.2 percent of EDTA (Ethylene Diamine Tetraacetic Acid) disodium, 0.03 to 0.1 percent of essence, 0.5 to 2.0 percent of preservative and the balance of deionized water, wherein the total percentage is 100 percent. The nano-emulsion prepared by the invention can help the absorption of active matter components, improve the problems of skin dryness, roughness, desquamation, sensitivity and the like, enhance the water locking capacity of the skin and repair the skin barrier.

This invention discloses a strain of Bifidobacterium animalis subspecies TRT-2A with allergy-relieving effects and its extracellular vesicle applications. The strain TRT-2A is deposited at the China Center for Type Culture Collection (CCTCC) on November 21, 2025, with accession number CCTCC NO:M 20252645. This strain is highly acid-resistant and exhibits good tolerance to artificial gastric and intestinal fluids. It effectively inhibits bacteria, particularly Streptococcus pyogenes, Streptococcus agalactiae, and / or Escherichia coli. Experimental results show that this strain can alleviate hormone-dependent dermatitis and effectively improve dermatitis symptoms such as erythema and desquamation. Furthermore, extracellular vesicles prepared using TRT-2A can effectively improve skin elasticity and reduce wrinkles. Therefore, the Bifidobacterium animalis subspecies TRT-2A of this invention has multiple functions and is worthy of further promotion and application.

This invention provides a novel application of IdeS, which is used to prepare products addressing photoaging of the skin. These products include skincare products and pharmaceuticals for the prevention and / or treatment of photoaging. The pharmaceuticals are in the form of ointments, and the skincare products are used as adjunct treatments for preventing and treating photoaging. IdeS treatment significantly improves the extensive erythema, wrinkles, desquamation, inflammation, and thickened stratum corneum observed in photoaging model mice. It has been developed as a novel biological therapeutic drug with strong pharmacological effects, few side effects, and avoidance of allergic reactions, thus providing a basis for the clinical treatment of photoaging and photodamage.

The utility model discloses a traditional Chinese medicine outer skin stripping device which comprises an operation machine box, a top cover is fixedly connected to the upper portion of the operation machine box, and a first motor penetrates through the upper portion of the top cover. A plurality of groups of peeling racks are fixedly connected to the outer wall of the peeling roller shaft; the vertical feeding opening is formed in the top cover, a vertical partition plate is fixedly connected to the inner wall of the operation machine box, a vertical machining groove penetrating through the front side and the rear side is formed in the partition plate, and the machining groove corresponds to the vertical feeding opening. The utility model belongs to the technical field of traditional Chinese medicinal material processing, and effectively solves the problems that when a traditional Chinese medicinal material skin stripping device is used, skin stripping is not thorough, the trouble of follow-up production and processing is increased, and feeding and discharging are inconvenient.

The invention relates to the technical field of light control, in particular to a skin visual detection control method based on a silicon substrate multi-primary-color LED lamp. According to the method, the original skin image is continuously acquired, the local window is divided, and the similarity of the structure direction field and the color gradient field of the local texture is combined, so that the high-resolution recognition of the skin texture state is realized, and the recognition precision of the facial detail abnormity is enhanced. By setting the fuzzy judgment interval and quantifying the membership degree, a multi-dimensional recognition system for different abnormal types such as color spots, redness and swelling, dry decrustation, acnes and comedos is established, and the sensitivity and adaptability of skin abnormality judgment are remarkably improved. In a color response interference identification process, an inter-class variance is introduced to calculate a response difference between a red channel and a yellow channel, so that the influence of a color overlapping region is effectively eliminated, and the effectiveness and independence of extracting a gray region are ensured. And further extracting an effective gray area in the non-interference area.

The invention discloses a hair-growth Chinese medicine composition, comprising 500g-800g of astragalus, 300g-400g of cinnamon bark, 300g-500g of oriental arborvitae leaf, 300g-400g of processed polygonum multiflorum, 300g-450g of psoralea corylifolia, 200g-400g of drynaria, 150g-350g of angelica, 100g-250g of safflower, 120g-260g of asarum and the like. The hair-growth Chinese medicinal composition of the present invention comprises ingredients such as Polygonum multiflorum, Platycladus orientalis leaves, Psoralea corylifolia, Rhizoma Drynariae and the like. The various Chinese medicinal ingredients can cooperate with each other to invigorate qi, activate blood circulation and dredge meridians; can regulate the growth environment of hair, promote blood circulation in the head, repair damaged hair follicles and promote the growth of new hair; can achieve a good therapeutic effect on seborrheic alopecia; can reduce the irritation of hair-growth fluid to the scalp, and reduce the occurrence of skin pathological symptoms such as rashes, pustules, peeling, urticaria, itching and pain.

The present invention relates to human tissue kallikrein 7 (KLK7) selective inhibitor compounds, combinations including these compounds, process to obtain the referred compounds, and methods of using the same. The present invention belongs to the field of chemistry, pharmacology and medicine.

The invention relates to the field of skin sampling tools, and discloses an eczema patient skin lesion sampler which comprises a sampler body, a detection mechanism and a cutting mechanism are arranged in the sampler body, the detection mechanism is used for detecting the position and state of the skin lesion of a patient, and the cutting mechanism is used for cutting the skin lesion of the patient. The cutting mechanism is used for sampling a skin lesion area of a patient, the sampler body comprises a protective shell, a handle shell is arranged at the bottom of the protective shell, the protective shell is connected with the handle shell, the cutting mechanism comprises a cutting bin, and a plurality of baffles are arranged in the cutting bin. According to the invention, the detection mechanism is used for accurately identifying the state of a skin lesion part, and differential cooperation of multiple groups of cutting knives in the cutting mechanism is combined, so that corresponding sampling is realized for different states such as acute exudation, subacute and chronic desquamation and crust, and the problems of slow sampling and influence on a test result caused by eczema state difference in the prior art are solved; and the sampling efficiency and accuracy are improved.

The present application relates to the technical field of food peeling, and particularly relates to a skin removing device and method for production of dendrobium officinale, which comprises a base, a peeling assembly is installed in the base, the peeling assembly comprises a peeling shell body arranged above the base, a skin screening barrel is fixedly connected in the peeling shell body, a feeding pipe is communicated to one side of the skin screening barrel, a material taking opening is arranged on the side wall of the peeling shell body, the peeling shell body is controlled to rotate through a driving motor, a heating pipe is communicated in the peeling shell body, a connecting opening is communicated to the side wall of the heating pipe, and the connecting opening is used for being connected with an external heating air pump; a swing assembly is arranged on one side of the heating pipe, the swing assembly comprises a rectangular cylinder fixedly connected to one side of the heating pipe, a swing block is arranged on the side wall of the rectangular cylinder, an air outlet is arranged in the swing block, and the air outlet is communicated with the connecting opening. The present application solves the problems of the prior art that the raw materials are easily damaged and the separation effect is poor, and the present application cannot be adapted to industrialized continuous production.

The invention relates to the field of biological medicine, in particular to recombinant jellyfish thioredoxin cream as well as a preparation method and application thereof. The emulsifiable paste is prepared by mixing recombinant jellyfish thioredoxin with efficient transmembrane capacity and remarkable antioxidant activity as a main component with an emulsifiable paste matrix. The adverse symptoms such as skin dryness, desquamation and wrinkles damaged by ultraviolet radiation can be obviously relieved, and the epidermal hyperplasia and skin oxidative stress level can be improved. The jellyfish-derived antioxidant is externally applied to skin ultraviolet radiation injury protection for the first time, a new medicine source is provided for preventing skin ultraviolet radiation injury, and a new application field is expanded for jellyfish biological resource development.

The invention belongs to the technical field of cosmetics, and discloses a skin-soothing barrier composition capable of being used for children suffering from eczema and application of the skin-soothing barrier composition. The skin-soothing barrier composition is prepared from the following components in parts by mass: 0.05 to 4 parts of fructus schisandrae chinensis extract, 0.1 to 3 parts of tetrahydromethylpyrimidine carboxylic acid, 0.05 to 3 parts of lactobacillus / algae extract fermentation product, 0.05 to 3 parts of glycosylglycerol and 0.3 to 5 parts of capparis spinosa fruit extract. Through the combination of the specific components, a good synergistic effect is generated among the components, the effects of resisting inflammation, relieving, moisturizing, locking water, resisting oxidation and the like are effectively improved, on one hand, oxidative stress injury is relieved, and red-sensitive scorching heat is relieved; on the other hand, dry desquamation is improved by repairing keratinocytes and reinforcing a barrier; therefore, a more comprehensive improvement effect is achieved on symptoms such as repeated attack of eczema, itching and discomfort, dryness and desquamation, red sensitivity and scorching heat of children and the like.

The present invention provides a method and a pharmaceutical composition for treatment of skin diseases associated with accelerated comeodesmosomes degradation and / or weaker cell-cell adhesion, such as a peeling skin syndrome, Netherton syndrome, and atopic dermatitis.

The application discloses a use of a topical preparation containing crocetin or a pharmaceutically acceptable salt thereof. The topical preparation developed in the application is used for treating cheilitis simplex actinica caused by chemotherapy, is convenient to use, has few toxic and side effects, and can effectively relieve symptoms such as cheilitis simplex actinica, lip crack, desquamation, erosion and scabbing caused by chemotherapy. The application also expands the application field of crocetin drugs, and finds a new use of crocetin and the salt thereof, which can be prepared into a topical preparation for preventing / treating skin inflammation or skin damage, especially for preventing / treating cheilitis simplex actinica caused by chemotherapy and skin damage caused by oxidative stress, and has better effects. When the crocetin and the salt thereof are used in combination with chlorogenic acid, they have better therapeutic effects. The crocetin and the salt thereof have higher stability when prepared into the topical preparation, are easier to obtain high-purity products, and are more suitable for pharmaceutical development.

There is a need to have novel active agents that act against excessive desquamation of the skin or the scalp, in order to limit and / or prevent desquamation and thereby contribute to skin comfort.SOLUTION: The present invention relates to an alcoholic extract of the peel of Citrus aurantium, to a cosmetic composition comprising such an extract, in particular having a preventive effect on skin desquamation, and to a process for the preparation thereof.SELECTED DRAWING: Figure 1

The invention relates to the technical field of control, in particular to a ginger processing production line control method. Analyzing by combining historical ginger peeling records and preset skin removal indexes to obtain a plurality of expected residual skin proportions of the plurality of peeling stages; initial peeling parameters are set based on the ginger attribute characteristics of the to-be-peeled ginger, and peeling equipment is controlled to execute peeling operation in a first peeling stage according to the initial peeling parameters; performing peeling state identification on the first peeled ginger image to obtain a first predicted residual peel proportion; performing peeling parameter optimization according to the ginger attribute characteristics and the first predicted residual peel proportion, and outputting a second optimal peeling parameter; and according to a second optimal peeling parameter, performing peeling operation of a second peeling stage, performing iterative feedback control, and stopping the fresh ginger peeling operation until the fresh ginger peeling period is completed or the current predicted residual skin proportion is smaller than or equal to a preset skin removal index. The ginger peeling precision, efficiency and product quality stability are obviously improved.

The invention belongs to the field of daily necessities, and particularly relates to a soothing nutritional cream suitable for the skin of a diabetic patient, which takes ceramide NP, 4-tert-butyl cyclohexanol, a cynanchum atratum extract, bisabolol and a robinia pseudoacacia flower extract as main active ingredients of a repair cream, and is matched with a humectant, an emulsifier, an emollient, an antioxidant, an oil phase and a water phase matrix. The obvious effects of relieving the phenomena of decrustation, chap and the like caused by dry skin of hands and feet of the diabetic patient, strengthening the natural barrier function of the skin and relieving the symptom of skin itch are synergistically realized.

The invention belongs to the field of daily necessities, and particularly relates to a hand and foot repair cream suitable for diabetics, which is prepared by taking ceramide NP, 4-tert-butyl cyclohexanol, blackend swallowwort root extract, bisabolol and robinia pseudoacacia flower extract as main active components of the repair cream, and matching with a humectant, an emulsifier, an emollient, an antioxidant, an oil phase and a water phase matrix. The obvious effects of relieving the phenomena of decrustation, chap and the like caused by dry skin of hands and feet of the diabetic patient, strengthening the natural barrier function of the skin and relieving the symptom of skin itch are synergistically realized.

The utility model provides a blood disease chemotherapy patient skin care device which comprises a care device bottom plate, a connecting plate is fixedly arranged on one side of the top end of the care device bottom plate, a control handle is installed at the top end of the connecting plate, the control handle is in an L shape and can be conveniently held by medical staff, and a heat dissipation plate is fixedly arranged at one end of the care device bottom plate. According to the scheme, the medicine spraying plate is controlled to be started by pressing the control button, at the moment, the medicine spraying plate is started, the atomization spray head is turned on and turned off, and nursing liquid medicine in the storage disinfection tank is atomized outwards through the atomization spray head and applied to the positions, where symptoms occur, such as swelling, itching, dryness, desquamation and even ulceration, of the skin surface of a patient; and the skin care work of medical personnel is facilitated.

A transdermal drug administration system comprising: a first ultrasonic wave production means that emits first ultrasonic waves with a low frequency into skin, in order to cause peeling due to cavitation in the stratum corneum of the skin; and a second ultrasonic wave production means that produces an acoustic flow by emitting second ultrasonic waves with a higher frequency than that of the first ultrasonic waves, in order to cause a drug to penetrate under the corneum in which the peeling has occurred.

The invention relates to the technical field of cosmetics, in particular to application of mogroside V in preparation of skin barrier repair cosmetics, the mogroside V serves as an active ingredient, the purity of the mogroside V is not lower than 30%, and the mogroside V can be prepared into various cosmetic dosage forms such as toning lotion, facial masks and essence cream. The mogroside V has no significant toxicity to keratinocytes, can accelerate skin barrier repair by promoting cell migration, has significant antioxidant activity, and can scavenge free radicals, reduce oxidative stress injury and realize synergistic effects of barrier repair and oxidation resistance and aging resistance. Besides, mogroside V is a natural water-soluble component, can be stably dispersed in a water-based formula without a solubilizer, is free of thick and sticky feeling during use, and solves the problem of skin feeling pain points of traditional repairing components. The barrier damage problems of dry skin, redness, desquamation and the like can be improved in a targeted manner, and the application prospect is wide.

The present invention provides a method of preventing or treating inflammatory skin diseases by administering a composition comprising at least one milk-derived protein. The invention also relates to a method for moisturizing dry skin, softening skin, reducing skin itch, reducing skin desquamation, reducing skin redness, reducing rough skin, reducing skin swelling, reducing skin dehiscence, renewing skin cells, protecting hand skin or any combination thereof.

The invention relates to the related technical field of sub-health conditioning cabins, in particular to a sub-health conditioning cabin with infrared induction safety protection, which comprises a sub-health conditioning cabin, a built-in infrared temperature sensor monitoring cabin, a platform and an infrared induction assembly. The built-in atomization nozzles are distributed and mounted on the two sides of the built-in infrared temperature sensor monitoring cabin through the mounting plates, a medicament and a water source are injected into the sub-health conditioning cabin and the built-in infrared temperature sensor monitoring cabin through the connecting ends and the water pipes, and then spraying is performed through the built-in atomization nozzles; the water replenishing device has a water replenishing effect on the skin of a user, the situation that when the user is exposed to infrared irradiation for a long time, skin moisture evaporation is accelerated is avoided, water can be replenished to the skin in time, burning is prevented, skin dryness, rough decrustation and the like are prevented, and medicament atomization treatment and conditioning are further facilitated.

The application discloses a peanut wet red skin removing machine and belongs to the technical field of agricultural processing machinery. The peanut wet red skin removing machine comprises a rack, a red skin removing device, a pressing device, a skin cutting device, an extruding device, a skin cleaning device, a flying preventing device, a feeding port, a discharging port, a transmission device and a power device which are arranged on the rack. The red skin removing device comprises a plurality of red skin removing wheels which are arranged side by side and side plates which are arranged on the two sides of the red skin removing wheels. A feeding port and a discharging port are respectively arranged on one side plate. A feeding channel and a discharging channel which are communicated with the feeding port and the discharging port respectively extend into the red skin removing wheels. The pressing device, the flying preventing device and the skin cutting device are arranged in the inside of the red skin removing wheels in sequence in the clockwise direction. The skin cutting device is arranged at the uppermost position. The extruding device is arranged on the outside of the red skin removing wheels and is located below the skin cutting device. The skin cleaning device is arranged below the extruding device. The inside gap of the red skin removing wheel is larger than the outside gap. The peanut wet red skin removing machine can improve the red skin removing and cleaning rate of peanuts, reduce the breakage rate, remove the red skin of different varieties of peanuts and improve the universality of the red skin removing machine.

The present invention discloses a highly stable whitening and anti-aging atomizing solution. The preparation raw materials include enzyme activity inhibitors, polysaccharide substances, calcium sodium phosphosilicate, skin conditioners, polypeptides, vitamins, edible flavors, and polar solvents. The obtained atomizing solution can improve the cell discrimination ability and regulate the half-life of blood proteins, thereby effectively enhancing the human immune function; activate the fibroblasts generated by the human dermis, significantly promote the synthesis of collagen in the human body, effectively improve the stratum corneum, promote the skin to be soft and elastic, and make the skin young and plump; can establish a network structure on the skin surface to achieve long-term water locking, effectively relieve skin dryness and desquamation, and form a natural defense barrier for the skin; has super antioxidant ability, and enhances the skin's anti-photoaging and anti-ultraviolet radiation performance. Moreover, it has good thermal stability, and the active ingredients will not decompose under the high temperature condition of 220°C. At the same time, it can promote the rapid atomization of the atomizing solution, and the formed mist has a high saturation.

The invention provides a compound lotion suitable for dissolving traditional Chinese medicines as well as a preparation method and application thereof, and relates to the technical field of daily chemical products. The compound washing agent is composed of a specific content of a surfactant system, a nonionic solubilizer and a cationic conditioner. Wherein the mass ratio of the cocamidopropyl betaine to the sodium laureth sulfate to the sodium lauroyl sarcosine is (2.0 to 2.5) to (8.0 to 9.0) to (2.8 to 3.2). According to the compound lotion obtained by synergistically compounding the surfactant system, the nonionic solubilizer and the cationic conditioner, on one hand, the compound lotion can be independently applied to effectively relieve discomfort such as scalp greasiness, itching and desquamation; on the other hand, the compound lotion has better compatibility and solubility for the traditional Chinese medicine particles, and on the premise of high drug loading capacity of the traditional Chinese medicine particles, the shampoo is stable in character and good in washing feeling, and the preparation requirements of the traditional Chinese medicine particle shampoo can be fully met.