342 results about "Seborrheic dermatitis" patented technology

Hyperactive glandular conditions are treated using topically formulated botulinum toxin compositions. In the preferred embodiment of the invention, topical botulinum preparations are applied directly to the skin by a patient as needed to suppress his or her hyperhidrosis, bromhidrosis, chromhidrosis, nevus sudoriferous, acne, seborrhiec dermatitis or other glandular condition. In other embodiments, topical botulinum toxins are applied with the aid of mechanical, electrical, and / or chemical transdermal delivery enhancers.

This application relates to a stable pharmaceutical composition and methods for the cleansing of skin to facilitate the prevention, treatment, and management of skin conditions, such as seborrheic dermatitis, psoriasis, folliculitis, rosacea, perioral dermatitis, acne, impetigo and other inflammatory skin conditions, and the like, including a sufficient amount of an acidic component of a hydroxyacid or tannic acid, or a pharmaceutically acceptable salt thereof, to exfoliate a portion of the skin, a sufficient amount of stabilized hydrogen peroxide to facilitate cleansing of the skin without substantial irritation thereof, and an antimicrobial agent including at least one of an antibacterial agent, antimicrobial agent, antiviral agent, anthelmintic, or a combination thereof, in an amount sufficient to inhibit or reduce microorganisms on the skin.

This application relates to a stable pharmaceutical composition and methods for the cleaning of skin to facilitate the prevention, treatment, and management of skin conditions, such as seborrheic dermatitis, psoriasis, folliculitis, rosacea, perioral dermatitis, acne, impetigo and other inflammatory skin conditions, and the like, including a sufficient amount of an acidic component of a hydroxyacid or tannic acid, or a pharmaceutically acceptable salt thereof, to exfoliate a portion of the skin, a sufficient amount of stabilized hydrogen peroxide to facilitate cleansing of the skin without substantial irritation thereof, and an antimicrobial agent including at least one of an antibacterial agent, antimicrobial agent, antiviral agent, anthelmintic, or a combination thereof, in an amount sufficient to inhibit or reduce microorganisms on the skin.

Dermatological conditions / afflictions such as rosacea, common acne, seborrheic dermatitis, perioral dermatitis, acneform rashes, transient acantholytic dermatosis, and acne necrotica miliaris, most notably rosacea, are treated by topically applying onto the affected skin area of an individual in need of such treatment, a topical pharmaceutical composition which comprises a thus effective amount of ivermectin.

The invention provides a cosmetic composition and uses thereof. The cosmetic composition comprises an active ingredient and a matrix, wherein the active ingredient is calcium dobesilate. The cosmetics can be made into solution, soap, cream, tincture, film, gel, shampoo and toothpaste type. The calcium dobesilate in the cosmetic composition has the effects of improving skin capillary circulation and reducing skin telangiectasia. The cosmetic composition can be used for preparing cosmetics for caring skin, preventing alopecia, promoting hair growth, protecting gums and strengthening teeth, removing facial blood streak and ecchymoses, and preventing and treating seborrheic dermatitis, rosacea and acne.

The invention relates to an oral traditional Chinese medicine for treating skin diseases. The oral traditional Chinese medicine is prepared from radix lithospermi, rhizoma smilacis glabrae, fructus gardeniae, cortex dictamni, common peony roots, radix scrophulariae, rehmanniae radix, isatis indigotica forts, radix sophorae flavescentis, lalang grass rhizome, flos sophorae, radix sileris, puncturevine caltrop fruits, red-rooted salvia roots, ligusticum wallichii, large-leaved gentian, processed polygonum multiflorum, Chinese angelica, white paeony roots and licorice roots. The oral traditional Chinese medicine is a pure traditional Chinese medicine prescription, reduces the recurrence rate of psoriasis and obviously improves the cure rate. In the invention, by mixing the Chinese angelica, the white paeony roots, the isatis indigotica forts and the licorice roots for use, the organism immunity can be enhanced greatly and the problem of recurrence of the psoriasis due to cold and pharyngitis can be solved. The oral traditional Chinese medicine has high effective rate to the psoriasis more than 98 percent and also has 100 percent cure rate to conventional skin diseases such as acne, cutaneous pruritus, pityriasis rosea, eczema, lichen planus, neurodermatitis, urticaria, seborrheic dermatitis, and the like.

The invention provides shampoo containing chlorine dioxide, which is prepared from surfactant, chelant, humectant, conditioner, thickening agent, chlorine dioxide or chlorine dioxide precursor, pH regulator and deionized water at a certain weight ratio. The invention successfully introduces internationally accepted safest, most effective and environmentally-friendly A1-grade green disinfectant-chlorine dioxide into a shampoo system. The shampoo has moderate quality, is safe and protects environment; after being washed, hair is wet, soft and glossy. The shampoo overcomes the defects of the existing anti-dandruff shampoo and truly realizes that the processes of washing hair, caring hair and removing dandruff can be achieved in one step, people feel that scalp is relaxed after washing hair, and dandruff does not relapse. The shampoo is suitable for people who suffer from dandruff and has favorable curative effect on dandruff and tinea capitis due to seborrheic dermatitis, so that people can trustingly use the shampoo for a long term.

The present invention provides unique, efficacious, inexpensive, safe, reliable, convenient, minimally bitter, skin protecting and penetrating, easy-to-administer base compositions and active agent-containing compositions, such as those including hydrocortisone, and related production and topical application methods, for treating the skin of mammals for a wide variety of different dermatologic conditions, disorders and diseases, such as inflammation, redness, cracking, insect bites, dryness, allergic reactions, trauma, irritant dermatitis, perleche, contact dermatitis, psoriasis, eczema, seborrheic dermatitis, acne excoriate, xerosis, eczema craquele, stasis dermatitis, disease related conditions and dryness from medications such as isotretinoin, acitretin and lipid lowering agents. This is effected by topically administering, or otherwise applying, effective amounts of the compositions thereto in forms that not only address the skin and mucosa of the mouth and lips, but also of the rest of the body and, in particular, areas where other topical balms containing hydrocortisone and other active ingredients have not been developed or marketed. Additionally, the flavoring addition to this product, and the base wherein the active ingredient(s) reside, affords a significantly better tasting, and less bitter, composition, thereby allowing a more pleasant experience and better compliance by patients. Larger sized stick formulation(s) allow for more applicability of the product, and more usefulness thereof, in various areas, and mucosal skin, of the body. The compositions include a unique formulation of FANCOL VB, Natunola Castor 1023, Finsolv TN, bees wax and, optionally, one or a plurality of plant or plant seed oils, fatty alcohols, fats and flavorings, in desirable weight percents thereof, in various forms, and preferably in the form of a solid roll-on stick present in a variety of sizes.

Dermatological conditions / afflictions such as rosacea, common acne, seborrheic dermatitis, perioral dermatitis, acneform rashes, transient acantholytic dermatosis, and acne necrotica miliaris, most notably rosacea, are treated by topically applying onto the affected skin area of an individual in need of such treatment, a topical pharmaceutical composition which comprises a thus effective amount of ivermectin.

Hyperactive glandular conditions are treated using topically formulated botulinum toxin compositions. In the preferred embodiment of the invention, topical botulinum preparations are applied directly to the skin by a patient as needed to suppress his or her hyperhidrosis, bromhidrosis, chromhidrosis, nevus sudoriferous, acne, seborrhiec dermatitis or other glandular condition. In other embodiments, topical botulinum toxins are applied with the aid of mechanical, electrical, and / or chemical transdermal delivery enhancers.

The invention relates to a traditional Chinese medicine for treating scalp seborrheic dermatitis. The traditional Chinese medicine comprises, by weight ratio, the following raw medical materials of 12 parts of screen grass, 9 parts of eggplant roots, 15 parts of millennium mugwort, 9 parts of cladonia alpestris, 6 parts of pellionia repens, 6 parts of flos sophorae and 12 parts of radix rehmanniae. The clinical trials prove that the traditional Chinese medicine can treat scalp seborrheic dermatitis safely and effectively.

A composition for topical treatment of dermatitis is provided. The composition includes one or more anti-histamines or a pharmaceutically acceptable salt thereof; one or more polysaccharides; and one or more Group 1, 2, or 13 metal hydroxides. The dermatitis may be a poison ivy, poison oak, poison sumac, diaper rash, eczema, lichen simplex chronicus, rashes, dermatoses, seborrheic dermatitis, psoriasis, atopic dermatitis, or the combination thereof A method of treatment of dermatitis is also provided.

The present invention relates to compositions comprising a proanthocyanidin, as well as methods for using such compositions in the treatment of an inflammatory condition of the skin including, but not limited to, atopic dermatitis(eczema), allergic contact dermatitis, seborrheic dermatitis, psoriasis, xerosis and atopia, as well as treatment of an inflammatory condition of mucosae and of an inflammatory condition in the eye. The present invention also relates to compositions comprising a proanthocyanidin, glycyrrhetinic acid and telmesteine, as well as methods for using such compositions in the treatment of an inflammatory condition of the skin including, but not limited to, atopic dermatitis, allergic contact dermatitis, seborrheic dermatitis, radiation dermatitis, psoriasis, xerosis and atopia, as well as treatment of an inflammatory condition of mucosae and of an inflammatory condition in the eye.

A cleanser composition composed of purified water, sodium laureth sulfate, zinc pyrithione, cocamidopropyl betaine, glycerol cocoate, polyquaternium-7, and a cross-linked polyacrylic acid polymer for topical application to an area affected by a skin disorder such as seborrheic dermatitis, perioral dermatitis, rosacea, acne, tinea versicolor, eczema and psoriasis.

A method for treating dermatological conditions as eczema, seborrheic dermatitis, psoriasis and allergic skin reactions such as hives, skin irritations, poison ivy, poison oak, and the like. The method involves applying to the affected area of the skin a few drops of a combination of pheniramine maleate and either naphazoline HCL or phenylephrine HCL and then applying to the same affected area a topical corticosteroid cream, ointment or lotion. The preferred ratio is approximately one drop of solution for every approximately 0.1 grams of topical corticosteroid cream applied to each patch of skin affected with any of the dermatological conditions.

The invention relates to compound emulsifiable paste for treating acne and a preparation method thereof, in particular to a medicament for treating acne and a preparation method thereof. The compound emulsifiable paste solves the problems of long treatment course and skin oxidation, dim skin and formation of color spots in the healing process in the conventional medicament for treating the acne. The compound emulsifiable paste is prepared from clindamycin hydrochloride, metronidazole, vitamin A, vitamin C, an emulsifying agent, stearic acid, albolene, glycerol monostearate, lanolinum, glycerol and purifying water. The preparation method comprises the following steps of: adding the vitamin A into uniform solution prepared from the stearic acid, the albolene, the glycerol monostearate and the lanolinum to obtain an oil phase; dissolving the glycerol and the emulsifying agent into the purifying water, adding the clindamycin hydrochloride, the metronidazole and the vitamin C, and stirring uniformly to obtain a aqueous phase; and adding the oil phase into the aqueous phase, stirring, homogenizing and standing the mixture to obtain the compound emulsifiable paste for treating the acne. The treatment period of the compound emulsifiable paste is between 14 and 24 days, skin is bright and clean after healing, and the compound emulsifiable paste can treat the acne, seborrheic dermatitis, acne rosacea and folliculitis.

The invention discloses a fermentation traditional Chinese medicine combination for liquid shampoo and a preparation method of the combination. The fermentation traditional Chinese medicine combination is prepared after traditional Chinese medicines of lightyellow sophora root, safflower flower, common cnidium fruit and pricklyash peel are fermented by bacillus subtilis and yeaster, combined with amur corktree bark, rhizome of Chinese goldthread and baical skullcap root extracts and added into a chitosan-acetic acid solution. The fermentation traditional Chinese medicine combination can be used for preparing anti-scurf shampoo products. Experiments show that the shampoo products comprising the fermentation traditional Chinese medicine combination have remarkable inhibiting effects on malassezia fufur and remarkable efficacy for curing seborrheic dermatitis.

The invention provides a traditional Chinese medicine external preparation for curing dermatitis and eczema, which is prepared from the following raw materials in part by weight: 10-30 parts of gall bladder, 10-20 parts of fructus cnidii, 10-20 parts of lithospermum, 10-20 parts of groundsel, 10-20 parts of radix sophorae flavescentis, 10-20 parts of soapberry, 10-20 parts of angelica sinensis, 10-20 parts of caulis spatholobi, 10-20 parts of radix angelicae, 10-20 parts of rhizoma bletillae, 10-20 parts of rhizoma bletillae, 10-20 parts of golden cypress, 10-20 parts of mentha haplocalyx and 10-20 parts of cortex dictamni. The external preparation has the efficacies of clearing away heat and toxic materials, relieving itching and pain, diminishing inflammation and sterilizing, detumescence and the like, can be widely applied to curing eczema, seborrheic dermatitis, tinea and other intractable skin diseases, adopts drug components for clearing away heat and drying dampness, dispelling the wind and killing insects, and promoting pus discharge and tissue regeneration, permeates through the body through skin and enhances the curing effect, thereby improving the curative effect. The drug provided by the invention, is quick in itch dispelling, quickens the self-healing speed of skin, removes toxins in skin, improves the self immunity and generates no side effect on human bodies.

Methods of treating inflammatory skin diseases such as rosacea, atopic dermatitis, contact dermatitis, drug eruptions, psoriasis, seborrheic dermatitis, connective tissue diseases, autoimmune disorders, urticaria or hives, and inflammation associated with skin infections by topical or systemic administration of a nitroxide containing compound are provided.

The invention belongs to the field of traditional Chinese medicine compositions, and particularly relates to a traditional Chinese medicine composition for treating a skin disease and a preparation method thereof. The traditional Chinese medicine composition is prepared from, by weight, 3-5 parts of cortex pseudolaricis, 1.5-3.5 parts of radix et rhizoma rhei, 7-10 parts of cortex moutan, 8-15 parts of fructus kochiae, 7-10 parts of oriental variegated coralbean bark, 7-10 parts of coptidis rhizoma, 8-15 parts of cortex dictamni, 7-10 parts of cortex phellodendri, 7-10 parts of cortex meliae, 7-10 parts of radix scutellariae, 8-15 parts of fructus cnidii, 8-15 parts of radix sophorae flavescentis, 4-6 parts of salicylic acid, 8-12 parts of benzoic acid, 0.6-0.9 part of phenol, 4-6 parts of borneol, 4-6 parts of menthol crystals, 4-6 parts of dried alum and 4-6 parts of glycerin. According to the traditional Chinese medicine composition for treating the skin disease, the course of treatment is short, the effect is quick, the cause of a disease can be eliminated, relapse is not prone to occurrence, no toxic or side effect exists, and psoriasis, various fungal infections, eczema, seborrheic dermatitis, rhagadia of hands and feet, palmoplantar pustulosis, pityriasis rosea and neurodermatitis can be radically treated.

The invention provides gene sequences of wild type, S252W mutant type and P253R mutant type FGFR2b ectodomains and polypeptides coded thereby respectively. A preparation system of the polypeptide comprises a recombinant vector, a host cell and a preparation method, an antibody of FGFR2b ectodomain and a preparation method thereof as well as a fusion polypeptide, an antagonist and the like of the FGFR2B ectodomain and Fc domain. The invention also provides an application of the polypeptide of FGFR2b ectodomain and a composition in treating eczema, acne, psoriasis, skin allergy, seborrheic dermatitis or alopecia seborrheica; an FGF signal channel is inhibited through the FGFR2b ectodomain, the symptoms such as swelling, pruritus and the like of inflammatory skin diseases are inhibited, and an inhibitory effect is also realized on the sebum secretion.

The invention relates to a Chinese medicinal composition for treating skin diseases. The Chinese medicinal composition is prepared by stir-frying various Chinese herbal medicines such as phellodendron, baical skullcap root, manchurian wildginger, schizonepeta spike, bulbus fritilariae, golden larch bark, sulphur, realgar, toad venom, musk, mint rice, plant soot, salicylic acid and the like over slow fire, grinding accurately, mixing with badger fat, antelope oil and the like, grinding again and extracting. The Chinese medicinal composition can remove abnormal phlegmatic temperament, bile fluid and sepsis and relieve swelling and itching, and is used for treating parapsoriasis guttata (psoriasis), tinea manuum, tinea corporis, tinea pedis, tinea versicolor, intractable dermatitis, neurodermatitis, fungal skin diseases, leuconychia, purulent skin diseases, facial pityriasis, pityriasis rosea, seborrheic dermatitis, prurigo nodularis, scabies, eczema, herpes, acnes and the like.

The nanometer antifungal econazole nitrate emulsion medicine consists of econazole nitrate, surfactant, oil and distilled water. Its preparation process includes the following steps: weighing the materials; mixing the surfactant and oil and dissolving econazole nitrate in dimethyl sulphoxide; mixing the solution of econazole nitrate with the surfactant and oil; and final adding distilled water slowly while stirring to form stable homogeneous transparent nanometer antifungal econazole nitrate emulsion medicine. The medicine is used in treating candidal tinea corporis, tinea cruris and tinea pedis, aural mycosis, seborrheic dermatitis, etc. The medicine is absorbed through skin to enter into blood circulation, and this avoids the first pass effect of liver, prolongs the medicine release and prevents stimulation to gastrointestinal tract. The preparation process is simple and low in power consumption.

The invention relates to an external use ointment used for treating dermatitis and a preparation method thereof. An effective compound of the external use ointment comprises following raw materials: caragana microphylla, sundew, alternanthera sessilis, convolvulus arvensis, excoecaria sebifera, acronychia leaf, wing nut leaf, kazinoki broussonetia, calamint, gingium verum, vitex trifolia, ferb of desertliving asparagus, chenopodium album seed, mosla scabra, fruit of siberian nitraria and lantana camara. The external use ointment has efficacies of clearing heat and removing toxicity, eliminating dampness and relieving itching, and coursing wind and nourishing blood; and has significant effects on treatment of allergic dermatitis, atopic dermatitis, neurodermatitis, seborrheic dermatitis and dermatitis medicamentosa; possesses excellent curative effects on common dermatitis diseases such as erythema, papule, rahagades, desquamation, small abscess, pruritus, tenderness and burning heat sensation; and is capable of killing bacteria on human skin surface rapidly and efficiently, removing corrupted materials, promoting optimization and growth of epidermis cells effectively, enhancing plastid of epidermis cells, and helping damaged human body to recover rapidly.

The invention belongs to the field of traditional Chinese medicines, and in particular relates to traditional Chinese medicine healthcare hair shampoo which is prepared from the following raw materials: coconut oil fatty acid diethanolamide, ethylenediaminetetraacetic acid disodium, ammonium lauryl sulfate, alkyl polysaccharide glycoside, cocamidopropyl betaine, N,N-dimethyldodecylamine oxide, cationic guar gum, dimethiconol, D-panthenol, pyrithione zinc, polyquaternary ammonium salt, glycerol, citric acid, matrine extracts, gentian extracts, ginger extracts, isothiazolinone, sodium chloride and deionized water. The traditional Chinese medicine healthcare hair shampoo provided by the invention has the effects of killing bacteria and relieving itching, removing schuppen and treating tinea capitis, and the like, is applicable to people in different ages, has a remarkable treatment and inhibition effect on seborrheic dermatitis and can promote growth of hair, prevent hair from slitting or damage, improve the density of hair and enable hair to be glossy and bright.

The present invention relates to compositions comprising a proanthocyanidin, as well as methods for using such compositions in the treatment of an inflammatory condition of the skin including, but not limited to, atopic dermatitis(eczema), allergic contact dermatitis, seborrheic dermatitis, psoriasis, xerosis and atopia, as well as treatment of an inflammatory condition of mucosae and of an inflammatory condition in the eye. The present invention also relates to compositions comprising a proanthocyanidin, glycyrrhetinic acid and telmesteine, as well as methods for using such compositions in the treatment of an inflammatory condition of the skin including, but not limited to, atopic dermatitis, allergic contact dermatitis, seborrheic dermatitis, radiation dermatitis, psoriasis, xerosis and atopia, as well as treatment of an inflammatory condition of mucosae and of an inflammatory condition in the eye.

A Chinese medicine for treating dermatopathy, such as acne, seborrheic dermatitis, eczema, foll iculitis, etc is prepared from 8 Chinese-medicinal materials including honeysuckle flower, forsythia fruit, forsythia fruit, chrysanthemum flower, scutellaria root, etc.

Methods and systems for determining functional relationships between a skin-active agent and a skin condition of interest, and methods and systems for identifying cosmetic agents effective for treatment of dandruff, as well as the use of agents identified by such methods and systems for the preparation of cosmetic compositions, personal care products, or both are provided. Methods for developing in vitro models of skin disease and models for specific skin diseases are also provided.