170 results about "Thymol" patented technology

The invention relates to the technical field of coatings, in particular to a corrosion-resistant coating material and a preparation method thereof. The corrosion-resistant coating material comprises the following components in parts by mass: 80-100 parts of epoxy resin, 5-20 parts of a modified phenolic aldehyde amine curing agent, 2-5 parts of a waterproof agent, 5-10 parts of a corrosion inhibitor and 40-55 parts of a lubricant. The modified phenolic aldehyde amine curing agent is obtained by carrying out Mannich reaction on phenol, thymol, aliphatic polyamine and formaldehyde. The phenol provides a rigid benzene ring structure, and endows a cured product with good heat resistance and chemical resistance. Thymol improves the flexibility and adhesive force of the cured product and enhances the hydrophobicity of the cured product at the same time. The epoxy resin and the modified phenolic aldehyde amine curing agent are polymerized, the waterproof agent, the corrosion inhibitor and the lubricant are wrapped, and the obtained coating material has good adhesive force and corrosion resistance.

The invention provides a tropical fruit preservative film which is of a double-layer structure, the outer layer is a moisture-resistant antibacterial layer, and the inner layer is a water-absorbing antifogging antibacterial layer; and the water-absorbing anti-fog antibacterial layer also comprises a pH sensitive microcapsule. The outer layer is prepared from polyhydroxyalkanoate, a humidity sensitive type block copolymer and CuO / SiO2 antibacterial nano-enzyme; and the water-absorbing anti-fog antibacterial layer comprises polyhydroxyalkanoate, a humidity-sensitive block copolymer, hygroscopic zeolite, thymol, gallic acid and a pH-sensitive microcapsule. The preservative film has a certain hydrophobic effect, the humidity of a packaging microenvironment can be adjusted, breeding of putrefying bacteria can be inhibited, meanwhile, thymol and gallic acid form a slow-release antibacterial system, and tropical fruits keep good quality in the storage and transportation links through cooperation of all the components; besides, the pH sensitive microcapsules can respond to acidic substances generated by corruption in real time, help merchants to quickly sort deteriorated fruits, and provide a visual judgment basis for consumers at the same time.

The invention discloses an intelligent modified atmosphere packaging film with gas selectivity and pH / humidity double response as well as a preparation method and application of the intelligent modified atmosphere packaging film. The preparation method comprises the following steps: mixing thymol emulsion and graphene oxide dispersion liquid, and stirring and reacting at room temperature in a dark place to prepare graphene oxide-thymol; the preparation method comprises the following steps: dissolving chitosan in an acetic acid aqueous solution, then adding graphene oxide-thymol and a plasticizer, and carrying out ultrasonic dispersion treatment to form a film-forming solution; and carrying out film forming treatment on the film forming solution by adopting a casting method to prepare the intelligent modified atmosphere packaging film with gas selectivity and pH / humidity double response. The prepared intelligent modified atmosphere packaging film can be modified automatically, is uniform and stable in structure, high in encapsulation efficiency, close in coordination, good in antibacterial and antioxidant activity and excellent in mechanical property and gas barrier property, can realize selective adsorption of gas, controls release of thymol by responding to changes of the pH value and humidity in the environment, and has a good application prospect. The method has a good application prospect in the field of fruit and vegetable preservation.

The invention relates to an o / w type high-content composite essential oil nanoemulsion and a preparation method and application thereof.The median particle size of the composite essential oil nanoemulsion is not larger than 45 nm, and the composite essential oil nanoemulsion comprises plant essential oil, polyethylene glycol glycerol ricinoleate with the HLB value being 10-14, a cosolvent, water, vitamin E acetate and ethylene diamine tetraacetic acid disodium salt. The plant essential oil is selected from two or more of carvacrol, cinnamyl aldehyde, capsicum oleoresin and thymol. The compound essential oil nanoemulsion solves the key technical problem of high-content load compound nanoemulsion of various plant essential oils, is beneficial to exerting the synergistic effect of different essential oils, and reduces the addition amount of the essential oils while achieving the same physiological function. Besides, the particle size of the composite essential oil nanoemulsion reaches the nanoscale, the composite essential oil nanoemulsion can form homogeneous-phase clear liquid, can be quickly diffused in a waterline or a water environment, is more beneficial to absorption, has the advantages of good stability and long storage life, and is more competitive in practical application.

The invention discloses an anti-inflammatory and pain-relieving cataplasm capable of improving drug stability and a preparation method thereof, and belongs to the technical field of traditional Chinese medicines. The inflammation diminishing and pain relieving cataplasm is prepared from the following raw material components: methyl salicylate, eucalyptus oil, synthetic menthol, camphor, borneol, thymol, belladonna liquid extract, diphenhydramine hydrochloride, DL-tartaric acid, gelatin, titanium dioxide, PVP, sorbitol, beta-cyclodextrin, dihydroxyaluminum aminoacetate, castor oil, partially neutralized sodium polyacrylate, glycerol and purified water. Through process improvement and inclusion of volatile materials in the formula with beta-cyclodextrin, the prepared inflammation-diminishing and pain-relieving cataplasm has the characteristics of good stability and capability of remarkably improving in-vitro drug release.

The invention discloses a polyurethane coating and a preparation method thereof, and belongs to the technical field of antibacterial coatings. The preparation method of the polyurethane coating comprises the following steps: carrying out acyl chloride substitution reaction on a phenolic substance and a chlorine donor to obtain an intermediate reactant, and carrying out conjugate addition reaction on the intermediate reactant and an amine substance with hydroxyl groups at two ends to obtain antibacterial diol; reacting the antibacterial diol with isocyanate to obtain a polyurethane coating; the phenolic substance is selected from at least one of thymol, carvacrol, paeonol, catechol and theaflavin. The antibacterial coating is applied to the aspect of an antibacterial coating of a food contact part, the problem that the antibacterial property of an existing antibacterial coating is difficult to last is solved, and the antibacterial coating has the synergistic antibacterial effect of killing and defending bacteria.

The invention discloses fresh and wet sweet potato vermicelli and a preparation method thereof, the fresh and wet sweet potato vermicelli comprises the processing raw materials of sweet potato starch, domestic drinking water, an acidity regulator and a fresh-keeping preservative, the usage amount of the fresh-keeping preservative is 0.05-0.6% of the weight of the starch raw material, and the preparation method comprises the following steps: weighing the raw materials of the fresh and wet vermicelli, preparing starchy sauce, preparing dough, mixing slurry, curing and forming, and the like, thereby obtaining the fresh and wet sweet potato vermicelli. Aging the cured vermicelli for 1-2.5 hours in an environment of 10-1 DEG C, so as to obtain aged vermicelli; and cutting the aged vermicelli into strips, performing vacuum packaging, and performing pasteurization to obtain the product. In the preparation process of the fresh and wet sweet potato vermicelli, potassium cinnamate, thymol and aloe extract are added as fresh-keeping preservatives. The method overcomes the problem that chemical preservatives such as sodium dehydroacetate cannot be added into the fresh and wet sweet potato vermicelli, and prolongs the shelf life of the fresh and wet sweet potato vermicelli.

A preparation method of plant compound essential oil comprises the following steps: preparing mixed powder from dried lemon slices, mint and litsea coreana, carrying out carbon dioxide supercritical extraction, and collecting an extract; the preparation method comprises the following steps: dropwise adding a carboxymethyl-beta-cyclodextrin solution into a mixture of eugenol and thymol, carrying out ultrasonic treatment to obtain an ultrasonic mixed solution, standing, centrifuging, collecting supernate, and drying to obtain a white powdery inclusion compound; and adding lecithin, Tween 80, disodium pyrophosphate and deionized water into the extract, heating and stirring, continuing to add the inclusion compound, homogenizing to obtain a nano-emulsion, adding gelatin and propylene glycol, heating and preserving heat, and cooling to obtain the plant composite essential oil. The compound essential oil disclosed by the invention has antibacterial and antioxidant effects, and has relatively strong antibacterial ability on botrytis cinerea and penicillium germs, and the DPPH free radical scavenging rate is greater than or equal to 90%. According to the invention, the active ingredients of the essential oil are wrapped by carboxymethyl-beta-cyclodextrin and synergistically embedded by lipidosome through a nano-embedding technology to realize slow release, so that the antioxidant and antibacterial properties are effectively prolonged.

The present invention relates to a composition suitable for disinfecting surfaces which comprises contacting said formulation to an environmental surface wherein the formulation comprises thymol at a concentration ranging from at least 0.10% by weight and citric acid at a concentration from at least 0.3% by weight. Surprisingly and unexpectantly these concentrations provide formulations that are more effective in disinfecting than ones containing less of the two materials, or significantly more citric acid, or having just one of the two materials alone.

The invention relates to the technical field of fabrics, and discloses an antibacterial fabric and a preparation method thereof.The preparation method comprises the steps that water, an organosilicon quaternary ammonium salt thymol finishing agent and a cotton / spandex blended fabric are added into a container, and then two-time dipping and two-time rolling, pre-drying and baking are conducted; the organic silicon quaternary ammonium salt thymol finishing agent contains phenolic hydroxyl groups, quaternary ammonium salt cations, ureido and other hydrophilic groups, so that the finished fabric shows good moisture regain and hydrophilic hygroscopicity, and the organic silicon quaternary ammonium salt thymol finishing agent contains a thymol natural antibacterial agent and organic silicon quaternary ammonium salt antibacterial groups, so that the antibacterial effect of the fabric is improved. The strong killing and inhibiting effects on bacteria and microorganisms are realized. The finishing agent is firmly attached to the surface of the fabric, so that the fabric is endowed with excellent antibacterial performance.

Methods of making bioactive compound-loaded nanoparticles are provided. The methods harness naturally-occurring biopolymers to produce nanoparticles from raw plant materials. Methods include contacting plant-derived materials with alkaline solution with agitation to deprotonate the bioactive materials and biopolymers to form nanoparticles. In some forms, the methods contact the nanoparticle with an acid to re-protonate the components and more stable nanoparticles. The bioactive compounds can be extracted from raw plants and / or plant parts, including turmeric, ginger, clove, thyme, pepper, and rosemary. The bioactive compounds include curcumin, gingerols, shogaols, eugenol, thymol, carvacrol, capsaicin, and rosmarinic acid. Compositions and formulations containing bioactive-compound loaded nanoparticles are also provided.

The invention relates to the technical field of packaging materials, and discloses a preparation method of an antibacterial and antiseptic food packaging material, and the antibacterial and antiseptic food packaging material comprises 100 parts by weight of polyvinyl alcohol, 2-15 parts by weight of cross-linked beta-cyclodextrin included thyme oil, and 1-1.5 parts by weight of glycerol. The hyperbranched polymer cross-linked beta-cyclodextrin contains a three-dimensional hyperbranched dendritic molecular chain and has a higher inclusion amount for thyme oil, so that more active antibacterial components such as thymol and carvacrol are included, and the antibacterial and anticorrosive properties of the packaging material are remarkably improved after the hyperbranched polymer cross-linked beta-cyclodextrin is added into the polyvinyl alcohol film packaging material. The hyperbranched polymer cross-linked beta-cyclodextrin contains a flexible polyether hyperbranched molecular chain, has a certain toughening effect on polyvinyl alcohol, and is beneficial to improving the elongation at break and toughness of the polyvinyl alcohol film packaging material.

The present invention relates to a biopesticidal composition comprising combination of elemental sulphur and at least one biochemical pesticide selected from thymol and eugenol or their derivatives. The invention particularly relates to a biopesticidal composition comprising elemental sulphur in the range of 1% w / w to 90% w / w of the total composition; at least one biochemical pesticide in the range of 0.1% w / w to 30% w / w of the total composition wherein the biochemical pesticide is selected from thymol and eugenol or their derivatives; and at least one agriculturally acceptable excipient in the range of 5% w / w to 98% w / w of the total composition. The composition has particles in the size range of 0.1 micron to 50 microns. The present invention also relates to a method for protecting the plant against pests or diseases by treatment of plant, plant propagation material, locus, parts thereof or the surrounding soil with a biopesticidal composition comprising of an effective amount of elemental sulphur; an effective amount of at least one biochemical pesticide selected from thymol and eugenol or their derivatives and at least one agriculturally acceptable excipient.

The invention provides a thymol derivative as well as a preparation method and application thereof, and relates to the technical field of biological medicines. The preparation method comprises the following steps: carrying out esterification reaction on thymol and indole-3-carboxylic acid to prepare a thymol derivative, namely 2-isopropyl-5-methyl phenyl 1H-indole-3-carboxylic ester. Under the process conditions provided by the invention, the yield of the thymol derivative can reach 93-94%. The anti-coccidiosis index of the thymol derivative is as high as 196.51, and the thymol derivative can obviously reduce the influence of chicken coccidiosis on the weight of chicken, has a remarkable effect of promoting the growth and development of the body, and can obviously improve the clinical symptoms of chicken infected with coccidiosis, recover the mental condition and appetite of sick chicken, obviously reduce the occurrence of bloody stool and improve the intestinal tract lesion condition; the anti-coccidiosis effect of the thymol derivative provided by the invention is obvious and is obviously better than that of thymol, and the thymol derivative is expected to become a new veterinary drug for treating chicken coccidiosis infection.

To provide a sebum secretion-inhibiting composition containing, as an effective ingredient, 3, 4, 5-trimethoxycinnamate thymol ester, or a stereoisomer, pharmaceutically acceptable salt, hydrate or solvate thereof.SOLUTION: The disclosed compositions can inhibit sebum secretion of skin or scalp exerting useful effects such as prevention or amelioration of seborrheic dermatitis, seborrheic scalp inflammation, prevention or amelioration of acne, or pore-shrinking.SELECTED DRAWING: Figure 1

The invention relates to the field of alkane volatile organic compound absorption treatment, and discloses an alkane volatile organic compound absorbent, a preparation method and application thereof, and a method for removing alkane volatile organic compounds. The absorbent contains a hydrogen bond acceptor, a hydrogen bond donor and a composite component in a molar ratio of 1: (1-4): (0.01-0.1), wherein the hydrogen bond donor is selected from at least one of C12-18 saturated fatty acid and C12-18 monounsaturated fatty acid; the hydrogen bond receptor is selected from at least one of menthol, thymol and lidocaine; the composite component is a combination of a component A and a component B; the absorbent provided by the invention has the characteristics of low volatility, good stability and simple preparation process, and particularly has high absorption efficiency on C2-C4 alkanes.

The invention discloses an application of a soybean protein-thymol nano-composite in the aspect of removing marine fouling algae. According to the invention, the excellent nano-delivery function of the SPI is utilized, insoluble thymol is loaded on SPI particles through hydrophobic interaction to form a nano-composite, the water solubility is greatly improved after the thymol is combined with the SPI, and the thymol can be more sufficiently and quickly dispersed in water, so that the stability of the nano-composite is improved, and the stability of the nano-composite is improved. Therefore, the thymol is in full contact with the target algae in the form of nano particles, so that the growth and spreading of marine fouling algae can be quickly and effectively controlled, and the effect of removing the algae is achieved.

The invention relates to a method for purifying a by-product of neomenthol in a menthol production line, which is characterized in that a reaction product obtained by hydrogenating thymol to produce menthol is used as a raw material, and the extraction of high-purity neomenthol is realized through a process of combining rectification and crystallization. The method specifically comprises the following steps: rectifying by using a rectifying tower with a specific specification under the conditions that the temperature is 115-125 DEG C, the vacuum degree is 15-20mmHg and the reflux ratio is (20: 2)-(50: 2), and enriching neomenthol to 75-77%; and carrying out plate-type crystallization treatment twice, carrying out crystallization under the conditions that the temperature is reduced to 25-27 DEG C through primary crystallization and the temperature is reduced to 35 DEG C through secondary programmed cooling, and carrying out further purification through heating and sweating to finally obtain a neomenthol product with the purity of 99.5%. The method is simple in process and low in energy consumption, does not need a solvent, can be directly connected with an existing production line, and is suitable for large-scale production of medicine and spice-grade high-purity neomenthol.

The present invention relates to a composition suitable for disinfecting surfaces which comprises contacting said formulation to an environmental surface wherein the formulation comprises thymol at a concentration ranging from at least 0.10% by weight and citric acid at a concentration from at least 0.3% by weight. Surprisingly and unexpectantly these concentrations provide formulations that are more effective in disinfecting than ones containing less of the two materials, or significantly more citric acid, or having ju

This invention provides a broad-spectrum antibacterial natural active ingredient nanoemulsion, its preparation method, and its application, relating to the field of food preservation technology. The preparation method of the broad-spectrum antibacterial natural active ingredient nanoemulsion provided by this invention includes the following steps: mixing soy protein isolate and citrate buffer to obtain an aqueous phase solution; mixing thymol, eugenol, ginger essential oil, spearmint oil, and soybean oil to obtain an oil phase solution; mixing the aqueous and oil phase solutions and performing shearing treatment to obtain a crude emulsion; and subjecting the crude emulsion to ultrasonic disruption to obtain the broad-spectrum antibacterial natural active ingredient nanoemulsion. This invention can improve the stability and water solubility of active ingredients such as eugenol, thymol, carvone, limonene, and α-soybeanene, improve their antibacterial properties, and effectively extend the shelf life of refrigerated prepared meat products.

The invention provides a nano-emulsion for preventing and treating porcine respiratory diseases and a preparation method of the nano-emulsion, and belongs to the field of preparation of nano-emulsion preparations. The nano-emulsion comprises an outer water phase, and a first water-in-oil emulsion core, a second water-in-oil emulsion core, a third water-in-oil emulsion core and a fourth water-in-oil emulsion core which are dispersed in the outer water phase, wherein oil phases of the first water-in-oil emulsion core and the second water-in-oil emulsion core comprise eucalyptus globulus oil and peppermint oil; the D90 particle size of the inner water phase of the first water-in-oil emulsion core is between 100nm and 150nm; the D90 particle size of the inner water phase of the second water-in-oil emulsion core is between 250 nm and 300 nm; oil phases of the third water-in-oil emulsion core and the fourth water-in-oil emulsion core comprise carvacrol and thymol; the D90 particle size of the inner water phase of the third water-in-oil emulsion core is 200-300 nm; and the D90 particle size of the inner water phase of the fourth water-in-oil emulsion core is 500-700nm. The nano-emulsion has long drug effect and long-term stability.

The present invention discloses a recombinant bacterium for synthesizing key components of plant essential oil, a construction method thereof and applications. The recombinant bacterium contains exogenous genes; the exogenous genes include genes of terpene synthase, cytochrome P450 and short-chain dehydrogenase; the key components of the plant essential oil include thymol and carvacrol. By introducing the genes of terpene synthase, cytochrome P450 and short-chain dehydrogenase, the present invention successfully constructs a recombinant bacterium capable of synthesizing thymol and carvacrol, realizing the heterologous synthesis of thymol derivatives. Moreover, by using the recombinant bacterium of the present invention to transform and produce thymol and carvacrol, the production efficiency is high, it is green and environmentally friendly, and the cost is low, having good industrial application prospects.

The present application belongs to the technical field of pesticides, and particularly relates to a fungicide composition for preventing and treating vine gummy stem blight. The fungicide composition for preventing and treating vine gummy stem blight is prepared by compounding thymol with monensin sodium or physcion methyl ether as effective components. The fungicide composition of the present application has different fungicidal mechanisms of thymol, monensin sodium and physcion methyl ether, and the combination of the three components can delay the accumulation and development of pathogenic fungi resistance, and effectively overcome the problems existing in the prevention and treatment of vine gummy stem blight by using single-component pesticides. In addition, the effective components of the fungicide composition of the present application have a synergistic effect on vine gummy stem blight, can improve the prevention and treatment effect on vine gummy stem blight, help to reduce the application dose of the pesticide, and effectively overcome the problems of pesticide residue exceeding the standard and environmental pollution. Furthermore, thymol, monensin sodium and physcion methyl ether in the fungicide composition of the present application are environmentally friendly and green.

The invention discloses a method for extracting and separating baicalin and baicalein, which comprises the following steps: S1, weighing thymol and menthol, adding the thymol and the menthol into a three-neck flask, and heating and stirring to form uniform and transparent liquid as an extracting agent thymol-menthol eutectic solvent; s2, mixing the radix scutellariae powder with a 50% ethanol solution, heating, condensing and refluxing twice to obtain an extracting solution, centrifuging, taking supernate, and concentrating to obtain a radix scutellariae extracting solution. And S3, putting the scutellaria baicalensis extracting solution and an extracting agent into a high-pressure extraction kettle, carrying out pressurized extraction, transferring to a separating funnel, standing for layering, and respectively collecting. And S4, adding water into the lower-layer water phase for dilution, filtering, heating and stirring, standing at low temperature for crystallization, carrying out suction filtration, washing and drying to obtain purified baicalin. And S5, adding ethyl acetate into the upper-layer extraction phase, oscillating and standing, collecting the lower-layer ethyl acetate, adding anhydrous sodium sulfate, filtering, concentrating, adding absolute methanol, standing at low temperature, crystallizing, carrying out suction filtration, washing and drying to obtain purified baicalein. According to the method for extracting and separating the baicalin and the baicalein, the yield and the purity of the baicalin and the baicalein can be improved.

The invention relates to a preparation method of an animal anti-diarrhea feed additive containing delinted moxa powder and essential oil. The preparation method of the animal anti-diarrhea feed additive containing the delinted moxa powder and the essential oil comprises the following steps: mixing essential oil components thymol and cinnamyl aldehyde, and stirring at 35-65 DEG C until the essential oil components are dissolved to obtain an essential oil solution; the preparation method comprises the following steps: mixing antioxidants BHA and PG, citric acid and ethanol, and stirring until dissolving to obtain an ethanol solution; mixing the ethanol solution with stone powder, and drying to remove ethanol to obtain a solid mixture; mixing the solid mixture with the essential oil solution, adding delinted moxa powder, and stirring uniformly; according to the preparation method of the animal anti-diarrhea feed additive containing the delinted moxa powder and the essential oil, stable combination of the essential oil and the delinted moxa powder is achieved, the diarrhea morbidity and mortality are remarkably reduced in animal experiments, and the effect is better than that of independent use of the essential oil.

The present invention relates to the technical field of packaging materials, and discloses a preparation method of an antibacterial and antiseptic food packaging material, the antibacterial and antiseptic food packaging material includes 100 parts by weight of polyvinyl alcohol, 2-15 parts by weight of cross-linked β-cyclodextrin inclusion thyme oil, and 1-1.5 parts by weight of propylene glycol. The hyperbranched polymer cross-linked β-cyclodextrin of the present invention contains a three-dimensional hyperbranched dendritic molecular chain, has a higher inclusion amount for thyme oil, thereby including more active ingredients such as thymol and carvacrol, and is added to the polyvinyl alcohol film packaging material, significantly improving the antibacterial and antiseptic properties of the packaging material. The hyperbranched polymer cross-linked β-cyclodextrin contains a flexible polyether hyperbranched molecular chain, which has a certain toughening effect on polyvinyl alcohol, and is conducive to improving the elongation at break and the toughness of the polyvinyl alcohol film packaging material.

The present application belongs to the technical field of livestock feed additives, and discloses a compound plant extract additive for resisting and promoting growth of feed and a preparation method thereof. The additive is composed of not less than 40% of the compound plant extract and not less than 5% of the compound essential oil. The plant extract is selected from the group consisting of Rhizoma Coptidis, Radix Aucklandiae, Radix Scrophulariae, roasted foxtail millet, leaves of Alchornea trewioides, moxa licorice and Amomum kravanh as raw materials; the essential oil part includes cinnamaldehyde, cassia oil, cinnamon oil, thymol and oregano oil to form a synergistic antibacterial aromatic system. The starch-arabic gum protein composite wall material is used for microencapsulation to realize slow release and adapt to the feed granulation condition. The bitterness and irritating odor are covered by the flavoring technology to improve the animal feed intake and palatability. The additive has multiple functions of resisting and preventing diarrhea, enhancing immunity, promoting growth and improving meat quality, is natural in origin, free of antibiotics, and has no residue and no drug resistance, and is suitable for long-term feeding.

Provided are a cosurfactant-free microemulsion encapsulating glycyrrhetinic acid, a preparation method therefor, and use thereof. The cosurfactant-free microemulsion comprises carvacrol / thymol, a fatty acid, a nonionic surfactant, and water. Based on the mass percentage of the raw materials, the glycyrrhetinic acid accounts for 0.1-5%, the carvacrol / thymol accounts for 0.1-5%, the fatty acid accounts for 0.1-10%, the nonionic surfactant accounts for 1-30%, and the balance is made up to 100% with water. Carvacrol / thymol not only increases the solubility of glycyrrhetinic acid, but also promotes the transdermal absorption of glycyrrhetinic acid, and is a cosmetic composite efficacy composition having antioxidant, anti-inflammatory, and antibacterial effects.

The invention provides an oral care composition for inhibiting helicobacter pylori and a preparation method of the oral care composition. The oral care composition comprises glycerin, xylitol, erythritol, thymol clathrate, garlic extract clathrate, propolis extract, lactoferrin, disodium ethylene diamine tetraacetate, menthol, potassium sorbate and purified water. The thymol clathrate compound is obtained by carrying out clathration on thymol through beta-cyclodextrin. The garlic extract clathrate compound is obtained by clathrating a garlic extract with beta-cyclodextrin. According to the oral care composition provided by the invention, the helicobacter pylori in the oral cavity can be effectively inhibited through reasonable proportioning of various components, so that the risks of ozostomia and stomach reinfection are reduced.

The invention relates to the technical field of medicinal chemistry, and discloses a thymol derivative as well as a preparation method and application thereof. The thymol ethyl, propyl, butyl azole and piperazine derivative provided by the invention is used as a bacteriostatic agent for resisting phytopathogen and is used for preparing pesticides; the prepared pesticide can be used for preventing and treating plant diseases such as cucumber damping-off, rice damping-off, cotton damping-off, watermelon damping-off, sclerotinia rot of colza, botrytis cinerea, cucumber gray mold, grape gray mold, wheat scab, rice blast, wheat sharp eyespot, wheat stem rot, sweet potato soft rot and lily wilt.