117 results about "Thymol" patented technology

The invention relates to the technical field of coatings, in particular to a corrosion-resistant coating material and a preparation method thereof. The corrosion-resistant coating material comprises the following components in parts by mass: 80-100 parts of epoxy resin, 5-20 parts of a modified phenolic aldehyde amine curing agent, 2-5 parts of a waterproof agent, 5-10 parts of a corrosion inhibitor and 40-55 parts of a lubricant. The modified phenolic aldehyde amine curing agent is obtained by carrying out Mannich reaction on phenol, thymol, aliphatic polyamine and formaldehyde. The phenol provides a rigid benzene ring structure, and endows a cured product with good heat resistance and chemical resistance. Thymol improves the flexibility and adhesive force of the cured product and enhances the hydrophobicity of the cured product at the same time. The epoxy resin and the modified phenolic aldehyde amine curing agent are polymerized, the waterproof agent, the corrosion inhibitor and the lubricant are wrapped, and the obtained coating material has good adhesive force and corrosion resistance.

The invention provides a tropical fruit preservative film which is of a double-layer structure, the outer layer is a moisture-resistant antibacterial layer, and the inner layer is a water-absorbing antifogging antibacterial layer; and the water-absorbing anti-fog antibacterial layer also comprises a pH sensitive microcapsule. The outer layer is prepared from polyhydroxyalkanoate, a humidity sensitive type block copolymer and CuO / SiO2 antibacterial nano-enzyme; and the water-absorbing anti-fog antibacterial layer comprises polyhydroxyalkanoate, a humidity-sensitive block copolymer, hygroscopic zeolite, thymol, gallic acid and a pH-sensitive microcapsule. The preservative film has a certain hydrophobic effect, the humidity of a packaging microenvironment can be adjusted, breeding of putrefying bacteria can be inhibited, meanwhile, thymol and gallic acid form a slow-release antibacterial system, and tropical fruits keep good quality in the storage and transportation links through cooperation of all the components; besides, the pH sensitive microcapsules can respond to acidic substances generated by corruption in real time, help merchants to quickly sort deteriorated fruits, and provide a visual judgment basis for consumers at the same time.

The invention discloses an intelligent modified atmosphere packaging film with gas selectivity and pH / humidity double response as well as a preparation method and application of the intelligent modified atmosphere packaging film. The preparation method comprises the following steps: mixing thymol emulsion and graphene oxide dispersion liquid, and stirring and reacting at room temperature in a dark place to prepare graphene oxide-thymol; the preparation method comprises the following steps: dissolving chitosan in an acetic acid aqueous solution, then adding graphene oxide-thymol and a plasticizer, and carrying out ultrasonic dispersion treatment to form a film-forming solution; and carrying out film forming treatment on the film forming solution by adopting a casting method to prepare the intelligent modified atmosphere packaging film with gas selectivity and pH / humidity double response. The prepared intelligent modified atmosphere packaging film can be modified automatically, is uniform and stable in structure, high in encapsulation efficiency, close in coordination, good in antibacterial and antioxidant activity and excellent in mechanical property and gas barrier property, can realize selective adsorption of gas, controls release of thymol by responding to changes of the pH value and humidity in the environment, and has a good application prospect. The method has a good application prospect in the field of fruit and vegetable preservation.

The present invention relates to a composition suitable for disinfecting surfaces which comprises contacting said formulation to an environmental surface wherein the formulation comprises thymol at a concentration ranging from at least 0.10% by weight and citric acid at a concentration from at least 0.3% by weight. Surprisingly and unexpectantly these concentrations provide formulations that are more effective in disinfecting than ones containing less of the two materials, or significantly more citric acid, or having just one of the two materials alone.

Methods of making bioactive compound-loaded nanoparticles are provided. The methods harness naturally-occurring biopolymers to produce nanoparticles from raw plant materials. Methods include contacting plant-derived materials with alkaline solution with agitation to deprotonate the bioactive materials and biopolymers to form nanoparticles. In some forms, the methods contact the nanoparticle with an acid to re-protonate the components and more stable nanoparticles. The bioactive compounds can be extracted from raw plants and / or plant parts, including turmeric, ginger, clove, thyme, pepper, and rosemary. The bioactive compounds include curcumin, gingerols, shogaols, eugenol, thymol, carvacrol, capsaicin, and rosmarinic acid. Compositions and formulations containing bioactive-compound loaded nanoparticles are also provided.

The present invention relates to a biopesticidal composition comprising combination of elemental sulphur and at least one biochemical pesticide selected from thymol and eugenol or their derivatives. The invention particularly relates to a biopesticidal composition comprising elemental sulphur in the range of 1% w / w to 90% w / w of the total composition; at least one biochemical pesticide in the range of 0.1% w / w to 30% w / w of the total composition wherein the biochemical pesticide is selected from thymol and eugenol or their derivatives; and at least one agriculturally acceptable excipient in the range of 5% w / w to 98% w / w of the total composition. The composition has particles in the size range of 0.1 micron to 50 microns. The present invention also relates to a method for protecting the plant against pests or diseases by treatment of plant, plant propagation material, locus, parts thereof or the surrounding soil with a biopesticidal composition comprising of an effective amount of elemental sulphur; an effective amount of at least one biochemical pesticide selected from thymol and eugenol or their derivatives and at least one agriculturally acceptable excipient.

To provide a sebum secretion-inhibiting composition containing, as an effective ingredient, 3, 4, 5-trimethoxycinnamate thymol ester, or a stereoisomer, pharmaceutically acceptable salt, hydrate or solvate thereof.SOLUTION: The disclosed compositions can inhibit sebum secretion of skin or scalp exerting useful effects such as prevention or amelioration of seborrheic dermatitis, seborrheic scalp inflammation, prevention or amelioration of acne, or pore-shrinking.SELECTED DRAWING: Figure 1

The invention relates to a method for purifying a by-product of neomenthol in a menthol production line, which is characterized in that a reaction product obtained by hydrogenating thymol to produce menthol is used as a raw material, and the extraction of high-purity neomenthol is realized through a process of combining rectification and crystallization. The method specifically comprises the following steps: rectifying by using a rectifying tower with a specific specification under the conditions that the temperature is 115-125 DEG C, the vacuum degree is 15-20mmHg and the reflux ratio is (20: 2)-(50: 2), and enriching neomenthol to 75-77%; and carrying out plate-type crystallization treatment twice, carrying out crystallization under the conditions that the temperature is reduced to 25-27 DEG C through primary crystallization and the temperature is reduced to 35 DEG C through secondary programmed cooling, and carrying out further purification through heating and sweating to finally obtain a neomenthol product with the purity of 99.5%. The method is simple in process and low in energy consumption, does not need a solvent, can be directly connected with an existing production line, and is suitable for large-scale production of medicine and spice-grade high-purity neomenthol.

The present invention relates to a composition suitable for disinfecting surfaces which comprises contacting said formulation to an environmental surface wherein the formulation comprises thymol at a concentration ranging from at least 0.10% by weight and citric acid at a concentration from at least 0.3% by weight. Surprisingly and unexpectantly these concentrations provide formulations that are more effective in disinfecting than ones containing less of the two materials, or significantly more citric acid, or having ju

This invention provides a broad-spectrum antibacterial natural active ingredient nanoemulsion, its preparation method, and its application, relating to the field of food preservation technology. The preparation method of the broad-spectrum antibacterial natural active ingredient nanoemulsion provided by this invention includes the following steps: mixing soy protein isolate and citrate buffer to obtain an aqueous phase solution; mixing thymol, eugenol, ginger essential oil, spearmint oil, and soybean oil to obtain an oil phase solution; mixing the aqueous and oil phase solutions and performing shearing treatment to obtain a crude emulsion; and subjecting the crude emulsion to ultrasonic disruption to obtain the broad-spectrum antibacterial natural active ingredient nanoemulsion. This invention can improve the stability and water solubility of active ingredients such as eugenol, thymol, carvone, limonene, and α-soybeanene, improve their antibacterial properties, and effectively extend the shelf life of refrigerated prepared meat products.

The present application belongs to the technical field of pesticides, and particularly relates to a fungicide composition for preventing and treating vine gummy stem blight. The fungicide composition for preventing and treating vine gummy stem blight is prepared by compounding thymol with monensin sodium or physcion methyl ether as effective components. The fungicide composition of the present application has different fungicidal mechanisms of thymol, monensin sodium and physcion methyl ether, and the combination of the three components can delay the accumulation and development of pathogenic fungi resistance, and effectively overcome the problems existing in the prevention and treatment of vine gummy stem blight by using single-component pesticides. In addition, the effective components of the fungicide composition of the present application have a synergistic effect on vine gummy stem blight, can improve the prevention and treatment effect on vine gummy stem blight, help to reduce the application dose of the pesticide, and effectively overcome the problems of pesticide residue exceeding the standard and environmental pollution. Furthermore, thymol, monensin sodium and physcion methyl ether in the fungicide composition of the present application are environmentally friendly and green.

The invention discloses a method for extracting and separating baicalin and baicalein, which comprises the following steps: S1, weighing thymol and menthol, adding the thymol and the menthol into a three-neck flask, and heating and stirring to form uniform and transparent liquid as an extracting agent thymol-menthol eutectic solvent; s2, mixing the radix scutellariae powder with a 50% ethanol solution, heating, condensing and refluxing twice to obtain an extracting solution, centrifuging, taking supernate, and concentrating to obtain a radix scutellariae extracting solution. And S3, putting the scutellaria baicalensis extracting solution and an extracting agent into a high-pressure extraction kettle, carrying out pressurized extraction, transferring to a separating funnel, standing for layering, and respectively collecting. And S4, adding water into the lower-layer water phase for dilution, filtering, heating and stirring, standing at low temperature for crystallization, carrying out suction filtration, washing and drying to obtain purified baicalin. And S5, adding ethyl acetate into the upper-layer extraction phase, oscillating and standing, collecting the lower-layer ethyl acetate, adding anhydrous sodium sulfate, filtering, concentrating, adding absolute methanol, standing at low temperature, crystallizing, carrying out suction filtration, washing and drying to obtain purified baicalein. According to the method for extracting and separating the baicalin and the baicalein, the yield and the purity of the baicalin and the baicalein can be improved.

The invention relates to a preparation method of an animal anti-diarrhea feed additive containing delinted moxa powder and essential oil. The preparation method of the animal anti-diarrhea feed additive containing the delinted moxa powder and the essential oil comprises the following steps: mixing essential oil components thymol and cinnamyl aldehyde, and stirring at 35-65 DEG C until the essential oil components are dissolved to obtain an essential oil solution; the preparation method comprises the following steps: mixing antioxidants BHA and PG, citric acid and ethanol, and stirring until dissolving to obtain an ethanol solution; mixing the ethanol solution with stone powder, and drying to remove ethanol to obtain a solid mixture; mixing the solid mixture with the essential oil solution, adding delinted moxa powder, and stirring uniformly; according to the preparation method of the animal anti-diarrhea feed additive containing the delinted moxa powder and the essential oil, stable combination of the essential oil and the delinted moxa powder is achieved, the diarrhea morbidity and mortality are remarkably reduced in animal experiments, and the effect is better than that of independent use of the essential oil.

The present invention relates to the technical field of packaging materials, and discloses a preparation method of an antibacterial and antiseptic food packaging material, the antibacterial and antiseptic food packaging material includes 100 parts by weight of polyvinyl alcohol, 2-15 parts by weight of cross-linked β-cyclodextrin inclusion thyme oil, and 1-1.5 parts by weight of propylene glycol. The hyperbranched polymer cross-linked β-cyclodextrin of the present invention contains a three-dimensional hyperbranched dendritic molecular chain, has a higher inclusion amount for thyme oil, thereby including more active ingredients such as thymol and carvacrol, and is added to the polyvinyl alcohol film packaging material, significantly improving the antibacterial and antiseptic properties of the packaging material. The hyperbranched polymer cross-linked β-cyclodextrin contains a flexible polyether hyperbranched molecular chain, which has a certain toughening effect on polyvinyl alcohol, and is conducive to improving the elongation at break and the toughness of the polyvinyl alcohol film packaging material.

The present application belongs to the technical field of livestock feed additives, and discloses a compound plant extract additive for resisting and promoting growth of feed and a preparation method thereof. The additive is composed of not less than 40% of the compound plant extract and not less than 5% of the compound essential oil. The plant extract is selected from the group consisting of Rhizoma Coptidis, Radix Aucklandiae, Radix Scrophulariae, roasted foxtail millet, leaves of Alchornea trewioides, moxa licorice and Amomum kravanh as raw materials; the essential oil part includes cinnamaldehyde, cassia oil, cinnamon oil, thymol and oregano oil to form a synergistic antibacterial aromatic system. The starch-arabic gum protein composite wall material is used for microencapsulation to realize slow release and adapt to the feed granulation condition. The bitterness and irritating odor are covered by the flavoring technology to improve the animal feed intake and palatability. The additive has multiple functions of resisting and preventing diarrhea, enhancing immunity, promoting growth and improving meat quality, is natural in origin, free of antibiotics, and has no residue and no drug resistance, and is suitable for long-term feeding.

Provided are a cosurfactant-free microemulsion encapsulating glycyrrhetinic acid, a preparation method therefor, and use thereof. The cosurfactant-free microemulsion comprises carvacrol / thymol, a fatty acid, a nonionic surfactant, and water. Based on the mass percentage of the raw materials, the glycyrrhetinic acid accounts for 0.1-5%, the carvacrol / thymol accounts for 0.1-5%, the fatty acid accounts for 0.1-10%, the nonionic surfactant accounts for 1-30%, and the balance is made up to 100% with water. Carvacrol / thymol not only increases the solubility of glycyrrhetinic acid, but also promotes the transdermal absorption of glycyrrhetinic acid, and is a cosmetic composite efficacy composition having antioxidant, anti-inflammatory, and antibacterial effects.

The invention provides an oral care composition for inhibiting helicobacter pylori and a preparation method of the oral care composition. The oral care composition comprises glycerin, xylitol, erythritol, thymol clathrate, garlic extract clathrate, propolis extract, lactoferrin, disodium ethylene diamine tetraacetate, menthol, potassium sorbate and purified water. The thymol clathrate compound is obtained by carrying out clathration on thymol through beta-cyclodextrin. The garlic extract clathrate compound is obtained by clathrating a garlic extract with beta-cyclodextrin. According to the oral care composition provided by the invention, the helicobacter pylori in the oral cavity can be effectively inhibited through reasonable proportioning of various components, so that the risks of ozostomia and stomach reinfection are reduced.

The invention relates to the technical field of medicinal chemistry, and discloses a thymol derivative as well as a preparation method and application thereof. The thymol ethyl, propyl, butyl azole and piperazine derivative provided by the invention is used as a bacteriostatic agent for resisting phytopathogen and is used for preparing pesticides; the prepared pesticide can be used for preventing and treating plant diseases such as cucumber damping-off, rice damping-off, cotton damping-off, watermelon damping-off, sclerotinia rot of colza, botrytis cinerea, cucumber gray mold, grape gray mold, wheat scab, rice blast, wheat sharp eyespot, wheat stem rot, sweet potato soft rot and lily wilt.

The present application provides a kind of compound composition for preventing and treating plant wilt, the composition composition includes 4-hydroxy cinnamic acid and thymol, mass ratio is 1:1~1:2;The mass ratio of the composition is 1:1, the concentration of the composition is 60~300 μg / mL;The mass ratio of the composition is 1:2, the concentration of the composition is 50~200 μg / mL;The present application can inhibit the growth of pepper fusarium oxysporum f.sp.cubense mycelium, spore germination and sporulation, and can play a synergistic effect.The composition in the present application can significantly reduce the incidence of wilt in pot experiment.Compared with the prior art, the present application aims to reduce the use of chemical pesticides by low-cost, safe and efficient plant-derived antibacterial compounds.

The invention relates to a bactericidal composition containing bupirimate and thymol. The bactericidal composition comprises effective components of bupirimate and thymol which are subjected to binary compounding, wherein the mass ratio of bupirimate to thymol is (1-20): (30-5), the mass fraction ratio of bupirimate to thymol in the preparation is 6%-50%, the synergist is organic silicon and compound sodium nitrophenolate, and the balance is auxiliary components which are allowed to be used and accepted in pesticides. The dosage form of the bactericidal composition is missible oil, a suspending agent, wettable powder, an emulsion in water, a microemulsion and a microcapsule. The bactericidal composition is suitable for preventing and treating various powdery mildew, leaf spot, epidemic diseases and anthracnose of ornamental plants such as fruit trees, vegetables, flowers and the like and field crops, and especially has a very good protection and treatment effect on powdery mildew of apples and strawberries.

The application specifically relates to a polycyclic aromatic hydrocarbon detection method based on deep eutectic solvent extraction. DL The application provides a deep eutectic solvent composed of menthol and thymol, and provides application of the deep eutectic solvent as an extractant in the field of detection of four polycyclic aromatic hydrocarbons. The main innovation point of the detection method provided by the application lies in establishment of a sample pretreatment method. In the detection method finally provided by the application, the reagents mainly include acetonitrile, salt, menthol and thymol, the components are non-toxic and economical in cost, and high-sensitivity, high-accuracy, green and environment-friendly determination of trace and ultratrace PAH4 in special medical food is achieved.

The present application relates to the technical field of plant essential oil, and particularly discloses an essential oil composition and application thereof.The essential oil composition comprises the following components: carvacrol, thymol, lemon oil, peppermint oil, bay leaf oil, patchouli oil, geranium oil, perilla oil, cinnamon oil, clove oil and boldo oil.The essential oil composition provided by the present application is natural, environment-friendly, has good sterilization effect, comfortable smell, no obvious skin irritation, harmless to human body, and friendly to the environment, and can be applied to the preparation of antimicrobial products.

The invention relates to a method for purifying a byproduct menthone in a menthol production line. Aiming at a byproduct menthone generated in a process of producing menthol through thymol hydrogenation, the method comprises the following steps: rectifying a reaction product at a tower top temperature of 90 DEG C, a tower kettle temperature of 140 DEG C and a vacuum degree of-94.4 kPa, and extracting an enriched mixture of new menthol and menthone as a raw material; heating the raw materials to 50 DEG C for dissolving, cooling to 35-38 DEG C, and stirring for 30-60 minutes; adding 0.5-1g of seed crystal, carrying out programmed temperature control for 3-5h, cooling to 25-27 DEG C, carrying out heat preservation for 1-2h, and carrying out centrifugal separation on the crystal and a mother solution; the mother liquor is put into a rectifying tower, the column height is 140 cm, the inner diameter is 30 mm, a west tower ring filler is 3 mm * 3 mm, the kettle temperature is controlled to be 120-135 DEG C, the vacuum degree is 15-20 mmHg, the reflux ratio is 20: 2-50: 2, and qualified menthone is extracted. Through combination of crystallization enrichment and rectification, menthone in the menthol production by-product is directly purified, the problems of complex process, high cost and by-product waste of a traditional synthesis method are solved, and efficient utilization of resources is realized.

The invention discloses a novel application of thymol for preventing and treating soil-borne diseases caused by fusarium oxysporum, and belongs to the technical field of biopesticides. According to the embodiment of the invention, the action mechanism of the thymol on the fusarium oxysporum is analyzed by measuring the sensitivity of the thymol on the fusarium oxysporum and the influence of treatment with different concentrations on physiological and biochemical indexes such as hyphae, spores, proteins, DNA (Deoxyribonucleic Acid) and ergosterol contents of pathogenic bacteria and the yield of the oxytoxin; and a theoretical basis is provided for research and development of a novel biopesticide dosage form, namely thymol.

This invention discloses a method for preparing and applying nanoliposomes, relating to the fields of kiwifruit soft rot control and kiwifruit preservation. The preparation method includes the following steps: mixing thymol, cholesterol, and oleic acid to obtain an oil phase; mixing polyethylene glycol, lauryl ether phosphate, an emulsifying dispersant, and water to obtain an aqueous phase; mixing the oil phase and the aqueous phase, performing high-speed emulsification and shearing followed by low-speed stirring to obtain nanoliposomes. This invention uses cholesterol and oleic acid as wall materials and polyethylene glycol as a modifying material to successfully load thymol into nanoliposomes via microemulsification, achieving highly efficient encapsulation of thymol. The obtained thymol-containing nanoliposomes exhibit excellent performance and can be used to prepare formulations for controlling kiwifruit soft rot, demonstrating excellent control effects against the disease.

The application discloses a method and system for preparing thymol from m-p-isopropyl phenol / m-p-propyl phenol, wherein the m-p-isopropyl phenol / m-p-propyl phenol mixture is added into a reactor with a catalyst, and a reaction is carried out at a certain temperature; in the reaction, the m-p-isopropyl phenol and the like are subjected to a depropylation reaction to obtain a mixture of phenol and propylene; the reaction is completed under the control of a special online automatic analyzer; the mixture is cooled to a certain temperature; the propylene generated in the reaction is pressurized and stored in a spherical tank; an alkylation catalyst, a mixture of low-grade phenol and m-cresol are added into another reactor to carry out an alkylation reaction of phenol and propylene; and the reaction liquid is subjected to rectification to obtain high-purity phenol, high-purity m-cresol, o-isopropyl phenol, p-isopropyl phenol, 2-isopropyl-5-methyl phenol and 4-isopropyl phenol-3-methyl phenol; and the application can convert the mixed m-p-isopropyl phenol / m-p-propyl phenol with low value and small market demand into the marketable o-isopropyl phenol and p-isopropyl phenol and the like.

The invention relates to the technical field of bioengineering, in particular to a mask composition containing membrane of hen egg and thymol ferulate and application of the mask composition. Comprising the following components in parts by mass: 4 to 7 parts of glycerol, 0.05 to 0.15 part of an emulsifying agent, 2 to 3 parts of ethanol, 0.02 to 0.03 part of ethylparaben, 0.3 to 0.5 part of carbomer, 0.07 to 0.08 part of chorion ovi polypeptide and 0.03 to 0.05 part of thymol ferulate. The prepared gel mask is superior to commercially available products in the aspects of moisture retention and oxidation resistance, and the development of the mask can provide a new thought and practical basis for high-value utilization of natural active ingredients and development of multifunctional skin care products.

A composition comprising a solubiliser, at least one preservative, at least one liquid emollient and at least one antimicrobial agent, wherein the composition comprises thymol and carvacrol. The antimicrobial agent may comprise essential oils, active ingredients derived from essential oils or synthetic equivalents thereof and, optionally, additional antimicrobial compounds. The composition may comprise thymol, carvacrol, levulinic acid and lauric acid. The composition may be used for intra-anal douching and may be used to reduce the risk of the transmission of sexually transmitted diseases (STDs) and / or sexually transmitted infections (STIs). The composition may be essentially free of water and may be provided as a single unit dosage formulation. Alternatively, the composition may further comprise water and may be provided as a single unit dosage or multi-dosage formulation. Methods of making the composition that is essentially free of water and the composition further comprising water are also disclosed.

The application discloses an antifungal effect of an antifungal emulsion and application of the antifungal emulsion in prevention and treatment of chestnut corruption, and belongs to the technical field of food preservation. The application is used for preventing and treating corruption caused by fungal infection during the collection and storage period of chestnuts. The antifungal emulsion comprises an antifungal component, an emulsifier and distilled water. The antifungal component comprises at least one of plant essential oil and active components of plant essential oil. The plant essential oil is at least one of thyme essential oil, clove essential oil and perilla essential oil. The active components of plant essential oil are at least one of thymol, eugenol and perillaldehyde. The application has good prevention and treatment effect on fungal infection of chestnuts during the collection and storage period, and has the advantages of being green, safe and efficient.

The invention discloses a method for detecting alkylphenol by vortex-assisted liquid-liquid microextraction of supermolecular deep-eutectic solvent-based ferrofluid, which comprises the following steps: taking a novel supermolecular deep-eutectic solvent synthesized by thymol, octanoic acid and hydroxyethyl beta-cyclodextrin as raw materials as a carrier liquid, and taking oleic acid modified Fe3O4 nanoparticles as a carrier; and preparing the supramolecular eutectic solvent-based ferrofluid through an ultrasonic method. On the basis, the supermolecule eutectic solvent-based ferrofluid is used as an extraction agent for vortex-assisted liquid-liquid microextraction to extract alkylphenol in a sample to be detected, and then the alkylphenol is analyzed and detected by high performance liquid chromatography. The invention establishes a vortex-assisted liquid-liquid microextraction detection method for supermolecule deep-eutectic solvent-based ferrofluid, which can simply, quickly and sensitively detect alkylphenol in environmental water samples and beverages. The method has important application value and practical significance in the aspects of environment monitoring, food safety supervision and the like.