1088 results about "Methyl benzene" patented technology

The invention discloses a preparation method of a GLP-1R agonist Orforglipron, which comprises the following reaction steps: carrying out four-step reaction on an oxopiperidine compound (1) and (4-fluoro-3, 5-dimethylphenyl) hydrazine (2) to obtain a compound 8, and carrying out seven-step reaction on 5-bromo-indolecarboxylic acid (9) to obtain a compound 17. Then, the compound 8 and a compound 17 are subjected to an acid amine condensation reaction, and Orforglipron (LY3502970) is obtained. The preparation method is relatively low in cost, easy to operate, relatively short in synthetic route and suitable for industrial production and application, and the total yield can reach 32%.

The invention relates to a phosphorus-free zinc-free seawater special-purpose scale and corrosion inhibitor, which comprises, by weight, 20-25% of sulfonic acid modified polyaspartic acid, 8-12% of quaternized chitosan, 5-10% of a sulfonate copolymer, 5-10% of polyepoxysuccinic acid, 1-3% of benzotriazole or methyl benzotriazole, 0.5-1% of sodium tungstate, and the balance of deionized water. According to the formula, traditional corrosion inhibitors such as phosphorus and zinc are completely abandoned, functions are achieved through natural polymer derivatives such as sulfonic acid modified polyaspartic acid and quaternized chitosan, and the scale and corrosion inhibitor has the following environmental protection advantages that the scale and corrosion inhibitor does not contain phosphorus and zinc elements at all, and water eutrophication and heavy metal accumulation caused by a traditional phosphorus and zinc formula are avoided.

The invention discloses a quick-curing polyurethane seamless expansion joint material for roads and a preparation method, and belongs to the technical field of road engineering materials. The material is prepared from polyether polyol, polycaprolactone glycol, a bisphenol A epoxy-polyether block isocyanate terminated prepolymer, a methyl phenyl silicon-boron hybrid hydroxyl chain extender, diphenylmethane diisocyanate, calcium carbonate, wollastonite, a hindered amine anti-aging agent and dioctyl phthalate. Wherein the bisphenol A epoxy-polyether block isocyanate terminated prepolymer is prepared by the following steps: reacting bisphenol A with epoxy chloropropane to generate epoxy resin, reacting with polytetramethylene ether glycol, and introducing isophorone diisocyanate; the methyl phenyl silicon-boron hybrid hydroxyl chain extender is prepared by carrying out hydrosilylation and ethylene glycol reaction on methyl trimethoxy silane, 3-glycidyl ether oxypropyl trimethoxy silane and allylboronic acid pinacol ester; and the methyl phenyl silicon-boron hybrid hydroxyl chain extender is prepared by carrying out hydrosilylation on methyl trimethoxy silane, 3-glycidyl ether oxypropyl trimethoxy silane and allylboronic acid pinacol ester. The material has the advantages of quick curing property, weather resistance and high-temperature stability, and is suitable for road seamless expansion joint scenes.

The invention provides a preparation method of 4-fluoro-3, 5-dimethylphenylhydrazine hydrochloride, which comprises the following steps: salifying 4-fluoro-3, 5-dimethylaniline serving as a substrate with concentrated hydrochloric acid, reacting with sodium nitrite to prepare a diazo solution, reducing the diazo solution into corresponding phenylhydrazine by using alkaline sodium sulfite as a reducing agent system, and reacting the 4-fluoro-3, 5-dimethylphenylhydrazine hydrochloride with the diazo solution to prepare the 4-fluoro-3, 5-dimethylphenylhydrazine hydrochloride. And acidizing the 2, 5-dimethyl phenylhydrazine to obtain corresponding phenylhydrazine hydrochloride. According to the preparation method, sodium sulfite which is low in cost and easy to obtain is used as a reducing agent, the defects that metal residues are high, the environment is prone to being polluted and the raw material cost is high due to the fact that a metal reducing agent is adopted when phenylhydrazine hydrochloride is prepared in the prior art are overcome, the reaction is completed in a water phase, no organic solvent is adopted, and the concept of green chemistry is met; and the problems of complicated post-treatment and easy pollution caused by the adoption of an organic solvent can be effectively avoided.

The invention relates to the field of fire-resistant oil, in particular to phosphate-based fire-resistant oil with synergistically optimized flame resistance and stability and a preparation method of the phosphate-based fire-resistant oil. The fire-resistant oil comprises base oil and an additive, the base oil is a mixture obtained by esterification of mixed alkylphenol and phosphorus oxychloride; the molar percentage of the mixed alkylphenol is as follows: 4-6% of phenol; 11 to 14 percent of p-methylphenol; 22 to 26 percent of 2, 5-position dimethyl phenol; 0.8 to 1.5 percent of 2, 4-position dimethyl phenol; 2.5 to 4 percent of 2, 3-position dimethyl phenol; 0.4 to 0.6 percent of 4-ethyl phenol; 40 to 48 percent of 3, 5-position dimethyl phenol; 8 to 11% of 3-ethyl phenol; 3 to 5 percent of 3, 4-position dimethyl phenol; the additives comprise an antioxidant, a corrosion inhibitor, an anti-foaming agent and an anti-hydrolysis agent; the addition amount of the antioxidant is 0.05-5% of the total mass of the base oil; the addition amount of the corrosion inhibitor is 0.001%-0.08% of the total mass of the base oil; the addition amount of the anti-foaming agent is 0.001%-0.009% of the total mass of the base oil; the addition amount of the anti-hydrolysis agent is 0.001%-0.005% of the total mass of the base oil. The fire-resistant oil provided by the invention can be safely used under the working conditions of high temperature and extreme pressure.

The invention relates to the field of water treatment, and discloses a scale and corrosion inhibitor for seawater circulating cooling water, which is prepared from phosphonic acid grafted maleic anhydride-acrylic acid copolymer, hydroxyethylidene diphosphonic acid, amino trimethylene phosphonic acid, N, N-dimethylformamide, N, N-dimethylformamide, N, N-dimethylformamide, N, N-dimethylformamide, N, N- The anti-corrosion coating is prepared from the following raw materials: N, N-diethylaminomethyl-benzotriazole, gamma-aminopropyltriethoxysilane, zinc salt and a polyoxyethylene-polyoxypropylene block copolymer. The core of the invention is that all the raw material components form the thermo-sensitive polyelectrolyte compound through a self-assembly process. The compound is stably dispersed at low temperature by utilizing the cloud point effect of the block copolymer, and is subjected to phase change and preferential deposition on a high-temperature heat exchange surface, so that targeted and efficient delivery of various active components is realized. According to the invention, the problems of incompatibility of components and poor stability of a traditional compound agent are solved, the product has excellent storage stability, and efficient and synergistic corrosion and scaling control can be realized under high-temperature and high-salinity working conditions.

The invention discloses a continuous reaction device and method for producing 2-amino-4-methylbenzothiazole, and belongs to the technical field of compound production. The invention relates to a continuous reaction device for producing 2-amino-4-methylbenzothiazole, which comprises a first-stage reaction kettle and further comprises a stirring mechanism arranged in the first-stage reaction kettle and used for stirring chlorine and a mixed solution in the first-stage reaction kettle; the driving mechanism is arranged at the top of the first-stage reaction kettle and is used for driving the stirring mechanism to perform stirring action in the first-stage reaction kettle; the chlorine injection mechanism is connected with the stirring mechanism; the air exhaust mechanism is arranged at the top of the first-stage reaction kettle and is connected with the driving mechanism; the multistage reaction kettles are adopted for continuous operation to eliminate downtime, so that the problem of low production efficiency caused by repeated heating and cooling due to the use of intermittent reaction kettles in the traditional process is solved, the chlorine utilization rate is improved, and the production and processing cost is effectively reduced.

The invention relates to the field of sealing materials, in particular to a butyl rubber sealing material and a preparation method thereof. Comprising the following components in parts by weight: 50-70 parts of butyl rubber, 30-50 parts of a brominated isobutylene-p-methylstyrene copolymer, 30-50 parts of carbon black, 8-12 parts of an alkyl phenolic resin vulcanizing agent, 3-5 parts of zinc oxide, 1-3 parts of stearic acid, 1-3 parts of an anti-aging agent and 5-10 parts of a plasticizer. The butyl rubber provides ideal air tightness and heat aging resistance, bromine atoms are introduced into the brominated isobutylene-p-methylstyrene copolymer, co-vulcanization with the butyl rubber is achieved, it is ensured that a uniform and stable co-crosslinking network can be formed between the two rubber molecules, and the service life of the rubber is prolonged. The alkyl phenolic resin vulcanizing agent can form a C-C bond with high bond energy with two rubber molecules, so that the thermal aging resistance of the butyl rubber sealing material is effectively improved, the compression set is reduced, and the butyl rubber sealing material with excellent performance is prepared.

The invention discloses a preparation method of a spiro [4.5] trienone compound containing difluoro gamma-lactam, which comprises the following steps: reacting an N-(4-methoxyphenyl)-N-methyl-3-phenylpropanamide compound and an N-allyl-2, 2-difluoro-2-bromo-N-aryl acetamide compound in an argon atmosphere under the action of a photocatalyst and alkali to obtain the spiro [4.5] trienone compound containing difluoro gamma-lactam. And reacting under the irradiation of 467 nm blue light to obtain the spiro [4.5] trienone compound containing difluoro gamma-lactam. The reaction operation is simple and convenient, the product specificity is high, the substrate application range is wide, and the price is low. The invention provides a simple and efficient preparation method of the spiro [4.5] trienone compound containing difluoro gamma-lactam for the first time.

The invention discloses a continuous flow production method of high-purity chlorantraniliprole, and belongs to the technical field of chemical synthesis. The method comprises the following steps: simultaneously pumping a mixed solution containing 3-bromo-1-(3-chloro-2-pyridyl)-1H-pyrazole-5-formic acid, a solvent, an acid-binding agent and 2-amino-5-chloro-N, 3-dimethylbenzamide and a catalyst solution into a mixing unit of a continuous flow reactor I to form a reaction mixture flow; the material flow enters a continuous flow reactor I for condensation reaction to obtain a chlorantraniliprole solution; simultaneously pumping the mixed solution and a quenching agent solution into a continuous flow reactor II, and quenching to separate out crystals; and continuously centrifugally separating the quenching liquid containing the crystals, washing and drying to obtain a chlorantraniliprole refined product. According to the present invention, the full continuous flow process is adopted, the reaction unit and the post-treatment unit are included, the material continuously flows, and when the process is stable, the material composition, the temperature and other parameters in the reactor are only related to the reaction position and do not change with time, such that the production process and the product quality stability are ensured.

The invention relates to the technical field of chemistry, in particular to a synthesis process of 4-fluoro-3, 5-dimethylphenylhydrazine hydrochloride, which comprises the following steps: by taking 4-fluoro-3, 5-dimethylbromobenzene as a raw material and hydrazine hydrate as a hydrazine source, matching with alkali such as potassium hydroxide, sodium hydroxide or potassium phosphate and the like, reacting at the temperature of 60-80 DEG C to obtain the 4-fluoro-3, 5-dimethylphenylhydrazine hydrochloride. The preparation method comprises the following steps: by taking copper or nickel source catalysts such as cuprous bromide, cuprous iodide, nickel salicylate and the like, N, N-bis (2, 6-dimethylphenyl) oxamide as a ligand, hexadecyl trimethyl ammonium bromide as a stabilizer and a dioxane-water mixed system as a solvent, reacting at 80-110 DEG C under the protection of nitrogen, separating a reaction mixed solution after the reaction is finished, and separating the reaction liquid to obtain the target product. And purifying to obtain a finished product of the 4-fluoro-3, 5-dimethyl phenylhydrazine hydrochloride. Therefore, the problems that the synthesis of the 4-fluoro-3, 5-dimethylphenylhydrazine hydrochloride is poor in safety, low in production efficiency, poor in environmental friendliness, small in substrate application range and the like are solved.

The invention relates to the technical field of coatings, in particular to a solvent-free anti-doodling cover agent as well as a preparation method and application thereof. The solvent-free anti-doodling finishing agent is prepared from the following raw materials in percentage by mass: 80 to 95 weight percent of solvent-free methyl phenyl silicone resin, 1 to 5 weight percent of a curing agent, 3 to 8 weight percent of an adhesion enhancer, 0.5 to 3 weight percent of an anti-doodling auxiliary agent and 0 to 6 weight percent of an optional delustering agent. The core is that the adhesion enhancer is an enhanced silane coupling agent and is prepared by carrying out molecular-level chemical bonding on a titanium compound, the silane coupling agent and a self-made antifouling agent. The finishing agent disclosed by the invention has the advantages of high adhesive force, excellent stain resistance, adjustable glossiness and the like, and is suitable for base material protection of various scenes such as building outer walls, household crystal plating and artistic coatings.

The invention belongs to the technical field of organic matter synthesis, and particularly relates to a preparation method of 2-(2 '-hydroxy-3'-methallyl-5 '-methylphenyl) benzotriazole, in particular to a preparation method of cresol triazole trisiloxane. The invention relates to a preparation method of 2-(2 '-hydroxy-3'-methallyl-5 '-methylphenyl) benzotriazole, which comprises the following steps: mixing cresol trozole, methyl allyl chloride, Lewis acid and a first polar organic solvent, and carrying out Friedel-Crafts alkylation reaction to obtain the 2-(2'-hydroxy-3 '-methallyl-5'-methylphenyl) benzotriazole. When the 2-(2 '-hydroxy-3'-methallyl-5 '-methylphenyl) benzotriazole is prepared, the conventional Claisen rearrangement reaction is replaced, and the 2-(2'-hydroxy-3 '-methallyl-5'-methylphenyl) benzotriazole is prepared by adopting the Friedel-Crafts alkylation reaction of cresol trozole, so that the safety risk of process operation is reduced.

The invention provides a preparation method of a (S)-5-(2, 2-dimethyl tetrahydro-2H-pyran-4-yl)-N-methyl-N-phenyl-1H-indole-2-formamide compound, which comprises the following steps: by taking a compound 1 as an initial raw material, reacting the compound 1 with a boric acid ester reagent to obtain a boric acid ester compound 2; the method comprises the following steps: by taking a compound 3 as an initial raw material, reducing carbonyl through enzyme catalysis to obtain a compound 4, then protecting alcoholic hydroxyl through a sulfonylation reagent to obtain a compound 5, and finally, directly coupling the compound 5 with a compound 2 under the action of a catalyst to obtain a target product compound 6. The whole process is low in experimental condition requirement, simple to operate, high in yield and suitable for process amplification.

The invention discloses a preparation method of 2-chloro-4-(4-fluoro-2-methylphenyl)-5-aminopyridine as an elinnetin intermediate, and belongs to the technical field of medicine synthesis. According to the invention, cheap and easily available 3-nitro-4-hydroxypyridine is used as an initial raw material, and the 2-chloro-4-(4-fluoro-2-methylphenyl)-5-aminopyridine is synthesized at low cost and high yield through the steps of halogenation, coupling, hydroxylation, reduction, condensation and the like. The raw materials used in the whole process are simple and easy to obtain, the reaction conditions are milder, and the reaction route is short. According to the invention, the Suzuki coupling reaction is firstly carried out, and then the hydroxylation of the pyridine 2 position is carried out, so that the use of an anhydrous reagent and harsh anhydrous reaction conditions are effectively avoided, and the reaction cost is remarkably reduced. In addition, the method is easy and convenient to operate, good in stability, high in total yield and suitable for industrial large-scale production.

The invention belongs to the field of rubber additives, and particularly relates to an anti-aging agent as well as a synthesis method and application thereof. RT base and a phenol compound are used as raw materials for synthesis under the action of a catalyst; the phenol compound is a mixture of phenol and o-methylphenol. According to the invention, RT base (p-aminodiphenylamine) is used as a precursor and reacts with phenol or o-methylphenol in the presence of a catalyst to produce the anti-aging agent. Salt-containing waste water is not generated in the precursor production process, and compared with hydroquinone serving as a precursor, the precursor has the obvious cost advantage and the environment-friendly advantage.

The present application relates to a kind of foam type organic chlorine disinfectant and its preparation method and application, belong to disinfectant technical field.Utilize the modification treatment of magnesium sulfate with polysilicic acid, make and form stable package system between modified magnesium sulfate and organic chlorine, greatly improve the stability and long-acting of effective chlorine component in the process of use;While introducing the synergism between surfactant and sodium dimethyl benzene sulfonate, an additional protective layer is constructed, further strengthens the overall stability of organic chlorine disinfectant, blocks the harmful contact that organic chlorine disinfectant can encounter under complex or adverse environmental conditions, effectively prevents the performance decline or potential harm caused by environmental factors, ensures the safe and efficient use of disinfectant.The foam type organic chlorine disinfectant of the present application utilizes double package system, not only improves the long-acting and stability of disinfection effect, but also significantly enhances the environmental adaptability and use safety of product.

The invention provides a preparation method of hexafluoroisobutene, which comprises the following steps: firstly, reacting hexafluoroisopropanol with p-toluenesulfonyl chloride to generate an organic phase, then reacting with a cyano source to obtain 3, 3, 3-trifluoro-2-(trifluoromethyl) propionitrile, then reacting with an acid solution and a reducing agent in sequence to obtain hexafluoroisobutanol, and finally reacting with an acid solution and a reducing agent to obtain the hexafluoroisobutanol. And finally, carrying out alkali dehydration to generate hexafluoroisobutene. The preparation method provided by the invention is simple in process route and mild in reaction condition, the solvent used in the preparation process can be recycled, the pollution in the preparation process is reduced, and the preparation method is less in three wastes, environment-friendly and suitable for large-scale production.

The invention provides a method for preparing p-chloromethyl styrene, which comprises the following steps: (1) in the presence of a catalyst and an assistant, carrying out reaction on paraformaldehyde and hydrogen chloride to obtain a chloromethylation reagent; (2) reacting beta-halogenated ethyl benzene with the chloromethylation reagent obtained in the step (1) to obtain chloromethyl halogenated ethyl benzene; (3) adding an extracting agent into the chloromethyl halogenated ethylbenzene reaction liquid obtained in the step (2) for extraction to obtain an oil layer containing chloromethyl halogenated ethylbenzene and a water-containing acid layer, and crystallizing the oil layer to obtain purified p-chloromethyl halogenated ethylbenzene; and (4) in the presence of a solvent, carrying out elimination reaction on the purified p-chloromethyl halogenated ethyl benzene and alkali to obtain p-chloromethyl styrene.

The invention provides a polymer cationic asphalt emulsifier as well as a preparation method and application thereof. According to the preparation method of the polymer cationic asphalt emulsifier, three monomers including 9-octadecenoic acid methyl ester, maleic anhydride and p-vinyltoluene are utilized to react to obtain the polymer cationic asphalt emulsifier. Based on a free radical polymerization technology, various functional groups (long-chain alkyl, a methyl styrene chain, imidazoline and the like) are integrated into a single polymer skeleton, so that the interfacial activity of an emulsifier is expected to be improved, the stability and the use performance of emulsified asphalt are improved, high efficiency and economical efficiency are achieved, and the development trend of green road materials is met. Compared with a traditional asphalt emulsifier, the polymer cationic asphalt emulsifier has higher surface activity and excellent high and low temperature stability.

The invention provides a chemical or enzymic method regenerated PET and PTA screening method, which comprises the following steps: pretreating a PET or PTA sample 1, and measuring the content of p-toluic acid, the content of p-carboxybenzaldehyde and the content of m-terephthalic acid by using high performance liquid chromatography; the method comprises the following steps: pretreating a PET or PTA sample 2, pretreating by using a high-temperature pyrolysis method, and measuring an isotope ratio of oxygen-18 to oxygen-16 by using an isotope ratio mass spectrometer; the method comprises the following steps: calculating a cleanliness index, an oxy-18 index and a bottle flake index by using a formula based on a test result, and classifying PET and PTA samples through a decision tree according to the indexes; combining and mixing the PET and PTA products based on the classification result and the requirements of downstream customers on the regeneration method and the regenerated material content; the method is convenient, accurate and reliable, the classification result is objective, the screening efficiency of PET and PTA regenerated by a chemical or enzyme method can be improved, and the economic cost is saved.

The present invention relates to the preparation of cyantraniliprole, comprising the preparation of 8-methyl-2,4-dioxo-1,4-dihydro-2H-benzo[d][1,3]oxazine-6-carbonitrile key intermediate via 2-amino-5-((hydroxyimino)methyl)-3-methylbenzoic acid. Wherein hydroxylamine attacks a benzylic formyl group, to obtain the 2-amino-5-((hydroxyimino)methyl)-3-methylbenzoic acid, that undergoes simultaneously or by consecutive steps dehydrogenation and cyclization to obtain the benzo[d][1,3]oxazine group and the cyano group of the desired product. In addition, an improved method for the synthesis of the benzylic formyl group is also displayed.

The invention relates to the technical field of coatings, discloses a multifunctional fireproof and waterproof polysiloxane coating and a preparation method thereof, and aims at solving the problems that the hydrophobic function of an existing fireproof and waterproof polysiloxane coating is irreversibly lost after a fire disaster, and the fireproof and waterproof synergistic performance is remarkably attenuated in a medium-high-temperature environment. Hydroxyl-terminated methyl phenyl siloxane is used as matrix resin, and is matched with a flame-retardant system composed of melamine modified ammonium polyphosphate, pentaerythritol and amino modified nano-montmorillonite, a hydrophobic repair system composed of polysiloxane capsule wall fluorosilane microcapsules, an interface modifier compounded by an epoxy group and an amino silane coupling agent, and a special auxiliary agent. A three-dimensional covalent network is constructed to anchor all the components, efficient charring and temperature response type hydrophobic repair are achieved, the finished product is prepared through microcapsule preparation, modified flame retardant compounding and coating main body blending, and the finished product has excellent fireproof and waterproof performance, a renewable hydrophobic function after a fire disaster and stable performance at medium and high temperatures and is suitable for industrial long-term protection scenes.

The invention provides a bio-based crude terephthalic acid hydrofining method, and belongs to the technical field of terephthalic acid hydrofining. The method comprises the following steps: carrying out recrystallization pretreatment on bio-based crude terephthalic acid, mixing the pretreated bio-based crude terephthalic acid with a solvent, adding a catalyst, carrying out a hydrofining reaction, replacing the solvent after the reaction is finished, carrying out recrystallization treatment on a hydrofined product, washing with water, and drying to obtain refined terephthalic acid, the method disclosed by the invention has the advantages of high impurity removal rate, mild reaction conditions and small process pollution, the refining of the bio-based crude terephthalic acid is realized, the obtained terephthalic acid can meet the requirements of an existing industrial method, and the concentration of impurities p-carboxybenzaldehyde is less than or equal to 25ppm and the concentration of methyl benzoic acid is less than or equal to 180ppm.

Provided herein are solid forms and methods of prepapation relating to (R) -3- (tert-butyl) -N-(1- (4- (6- (6- (4- ( (1- (4- (2, 4-dioxotetrahydropyrimidin-1 (2H) -yl) phenyl) piperidin-4-yl) methyl) piperazin-1-yl) pyridin-3-yl) -7H-pyrrolo [2, 3-d] pyrimidin-4-yl) -2-methylphenyl) ethyl) -1,2,4-oxadiazole-5-carboxamide.

The invention relates to a high-efficiency low-toxicity fireproof heat-insulation composite coating and a preparation method thereof, and the preparation raw materials of the high-efficiency low-toxicity fireproof heat-insulation composite coating comprise the following components in parts by weight: 20-30 parts of modified polysiloxane, 15-25 parts of ammonium polyphosphate, 8-15 parts of melamine, 15-28 parts of an inorganic filler, 10-15 parts of water, 5-10 parts of a cosolvent, and 1-3 parts of a functional auxiliary agent. The modified polysiloxane is an A-B-C type three-section type block copolymer, wherein the A section is a polydimethylsiloxane or methyl phenyl siloxane block; the segment B is an organic silicon chain segment containing a phosphazene structural unit; and the segment C is a polyethylene glycol or polyoxyethylene block. According to the invention, the modified polysiloxane is cooperated with the ammonium polyphosphate salt and the melamine, so that the composite coating has the effects of high-efficiency fire prevention and heat insulation, low toxicity, environment friendliness and excellent film forming performance.

The invention belongs to the technical field of chiral material preparation, and particularly relates to a one-dimensional bismuth-based chiral perovskite crystal and a preparation method and application thereof. The general formula of the chiral perovskite crystal is (R-beta-MPA) 2BiI5 or (S-beta-MPA) 2BiI5, the chemical formula of the chiral perovskite crystal is C18H28BiI5N2, the R-beta-MPA represents (R)-(+)-beta-methyl phenylethylamine, the S-beta-MPA represents (S)-(-)-beta-methyl phenylethylamine, the R-beta-MPA represents (R)-(+)-beta-methyl phenylethylamine, and the S-beta-MPA represents (S)-(-)-beta-methyl phenylethylamine. The crystallographic data of the (R-beta-MPA) 2BiI5 include that the crystal belongs to an orthorhombic crystal system and a P212121 space group, and the cell parameters are as follows: alpha is equal to 90 degrees, beta is equal to 90 degrees, and gamma is equal to 90 degrees; the crystallographic data of the (S-beta-MPA) 2BiI5 comprises that the crystal belongs to an orthorhombic crystal system and a P212121 space group, and the cell parameters are as follows: alpha is equal to 90 degrees, beta is equal to 90 degrees, and gamma is equal to 90 degrees.

The present disclosure relates to crystal forms of a triazine dione derivative and a preparation method therefor. Specifically, the present disclosure relates to different crystal forms of (S)-6-((1-(2-fluoro-5-methylphenyl)ethyl)amino)-3-(tetrahydro-2H-pyran-4-yl)-1,3,5-triazine-2,4(1H,3H)-dione and a preparation method therefor. The crystal forms of (S)-6-((1-(2-fluoro-5-methylphenyl)ethyl)amino)-3-(tetrahydro-2H-pyran-4-yl)-1,3,5-triazine-2,4(1H,3H)-dione provided by the present disclosure have good stability and can be better used for clinical treatment.

The invention relates to the technical field of catalytic synthesis, in particular to a chloromethylation catalyst, a preparation method of the chloromethylation catalyst and a method for preparing high-purity ortho-position, meta-position and para-position chloromethyl styrene through the chloromethylation catalyst, and the chloromethylation catalyst is prepared by loading sulfonic acid compounds and (or) pyridine compounds and (or) copper salt on a molecular sieve. The method can improve the localization selectivity of chloromethylation. The method for preparing high-purity ortho-position, meta-position and para-position chloromethyl styrene comprises the following steps of: reacting beta-bromophenylethane, paraformaldehyde and lewis acid in the presence of the chloromethylation catalyst to generate chloromethyl beta-bromophenylethane, and then performing elimination reaction under an alkaline condition to generate a chloromethyl styrene crude product; the high-purity ortho-position, meta-position and para-position chloromethyl styrene is obtained after the crude product is rectified, the brand-new catalyst is adopted in the method, the reaction selectivity is enhanced, the process is simple, and industrial production is facilitated.

The invention relates to the technical field of tire rubber manufacturing, and discloses a low-odor low-VOC sidewall rubber composition, a mixing method thereof and a tire, a brominated copolymer (BIMS) of isobutene and p-methylstyrene is adopted, and the use of an amine anti-aging agent is canceled; according to the invention, tetrabenzylthiuram disulfide (TBzTD) is adopted as a main accelerant, and a traditional sulfenamide accelerant is replaced; the softening and reinforcing resin is adopted to replace an oil softener, so that small molecular substances in aromatic hydrocarbon oil or naphthenic oil are prevented from being separated out, and phenol possibly generated by using phenolic resin is avoided; carbon black is matched with a small amount of white carbon black, so that odor molecules are effectively adsorbed; and the steps of lifting an upper top peg and opening a charging door for exhausting are added in the plastifying and mixing sections. The synergistic effect of the optimized formula raw materials effectively avoids the generation of odor molecules, the escape of a large number of VOC molecules is improved, and the exhaust step further reduces the residual quantity of the VOC molecules in the final mixed rubber, so that the odor grade of the tire is improved.