515 results about "Benzyl alcohol" patented technology

Transdermal delivery compositions and topical compositions for application to the skin are provided. The transdermal delivery composition includes at least two penetrants working synergistically but by disparate biochemical pathways. In one embodiment, the transdermal delivery system includes benzyl alcohol and lecithin organogel. The transdermal delivery compositions are used in a variety of topical compositions as a means of transdermally delivering and topically administering different drugs and agents, including compositions promoting collagen biosynthesis, retinoids and skin lighteners, chemical denervation agents such as BOTOX®, anti-fungal agents, anesthetics and non-steroidal anti-inflammatory drugs (NSAIDs). In addition, these topical compositions may be used in combination with non-ablative treatment modalities, such as microdermabrasion, laser-based skin remodeling and radio-frequency-based skin remodeling.

The invention is a composition comprising applying to a substrate a stream of an adhesive comprising: one or more epoxy resins; one or more rubber modified epoxy resins; one or more toughening compositions comprising the reaction product of one or more isocyanate terminated prepolymers and one or more capping compounds having one or more phenolic, benzyl alcohol, aminophenyl, or, benzylamino groups wherein the reaction product is terminated with the capping compounds; one or more curing agents for epoxy resins and one or more catalysts which initiate cure at a temperature of about 100° C. or greater; and optionally; fillers adhesion promoters, wetting agents or rheological additives useful in epoxy adhesive compositions; wherein the adhesive composition has a viscosity at 45° C. of about 20 Pa.s to about 400 Pa.s. The composition can be used as an adhesive and applied as a stream using a high speed streaming process.

The invention discloses a Huangguanyin black tea processing technology. The Huangguanyin black tea processing technology utilizes Huangguanyin which is a Tieguanyin-Huangjingui hybrid as a raw material. The Huangguanyin black tea has effects of generating body fluid and clearing heat, inducing dieresis, diminishing inflammation and killing bacteria, removing toxins, and nourishing stomach. The Huangguanyin black tea processing technology improves the existing processing technology, reduces volatilization of aromatic alcohol, geraniol, benzyl alcohol, alpha-phenethyl alcohol, cis-3-vinyl ester and methyl salicylate, and reduces harmful substances such as trans-2-hexenal. Through the Huangguanyin black tea processing technology, the Huangguanyin black tea has a good fragrance, a mellow taste and a golden color.

The present invention provides a non-water soluble, film-forming composition which adheres to body tissue and forms a pharmaceutical carrier to provide localized delivery of an antifungal agent to a treatment site. The composition will typically include: (a) an alkyl cellulose; (b) a hydroxyalkyl cellulose; (c) a pharmaceutically acceptable polar protic solvent; (d) an antifungal agent selected from the group of naftifine, ciclopirox, terbinafine, pharmaceutically acceptable salts thereof, and combinations thereof; (e) an glycol ether; (f) an antipruritic agent selected from the group of camphor, menthol, butamben picrate, metacresol, benzyl alcohol, camphorated metacresol, juniper tar, phenol, phenolate sodium, resorcinol, camphorated metacresol, carbolic acid, and combinations,; and (g) a solubility enhancing agent, a surfactant, a wetting agent, or a combination thereof. The present invention also provides for the use of the composition composition of the present invention, in treating a fungal infection (e.g., nail fungus) in a mammal afflicted with such an infection.

A non-addictive analgesic sustained-release drug delivery system, comprising: (1) a narcotic analgesic drug having a concentration of 1 mg / ml-160 mg / ml, the drug being selected from a group consisting of: a local analgesic drug, and the combination of the local analgesic drug and a nonsteroidal analgesic drug and / or an opioid analgesic drug; (2) a drug menstruum in a proportion of 1%-75% (v / v), the menstruum being selected from a group consisting of benzyl alcohol, ethanol, benzyl benzoate, ethyl lactate, and tetrahydrofurfuryl polyethylene glycol ether; and (3) a drug sustained-release formulation having a proportion of 25%-99% (v / v), the sustained-release formulation being selected from a group consisting of natural vegetable oil, synthetic lipid, artificially improved half-natural lipid and derivative thereof. Also disclosed are a preparation process and use of the sustained-release drug delivery system.

The invention discloses concrete flavouring for tobacco and a preparation method and application thereof, belonging to the technical field of additive for tobacco. In the invention, waste tobacco used as raw material is sequentially fermented with rhodococcus, bacillus pumilus and bacillus subtilis to reduce nicotine in the waste tobacco and convert ferulic acid in the tobacco into incense ingredients such as 4-guaethol and vanillin; after fermentation is finished, the conventional biochemical technology is utilized to extract the incense ingredients from the waste tobacco for preparing concrete flavouring. The concrete flavouring obtained by invention contains the following main incense ingredients with higher contents: benzyl alcohol, solanone, vanillin, BETA-damascenone, dihydroactinidiolide, megastigmatrienone, duvatriene diglycol and neophytadiene. Results of an aromatic flavouring smoke panel test show that the concrete flavouring has obvious effects of increasing tobacco aroma,smoothing alcohol and smoke, reducing irritation, covering impurity gas and improving smoking taste of cigarettes.

The invention discloses a tobacco extract, an extracting method and application and belongs to the field of tobacco additives. The tobacco extract is extracted with the method including the following steps that firstly, propylene glycol is added into tobacco raw materials, and then baking is carried out after standing; secondly, smashing is carried out, and a solvent is added into powder materials for extraction; thirdly, extract liquid passes through an ultrafiltrtion membrane, penetrating liquid is obtained and subjected to reduced pressure distillation, and concentrate is obtained; fourthly, the concentrate is subjected to secondary separation with a molecule distillation method, light components are collected, and the tobacco extract is obtained. The extract contains rich megastigmatrienone, Damascone, neophytadiene, phenylcarbinol, phenethyl alcohol, farnesylacetone and pyrone and furanone aroma components, and the tobacco extract is thick in baking aroma and tobacco aroma, good in penetration, small in irritation and miscellaneous gas, high in satisfaction, capable of improving the smoking quality of cigarettes and providing a certain amount of nicotine to meet the physiological needs of consumers when used.

The invention discloses a technique for using methylbenzene to prepare benzaldehyde and benzene methanol by air oxidation and equipment. In a reaction separating system consisting of a multistage oxidation reactor as well as a gas-liquid separator, a lateral line fractionating column or a fractionating column system, 0.1 to 50ppm of monometallic porphyrin or u-oxygen bimetallic porphyrin is separately used as a catalyst, or metallic porphyrin and phthalimide (or salt) are used as a mixed catalyst according to the weight ratio of 1:20 to 100; when the reaction temperature is 80 to 200 DEG C, the methylbenzene is maintained in a multistage oxidizer for 60 to 180 minutes and prepared into the benzaldehyde and benzene methanol by catalytic oxidation; and the gas-liquid separation and purification are carried out. Compared with the prior art, the technique and equipment can obviously improve the conversion rate of the methylbenzene, and the conversion rate of the methylbenzene can reach to be more than 95% by experiments; in addition, the technique and equipment also can improve the selection of the benzaldehyde and benzene methanol, and the selection of the benzaldehyde and benzene methanol can reach to be more than 50%.

The invention discloses a method for preparing a tungsten disulfide nano sheet. The method is achieved by the following technological processes: adding a certain amount of Li2CO3 powder, directly commercially purchased WS2 powder and 40mL of organic solvent phenylcarbinol solution to a high-pressure reaction kettle of which the volume is 50mL; keeping the high-pressure reaction kettle at 200 DEG C for 24-72 hours; carrying out solvothermal reaction; drying in vacuum and collecting a reaction product; adding to a mixed solution of deionized water and NN-dimethylformamide with volume ratio is 1:1; continuously and ultrasonically vibrating for 12-24 hours; and drying in vacuum and collecting the final product to obtain finally layered tungsten disulfide nano sheet. The product has the characteristics of being good in crystallinity, good in dispersibility, small in environmental pollution, simple in experiment method, and easy to operate and popularize.

Long term storage stable fulvestrant-containing compositions are disclosed. The compositions can include fulvestrant; a solvent selected from dimethyl sulfoxide (DMSO), glycofurol, N-methyl pyrrolidone, and mixtures thereof; an oil mixture selected from a mixture of caprylic and capric triglycerides, a mixture of caprylic, capric and linoleic triglycerides, a mixture of caprylic, capric and succinic triglycerides, and a mixture of propylene glycol dicaprylate and propylene glycol dicaprate; and a sustained release member selected from benzyl benzoate, dihydrolipoic acid, benzyl alcohol and lipoic acid. The fulvestrant-containing compositions have less than about 5% total impurities, on a normalized peak area response (“PAR”) basis as determined by high performance liquid chromatography (“HPLC”) at a wavelength of 223 nm, after at least about 24 months of storage at a temperature of from about 5° C. to about 25° C.

The invention belongs to the technical field of daily cosmetics and relates to a pearl amino acid stayup brightening and moistening mask and a preparation method thereof. The pearl amino acid stayup brightening and moistening mask is prepared from hydrolyzed pearl powder, PEG / PPG-17 / 6 copolymer, hydroxyethyl urea, nicotinamide, PEG-50 shea butter, witchhazel extract, Aloe vera extract, lactobacillus / soybean fermented product extract, lalang grass rhizome extract, viscum album leaf extract, xylitol-based glucoside, alcohols, esters, acrylic acid (ester) / C10-30 alkanol acrylic ester cross-linked polymer, triethanolamine and phenylcarbinol. Pearl essence is fused with an amino acid compound, in coordination with plant active factors, fatigue and darkness of skin generated after stayup can be relieved and repaired, moisturizing, hydrating, lubricating and brightening are synchronously conducted, and fresh, tender and exuberant bright skin is represented. The pearl amino acid stayup brightening and moistening mask has the advantages of being simple in process, comprehensive in nutrition, obvious in effect and the like, and is a good brightening and skin-beautifying skin care product.

The invention discloses a synthesis method for increasing the Pd content of a metal organic framework based on Zr(IV) ions. The method comprises the following steps: performing a coordination polymerization reaction between an organic ligand (I) and ZrCl4, and performing post-synthesis modification of the product, wherein the post-synthesis modification comprises the following specific steps: enabling a coordination polymerization reaction product, 2-pyridylaldehyde or salicylaldehyde and a catalyst formic acid in a molar ratio of 1:(1-4):(0.1-0.3) to react in an organic solvent; performing centrifugal washing of the product and dispersing in an organic solvent; adding palladium nitrate in a molar ratio of 1:(0.8-1.2); after the reactions, centrifuging and drying to obtain powder; dispersing the obtained powder into water; adding sodium borohydride in a molar ratio of 1:(0.5-1.5); and after the reactions, centrifuging, washing and drying to obtain the product. In the invention, the synthesized compound is an organic-inorganic composite supermolecular material and has a metal organic framework which is easy to operate and low in cost and has nanoscale particle size; and the compound has very high efficiency when being used as a catalytic material for benzyl alcohol oxidation and benzaldehyde condensation.

The invention relates to a terminated unsaturated polyester resin which is a polycondensate of dihydric alcohol and a dibasic acid or estolide. The dibasic acid or estolide comprises a saturated dibasic acid or estolide and an unsaturated dibasic acid or estolide; a reaction system of the dihydric alcohol and the dibasic acid or the estolide is terminated by monohydric alcohol; the terminated unsaturated polyester resin has molecular weight of 800-1500 and comprises the following components by mass percent; 22-30 percent of dihydric alcohol, 24-30 percent of saturated dibasic acid, 15-19 percent of unsaturated dibasic acid, 3-6 percent of monohydric alcohol and 22-29 percent of cross linker, wherein the monohydric alcohol is one of isooctanol, cyclohexanol and phenylcarbinol. The invention has the advantages as follows: a termination method is used for preparing the unsaturated polyester resin, thus being capable of improving the hydrolysis resisting stability and the scale-resisting performance and reducing the volatilization and shrinkage of resin; and when the resin prepared by the method is taken as matrix resin to produce boards such as rostone, deck plate, quartz and the like, the yield of products can be improved, the cracking phenomenon can be reduced, and the products can be used in occasions with higher water-proof requirement.

The invention discloses a method for preparing a 2-substituted benzoxazole compound. According to the method, a benzylamine compound or a benzaldehyde compound or a benzyl alcohol compound, and o-toluidine-N-methyl-o-phenylenediamine, ortho-aminophenol and o-aminobenzenethiol serve as raw materials, metals palladium, platinum or ruthenium serves as a catalyst, and N,N-dimethylformamide, N,N-dimethylacetamide or N-methylpyrrolidone serves as a solvent. The method comprises the following preparation steps: (1) mixing the raw materials; (2) reacting; (3) separating and extracting; and (4) drying and concentrating. An oxidant and a hydrogen acceptor are not required in the whole preparation process, and the used partial catalysts can be recycled. The method is high in atom economy, simple in aftertreatment and mild in reaction conditions and has a certain industrial application prospect.

The invention relates to a liquid wound dressing and its preparation method, belonging to the field of medical supplies. The wound dressing comprises the following raw materials by weight: 0-15% of camphor, 0-23% of benzyl alcohol, 0-30% of isopropyl myristate, 0-5% of a bactericide, 1-20 % of a film forming agent, 0-20% of a plasticizer and 0-5% of a surfactant, with the balance being a solvent. The liquid dressing prepared in the invention has the advantages is simple and convenient to apply, can rapidly form a film when applied on the affected skin part of a patient and has good toughness and elasticity; the liquid dressing is soft and comfortable and can protect a wound, prevent infection and promote wound healing; and the liquid dressing is simple and convenient to use, not restricted by the shape and location of wounds, waterproof and air-permeable and allows a wound to be visible. In addition, the preparation method is simple in process, low in cost and easy for industrial production. The wound dressing in the invention is applicable to treatment and nursing of cuts, abrasions, lacerations, and other damaged areas of skin.

The invention relates to a multilevel porous molecular sieve catalyst as well as a preparation method and application thereof. The preparation method of the multilevel porous molecular sieve catalyst comprises the following steps: adding an organic template agent ethanol solution into an aluminum source, a silicon source and a silane ethanol solution to form gel, performing air drying on the gel to obtain dry gel, adding water and tetrapropylammonium hydroxide into the dry gel to obtain a mixture, putting the mixture into a high-pressure kettle, crystallizing the mixture for 3 days at the temperature of 180 DEG C to obtain a multilevel porous ZSM-5 molecular sieve, uniformly mixing the multilevel porous ZSM-5 molecular sieve with gamma-Al2O3, adding a dilute nitric acid solution, then performing mixed kneading, performing strip extruding for forming, drying and roasting in air so as to obtain a carrier; and soaking the carrier by utilizing a magnesium acetate solution, drying and roasting the carrier to obtain a phenylcarbinol alkylation catalyst. When the prepared catalyst is applied to the phenylcarbinol alkylation reaction, the catalyst has the advantages that coke and carbon are not easily generated, the activity is high, and the product selectivity is high. Compared with other catalysts in the prior art, for the catalyst disclosed by the invention, the activity and the reaction stability are high, and the service life is longer.

The invention belongs to the technical field of carbon material manufacturing techniques, and relates to a preparation method of graphene. The preparation method comprises the following steps: mixing pyridine and alcohol organic solvent in a ratio of 1:10-1:1 at room temperature, wherein the alcohol organic solvent can be any one or combination of methanol, ethanol, benzyl alcohol and the like; carrying out ultrasonic dispersion on graphite oxide in the mixed solution, wherein the concentration of the graphite oxide in the mixed solution is 1-8 mg / mL; transferring the dispersed solution into a high-pressure reaction kettle; and heating to 120-200 DEG C to react for 12-48 hours, thereby obtaining the graphene. The graphene prepared by the method provided by the invention has the advantages of high degree of reduction and large specific area, and avoids using any high-toxicity reducer. The graphene prepared by the method provided by the invention can be widely used in the fields of supercapacitors, capacitor type desalting and the like.

The invention relates to the technical field of selective photocatalytic oxidation synthesis, which more particularly relates to a semiconductor TiO2 photocatalyst modified with promoter on the surface and the corresponding preparation method, as well as the catalyst application on the selective oxidation of primary alcohol or secondary alcohol to Aldehyde or Ketone. The invention is designed to perform chemical treatment on the TiO2 surface to convert the TiO2 into organic nitro-oxy radical which can highly selectively react with the primary or secondary alcohol to obtain the corresponding aldehyde or ketone as for the selectivity of stereo-hindrance, through an in-situ conversion of photo-excited holes. The selective conversion rate to any hydrin by the catalyst in the invention can achieve up to 99%, while commonly the conversion rate is over 90%, particular to the aromatic alcohol e.g. benzyl alcohol of over 99% of selectivity; both the catalyst and promoter can be reused for times through simple filtration, have long life without carbon deposition; the conditions of both preparation and reaction are mild.

Disclosed is a topical skin cleanser comprising Silybum marianum fruit extract, Momordica grosvenorii fruit extract, and a cosmetic vehicle comprising at least 50% by weight of the composition of water and disodium EDTA, glycerin, phenoxyethanol, triethanolamine, 3-Iodo-2-propynyl butyl carbamate, and benzyl alcohol.

An improved composition for treatment of the skin comprises: (1) methionine and cysteine in a quantity sufficient to accelerate restoration of the integrity and fullness of the skin; (2) a mixture of essential amino acids in a quantity sufficient to accelerate restoration of the integrity and fullness of the skin, the mixture comprising isoleucine, leucine, lysine, phenylalanine, threonine, tryptophan, valine, histidine, and arginine; (3) at least one antioxidant in a quantity sufficient to accelerate restoration of the integrity and fullness of the skin; (4) at least one cross-linking agent in a quantity sufficient to accelerate restoration of the integrity and fullness of the skin; (5) at least one metallic catalyst in a quantity sufficient to accelerate restoration of the integrity and fullness of the skin; (6) at least one transepidermal delivery agent in a quantity sufficient to promote delivery of the composition to the skin; and (7) a topical pharmaceutically acceptable carrier. The antioxidant can be ascorbic acid. The cross-linking agent can be proanthocyanidin or silybin. The metallic catalyst can be Cu (II) in a suitable cupric salt. The transepidermal delivery agent can be benzyl alcohol.

The invention discloses glycosyl transferase for catalyzing synthesis of gastrodin or salidroside, a gene coding the glycosyl transferase and application of glycosyl transferase. The glycosyl transferase for catalyzing synthesis of gastrodin or salidroside is as shown in SEQ ID No.1. Experiments prove that the glycosyl transferase for catalyzing synthesis of gastrodin or salidroside can be used for respectively catalytically converting hydroxy-benzyl alcohol into gastrodin and converting tyrosol into salidroside, and the yield of gastrodin and salidroside can be remarkably improved.

The invention discloses a method for preparing benzaldehyde by catalytically oxidizing phenylcarbinol through Pt / BiOCl-metal oxide serving as a catalyst. The method comprises the following steps: by taking a noble metal Pt / BiOCl-metal oxide compound system as the catalyst, dispersing phenylcarbinol and the catalyst into water, and continuously stirring under a relatively low-temperature dark condition for 3 to 10 hours, wherein the generation selectivity of the benzaldehyde can be 99 percent or above, and the yield of the benzaldehyde is retained within a range of 80 to 100 percent according to different types of carriers. The method has the following active effects that 1, the reaction can be carried out at relatively low temperature, such as room temperature of 25 DEG C; 2, low-cost air is used as an oxidant, so that the problem of environmental pollution caused by the fact that a high-cost metal such as chromium and manganese is used as the oxidant is solved; 3, no alkaline substances serving as an auxiliary catalyst are added into a reaction system; 4, basically no side effect is caused in a reaction process, and the generation selectivity of the benzaldehyde is retained at 99 percent or above; 5, equipment devices for reaction and an operation process are simple.

The invention discloses a supported vanadyl pyrophosphate catalyst prepared by selective oxidation of n-butane and a preparation method thereof, and relates to a maleic anhydride catalyst prepared by selective oxidation of n-butane. The catalyst contains an active ingredient and a carrier, wherein the active ingredient is (VO)2P2O7, and the carrier is TiO2 treated by a phosphoric acid solution. The preparation method comprises the steps of soaking the TiO2 into the phosphoric acid solution, stirring in an oil bath pan, filtering, washing and drying to obtain the carrier TiO2; mixing V2O5 with an isobutanol-phenylcarbinol mixed solvent, heating for refluxing to ensure that the mixed solution becomes black, then adding the carrier TiO2, refluxing continuously, cooling the mixed solution, then adding phosphoric acid, heating, refluxing continuously to generate a blue sediment, cooling, filtering, washing the obtained solid, drying the filtrate, carrying out tabletting, smashing, and screening to obtain a catalyst precursor; and putting the prepared catalyst precursor into a fixed bed roasting furnace of a mobile system, and roasting in an atmosphere of reaction gas to obtain the product.

A cyclodextrin-based aza-ordered mesoporous carbon preparation method comprises the following steps that 1, beta-cyclodextrin and a nitrogen source are added into a sulfuric acid solution, and stirred under room temperature; 2, a template agent is added and stirred to be uniform, and two-time heating and heat preservation are performed to obtain a black solid a; 3, beta-cyclodextrin and a nitrogen source are added into a sulfuric acid solution and stirred to be uniform, then, the black solid a is added, the heating and heat preservation process is repeatedly executed, and a black solid b is obtained; 4, the black solid b is roasted in the nitrogen atmosphere, then, a HF acid or NaOH water solution is used for removing the template agent, filtering is performed, a filter cake is dried, and nitrogen-doped ordered mesoporous carbon is obtained. The method has the advantages that the raw materials are cheap and easy to obtain, the specific area of the obtained nitrogen-doped ordered mesoporous material is large, the morphology is in order, the aperture is large, the nitrogen-doped ordered mesoporous carbon can be used as a non-metal catalyst for selective oxidation of ethylbenzene and benzyl alcohol, the ethylbenzene conversion rate can reach 98.7%, and the benzyl alcohol can also reach 88.9%.

The invention provides an anti-pilling antistatic wool fabric conditioning agent, which is composed of the following components in parts by weight: 18 to 25 parts of ethyl acrylate, 15 to 20 parts of polyoxyethylene octyl benzyl alcohol, 6 to 10 parts of stearamide, 5 to 8 parts of magnesium stearate, 3 to 6 parts of sodium sulfate, 2 to 4 parts of glycol, 2 to 4 parts of potassium tartrate, 2 to 4 parts of sodium carboxymethyl starch, 1 to 3 parts of sodium dihydrogen phosphate, 70 to 80 parts of ethanol, and 350 to 400 parts of water. The invention further provides a preparation method of the conditioning agent. The conditioning agent improves the anti-pilling grade of wool fabric by two levels or more, and at the same time the hydrophilicity of the wool fabric is basically not affected. Moreover, the wool fabric processed by the conditioning agent is antistatic, and thus the conditioning agent has a very good antistatic effect.

The invention discloses novel oxazolidine, a preparation method, application, and mono-component polyurethane waterproof paint. The novel oxazolidine is named as 4-mehtyl-3-(2-phenylcarbinol)-1,3-oxazolidine. The novel oxazolidine is used as a latent curing agent of the mono-component polyurethane waterproof paint. During the production process of the waterproof paint, the novel oxazolidine is added into the raw materials, one naked hydroxy group of the novel oxazolidine will react with the polyurethane prepolymer formed by the raw materials, thus the novel oxazolidine is grafted to the polyurethane prepolymer, and the novel oxazolidine (latent curing agent) can be more evenly dispersed in the waterproof paint. If the waterproof paint is stored for a long time, the grafted novel oxazolidine will be dissolved out continuously, the stability of the waterproof paint is improved, the latent curing effect is improved, and avoided is the phenomenon that the latent curing agent is precipitated from the mono-component polyurethane waterproof paint or the latent curing agent aggregates in the waterproof paint. After the waterproof paint is used, the quality of the film formed by the waterproof paint is improved.

The invention relates to a preparing method of triangular flaky nanometer silver particles. The preparing method comprises the following steps that S1, silver trifluoroacetate, PVP (polyvinyl pyrrolidone) and phenylcarbinol are placed into a reaction kettle and are mixed, and a mixture is obtained after the materials are uniformly stirred; S2, metal salts are added into the mixture, and settled solution is obtained through stirring at room temperature; S3, the settled solution is heated to 120 to 150 DEG C in the reaction kettle, the reaction lasts a period of time, and a reaction product is obtained; S4, reaction products are subjected to centrifugal separation and are washed, and then, the triangular flaky nanometer silver particles are obtained. The preparing method provided by the invention has the advantages that the process is simple and convenient, the cost is low, and the preparing method is suitable for large-scale production.