The invention relates to the technical field of medicines, in particular to a preparation method and application of heart tonifying pills. The preparation method comprises the following steps: crushing red
ginseng, safflower,
radix aconiti lateralis praeparata (black prepared common monkshood
daughter root) and pseudo-
ginseng, performing enzymolysis with compound
enzyme, and inactivating to obtain an extract A; crushing
venenum bufonis and pearls, mixing the crushed
venenum bufonis and pearls with ox horn tip
powder, and performing enzymolysis and inactivation with
papain to obtain an extract B; combining the extract A and the extract B, adding beta-
glucosidase for enzymolysis, inactivating, filtering, and concentrating and
drying filtrate to obtain an extract C; after
calculus bovis factitius, artificial musk,
borneol and
benzoin are fully dissolved, a
sodium alginate solution and a
chitosan solution are added, stirring and
freeze drying are conducted, and a component D is obtained; and mixing the extract C and the component D, adding
starch, uniformly stirring, pelleting,
drying,
coating with
activated carbon, and
polishing to obtain the
traditional Chinese medicine composition. The heart-tonifying
pill prepared by the preparation method disclosed by the invention has better effects of reducing
blood pressure and blood fat than heart-tonifying pills prepared by a
pharmacopoeia method and other contrast agents.