67results about "Carbonyl compound separation/purification" patented technology

This application discloses an acetaldehyde recovery device and method in the production of 1,3-butanediol, belonging to the field of fine chemicals. The device includes: a feed pump, a preheater, a distillation column, a falling film reboiler, a bottom circulating pump, a bottom cooler, a top primary condenser, a reflux ratio distributor, a top secondary condenser, a top product tank, a top transfer tank, a bottom product tank, a bottom transfer tank, a vacuum condenser, a vacuum pump inlet separator, a high vacuum unit, and a vacuum pump outlet separator. The horizontal condenser is directly installed at the top of the distillation column, giving it advantages such as simple structure, convenient operation, low pipeline loss, and high vacuum. A method for acetaldehyde recovery in the production of 1,3-butanediol using this device is also disclosed. Compared to existing technologies, this invention uses falling film evaporation combined with vacuum deep cooling, which avoids the thermal decomposition of 3-hydroxybutyraldehyde and achieves low-temperature, high-efficiency acetaldehyde recovery. It is suitable for continuous production.

This invention relates to a cytochrome P450 oxidase STO1, its encoding gene, and its applications. This invention is the first to clone and identify a cytochrome P450 oxidase gene, STO1, from potato responsible for catalyzing the synthesis of spirogelothoraxone, and to determine the nucleotide sequence and translated amino acid sequence of this gene. This invention provides expression vectors, recombinant microorganisms, or transgenic cell lines containing this gene. This invention constructs an engineered Saccharomyces cerevisiae strain for producing spirogelothoraxone, in which the strong promoter ERG9 is replaced by the weak promoter HXT1 in the strain's genome, and the STO1, AtCPR, tHMG1, and STS genes are integrated. This invention also provides a method for constructing this engineered strain and a method for producing spirogelothoraxone using this engineered strain, which can be used for the preparation of spirogelothoraxone.

A method for producing a higher alcohol from a waste plastic feedstock is disclosed, comprising: (a) providing a hydrocarbon feed stream comprising a pyrolysis oil feed obtained from pyrolysis of plastic waste, wherein the pyrolysis oil comprises at least 20 wt % higher olefins with a carbon number in the range C5-C20, based on its total hydrocarbon content; (b) contacting the hydrocarbon feed stream with synthesis gas under hydroformylation conditions in the presence of a hydroformylation catalyst and recovering a hydroformylation product; (c) subjecting the hydroformylation product to hydrogenation and / or a distillation to recover a higher alcohol product.

The application discloses a prenylated polyketide compound, a preparation method and application thereof, and the prenylated polyketide compound is separated from rice fermented with Xylaria nigriplicata. The neuroprotective effect of the prenylated polyketide compound on glutamate-induced excitotoxicity of PC12 cells is clarified through comprehensive evaluation of cell viability, apoptosis and key oxidative stress markers.

Methods and systems for the production of acetone from cumene hydroperoxide (CHP) are disclosed. The disclosed methods involve cleaving CHP to form a cleavage product stream. In some embodiments, the cleavage product stream is separated into an overhead stream and a bottoms stream. The bottoms stream is neutralized, washed, and then processed in a crude acetone column to provide a crude acetone stream. The overhead stream of the cleavage product is flashed forward in the method, bypassing neutralization, washing, and the crude acetone column, and then combined with the crude acetone stream. The combined acetone stream is provided to an acetone product column. According to some embodiments, the acetone product column includes a side draw for obtaining a recycle acetone stream, which is recycled to the cleavage reactor(s). The recycle acetone side draw can be located lower on the acetone product column than the point at which product acetone is obtained. The disclosed methods improve process efficiency.

Provided is a composition capable of suppressing generation of a trimer even when an aliphatic aldehyde at a high concentration of 90 mass% or more is stored at a low temperature. The composition contains 90 mass% or more of an aliphatic aldehyde having 8-16 carbon atoms and 100 ppm or more and 1 mass% or less of an additive with respect to the mass of the aliphatic aldehyde, wherein the additive is one or more selected from the group consisting of polyalkylene glycol derivatives represented by formula (I), sorbitan fatty acid esters, polyoxyethylene sorbitan fatty acid esters, polyoxyethylene sorbitol fatty acid esters, amino acids represented by formula (II), anthranilic acid esters represented by formula (III), and pyrazine derivatives represented by formula (IV).

This invention provides a plant growth regulatory activity of a new biologically active synthetic molecule methanone-(3′,4′,5′-trimethoxy) phenyl, 1-naphthyl, 2-O-4″-ethyl but-2″-enoate. More particularly, the invention relates to the potent plant growth promoting activity of a gallic acid derivative having a structure represented by Formula 1 and a molecular formulae C26H26O7. This invention also provides a novel process for preparation of said molecule from a naturally occurring compound and testing it for growth regulating activity using Bacopa test system developed at CIMAP (Khanuja et al., 2001).

The present invention relates to a method for preparing 3-methyl-2-butenal (prenal), 3-methyl-2-buten-1-ol (prenol), diprenyl acetate of prenal, and 3,7-dimethyl-octa-2,6-dienal (citral), wherein the aldehyde content in one or more reaction flows is maintained below a threshold. Furthermore, the present invention relates to available product flows of prenal, prenol, diprenyl acetate of prenal, and citral.

The application provides a method for preparing 3-hydroxypropionaldehyde by reaction extraction, comprising the following steps: loading a catalyst into a reactor, simultaneously pumping a reaction raw material and an extractant into the reactor in countercurrent, and performing a hydration reaction; the reaction raw material comprises an aqueous propylene acid solution. The method for preparing 3-hydroxypropionaldehyde by reaction extraction separates the hydration product 3-hydroxypropionaldehyde in time during the hydration reaction, moves the hydration reaction to a forward reaction direction, increases the overall yield of 3-hydroxypropionaldehyde, reduces the water content in the product, and further reduces the difficulty of subsequent separation, and compared with direct water evaporation, the energy consumption is significantly reduced. Meanwhile, maintaining a high water / aldehyde ratio can accelerate the hydration reaction rate, effectively reduces the generation of by-products, and further reduces the production cost.

This invention relates to a control method and system for an acetaldehyde distillation column, belonging to the field of chemical separation technology. It includes acquiring tray numbers, anhydrous copper sulfate test paper numbers, and detection time; responding to a moisture content detection signal, controlling the anhydrous copper sulfate test paper corresponding to each test paper number to perform detection according to the detection time; acquiring test paper images of the anhydrous copper sulfate test paper corresponding to each test paper number; analyzing the test paper images to obtain color values, and extracting depth values ​​from the color values; selecting high-purity anhydrous copper sulfate test paper numbers with depth values ​​less than a preset depth threshold, and generating high-purity anhydrous copper sulfate test paper number groups based on these numbers; obtaining corresponding tray number groups based on the high-purity anhydrous copper sulfate test paper number groups; and controlling the trays corresponding to the tray number groups to be stored according to a storage mode. This invention improves the production efficiency of acetaldehyde.

The application provides a continuous preparation method of beta-ionone. By introducing steam into a desolventizing tower, the content of impure ketone can be effectively controlled, the operation flexibility of the whole process can be improved, and the purity requirement of raw material pseudoionone is reduced.

The present disclosure provides methods and systems for capturing carbon dioxide. An example system includes: a pyrolysis device configured to produce syngas and bio-oil from biomass; a power generator configured to produce electricity by combusting at least one of the syngas or the bio-oil; and a carbon capture system configured to use the electricity to capture carbon dioxide from a gas.

The present invention relates to a continuous liquid-phase synthesis process for isophorone by alkaline autocondensation of acetone, comprising the following successive steps: a) continuous injection through a tubular reactor (R) of a stream of an aqueous solution of alkali hydroxide and a stream of an organic solution comprising acetone and by-products recycled via step g); b) condensation reaction of acetone within the tubular reactor (R); c) distillation of the reaction mixture from the tubular reactor (R); d) separation of the concentrated crude reaction from the distillation of step c) leading to an alkaline aqueous phase and an organic phase containing isophorone; e) distillation of the organic phase containing isophorone recovered in the previous step; f) distillation of the polycondensation by-products from the column foot (D2) from the previous distillation.then g) recycling of the stream from the column head of the previous distillation (D3) including xylitones and / or isoxylitones to the tubular reactor (R). [Fig. 1]

This invention discloses a green and energy-saving formaldehyde production system and method. Methanol is fed into a methanol buffer tank, then sequentially preheated in a dehydrogenation feed preheater, a dehydrogenation evaporator, and a first preheater to 210-260°C. After being heated, it enters the dehydrogenation reactor for a dehydrogenation reaction in the presence of a catalyst. The reaction liquid sequentially enters the first preheater and the dehydrogenation feed preheater to recover heat, and then sequentially enters a condenser and a dehydrogenation separator for gas-liquid separation. The liquid phase sequentially enters a preheater, a dryer, a light tower, and an aldehyde tower for separation to obtain formaldehyde product. The remaining liquid enters an alcohol tower to recover formaldehyde. The gas phase sequentially enters a dehydrogenation condenser, a compressor, and a pressure swing adsorption unit to obtain hydrogen. This invention produces hydrogen as a byproduct, which is used as an energy output, making it a green and energy-saving production process. Furthermore, the addition of water vapor reduces the occurrence of side reactions such as dimethyl ether and carbon buildup.

This invention belongs to the field of pharmaceutical technology and discloses a spirocyclic triterpenoid compound, its preparation method, and its application in the preparation of antidiabetic drugs. This invention uses the whole herb of *Euphorbia humifusa* as the isolation target and employs an efficient and systematic separation and preparation method to enrich terpenoid compounds. A spirocyclic triterpenoid compound was obtained through silica gel, ODS column chromatography, and HPLC. In vitro inhibition of α-glucosidase experiments confirmed that compound I has significant hypoglycemic activity and can be used as an active ingredient in antidiabetic drugs, with broad applications.

The application provides a method for preparing anti-caking 1,3-cyclohexanedione, which comprises the following steps: (1) in a solvent, resorcinol sodium salt and hydrogen are subjected to hydrogenation reaction under the action of a catalyst, and after the reaction is completed, the catalyst is removed by filtration to obtain a hydrogenation solution; (2) an anti-caking agent is added into the hydrogenation solution to obtain a reaction solution containing the anti-caking agent; (3) acid is added into the reaction solution containing the anti-caking agent to obtain an acidified solution; and (4) the acidified solution is filtered to obtain a wet product, and the wet product is dried to obtain 1,3-cyclohexanedione finished product. The method does not need to additionally increase new equipment and does not additionally increase equipment cost. The method is simple in process, small in change to the original process and strong in operability. The 1,3-cyclohexanedione product is active in nature, and is easily deteriorated if not properly handled, thereby affecting the use of downstream customers. The method does not affect the quality of the product after the use of the anti-caking agent, and does not affect the use of downstream customers.

The present invention relates to a process for preparing methacrolein starting from formaldehyde and propionaldehyde in the presence of a homogenous catalyst mixture. The obtained reaction mixture is partially transferred into a first distillation column which comprises at least one column internal. The reaction mixture is introduced into the first distillation column partially above the at least one column internal and partially below the at least column internal.

The present invention relates to a method for synthesizing pterosin D using an ammonia-based reducing agent, and more specifically, to a method for synthesizing pterosin D by dissolving a 5-(2-hydroxyethyl)-2,2,4,6-tetramethyl-1H-indene-1,3(2H)-dione compound in an ether solvent and then adding an ammonia-based reducing agent thereto. In addition, the method for preparing pterosin D according to the present invention enables the production of pterosin D with high yield and excellent purity, and is suitable for mass production, thereby being useful for drug research and pharmaceutical production based on pterosin D.

The application provides a method for preparing anhydrous formaldehyde from formaldehyde aqueous solution. The method comprises the following steps: adding C5-C10 straight-chain aliphatic alcohol into the formaldehyde aqueous solution, reacting at 50-100 DEG C under normal pressure for 1-3 hours to generate formaldehyde hemiacetal; the molar ratio of formaldehyde to the reaction agent is 1:1.0-1.5; adding an extractant into the reaction solution, and standing to separate into upper and lower layers; the upper layer is an organic phase containing the formaldehyde hemiacetal, the reaction agent and the extractant, and the lower layer is an aqueous phase; the extractant is at least one selected from n-pentane, n-hexane, cyclohexane and toluene; the mass ratio of the reaction agent to the extractant is 1:0.4-0.6; rectifying the organic phase to obtain the formaldehyde hemiacetal; and pyrolyzing the formaldehyde hemiacetal and absorbing the formaldehyde hemiacetal with methanol and / or ethanol to obtain a small-molecule alcohol solution of anhydrous formaldehyde. The technical problem to be solved is how to significantly reduce the dehydration energy consumption, improve the formaldehyde recovery rate and simplify the operation process under the premise of ensuring the purity of the anhydrous formaldehyde.

The present application relates to the technical field of octanol production, and discloses an octanol production system and a production method. The system comprises an aldol condensation device, an oil-water separation device, a dealkali tower and a hydrogenation device which are connected through pipelines. The aldol condensation device is used for aldol condensation reaction of n-butyraldehyde and sodium hydroxide to obtain an aldol condensation reaction product. The oil-water separation device is used for oil-water separation of the aldol condensation reaction product to obtain a dehydrated aldol condensation reaction product containing sodium hydroxide, and the content of sodium hydroxide in the dehydrated aldol condensation reaction product is higher than 5 ppm. The dealkali tower is arranged between the oil-water separation device and the hydrogenation device, and is used for dealkali treatment of the dehydrated aldol condensation reaction product to obtain a de-sodium-hydroxide aldol condensation reaction product. The hydrogenation device is used for hydrogenation reaction of the de-sodium-hydroxide aldol condensation reaction product. The system can ensure the purity of the target product while improving the colority of the target product.

The present application relates to a kind of new aromatic heteroterpene compound solenopsin A, it has significant bacteriostatic effect on fusarium graminearum, fusarium oxysporum and fusarium sambucinum, can be used to prepare anti-agricultural plant pathogenic fungi drug, with good medicinal prospect.

The application discloses a gas phase side line variable pressure rectification heat integration device and method, which realizes high-purity separation of butanone-isopropyl alcohol-n-heptane ternary azeotrope at lower energy consumption and equipment cost by using gas phase side line, heat integration and variable pressure rectification technology; the ternary azeotrope enters a medium-pressure rectification tower, and butanone products with a purity of 99.9% are separated at the bottom; overhead distillate and a gas phase side line stream enter a high-pressure rectification tower, and n-heptane products with a purity of 99.9% are obtained at the bottom; overhead distillate and a gas phase side line stream enter a low-pressure rectification tower, and isopropyl alcohol products with a purity of 99.9% are obtained at the bottom; overhead distillate is recycled to the medium-pressure rectification tower; heat integration is carried out between the medium-pressure rectification tower and the high-pressure rectification tower; compared with a conventional variable pressure rectification process, the process has the advantages of high separation efficiency, low energy consumption and equipment cost, and has strong competitiveness in industrial application.

The invention relates to a process for the preparation of methylpropenal from formaldehyde and propylaldehyde in the presence of a homogeneous catalyst mixture. The resulting reaction mixture is partially transferred into a first distillation column comprising at least one column internal. The reaction mixture is partially introduced into the first distillation column above the at least one column internal and partially below the at least one column internal.

A highly efficient method for extracting 6-gingerol involves drying fresh ginger, mixing it with micronized silica gel, and pulverizing it into a powder. The powder is then added to an extraction solvent prepared from ethanol, glycerol, CTAB, and vitamin C, followed by ultrasonic extraction to obtain the extract. In this invention, micronized silica gel is added to the raw material, and the extraction solvent is prepared using ethanol, glycerol, CTAB, and vitamin C. During low-temperature ultrasonic extraction, the difficulty in extracting antioxidant components from dried ginger is solved, effectively improving the transfer rate and yield of 6-gingerol. The transfer rate of 6-gingerol from dried ginger reaches 77.8%, and the yield reaches 43.6%. Subsequently, during purification, a purification solvent composed of diethyl ether and n-hexane is used, effectively improving the purity of the product; the purity of 6-gingerol reaches 98.6%.

A process for preparing isopropanol by hydrogenating acetone includes the steps of (1) introducing an acetone raw material into an acetone pre-oxidation processor to preoxidize impurities to obtain a pre-oxidized acetone raw material; and (2) introducing the acetone raw material after the pre-oxidation treatment and an optional intermediate treatment into an acetone hydrogenation reactor to conduct a hydrogenation reaction to obtain a crude isopropanol product.

Disclosed is a method for the hydroformylation of olefins including 2 to 8 carbon atoms, whereby (i) reacting an inflow containing olefins and an added saturated hydrocarbon comprising 2 to 8 carbon atoms, as well as carbon monoxide and hydrogen, fed into a reaction zone and reacted in the presence of a hydroformylation catalyst, (ii) separating a flow consisting partly of unreacted olefins and saturated hydrocarbons from the discharge from the reaction zone, (iii) separating said flow into an olefin-enriched fraction and an olefin-depleted fraction by means of an olefin-selective membrane, and (iv) removing the olefin-enriched fraction is at least partially redirected into the reaction zone.

This invention belongs to the field of biomedical technology and discloses a cyclohexanone-derived polyketide compound, its preparation method and application. It provides ten cyclohexanone polyketide compounds, including: amorocoelone A (1), amorocoelone C (2), (4R,5S,6R,9R,10R)-4,9,10-trihydroxy-6-methyl-3-methylene-2-oxaspiro[4.5]dec-7-en-1-one (3), massarilactone A (4), massarilactone C (5), massarilactone E (6), amorocoelone H (7), amorocoelone I (8), (R)-1-hydroxy-1-(5-hydroxy-2-methylphenyl)propan-2-one (9), paraverrucsin A (10), wherein compounds (1), (2), (7) and (8) are new compounds. These compounds can be prepared by bio-fermentation, which has a short production cycle and is environmentally friendly. At the same time, the compounds have anti-influenza virus activity and can be used to prepare antiviral drugs, which has extremely high medical and commercial value. The method has the advantages of short cycle, mild culture conditions, few by-products, strong stereoselectivity, and low cost. It also has high economic value, is low-cost, easy to operate, and easy to produce on a large scale, providing a new way to obtain polyketide compounds containing cyclohexanone structural units from natural sources.

The application discloses a natural sesquiterpene compound with an agricultural pathogenic bacteria resisting effect and a preparation method and application thereof. A novel natural sesquiterpene compound is separated from stems of diseased Gordonia aculeata. Activity experiments show that the natural sesquiterpene compound has the agricultural pathogenic bacteria resisting effect, has good antibacterial activity on plant pathogenic bacteria Rhizopus stolonifer, Verticillium dahliae Kleb, Thanatephorus cucumeris and Fusarium oxysporum, and can be applied to plant disease prevention and treatment as an agricultural fungicide.

The present disclosure provides methods and systems for capturing carbon dioxide. An example system includes: a pyrolysis device configured to produce syngas and bio-oil from biomass; a power generator configured to produce electricity by combusting at least one of the syngas or the bio-oil; and a carbon capture system configured to use the electricity to capture carbon dioxide from a gas.

The present application relates to the chemical technology field, specifically to a method for synthesizing vanillin and ortho-vanillin by one-step method, which uses o-methoxyphenol as starting material, and carries out one-step reaction with formaldehyde under the action of composite catalyst, and then separates vanillin and ortho-vanillin by post-treatment of the reaction solution. By using the composite catalyst with specific composition, the present application realizes high-selectivity formylation of formaldehyde at the ortho position of the hydroxyl group of o-methoxyphenol, increases the generation proportion of ortho-vanillin from the source, avoids the use of toxic reagent, and has mild reaction conditions. By using the difference in solubility of specific mixed solvent system and adjusting the temperature, the present application can efficiently separate vanillin and ortho-vanillin, and solves the separation problem caused by the similar properties of isomers in the prior art. The overall process is simple and efficient, and the yield and product purity are significantly improved, which has excellent industrial application prospect.