1396results about "Carbonyl compound separation/purification" patented technology

The invention discloses a low-cost and environment-friendly process for producing 1, 4-bis (4-fluorobenzoyl) benzene, and belongs to the technical field of Friedel-Craft reaction, fluorobenzene and paraphthaloyl chloride react to generate 1, 4-bis (4-fluorobenzoyl) benzene, after reaction quenching, filtering is performed to obtain a crude product 1, 4-bis (4-fluorobenzoyl) benzene and filtrate, and the 1, 4-bis (4-fluorobenzoyl) benzene is purified in a sublimation crystallization mode; standing and layering the filtrate in an inclined plate layering device, respectively treating an oil layer and a water layer, dehydrating a fluorobenzene layer in a dehydrating tower, and returning fluorobenzene; the water phase is firstly subjected to organic matter removal treatment, the obtained organic matter enters a fluorobenzene recovery device to be sleeved back, and the obtained water phase is a byproduct of crystallized aluminum chloride in an evaporative crystallization device. According to the process, the 1, 4-bis (4-fluorobenzoyl) benzene is produced in a sublimation crystallization mode instead of a solution crystallization mode, no waste solvent is generated, the waste solvent does not need to be recycled, the cost is low, organic matter removal and evaporative crystallization treatment is carried out on wastewater, organic matter recycling is carried out, crystalline aluminum chloride is produced as a byproduct, and wastewater and waste salt are not discharged.

The invention belongs to the technical field of chemical production, and particularly relates to an efficient energy-saving refining system for producing cyclohexanone through dehydrogenation, which comprises an alcohol tower, a dehydrogenation heat exchanger, a dehydrogenation reactor, an alcohol tower feeding heat exchanger, a dehydrating tower, a light tower I, a light tower II, a ketone tower and an alcohol recovery tower which are connected in sequence, a middle feeding port of the alcohol tower is communicated with a tube pass discharging port of the alcohol tower feeding heat exchanger, a top discharging port of the alcohol tower is communicated with a tube pass feeding port of the dehydrogenation heat exchanger, a bottom discharging port of the alcohol tower is communicated with a middle feeding port of the alcohol recovery tower, and an alcohol ketone drying tower is additionally arranged between the alcohol tower feeding heat exchanger and the dehydration tower. A feed port of the alcohol ketone drying tower is communicated with a shell pass discharge port of the alcohol tower feed heat exchanger, and a liquid phase discharge port of the alcohol ketone drying tower is communicated with an upper feed port of the dehydrating tower. The alcohol tower adopts a process that raw materials directly enter the tower top, tower top reflux is cancelled, steam consumption is reduced, and the purpose of saving energy is achieved.

The invention relates to the technical field of chemical separation, in particular to a cyclohexanone rectification and purification method based on high-tower segmented packing, which comprises the following steps: step 1, filtering a cyclohexanone raw material containing impurities to remove solid particles, and dynamically adjusting the filtering precision according to the viscosity of the raw material; 2, arranging a bottom section, a middle section and a top section in the vertical high tower; the temperature gradient of each section is regulated and controlled through an independent temperature control unit, so that the temperature gradient of the middle section is matched with the relative volatility of the cyclohexanone-light component; 3, dynamically adjusting the reflux ratio based on the real-time detection result of the purity of the tower top distillate, and controlling an intermittent discharge valve according to the density change of the tower bottom heavy component enrichment liquid so as to continuously remove the heavy components; and 4, recycling the waste heat of the steam at the top of the tower for preheating the raw materials, and inhibiting the tower pressure fluctuation through a buffer tank. Through the innovative design of sectional packing of the high tower, the separation efficiency is improved, the energy consumption is reduced, and meanwhile, the equipment reliability is improved.

The invention discloses a method for extracting curcumin from turmeric, which comprises the following steps: adding a deep eutectic solvent solution into turmeric powder, adding pectinase, uniformly mixing, adding terpilenol, performing magnetic stirring extraction and centrifugation, and taking an upper solution, thereby obtaining the curcumin. According to the method, a solvent system combining a deep eutectic solvent (DES), pectinase and terpilenol is adopted, extraction and enrichment of curcumin in turmeric can be achieved through a simple one-step method, the process is greatly simplified, recycling and reutilization of reagents are achieved, and compared with an existing extraction method, the extraction method has the advantages of being easy to operate, green, environmentally friendly, high in yield and the like. The method is short in extraction time, low in production cost and suitable for large-scale industrial production.

The invention provides a separation method of a catalyst for preparing butyraldehyde through propylene carbonylation, and relates to the technical field of chemical synthesis. The separation method comprises the following steps: carrying out flash evaporation separation and low-pressure evaporator evaporation on a material obtained by carrying out a propylene carbonylation reaction on propylene and synthesis gas as raw materials, obtaining a gas-phase material from a collecting tank of a low-pressure evaporator, and outputting a liquid-phase catalyst solution; the gas-phase material is subjected to condensation and gas-liquid separation, crude butyraldehyde is output, and obtained non-condensable gas returns to a liquid distribution chamber of the low-pressure evaporator; wherein the catalyst is acetylacetone triphenyl phosphorus silicification carbonyl rhodium, and the operation temperature of the low-pressure evaporator is 85-95 DEG C. By controlling the circulating air volume and the evaporation temperature, high-temperature deactivation of the catalyst is prevented, the service life of the catalyst is prolonged, and the process cost is reduced; the process flow is simplified, and the method is suitable for large-scale process production.

The invention belongs to the field of synthesis of organic matters, and particularly relates to a synthesis method of 4-oxo-beta-ionone, which comprises the following steps: S1, dissolving beta-ionone in a good solvent, and introducing sulfur dioxide; s2, adding water and a catalyst into the solvent, and then adding an oxidizing agent; s3, removing a water phase, and adding an alkaline solution; s4, separating a water phase, recovering the solvent, and distilling to obtain 4-oxo-beta-ionone; according to the method, the beta-ionone is oxidized into the 4-oxo-beta-ionone by using the oxidizing agent, and the sulfur dioxide is introduced to protect conjugated double bonds on a six-membered ring in the beta-ionone before the oxidizing agent is added, so that the oxidation selectivity of the oxidizing agent is improved, and the oxidation efficiency is high.

The utility model relates to a low-temperature decompression continuous catalytic rectifying tower for synthesizing diacetone alcohol, which comprises a catalytic rectifying tower, a condenser and a built-in reboiler, the catalytic rectifying tower comprises a reaction section and a stripping section, and a feed port of the catalytic rectifying tower is positioned between the reaction section and the stripping section. The external condenser is arranged at the tower top of the catalytic rectifying tower, the inlet end of the condenser is connected with a tower top outlet of the catalytic rectifying tower, the outlet end of the condenser is connected with a tower top side inlet of the catalytic rectifying tower, the built-in reboiler is arranged at the tower bottom of the catalytic rectifying tower, and a tower kettle extraction port is formed in the bottom of the catalytic rectifying tower. According to the utility model, not only is the reaction conversion rate (gt: 99.9%) obviously improved, but also the reaction selectivity reaches 100%, the generation of byproducts and the decomposition of diacetone alcohol are avoided, the reaction energy consumption is reduced, in addition, the product does not need to be subsequently separated, and the catalyst does not need to be separated and recycled.

The invention provides a device and a method for removing MIBK (methyl isobutyl ketone) in raffinate for extracting and separating zirconium and hafnium, the device comprises a tank body, a liquid distribution ring is fixedly connected in the tank body, one side of the liquid distribution ring penetrates through the tank body and is outwards communicated with a feeding pipe, a plurality of spray heads are arranged below the liquid distribution ring in a penetrating manner, the outer end of the tank body is fixedly connected with a bracket, and the bracket is fixedly connected with a rotating shaft. According to the device, raffinate can be quickly conveyed into the tank body by arranging a liquid distribution ring and a spray head, rotation of a rotating shaft and a rotating plate can be completed in cooperation with a gear assembly, the fallen raffinate is scattered, it is ensured that the raffinate can uniformly fall on a steam heating pipe, and the raffinate is uniformly heated; meanwhile, the contact area of the gas phase and the liquid phase can be increased in cooperation with the condensation assembly, the phase splitting barrel and the grid plate, the MIBK separation efficiency is improved, and the purpose of rapidly removing oil is achieved through the principle that the volatility is affected by factors such as liquid diffusion and temperature.

The invention discloses a separation method of a phenol-cyclohexanone azeotropic system, a separation system and application. The separation method comprises the following steps: separating a material containing phenol, cyclohexanone and impurities and a material containing an extraction agent in an extractive distillation tower, and extracting the material containing cyclohexanone from the tower top; extracting a material containing phenol, impurities and an extracting agent from the tower kettle; the impurities comprise at least one of cyclohexylbenzene, ketal and a ketal dehydration product; feeding the material containing phenol, impurities and the extraction agent into a solvent recovery tower for separation, and extracting the material containing phenol from the tower top; a material containing the extraction agent and impurities is extracted from the side line of the tower and is cooled and separated by a phase splitter to obtain a light-phase material containing the impurities and a heavy-phase material containing the extraction agent; the heavy-phase material containing the extraction agent flows back to the solvent recovery tower and then flows back to the extractive distillation tower, so that recycling of the extraction agent is realized, the investment economic cost of the extraction agent is effectively saved, and the condition that the extraction agent needs to be regularly discharged as fuel or post-treated in the prior art is avoided.

The invention provides an automatic step-by-step melting purification system for high-purity 4, 4 '-difluorobenzophenone, which comprises a primary crystallization system, a secondary crystallization system and a recovery-level crystallization system, the first-stage crystallization system comprises a first-stage crystallizer, a first-stage storage tank and a circulation tank; the second-stage crystallization system comprises a second-stage crystallizer, a second-stage storage tank and a finished product tank; the recovery-level crystallization system comprises a recovery-level crystallizer, a recovery storage tank and a waste liquid tank; an outlet of the first-stage crystallizer is connected with the first-stage storage tank, the circulating tank and the second-stage storage tank through pumping pipelines respectively; an outlet of the secondary crystallizer is respectively connected with a secondary storage tank, a finished product tank and a circulating tank through pumping pipelines; an outlet of the first-stage storage tank is connected with the first-stage crystallizer through a pumping pipeline; an outlet of the circulating tank is connected with the recycling-level crystallizer through a pumping pipeline; an outlet of the second-stage storage tank is connected with the second-stage crystallizer through a pumping pipeline; the outlet of the recycling-level crystallizer is connected with the first-level storage tank, the circulating tank, the recycling storage tank and the waste liquid tank through pumping pipelines, the whole process is automatic in operation, the safety degree is high, the purification process is low-carbon and environment-friendly, and the requirements of industrial production are met.

The present invention provides a device for refining cyclohexanone by dehydrogenation of cyclohexanol, comprising an alcohol first tower, a dehydrogenation reactor, a dehydrogenation heat exchanger, an alcohol tower feed heat exchanger, a light first tower, a coupled reboiler, a light second tower, a ketone tower, and an alcohol second tower. The device of the present invention redesigns the six-tower process to achieve the refining and separation of cyclohexanol dehydrogenation materials, and couples and utilizes the available heat source and cold source. Using the device of the present invention to purify cyclohexanone can improve the product yield while saving steam consumption, reducing the operating cost of the device, and reducing the discharge of three wastes.

The invention relates to a lignin-based polymer pervaporation membrane, a preparation method thereof and a method for separating and purifying cyclohexane-KA oil. The invention aims to provide a pervaporation membrane which is high in permselectivity, high in stability and good in mechanical property. The pervaporation membrane is used for cyclohexane-KA oil separation and has the advantages of high separation efficiency, low energy consumption and simple process. The preparation method comprises the following steps: adding the surfactant, the polymer and the solvent into a reactor, and stirring at 50-70 DEG C for 4-6 hours to obtain a mixed solution; the method comprises the following steps: adding lignin and a solvent into a reactor, and stirring at room temperature for 4-6 hours to obtain a lignin solution; dropwise adding the lignin solution into the mixed solution, and continuously stirring at constant temperature for 12-24 hours to obtain a membrane casting solution; transferring the membrane casting solution to a centrifugal tube, performing centrifugal separation, and uniformly coating the membrane casting solution on an ultrafiltration membrane material with the membrane thickness of 100-200mm to form a uniform liquid membrane; and drying the liquid membrane to obtain the lignin-based polymer pervaporation membrane. Belongs to the technical field of membrane separation.

A process for purifying a crude cis-2-olefine acid by thermal separation, the process comprising subjecting the crude cis-2-olefine acid to wiped-film evaporation or vacuum distillation under a temperature-reduced pressure curve, thereby minimizing the isomerization of the cis-2-olefine acid to trans-2-olefine acid.

The invention discloses a device and method for separating water and trihydroxy propionaldehyde through heat pump rectification. The device comprises a water recovery tower, a heat exchanger, a trihydroxy formaldehyde water separation tank, a compressor, a tower bottom condenser, a tower top condenser, a water separation tank, a reflux pump and a trihydroxy propionaldehyde recovery tower. By utilizing the characteristic that the temperature of the tower top and the tower kettle of a rectifying tower for separating crude trihydroxy propionaldehyde does not exceed 20 DEG C, a heat pump rectification technology is used, low-grade heat of distillates at the tower top of a water recovery tower is changed into a high-grade heat source through a compressor, heat in the system is fully used through heat integration in the system, and consumption of external public works is reduced. A small amount of power consumption is used, a large amount of steam consumption is saved, and the effect of saving the operation cost of the device is achieved.

The invention belongs to the field of plant endophytic fungus secondary metabolites, particularly relates to a secondary metabolite of fennel endophytic fungus fusarium oxysporum as well as a preparation method and application thereof, and provides a fennel endophytic fungus secondary metabolite with structures as shown in compounds 1-8. Wherein the compound 2 and the compound 7 have inhibitory activity on staphylococcus aureus, escherichia coli, bacillus cereus, bacillus subtilis, candida albicans and shigella, and have a certain inhibitory effect on cervical cancer Hela cell strains.

A technology for preparing glutaraldehyde through cyclopentene oxidation belongs to the technical field of organic synthesis, glutaraldehyde is prepared through cyclopentene oxidation by adopting a photocatalysis-electrocatalysis synergistic catalyst g-C3N4 / TiO2 (at) Au-Co / N-G. The catalyst is of a unique core-shell structure, is stable in property, promotes an oxygen reduction reaction in a catalysis technology, and has good catalytic activity. The conversion rate of cyclopentene and the selectivity of glutaraldehyde are remarkably improved, and the effect is remarkable.

The present invention relates to a method for synthesizing small-sized organic nanocrystals using cadmium telluride quantum dots, and belongs to the field of nano synthesis technology. The method uses functionalized quantum dots as seeds to synthesize organic molecular crystals through a seed growth method, and the synthesized organic nanocrystals have uniform sizes, and the sizes are all around 30nm. The method is simple and universal, and provides a new path for accurately controlling the size of organic molecular crystals.

The invention provides a matrine-natural polyphenol amorphous substance as well as a preparation method and application thereof, and relates to the technical field of polyphenol and alkaloid pharmacy, in the matrine-natural polyphenol amorphous substance, the molar ratio of matrine to natural polyphenol is (1-2): (1-2), through strong interaction between matrine and polyphenol substances, the matrine-natural polyphenol amorphous substance can be used for preparing the natural polyphenol, and the matrine-natural polyphenol amorphous substance can be used for preparing the natural polyphenol. The physicochemical properties of the medicine in the amorphous substance, such as solubility, polarity and lipid-water partition coefficient, are changed, the slow release of the medicine is realized, and the IC50 value of the amorphous substance is reduced; in addition, matrine and polyphenol substances exert synergistic anti-oxidative stress capability, the ROS (reactive oxygen species) level of cells is reduced, and the toxicity of natural polyphenols to the cells is further reduced.

The present invention provides a device and method for distilling and extracting paeonol. The extraction device includes a base, a fixing frame is provided on the base, a distillation mechanism is provided on the fixing frame, and the distillation mechanism includes: a distillation tank, a first horizontal plate and a second horizontal plate are provided in the distillation tank, the second horizontal plate is provided above the first horizontal plate, a plurality of heat transfer pipes are provided between the first horizontal plate and the second horizontal plate, a shielding shell is provided below the first horizontal plate, and a plurality of flame nozzles are provided in the shielding shell. The present invention drives a stirring plate to rotate to a horizontal state, drives a lifting plate to move downward, drives the horizontal stirring plate to move downward to press the medicinal materials in the mixed liquid onto the first horizontal plate, and then squeezes the medicinal materials in the mixed liquid, accelerates the precipitation of paeonol in the medicinal materials, and at the same time, the aeration holes eject gas, aerate the medicinal materials while squeezing them, and accelerates the precipitation of paeonol in the medicinal materials, thereby enhancing the distillation and extraction effect of paeonol.

The invention discloses a silver-method formaldehyde production process, and belongs to the technical field of formaldehyde production, raw material feeding and temperature in the process are strictly controlled, superheated water vapor is supplemented at the stage of an oxidizer, and under the condition that the reaction process is not affected, the temperature of generated aldehyde-containing mixed gas is reduced, and local peroxidation is avoided. And part of formaldehyde is absorbed in the cooling process of the water vapor and returns to the absorption tower as a circulating liquid for further absorption, so that the aldehyde-containing mixed gas can be circularly absorbed step by step. According to the method, superheated water vapor is supplemented, the methanol conversion rate is increased, the yield of formaldehyde is increased, the consumption of methanol is reduced, the process is simple, and cost reduction of silver-method formaldehyde production can be achieved.

Provided are a fluorine-containing compound suitable to produce rubber having both excellent short-term and long-term heat resistance, a fluorine-containing copolymer using such a compound, and a fluorine-containing copolymer composition. A fluorine-containing compound represented by formula (1) below, a fluorine-containing copolymer using such a compound, and a fluorine-containing copolymer composition. In formula (1), R1 to R3 are each independently a hydrogen atom or a fluorine atom; R4 is a hydrogen atom, a fluorine atom, or a C1-8 monovalent organic group free from a carbonyl group; Z is an oxygen atom, a sulfur atom, or -N(R5)- where R5 is a hydrogen atom or a C1-4 monovalent organic group; X is a single bond or a difluoromethylene group; Y1 to Y4 are each independently a fluorine atom or a trifluoromethyl group; and Q is a C1-8 perfluoroalkylene group optionally containing an etheric oxygen atom.

The invention discloses a photoinitiator, an ink composition and application of the photoinitiator, the photoinitiator is 3-methyl-4 '-phenyl benzophenone, the 3-methyl-4'-phenyl benzophenone has specific particle distribution, and the ink composition prepared from the photoinitiator particles has high wear resistance and alcohol resistance.

The invention relates to the technical field of synthesis of organic compounds, and discloses a dibenzoylmethane preparation method, which comprises the following steps: preparation of a functionalized ionic liquid, preparation of a deep eutectic solvent, construction of a composite system, implementation of a condensation reaction, regeneration of catalytic active sites, pH adjustment, crystal separation and the like. According to the method, a temperature-responsive two-phase system formed by the functionalized ionic liquid and the deep eutectic solvent is combined with a catalyst regeneration process and a pH regulation crystallization separation technology, so that the greenization, high efficiency and integration of the dibenzoylmethane synthesis process are realized, the product purity and yield are remarkably improved, and the environmental pollution and the production cost are reduced.

The invention discloses a preparation method of 2-heptanone, and belongs to the technical field of organic synthesis. The 2-heptanone is obtained by taking acetone and n-butyl alcohol as raw materials, toluene as a solvent and cesium carbonate and ruthenium acetylacetonate as catalysts, and the reaction product is separated and purified to obtain the purified 2-heptanone. The preparation method provided by the invention effectively improves the yield of 2-heptanone, and the used raw materials and reagents are environment-friendly and non-toxic; in addition, reaction conditions involved in the preparation method are mild, harsh reaction conditions are not needed, and large-scale application and popularization are facilitated.

The invention belongs to the technical field of medicines, and particularly relates to a flavonoid compound-meglumine co-amorphous substance and a preparation method thereof. The flavonoid compounds comprise baicalein, hesperetin, naringenin, kaempferol, quercetin, isoliquiritigenin and the like, and the co-amorphous substance consists of a single flavonoid compound and meglumine and is prepared by adopting a melting shock cooling method or a rotary evaporation method. The miscibility of the flavonoid compounds and the meglumine is screened through Hansen solubility. The crystal diffraction characteristics, thermodynamic properties and intermolecular interaction of the co-amorphous substance are measured through PXRD, DSC and FTIR, and it is shown that the six flavonoid compounds and meglumine successfully form a co-amorphous system. The solubility and the dissolution rate of the six flavonoid compound-meglumine co-amorphous substance are obviously superior to those of flavonoid bulk drugs, and the physical stability of the formed co-amorphous substance is obviously superior to that of a single amorphous drug, so that the co-amorphous substance shows good patent medicine performance.

The invention relates to a process for extracting alcohols from an initial mixture (1) comprising alcohols in aqueous phase, with:a distillative separation by an isopropanol-butanol distillation column (III) equipped at the top with a condenser (c3), intended for separating said mixture into a water-isopropanol azeotrope stream (6) at the top and into a water-butanol azeotrope stream (7) at the bottom,a distillative separation intended for separating the water-butanol azeotrope stream into water and butanol, by a hetero-azeotropic distillation system comprising at least one water-recovering water column (IV) and at least one butanol (9)-recovering butanol column (V) equipped with a reboiler (r5),such that a heat transfer is performed from the top water-isopropanol azeotrope stream (6) entering the condenser of the isopropanol-butanol distillation column (III), to the stream entering the reboiler of the butanol column (V).

The invention discloses an environment-friendly p-hydroxyacetophenone production process, and particularly relates to the technical field of p-hydroxyacetophenone production, which comprises the following steps: step 1, respectively putting dissolved phenol and acetic anhydride into a synthesis reaction kettle, stirring and heating to 128 DEG C, refluxing for 5 hours at normal pressure, then carrying out heat preservation treatment, and reacting to generate phenyl acetate; 2, cooling phenyl acetate generated by the reaction to 60 DEG C, washing with water, standing for layering, and discharging phenyl acetate to generate a small amount of by-products containing 90% of glacial acetic acid; and 3, pumping the dehydrated phenyl acetate into a reaction kettle by a vacuum pump, gradually adding aluminum trichloride, then adding acidic water for hydrolysis, cooling to 60 DEG C, and discharging to obtain a liquid crude product of p-hydroxyacetophenone and o-hydroxyacetophenone. The environment-friendly performance of implementation is good, conditions needed by the technology are mild, the unstable condition is not prone to occurring in the operation process, and the practical application effect of the method is ideal.

The invention discloses a system device and a method for producing aldehyde compounds through supergravity two-phase hydroformylation. The system device comprises a supergravity reactor, a buffer tank, a first circulating pump, a tower kettle heat exchanger, a circulating heat exchanger, a split-phase tank, a second circulating pump, a crude aldehyde transfer pump, a supergravity rectification unit, a tower kettle reboiler, a product extraction pump and a cold and hot all-in-one machine. According to the system device, under the condition that a polar solvent and a surfactant are not added, the two-phase hydroformylation reaction process can be greatly enhanced through the supergravity reactor, the technological process is shortened, and then a product is separated and purified through the supergravity rectification unit to obtain an aldehyde compound; the problems of low two-phase hydroformylation reaction efficiency, serious self-polymerization in a hydroformylation product purification process and the like in the prior art are solved; by utilizing the method, the olefin conversion rate is more than 90%, the aldehyde selectivity of the product is more than 99%, the purity of the purified product is more than 99%, and the loss amount of the catalyst is less than or equal to 0.5 mg / kg.

The invention provides a method for extracting, rectifying and separating an ethano-2-pentanone azeotropic system by using a tetramethylammonium chloride eutectic solvent, and relates to the technical field of extracting, rectifying and separating the ethano-2-pentanone azeotropic system, which comprises the following steps: taking an ethano-2-pentanone mixture as a raw material to be separated; the method comprises the following steps: mixing and stirring a hydrogen bond acceptor and a hydrogen bond donor according to a certain proportion and temperature to obtain the eutectic solvent, firstly heating a material S01 to be separated by a heat exchanger E101 and then entering the middle part of a T101 tower, adjusting a eutectic solvent material flow S02 to a proper temperature and then entering the upper part of the T101 tower, carrying out heat exchange on a tower top ethanol material flow S03, enabling a part of material flow S05 to flow back to the tower top, and carrying out heat exchange on a tower top ethanol material flow S03; according to the method, a specific eutectic solvent is adopted as an extracting agent, an extractive distillation process is matched, an ethano-2-pentanone azeotropic system can be effectively broken, the yields of ethanol and 2-pentanone can reach 99% or above finally, the purities of ethanol and 2-pentanone can reach 99.5% (mass percent) or above finally, and efficient separation is achieved.