665results about "Preparation from heterocyclic compounds" patented technology

Processes and reactor systems are provided for the conversion of oxygenated hydrocarbons to hydrocarbons, ketones and alcohols useful as liquid fuels, such as gasoline, jet fuel or diesel fuel, and industrial chemicals. The process involves the conversion of mono-oxygenated hydrocarbons, such as alcohols, ketones, aldehydes, furans, carboxylic acids, diols, triols, and/or other polyols, to C₄₊ hydrocarbons, alcohols and/or ketones, by condensation. The oxygenated hydrocarbons may originate from any source, but are preferably derived from biomass.

The present invention provides a method for the production of glycolaldehyde with high specificity. The hydrous thermolysis consists of the spraying of aqueous sugar solutions containing from 25 to 80% of water but preferably 30 to 60% water, as a fine mist into a reactor held at the between 500 and 600° C., but preferably between 520 and 560° C. and the condensation of the resulting vaporous product in a surface condenser with optional heat recovery. The residence time of the vaporous product in the reactor should be in the range 0.1–5 seconds, but preferably in the range 0.5 to 2 seconds. Aldose monomeric sugars, preferably glucose (also known as dextrose), are preferred for use in the aqueous solution. The yield of glycolaldehyde in the condensed liquid is minimum 50% by weight of the sugar fed for glucose solutions.

This invention provides redox-active molecules attached to polypodal (e.g., bipodal, tripodal, quadrapodal, pentapodal, etc.) tethers that can be used for attachment of the redox-active molecules to a substrate (e.g., an electrode). The tethered redox-active molecules are useful for the fabrication of memory devices.

The invention relates to a method for preparing aromatic hydrocarbon and cyclopentenone from biomass derivative gamma-valerolactone by catalytic conversion, which comprises the following steps: (1) using biomass derivative gamma-valerolactone as a raw material, which is prepared by carrying out hydrogenation reaction on levulinic acid; (2) introducing one or more transition metals into a zeolite molecular sieve, and preparing a reaction catalyst at the reaction temperature of 350-550 DEG C by using a fixed bed or fluid bed as a reactor; (3) in an inert or reducing atmosphere, carrying out contact reaction on the raw material gamma-valerolactone and catalyst under the reaction pressure of 0-10 MPa; and (4) after the pyrolysis gas is condensed, collecting the liquid product in the condensation receiver, thereby obtaining the aromatic hydrocarbon product (of benzene, toluene and xylene) and the cyclopentenone product. By using the renewable biomass derivative gamma-valerolactone as the raw material, the method has the advantage of milder reaction conditions, and the catalyst is simple to prepare and easy to recover and reuse.

A compound of formula

wherein Y represents a pyridyl group, or a phenyl group of formula

wherein R₃ represents a hydrogen atom, a CF₃ group or an alkoxy group, R₄ represents a hydrogen atom, an alkyl group, or a CF₃ group, R₅ represents a hydrogen atom, an alkyl group, a CF₃ group or an alkoxy group, and R₁ and R₂ are the substituents of a terminal alkene of formula

wherein R₁ represents an alkyl or alkylene group, a mono- or poly-cycloalkyl group, or a phenyl group that optionally includes one or several hetero-atoms of oxygen, nitrogen, phosphorous or sulfur; R₂ represents a hydrogen atom, an alkyl or alkylene group, a mono- or poly-cycloalkyl group, or a phenyl group that optionally includes one or several hetero-atoms of oxygen, nitrogen, phosphorous and sulfur. This compound is capable of releasing, upon an exposure to light, an active compound such as a perfume and can be advantageously used in the treatment of any surface in order to perfume it through the controlled release of a perfumed molecule.

The invention relates to a catalyst which using N-doped porous carbon as a carrier to support metal. The catalyst is composed of 0.1wt%-30wt% of metal particles and 70wt%-99.9wt% of bio-N-doped porous carbon carrier, and can be used for catalyzing aqueous phase hydrogenation of bio-furfural to highly selectively prepare furfural alcohol or cyclopentanone. The catalyst uses the raw materials which are renewable resources, wide in distribution, green and environmental, simple and easy to obtain, rich in resource, low in cost, free from inactivation when recycled for more than 50 times, and stable to air, water and heat. For example, in reaction of catalyzing the hydrogenation of the furfural to prepare the furfural alcohol, conversion rate of the supported metal catalyst can reach 100% and selectivity of the furfural alcohol is larger than 99% in an aqueous phase system.

Liquid crystalline compounds having a large negative Delta∈ low viscosity, a large K33/K11 value, a small Delta∈/Delta⊥ and mutually excellent solubility even at low temperature, compositions containing at least one of the compounds and liquid crystal display devices containing such a liquid crystal compositions are disclosed.

The present invention relates to a method for treprostinil diethanolamine synthesis. The present invention also relates to a novel intermediate used in the method for treprostinil diethanolamine synthesis. The novel intermediate is shown in the following formula (II):

wherein R1 and R2 are described in the description.

The invention provides a method for preparing cyclopentanone and/or cyclopentanol by furfural or furfuryl alcohol. The method includes the following steps of firstly, mixing furfural or furfuryl alcohol with solvent according to proportion; secondly, adding catalyst with hydrogenating function into the mixture in the first step; and thirdly, reacting in the reducing atmosphere to obtain cyclopentanone and/or cyclopentanol. The method for preparing cyclopentanone and/or cyclopentanol by furfural or furfural alcohol is high in yield of the cyclopentanone and/or cyclopentanol, and further, is simple in process, convenient to operate, mild in reaction conditions, no carbon deposition is caused during the whole reaction, the catalyst is low in cost and easy to obtain and can be reused without lowering activity.

The present invention provides processes, methods, and systems for converting biomass-derived feedstocks to liquid fuels and chemicals. The method generally includes the reaction of a hydrolysate from a biomass deconstruction process with hydrogen and a catalyst to produce a reaction product comprising one of more oxygenated compounds. The process also includes reacting the reaction product with a condensation catalyst to produce C₄₊ compounds useful as fuels and chemicals.

The invention discloses a synthetic process of 1-chloro-cyclopropanecarbonyl chloride, which belongs to the technical field of fine chemical processes. The process is implemented by taking alpha-acetyl-gamma-butyrolactone and sulfonyl chloride as raw materials through the steps of chlorinating, ring cleavage, cyclization, and re-chlorinating, so that a target product is obtained. The synthetic process is implemented by taking cheap industrial chemicals as raw materials and reaction reagents, and by using a single solvent system, a smooth process connection is achieved, so that the reaction yield is improved, the process operation is simplified, the cost of raw materials is reduced, and the cost of production is lowered.

Ketones, specifically Methyl ethyl ketone (“MEK”) and octanedione, may be formed from six carbon sugars. This process involves obtaining a quantity of a six carbon sugar and then reacting the sugar to form levulinic acid and formic acid. The levulinic acid and formic acid are then converted to an alkali metal levulinate and an alkali metal formate (such as, for example, sodium levulinate and sodium formate.) The alkali metal levulinate is placed in an anolyte along with hydrogen gas that is used in an electrolytic cell. The alkali metal levulinate within the anolyte is decarboxylated to form MEK radicals, wherein the MEK radicals react with hydrogen gas to form MEK, or MEK radicals react with each other to form octanedione. The alkali metal formate may also be decarboxylated in the cell, thereby forming hydrogen radicals that react with the MEK radicals to form MEK.

The invention belongs to the technical field of biomass conversion utilization, and concretely relates to a method for preparing cyclopentanone by taking biomass resource as a raw material. The method comprises taking furfural coming from biomass as the raw material, taking a hydrogen-containing gas as a reducing agent, and in the presence of a metal supported type catalyst, performing hydrogenation rearrangement reaction in a high-pressure reaction kettle or a fixed bed reactor, so as to obtain cyclopentanone in one step, wherein the carrier of the metal supported type catalyst is selected from Nb2O5, H-ZSM-5 molecular sieve, HY molecular sieve, Fe2O3, ZrO2, Al2O3, SiO2, CeO2, MgO, active carbon, and TiO2 in various crystal forms, the active composition is selected from Au, Pt, Ru, Rh, Pd, Ir, Ni and Cu, and the active composition load capacity is 0.1-5% of the catalyst. The method is mild in reaction technological conditions, and cheap and easily-available in raw materials, is capable of realizing quantitative conversion of furfural to cyclopentanone, and belongs to an environment-friendly green chemical technology.

Methods of converting cellulose or related biorenewable carbohydrate materials into high-value chemical compounds. The methods provide a means of converting low-cost materials such as cellulose and biomass into high yields of compounds such as ethylene glycol, propylene glycol, glycerin, methanol, hydroxyacetone, glycolaldehyde and dihydroxyacetone.

This invention relates to the 5-cis and 5-trans isomers of geranylgeranyl acetone, preferably such synthetic isomers, and pharmaceutical compositions containing such isomers. Other aspects of this invention relate to the use of geranylgeranyl acetone and its isomers in methods for inhibiting neural death, increasing neural activity, and increasing axon growth and cell viability. Geranylgeranyl acetone is a known anti-ulcer drug used commercially and in clinical situations. GGA has also been shown to exert cytoprotective effects on a variety of organs, such as the eye, brain, and heart.

A process for liquefying a cellulosic material to produce a liquefied product from cellulosic material is provided. Products obtained from such process and use of such products to prepare biofuels is also provided.

Efficient and recyclable heterogeneous nanocatalysts and methods of synthesizing and using the same are provided.

The invention discloses a preparation process of perfluoro-2-methyl-3-pentanone, belonging to the technical field of preparation methods of perfluoroketone compounds in the field of organofluorine chemistry. The perfluoro-2-methyl-3-pentanone is obtained by performing an epoxidation reaction and a catalytic isomerization reaction on perfluoro-2-methyl-pentene serving as a raw material in sequence. The preparation process comprises the following steps: I, in a continuous liquid phase epoxidation reaction, mixing a corresponding proportion of aprotic polar solvent into a sodium hypochlorite solution to promote the reaction, increase the raw material conversion ratio and increase the reaction rate at least by 2-3 percent, wherein the step is characterized by easiness and convenience in operation, low equipment requirement and high reaction equipment efficiency; II, performing a continuous gas phase catalytic reaction, wherein the application of a solvent is effectively avoided, the cost and environmental pollution are lowered, the problems of the need of separating the solvent from a product in post-treatment, difficulty in recycling and treating the solvent and a catalyst, and the like are solved, and the product can be refined and purified more easily. The preparation process has the advantages of high process automation degree, easiness and convenience in operation, high product purity and high reaction equipment efficiency, and is suitable for industrial application.

The present invention provides prodrugs of GABA analogs, pharmaceutical compositions of prodrugs of GABA analogs and methods for making prodrugs of GABA analogs. The present invention also provides methods for using prodrugs of GABA analogs and methods for using pharmaceutical compositions of prodrugs of GABA analogs for treating or preventing common diseases and/or disorders.

The invention discloses a preparation method of 1-(4-chlorophenyl)-2-cyclopropyl-1-acetone (I) and an intermediate thereof as well as the preparation method of the intermediate. The preparation method of 1-(4-chlorophenyl)-2-cyclopropyl-1-acetone (I) comprises the following steps of: carrying out Darzen condensation reaction on alpha-halo-p-chlorophenylacetate (II) and acetylcyclopropane (III) as raw materials in the presence of alkaline to prepare glycidic ester (IV); and carrying out basic hydrolysis on the obtained glycidic ester (IV) to be converted to a corresponding glycerate (V), and further carrying out decarboxylation reaction under acidic conditions to prepare 1-(4-chlorophenyl)-2-cyclopropyl-1-acetone (I) as a bactericide cyproconazole intermediate. The preparation method is simple in process, the three-step reaction can be realized through continuous operation or 'one-pot method'; and the product 1-(4-chlorophenyl)-2-cyclopropyl-1-acetone (I) is high in content and suitable for large-scale development.