1111 results about "Pentene" patented technology

Herbicidally active 3-phenylisoxazoline-5-carboxamides of cyclopentenylcarboxylic acid derivativesThe invention relates to 3-phenylisoxazoline-5-carboxamides of cyclopentenylcarboxylic acid derivatives of the general formula (I) and their agrochemically acceptable saltsand to their use in the crop protection sector.

The invention discloses production of terpenoids and a strain, and belongs to the technical field of bioengineering. The serratia marcescens engineering bacteria for producing the semi-terpenoids or monoterpenoids are constructed, and can be used for producing linalool, isoprene, isopentenol, 1, 3, 4-triterpenes and 1, 3, 4-triterpenes. The composition is prepared from 1, 8-cineole, alpha-pinene, pinene, gamma-terpinene, geraniol, (+)-limonene, (-)-limonene, myrcene, beta-ocimene, sabinene, (-)-alpha-bisabolol, (-)-alpha-bisabolol, longifolene, wallenenes, beta-elemene, farnesene, patchouli alcohol, acyclic terpene and alpha-santalene. In a 30L fermentation tank, the yield of linalool produced by the serratia engineering bacteria is 40.72 g.L <-1 >.

The invention relates to the technical field of biology, in particular to application of N-terminal truncated 8-isopentenyl transferase in production of 8-isopentene kaempferol. The invention provides the N-terminal truncated 8-isopentenyl transferase, and the N-terminal truncated 8-isopentenyl transferase can be used for carrying out isopentenylation on kaempferol to generate 8-isopentene kaempferol. Specifically, the saccharomyces cerevisiae is used as a chassis, under the condition that kaempferol is exogenously added, through overexpression of 8-isopentenyl transferase, biosynthesis of 8-isopentenyl kaempferol in the saccharomyces cerevisiae is realized, and meanwhile, a foundation is laid for subsequent biosynthesis of icaritin. The invention provides a novel reference scheme for biosynthesis of flavonoid compounds.

The invention belongs to the field of fluorine-containing fine organic chemical synthesis, and particularly relates to a method for continuously and cleanly producing perfluoroolefin epoxide by using hydrogen peroxide. The invention relates to a method for continuously and cleanly producing perfluoroolefin epoxide by using hydrogen peroxide, which comprises the following steps of: reacting perfluoro-2-methyl-2-pentene serving as a raw material in the presence of a polar solvent and hydrogen peroxide serving as an oxidant under the action of a catalyst to obtain perfluoro-2-methyl-2, 3-epoxypentane. The method has the beneficial effects that the micro-reactor is used, and the oxidizing agent, the catalyst, the cocatalyst and the polar solvent are continuously introduced into the pipeline of the micro-reactor, so that the synthesis from the hexafluoropropylene dimer to the epoxy compound is completed in a short time.

The invention discloses a polycyclic polyisopentenyl phloroglucinol compound as well as a preparation method and application thereof, and belongs to the technical field of biological medicines. The method comprises the following steps: by taking a dry overground part of hypericum monogynum as a raw material, performing percolation extraction and concentration to obtain an extract, suspending the extract in water to obtain a suspension, and performing extraction and concentration to obtain a petroleum ether part extract; the extract is taken and subjected to separation through a positive and negative phase silica gel column, MCI medium-pressure column chromatography and Sephadex LH-20 gel column chromatography and purification through high performance liquid chromatography, the polycyclic polyisopentenyl phloroglucinol compound is prepared, and the structure and configuration of the compound are determined by means of a spectrum analysis technology, quantum chemistry calculation, X-ray single crystal diffraction and the like. The compound can inhibit TNF-alpha protein to play an immunosuppressive role, and can be used as an immunosuppressive drug.

The invention belongs to the technical field of polyurethane waterproof coatings, and particularly relates to a single-component fluorine-free high-hydrophobicity polyurethane waterproof coating and a preparation method thereof, and the single-component fluorine-free high-hydrophobicity polyurethane waterproof coating comprises the following raw materials by weight: 60-80 parts of composite polyether polyol; 20 to 40 parts of silane modified polyether polyol; 11 to 17 parts of diisocyanate; 2-5 parts of a chain extender; 50 to 70 parts of a plasticizer; 50 to 70 parts of filler; 0.15 to 0.2 part of a catalyst; and 3-5 parts of an auxiliary agent. A polyoxypentene ether chain segment, a castor oil-based structure and a silane group are introduced into the molecular structure of the waterproof coating through chemical modification, the intrinsic hydrophobic and mechanical properties of the material are improved, the migration defect caused by addition of a hydrophobic agent and silicone oil in a traditional preparation method is overcome, and the invention further provides a preparation method of the waterproof coating.

The invention relates to the technical field of bioengineering, and discloses a genetically engineered bacterium and a method for producing icaritin through whole-cell catalysis. By constructing double plasmids, choline kinase, isopentenyl phosphokinase, flavonoid 3-hydroxylase, flavonol synthase, isopentenyl transferase and oxymethyltransferase are simultaneously overexpressed in escherichia coli, so that a genetically engineered bacterium is constructed, and the engineering bacterium is used as a whole-cell catalyst to prepare a whole-cell engineering bacterium. The naringenin and the 3-methyl-2-butene-1-ol are used as substrates to be converted into the icaritin in a whole-cell catalysis mode, only one-step reaction is needed, the method is simple, rapid and high in efficiency, other chemical substances do not need to be additionally added in the conversion process, the cost is reduced, pollution to the environment is relieved, and the method is suitable for industrial production. And the biological production from low-price naringenin to high-added-value icaritin is realized.

The invention discloses a preparation method of an optical OCA (Optical Clear Adhesive) and application of the optical OCA in a mobile phone folding screen, and relates to the technical field of optical cement, the optical OCA is prepared from the following raw materials in parts by weight: 50 parts of acrylate prepolymers, 2-4 parts of 3-allyl-2-mercapto-3H-quinazoline-4-ketone, 1-3 parts of diallyl disulfide, 1-3 parts of 3-[N, N-dimethyl formamide], 1-3 parts of 2, 3, 5-trimethyl-1, 3-pentanediol monoisobutyronitrile, 1-3 parts of 2, 3, 5-trimethyl-1, 3, 5-trimethyl-1, 3, 5-trimethyl-1, 3 The preparation method comprises the following steps: adding 3-5 parts of N, N-dimethyl-[2-(2-methylpropane-2-enoyloxy) ethyl] ammonium] propane-1-sulfonic acid inner salt, 1-3 parts of allyl succinimido carbonate, 2-4 parts of dicyclopentene methacrylate, 1-3 parts of 1, 3, 5-triacryloyl hexahydro-1, 3, 5-trimethyl-1, 3, 5-trimethyl-1, 3, 5-trimethyl-1, 3, 5-trimethyl-1, 3, 5-trimethyl-1, 3, 5-trimethyl-1, 3, 5-trimethyl-1, 3, 5- The invention relates to a graphene quantum dot photoinitiator which is prepared from the following components in parts by weight: 1-3 parts of 1, 3, 5-triazine, 0.8-1.2 parts of a photoinitiator, 1-3 parts of an aziridine cross-linking agent, 1-3 parts of graphene quantum dots, 0.8-1.2 parts of a coupling agent and 40-50 parts of a diluent. The optical OCA adhesive is high in light transmittance and bonding strength, good in weather resistance and excellent in folding resistance.

The invention discloses a continuous method for preparing 4-methyl-1-pentene through propylene dimerization and the obtained 4-methyl-1-pentene. The continuous method for preparing the 4-methyl-1-pentene through propylene dimerization comprises the steps that components containing propylene and a catalyst react in a reactor in the presence of a solvent, the product obtained after the reaction is separated, and then the 4-methyl-1-pentene is obtained, and the reactor comprises a first solid-liquid reaction kettle and a second solid-liquid reaction kettle. According to the invention, the continuous propylene dimerization reaction is realized, the blank of the domestic production technology for preparing 4-methyl-1-pentene by propylene dimerization is hopefully filled, sufficient raw materials are provided for the production of PMP, the current situation that the PMP completely depends on import in China is broken through, and the method has great significance.

The invention discloses a synthetic method of glabridin with optical purity, which comprises the following steps: by taking (R)-3-acetoxyl-2-(2, 4-dimethoxyphenyl) propanol and 2-isopentenyl resorcinol as raw materials, carrying out Mitsunobu reaction to obtain a key intermediate compound I, then carrying out hydrolysis and iodination to obtain an intermediate compound II, and then carrying out cyclization to obtain the glabridin with optical purity. Reducing and removing a protecting group to obtain glabridin. By introducing the isopentene side chain, the reaction activity of an olefin functional group is reserved, a key site is provided for subsequent cyclization conversion, the precise spatial configuration of the product is ensured, and finally glabridin with optical purity is prepared. The method is short in route, low in cost, mild in reaction condition and suitable for industrial production.

The invention relates to the technical field of all-solid-state batteries, in particular to air-stable argyrodite type sulfide electrolyte, a preparation method thereof and an all-solid-state battery. The air-stable argyrodite type sulfide electrolyte provided by the invention comprises a sulfide solid electrolyte and a protective layer formed by self-assembly of organic molecules on the surface of the sulfide solid electrolyte, wherein the sulfide solid electrolyte is argyrodite type sulfide solid electrolyte, the general formula of the sulfide solid electrolyte is Li < 7-a > PS < 6-a > X , X is halogen, and a is more than 0 and less than 2; the organic molecule is at least one of 1-methoxyhexane, 2-heptanone, 3-chloropropanol, 4-chlorobenzyl mercaptan, n-amylamine, 5-chloromethyl-1, 3-benzodioxole, chlorophenylmethane and ethylbenzene, and the organic molecule is at least one of 1-methoxyhexane, 2-heptanone, 3-chloropropanol, 4-chlorobenzyl mercaptan, n-amylamine, 5-chloromethyl-1, 3-benzodioxole, chlorophenylmethane and ethylbenzene. According to the air-stable argyrodite type sulfide electrolyte provided by the invention, the stability of the sulfide electrolyte to water can be enhanced, and the ionic conductivity of the sulfide electrolyte can be ensured.

To provide a multi-layer biaxially oriented film that is resistant to tearing and the like even when stretched at high ratios, and that exhibits excellent heat resistance, particularly heat seal resistance (low shrinkage during heat sealing).SOLUTION: A multi-layer biaxially oriented film comprises an A layer and a B layer, wherein the A layer comprises: a resin composition comprising 75-99 mass% of a polymer satisfying (I) to (II); and 1-25 mass% of a copolymer satisfying (III) to (IV). (I): A content of a constituent unit derived from 4-methyl-1-pentene is 90.0-100 mol%, and a content of a constituent unit derived from a C3-20 α-olefin other than 4-methyl-1-pentene is 0.0 to 10.0 mol%. (II): A melting point is 200-250°C. (III): A content of a constituent unit derived from 4-methyl-1-pentene is 65.0-96.0 mol%, and a content of a constituent unit derived from a C8-20 α-olefin is 4.0 to 35.0 mol%. (IV): A melting point is not observed or is 100 to 199°C.SELECTED DRAWING: None

The preparation method comprises the following steps: crushing epimedium sagittatum to prepare paste, suspending with water, extracting with petroleum ether, dichloromethane, ethyl acetate and n-butyl alcohol respectively to obtain extractum of each part, carrying out gradient elution separation by using silica gel column chromatography, and concentrating to obtain the isopentenyl flavone compound extracted from epimedium sagittatum, thereby obtaining the isopentenyl flavone compound extracted from epimedium sagittatum. Combining the similar parts according to a thin layer chromatography (TLC) color development result to obtain a plurality of polar segments; carrying out chromatography and gradient elution on the target polar section to obtain a plurality of components, and then combining the similar components through thin-layer chromatography (TLC) dot plate absorption to obtain a plurality of sub-components; a target component is eluted and purified, fractions with different retention times are collected and dried, and two compounds are respectively obtained, have a remarkable inhibition effect on the cell viability of human breast cancer cells MCF-7, have anti-breast cancer activity, can be applied to preparation of drugs for treating breast cancer, and have huge social and economic benefits.

The invention discloses a perovskite solar cell based on buried interface modification and a preparation method and application thereof. The invention relates to an application of 2-(acrylamide) benzoic acid and / or 2-(4-pentenoylamido) benzoic acid in a trans-perovskite solar cell buried interface modifier. According to the invention, 2-(acrylamide) benzoic acid and / or 2-(4-pentenylamido) benzoic acid are / is used as a buried interface modifier, such molecules take benzoic acid as an anchoring group, and through the synergistic effect among carboxyl, amido and carbon-carbon double bonds, the defects at the thin film grain boundary of the hole transport layer and the perovskite layer are reduced; according to the invention, the NiOX thin film is introduced into the small molecules, and the alkyl chain is further introduced into the small molecules and can effectively fill small recesses and holes in the NiOX thin film, so that the flatness of the NiOX thin film is improved, a compact and compact modification layer is formed, the morphology of the perovskite layer thin film is further regulated and controlled, and the photoelectric conversion efficiency of the perovskite solar cell is improved.

Methods for treating immune thrombocytopenia comprising administering at least one compound chosen from (R)-2-[3-[4-amino-3-(2-fluoro-4-phenoxy-phenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl]-4-methyl-4-[4-(oxetan-3-yl)piperazin-1-yl]pent-2-enenitrile (rilzabrutinib) and pharmaceutically acceptable salts thereof are disclosed.

The invention discloses a modified graphene antistatic fiber and a preparation method thereof, and relates to the technical field of chemical fibers. When the modified graphene antistatic fiber is prepared, polyethylene glycol terephthalate, an ultraviolet absorption monomer and dimethyl (vinyl) silane react to prepare modified polyester; the preparation method comprises the following steps: polymerizing thiophene, hydantoin thiophene and 3-vinyl thiophene, and coating the phase change microcapsule with the polymerized thiophene, hydantoin thiophene and 3-vinyl thiophene to prepare a pre-modified phase change microcapsule; reacting the pre-modified phase change microcapsule with sodium hypochlorite to obtain a modified phase change microcapsule; the pre-modified graphene and 5-chloro-1-pentene are subjected to a reaction, and modified graphene is prepared; preparing a spinning solution from the modified polyester, the modified phase change microcapsules, the modified graphene, chloroplatinic acid and N, N-dimethylformamide, and performing wet spinning to obtain the modified graphene antistatic fiber. The modified graphene antistatic fiber prepared by the invention has excellent anti-aging, antibacterial, flame-retardant, antistatic, warm-keeping and mechanical properties.

To provide a laminate which has excellent printability, heat sealability and heat resistance and hardly causes wrinkles on appearance after heat sealing.SOLUTION: There is provided a laminate which has a layer (I) containing a thermoplastic resin, a resin layer (II) containing a 4-methyl-1-pentene-based polymer (A) satisfying following requirements (A) to (c) and a layer (III) containing a thermoplastic resin in a thickness direction in this order: (a) a melting point (Tm) measured by a differential scanning calorimeter (DSC) is 180 to 220°C, (b) an endothermic end temperature (TmE) in a melting (endothermic) curve measured by DSC is 230°C or less and (c) an exothermic start temperature (TcS) in the crystallization (exothermic) curve measured by DSC is 210°C or less.SELECTED DRAWING: None

The invention provides a method for preparing isopentenol from 3-methyl-1-butene, which comprises the following steps: oxidizing 3-methyl-1-butene to obtain a 2-isopropyl ethylene oxide intermediate, and then isomerizing the intermediate to obtain the isopentenol. The synthesis route is novel, the cheap refined C5 byproduct 3-methyl-1-butene is used as a starting raw material, the isopentenol is simply and efficiently prepared through two-step reaction of epoxidation, isomerization and the like, and an economical and feasible route is provided for preparation of the product; and secondly, in the isomerization reaction in the second step, lithium phosphate treated by sodium alcoholate or potassium alcoholate is used as a catalyst, so that the isomerization reaction of the epoxy intermediate is efficiently realized, and the isopentenol is conveniently and quickly prepared. # imgabs0 #

The present invention relates generally to novel mixtures of (2E)-3-(1, 3-benzodioxol-5-yl)-N-phenyl-N-(tetrahydro-3-furyl)-2-acrylamide and to the use thereof.

The invention discloses Klebsiella and application thereof, and belongs to the technical field of microorganisms. According to the invention, firstly, a strain LLMJ-DNXJ-01 with high yield of tannase is screened from wine-making yeast, the identification result shows that the strain belongs to klebsiella, then the tannase activity of the strain is investigated, and the result shows that the enzyme activity reaches 8.8 + / -0.02 U / mL. In addition, the invention also investigates the application of the strain in degrading sorghum tannin, the sorghum tannin degradation rate reaches 34.95%, and isoamyl alcohol, isopentenol, caryophyllene, phenethyl alcohol, 4-vinyl guaiacol and other volatile aroma substances with Daqu characteristics can be generated through fermentation. Therefore, by integrating the tannase production capability of the strain LLMJ-DNXJ-01 and the sorghum tannin degradation and fermentation aroma production capability, the strain has relatively good development potential in the aspects of manufacturing of reinforced yeast for making hard liquor and quality improvement and aroma enhancement of white spirit.

The invention provides a method for biosynthesizing menadione by using yarrowia lipolytica. The method is realized by constructing recombinant yarrowia lipolytica, and the construction method of the recombinant yarrowia lipolytica for synthesizing menadione comprises the following steps: intensively expressing a mevalonic acid pathway in the yarrowia lipolytica, and synthesizing menadione by introducing a synthesis pathway of heterologous geranyl and geranyl pyrophosphate. A sufficient isoprene side chain donor is provided for biosynthesis of menadione; on the basis, an aromatic isopentenyl transferase coding gene which is optimized by codons and has menadione substrate specificity is over-expressed in yarrowia lipolytica. The construction method of the yarrowia lipolytica for biosynthesis of menadione provided by the invention is simple to operate, the constructed yarrowia lipolytica can obtain a menadione product with relatively high concentration by taking commercially available menadione as a substrate, the biosynthesis steps are relatively short, and the yarrowia lipolytica has relatively high production and application values.

A technology for preparing glutaraldehyde through cyclopentene oxidation belongs to the technical field of organic synthesis, glutaraldehyde is prepared through cyclopentene oxidation by adopting a photocatalysis-electrocatalysis synergistic catalyst g-C3N4 / TiO2 (at) Au-Co / N-G. The catalyst is of a unique core-shell structure, is stable in property, promotes an oxygen reduction reaction in a catalysis technology, and has good catalytic activity. The conversion rate of cyclopentene and the selectivity of glutaraldehyde are remarkably improved, and the effect is remarkable.

The invention relates to the technical field of organic synthesis, in particular to a method and device for preparing 4-methyl-1-pentene, and the method comprises the following steps: (1) pretreating a raw material containing propylene and an inert substance, and carrying out heat exchange on the obtained refined raw material to obtain a heat-exchanged raw material; (2) carrying out dimerization reaction on the raw material subjected to heat exchange and a catalyst in the presence of inert gas, wherein the obtained reaction product is divided into a part of reaction product and a residual part of reaction product; (3) cooling the part of the reaction product as a heat exchange medium, and carrying out heat exchange with the refined raw material to obtain a heat-exchanged product; (4) separating a mixed material of the rest reaction product and the product after heat exchange to obtain a light component and a heavy component; and carrying out rectification on the heavy component to obtain the 4-methyl-1-pentene. According to the method, by controlling the reaction temperature rise, the stable reaction temperature and the uniform reaction process are ensured, and the raw material conversion rate and the product selectivity are further improved.

Methods for treating patients with moderate-to-severe asthma comprising administering a therapeutically effective amount of at least one compound chosen from (R)-2-[3-[4-amino-3-(2-fluoro-4-phenoxy-phenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl]-4-methyl-4-[4-(oxetan-3-yl)piperazin-1-yl]pent-2-enenitrile (rilzabrutinib) and pharmaceutically acceptable salts thereof are disclosed.

The invention belongs to the technical field of organic synthesis, and relates to a preparation method of 5, 5-dimethyl-4, 5-dihydroisoxazole. The method comprises the following steps: (1) reacting isopentenal with an oximation agent to obtain a reaction solution containing isopentenal oxime; (2) dropwise adding the reaction liquid into a mixture containing isopentenal and an acid catalyst for reaction to obtain a product; or when the reaction liquid contains water, performing phase splitting on the reaction liquid to obtain an organic phase, and dropwise adding the organic phase into a mixture containing the isopentenal and the acid catalyst for reaction to obtain a product. The method does not produce ketone by-products, and is good in atom economy, high in reaction yield, good in technological process continuity, low in cost, few in materials, simple to operate, mild in reaction condition, low in requirements on production equipment and suitable for large-scale industrial production.

The invention relates to the technical field of chemical engineering, and discloses a catalyst, a preparation method and application of the catalyst in preparation of isopentenal. According to the catalyst for catalyzing isomerization rearrangement of 2-methyl-3-butyne-2-alcohol to prepare isopentenal, provided by the invention, the lanthanide metal oxide is utilized to modify the supported vanadium catalyst, so that the selectivity of the catalyst can be improved, and the yield of isopentenal is increased. According to the synthesis process of the isopentenal, 2-methyl-3-butene-2-alcohol can be isomerized and rearranged into the isopentenal by adopting a reactive distillation mode without using a toxic solvent, efficient and continuous production of the isopentenal is realized, meanwhile, under the catalytic action of the catalyst, the raw material can be converted into the isopentenal with high selectivity, the yield of the isopentenal is increased, and the yield of the isopentenal is increased. And under proper process conditions, hydrogen ions can be provided in the presence of a proper amount of water, so that the raw materials are promoted to be subjected to isomerization rearrangement reaction quickly, the surface temperature of the catalyst is reduced, and the carbon deposition phenomenon of the catalyst is relieved to a certain extent.

The invention relates to a crystal form of a compound (S)-1-((2 ', 6-bis (difluoromethyl)-[2, 4'-bipyridyl]-5-yl) oxy)-2, 4-dimethyl pent-4-ene-2-amine as shown in a formula (I) and a salt thereof, a preparation method of the crystal form, and application of the crystal form in a pharmaceutical composition and medicine of the compound (S)-1-((2 ', 6-bis (difluoromethyl)-[2, 4'-bipyridyl]-5-yl) oxy)-2, 4-dimethyl pent-4-ene-2-amine and the salt thereof. # imgabs0 #

The preparation method of the isopentenyl flavone enantiomer compound comprises the following steps: crushing epimedium sagittatum to prepare paste, suspending with water, respectively extracting with petroleum ether, dichloromethane, ethyl acetate and n-butyl alcohol to obtain extractum of each part, carrying out gradient elution separation by using silica gel column chromatography, and concentrating to obtain the isopentenyl flavone enantiomer compound, namely the isopentenyl flavone enantiomer compound. Combining the similar parts according to a thin layer chromatography (TLC) color development result to obtain a plurality of polar segments; carrying out chromatography and gradient elution on the target polar section to obtain a plurality of components, and then combining the similar components through thin-layer chromatography (TLC) dot plate absorption to obtain a plurality of sub-components; a target component is eluted and purified, fractions with different retention times are collected and dried, and four compounds are obtained respectively, have a remarkable inhibition effect on the cell viability of human breast cancer cells MCF-7, have anti-breast cancer activity, can be applied to preparation of drugs for treating breast cancer, and have huge social and economic benefits.

The invention relates to a polycarboxylic acid water reducer and a preparation method thereof, and the water reducer is prepared from the following raw materials: 45 to 55 percent of isopentenyl polyoxyethylene ether, 28 to 35 percent of acrylic acid, 1.5 to 2.5 percent of modifier, 0.3 to 0.5 percent of ammonium persulfate, 0.03 to 0.06 percent of ascorbic acid, 5 to 8 percent of hydroxyethyl methylacrylate, 0.15 to 0.25 percent of 2, 4-diphenyl-4-methyl-1-pentene and the balance of water. The modifier is prepared from the following raw materials: 1, 5-dichloronaphthalene, p-nitrostyrene, dimethyl sulfate, ceric ammonium nitrate and tetramethylpiperidine oxide. The polycarboxylate superplasticizer has excellent neat paste fluidity and fluidity retention capability, has low 1h time-dependent variable slump which is below 18mm and optimally 10mm when applied to concrete, has a water-reducing rate of more than 40% and a gas content of less than 3.8%, and also has more advantages in compressive strength ratio.

The invention relates to the technical field of propylene dimerization, in particular to a method and device for preparing 4-methyl-1-pentene through propylene dimerization, and the method comprises the following steps: (1) dehydrating and deoxidizing a raw material containing propylene, a coking inhibitor and a diluent to obtain a treated raw material; (2) contacting the treated raw material with a catalyst, carrying out dimerization reaction to obtain a reaction material, carrying out heat treatment on part of the reaction material, returning, and carrying out the dimerization reaction; (3) carrying out rectification separation on the rest reaction material to obtain a light component, 4-methyl-1-pentene and a heavy component; wherein the total temperature rise delta T of the dimerization reaction is regulated and controlled through the mass ratio of the diluent to the propylene in the raw materials and the recycle ratio of the reaction materials, and the recycle ratio of the reaction materials is the mass ratio of the part of the reaction materials to the propylene in the raw materials. According to the method, the selectivity of the 4-methyl-1-pentene is effectively improved.