282 results about "Pentane" patented technology

This invention provides an environmentally friendly expandable polystyrene bead and its preparation process, belonging to the field of foaming material technology. The preparation process includes the following steps: S1, injecting 65.28g of deionized water into a reaction vessel, stirring, adding 0.13g of dispersant and 0.16g of composite stabilizer, dispersing for 20min, then adding 31.95g of styrene monomer and 0.3g of composite initiator, followed by the addition of pentane and SiO2 micelle composite to obtain a base solution; wherein the mass ratio of pentane to SiO2 micelle composite is 1:(0.2-0.3); the mass of pentane is 3.1%-3.2% of the mass of the base solution; S2, subjecting the base solution to stepwise heating at 86℃-140℃ with stirring, then stopping heating, continuing stirring, and allowing it to cool naturally to 40℃, then stopping stirring, with a total reaction time of 8.5-9.5h to obtain the reaction product; S3, discharging the material, washing the reaction product with warm water, filtering, and obtaining the environmentally friendly expandable polystyrene beads. This invention improves the average particle size of expandable polystyrene beads while reducing fine powder.

The invention belongs to the technical field of drug synthesis, and particularly relates to an adamantane derivative as well as a synthesis method and application thereof. The adamantane derivative comprises an intermediate structural formula I, an intermediate structural formula II and an intermediate structural formula III, and the structural general formula is as follows: Linker is substituted or unsubstituted C6-C10 aroyl, R1 is hydrogen or C1-C6 alkyl, R2 is hydrogen, C1-C6 alkyl or a nitrogen-containing or nitrogen-free structural fragment, or the integral structure of R1R2 is N-substituted heterocyclic pentyl or heterocyclic cyclohexyl. According to the adamantane derivative provided by the invention, an adamantane structure is combined with part of groups of OAB-14, and a parent nucleus structure is changed, so that the drug activity is improved. The invention also provides a synthesis method of the compound, the obtained compound is screened through cell viability research, and the compound has a potential synergistic effect in the aspects of preventing influenza and treating Alzheimer's disease.

The invention belongs to the technical field of organic synthesis, and provides a preparation method of a cationic lipid compound, which comprises the following steps: (1) reacting 1, 5-dihalopentane, 2-tert-butyl glycolate and alkali to obtain a product G; (2) hydrolyzing the product G under an acidic condition to obtain a product H; (3) carrying out esterification reaction on the product H, the raw material C, 4-dimethylaminopyridine and a condensing agent in dichloromethane to obtain a product J; and (4) carrying out amination reaction on the product J, the raw material L and alkali in acetonitrile to obtain the cationic lipid compound. Compared with the prior art, the method has the relatively remarkable advantages that when the first part of halogenated long-chain alkyl ester H is synthesized by the method, 1, 5-dihalopentane and 2-tert-butyl glycolate are used as raw materials, the halogenated long-chain alkyl ester J is synthesized by a simple method, the product is obtained at a higher yield in synthesis, and the method is suitable for kilogram-level production. The route synthesis only comprises four steps of chemical reactions, and is suitable for industrial production.

The invention belongs to the technical field of medicine synthesis, and particularly relates to a memantine derivative and a synthesis method and application thereof. The memantine derivative comprises an intermediate structural formula I, an intermediate structural formula II, an intermediate structural formula III and a structural general formula, Linker is substituted or unsubstituted C6-C10 aroyl, R1 is hydrogen or C1-C6 alkyl, R2 is hydrogen, C1-C6 alkyl or a nitrogen-containing or nitrogen-free structural fragment, or the integral structure of R1 and R2 is N-substituted heterocyclic pentyl or heterocyclic cyclohexyl. According to the memantine derivative provided by the invention, a memantine group is combined with an OAB-14 partial structure to change a parent nucleus structure, so that the drug activity is improved. The invention also provides a synthesis method of the compound, and the obtained compound is used for treating Alzheimer's disease and Parkinson's disease.

The application belongs to the field of catalyst synthesis, and relates to a polymer polynuclear boron organic catalyst, a preparation method and application thereof, the preparation method of the catalyst comprises the following steps: adding tetrahydrofuran into a catalyst precursor, then adding a borohydride reagent drop by drop, heating the reaction mixture at 25-80 DEG C for 22-26 h, vacuum concentrating the reaction mixture to obtain a crude product, purifying the crude product by washing with pentane for 2-5 times, and vacuum drying the product at normal temperature for 10-14 h to obtain the catalyst; the catalyst precursor and a preparation method thereof are also provided; the polymer polynuclear boron organic catalyst provided by the application has the advantages of high activity, simple preparation method and low cost, and the catalyst can control the polymer substrate type and the polymer type by adjusting the reaction conditions, the catalytic system and the substrate, and can efficiently prepare polymers such as polyether, polyester and polycarbonate due to the synergistic effect of the polynuclear boron center, so that the types of the organic catalyst and the polymer are greatly expanded.

The invention relates to the technical field of organic synthesis, in particular to a method for synthesizing cyclopentane compounds through [3 + 2] cycloaddition reaction of aryl cyclopropane and olefin under the synergistic catalysis of bromide ions / visible light. The method comprises the following steps: in a nitrogen atmosphere, sequentially adding aryl cyclopropane, a benzyl malononitrile derivative, pyridine tribromide and a photocatalyst into a reaction solvent to obtain a mixture, stirring the mixture at the temperature of 40 DEG C under the irradiation of a 12W blue light LED lamp until the reaction is complete, and performing concentration and column chromatography purification to obtain the cyclopentane compound. The method has the advantages of mild reaction conditions, simple operation, simple and easily available raw materials and low cost.

The invention discloses a zinc transition metal coordination polymer and a preparation method and application thereof, and relates to the technical field of metal-organic framework material photocatalysts, the chemical formula of the zinc transition metal coordination polymer is [Zn2 (L) 2 (byp)] n, and the zinc transition metal coordination polymer is prepared from 3, 3 '-(1, 2-phenyl dimethylene diether) dibenzoic acid ligand (H2L), 1, 2, 3, 4-tetramethyl-1, 3, 4-tetramethyl-1, 3, 4-tetramethyl-1, 3, 4-tetramethyl-1, 3, 4-tetramethyl-1, 3, 4-tetramethyl-1, 3, 4-tetramethyl-1, 3, 4-tetramethyl-1 The polymer is prepared by co-dissolving 1, 5-bis (2-methyl-1-imidazolyl) pentane ligand (pyp) and Zn (Ac) 2.6 H2O in an aqueous solution, and the polymer has a wide prospect in application of photocatalytic degradation of antibiotics as a photocatalyst.

The utility model discloses a pentane gasification protection device and belongs to the technical field of pentane gasification. The protection device comprises a mounting table, a gasification tank arranged on one side of the mounting table, a detector fixedly mounted on the gasification tank, a control panel fixedly mounted on the mounting table, a gas conveying mechanism fixedly mounted on the mounting table and used for conveying gas to the gasification tank, and a liquid conveying mechanism fixedly mounted on the mounting table and used for conveying liquid to the gasification tank, the air conveying structure comprises a fan fixedly mounted on the mounting table and an air conveying pipe fixedly mounted on the fan; through cooperative use of the devices, the detector can send an abnormal signal to the control panel after detecting that the working environment is abnormal, and the control panel can quickly close the fan and interrupt gas supply in the gasification tank, so that the problem that manual treatment is not timely is avoided, possible loss is reduced to the minimum, and the safety of personnel and equipment is guaranteed.

This invention discloses a method for the efficient conversion of isoparaffins, comprising the following steps: contacting a raw material containing isoparaffins and hydrogen with a catalyst in a reactor, reacting to obtain a product containing small molecule alkanes; wherein the isoparaffins are selected from at least one of isobutane, isopentane, neopentane, isohexane, and 3-methylpentane; wherein the small molecule alkanes are selected from at least one of ethane, propane, and n-butane; the catalyst is obtained by the following steps: mixing a metal acidic functional component, a metal basic functional component, a matrix precursor, a phosphorus auxiliary component precursor, a molding aid, and water, kneading, molding, and vacuum drying to obtain the catalyst.

The invention provides a production method of high-purity cyclopentene, and belongs to the technical field of olefin production. According to the method, a crude cyclopentene raw material rich in cyclopentene, cyclopentane and 1, 2-pentadiene is mixed with hydrogen, the mixture is introduced into an adiabatic bubbling bed reactor for a selective hydrogenation reaction, and a catalyst is modified Pd / Al2O3. After hydrogenation reaction liquid is subjected to light component removal and refining, a high-purity cyclopentene product with the content of 99.9% or above and the content of 1, 2-pentadiene being 10 ppm or below is obtained, and the monomer requirement for producing cyclopentene rubber is met.

The application discloses a method for producing ethylene raw material. The method comprises the following steps: mixing hydrocracking light naphtha and hydrogen into a first hydroconversion reaction zone to react, and then the reaction effluent enters a separation system to obtain hydrogen-rich gas and a first hydroconversion product; the first hydroconversion product is separated to obtain ethane, propane, isobutane, isopentane and n-pentane; the isobutane is mixed with hydrogen into a second hydroconversion reaction zone, and the reaction effluent is separated to obtain n-butane; the second hydroconversion reaction zone is filled with a hydroconversion catalyst containing ZSM-35 molecular sieve; and the isopentane is recycled to the inlet of the first hydroconversion reaction zone. The first hydroconversion reaction zone is filled with a hydroconversion catalyst containing mordenite, and at least two catalyst beds are filled; and the active metal content of the hydroconversion catalyst decreases in turn along the flow direction. The method can effectively improve the proportion of normal alkanes in the product and improve the quality of the ethylene raw material.

Ethylene, alpha olefins, and other olefinically unsaturated monomers may be polymerized under fluidized bed polymerization reaction conditions in the presence of a Ziegler-Natta catalyst. A recycle stream featuring an induced condensing agent (ICA) comprising isobutane may increase catalyst productivity while maintaining quality of the polymer product, particularly when the recycle stream is delivered to a reactor containing the fluidized bed under conditions suitable to form a condensed or super-condensed mode in the recycle stream. The recycle stream may comprise unreacted olefinic monomers, and isobutane or a mixture of isobutane and isopentane.

The present application relates to an electrolyte composition for a lithium secondary battery and a lithium secondary battery comprising the same, the electrolyte composition comprising a lithium salt and an organic solvent. The organic solvent includes a first ether solvent (R-O-R ') having a fluorinated alkyl group, and a second ether solvent. The first ether solvent may be 5-ethoxy-1, 1, 2, 2, 3, 3, 4, 4-octafluoropentane, 1, 1, 2, 2, 3, 3, 4, 4-octafluoro-5-methoxypentane, or a mixture thereof, and the second ether solvent may be selected from the group consisting of dimethoxyethane, diethyl ether, and similar ethers. The lithium salt includes a compound such as LiTFSI, LiFSI, or LiPF6. The first ether solvent accounts for 30% to 90% by volume of the electrolyte, wherein the concentration of the lithium salt ranges from 0.1 M to 3.0 M. The electrolyte composition enhances battery stability and makes it suitable for use in lithium secondary batteries and lithium metal secondary batteries.

The invention provides a crystal form VI of an acrylamide compound, and the acrylamide compound is (S)-N-(5-((6-(2-(7, 7-dimethyl-1-oxo-1, 3, 4, 6, 7, 8-hexahydro-2H-cyclopentane [4, 5] pyrrolo [1, 2-a] pyrazine-2-yl)-3-(hydroxymethyl) pyridine-4-yl)-4-methyl-3-oxo-3, 3, 4-triazolo [1, 2-a] pyrazine-2-yl)-3-(hydroxymethyl) pyridine-4-yl)-4-methyl-3-oxo-3, 3, 4-triazolo [1, 2-a] pyrazine-2-yl)-3-(2, 3, 4-triazolo [1, 2-a] pyrazine-2-yl)-4- The crystal form VI is a 2-(2, 4-dihydropyrazine-2-yl) amino)-2-(2-methyl-4-(tetrahydro-2H-pyran-4-yl) piperazine-1-yl) 5phenyl) acrylamide compound, and an X-ray powder diffraction pattern of the crystal form VI comprises diffraction peaks with the following 2 theta angle values: 8-3 + / -0.2 degrees, 13.2 + / -0.2 degrees and 18.9 + / -0.2 degrees. The crystal form VI has the advantages of good stability and low hygroscopicity, and is suitable for industrial production of bulk drugs and development of preparation prescriptions.

This invention discloses a high-strength and tough PET foam sheet and its preparation method, belonging to the field of foam material technology. It comprises the following raw materials in parts by weight: 100 parts food-grade PET resin, 3-7 parts melt reinforcing agent, 3-5 parts crystallization toughening agent, 1-3 parts in-situ fiber-forming reinforcing agent, 1-5 parts compatibility dispersant, and 8-10 parts cyclopentane. The preparation method includes: S1, mixing dried food-grade PET resin with melt reinforcing agent, crystallization toughening agent, in-situ fiber-forming reinforcing agent, and compatibility dispersant to obtain a premix; S2, melting and plasticizing the premix, injecting liquid cyclopentane for blending, and then extruding to a normal pressure environment to obtain a foam sheet blank; S3, cooling and shaping the foam sheet blank, drawing, trimming, and winding to obtain a high-strength and tough PET foam sheet. The foam sheet obtained by this invention has fine and uniform pores, possessing high flexural strength, high modulus, and high impact toughness, with comprehensive performance far exceeding that of traditional PET foam materials.

The application discloses a kind of thieno [2, 3-c] pyrazole compounds in preparation antitumor drug purposes, belong to pharmaceutical chemistry technical field.The application provides a kind of small molecule skeleton thieno [2, 3-c] pyrazole compound I and II, compound I is 2-oxo benzo [d] [1, 3] oxathiole-6-yl 1-(3-fluorophenyl)-3-methyl-1H-thieno [2, 3-c] pyrazole-5-carboxylate.Compound II is 1-(4-chlorophenyl)-N-[4-((4-ethylpiperazine-1-yl)methyl)phenyl]-3-methyl-1H-thieno [2, 3-c] pyrazole-5-formyl.Both have strong antitumor activity.Compound II has strong inhibition to a variety of human tumor cells, such as bone sarcoma MG63, breast cancer HCC1806, liver cancer LM3, lung cancer A549, colorectal cancer HCT-8 and the like, provides new candidate compounds for broad-spectrum antitumor drugs.

The invention provides pharmaceutical compositions comprising about 0.05 to 0.1% (w / v) cyclosporine dissolved in 1-perfluorobutyl-pentane for use in the topical treatment of dry eye disease and provides for dosing and treatment methods thereof. The invention further provides kits comprising such compositions.

The present invention relates to the field of organic synthesis, and more particularly to a process for the preparation of cycloethers of formula (I) comprising the cyclization of compounds of formula (II) in the presence of a Lewis acid, a protic acid having a pKa of 2 or less, or a mixture thereof.

The invention relates to the technical field of chemical synthesis, in particular to a preparation method of 1-benzyl alcohol-3-alkyl bicyclo [1.1. 1] pentane, which comprises the following steps: by taking aromatic aldehyde, [1.1. 1] propeller alkane and 4-alkyl substituted Hanss ester synthesized by aldehyde as initial raw materials and dichloroethane and the like as a solvent, carrying out a reaction under the protection of inert gas to obtain 1-benzyl alcohol-3-alkyl bicyclo [1.1. 1] pentane, and separating the 1-benzyl alcohol-3-alkyl bicyclo [1.1. 1] pentane from the 1-benzyl alcohol-3-alkyl bicyclo [1.1. 1] pentane. A three-component free radical coupling reaction is carried out under the illumination condition, and a 1-benzyl alcohol-3-alkyl bicyclo [1.1. 1] pentane product is synthesized in one step. The method has the advantages of mild reaction conditions, high reaction efficiency, low cost, simplicity and convenience in operation and the like, and a new method is provided for later structural modification of diaryl methanol drug molecules.

This invention discloses a cashew phenol quaternary ammonium salt compound and its preparation method, a catalyst for rigid polyurethane foam, and rigid polyurethane foam itself. The structure of the cashew phenol quaternary ammonium salt compound is shown below: n is 0-4. The cashew phenol quaternary ammonium salt contains an ester group, which improves compatibility with pentane, and the introduction of the ester group can reduce the thermal conductivity and increase the oxygen index; simultaneously, each molecule contains two tertiary amine structures, resulting in better catalytic effect per unit mass / molarity, i.e., higher catalytic efficiency. The cashew phenol quaternary ammonium salt compound can serve as a novel catalyst for rigid polyurethane foam. Compared with traditional polyurethane amine catalysts, its application in the field of rigid polyurethane foam has advantages such as safety, environmental friendliness, economy, high efficiency, and odorlessness.

The invention discloses a polycationic surfactant FCWS as well as a preparation method and application thereof, and belongs to the technical field of oilfield chemical assistants. The preparation method comprises the following steps: S1, dissolving 1, 5-diaminopentane in ethanol, adding epoxy chloropropane, and reacting at 25 DEG C for 24 hours to obtain an ethanol solution of an intermediate A; s2, an ethanol solution of the intermediate A and a dimethyl tertiary amine organic matter react for 36-48 h at the temperature of 80 DEG C, and the polycationic surface active agent FCWS is obtained. According to the invention, the prepared polycationic surfactant is adopted to modify the proppant, the settling velocity of the proppant is reduced, the proppant with excellent suspension capacity is obtained, and the proppant with excellent performance is provided for a reservoir yield-increasing transformation technology. The method is suitable for modifying the silicon dioxide-containing proppant.

The invention relates to an expiratory gas marker for evaluating a mental fatigue state, and a method and a device for identifying the mental fatigue state. The expired gas marker at least comprises an organic compound combination consisting of oxalic acid, 3-phenyllactic acid, benzene, acetone and 3-methylpentane; oxalic acid, 3-phenyllactic acid, benzene, acetone and 3-methylpentane in exhaled air are associated with mental fatigue, and a brand-new biomarker combination with higher specificity is provided. In addition, a new modal metabolic data is provided for mental fatigue discrimination, and a multi-modal mental fatigue diagnosis model based on VOCs-HRV-PVT is constructed.

This application discloses a method for the conversion of C4-C6 alkanes. In a reactor, a raw material containing hydrogen and C4-C6 alkanes is contacted with a catalyst and reacted to obtain a product containing small molecule hydrocarbons; the C4-C6 alkanes are selected from at least one of n-butane, isobutane, n-pentane, isopentane, and 2,3-dimethylbutane; the small molecule hydrocarbons are selected from at least one of ethane, propane, n-butane, and n-pentane; the catalyst is prepared by the following steps: (1) mixing clay and sol, spray drying to obtain microspheres with a diameter of 1-50 μm; (2) immersing the microspheres in an aqueous solution containing a noble metal precursor, drying I, calcining I, and treating with a hydrogen atmosphere to obtain a catalyst precursor; (3) mixing the catalyst precursor, molecular sieve, and additives, rolling to form spheres, drying II, calcining II, and reducing to obtain the catalyst.

The invention provides a foaming agent composition, premixed polyether polyol, a polyurethane composition, polyurethane foam and refrigeration equipment. The foaming agent composition comprises a foaming agent and a foam stabilizer, the foaming agent comprises bio-based cyclopentane and a CO2-based foaming agent, and the foam stabilizer comprises a bio-based siloxane-polyether copolymer. The environment-friendly property of the polyurethane foam can be improved.

The application discloses a method for normalizing isomeric alkanes, which comprises the following steps: contacting isomeric alkanes and hydrogen with a catalyst in a reactor to obtain normal alkanes; the isomeric alkanes are selected from at least one of isobutane and isopentane; the catalyst is composed of an acidic carrier, a noble metal active component supported on the surface of the acidic carrier and an auxiliary element; the noble metal active component is selected from at least one of Pt and Pd; the auxiliary element is selected from at least one of Ce, Sn, La, Fe, Co, Ni and Cu; and the carrier is selected from at least one of molecular sieve, Al2O3 modified SO4 2‑ -WO3-ZrO2; the mass ratio of the noble metal active component to the acidic carrier in the catalyst is 0.0001-0.01:1; and the mass ratio of the auxiliary element to the acidic carrier is 0.0001-0.008:1.

The utility model provides a crude cyclohexane refining recovery system which comprises a cyclohexane refining reactor and a cyclohexane rectifying tower, the bottom of the cyclohexane refining reactor is connected with the cyclohexane rectifying tower through a pipeline, and the top of the cyclohexane rectifying tower is connected with a first return tank through a first circulating water condenser and a cyclohexanol rectifying tower reboiler respectively. The first reflux tank is connected with the methylcyclopentane separating tower through a pipeline, the bottom of the methylcyclopentane separating tower is connected with the methylcyclopentane rectifying tower through a pipeline, and the bottom of the methylcyclopentane rectifying tower is connected with the cyclohexane rectifying tower through a pipeline. The device disclosed by the utility model is ingenious in design, can greatly improve the utilization efficiency of cyclohexane, and has good economic benefits.