The invention discloses a chromafenozide-containing insecticidal composition. The insecticidal composition contains an active ingredient A and an active ingredient B, the active ingredient A is selected from chromafenozide, and the active ingredient B is any compound of the following: tolfenpyrad, spirotetramat and metaflumizone, and the active ingredient A and the active ingredient are in a weight ratio of 1:70-70:1. The composition provided in the invention can control a plurality of pests, has an obvious synergistic effect, expands the insecticidal spectrum, and has high activity on Chilo suppressalis, beet armyworms, peach fruit moths, olethreutid, cotton bollworms, Pierisrapae Linne, plutella xylostella, aphids, thrips, phylloxeras, mealybugs, aleyrodid, scale insects, Cnaphalocrocis medinalis, pectinophora gossypiella, Mamestra brassicae, and Agrotis ypsilon on fruit trees, vegetables, rice, cotton and beans. Also, the dosage of pesticides is reduced, the pesticide residue on crops is lowered, and the environmental pollution is alleviated. Being safe to human and livestock, the insecticidal composition has good environmental compatibility, and pests are less likely to generate drug resistance.