The invention discloses a pesticide composition containing Chromafenozide, and provides an insecticidal composition which comprises an active component A and an active component B, wherein the active component A is Chromafenozide, the active component B is anyone compound selected from the following components: Lufenuron, Ethiprole, Chlorfenapyr, and Pyriproxyfen, and the weight ratio between the active component A and the active component B is 1:70-70:1. The composition can be used for controlling a plurality of insects with obvious synergistic effects and enlarged insecticidal spectrum, and has high activities for rice hoppers, yellow rice borers, rice stem borers, rice leaf rollers, aphids, Empoasca pirisuga, Phthorimaea operculella, Laspeyresia pomonella, Carposina niponensis, Lithocolletis ringoniella, Matsumuraeses phaseoli, Phyllocnistis citrella, Eriophyes oleivorus, scale insects, Spodoptera exigua, Pieris rapae, Anterhynchium flavomarginatum, thrips, Spodoptera litura, Helicoverpa armigera, and Etiella zinckenella. Pesticide dosage, residual quantity of the pesticide on crops, and environment pollution are reduced.