The present application belongs to the field of pharmaceutical
chemistry and
agricultural biotechnology, and particularly relates to a preparation method of
pyrone natural products and use thereof in preparing agricultural
antifungal drugs. Diaporthe kyushuensis Two novel
pyrone natural products are isolated from ZMU-48-1 for the first time. Valsa mali The two compounds exhibit significant inhibitory activity on Valsa mali (Miyabe & G.Yamada). Compared with traditional chemical synthetic fungicides, the compounds have the advantages of novel structure, strong targeting, environmental friendliness, slow
resistance development, and good prospects in the field of agricultural
antifungal drug research and development, and are particularly suitable for green control of
plant fungal diseases, and have important scientific research value and application value.