5 results about "Resistance development" patented technology

The present application belongs to the field of pharmaceutical chemistry and agricultural biotechnology, and particularly relates to a preparation method of pyrone natural products and use thereof in preparing agricultural antifungal drugs. Diaporthe kyushuensis Two novel pyrone natural products are isolated from ZMU-48-1 for the first time. Valsa mali The two compounds exhibit significant inhibitory activity on Valsa mali (Miyabe & G.Yamada). Compared with traditional chemical synthetic fungicides, the compounds have the advantages of novel structure, strong targeting, environmental friendliness, slow resistance development, and good prospects in the field of agricultural antifungal drug research and development, and are particularly suitable for green control of plant fungal diseases, and have important scientific research value and application value.

The application relates to the technical field of medical devices, and particularly discloses a hydrophilic coating angiography catheter and an intelligent lubricant release system thereof, wherein the hydrophilic coating angiography catheter comprises a data acquisition module, a basic running factor analysis module, a block area analysis module, a resistance factor analysis module, a resistance development analysis module and a lubricant release parameter determination module; the data acquisition module acquires a continuous angiography image sequence in front of the catheter and a real-time running distance; the basic running factor analysis module obtains a first running resistance factor of a basic running resistance factor based on image analysis of a blood vessel shape; the block area analysis module identifies a running block area, determines a latest relative position and a three-dimensional size of the running block area; the resistance factor analysis module combines related data to perform combined resistance effect analysis, obtains a running combined resistance factor and a second running resistance factor; the resistance development analysis module constructs a resistance factor analysis tree, fits a resistance change curve, and analyzes a plurality of resistance development factors; and the lubricant release parameter determination module outputs a lubricant release parameter control instruction based on the above factors; scientific and accurate control of lubricant release is realized, and the scientificity and effectiveness of catheter operation are improved.

The present invention belongs to the field of pesticides and insecticides and relates to an insecticidal composition. The insecticidal composition comprises active ingredients A and B, wherein active ingredient A is a compound of formula (I) and active ingredient B is either flubendiamide or thiocyclam. The mass ratio of active ingredient A to active ingredient B is 1:35 to 33:1. The insecticidal composition of the present invention has the advantages of enhancing synergy and delaying resistance development, and is used for controlling resistant pests.

The present invention relates to a composite probiotic for preventing and treating infectious pneumonia and use thereof. The composite probiotic for preventing and treating infectious pneumonia consists of the Lactobacillus acidophilus LA85 strain and the Lactobacillus plantarum Lp05 strain. The two strains can cooperate with each other and promote each other, resulting in a synergy in the prevention and treatment of infectious pneumonia. When the same amount of bacteria is used, compared with a strain intervention lacking either strain, the combination of the two strains has a significantly improved effect in the prevention and treatment of infectious pneumonia. Moreover, both strains are probiotics. The product has a high level of safety and a low risk of resistance development.

This invention relates to an insecticide composition and its application method. The composition comprises two active components, A and B, wherein component A is selected from benzamide compounds represented by general formula I, and component B is selected from flupyrimin. The composition of this invention has advantages such as significant synergistic effect and delayed resistance development, and can be used to control a variety of pests.