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97 results about "Abiotic stress" patented technology

Abiotic stress is the negative impact of non-living factors on the living organisms in a specific environment. The non-living variable must influence the environment beyond its normal range of variation to adversely affect the population performance or individual physiology of the organism in a significant way.

Application of rice OsPBL8 gene in enhancing resistance of rice to magnaporthe oryzae

The invention relates to the technical field of biology, in particular to application of a rice OsPBL8 gene in enhancing resistance of rice to magnaporthe oryzae. The rice OsPBL8 gene is a rice endogenous gene participating in the processes of plant growth and development, abiotic stress response, hormone signal channel regulation and control and the like. The invention provides application of the OsPBL8 gene in the field of disease resistance, the OsPBL8 gene is overexpressed through gene editing, and the expression quantity of receptor-like cytoplasm kinase OsPBL8 in plants is increased, so that a plurality of signal channels are regulated and controlled, and the germ resistance of the plants is synergistically improved. By adjusting key hub nodes of plant targeted immune signal transduction, more lasting broad-spectrum disease resistance can be provided, good universality is achieved, disease resistance and growth can be balanced, good practicability is achieved, and improvement of disease resistance of various rice varieties is facilitated.
Owner:SUZHOU UNIV

Method for analyzing alfalfa stress resistance gene function based on metabonomics and breeding method

The invention relates to the technical field of plant breeding, and particularly discloses a metabonomics-based alfalfa stress resistance gene analysis function and a breeding method. The core of the method is that screening is carried out by combining a tissue culture technology with metabolic intervention; an alfalfa explant is inoculated into an induction culture medium containing a specific metabolic pathway regulator for metabolic intervention culture; then transferring the obtained callus to a verification culture medium containing the metabolism regulator and an abiotic adversity stress factor at the same time, and carrying out metabolism mark verification and screening; and finally regenerating the screened cell line into a complete plant. According to the method, metabolic pressure is actively applied to the cellular level, and dual verification screening is implemented, so that early-stage, efficient and accurate breeding of the stress-resistant alfalfa material is realized, and the technical problems of long period, low efficiency and insufficient utilization of metabolic information in traditional breeding are solved.
Owner:HEILONGJIANG BAYI AGRICULTURAL UNIVERSITY

Compositions containing abiotically-stressed plant-derived exosome-like nanoparticles

The present disclosure provides a composition containing a purified population of plant-derived exosome-like nanoparticles isolated from tissue of a vascular plant, wherein the exosome-like nanoparticles comprise a tuned cargo comprising a protein signature and an miRNA signature, wherein the tuned cargo of the plant-derived exosome-like nanoparticles is a result of exposure of the plant to combinations of abiotic stress conditions that cause the plant to modulate its signaling pathways and metabolism to ensure its survival in a challenging environment. The tuned cargo of the plant-derived exosome-like nanoparticles can modulate bioactivities of mammalian cells directly or indirectly. The present disclosure also provides a method for improving appearance of human skin and human hair health, including eyelashes and eyebrows, comprising applying a composition comprising the abiotically stressed plant-derived exosome-like nanoparticles containing the tuned cargo and a carrier; and applying the composition topically.
Owner:EXOTROPIN LLC

MaDREB1F gene and application thereof

The application discloses a MaDREB1F gene, and a nucleotide sequence of the MaDREB1F gene is shown as SEQ ID NO:1. Experimental research results reveal a mechanism of MaDREB1F in mediating non-biological stress resistance of bananas, and determine new targets (MaAOC4, MaACO20 and MaERF11) of MaDREB1F, which are beneficial to design breeding strategies to improve the resistance of crops to cold and drought stress.
Owner:HAIKOU EXPERIMENTAL STATION CHINESE ACAD OF TROPICAL AGRI SCI +1

Application of betula platyphylla BpmiR156C gene in regulating and controlling plant height of betula platyphylla

The invention provides application of a white birch BpmiR156C gene in regulating and controlling the plant height of white birch, and belongs to the technical field of plant genetic engineering. The plant height of the white birch is regulated and controlled through high expression of the white birch BpmiR156C gene, the plant height of the white birch is influenced, then forest plants are promoted to cope with biological and abiotic stress, and cultivation of high-quality forest trees is guaranteed.
Owner:NORTHEAST FORESTRY UNIV

Exiguobacterium acetylbacter and application thereof

PendingCN121653006ABiocidePlant growth regulatorsBiotechnologyExiguobacterium
The invention relates to the technical field of microorganisms, in particular to an Exiguobacterium aceticum and application thereof. The Exiguobacterium aceticum strain is classified and named as Exiguobacterium aceticum, the strain number is H102, the Exiguobacterium aceticum strain is preserved in the China General Microbiological Culture Collection Center (CGMCC) on December 24, 2025, and the preservation number is CGMCC No.37157. The Exiguobacterium aceticum strain has the advantages that the Exiguobacterium aceticum strain can be used for preparing the Exiguobacterium aceticum strain; the strain has strong saline-alkaline tolerance, drought tolerance and high temperature resistance, and a foundation is provided for colonization of the strain. Meanwhile, the strain has the functional characteristics of producing acetoin, polysaccharide and polyglutamic acid and the like, can effectively provide nutritional ingredients for plant growth and reduce the harm of abiotic stress to the plants, and therefore, the strain has important application value in the aspects of improving saline-alkali soil, improving abiotic stress resistance of the plants, promoting plant growth and the like.
Owner:NANJING TECH UNIV

Plants with increased yield, biomass and stress tolerance

The present invention relates to a transgenic plant having increased biomass, yield, and / or abiotic stress tolerance. In particular, the present invention relates to a transgenic plant or plant cell into which a nucleic acid molecule encoding an RNA demethylase FTO (fat mass associated with obesity) protein is introduced. The present disclosure also provides methods of producing plants having increased biomass, yield, and / or abiotic stress tolerance.
Owner:AVNER CORP

PROSiCAPE14 gene and application of protein encoded by PROSiCAPE14 gene in improving salt tolerance of plants

The invention belongs to the technical field of plant genetic engineering, and particularly relates to application of a PROSiCAPE14 gene and a protein encoded by the PROSiCAPE14 gene to improvement of plant salt tolerance. According to the invention, it is found for the first time that salt stress can cause down-regulation of the expression of the millet PROSiCAPE14 gene. Under a salt treatment condition, the plant height and the root length of a PROSiCAPE14 gene coded small peptide externally applied to millet and a constructed PROSiCAPE14 gene overexpression strain are obviously worse than those of a control group, and the plant height and the root length of a PROSiCAPE14 gene silent plant are obviously better than those of the control group. It is indicated that the PROSiCAPE14 gene plays an important role in the salt stress response process of the millet, and a foundation is provided for further research on the effect of the CAPE14 gene in the adaptation of the millet to abiotic stress and other possible biological functions.
Owner:SHANDONG NORMAL UNIV

Agrochemical adhesion synergist based on plant-derived protein, and preparation method therefor and use thereof

PCT designated stageWO2026098386A1BiocidePlant growth regulatorsProtein stabilizationPlant growth
The present application relates to the field of agrochemical adjuvants, and relates to an agrochemical protein adhesion synergist based on a plant-derived protein, and a preparation method therefor and a use thereof. Said synergist comprises the following raw materials in parts by weight: 20-500 parts of a plant-derived protein, 50-450 parts of a protein dispersant, and 20-350 parts of a protein stabilization and protection agent. The product of the present application improves the utilization rate of agrochemicals and reduces problems such as grain yield reduction and environmental pollution caused by the loss of agrochemicals. Moreover, as the protein degrades into amino acids, plant growth can be promoted, and the resistance of plants to abiotic stress is improved, thereby reducing dosage of agrochemicals while enhancing efficacy of agrochemicals.
Owner:SHAANXI NORMAL UNIV +1

Application of knockout rice OsWAK55 gene in improvement of drought resistance and salt resistance of rice

The invention relates to the technical field of plant genetic engineering, and discloses application of a knockout rice OsWAK55 gene in improvement of drought resistance and salt resistance of rice. According to the invention, a candidate gene is subjected to CRISPR (clustered regularly interspaced short palindromic repeats) knockout, a mutant is subjected to phenotype identification and stress screening, the gene OsWAK55 for regulating and controlling rice drought and salt stress is cloned, a nucleoside sequence of the gene OsWAK55 is shown as SEQ ID NO: 1, and a protein sequence coded by the gene is shown as SEQ ID NO: 2. A stress experiment in the seedling stage of the mutant shows that after the gene is mutated, the drought resistance and the salt resistance of the rice are enhanced, and the enhancement of the drought resistance is related to the condition that the mutant seedling has a more developed and robust root system. Therefore, the gene OsWAK55 is knocked out, so that the improvement of the abiotic stress resistance of the rice is facilitated.
Owner:YUNNAN UNIV

A method for cultivating castor beans using abiotic stress

This invention discloses a method for cultivating castor beans using abiotic stress, belonging to the field of castor bean cultivation technology. The method includes planting castor beans in a cultivation substrate containing zinc ions, and gradually lowering and then restoring the growth temperature of the castor bean seeds. Based on the castor bean's strong antioxidant defense system, this invention further regulates the castor bean through low-temperature acclimation. Gradually reducing temperature stress can induce the activity of the castor bean's antioxidant enzyme system, enhancing its stress resistance and cold resistance, thus mitigating the impact of low-temperature disasters on castor beans. This invention provides a theoretical reference for the promotion and utilization of castor beans and the cultivation and development of stress-resistant castor bean varieties.
Owner:BAICHENG NORMAL UNIV

Gene bHLH35 for promoting anthocyanin accumulation of plants and application thereof

The present invention relates to a method for cultivating transgenic plants having increased anthocyanin content and enhanced tolerance to biotic and abiotic stress environments. The method comprises transferring a bHLH35 gene into recipient plants using a genetic engineering transformation method, to obtain transgenic plants having increased anthocyanin content and tolerance to biotic and abiotic stress environments. The bHLH35 gene may be selected from a ChbHLH35 gene from Corydalis hemidicentra or an AtbHLH35 gene from Arabidopsis thaliana.
Owner:LANZHOU UNIV

Phyllostachys edulis pe masr1 gene, biological material and application thereof

The present application belongs to the technical field of plant genetic engineering, and particularly relates to a Phyllostachys edulis PeMASR1 gene, biological material and application thereof. The PeMASR1 gene provided by the present application is a new gene discovered in the study of cold tolerance of Phyllostachys edulis leaves, the nucleotide sequence of which is shown as SEQ ID NO:1, and the amino acid sequence of the encoded protein is shown as SEQ ID NO:2. Through gene cloning, expression and comparative analysis, the phylogenetic position of the Phyllostachys edulis PeMASR1 gene and the important role thereof in the research of plant response to abiotic stress mechanism and photosynthesis are revealed. Overexpression in Columbia-type Arabidopsis plants can make the rosette leaves of the plants early senesce; and the plants show a more stress-tolerant phenotype than wild-type Arabidopsis in response to cold stress, drought stress and salt stress and other abiotic stresses.
Owner:NANJING FORESTRY UNIV

Multifunctional phosphorus-solubilizing and potassium-releasing bacteria wzx-pkb-1 and application thereof

This application relates to the field of agricultural microbiology technology, and in particular to a multifunctional phosphate-solubilizing and potassium-solubilizing bacterium WZX-PKB-1 and its applications. The multifunctional phosphate-solubilizing and potassium-solubilizing bacterium WZX-PKB-1 is classified and named... Priestia sp. WZX-PKB-1 was deposited at the Guangdong Provincial Center for Microbial Culture Collection on January 28, 2026, with accession number GDMCC NO: 67763. WZX-PKB-1 exhibits significant tolerance to multiple abiotic stresses, including high temperature, salinity, drought, and mixed heavy metals, and demonstrates effective phosphorus and potassium release capacity under these conditions, making it suitable for desert soil improvement and ecological restoration.
Owner:INNER MONGOLIA AGRICULTURAL UNIVERSITY

Composition comprising a biochar and an aqueous extract of a seed legume

Composition comprising a biochar and an aqueous extract of a seed legume. The present invention relates to a composition comprising a biochar and an aqueous extract of a seed legume, a method for preparing said composition and the use of the composition to promote seed germination, to improve the nutrient utilization efficiency of a seed, to promote seedling development and to improve seedling tolerance to abiotic stress.
Owner:AGRO INNOVATION INT

Application of StNCED3 gene in improving abiotic stress resistance of potato

PendingCN122382023AImprove drought resistanceincrease resourcesBiotechnologyMolecular breeding
This invention relates to the field of biotechnology, specifically to... StNCED3 The application of genes in improving the abiotic resistance of potatoes: This invention involves constructing... StNCED3 The screening and identification of gene overexpression vectors and transgenic lines, and their application in improving potato resistance to drought and low-temperature stress, revealed the overexpression of... StNCED3 The gene can significantly enhance the drought and cold resistance of potato plants, providing core functional genes and high-quality breeding materials for molecular breeding of potatoes for drought and cold resistance. It effectively solves the technical bottlenecks of weak drought and cold resistance of the current main potato varieties and unstable yield in arid and low-temperature production areas, and has important theoretical research value and industrial application prospects.
Owner:YUNNAN NORMAL UNIV

A corn new variety breeding cultivation device and cultivation method

The application provides a corn new variety breeding cultivation device and cultivation method, relates to the corn variety breeding technical field, and includes a support platform, which is arranged with multiple groups of cultivation bins in an array; the cultivation bin is slidably connected to the support platform through a driving mechanism, and a HEPA filter screen is connected to the cultivation bin; both sides of the cultivation bin are provided with observation windows, and multiple observation mechanisms are arranged on the support platform; the front end of the cultivation bin is provided with a docking mechanism; the bottom of the front end and the bottom of the rear end of the cultivation bin are respectively provided with abutment mechanisms; the front end and the rear end of the cultivation bin are respectively provided with opening and closing mechanisms; the cultivation bin is provided with an environment simulation mechanism; the cultivation bin is connected with a stress application window; the application integrates multiple environment simulations, multiple stress applications, automatic observation and unit recombination, greatly improves the breeding efficiency, realizes the simulation of different regional soil-climate conditions, can accurately combine multiple biological and non-biological stresses, and speeds up the breeding process of the corn new variety.
Owner:SHANXI AGRI UNIV

n-hBGP AGRICULTURAL COMPOSITION

PCT designated stageWO2026143177A1Agricultural cropsAbiotic stress
In one arrangement a functional composition for delivery to the surface of a plant is provided. In one particular implementation, the functional composition is configured to regulate abiotic stressors encountered by a plant or other agricultural crop during its growth cycle. By way of non-limiting example, a functional agricultural composition is provided, where the functional agricultural composition comprises at least one osmolytic compound configured to be provided in a solution with water and applied directly to the surface of a plant or other agricultural crop.
Owner:ADJ PARTNERS LLC

Imidazole-type abscisic acid receptor antagonists and their use

The present invention relates to a novel type of compounds which modulate the activity of Abscisic Acid (ABA) receptors in plants. More particularly, such novel compounds are acting as ABA antagonists, which specifically and potently block activation of clade III ABA receptors including but not only PYL1, while another subfamily of compounds has agonistic mode of action promoting activation of the receptor and the ABA signaling pathway. These compounds are, therefore, applicable in different fields of modulating target plant seed germination, modulating target plant growth, modulating tolerance to drought and abiotic stress, modulating fruit ripening, or modulating immunity of a target plant. More particularly, said compounds can be used to stimulate the germination of plant seeds, either under conditions favorable for the growth of crop plants, or unfavorable for the survival of weeds. The compounds can also be used to enhance plant growth under growing conditions where water is not a limiting factor on plant growth. The selectivity of the compounds for clade III ABA receptors will prevent unwanted effects from blocking other ABA receptor subtypes (for example in clade II and clade I groups) present in the plants of interest. The present invention also provides corresponding agrochemical compositions comprising such novel compounds.
Owner:EURO LAB FUER MOLEKULARBIOLOGIE EMBL +2

Application of ginseng glycosyl transferase UGT84K2 in improving abiotic stress resistance of plants

The invention relates to the field of plant genetic engineering, in particular to application of ginseng glycosyl transferase UGT84K2 to improvement of abiotic stress resistance of plants. The ginseng glycosyl transferase UGT84K2 gene is transferred into a model plant arabidopsis thaliana for research, an overexpression strain of the ginseng glycosyl transferase UGT84K2 is constructed, salt-resistant and drought-resistant adversity stress treatment is performed, and results show that under the conditions of adversity high salt (NaCl), drought stress (osmotic stress) and the like, the expression quantity of the ginseng glycosyl transferase UGT84K2 is up-regulated, and the expression quantity of the ginseng glycosyl transferase UGT84K2 is up-regulated. And the ginseng glycosyl transferase UGT84K2 overexpression strain shows stronger tolerance under the adverse condition, which reflects that the stress resistance of the ginseng glycosyl transferase UGT84K2 overexpression strain can be enhanced through glycosylation modification.
Owner:LINYI UNIVERSITY

Humic acid-fulvic acid composite plant growth promoter and application thereof

PendingCN121621362ABiocidePlant growth regulatorsBiotechnologyPlant regulators
The invention relates to the technical field of plant growth promotion, and particularly discloses a humic acid-fulvic acid composite plant growth promoter and application thereof. The accelerant is prepared from the following components in percentage by mass: 30 to 38 percent of fulvic acid compound, 4 to 8 percent of seaweed extract, 2 to 5 percent of marine animal source amino acid, 0.5 to 2 percent of chitosan oligosaccharide, 0.5 to 1.5 percent of microorganism source lipopeptide, 0.03 to 0.5 percent of plant growth composite regulator, 1.2 to 2.5 percent of osmotic regulator, 0.3 to 1.0 percent of salicylic acid, 2 to 5 percent of composite trace element and the balance of water. The fulvic acid, the seaweed extract, the amino acid, the chitosan oligosaccharide, the lipopeptide, the precisely compounded plant regulator and the nutrient elements generate a remarkable synergistic effect, the effect of the fertilizer is comprehensively superior to that of a single conventional fertilizer, crops can be effectively helped to cope with abiotic stress, the yield of the crops is increased, and the yield of the crops is increased. And the method has a wide popularization and application prospect.
Owner:SHANDONG YOUGENG AGRICULTURAL DEVELOPMENT GROUP CO LTD

Animal amino acid-derived biostimulant from wool fiber and production method thereof

The invention relates to an animal amino acid-derived biostimulant obtained by utilizing wool fiber waste generated from leather production for use in the field of agriculture, and the production method thereof. The biostimulant of the invention is produced by alkaline hydrolyzation method. Said biostimulant is used to support plant growth and development against abiotic stress factors, and to solve drought and salinity-induced problems, particularly in dry agriculture.
Owner:EGE ÜNİVERSİTESİ İDARİ & MALİ İŞLERDAİRE BŞK

Melilotus albus MaWRKY76 gene and application thereof

The invention relates to the technical field of biology, in particular to a sweet clover MaWRKY76 gene and application thereof.The sweet clover MaWRKY76 gene is cloned firstly, and the expression mode of the sweet clover MaWRKY76 gene under the salt stress condition is analyzed through real-time quantitative PCR; by constructing a yeast heterologous expression vector, the MaWRKY76 is proved to be capable of remarkably improving the salt tolerance of yeast cells. A plant overexpression and RNAi vector is further constructed, sweet clover hairy roots are transformed, and the result shows that the MaWRKY76 not only participates in regulating the symbiotic process of root nodules, but also plays a key role in resisting salt stress. The genetic strategy based on MaWRKY76 can effectively improve symbiotic nitrogen fixation efficiency, plant sustainability and yield of sweet clover under salt stress, provides a theoretical basis for efficient nodulation and nitrogen fixation of leguminous plants under adversity stress, and has positive significance in promoting green sustainable agricultural development.
Owner:LANZHOU UNIV

Method for screening arbuscular mycorrhizal fungi in soil

The invention belongs to the technical field of microbiological detection and soil biology, and particularly relates to a method for screening arbuscular mycorrhizal fungi in soil, which comprises the following steps: preparing a soil propagule suspension, realizing single individual separation and physical isolation of propagules by using a microecological niche array, and screening the arbuscular mycorrhizal fungi in the soil. The strain is co-cultured with a sterile host root system under a specific abiotic stress condition, and the stress-tolerant functional strain is directly obtained through microscopic monitoring, positive symbiont confirmation and molecular identification. According to the technical scheme, competitive bias voltage can be avoided, the slave mycorrhizal fungi purified strains with low phosphorus, drought or saline-alkali tolerance are efficiently screened out, and screening objectivity and functional targeting are remarkably improved.
Owner:GANSU AGRI UNIV

Application of rice transcription factor OsRAV1 gene in regulating seed storage tolerance and germination stage salt tolerance

The application discloses a rice transcription factor OsRAV1 application in regulating seed storage tolerance and salt tolerance in germination stage, belongs to the field of plant molecular biology and plant breeding. OsRAV1 The application discloses that the gene regulates seed vigor, and knockout OsRAV1 will significantly reduce seed vigor, and the seed is not storage tolerant. OsRAV1 significantly improves seed vigor after storage and live seedling rate under salt stress. The application can be used to solve the problems of rice seed not storage tolerant, low seedling rate, uneven seedling and poor abiotic stress tolerance in the live process, and has wide application prospect.
Owner:YANGZHOU UNIV

A drought-inducible promoter of cotinus coggygria and application thereof

ActiveCN120400149BThe degree of staining is deepenedImprove expression levelVector-based foreign material introductionAngiosperms/flowering plantsBiotechnologyHeterologous
The application discloses a drought-inducible promoter of Cotinus coggygria and application thereof, a DNA sequence of the promoter is shown as SEQ ID No. 1, proCcDT1 is cloned from a promoter region of a CcDT1 gene of the Cotinus coggygria and is verified through experiments. First, elements of the promoter region are analyzed, and the result shows that the elements contain multiple cis-acting elements that can be involved in response to abiotic stress. Then, proCcDT1-GUS transgenic plants are treated through 10% PEG simulation drought, and it is found that GUS staining of the transgenic plants is enhanced, so it can be concluded that the GUS expression level driven by the promoter is increased under drought induction conditions, and it is also proved that the promoter can be induced by drought stress. The promoter proCcDT1 is introduced into an Arabidopsis genome through genetic transformation technology, so that the promoter can be stably induced by drought stress in a heterologous plant, and the practical application has important value for cultivating drought-resistant Cotinus coggygria varieties.
Owner:SOUTHWEST UNIV

Application of LuPDH-E1 beta 1 gene in regulating plant fatty acid synthesis and salt and drought tolerance

ActiveCN116479036BBiotechnologyFatty acid biosynthesis
The application provides application of a LuPDH-E1beta1 gene in regulating plant fatty acid synthesis, and after overexpression of the LuPDH-E1beta1 gene in plants, the amount of plant fatty acid synthesis can be increased. The application also provides application of the LuPDH-E1beta1 gene in regulating plant salt tolerance and drought resistance, and after overexpression of the LuPDH-E1beta1 gene in plants, the salt tolerance and drought resistance of a PDH-E1beta1 gene deletion plant can be increased. Through exploration of the function of the LuPDH-E1beta1 gene in plant seed oil metabolism and response to abiotic stress, the application of the LuPDH-E1beta1 gene in regulating plant fatty acid synthesis and salt tolerance and drought resistance is given, and a blank in the application of the LuPDH-E1beta1 gene in genetic engineering is filled.
Owner:NORTHWEST A & F UNIV

Evaluation method suitable for top-free flooding resistance of tropical water lily stock plants and fetal seedlings

PendingCN121890476AFlowers cultivationMeasurement devicesStem lengthLeaf cell
The invention discloses a method suitable for evaluating the top-free flooding resistance of a tropical water lily stock plant and a fetal seedling, and relates to the field of adversity stress, and the water lily stock plant or the fetal seedling is subjected to top-free flooding treatment with different time lengths. Determining the damage condition by taking the leaf length, the leaf width, the leaf ear length, the leaf area, the stem length, the stem diameter, the chlorophyll content and the leaf cell structure of the normally growing and waterlogged plant as evaluation indexes, and calculating the leaf rot index and the flood tolerance index of the to-be-detected water lily according to the flood damage leaf rot area to realize evaluation. According to the method, the influence of waterlogging on the external phenotype and internal structure of the water lily is considered, the difference of waterlogging treatment on plant ages is considered, the waterlogging resistance is determined through phenotype and cell structure changes, the waterlogging resistance level of the tropical fetal water lily is determined, and the method has the remarkable advantages of being short in evaluation period, visual, reliable and the like. The method is beneficial for promoting innovation of water lily flooding-resistant germplasm and breeding of a flooding-resistant fetal water lily variety, and a new method is provided for research of a water lily flooding-resistant mechanism.
Owner:SOUTHWEST FORESTRY UNIVERSITY

Compositions containing abiotically-stressed plant-derived exosome-like nanoparticles

The present disclosure provides a composition containing a purified population of plant-derived exosome-like nanoparticles isolated from tissue of a vascular plant, wherein the exosome-like nanoparticles comprise a tuned cargo comprising a protein signature and an miRNA signature, wherein the tuned cargo of the plant-derived exosome-like nanoparticles is a result of exposure of the plant to combinations of abiotic stress conditions that cause the plant to modulate its signaling pathways and metabolism to ensure its survival in a challenging environment. The tuned cargo of the plant-derived exosome-like nanoparticles can modulate bioactivities of mammalian cells directly or indirectly. The present disclosure also provides a method for improving appearance of human skin and human hair health, including eyelashes and eyebrows, comprising applying a composition comprising the abiotically stressed plant-derived exosome-like nanoparticles containing the tuned cargo and a carrier; and applying the composition topically.
Owner:EXOTROPIN LLC