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829 results about "Malic acid" patented technology

Malic acid is an organic compound with the molecular formula C₄H₆O₅. It is a dicarboxylic acid that is made by all living organisms, contributes to the sour taste of fruits, and is used as a food additive. Malic acid has two stereoisomeric forms (L- and D-enantiomers), though only the L-isomer exists naturally. The salts and esters of malic acid are known as malates. The malate anion is an intermediate in the citric acid cycle.

Long-term fire retardant with corrosion inhibitors and methods for making and using same

A forest fire retardant composition contains a retardant compound that includes a potassium salt. The potassium salt may include a potassium salt of an organic acid, a potassium salt of an inorganic acid, or mixtures thereof. The organic acid may include formic acid, acetic acid, propanoic acid, butanoic acid, lactic acid, oxalic acid, malic acid, gluconic acid, tartaric acid, uric acid, malic acid, or citric acid. The inorganic acid may include sulfuric acid, phosphoric acid, carbonic acid, or hydrochloric acid. The composition may be in the form of a dry concentrate, a liquid concentrate, or a final diluted product. The final diluted product is effective in suppressing, retarding, and controlling forest fires while exhibiting corrosion resistance and low toxicity.
Owner:PERIMETER SOLUTIONS LP

Preparation method of make-up fixing and brightening pressed powder

PendingCN120284749ACosmetic preparationsBody powdersCaprylyl GlycolMeth-
The preparation method comprises the following steps: firstly, uniformly stirring and mixing synthetic fluorophlogopite, silica, polymethylsilsesquioxane, boron nitride, bismuth oxychloride, zinc stearate, aluminum starch octenylsuccinate, mica, aluminum oxide, hydrolyzed sodium hyaluronate and toner in a stirring homogenizer; then uniformly mixing polydimethylsiloxane, octyldodecanol stearoyloxy stearate, isoamyl laurate, diisostearyl malate, phenoxyethanol and caprylyl glycol, and heating to 45 + / -5 DEG C; pouring the mixture into an oil spraying barrel of a stirring homogenizer, uniformly stirring and mixing while spraying oil, crushing, then carrying out airflow crushing, sieving the material, putting the sieved material into a mold plate, and carrying out compression molding, so as to obtain a pressed powder block; and putting the mixture into a packing material powder box to obtain the make-up fixing and brightening pressed powder. The pressed powder is prepared by adding an airflow crushing process, the particle size of the powder is smaller, the powder is dispersed more uniformly, the powder is pressed into the solid pressed powder, and the phenomenon of powder flying is well reduced while makeup fixing and brightening effects are achieved.
Owner:저장 아얀 바이오텍 컴퍼니 리미티드 +1

Whitening and freckle-removing composition containing composite plant extract and preparation method of whitening and freckle-removing composition

The invention relates to a whitening and freckle-removing composition containing a composite plant extract and a preparation method of the whitening and freckle-removing composition, and belongs to the technical field of cosmetics. The composition disclosed by the invention is prepared from the following raw materials in parts by weight: 5 to 8 parts of pineapple leaf nano cellulose, 10 to 16 parts of modified starch, 10 to 15 parts of longan seed extract, 6 to 10 parts of mulberry bark extract, 5 to 8 parts of nicotinamide and 8 to 10 parts of hyaluronic acid. The pineapple leaf nanocellulose contains flavonoid and phenolic compounds with double-bond, conjugated double-bond and triple-bond structures, and modified starch is used as a filler to form a film on the surface of skin, so that an anti-ultraviolet protection wall is formed; the betaine-malate ionic liquid is added into the longan seeds, so that extraction of polyphenol in the longan seeds is improved, the longan seeds have acid-base buffering capacity, an auxiliary does not need to be added to adjust the pH value, the components of the prepared composition interact, and the whitening and freckle removing effects are achieved from multiple aspects of ultraviolet resistance, oxidation resistance, inflammation resistance and skin metabolism improvement.
Owner:GUANGZHOU QIAOZIYAN COSMETICS CO LTD

A kind of jelly candy containing DHA and preparation method thereof

The present invention provides a gel candy containing DHA and a preparation method thereof. The gel candy containing DHA of the present invention is made of the following raw materials: 1-10 parts of edible colloid, including one or more of pectin, gelatin, carrageenan, agar, starch, locust bean gum, and xanthan gum; 75-90 parts of sweetener; 5-15 parts of DHA microcapsule powder; 2-10 parts of moisture retainer; 0.5-5 parts of acidity regulator-buffer salt pair, including one or more of citric acid and its sodium salt or potassium salt, DL-malic acid and its sodium salt, lactic acid and its sodium salt. The present invention also provides a preparation method for the above-mentioned gel candy, adding DHA microcapsule powder and acidity regulator-buffer salt pair in the last stage before casting and molding and mixing evenly; it can be cast into a solid or sandwich product, and the moisture content of the obtained gel candy is 8-20%. The gel candy of the present invention has no fishy smell during the shelf life of 18 months, and the product does not return to sand or melt.
Owner:HERBALIFE (SHANGHAI) BIOTECHNOLOGY CO LTD

Method for producing L-malic acid by adding ethylene glycol and construction and application of malic acid producing escherichia coli

PendingCN120118962ABacteriaMicroorganism based processesPhosphoenolpyruvate carboxylaseEscherichia coli
The invention relates to a method for increasing the yield of L-malic acid produced by fermentation by adding ethylene glycol, which comprises the following steps: constructing genetic engineering escherichia coli, and introducing ethylene glycol metabolism genes (overexpression) including glycerol dehydrogenase, lactaldehyde reductase, lactaldehyde dehydrogenase and the like; and overexpression of other genes involving malic acid production, such as malic acid synthase, phosphoenolpyruvate carboxylase and malic acid export protein. The gene engineering strain is an E.coli BW25113 strain of which ldhA, pta, poxB, adhE, pflB, mgsA, frdA, maeA, maeB, yqhD, ycdW and iclR genes are substantially inactivated, and the deleted genes are beneficial to reducing the generation of metabolic byproducts and increasing the accumulation of malic acid. The genetic engineering strain is subjected to fermentation culture by taking glucose and ethylene glycol as carbon sources, and L-malic acid is separated from a culture after culture is finished.
Owner:MINT BIOTECH LTD

Fresh-keeping composite solution sprayed before picking of fruits in cold-chain logistics transportation and preparation method of fresh-keeping composite solution

The invention provides a fresh-keeping composite solution sprayed before picking fruits in cold-chain logistics transportation and a preparation method of the fresh-keeping composite solution, and relates to the field of fruit fresh keeping. The fresh-keeping composite solution is prepared from the following raw materials in parts by weight: 2.8 to 3.5 parts of schizochytrium limacinum powder, 2.3 to 2.8 parts of salvia officinalis extract, 1.8 to 2.2 parts of brown algae extract, 1.2 to 1.8 parts of banana peel polysaccharide, 0.8 to 1.2 parts of sodium carboxymethyl cellulose, 0.8 to 1.2 parts of tea polyphenol, 0.8 to 1.2 parts of beta-cyclodextrin, 0.8 to 1.2 parts of sodium alginate, 0.8 to 1.2 parts of calcium chloride, 0.4 to 0.6 part of olive oil, 0.1 to 1 part of malic acid and 80 to 90 parts of water. The composite fresh-keeping solution is developed for cold-chain logistics transportation of fruits and is applied before fruit picking, the synergistic effect of multiple natural components is utilized, sterilization and oxidation resistance can be achieved, the growth of microorganisms can be effectively inhibited, the respiration rate of the fruits is reduced, the moisture of the fruits is kept, and the optimal fresh-keeping effect is achieved. The fruit preservative is sprayed before the fruits are picked, so that decay and quality reduction of the fruits in the cold-chain logistics transportation process can be effectively reduced.
Owner:HUNAN INST OF APPLIED TECH

Method for detecting diastereoisomers in nenofloxacin malate sodium chloride injection

The invention provides a method for detecting diastereoisomers in a nerofloxacin malate sodium chloride injection. The method comprises the following steps: separating optical isomers of the nerofloxacin malate sodium chloride injection by adopting a liquid chromatography; wherein the chromatographic condition of the liquid chromatography comprises a mobile phase, the mobile phase comprises a mobile phase A and a mobile phase B, the mobile phase A is a trifluoroacetic acid solution, and the mobile phase B is methanol-tetrahydrofuran. According to the technical scheme, a trifluoroacetic acid solution is adopted as a mobile phase A, methanol-tetrahydrofuran is adopted as a mobile phase B, tetrahydrofuran is added in the mobile phase B, the peak pattern of a main peak is improved, the trailing factor is 1.06, the operation time can be shortened, and the peak pattern of the main peak is improved.
Owner:HANGZHOU JIANDONG WEIYE MEDICINE CO LTD

Eutectic solvent and application thereof

The invention relates to the technical field of plant effective component extraction, in particular to a deep-eutectic solvent and application thereof, and the deep-eutectic solvent is composed of anhydrous betaine, DL-malic acid and deionized water. The eutecticevaporate solvent is applied to extraction of momordica grosvenori polysaccharide, ultrasonic waves are combined with the eutecticevaporate solvent, in addition, extraction conditions of crude momordica grosvenori polysaccharide are optimized, and a new method is provided for efficient and green extraction of momordica grosvenori polysaccharide. The new method not only expands the application range of DESs in natural product extraction, but also provides important technical reference for industrial development of momordica grosvenori polysaccharide.
Owner:GUANGXI UNIV FOR NATITIES +1

Saccharomyces cerevisiae, fungicide, application and screening method

The invention belongs to the technical field of microorganisms, and particularly relates to saccharomyces cerevisiae, a fungicide, application and a screening method. The invention provides a saccharomyces cerevisiae strain DXMC847, which is classified and named as saccharomyces cerevisiae, and is preserved in China Center for Type Culture Collection on November 18, 2024, the preservation address is Wuhan University, Wuhan, China, and the preservation number is CCTCC NO: M 20242592. The saccharomyces cerevisiae strain BY4741 is used as an original strain, and a method of combining ultraviolet mutagenesis with flow sorting is utilized to realize high-throughput screening of acid-resistant strains, so that the acid-resistant strains can be efficiently screened, and the yield of the acid-resistant strains is improved. And finally obtaining the acid-resistant saccharomyces cerevisiae DXMC847. The result of the embodiment shows that the content of pyruvic acid, L-malic acid and succinic acid in the fermentation liquor of the saccharomyces cerevisiae DXMC847 is obviously improved compared with that of the saccharomyces cerevisiae BY4741.
Owner:ZHUCHENG DONGXIAO BIOTECH CO LTD +1

Wormwood planting fertilizer and application thereof

The invention provides a wormwood planting fertilizer and application thereof, and belongs to the technical field of agricultural planting. The wormwood planting fertilizer is prepared from the following components in parts by weight: 10 to 15 parts of humic acid, 5 to 8 parts of amino acid, 2 to 3 parts of wormwood extract A, 3 to 5 parts of wormwood extract B, 15 to 20 parts of nitrogen-phosphorus-potassium compound fertilizer, 0.01 to 0.03 part of sodium selenite, 0.02 to 0.05 part of zinc sulfate, 0.3 to 0.5 part of cellulose nanocrystal, 0.01 to 0.03 part of malic acid and 0.1 to 0.2 part of sodium alginate. By means of the two-dimensional design that components synergistically enhance absorption and the planting process is matched with the growth rhythm, the problems that in traditional fertilization, nutrients are unbalanced, the selenium and zinc utilization rate is low, and pest and disease damage prevention and control are difficult are solved, efficient absorption of wormwood on microelements, accurate supply of nutrients and reduction of the pesticide use amount are achieved, and the yield of the wormwood is increased. The yield and the medicinal quality are synergistically improved.
Owner:LINYI UNIVERSITY

Preparation process of carbon dots for killing helicobacter pylori and application of carbon dots in oral pharmaceutical preparation

The invention relates to the technical field of pharmaceutical preparations, in particular to a preparation process of carbon dots for killing helicobacter pylori and application of the carbon dots in oral pharmaceutical preparations. The preparation method comprises the following steps: mixing microcrystalline cellulose and glycerol, freezing and crushing at an ultralow temperature, and selectively hydrolyzing by combining citric acid-malic acid mixed acid liquor to efficiently prepare a high-crystallinity cellulose nanocrystal template; the controllable synthesis of the carbon dots is realized by utilizing the hydrogen-bond interaction of hydroxyl / carboxyl on the surface of the cellulose nanocrystal and the nitrogen doping effect in the polymerization and carbonization process of citric acid and urea. Besides, when a sodium alginate-chitosan double-layer structure is constructed, carbon dots are introduced into the inner layer to endow the inner layer with special performance, a protein-polysaccharide network is formed on the outer layer through transglutaminase enzymatic crosslinking, and the oxidation resistance and mechanical strength are enhanced through secondary curing of tea polyphenol. According to the invention, food-grade raw materials are used for realizing high-efficiency antibiosis, the oral preparation safety specification is met, and the clinical transformation potential is realized.
Owner:ENYUAN TECH WUXI CO LTD

Zinc-rich cadmium-reducing yield-increasing foliar fertilizer capable of reducing cadmium content of rice as well as preparation method and application method thereof

The invention relates to the technical field of agriculture, in particular to a preparation method and an application method of a zinc-rich cadmium-reducing yield-increasing foliar fertilizer. The specific technical scheme is as follows: the zinc-rich cadmium-reducing yield-increasing foliar fertilizer is prepared from the following components in percentage by mass: 20 to 30 percent of porous chitosan, 30 to 40 percent of L-malic acid and 40 to 50 percent of nano zinc oxide. The technical problem that in the prior art, the zinc content of rice cannot be increased, meanwhile, the rice yield cannot be increased, and the cadmium content of rice cannot be reduced is solved.
Owner:HUNAN AGRI UNIV

Toddalia asiatica twig cutting seedling raising method

ActiveCN120036141ABiocidePlant growth regulatorsToddalia asiaticaLateral root
The invention provides an asiatic toddalia root twig cutting seedling raising method, and relates to the technical field of asiatic toddalia root artificial planting. The Asiatic toddalia root twig cutting seedling raising method mainly comprises the steps of selecting cutting branches, preparing a soaking solution from a 0.05% boric acid solution, IBA and DL-malic acid, treating the upper ends of the cutting branches with an ice-water bath soaking solution, treating the lower ends of the cutting branches with a normal-temperature soaking solution, soaking the cutting branches with quicklime mixed cooked rice milk and the like. According to the method, the defects in the prior art are overcome, the branch cutting rooting rate is effectively increased through treatment of the cutting branches, meanwhile, growth of lateral roots and fibrous roots is promoted, and the quality of Asiatic toddalia root cutting seedlings is improved.
Owner:YUNNAN ACAD OF FORESTRY

Nutraceutical composition for combating aging in human and non-human animals and beverages and / or food products and / or food supplements containing the same

A nutraceutical composition, consisting of Nicotinamide Mononucleotide in a range 250-1000 mg, Spermidine in a range 0.5-10 mg, Rhodiola Rosea in a range 200-600 mg, Cacao in a range 1000-10,000 mg, L-Theanine in a range 50-200 mg, Glucosamine in a range 500-3000 mg, and Hyaluronic acid in a range 50-240 mg, or consisting of Epigallocatechin-3-gallate in a range 100-500 mg, Quercetin in a range 250-1000 mg, Resveratrol in a range 150-1000 mg, Sulforaphane in a range 1-50 mg, and Calcium Alphaketoglutarate in a range 300-2000 mg, or consisting of Microdose Lithium in a range 1-5 mg, Trimethylglycine in a range 500-2000 mg, Glutathione in a range 250-1000 mg, Fisetin in a range 100-1000 mg, Urolithin A in a range 250-2000 mg, Sodium Butyrate in a range 100-3000 mg, Berberine in a range 500-1500 mg, Apigenin in a range 50-500 mg, Cinnamon in a range 1000-6000 mg, and Malate in a range 1000-6000 mg.
Owner:SPIEL DOUGLAS JAY +1

Metal organic framework material as well as preparation method and application thereof

The invention discloses a metal organic framework material as well as a preparation method and application thereof, and belongs to the technical field of chemical separation. The preparation method of the metal organic framework material provided by the invention comprises the following steps: taking water and methanol as solvents, taking 4, 4 '-dipyridyl and malic acid as organic ligands, adding a zinc source, reacting, and in the reaction process, connecting oxygen atoms on the malic acid with zinc ion bonds on the zinc source to form a 2D layered network structure, the two-dimensional layered network structures are bridged through 4, 4 '-dipyridyl to form a 3D rigid network framework, and after the reaction is finished, the metal organic framework material is prepared. The metal organic framework prepared by the invention has a superstrong capture effect and a large storage space on acetylene molecules, and also has an excellent separation effect on an acetylene and carbon dioxide mixed system, so that the aim of purifying acetylene in the acetylene and carbon dioxide mixture at high purity and high yield is achieved.
Owner:NANCHANG UNIV

Aqueous zinc ion battery electrolyte and preparation method and application thereof

The invention relates to an aqueous zinc ion battery electrolyte and a preparation method and application thereof, the aqueous zinc ion battery electrolyte contains soluble zinc salt and an organic additive, and the concentration of the soluble zinc salt in the electrolyte is 1-3 mol / L; and the concentration of the organic additive in the electrolyte is 0.25-3 g / L. Adding the organic additive into the solution containing the zinc salt, and ultrasonically mixing uniformly; the method has the advantages that folic acid, malic acid or chloramphenicol molecules selected as the organic additive can be adsorbed on the surface of the zinc foil, so that the ion flux is uniform, and uniform zinc deposition and stripping are obtained. Water molecules can be effectively prevented from being in direct contact with the surface of the anode, and side reaction and growth of zinc cathode dendrites are inhibited.
Owner:UNIV OF SCI & TECH LIAONING

Method for fractionating lignocellulose biomass by using eutectic solvent and recycling lignocellulose biomass

The invention relates to the technical field of fractionation of lignocellulose biomass, and discloses a method for fractionating lignocellulose biomass by using a eutectic solvent, which comprises the following steps: mixing betaine and malic acid, stirring, and cooling to room temperature after the reaction is finished to obtain a clear and transparent eutectic solvent; the method comprises the following steps: mixing crushed lignocellulose biomass with a deep-eutectic solvent, and putting the mixture into a high-pressure reaction kettle; acetone and n-butyl alcohol are mixed according to the volume ratio of 3: 2-4: 1, and an anti-solvent is prepared; the method comprises the following steps: slowly adding an anti-solvent into a mixture of the lignocellulose biomass and the eutectic solvent, carrying out ultrasonic treatment, and then carrying out suction filtration. The glass electrode pH meter is used for measuring the pH value of the recovered deep-eutectic solvent, and the newly prepared deep-eutectic solvent is added according to the pH value, so that the stability of the solvent performance can be effectively maintained, the deep-eutectic solvent always keeps a good fractionation effect in multiple times of recycling, the utilization rate of the solvent is greatly improved, and the production cost is reduced.
Owner:YILI NORMAL UNIV +1

Liquid treatment agent for harmless treatment of red mud and preparation method of liquid treatment agent

The invention discloses a liquid treatment agent for red mud harmless treatment and a preparation method thereof.The liquid treatment agent comprises a treatment agent A and a treatment agent B. The treatment agent A is formed by mixing hydrochloric acid and sulfuric acid, and the treatment agent B is prepared from malic acid, acetic acid, phthalic acid monoester, a solvent and an adsorbent, the mass fraction of the malic acid is 20%-40%, the mass fraction of the acetic acid is 20%-40%, the mass fraction of the phthalic acid monoester is 15%-25%, the mass fraction of the solvent is 5%-15%, and the mass fraction of the adsorbent is 5%-15%. The red mud is subjected to primary treatment by using the liquid treatment agent A, and then the red mud subjected to primary treatment is treated again by using the liquid treatment agent B, so that the alkalinity of the red mud can be effectively reduced, and various heavy metals, fluorides, radioactive elements and trace toxic elements in the red mud can be effectively removed; the environment pollution caused by the loss of the harmful substances is avoided, so that the innocent treatment of the red mud is realized.
Owner:OCEAN UNIV OF CHINA

Method for preparing hydrogel in double-crosslinking mode and application of hydrogel

The invention discloses a method for preparing hydrogel in a double-crosslinking mode and application of the hydrogel, and belongs to the technical field of hydrogel preparation. The method for preparing the hydrogel in the double-crosslinking mode comprises the following steps: dissolving malic acid and a polyethylene glycol polymer in a solvent to obtain a mixed solution; adding a cellulose polymer into the mixed solution, mixing and drying to obtain a particle material; and carrying out esterification cross-linking reaction on the granular material to obtain the hydrogel. Malic acid and polyethylene glycol polymers are used as cross-linking agents, two cellulose polymers are used as substrates, chemical cross-linking reaction is carried out at a certain temperature to form a loose large network structure, and the hydrogel with high strength, high yield and high swelling degree is obtained.
Owner:JIANGSU TRAUTEC MEDICAL TECH CO LTD

Elastic powder block type cosmetic product and preparation method thereof

The invention discloses an elastic powder block type cosmetic product and a preparation method thereof. The elastic powder block cosmetic product comprises a powder component, an oil phase component, a preservative and an antioxidant, the oil phase component comprises an organic silicon elastomer, an ester composition and silicone oil; wherein the organic silicon elastomer is prepared from a polydimethylsiloxane / vinyl polydimethylsiloxane cross-linked polymer; the ester composition comprises isononyl isononanoate and diisostearyl malate, and the mass ratio of isononyl isononanoate to diisostearyl malate is (2: 1)-(3: 1); the silicone oil comprises polydimethylsiloxane; the mass ratio of the organic silicon elastomer to the ester composition is (1: 11)-(1: 13.5). The elastic powder block type cosmetic product is moderate in viscosity, light and thin in texture and good in ductility, stability and makeup maintaining performance.
Owner:A & H INT COSMETICS CO LTD

External cream for directionally delivering tranexamic acid to epidermal layer and preparation method thereof

The invention discloses external emulsifiable paste for directionally delivering tranexamic acid to an epidermal layer, which is prepared from the following raw materials in percentage by weight: 1-15% of tranexamic acid, 0.5-7% of alpha-arbutin, 0.3-4% of edetate disodium, 1-5% of azone, 1-5% of sodium dodecyl benzene sulfonate and the balance of water. The skin care product is prepared from, by weight, 0.1%-2% of salicylic acid, 1%-10% of glycerin, 2%-15% of propylene glycol, 0.1%-4% of tween-80 or 0.4%-2% of sorbitan oleate, 0.5%-5% of alpha-tocopherol, 0.5%-5% of diisostearyl alcohol malate, 0.5%-6% of soybean phospholipid, 1%-10% of glycerin monostearate, 0.5%-10% of tetradecanol, 0.02%-0.1% of propyl hydroxybenzoate, 1%-10% of stearic acid, 0.5%-6% of stearyl alcohol and the balance water. Meanwhile, the invention also discloses a preparation method, experiments show that the external cream prepared by the invention has strong capacity of delivering tranexamic acid to the epidermal layer and can ensure that the tranexamic acid can be quickly absorbed by cells to take effect, and the defect that tranexamic acid is difficult to pass through skin cuticle obstacles due to strong hydrophilicity is overcome.
Owner:SHANGHAI LIXIN LIANCHUANG BIOPHARMACEUTICAL TECHNOLOGY CO LTD

Method for extracting and separating general flavone crude extract from stems and leaves of Chinese herbaceous peony and application of general flavone crude extract

The invention provides a method for extracting and separating a general flavone crude extract from paeonia lactiflora stems and leaves, which comprises the following steps: adding a choline chloride-malic acid eutectic solvent into paeonia lactiflora stem and leaf powder, soaking, carrying out ultrasonic treatment, carrying out suction filtration to remove solid impurities to obtain a paeonia lactiflora stem and leaf extracting solution, diluting with ultrapure water, carrying out electrodialysis treatment, and drying to obtain the general flavone crude extract. A solid-liquid mixture containing solid residues is obtained in the middle chamber, precipitates are reserved after centrifugation, and the total flavone crude extract is obtained after blow-drying. The invention also provides application of the extracted and separated total flavone crude extract in preparation of medicines, cosmetics or functional foods for antioxidation, anti-inflammation, anti-tumor, cardiovascular protection or / and immunoregulation. The method is high in separation speed, high in separation rate and environment-friendly, flavone loss can be reduced to the maximum extent, and the yield of the total flavone crude extract is 0.27%-0.39%.
Owner:JIAMUSI UNIVERSITY

Composition with insulin resistance reversing component and preparation method thereof

The invention relates to the technical field of insulin resistance reversal, in particular to a composition with an insulin resistance reversal component and a preparation method thereof.The composition comprises quercetin, procyanidine, malic acid, magnesium carbonate, zinc lactate and cereals, fasting blood glucose, fasting insulin and an insulin resistance index can be reduced through synergistic interaction of all the components, and the insulin resistance index can be reduced; according to the traditional Chinese medicine composition, the insulin sensitivity index is improved, and the problems that in the prior art, traditional Chinese medicine compositions are complex in component, effective components capable of reversing insulin resistance and the synergistic mechanism are unclear, and the content of the effective components in the same medicine is inconsistent due to the influence of the growth environment, so that the treatment effect is unpredictable are solved.
Owner:BEIJING DOCTOR LU BEHAVIORAL MEDICINE SCI & TECH RES INST CO LTD

Difunctional ternary supported noble metal catalyst and application thereof

The invention belongs to the technical field of noble metal catalysts, and particularly relates to a bifunctional ternary supported noble metal catalyst for preparing 2-hydroxy-gamma-butyrolactone through malic acid hydrogenation and application. The invention relates to a ternary supported noble metal catalyst, which has two catalytic reaction functions of hydrogenation and lactonization, the active metal of the catalyst has a higher catalytic hydrogenation function, and the molecular sieve provides favorable reaction acidic sites for lactonization. A combination of metals Re, Ru and Pt is used as an active metal component of the catalyst; wherein in percentage by weight, the zeolite molecular sieve accounts for 82-84%, and the active metal accounts for 16-18%. According to the present invention, the high activity and high selectivity noble metal catalyst has high activity and high selectivity under neutral and low temperature conditions, and the hydrogenation and the lactonization reaction are simultaneously performed in the synthesis system by using the bifunctional ternary metal catalyst and using the malic acid as the raw material so as to directly obtain the alpha-hydroxy-gamma-butyrolactone;
Owner:SHENYANG RES INST OF CHEM IND

Negative electrode electrolyte, preparation method thereof and zinc-bromine flow battery

The invention belongs to the technical field of electrochemical energy storage, and provides a negative electrode electrolyte, a preparation method thereof and a zinc-bromine flow battery. The negative electrode electrolyte comprises the following components: zinc bromide, supporting electrolyte, a negative electrode additive and water, and the negative electrode additive comprises malic acid; and the concentrations of the zinc bromide, the supporting electrolyte and the malic acid in the negative electrode electrolyte are 2.0 to 2.5 mol / L, 2.0 to 3.0 mol / L and 0.02 to 0.04 mol / L respectively. Zinc dendrites and hydrogen evolution reaction are effectively inhibited, and cooperative improvement of coulombic efficiency, voltage efficiency and energy efficiency is achieved. Therefore, the malic acid is introduced into the negative electrode electrolyte, so that the zinc dendrite and hydrogen evolution reaction in the zinc-bromine flow battery can be effectively inhibited, and the cooperative improvement of coulombic efficiency, voltage efficiency and energy efficiency is realized.
Owner:XIAN THERMAL POWER RES INST CO LTD +1

Peromoate of xanthomeline, crystal form of xanthomeline and preparation method and application of xanthomeline

The invention relates to the field of medicinal chemistry, in particular to xanthomeline pamoate, which has a structure as shown in a formula I. The malate of the compound as shown in the formula I has excellent effects in at least one aspect of physical stability, solubility, hygroscopicity, biological activity, safety, bioavailability, toxic and side effects and the like. # imgabs0 #
Owner:NANJING MINOVA PHARM CO LTD +1

Composition for loosening bowel to relieve constipation as well as preparation method and application thereof

The invention provides an intestine moistening and bowel relaxing composition as well as a preparation method and application thereof. The intestine moistening and bowel relaxing composition is prepared from the following raw materials in parts by weight: 5 to 10 parts of compound fruit and vegetable fermentation liquor, 2 to 4 parts of compound fruit concentrated juice, 0.01 to 0.02 part of compound probiotic powder, 17 to 27 parts of prebiotics, 0.1 to 0.15 part of DL-malic acid, 0.05 to 0.1 part of citric acid, 0.005 to 0.01 part of sodium citrate, 0.01 to 0.02 part of potassium sorbate and 59 to 65 parts of water. The preparation method comprises the following steps: S1, preparing a mixed solution A; s2, preparing a mixed solution B; s3, preparing a mixed solution C; s4, preparing composite fruit and vegetable fermentation liquor; s5, mixing; and the prepared composition for relaxing bowel can be applied to products for relaxing bowel, and has the effects of cleaning intestinal waste, relaxing bowel and regulating intestinal flora.
Owner:TIANYI FOOD (XUZHOU) CO LTD +1

Preparation technology of bamboo shoot pulp enzymolysis and bamboo shoot composite flavor seasoning eggs

PendingCN121312776AEggs preservationBiotechnologyCellulose
The invention discloses a bamboo shoot pulp enzymolysis and bamboo shoot composite flavor seasoning egg preparation technology, and belongs to the technical field of seasoning egg preparation. The preparation process is used for solving the technical problem that the flavor and taste of the seasoning eggs need to be further improved in the prior art, and comprises the following steps: soaking pretreated eggs in flavor seasoning juice for 10-12 hours, and performing post-treatment to obtain the flavored seasoning eggs. Bamboo cellulose modification and bamboo shoot enzymolysis technologies are combined, the hydrophilicity and flavor carrying performance of cellulose are improved through oxidation reduction and glycerol and malic acid grafting, sauce forms stable colloid, the seepage force is enhanced, enzymolysis bamboo shoot pulp releases small-molecule flavoring substances, natural fresh fragrance is given, and the flavor of the bamboo shoots is improved by being matched with vacuum and long-time impregnation. The seasoned eggs are elastic and moist in taste and rich in flavor, and the overall quality is remarkably improved.
Owner:SICHUAN FENGTAI WUCHU FOOD TECH CO LTD

Pichia kudriavzevii capable of producing L-malic acid at high yield, construction method and application of pichia kudriavzevii

The invention discloses pichia kudriavzevii for high yield of L-malic acid as well as a construction method and application thereof, and belongs to the technical field of biology, the pichia kudriavzevii is named as YM-023 and classified as Pichia kudriavzevii, the preservation number is CGMCC No. 35487, the preservation time is July 31, 2025, and the preservation number is CGMCC No. 35487. The preservation unit is China General Microbiological Culture Collection Center (CGMCC). The method comprises the following steps: starting from an acid-resistant yeast Kudriavzevii pichia pastoris strain YL-000 (the preservation number is CGMCC No.35680), carrying out metabolic engineering transformation to obtain a transformed strain, and ensuring that the transformed strain can realize efficient production of L-malic acid in a fermentation mode of adding a small amount of calcium carbonate neutralizer.
Owner:SHANDONG YUANLI TECH CO LTD +1

Medicinal and edible medicine extract, pharmaceutical composition and preparation method of medicinal and edible medicine extract

The invention discloses a medicinal and edible medicine extract, a medicinal composition and a preparation method thereof, and belongs to the technical field of medicinal and edible traditional Chinese medicines. The medicine extract comprises the following raw materials: hovenia dulcis thunb, lalang grass rhizome, lophatherum gracile, corn stigma, emblic leafflower fruit, medlar and pericarpium citri reticulatae. In addition, the invention also provides a preparation method of the medicine extract, which comprises the following steps: mixing the raw materials in proportion, adding 5-6 times of water, decocting twice, filtering and combining filtrate, and concentrating under reduced pressure until the relative density is 1.1-1.2 to obtain the medicine extract. In addition, the invention further provides a pharmaceutical composition which comprises the pharmaceutical extract, fructo-oligosaccharide liquid, corn oligopeptide powder, a freeze-dried complex microbial inoculant, oyster peptide powder and DL-malic acid. The medicinal extract provided by the invention has the advantages that the liver protection effect is also improved while the alcoholism relieving effect is improved.
Owner:HUBEI LISHIZHEN CUBILOSE GRP PAN HEALTH IND CO LTD