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3012 results about "Ethyl cellulose" patented technology

Ethyl cellulose (or ethylcellulose) is a derivative of cellulose in which some of the hydroxyl groups on the repeating glucose units are converted into ethyl ether groups. The number of ethyl groups can vary depending on the manufacturer.

Sustained Release Dosage Forms For Delivery of Agents to an Oral Cavity of a User

Aspects of the invention include a sustained release dosage form that can be administered to an oral cavity, e.g., the mouth. In certain embodiments, the sustained release dosage form is formulated as a lozenge or gum that may be administered to an oral cavity of a user for the purpose of dissolving over a prolonged period of time and thereby delivering an essential oil component therein. In certain embodiments, the sustained release dosage form includes a beneficial agent and, therefore, not only provides for the prolonged delivery of an essential oil component to an oral cavity, but also provides for the sustained release of a beneficial agent thereto. In certain embodiments, the sustained release dosage form includes a biocompatible, water-insoluble polymer, e.g., ethylcellulose and an essential oil component, which are combined in such a manner so as to produce a dosage form that substantially dissolves over a prolonged period of time when positioned within an aqueous environment, such as an oral cavity of a user. In certain embodiments, the sustained release dosage form may include an additional water soluble agent, such as gum arabic, which may be included so as to further provide the dosage form with a desired dissolution characteristic. In certain embodiments, the dosage form may also include a beneficial agent to be delivered to the mouth. Methods of formulating such dosage forms and administering them to an oral cavity for the treatment of an adverse condition are also provided herein.
Owner:BENNES

Controlled release formulations using intelligent polymers

InactiveUS6893661B1Promote absorptionMaintenance of therapeutically effective blood levelPowder deliveryOrganic active ingredientsSmart polymerWater contact
An extended release dosage composition of pharmaceutically active substances that have a water contact angle (θ) such that cos θ is between +0.9848 and −0.9848 presented as a matrix tablet containing the said pharmaceutically active substances, with/without suitable pharmaceutical excipients in intimate mixture with two groups of intelligent polymers having opposing wettability characteristics, one demonstrating a stronger tendency towards hydrophobicity and the other a stronger tendency towards hydrophilicity, the polymer combination being between the ratios of 1:50 and 50:1 amounts effective to control the release of said pharmaceutically active substances in a mathematically predictable manner, wherein the polymer demonstrating a stronger tendency towards hydrophobicity is not less than 5% wt/wt and preferably between 5-70% wt/wt of the final formulation composition. The intelligent polymers being ethylcellulose (EC) as a more strongly hydrophobic and hydroxyethylcellulose (HEC) and/or hydroxypropyl methylcellulose (HPMC) as more strongly hydrophilic (the ratio of HEC to HPMC being between 1:100 and 100:1). The matrix tablet is optionally coated with an enteric coat, 0-5%-15% wt/wt to prevent the initial burst effect seen in such systems and to impart gastrointestinal tract (GIT) “stealth” characteristics especially in the presence of food.
Owner:VALEANT INT BERMUDA

Slowly-released compound acidifier for poultry and livestock feed, preparation method thereof and feed

The invention discloses a slowly-released compound acidifier for poultry and livestock feed, a preparation method thereof and feed containing the same. The compound acidifier comprises the following compositions in part by weight: 30 to 80 parts of complex organic acid, 15 to 50 parts of supplementary materials and 5 to 20 parts of coating agents. The complex organic acid is citric acid, fumaric acid, malic acid, lactic acid, linoleic acid, crataegolic acid, ursolic acid, chlorogenic acid, glycyrrhizic acid and oleanolic acid, and the supplementary materials are silicon dioxide, hydroxypropyl methylcellulose and ethyl cellulose. The acidifier is scientifically proportioned, has strong efficiency and is long-acting and slow-releasing, nutrients in the feed are free from being damaged, the acidifier has good fluidity and is easy to be uniformly mixed with the feed, the digestive absorption of nutrients can be promoted, the conversion rate of the feed can be improved, the productivity of poultry and livestock can be improved, the time for domestic animals for sale can be effectively shortened, the health of gastrointestinal mucosa of the animals can be protected, the immunologic function of the animals can be strengthened, and diseases can be prevented.
Owner:BEIJING DABEINONG ANIMAL HEALTH TECH +1

Zinc metallic coating

The invention discloses a zinc metal coating layer, the zinc metal coating is characterized in that when being calculated according to the parts by weight, the components of the the zinc metal coating are as follows: 50 parts to 100 parts of polyether silicate ester or polymerized silica acid ester, 50 parts to 100 parts of polyvinyl butyral or ethyl cellulose, 1 part to 20parts of one or a plurality of component (s) among nanometer silicon dioxide, nanometer titanium dioxide, nanometer molybdenum dioxide, or nanometer zinc oxide, 80 parts to 200 parts of zinc powder, 0 to 20 parts of rust preventing agent,, 5 parts to 100 parts of coupling agent, 5 parts to 25 parts of brightening agent, 8 parts to 250 parts of film forming auxiliary agent, 5 parts to 10 parts of wettinh agent, 1 part to 5 parts of surface activating agent, 100 parts to 200 parts of thinning agent, 0.5 part to 3 parts of anti-foaming agent and 0.5 part to 5 parts of anti-scratching agent. The bright metal zinc coating layer related by the invention can be taken as the anti-corrosive oxidation resistant zinc metal coating layer of metal product, particularly the black metal product, which can replace the commonly adopted galvanizing technology. The bright zinc metal coating layer of the invention can very conveniently and effectively paint a zinc metal coating layer the binding of which is firm on the metal product, particularly the black metal product.
Owner:胡仲寅

Water-insoluble medicine sustained-release pellet, sustained-release orally disintegrating tablet thereof and preparation method thereof

The invention discloses a water-insoluble medicine sustained-release pellet, a sustained-release orally disintegrating tablet thereof and a preparation method thereof. The water-insoluble medicine sustained-release pellet comprises a hollow pellet core, a medicine layer, an insulation layer and a sustained-release layer, wherein the sustained-release layer comprises the following ingredients: 54 to 88 percent of sustained-release materials, 2 to 30 percent of antitackiness agents and 1 to 30 percent of pore-foaming agents, wherein the percentage is the mass percentage in the sustained-release layer, wherein the sustained-release materials are one kind or several kinds of materials selected from ethyl acrylate and methyl methacrylate copolymers, polyvinyl acetate and ethyl cellulose. Through regulating the coating combinations and filling auxiliary materials to be pressed into orally disintegrating tablets, the medicine can be slowly released for more than 8 to 13 hours, so the stable blood medicine concentration can be maintained, the side effect is reduced, the medicine taking times can be reduced, and the medicine taking is convenient. The invention conforms to zero-grade release, has the advantages of high final accumulated medicine release amount, high efficacy, strong selectivity, good mouth feeling, simple production steps and high efficiency, and can be applied to large-scale production.
Owner:SHANGHAI INST OF PHARMA IND +1

Controlled release composition

InactiveUS20080254124A1Easy for to follow prescribed regimenConstant of releasePowder deliverySolution deliveryEthyl(hydroxyethyl)celluloseCellulose acetate
A composition for controlled delivery of at least one active substance into an aqueous medium by erosion at a preprogrammed rate of at least one surface of the composition, comprising a matrix comprising the active substance, the matrix being erodible in the aqueous medium in which the composition is to be used, and a coating having at least one opening exposing at least one surface of said matrix, the coating comprising a first cellulose derivative which has thermoplastic properties and which is substantially insoluble in the aqueous medium in which the composition is to be used, and at least one of a second cellulose derivative which is soluble or dispersible in water, a plasticizer, and a filler. The coating is a coating which crumbles and / or erodes upon exposure to the aqueous medium such as a body fluid. The first cellulose derivative may be, e.g., ethylcellulose, cellulose acetate, cellulose propionate or cellulose nitrate, and the second cellulose derivative may be, e.g. methylcellulose, carboxymethylcellulose or salts thereof, cellulose acetate phthalate, microcrystalline cellulose, ethylhydroxyethylcellulose, ethylmethylcellulose, hydroxyethylcellulose, hydroxyethylmethylcellulose, hydroxypropylcellulose, hydroxypropylmethylcellulose, hydroxymethylcellulose or hydroxymethylpropylcellulose.
Owner:EGALET LTD

Method for preparation of electrode slurry

The invention relates to a preparation method of electrode pulp, which comprises the step that binding agent, conductive agent and dissolvent are mixed and agitated evenly. The invention is characterized in that the conductive agent is mixed with the binding agent, electrode active material and the dissolvent in the form of conductive agent dispersion, the conductive agent dispersion includes the conductive agent, conducting dispersing medium, dispersant and stabilizer, the dispersant is chosen from one or more of polyacrylamide, polyvinylpyrrolidone, hydroxy ethyl cellulose, polyacrylic ester, dodecyl polyethylene oxide ester, polycaprolactone and alkyl acid and the stabilizer is chosen from on or more of polyvinylidene fluoride, polyfluortetraethylene, polyacrylamide, polyvinylpyrrolidone, methylol cellulose, droxyethylcellulose and polyacrylic ester. The battery which is prepared by utilizing the method provided by the invention has the advantages that the battery capacity is high, the discharging platform is stable, the circulation is good, and the internal resistance change is little; and simultaneously, the invention overcomes the disadvantages that the using quantity of organic solvent is large, the cost is high and the pollution to the environment is large when the pulp is prepared in the prior art.
Owner:BYD CO LTD

Tea polyphenol liposoluble microcapsules and preparation method thereof

The invention relates to microcapsules and a preparation method thereof, particularly to tea polyphenol liposoluble microcapsules and a preparation method thereof, wherein a core material of the tea polyphenol liposoluble microcapsules comprises tea polyphenol and reduced glutathione, a mass ratio of the tea polyphenol to the reduced glutathione is 95-99:1-5, a wall material of the tea polyphenol liposoluble microcapsules is one or a plurality of materials selected from arabic gum, dextrin, corn syrup, ethyl cellulose, methylcellulose, and hydroxypropyl methylcellulose phthalate, and a mass weight ratio of the core material to the wall material is 1:1-4. The tea polyphenol liposoluble microcapsule preparation method comprises the following steps: respectively preparing a core material emulsion liquid and a wall material solution, adding the core material emulsion liquid to the wall material solution, carrying out high speed stirring, homogenizing, and carrying out spray drying to obtain the tea polyphenol liposoluble microcapsules. The tea polyphenol liposoluble microcapsules have characteristics of fine average particle size and slow tea polyphenol release, such that anti-oxidation and absorption utilization efficiency of the tea polyphenol are substantially improved.
Owner:ZHEJIANG MINGHUANG NATURAL PRODS DEV

Disinfection sterilizing type medical supersonic couplant and method of preparing the same

The invention discloses a disinfection sterilization medical ultrasonic coupling medium with the bactericidal function and used in the ultrasonic detection and treatment of skin and cavitary mucosa and a preparation method of the coupling medium, wherein, the ultrasonic coupling medium comprises propylene glycol, de-ionized water and one viscosity modifier of the hydroxy ethyl cellulose, carbomer and hydroxy propyl cellulose. The coupling medium further comprises a fungicide of 0.05 to 0.15 percent and the constituents of the fungicide are any one of polyhexamethylene biguanide, benzalkonium chloride, benzalkonium bromide, chlorhexidine acetate, trichlorobenzene phenoxy diphenyl ether and nanometer silver or any combination of the olyhexamethylene biguanide, the benzalkonium chloride, the benzalkonium bromide, the chlorhexidine acetate, the trichlorobenzene phenoxy diphenyl etherand, and the nanometer silver; the preparation method used for preparing the ultrasonic coupling medium is as follows: dispersing the hydroxy ethyl cellulose in the propylene glycol, stirring and dispersing the hydroxy ethyl cellulose by adding enough water, heating to 75 to 80 DEG C, preserving the heat for 30 minutes to cool the hydroxy ethyl cellulose and the propylene glycol to 45 DEG C, adding the fungicide to stir and cool the fungicide, the hydroxy ethyl cellulose and the propylene glycol to obtain the filled coupling medium. Tests show that the products of the coupling medium have fast and long sterilization effect and meet the requirements of various related standards.
Owner:广州市一杰医药科技有限公司
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