565 results about "Chlorhexidine Acetate" patented technology

An antiseptic cleaning agent, generally, comprising chlorhexidine acetate and a solvent, such as an alcohol and / or water. The chlorhexidine acetate acts as a highly effective biocide. Additionally, the chlorhexidine acetate allows the cleaning agent to dry without leaving a tacky residue. Where the cleaning agent comprises one or more alcohols, the alcohols may comprise any suitable alcohols, including lower alcohols having from 1 to 6 carbon atoms, such as ethanol and isopropanol. In addition to chlorhexidine acetate, the cleaning agent optionally comprises another non-alcohol biocide, such as triclosan. The cleaning agent can be used in any suitable manner. For instance, the cleaning agent may be impregnated in an absorbent material, such as a towelette, swabstick, or gauze. Additionally, the absorbent material may comprise a positively charged or a non-ionic substance, such as polypropylene or polyester.

Antimicrobial lubricant compositions are disclosed. The antimicrobial lubricant compositions are particularly useful in providing antimicrobial capability to a wide-range of medical devices. The compositions include an oil lubricant. Representative lubricants may include polydimethyl siloxane, trifluoropropyl copolymer polysiloxane, and a copolymer of dimethylsiloxane and trifluoropropylmethylsiloxane. The compositions include rheology modifiers as necessary. The compositions also include antimicrobial agents, which may be selected from a wide array of agents. Representative antimicrobial agents include of aldehydes, anilides, biguanides, bis-phenols, quaternary ammonium compounds, cetyl pyridium chloride, cetrimide, alexidine, chlorhexidine diacetate, benzalkonium chloride, and o-phthalaldehyde.

The invention provides a medicament for treating gynecological inflammation, which comprises the following components in parts by weight: 5 to 30 parts of common cnidium fruit, 4 to 30 parts of golden cypress, 4 to 30 parts of lightyellow sophora root, 5 to 30 parts of sessile stemona root, 0.1 to 2 parts of borneol, 0.1 to 2 parts of menthol, 0.1 to 2 parts of chlorhexidine acetate, and 0.1 to 2 parts of vitamin E. Compared with the prior art, the invention adopts a compound preparation consisting of classical Chinese medicaments and western medicaments, and has the characteristics of quickly killing pathogenic bacteria of western medicaments as well as diminishing inflammation and resisting bacteria of Chinese medicaments. Microbiological experiments and toxicant experiments prove that: the Chinese medicinal preparation has an excellent killing effect on pathogenic bacteria causing gynecological inflammation, such as staphylococcus aureus, candida albicans, escherichia coli and other pathogens, has the effects of treating female pruritus vulvae, has an accurate curative effect, low toxic or side effect, excellent functions of inflammation diminishing, sterilization and itching relieving.

The invention discloses a compound lightyellow sophora root-selinum japenious seed bacteriostatic lotion and a preparation method thereof. The lotion contains an extract of lightyellow sophora root, amur corktree bark and selinum japenious seed, chlorhexidine acetate, a surfactant, ethanol and water, wherein the surfactant is selected from lauryl dimethylamine oxide, Alcohol Ethoxylate (AEO-9), Lauric Acid Ethoxylate (LAE-9) and nonylphenol polyoxyethylene ether (NPE-10); the extract is prepared by performing reflux extraction on 10-25 percent of lightyellow sophora root, 35-45 percent of amur corktree bark and 35-45 percent of selinum japenious seed by taking 50-70 percent by volume of an ethanol aqueous solution as an extraction solvent for 1-3 times, every time for 1-1.5 hours, combining extracting solutions, filtering, recovering a filtrate under reduced pressure in vacuum, and concentrating with ethanol till the relative density is 1.08-1.12; and the using amount of the ethanol aqueous solution is 6-8 times of the total mass of the lightyellow sophora root, amur corktree bark and selinum japenious seed. The compound lotion consisting of Chinese native medicament and western medicament components has the effects of killing parasites to relieve itching, clearing heat, drying dampness and clearing away heat and toxic materials, can play a role in protecting private skin mucosa and preventing bacteria invasion, has low cost, and is suitable for young and middle-aged women.

The invention discloses a disinfection sterilization medical ultrasonic coupling medium with the bactericidal function and used in the ultrasonic detection and treatment of skin and cavitary mucosa and a preparation method of the coupling medium, wherein, the ultrasonic coupling medium comprises propylene glycol, de-ionized water and one viscosity modifier of the hydroxy ethyl cellulose, carbomer and hydroxy propyl cellulose. The coupling medium further comprises a fungicide of 0.05 to 0.15 percent and the constituents of the fungicide are any one of polyhexamethylene biguanide, benzalkonium chloride, benzalkonium bromide, chlorhexidine acetate, trichlorobenzene phenoxy diphenyl ether and nanometer silver or any combination of the olyhexamethylene biguanide, the benzalkonium chloride, the benzalkonium bromide, the chlorhexidine acetate, the trichlorobenzene phenoxy diphenyl etherand, and the nanometer silver; the preparation method used for preparing the ultrasonic coupling medium is as follows: dispersing the hydroxy ethyl cellulose in the propylene glycol, stirring and dispersing the hydroxy ethyl cellulose by adding enough water, heating to 75 to 80 DEG C, preserving the heat for 30 minutes to cool the hydroxy ethyl cellulose and the propylene glycol to 45 DEG C, adding the fungicide to stir and cool the fungicide, the hydroxy ethyl cellulose and the propylene glycol to obtain the filled coupling medium. Tests show that the products of the coupling medium have fast and long sterilization effect and meet the requirements of various related standards.

The present invention provides a synergistic topically applied personal hygiene product comprising 8 to 12% by wt. of Povidone-Iodine complex, 0.5 to 1.0% by wt. of potassium iodide, 1 to 10% by wt. of phosphate, 5 to 15% by wt. chlorhexidine acetate, 5 to 20% by wt. of alcohol, 1 to 5% by wt. of citric acid and the remaining being pharmaceutically acceptable excipients which provides disinfection against commonly known pathogens and prevents transmission of most of the sexually transmitted diseases and a process for preparing the same.

An antiseptic cleaning agent, generally, comprising chlorhexidine acetate and a solvent, such as an alcohol and / or water. The chlorhexidine acetate acts as a highly effective biocide. Additionally, the chlorhexidine acetate allows the cleaning agent to dry without leaving a tacky residue. Where the cleaning agent comprises one or more alcohols, the alcohols may comprise any suitable alcohols, including lower alcohols having from 1 to 6 carbon atoms, such as ethanol and isopropanol. Where the ratio of ethanol to isopropanol may be from between about 1:1000 to about 1000:1. In addition to chlorhexidine acetate, the cleaning agent optionally comprises another non-alcohol biocide, such as triclosan. The cleaning agent can be used in any suitable manner. For instance, the cleaning agent may be impregnated in an absorbent material, such as a towelette, swabstick, or gauze. Additionally, the absorbent material may comprise a positively charged or a non-ionic substance, such as polypropylene or polyester.

The invention relates to a vagina swelling metronidazole clotrimazole suppository which comprises an active component consisting of clotrimazole, metronidazole and chlorhexidine acetate, a fat-soluble matrix and a swelling carrier. The metronidazole clotrimazole is fully swelled, so that a medicine-containing layer can be in full contact with the inner wall of the vagina to prevent medicine liquid from flowing out; the swelling metronidazole clotrimazole suppository is an inner and outer layer swelling suppository; and the active component is mixed with different matrixes to prepare an inner layer and an outer layer, so that double effects of quick release and slow release can be achieved. According to the vagina swelling metronidazole clotrimazole suppository provided by the invention, seven unique leading technologies are adopted; and furthermore, the vagina swelling metronidazole clotrimazole suppository has the beneficial effects of preventing the medicine liquid from flowing out, quickly making a response and preventing secondary infection along with long medicine working time and the like.

The invention discloses a bacteriostatic lotion and a preparation method thereof. The bacteriostatic lotion comprises the following raw materials in parts by weight: 0.8-1.6 parts of chlorhexidine acetate (CA), 1.5-2.5 parts of fructus cnidii extraction liquid, 1.5-2.5 parts of khosam extraction liquid, 1.5-2.5 parts of phellodendron extraction liquid, 4-8 parts of polyoxyl stearate (40) (S-40), 1-5 parts of Poloxamer (P-188), 0.5-1.5 parts of borneol, 0.5-1.5 parts of menthol, 1.5-2.5 parts of eucalyptus oil, 20-30 parts of 95% ethanol, 10-15 parts of polyethenoxy ether (AE09), 2-5 parts of 1% cacao brown, 0.5-1.5 parts of 20% glacial acetic acid solution, 15-25 parts of glycerin and 900-1000 parts of purified water. The bacteriostatic lotion has simple process control, good bacteriostatic and antipruritic effect and low cost.

The invention discloses an externally used preparation for household pet disinsection and sterilization, which employs ketoconazole or / and chlorhexidine acetate as the active constituents, and balancing auxiliary materials. wherein the effective composition of bactericide in the external preparation comprises 0.1-20.0% of ketoconazole and 0.04% of chlorhexidine acetate, the effective composition of pesticide in the external preparation comprises 0.001-20.0-% of natural insecticidal cyhalothrin and balancing additive auxiliary materials, the effective composition of sterilizing complexing agent in the external preparation comprises 0.001-20.0úÑ of natural insecticidal cyhalothrin, 0.04% of chlorhexidine acetate, and 0.1-20.0% of ketoconazole.

In the present disclosure, silver ions, copper ions, quaternary ammonium compounds and cationic drugs such as sulphanilamide, chlorhexidine acetate, etc., used as antibacterial agents are incorporated into fibers, filaments and films through nanoclays. The nanoclays serve as a carrier for the antimicrobial agents and are incorporated into the fiber-forming polymer. In one embodiment, the biocidal metals and organic compounds are incorporated into the clay structure via an ion exchange reaction. Nylon nanocomposite filaments and films based on copper and quaternary ammonium ion modified clays provide 100% antibacterial activity against Gram positive Staphylococcus aureus and Gram negative Escherichia coli bacteria at an optimum clay loading of 0.75% (by weight), and the activity is retained up to 50 washes. The resulting filaments show enhanced mechanical properties such as tensile strength and modulus, and find application in areas of medical textiles like sutures, wound dressings and health & hygiene textiles. In addition, they can be integrated into protective clothing, body garments, sportswear and upholstery.

The invention relates to the technical field of hygiene products, particularly relates to nursing and health care of female privates, and provides a female privates nursing composition and a preparation method and application thereof. The composition comprises, by weight, 12.5-26.5 parts of wetting agents, 15-25 parts of extract of radix sophorae flavescentis, 10-20 parts of extract of cortex phellodendri, 10-15 parts of extract of fructus cnidii, 10-15 parts of extract of herba leonuri, 5 parts of extract of rhizoma curcumae, 5-10 parts of extract of stigma croci;, 1-5 parts of hydrolyzed collagen, 3-5 parts of ethyl alcohol, 0.1-2 part of chlorhexidine acetate, 0.3-1 part of poloxamer, and 0.1-1 part of borneol. Various components of the female privates nursing composition have remarkable synergistic effect and can effectively clean the privates, relieve uncomfortable feelings of the privates, suppress bacterium breeding, repair virginal membrane, relieve itching and deodorize, and even assists in beautifying and compacting after long-term use.

The invention belongs to the technical field of medical equipment and disinfection, particularly relates to skin mucosa medical equipment used for inactivating virus. The medical equipment provided by the invention comprises disinfection components and an attachment material, wherein the disinfection components comprise a composite quaternary ammonium salt, chlorhexidine acetate, o-phthalaldehyde, povidone iodine or other colourless iodine, a synergist, a surfactant, chlorine dioxide, ethanol, a chelant, a stabilizing agent, essence and a pH regulator; the attachment material is selected from a cotton swab, wet tissue, tissue, gauze, a cotton bar, a non-woven fabric and a high polymer material; and the medical equipment comprises a disinfection wiping slice, a disinfection cotton bar, a disinfection package, medical dressing wet tissue, a care solution, a cleaning solution, a dressing, a liquid dressing and a woundplast.

The compound Chlorhexidinum acetate spray is prepared with Chlorhexidinum acetate, borneol, menthol, ethanol, essence and distilled water as material. Daily use and clinical observation shows that the spray may be used widely in treating various skin pruritus caused by different causes, including insect bite, irritability, eczema, etc. The present invention is one kind of safe, reliable, externally applied medicine with determined treating effect and low cost.

The invention discloses a compound solid mouth wash effervescent tablet and a preparation method thereof. The effervescent tablet is prepared from honeysuckle extract, chlorhexidine acetate, mannitol, pregelatinized starch, sodium carboxymethyl starch, lactose, acesulfame, polyethylene glycol, L-cysteine, sodium bicarbonate, menthol, lauryl sodium sulfate, DL-tartaric acid and hydroxypropyl methylcellulose. The preparation method comprises the following steps: grinding and screening each raw material; uniformly mixing according to the proportion; and granulating, drying, grinding, mixing and tabletting. The effervescent tablet contains polyphenols, flavonoids, vitamins, amino acids and other multiple bio-reductive drugs, has the effects of diminishing inflammation and resisting allergy, can be used for effectively relieving development of ulcer, preventing or alleviating gingivitis to achieve the effect of strengthening teeth, can be used for killing dental bacteria, reducing injury of the dental bacteria on teeth and gum, effectively cleaning the oral cavity and reducing halitosis, and can indirectly improve the body immunity if being taken for a long time.

The present invention relates to a sanitary towel antimicrobial and a preparation method thereof, pertaining to the field of daily chemical sanitation, wherein, every 100kg antimicrobial contains 3 to 6kg of chlorhexidine acetate, 3 to 6kg of chlorine-hydroxyl diphenyl ether, 1 to 3kg of mint, 3 to 6kg of borax, 3 to 6kg of camphor, 3 to 6kg of calcined alum, 1 to 3kg of leonurus japonicus, 2 to 5kg of angelica, 1 to 3kg of rhizoma ligustici wallichii, 1 to 3kg of holly, 1 to 3kg of cyperus rotundus, 3 to 6kg of lightyellow sophora root, 3 to 6kg of Chinese mugwort leaf, 3 to 6kg of aloe, 20 to 40kg of infusorial earth and 20 to 40kg of gas-phase silicon dioxide. The present invention can be directly added in the under layer of the net surface of sanitary towel. The sanitary towel added with the antimicrobial has the efficacy of clearing heat and toxin, destroying parasites and relieving itching, regulating emmenia and alleviating pain, being comfortable and eliminating peculiar smell, which can be used for curing and preventing various gynecologic diseases.

The invention provides a disinfectant gellant for gynaecology external use and its preparation method, which relates to a pharmaceutical composition for external use to treat gynaecological vaginitis. The disinfectant gellant for gynaecological external use comprises a gel matrix, a penetration enhancer, a bactericide, a surfactant, essence, ethanol and purified water as balance. Each 1000 ml of the disinfectant gellant for gynaecological external use comprises 10% to 12% of gel matrix, penetration enhancer, bactericide, surfactant, essence, ethanol in proportion. The present invention has the advantages that the composite bactericide is added with the penetration enhancer based on chlorhexidine acetate and metronidazole complex formulation. Natural borneol is taken as the penetration enhancer, thereby the invention has double effects of penetrating promotion and sterilization. The invention has the characteristics of wide spectrum, strong sterilization capability and strong nursing capability, as well as the invention employs the gallant for external use.

A Shuangzuotai suppository is prepared proportionally from metronidazole, mycosporin, chlorhexidine acetate, matrix, cotton suppository saturated by said matrix, and a tubular band made of PVC or PE.

The invention relates to a medicine for treating leukotrichia. The medicine has a medicine trade name of heiEsheng and is characterized by mainly consisting of thirty kinds of Chinese herbal medicine: chlorhexidine acetate, folium ginkgo, cortex lycii radicis, polygonum multiflorum, cacumen biotae, cinnamon, black bean, black sesame, walnut kernel, boxthorn fruit, salvia miltiorrhiza, astragalus mongholicus, eclipta, ligusticum wallichii, angelica sinensis, rhizoma zingiberis, cortex mori radicis, caulis polygoni multiflori, asarum, mulberry, date, tuckahoe, ginseng, rhizoma cyperi (refined), sandalwood, indigo naturalis, Chinese honey locust, red flower, cistanche, gallnut and lucid ganoderma. Compared with the prior art, the medicine has the beneficial effects that: 1) the medicine has the curative effect on the leukotrichia phenomenon caused by dankness, evil deficiency, blood and heat stagnation, qi stagnation, blood stasis and liver and kidney deficiency, and the blood supply insufficiency state of a blood vessel for supplying hair nutrition can be effectively improved; and 2) the medicine is an external preparation, the product is used once every 2 to 3 days, and the medicine can be used for the daily cleaning and maintenance of hair.

Gel for preventing and treating gynecological inflammation is disclosed. Raw materials for preparation active components of the gel are composed of hydroxyethyl cellulose, phellodendron, common cnidium fruit, stemona, matrine, chlorhexidine acetate, menthol and borneol. By combining Chinese herbal medicines and chemical medicines for synergism, the gel has effects of rapidly inhibiting and killing pathogenic microorganisms such as staphylococcus aureus, mold, pseudomonas aeruginosa and the like, and has remarkable curative effects on chronic gynecological inflammations such as cervical erosion, leukorrhea with reddish discharge, trichomonas vaginitis and vaginal fungal infection, etc.

The invention discloses a gynecological medical gel dressing and a preparation method thereof, and aims at providing a gynecological medical gel dressing being remarkable in effect of treating various gynecologic inflammations and capable of quickly repairing disseminated congestion, mucosal injury and superficial ulcer caused by vagina inflammatory diseases and cervical erosion. According to the technical points, the dressing comprises chitosan at a concentration of 1.25 to 2.0% and other auxiliary materials; and the preparation method comprises the following steps of: weighing chitosan and dissolving by 0.5% of lactic acid solution to obtain chitosan liquid; slowly adding carbomer accounting for 1% of the total mass and glycerinum accounting for 10% of the total mass to the chitosan liquid; uniformly stirring; adding chlorhexidine acetate accounting for 0.1% of the total mass; uniformly mixing; adjusting pH (Potential of Hydrogen) to 4.5 to 7.5 through a sodium bicarbonate solution; filtering; removing bubble through vacuum equipment to obtain a semi-finished product; detecting biological indexes and physicochemical indexes the next day; performing split charging through a hose syringe; carrying out sterility test, thus obtaining the finished product after confirmation. The gynecological medical gel dressing and the preparation method thereof belong to the technical field of pharmaceutical preparation.

The invention provides pubes-cleaning disinfection nursing liquid used for the pudendum and the vagina of a human body, which consists of 'chlorhexidine acetate (or chlorhexidine gluconate), borneol and osthole' added with a proper amount of synergist and the balance of distilled water, wherein the pH value is adjusted to be 4 to 5 by a pH balance factor. The product can kill pathogenic bacteria of HIV, neisseria gonorrhoeae, staphylococcus aureus, escherichia coli, candida albicans and the like and other viruses in one minutes so as to block cross infections of various infectious diseases, eliminate smells and relieve itching.

The invention provides a multi-purpose disinfectant, which is mainly applied to skin, surfaces of the wound and mucous membranes, surfaces of common articles and textile, and the like. The disinfectant consists of the following raw materials: single and double chain compound quaternary ammonium salt, chlorhexidine acetat(or chlorhexidine gluconate) and proper amount of synergistic agent and distilled water. The disinfectant can quickly kill enteric bacilli, suppurative bacilli, yeast bacteria, hospital infection common bacteria, and all known common bacteria, and is widely applied to fields in medical treatment, industry, civilian use and the like.

Disclosed is a gynecopathy external use washing lotion and a preparation method thereof. The invention relates to a pharmaceutical composition and a preparation method thereof. The washing lotion contains the following components: Callicarpa nudiflora, senecio, radix sophorae falvescentis, stemona, broom cypress fruit, common cnidium fruit, borneol, chlorhexidine acetate and essence. The preparation method comprises the steps of extraction of the above-mentioned components, alcohol precipitation and preparation. The beneficial effects of the invention are as follows: the washing lotion prepared in the invention has no side effects to human bodies and shows good effects on sterilization and detoxification; a small quantity of safe and effective western medicinal components are used as accessories to the washing lotion, which endows the washing location with characteristics of safety, rapidness and efficiency. The preparation method provided in the invention abandons the conventional process of hot reflux extraction of traditional Chinese medicinal materials and has the advantages of a short preparation time, low energy consumption and high extraction efficiency, and is favorable for protecting environment and saving cost.

The invention discloses antibacterial gel hand cleanser and a preparation method thereof. The preparation method comprises the following steps of adding tea tree oil, chlorhexidine acetate and skin care agents in alcohol substances and dissolving at the temperature of 30-70 DEG C to form alcohol solution; adding surfactant and water soluble vitamin E derivative in deionized water to form aqueous solution; adding carbomer in the deionized water; stirring and standing until the carbomer swells sufficiently and disperses uniformly to form semi-solid gel; mixing the aqueous solution and alcohol solution and slowly adding the mixture in the semi-solid gel; adding pH (potential of hydrogen) regulating agents until the pH value is 6.8-7.4; and stirring for 10-30 minutes by using a high-speed homogenizer under the condition that the rotating speed is 1000-5000rmp to obtain the antibacterial gel hand cleanser. The antibacterial gel hand cleanser contains various antibiotic constituents, has rapid and durable effects, is low in irritation and stability, has good broad-spectrum bactericidal and antibacterial effects, and also has good moisturizing and anti-oxidation effects.

The invention relates to herbal skin anti-bacteria gel containing propolis and a preparation method thereof. The main anti-bacteria active substances are propolis and traditional Chinese medicine extracts, and the gel also contains compound chlorhexidine acetate. The gel disclosed by the invention can effectively inhibit microorganisms such as coliform, canidia albicans and staphylococcus aureus from injecting the skin, so as to play the anti-bacterial and anti-inflammation roles; furthermore, auxiliary ingredients such as gel matrix, a humectant, a PH value regulator, a surfactant and a cosolvent are added, so as to obtain a gel product with steady performance; and such gel is good in moisture retention, effective components thereof are uniformly distributed, and the gel can achieve goodanti-bacterial and anti-inflammation effects by being smeared to the skin surface.

The invention discloses a sterilizing mouthwash for oral cavities. The sterilizing mouthwash is made up of the following components: 0.02-0.2% of chlorhexidine acetate, 0.05-0.1% of chitosan, 2-10% of xylitol, 0.001-0.01% of peppermint oil and the balance of purified water. The mouthwash is capable of drastically killing off the pathogenic bacteria which cause various oral diseases such as anaerobic bacteria, candida albicans, staphyloccocus aureus and streptococcus pyogens, and controlling the pathogenic bacteria to avoid dust; and the mouthwash does not contain alcohol, so that no side effect is caused in the oral cavities and the human bodies.

The invention provides a foam disinfectant for medical use. The foam disinfectant consists of chlorhexidine acetate, glycerol, alcohol, grape seed essential oil, an emulsifier op, betaine cocoate, tocopherol, lavender essential oil and de-ionized water. The invention also provides a preparation method of the disinfectant. The foam disinfectant prepared by the invention is rich in foam amount, and the volume content of foam is 40-46%; when the foam disinfectant is heat-stored at 52-56 DEG C, only 0.5-1.0% of foam is reduced after 14d; the foam disinfectant is good in disinfecting effect, and when the foam disinfectant is used for disinfecting skin of hands of a human body, a killing rate on escherichia coli, staphylococcus aureus and pseudomonas aeruginosa within 30s is 99.999-100%, and a killing rate on candida albicans reaches 99.99-100%; the foam disinfectant is long in antibacterial duration, and compared with disinfection with simple using of alcohol, the effective antibacterial duration of the foam disinfectant is increased by 2.5-3 times; and the disinfection is high in volatilizing speed, and the disinfection, after being smeared to the hands, volatilizes within 5-7s without residue on the hands.

The invention discloses disinfectant wipes. The disinfectant wipes comprises a wipes body, wherein a mixed liquid is dissolved in the wipes body, and is prepared from a humectant, a solubilizer, a disinfectant, a preservative, a flavor enhancer and deionized water; the humectant is one or more of potassium sorbate, xylitol and chloroacetic acid; the solubilizer is one or more of sodium carboxymethyl cellulose, sodium dodecyl sulfate, polyvinylpyrrolidone, dipotassium glycyrrhizinate and benzalkonium bromide; the disinfect is one or more of alcohol, paeonol, chlorhexidine acetate, baicalin, aloe extract and citric acid; the preservative is one or more of methylparaben, ethylparaben, diacetyl acetoacetate, salicylic acid and aluminum silicate; and the flavor enhancer is one or more of vanillin, menthol, hexanal and leaf acetate. The wipes have soft texture, bright surface and fragrant smell, and the storage time of the wipes can be prolonged.