27 results about "Chlorhexidine" patented technology

The invention discloses antibacterial polypeptide and application thereof in preparation of pet shower gel, and belongs to the technical field of antibacterial polypeptide. The antibacterial polypeptide is prepared from the following raw materials in parts by weight: 2 to 5 parts of glycerol, 3 to 5 parts of plant polypeptide, 20 to 40 parts of sorbitol, 1 to 2 parts of sodium carboxymethyl cellulose, 0.5 to 1 part of xanthan gum, 2 to 5 parts of sodium methyl hydroxybenzoate, 0.5 to 1 part of a surfactant, 0.5 to 1 part of chlorhexidine, 0.05 to 0.3 part of triclosan and 100 parts of deionized water. The antibacterial polypeptide prepared by the invention can be applied to the preparation process of pet shower gel, and has good antibacterial performance.

The invention relates to the field of bacteriostatic cream, and particularly discloses skin bacteriostatic cream and a preparation method thereof. The skin antibacterial cream is prepared from the following raw materials in parts by weight: 4 to 6 parts of bran coat extract, 2 to 4 parts of chlorhexidine salt, 2 to 4 parts of rutin extract, 1 to 3 parts of carnosine, 0.5 to 0.8 part of sodium hyaluronate, 0.8 to 1.2 parts of film-forming agent and 5 to 8 parts of purified water. The preparation method comprises the following steps: mixing the film-forming agent and a part of water, and uniformly stirring to obtain a film-forming agent solution; the preparation method comprises the following steps: mixing sodium hyaluronate and water, heating, stirring until the sodium hyaluronate and the water are completely dissolved, adding the cavings extract, the rutin extract, the chlorhexidine salt and the carnosine, stirring until the mixture is uniformly dispersed, heating to 75-85 DEG C, emulsifying for 25-35 minutes, homogenizing, adding a film-forming agent solution into the homogenized emulsion, and stirring, concentrating, degassing and discharging the paste in vacuum to obtain the antibacterial paste. The composition can be used for diminishing inflammation and resisting bacteria of damaged skin, and has the advantages of being high in antibacterial rate and capable of avoiding skin pigmentation.

The present invention relates to the use of N-acetylcysteine to enhance the effect of pyrosulfite of alkali or alkaline earth metal and ascorbic acid in combating pigmentation of tooth surfaces, tooth mucosa, dental prostheses or dental prostheses of patients treated with chlorhexidine, and an oral care product comprising chlorhexidine, at least one pyrosulfite of a base or alkaline earth metal, ascorbic acid, and N-acetylcysteine.

The invention relates to the technical field of antibacterial products, in particular to skin antibacterial liquid. The skin antibacterial liquid is prepared from the following raw materials in parts by mass: akebiaquinata, cortex dictamni, tribulus terrestris, radix sophorae flavescentis, slough, chlorhexidine acetate, sodium benzoate and purified water. The skin antibacterial liquid is a Chinese herbal medicine preparation, does not contain hormones, has the effects of clearing away heat and toxic materials, removing dampness and relieving itching, sterilizing and treating tinea and promoting wound healing, is high in permeability, can eliminate deep skin inflammation, can cure various difficult and miscellaneous diseases of skin, and relieves pains of patients with skin diseases. The ointment has an inhibiting effect on staphylococcus aureus, escherichia coli and candida albicans, and is suitable for acute, subacute and chronic eczema, specific dermatitis, contact dermatitis, insect biting and crawling dermatitis, paronychia, hormone drug sequelae, pompholyx, sweat stain, miliaria, sunburn, burn, frostbite, wound infection, scabies, tinea capitis, tinea pedis, tinea manuum, tinea cruris, tinea corporis and the like.

The integrated catheter system includes a catheter adapter including a catheter and an inlet, where the catheter is configured to be inserted into a patient's vascular system; a needleless connector including a first port, a second port positioned opposite the first port, and a side port positioned between the first port and the second port, where the second port includes a valve member; an intermediate tube extending between the inlet of the catheter adapter and the first port of the needleless connector; and an extension tube extending from the side port of the needleless connector, where the needleless connector includes chlorhexidine.

The invention provides a degradable polylactic acid-based human cell sampling brush wire material and a preparation method thereof, and relates to the technical field of preparation of medical supplies. The degradable polylactic acid-based human cell sampling brush wire material is prepared from the following raw materials: a composite modified material, polyethylene glycol, a plasticizer and an antibacterial agent, the composite modified material is obtained by mixing a product A prepared from polylactic acid and maleic anhydride and a product B prepared from polylactic acid and PBAT and then carrying out ultraviolet treatment, the plasticizer is one of glyceryl triacetate and acetyl tri-n-butyl citrate, and the antibacterial agent is chlorhexidine. The mechanical property of the prepared cell extraction brush wire material is improved while the existing characteristics of polylactic acid are not influenced, the elastic recovery rate is particularly improved, the cell extraction brush wire material has better elasticity and structural stability, and the structural stability and operability are kept when the cell extraction brush wire material is used for sampling positions such as cervix uteri; and the application value in cell extraction operation tools is comprehensively improved.

The invention relates to the technical field of cleaning solutions, in particular to a car washing solution for a car as well as a preparation method and application thereof. Comprising the following components in parts by weight: 4-17 parts of alcohols, 0.75-3 parts of organic acids, 0.05-1 part of glutaraldehyde and 0.25-1 part of chlorhexidine. The components of the vehicle washing liquid are food-grade additives, and the vehicle washing liquid is nontoxic, non-corrosive and non-irritant, is directly used for cleaning the outer surface of a motor vehicle and cleaning and disinfecting the inner part of the motor vehicle, is used for directly cleaning a cloth roof of an open car, has strong descaling and decontamination capability, has efficacy on common dirt of the motor vehicle, and is safe and environment-friendly. The sterilization effect is strong, and the antibacterial activity is long-acting.

Antimicrobial compositions include a therapeutically effective amount of neem oil, extract of the plant Hypericum spp., polyunsaturated fatty acids (PUFAs), carrageenans, and / or chlorhexidine; and (optionally) in combination with one or more pharmaceutically acceptable carriers, additives, and / or diluents. The antimicrobial compositions are effective in treating or preventing upper respiratory tract infections, preferably upper respiratory tract infections caused by human Coronaviruses and are included within methods of treating or preventing infection of the upper respiratory tract of humans by a microbial pathogen.

The utility model relates to the field of respiration detection instruments, in particular to a multifunctional respiration filtering device. The opening end is an oval face mask with a fitting mouth shape, the oval face mask is connected to a first connecting pipe, the first connecting pipe is connected to a filtering device, a filtering film is arranged in the filtering device, the other end of the filtering device is connected to a second connecting pipe, and the second connecting pipe is externally connected with a circular connector at the tail end. The circular interface is used for connecting a lung function instrument or an exhaled air nitric oxide detector, and a titanium dioxide coating and a chlorhexidine layer are arranged on the inner wall of the breathing filtering device. The device can be compatible with lung function and exhaled air nitric oxide detection, and has an antibacterial function.

A solvent system co-dissolves thermoplastic polyurethane and an active pharmaceutical ingredient (API) to form a dip-coating solution. The solvent system provides increased solubility of the API compared to prior art solvent systems which use tetrahydrofuran (THF) as the main solvent. A particularly useful API is chlorhexidine to provide antimicrobial properties. The solvent system includes methanol and 1,3-dioxolane in a ratio of about 10 vol.% to 40 vol.% of methanol in the 1,3-dioxolane. The dip-coating solution may be used to coat medical devices, such as catheters, with a polyurethane coating configured to release an API, such as chlorhexidine. The solvent system can dissolve greater than 55 mg / mL chlorhexidine.

The invention discloses a composition of a medical catheter lubricating hydrophilic coating and a preparation method of the composition, belongs to the technical field of medical materials, and aims to solve the problems of excessive swelling, poor combination stability, short service time, low cost and the like caused by uniform water absorption of a coating formed by curing a medical catheter hydrophilic lubricating coating composition in the prior art. In order to overcome the defects that an existing improvement scheme depends on a complex process, is high in cost and is easy to layer, the invention relates to the technical field of medical instruments, and comprises the following components in percentage by mass: 7-10% of polyvinylpyrrolidone; 1.5 to 2.5 percent of polyethylene glycol diacrylate; 0.8 to 1.2 percent of a silane coupling agent KH-570; the content of the medical grade 2-hydroxy-4-methoxyacetophenone is 0.1 to 0.2 percent; 62-68% of absolute ethyl alcohol; 14 to 18% of deionized water; 0.1 to 0.3 percent of chlorhexidine acetate; and 0.2 to 0.5 percent of citric acid. The composition has the property of spontaneously forming a gradient cross-linked structure, the gradient water absorption characteristic can be achieved under the conditions of conventional coating and single-condition curing, extra precise process control is not needed, the industrialization difficulty and cost are reduced, and meanwhile the problem that the binding force between multiple coatings is poor is solved.

The utility model belongs to the technical field of medical supplies, in particular to a preoperative skin cleaning device which comprises a cleaning device body used for preoperative skin cleaning, the cleaning device body is composed of a brush handle, a sponge brush head, a chock plug, a pressing rod, a pressing head and a protective cover, the sponge brush head is arranged on the brush handle, and the chock plug is arranged on the sponge brush head. A containing groove, a liquid storage cavity, a liquid outlet, a liquid outlet groove and a clamping groove are formed in the brush handle, a plug is contained in the liquid outlet and connected with a pressing head through a pressing rod, a sealing rubber ring is arranged in the brush handle, and 2% chlorhexidine suitable for preoperative skin cleaning and disinfection is stored in the liquid storage cavity. According to the utility model, the hand holding of medical personnel is facilitated, meanwhile, the sponge brush head is used for adsorbing 2% chlorhexidine to clean and disinfect the skin of a patient before an operation, the sponge brush head can be in full contact with the skin of the patient, the 2% chlorhexidine is uniformly released to the surface of the skin of the patient, and the convenience and effectiveness of skin cleaning and disinfection are improved.

The antimicrobial composition comprises a therapeutically effective amount of neem oil, an extract of a Hypericum plant, a polyunsaturated fatty acid (PUFA), carrageenan and / or chlorhexidine; and (optionally) in combination with one or more pharmaceutically acceptable carriers, additives and / or diluents. The antimicrobial composition is effective in treating or preventing upper respiratory tract infections, particularly upper respiratory tract infections caused by human coronaviruses, and the antimicrobial composition is included in a method for treating or preventing microbial pathogens from infecting the human upper respiratory tract.

The invention belongs to the technical field of medicines, and particularly relates to an ointment for treating enuresis, which is prepared from the following components in percentage by weight: 15-20% of fructus psoraleae, 15-25% of fructus alpiniae oxyphyllae, 20-30% of radix linderae, 35-40% of fructus rosae laevigatae and chlorhexidine acetate accounting for 0.1-0.3% of the total mass. The prescription is mainly set for a patient suffering from spleen-kidney deficiency type enuresis, monarch, minister, assistant and guide complement each other, the pharmacological action focuses on two-way regulation of spleen tonifying, kidney warming, gasification and urination reduction, fructus psoraleae and fructus alpiniae oxyphyllae warm kidney and spleen and stop body fluid, lindera aggregata warm kidney yang and dispel cold evil, fructus rosae laevigatae is acerbity and astringent, and can secure spermatorrhea and reduce excretion. According to the formula of the spleen and kidney deficiency type disease, the traditional Chinese medicine has the effects of tonifying qi deficiency of the spleen and kidney, warming the kidney, strengthening qi, transforming water and liquid, strengthening and dredging channels and stopping enuresis.

Methods and compositions are contemplated which may be used to clean an instrument while minimizing the effects of corrosion upon these instruments. The composition may comprise an anticorrosive agent and an antiseptic. The combination of an anticorrosive agent of methylene blue and an antiseptic of chlorhexidine, hydrogen peroxide, povidone iodine, sodium hypochlorite, isopropyl alcohol, citric acid, or combinations thereof has been found to give effectual cleaning results upon contaminated instruments. The compositions and methods may be configured so as to achieve sterilization of the instrument. The compositions may further comprise additional components including an antibiotic, a tracer solution or tracer solutions, an adjuvant, and an indicator component.

The invention relates to the technical field of skin care, and discloses a liquid membrane transdermal metabolism freckle removing method which comprises the following steps: S1, cleaning a face: rubbing and foaming by using a proper amount of a face cleaning product, emphatically cleaning a T region, a forehead, nose wings and a jaw, massaging, and cleaning by using clear water; s2, disinfection: using 75% alcohol or chlorhexidine solution to disinfect the face, especially the spot part, avoiding eyes and mouths, and naturally airing or using a sterile cotton towel to dry; s3, exfoliating: spot-coating a color spot area with an tartaric acid solution, washing after a period of time, then performing short massage with alumina microcrystal powder and essence, cleaning and wiping dry; s4, applying a liquid film on the face, namely applying the essence until absorption, forming the liquid film by using the face cream, and repeating the steps in the morning and evening. By utilizing the osmotic pressure principle, pigment molecules gradually move towards the skin surface under the action of natural osmotic pressure, and accumulation of subcutaneous pigments is reduced, so that intense physical or chemical stimulation is avoided, and sensitivity and discomfort in the freckle removing process are reduced.

A packaged intermittent urinary catheter comprising a single use catheter, a packaging surrounding the catheter, and a fluid reservoir holding a lubricant which, upon rupturing the fluid reservoir, is transferred into the packaging to immerse at least a portion of the catheter in the lubricant to prepare the catheter for use, wherein the lubricant comprises an antimicrobial medium. The invention further provides a method of using a packaged intermittent urinary catheter, and the use of a medium comprising at least one species independently chosen from: hypochlorous acid, at least one hypochlorite salt, chlorine dioxide, at least one chlorhexidine salt, and combinations thereof, as an antimicrobial medium for a single use intermittent urinary catheter.

A crystalline salt of chlorhexidine (CHXD) fluoride having a spherical morphology under Scanning Electron Microscopy (SEM) and comprising a fluoride anion and a cation selected from the group consisting of sodium, ammonium, potassium, or tin, and a process for the preparation of monodisperse crystals of the same. There is provided a pharmaceutical 5 composition, and uses thereof in dentistry and medicine.

The use of PREVORA brand topical dental solution (100 mg / ml chlorhexidine) sold by CHX Technologies, Inc., Toronto, Canada, to treat and / or prevent the advance of both dental decay (caries) and periodontal disease in a simplified method of application in a non-clinical setting. A rapid and simplified treatment with PREVORA comprising the application of PREVORA with a cotton swab, for example, on the surface of the tooth extending down to the gum line was found to produce dramatic reduction in soft tissue inflammation. No cleaning, scaling, or other procedures were required to obtain this effect. Thus, no special equipment or skill is required to administer a PREVORA treatment. This enables a dental professional, medical assistant, nurse, pharmacist, for example, to treat the elderly or disabled where they live. Moreover, the typical chair time for such treatment is 10-15 minutes, or less, and the procedure is pain-free.

The invention relates to a rapid self-condensing hydrogel dressing applied to wound repair and a preparation method of the rapid self-condensing hydrogel dressing. The dressing is prepared from phenylboronic acid grafted oxidized dextran POD, carbonyl dihydrazine modified gelatin Gel-CDH and nanoparticles PAC NPs self-assembled by procyanidine and chlorhexidine acetate. When the dressing disclosed by the invention is in contact with wound exudate, the dressing can be quickly self-crosslinked to form stable hydrogel, and has excellent tissue adhesiveness, self-healing capability and mechanical properties similar to skin. Besides, the hydrogel has broad-spectrum antibacterial activity, strong ROS (reactive oxygen species) removal capacity and high biocompatibility, can promote macrophages to be polarized to M2 phenotype, down-regulate proinflammatory cytokines and enhance anti-inflammatory markers, and has a good market application prospect.

The present invention relates to the use of N-acetyl cysteine to increase the effect of alkali or alkaline earth metal metabisulfite salts and ascorbic acid in counteracting pigmentation of tooth surfaces, dental mucous membranes, dental restorations or dental restorations in patients treated with chlorhexidine, and an oral care product comprising chlorhexidine, at least one metabisulfite salt of an alkali or alkaline earth metal, ascorbic acid, and N-acetyl cysteine.

The utility model relates to an absorbable net-shaped suture line which comprises a suture line body, and the suture line body is of a net-shaped structure and comprises a large number of pores. The suture line body is made of an absorbable material, and the absorbable material is made of one of lactic acid, polyglycolic acid, poly (p-dioxanone), poly (lactic-co-glycolic acid) and polyethylene glycol caprolactone; the suture line body is connected with a suture needle to be used cooperatively. The surface of the suture line body is coated with an antibacterial agent. The antibacterial agent is prepared from one of benzalkonium chloride, cinnamyl aldehyde, chlorhexidine and eugenol. The net-shaped structure of the suture line body is formed by loosely weaving a plurality of strands of filaments after stretching and shaping. The utility model aims to provide the absorbable net-shaped suture line for overcoming the existing defects, and the absorbable net-shaped suture line can disperse tensile force, can enter a human body and can be integrated with tissues.

The invention relates to the technical field of health-care products, in particular to skin-soothing health-care emulsifiable paste and a preparation method thereof.The skin-soothing health-care emulsifiable paste is prepared from tribulus terrestris, radix sophorae flavescentis, mint, Chinese magnoliavine roots, senecio scandens, pine needles, perfoliote knotweed herb and chlorhexidine. The cream is prepared from tribulus terrestris, radix sophorae flavescentis, mint, berberis poiretii schneid, senecio scandens, pine needle, perfoliote knotweed herb, chlorhexidine and the like according to a specific proportion, and has the beneficial effects that the skin-soothing health-care cream is scientific and reasonable in formula, adopts the compatibility principle of monarch, minister, assistant and guide, has a good effect of improving skin problems due to the synergistic effect of the components, and is high in safety; the traditional Chinese medicine composition is suitable for improving sub-health crowds caused by whelks, rash, acne, psoriasis, skin itch, redness, skin pimples, skin keratosis and dryness, hair follicle comedo, facial skin laxity and skin aging, and has the effects of promoting health and caring health by smearing uncomfortable parts with the traditional Chinese medicine composition; the preparation method is simple and feasible, is suitable for large-scale production, and has a wide application prospect.

This invention provides a battlefield wound treatment device for first aid in a battlefield environment, belonging to the field of wound care technology. The device includes a bandage, and further includes: two Velcro straps symmetrically fixed to the outer walls of both ends of the bandage about its central axis; the two Velcro straps can be adhered to each other for quick and secure connection of the two ends of the bandage; a sealing bag detachably connected to the middle section of the bottom wall of the bandage; a drug storage component located inside the sealing bag for temporary storage of chlorhexidine and lidocaine; a pressure bladder fixedly connected to the inner side of the top wall of the sealing bag, its top wall being fixedly connected to the bottom wall of the bandage, and containing distilled water; and an ammonium chloride storage component located on the side wall of the middle section of the pressure bladder for storing ammonium chloride. This design reduces the size of the device, making it lighter and more portable, and enabling wound treatment in a very short time, meeting the needs of rapid rescue in emergency situations.

The present invention relates to an oral care product, such as a mouthwash, periodontal gel or toothpaste containing chlorhexidine and sodium DNA. Said oral care product exhibits an antibacterial action effective against gingivitis, bacterial plaque and periodontitis in combination with a healing and anti-inflammatory action and which, in addition, counteracts oxidative stress so as to limit the appearance and progression of irritations of the oral mucosa, thus promoting their trophism.

The present invention relates to a carbonate-hydroxyapatite functionalized with a germicide, chosen among chlorhexidine and its salts, benzalkonium halides, diisobutyl phenoxyethoxyethyl dimethyl benzyl ammonium halides, alkyl dimethyl ethylbenzyl ammonium halides, cetylpyridinium halides and mixtures thereof.The present invention also relates to cosmetic compositions, such as oral care compositions or skin-care compositions, comprising said functionalized carbonate-hydroxyapatite.

Methods and compositions are contemplated which may be used to clean an instrument while minimizing the effects of corrosion upon these instruments. The composition may comprise an anticorrosive agent and an antiseptic. The combination of an anticorrosive agent of methylene blue and an antiseptic of chlorhexidine, hydrogen peroxide, povidone iodine, sodium hypochlorite, isopropyl alcohol, citric acid, or combinations thereof has been found to give effectual cleaning results upon contaminated instruments. The compositions and methods may be configured so as to achieve sterilization of the instrument. The compositions may further comprise additional components including an antibiotic, a tracer solution or tracer solutions, an adjuvant, and an indicator component.