This invention relates to the field of biomedical materials technology, and discloses a
cerium-doped mesoporous
bioactive glass and its preparation method. The
cerium-doped mesoporous
bioactive glass comprises a SiO₂-CaO-P₂O₅ glass network and
cerium element doped in the glass network; the cerium-doped mesoporous
bioactive glass has an amorphous mesoporous structure. This cerium-doped mesoporous bioactive glass is prepared by employing a
sol-
gel method combined with a water-in-oil self-
assembly strategy. Using hexadecylpyridine
bromide as a template agent,
urea as a slow-release alkali source, and
triethanolamine as a reaction
regulator, a stable
emulsion is constructed in an aqueous
system, followed by the sequential introduction of
silicon,
phosphorus,
calcium, and cerium sources. This successfully achieves in-situ uniform
doping of cerium element in the mesoporous bioactive glass network framework. Furthermore, this method requires no subsequent modification steps, and a multifunctional material with an amorphous mesoporous structure, Ce³⁺ / Ce⁴⁺ mixed valence state, and controllable CeO₂
nanocrystal distribution can be obtained in one step.