14 results about "Isothiocyanic acid" patented technology

To provide a masking agent for unpleasant odors derived from plants, in particular a grassy odor of soybean and an unpleasant odor derived from fats and oils of processed meat products (such as a hexanal odor), a method for masking unpleasant odors using the compound, and a method for producing an oral product in which unpleasant odors are masked.SOLUTION: The present invention provides an unpleasant-odor masking agent for oral products which contains at least one aroma compound selected from the group consisting of E-beta-damascone, S-(2-methyl-3-furyl) ethanethioate, beta-caryophyllene oxide, beta-ionone, 2,5-dihydroxy-1,4-dithiane, methyl anthranilate, S-furfuryl thioformate, 1-isothiocyanate-3-(methylthio)propane, nootkatone, 1,4-dioxacycloheptadecane-5,17-dione, sclareol, and sclareolide.SELECTED DRAWING: None

This application provides a ratiometric fluorescent probe for detecting divalent copper ions, its preparation method, and its application. The ratiometric fluorescent probe comprises fluorescently labeled human serum albumin with isothiocyanate and a dye compound; the fluorescently labeled human serum albumin with isothiocyanate is coated on the surface of the dye compound; the dye compound is a compound with the chemical formula shown in Formula I, II, III, or IV. The ratiometric fluorescent probe provided in this application can be applied to various Cu... 2+ The detection scenario, and can detect Cu 2+ Quantitative detection, on-site rapid testing, and live imaging analysis are performed.

This invention discloses the application of disodium 4,4'-diisothiocyanate-2,2'-stilbene sulfonate in the preparation of drugs for the prevention, delay, and / or treatment of blue light-induced retinal damage. It belongs to the field of biomedical technology. This invention demonstrates for the first time that sodium DIDS can effectively protect photoreceptor cells from blue light damage: at the cellular level, sodium DIDS can restore mitochondrial membrane potential, increase ATP levels, reduce reactive oxygen species accumulation, and inhibit mitochondrial-dependent apoptosis; at the animal level, intravitreal injection of sodium DIDS can improve vision in mice exposed to blue light, restore the amplitude of a-waves and / or b-waves in electroretinograms, and protect the outer segment length and outer nuclear layer thickness of cone cells. Sodium DIDS provides a novel therapeutic strategy for blue light-induced retinal photodamage through multi-target synergistic protection of mitochondrial function.

To provide a masking agent for unpleasant odors derived from plants, in particular a grassy odor of soybean and an unpleasant odor derived from fats and oils of processed meat products (such as a hexanal odor), a method for masking unpleasant odors using the compound, and a method for producing an oral product in which unpleasant odors are masked.SOLUTION: The present invention provides an unpleasant-odor masking agent for oral products which contains at least one aroma compound selected from the group consisting of E-beta-damascone, S-(2-methyl-3-furyl) ethanethioate, beta-caryophyllene oxide, beta-ionone, 2,5-dihydroxy-1,4-dithiane, methyl anthranilate, S-furfuryl thioformate, 1-isothiocyanate-3-(methylthio)propane, nootkatone, 1,4-dioxacycloheptadecane-5,17-dione, sclareol, and sclareolide.SELECTED DRAWING: None

The invention relates to the technical field of synthesis, and provides a method for efficiently and continuously synthesizing 1-isothiocyanate-2-chloro-2-propylene, which comprises the following steps: S1, reacting 2, 3-dichloropropene and a thiocyanate compound in a first-stage reaction kettle to obtain a reaction solution; s2, upwards discharging a water phase of the reaction liquid out of the first-stage reaction kettle, enabling an oil phase of the reaction liquid and undissolved sodium chloride solid to run downwards until the oil phase separated by an oil-solid separator enters a second-stage reaction kettle, and discharging the sodium chloride solid out of the system; s3, carrying out rearrangement reaction on the oil phase in a secondary reaction kettle to obtain a mixed solution; and S4, cooling the mixed solution, adding water, mixing, standing for layering to form a first oil phase and a first water phase, and carrying out reduced pressure rectification on the first oil phase to obtain the 1-isothiocyanate-2-chloro-2-propylene. According to the technical scheme, the problems of tedious reaction steps and low production efficiency of the 1-isothiocyanate-2-chloro-2-propylene in the prior art are solved.

The invention belongs to the technical field of chemistry, and particularly relates to a synthesis method of 1-(3, 5-bis (trifluoromethylphenyl)-3-cyclohexyl thiourea. According to the invention, 1-isothiocyanic acid-3, 5-bis (trifluoromethyl) benzene reacts with cyclohexylamine, a one-step synthesis method is adopted, the method is simple and easy to operate, and the purity and the yield can be effectively improved by utilizing the purification method provided by the invention.

The invention relates to the technical field of organic synthesis, and provides a continuous synthesis method of 1-isothiocyanate-2-chloro-2-propylene, which comprises the following steps: S1, dissolving sodium thiocyanate in a mixed solvent, adding 2, 3-dichloropropene, and carrying out nucleophilic substitution reaction to obtain an oil phase and a saline water phase; s2, the oil phase is subjected to a rearrangement reaction, a 1-isothiocyanate-2-chloro-2-propylene crude product is obtained, rectification is carried out, and 1-isothiocyanate-2-chloro-2-propylene is obtained; s3, after the saline phase is extracted, an organic matter phase and a saline raffinate phase are obtained, an extracting agent in the organic matter phase is recycled to serve as a regeneration extracting agent to be reused in extraction treatment, desalting treatment is conducted on the saline raffinate phase, and a sodium chloride solid is obtained; the mixed solvent is water and polyhydric alcohol. According to the technical scheme, the problem of low yield of the 1-isothiocyanate-2-chloro-2-propylene in the prior art is solved.

The application belongs to the technical field of aqueous zinc ion batteries, and discloses an aqueous zinc ion battery negative electrode coating material, a preparation method and application thereof. A poly-nitrogen-oxygen-sulfur heteroatom ligand capable of coordinating with zinc ions is generated by reacting coumarin hydrazide and benzyl isothiocyanate, and further prepared into a required aqueous zinc ion battery negative electrode coating material LXB@Zn by doping with polyvinylidene fluoride. The synthesized aqueous zinc ion battery negative electrode coating material contains imino, heteroatoms S, O and N, which can inhibit the hydrogen evolution reaction, provide more active sites, inhibit dendrites and inhibit side reactions, thereby effectively improving the cycle stability of the aqueous zinc ion battery. In order to solve the problem of difficult preparation of the aqueous zinc ion battery negative electrode organic coating, the application adopts a simple method of adding a binder to prepare the aqueous zinc ion battery negative electrode organic coating.

The application relates to the technical field of organic synthesis, and particularly relates to a method for electrochemically synthesizing isothiocyanate. The method for electrochemically synthesizing isothiocyanate comprises the following steps: sequentially adding an electrolyte, an electrolytic solvent and a reaction substrate into an electrolytic cell without a diaphragm, inserting an anode and a cathode, stirring, performing reaction under the condition of constant current at normal pressure, and after the reaction is completed, performing organic extraction on the electrolyte, and then separating and purifying isothiocyanate; the potential interval is 0.3-2.0 V; the electrolytic solvent is a halogenated alkane and / or a halogenated alcohol; the reaction substrate is an aromatic derivative with an ethyl group and trimethylsilyl isothiocyanate; the temperature is controlled in the range of 10-40 DEG C; the cathode and the anode are modified by a catalyst, and the catalyst is a bimetallic alloy nanoparticle formed by a carbon-supported noble metal and a transition metal element. The application meets the demand of the reaction mechanism of high-efficiency synthesis of isothiocyanate, and efficiently generates isothiocyanate products.

The present application relates to the technical field of fluorescent probe, in particular to a ratio fluorescent probe and its preparation method and application. The ratio fluorescent probe is prepared from isothiocyanate dye modified semiconductor polymer quantum dots, and has strong fluorescence emission peaks at 530 nm and 581 nm, respectively. The isothiocyanate dye is rhodamine B isothiocyanate, the semiconductor polymer quantum dots are composed of polystyrene maleic anhydride copolymer and poly[(9,9-dioctylfluorenyl-2,7-diyl)-alt-(benzo[2,1,3]thiadiazole-4,8-diyl)], and the particle size of the ratio fluorescent probe is 10-200 nm. The detection limit of the ratio fluorescent probe for tyramine is 1.023 μM, which is lower than the allowable limit of tyramine residue, and meets the detection requirements of freshness and safety of aquatic products. The ratio fluorescent probe can be used for real-time / onsite visual quantitative detection of tyramine, and makes the detection process portable, fast and low-cost.

To provide a masking agent for unpleasant odors derived from plants, in particular a grassy odor of soybean and an unpleasant odor derived from fats and oils of processed meat products (such as a hexanal odor), a method for masking unpleasant odors using the compound, and a method for producing an oral product in which unpleasant odors are masked.SOLUTION: The present invention provides an unpleasant-odor masking agent for oral products which contains at least one aroma compound selected from the group consisting of E-beta-damascone, S-(2-methyl-3-furyl) ethanethioate, beta-caryophyllene oxide, beta-ionone, 2,5-dihydroxy-1,4-dithiane, methyl anthranilate, S-furfuryl thioformate, 1-isothiocyanate-3-(methylthio)propane, nootkatone, 1,4-dioxacycloheptadecane-5,17-dione, sclareol, and sclareolide.SELECTED DRAWING: None

Isothiocyanatoethynylbenzene derivatives of formula Iliquid crystal media comprising the isothiocyanatoethynylbenzene derivatives, and high-frequency components comprising these media, especially microwave components for high-frequency devices, such as devices for shifting the phase of microwaves, tunable filters, tunable metamaterial structures, and electronic beam steering antennas (e.g., phased array antennas), and devices comprising said components. Further, an optical component comprising said liquid-crystalline media, operable in the infrared region of the electromagnetic spectrum, the use of said LC medium in the infrared (IR) region, and devices comprising said optical component.

The invention relates to the technical field of synthesis of 1-isothiocyanic acid-2-chloro-2-propylene, and provides a preparation method of the 1-isothiocyanic acid-2-chloro-2-propylene. The invention relates to a preparation method of 1-isothiocyanate-2-chloro-2-propylene, which comprises the following steps: S1, blending a thiocyanate aqueous solution and 2, 3-dichloropropene in a primary reactor, and carrying out primary reaction and separation to obtain an oil phase and a salt water phase; s2, carrying out secondary reaction on the oil phase in a secondary reactor to obtain a reaction solution; s3, carrying out refining treatment on the reaction liquid, so as to obtain 1-isothiocyanate-2-chloro-2-propylene; during the primary reaction, the temperature is 80-90 DEG C, and the reaction time is 10-20 minutes; and during the secondary reaction, the temperature is 100-105 DEG C, and the reaction time is 1.5-4 hours. According to the technical scheme, the problems of low yield, low purity and low production efficiency during production of the 1-isothiocyanate-2-chloro-2-propylene in the prior art are solved.

The present application relates to the technical field of organic synthesis, in particular to a kind of 3-thio / seleno phosphorylated imidazole derivatives and synthesis method and application thereof, the structure general formula of the 3-thio / seleno phosphorylated imidazole derivative is, R 1 Be aryl or alkyl, X is sulfur element or selenium element, R 2 Be methyl or ethyl etc., R 3 Be ethyl or n-butyl etc.;The synthesis method is to use isothiocyanic acid ester or isoselenocyanate, isocyanate and phosphite as reaction raw material, synthesis by electrochemical oxidation reaction.The synthesis method provided by the present application adopts in the integrated cell without metal and chemical oxidant, constructs 3-thio / seleno phosphorylated imidazole derivative by one-pot three-component cross coupling cyclization, has the advantages of simple operation, raw material is cheap and easy to obtain, high synthesis efficiency, high atom economy, is conducive to large-scale preparation and production;3-thio / seleno phosphorylated imidazole derivative disclosed by the present application has excellent locust control activity and protective effect on wheat seedlings, and does not affect aquatic environment at low concentration, and has good biocompatibility, and can be used for preparing biological pesticide.