521 results about "Hypochlorous acid" patented technology

A dry eye composition containing hypochlorous acid and a demulcent. The demulcent can be polyvinylpyrrolidoe with a molecular weight of 30-50 kDa. The composition can be applied to the surface of the eye with a dropper device or a spray dispenser. Critically, hypochlorous acid is stable in the dry eye composition and maintains its effectiveness at preventing microbial growth.

The invention discloses an anti-drip device for hypochlorous acid disinfectant filling, comprising: a liquid discharge pipe, the liquid discharge pipe comprising a liquid inlet part and a liquid discharge part, the liquid inlet part being used for connecting an external chlorous acid disinfectant supply device, and the liquid discharge part being used for discharging a hypochlorous acid disinfectant; the valve element is arranged in the liquid discharging pipe in a matched mode, and the valve element can block one end of the liquid inlet part; the hollow valve rod is arranged on the valve element, and the hollow valve rod is connected with an external pressure air source through a hose; the driving mechanism is used for driving the hollow valve rod to move; wherein a first control valve is arranged on the hollow valve rod; an air guide groove is formed in the valve element, and the hollow valve rod is communicated with the air guide groove; a plurality of first air guide channels are evenly distributed in the valve element and communicate with the air guide groove. The anti-dripping device is good in anti-dripping effect, and waste of hypochlorous acid disinfectants can be reduced.

The invention discloses a ruthenium and samarium double monatomic doped three-dimensional titanium-based tin antimony nickel electrode and a preparation method and application thereof. The preparation method of the electrode comprises the following steps: (1) pretreating the titanium felt; (2) preparing a sol impregnation liquid; (3) sol coating and drying: dipping the pretreated titanium felt in the prepared sol dipping liquid, fully adsorbing and then drying to form a uniform precursor layer; and (4) roasting treatment is conducted, specifically, the dried titanium felt is placed in a muffle furnace to be roasted, and then the steps of dipping, drying and roasting are repeated till the final ruthenium and samarium double monatomic doped three-dimensional titanium-based tin-antimony-nickel electrode is obtained. In the prepared electrocatalyst, ruthenium and samarium are doped into a tin-antimony-nickel electrode in a monatomic form, the utilization efficiency of ruthenium and samarium atoms is improved, and the electrode is endowed with excellent electrocatalytic activity. The unique three-dimensional structure and double-monatomic doping significantly enhance the electron transfer rate and the reaction kinetic characteristics, so that the electrode shows excellent stability and efficient hypochlorous acid generation ability.

The invention relates to a coumarin-based fluorescent probe as well as a preparation method and application thereof in the aspect of HClO detection, and belongs to the technical field of HClO detection. The invention discloses a coumarin-based fluorescent probe W (O-(3-((2-morpholinyl ethyl) carbamoyl)-2-oxo-2hydrogen-benzopyran-7-yl) dimethyl thiocarbamate) prepared on the basis of an intramolecular charge transfer (ICT) mechanism, and a preparation method of the coumarin-based fluorescent probe W. The novel lysosome targeting fluorescent probe contains coumarin as a fluorophore, a morpholine group as a targeting group and a dimethyl thiocarbamate group as a recognition group, is a novel lysosome targeting fluorescent probe, and has excellent performances of high selectivity, low detection limit, low cytotoxicity, high resolution and the like in the aspect of HClO detection; the method can be used for detecting the content of endogenous and exogenous hypochlorous acid in living cells.

The invention provides a preparation method of an aluminum oxide passivation layer, the aluminum oxide passivation layer and a TBC battery, and relates to the technical field of solar batteries. The preparation method of the aluminum oxide passivation layer comprises the following steps: introducing a mixed gas of chlorine dioxide, hydrogen chloride and hypochlorous acid into the silicon substrate, and carrying out first pretreatment; introducing mixed gas of hydrogen and argon, and carrying out secondary pretreatment; introducing mixed gas of nitrogen, oxygen and water vapor, and carrying out third pretreatment; and after the pretreatment is completed, depositing an aluminum oxide passivation layer on the silicon substrate. According to the preparation method, the problem that in the prior art, aluminum oxide is directly deposited on a silicon substrate after texturing, and the fitting degree of aluminum oxide and the textured surface is poor due to poor uniformity of a natural oxide layer is solved, the passivation performance of the prepared aluminum oxide passivation layer is effectively improved, and therefore the open voltage and the conversion efficiency of a TBC battery prepared from the aluminum oxide passivation layer are remarkably improved.

The utility model discloses a comprehensive treatment device of a circulating cooling water system. The comprehensive treatment device of the circulating cooling water system comprises a cooling circulating water pool, a water pump, a cooling tower, a first electromagnetic frequency mixing scale inhibition device, a side filtration system, an electrochemical water treatment device and a hypochlorous acid sterilization device, the water supply main pipe is matched with the heat exchange device and connected with the cooling tower through the water return main pipe, and the cooling tower is connected with the cooling circulation water pool. The first electromagnetic frequency mixing scale inhibition device is arranged on the water supply main pipe; the bypass filter system, the electrochemical water treatment device and the hypochlorous acid sterilization device are respectively connected with the water return main pipe and the cooling circulating water tank through pipelines. The utility model provides a comprehensive treatment device of a circulating cooling water system, which can ensure the heat exchange efficiency of the circulating cooling water system and realize long-term stable operation on the premise of ensuring that the water quality reaches the standard and greatly reducing chemical agents.

The invention discloses a high-sensitivity ratio-type fluorescent probe for detecting hypochlorous acid as well as a preparation method and application of the high-sensitivity ratio-type fluorescent probe. The N '-(4'-(6, 6-dimethyl-4, 5, 6, 7-tetrahydro-1H-5, 7-bridge methylene indazole-3-yl)-[1, 1 '-biphenyl]-4-methylene) malononitrile prepared by using a natural renewable forest resource beta-pinene derivative nopinone as a raw material can selectively react with hypochlorous acid, and the fluorescent color of the N'-(4 '-(6, 6-dimethyl-4, 5, 6, 7-tetrahydro-1H-5, 7-bridge methylene indazole-3-yl)-[1, 1'-biphenyl]-4-methylene) malononitrile is changed from yellow to cyan, so that the effect of the N '-(4'-(6, 6-dimethyl-4, 5, 6, 7 the maximum fluorescence emission wavelength is changed from 460 nm to 375 nm, and the compound can be used as a specific ratio type fluorescent probe for detecting hypochlorous acid and has a good application prospect.

The present disclosure provides compositions, products, kits and methods for producing on demand hypochlorous acid solutions. The present disclosure provides a stable, dry mix product, kit or package that can be employed by an end-user to easily prepare a hypochlorous acid composition with desired features and functionality.

The invention relates to the technical field of disinfectant generation, in particular to a hypochlorous acid disinfectant generation device based on a jet flow type phase interface reaction method, which comprises a bracket, and further comprises a mixing and pressurizing assembly, a mixing pipe mounted on the bracket, a discharging pipe arranged at one end of the mixing pipe, and a pressurizing pipe arranged at the other end of the mixing pipe, a second liquid adding pipe and a liquid outlet pipe are respectively arranged at the end part of the pressurizing pipe; the adjusting assembly comprises a detection pipe installed above the pressurizing pipe, gas in the liquid outlet pipe is detected through the detection pipe, an adjusting piece is arranged between the detection pipe and the second liquid adding pipe, and the flow speed of liquid in the second liquid adding pipe is adjusted through the adjusting piece according to the gas detected by the detection pipe. The adjusting assembly is arranged at the end of the pressurizing pipe, whether chlorine is generated in the liquid outlet pipe of the pressurizing pipe or not is monitored in real time, when chlorine appears, the liquid inlet amount of raw materials is adjusted in time, meanwhile, the position is cooled, meanwhile, the adjusting and detecting means both adopt power during liquid inlet of the raw materials, and more production cost is saved.

The invention relates to the technical field of organic synthesis, in particular to a preparation method of N, N '-dichloro-1, 4-benzenedicarboxamide, which comprises the following steps: taking terephthalamide as an initial raw material and tert-butyl hypochlorite as a chlorination reagent; the method comprises the following steps: carrying out a chlorination reaction on terephthalamide and tert-butyl hypochlorite in a solvent under the protection of inert gas by controlling the reaction temperature, and after the reaction is finished, carrying out post-treatment to obtain N, N-dichloro-1, 4-phthalimide. The preparation method of the N, N '-dichloro-1, 4-benzenedicarboxamide comprises the following steps: taking terephthalamide and tert-butyl hypochlorite as raw materials, and carrying out one-step reaction to generate a dichloro product. Compared with a traditional N, N '-dichloro-1, 4-benzenedicarboxamide production method, the preparation method has the advantages that the amount of three wastes generated is small, the product yield is high, the product purity is high, the operation is safe and convenient, and the preparation method is more suitable for industrial application.

The invention relates to a fluorescent probe for hypochlorous acid detection and a preparation method and application thereof, the chemical name of the fluorescent probe for hypochlorous acid detection is 5-butyl-10, 10-difluoro-9-(4-(methylthio) phenyl)-5-hydro-4H, 10H-9 lambda 4, 10 lambda 4-benzo [de] [1, 3, 2] oxazaboraza [6, 5-g] isoquinoline-4, 6-diketone, and the structural formula of the fluorescent probe for hypochlorous acid detection is as shown in the following formula I. The invention further discloses a preparation method of the fluorescent probe for hypochlorous acid detection. According to the fluorescent probe for hypochlorous acid detection, N-butyl-3-aldehyde-4-hydroxy-1, 8-naphthalimide and (E)-2-butyl-6-hydroxy-5-(((4-(methylthio) phenyl) imino) methyl)-1H-benzo [de] isoquinoline-1, 3 (2H)-diketone are used as raw materials, and the fluorescent probe can be used for detecting hypochlorous acid. Compared with the prior art, the fluorescent probe for hypochlorous acid detection is simple and convenient in synthesis method, simple and easily available in raw materials, good in hypochlorous acid selectivity, relatively high in sensitivity and large in Stokes shift, and has a very good application prospect in hypochlorous acid detection.

The invention provides a device and a method for purifying culture circulating water in a higher-place pond, and the method specifically comprises the following steps: the culture circulating water and residual feed and excrement in the higher-place pond flow out from a sewage draining exit at the center of the pond bottom, and gradually flow into a self-settling filter well through a water inlet at the bottom of the well; aquaculture circulating water is filtered by an immersion filtering device in the well and overflows out of the well, and residual feed and excrement settle to the bottom of the well and then are discharged through a shrimp shell excrement drain outlet; the breeding circulating water overflowing out of the well flows through a hypochlorous acid oxidation device to be disinfected; the culture circulating water treated by the hypochlorous acid oxidation device flows into an aeration dechlorination tank to remove harmful gas; the culture circulating water treated by the aeration dechlorination tank flows into the ecological tank, so that the contents of carbon, nitrogen, phosphorus and the like in the water are reduced; and the culture circulating water treated by the ecological pond is pumped into the higher-place pond through a reflux pump. The system is efficient, energy-saving, small in occupied area, high in automation degree and capable of improving the water quality management efficiency and stability of higher-place pond culture circulating water.

The invention discloses a donor-receptor porphyrin molecular engineering-based high-sensitivity hypochlorous acid fluorescent probe and a synthesis method thereof, the structural formula of the probe is as follows: # imgabs0 #, the probe can detect hypochlorous acid (HClO) with high sensitivity, phenothiazine groups are introduced at two meso positions of porphyrin, and a donor-receptor (D-A) system is formed in molecules. The probe has rapid response performance to hypochlorous acid, sulfur atoms in phenothiazine are oxidized through hypochlorous acid, phenothiazine electrons are prevented from being transferred to porphyrin under light excitation, and therefore red fluorescence is shown, and selective detection of hypochlorous acid is achieved. After the probe reacts with hypochlorous acid, 667 nm red fluorescence is emitted under the excitation wavelength of 450 nm, the fluorescence appears obviously, and the Stokes shift is 217 nm. The reaction product has the advantages of good water solubility, high fluorescence quantum yield, large Stokes shift and the like. The probe can detect hypochlorous acid with high sensitivity, and has a huge application prospect in the technical fields of analytical chemistry, life science, environment detection, biomedical treatment and the like.

The utility model discloses a hypochlorous acid liquid mixing detection device which comprises a raw material feeding device, a mixing cavity device, a communicating pipeline and a detection cavity assembly, the raw material feeding device comprises a check valve, a straight joint I and a connecting pipe II, and one end of the check valve is fixedly connected with one end of the connecting pipe II. According to the utility model, the detection cavity assembly is independent of the mixing cavity and is connected with the mixing cavity through the slender communicating pipeline, so that a mixed solution can stably and slowly flow into the detection cavity, and the physical isolation of a mixing area and a detection area is realized; the direct impact of turbulent flow, bubbles or concentration fluctuation generated in the mixing process on the detection sensor is effectively avoided, the inlet and the outlet of the detection cavity are both designed to be thin and narrow channels and are located on the upper portion, the standing time of a solution in the detection cavity is prolonged, it is ensured that the detection cavity can be fully and stably filled with the solution, and the detection efficiency is improved. And a stable detection environment is provided for the sensor.

The invention discloses a novel preparation method of basic magnesium hypochlorite and application of the basic magnesium hypochlorite in magnesium-based flame-retardant antibacterial filler. The novel preparation method comprises the following steps: under the assistance of pulsed ultrasound, adding a buffer solution into a sodium hypochlorite solution to adjust the pH value to 9.0-10.5; then adding a magnesium chloride solution for reaction to prepare basic magnesium hypochlorite; intermittent pulses are adopted in the pulse ultrasound, the frequency is 20-40 kHz, and the power density is 100-500 W / L; the pulse ultrasonic technology is introduced, the reaction process can be optimized through the cavitation effect and the micro-mixing effect, the pH distribution of a reaction system is optimized through pulse ultrasound, local overhigh alkalinity is avoided, generation of magnesium hydroxide is inhibited, the particle size of a product can be effectively reduced, and the yield of the product is improved. High-purity basic magnesium hypochlorite (Mg (OH) 2 is less than 1wt%), high available chlorine (greater than or equal to 41%) and narrow particle size distribution (D50lt; and when the flame-retardant antibacterial filler is used as the flame-retardant antibacterial filler, the performance is more excellent.

The invention discloses a difunctional near-infrared fluorescent probe as well as a synthesis method and application thereof. The structural formula of the fluorescent probe is shown as a formula (I). The fluorescent probe DTPD provided by the invention can be used for fluorescent quantitative detection of hypochlorous acid and viscosity, and the fluorescent probe can realize detection of hypochlorous acid with high selectivity in an aqueous solution and is not interfered by other coexisting substances. Besides, the near-infrared fluorescent probe provided by the invention has relatively strong organism penetrability in a near-infrared region, can also reduce the interference of autofluorescence of organisms, and has a good cell imaging effect. And # imgabs0 #.

The invention discloses a PVDF / PFA composite filter material for sewage treatment and a preparation method of the PVDF / PFA composite filter material, and relates to the technical field of water treatment. When the filtering material is prepared, firstly, N-propenylimidazole and 1-chloro-3-phenylpropane react to prepare vinyl imidazolium salt, PVDF subjected to alkali treatment is grafted with the vinyl imidazolium salt, then the PVDF and 5-aza-uracil react, and modified PVDF is obtained; secondly, enabling resorcinol, 3, 5-dihydroxybenzoic acid and formaldehyde to react to obtain porous microspheres, and sulfonating the porous microspheres through chlorosulfonic acid to obtain modified microspheres; finally, PVDF, PFA, polyoxyethylene and the modified microspheres are mixed and subjected to melt spinning, and a fiber membrane is prepared; and carrying out in-situ generation of ferroferric oxide, and activating with hypochlorous acid to obtain the PVDF / PFA composite filter material for sewage treatment. The filter material prepared by the invention has good antibacterial, hydrophilic and photocatalytic degradation properties.

This invention relates to the field of industrial wastewater treatment technology, and discloses an electrocatalytic oxidation device and its operating method for treating saline industrial organic wastewater. Wastewater enters the reaction chamber through the bottom inlet, is forced through the anode channels, and undergoes an electrochemical oxidation reaction on the anode surface to convert chloride ions into hypochlorous acid. A vacuum ultraviolet light source performs in-situ photolysis of water molecules and hypochlorous acid, exciting various active species, including strongly reducing hydrated electrons, strongly oxidizing hydroxyl radicals, and chloride radicals. This device, through the construction of a reduction-oxidation system, can efficiently degrade various pollutants with both electron-rich and electron-deficient characteristics. This invention utilizes the synergistic coupling of electrochemical generation and photochemical conversion to convert high-concentration chloride ions into active precursors, effectively overcoming the bottlenecks of low degradation efficiency and poor selectivity in traditional technologies for high-salt and complex water quality, and significantly improving the system's mineralization efficiency and energy utilization rate.

A space purification device (11) is provided with: a storage unit (13) for storing an aqueous solution (hereinafter referred to as electrolyte (13a)) containing sodium chloride or potassium chloride inside a housing; an electrolysis unit (14) that is provided inside the storage unit (13) and that generates an aqueous hypochlorous acid solution (13b) by electrolyzing the electrolyte solution (13a); an air introduction unit (15) that sucks air from the outside of the housing and introduces the air into the reservoir unit (13); and an air release unit (16) for releasing air in a space (23) above the hypochlorous acid aqueous solution (13b) in the storage unit (13) to the outside of the housing. Furthermore, the electrolysis unit (14) generates an aqueous hypochlorous acid solution (13b) by electrolyzing the electrolyte solution (13a) in a state in which sodium chloride or potassium chloride (hereinafter referred to as electrolyte (13c)) is deposited in the electrolyte solution (13a).

The present invention provides a method for detecting ClO by fluorescence and ultraviolet. ‑ When the anion ClO is added to the pure aqueous solution of PY, ‑ , AcO ‑ ,H2AsO4 ‑ ,Br ‑ ,F ‑ ,Cl ‑ ,ClO4 ‑ ,CN ‑ ,H2PO4 ‑ ,HSO4 ‑ ,N3 ‑ ,NO3 ‑ ,NO2 ‑ ,OH ‑ ,SCN ‑ ,P2O7 2‑ When ClO ‑ It will cause significant quenching of the fluorescence emission spectrum and red shift of the UV absorption spectrum. However, the addition of other anions has no effect on the fluorescence and UV absorption of the phenazine derivative PY solution. It also shows good selectivity and anti-interference ability. At the same time, through fluorescence and UV titration experiments, it was found that ClO ‑ There is a good linear relationship between the concentration and fluorescence intensity, and the minimum fluorescence detection limit is calculated to be 5.59×10 ‑8 The minimum detection limit of M and UV is 5.84×10 ‑7 M. Finally, we made it into a test strip for semi-quantitative detection of ClO ‑ This recognition and detection performance has important application value in the field of ion recognition.

A rubber composition containing a nanocellulose and a rubber component, wherein the nanocellulose contains an oxide of a cellulose raw material by a hypochlorous acid or a salt thereof and is substantially free of a N-oxyl compound. A rubber composition containing a nanocellulose and a rubber component, wherein the nanocellulose has an anion modification group, the rubber component is grafted to the nanocellulose.

Methods and systems for the controlled production of aqueous halogen solutions with varying compositions are disclosed. According to an embodiment, aqueous solutions of hypochlorite ions are modified through the sequential addition of pH adjusting chemicals, non-chloride halide ions, and halogen stabilizing compounds. Sensors, for measuring physical and chemical properties of the solutions as they change due to the impact of the various chemical reactions, are linked to a control system which, in turn, can control the input of one or more chemicals. The control system facilitates the production of a solution with desired characteristics in terms of pH, specific halogen composition, degree of halogen stabilization, and limiting the production of undesired by products such as bromate ions.

The utility model relates to the technical field of integrated hypochlorous acid generators, and discloses an integrated hypochlorous acid generator capable of quickly adjusting pH value, which comprises a production tank support frame, the top surface of the production tank support frame is fixedly connected with a top cover plate, one side of the production tank support frame is internally provided with a salting cleaning assembly, and the other side of the production tank support frame is internally provided with a top cover plate. The bottom of the production tank body supporting frame is provided with a salting discharging assembly, the top surface of the production tank body supporting frame is fixedly connected with an internal adjusting box, the side surface and the bottom surface of the internal adjusting box are provided with PH detection assemblies, and the inner side of the internal adjusting box is provided with a PH adjusting assembly. The salinization cleaning assembly can efficiently clean residual salinization, and interference to production is avoided; the pH detection component and the adjusting component work cooperatively, so that the pH value of hypochlorous acid can be adjusted quickly and accurately, and various scene requirements are met; and the salting discharging assembly is convenient to operate, salting is convenient to discharge, and the equipment performance and the use convenience are integrally improved.

This invention provides a technology to suppress the reduction of the aqueous solution in the electrolytic cell due to evaporation, even when electrolysis is repeatedly performed in a miniaturized air purification device. [Solution] The electrolytic cell 30 stores a first aqueous solution L1 and generates hypochlorous acid from the first aqueous solution L1. The metal ion supply tank 20 stores a second aqueous solution L2 and supplies chloride ions contained in the second aqueous solution to the first aqueous solution L1. The first air passage 60 connects the internal space 12 on the chloride ion supply tank side and the internal space 35 on the electrolytic cell side. The water recovery unit 36 ​​recovers moisture contained in the air flowing from the electrolytic cell 30 as liquid and returns it to the electrolytic cell 30. The space purification device 1 performs a purification operation in which air introduced from the external space R flows through the electrolytic cell 30 and is released into the external space R together with hypochlorous acid. During the purification operation, gas generated in the metal ion supply tank 20 flows through the first air passage 60 and the electrolytic cell 30 and is released into the external space R together with the air.

The invention belongs to the technical field of pollutant treatment, and particularly relates to a Cu < 2 + >-mediated method for degrading neonicotinoid pollutants in a water body, which comprises the following steps: S1, adjusting the initial pH value of the water body containing the neonicotinoid pollutants to 6.0-9.0; s2, adding bivalent copper ions Cu < 2 + > and hypochlorous acid HOCl into the water body, and reacting for 12-48 hours; the concentration of bivalent copper ions Cu < 2 + > is not higher than 1mg / L, and the concentration of hypochlorous acid HOCl is not higher than 10mg Cl2 / L. Compared with the prior art, the induction mechanism of Cu < 2 + > on free radical oxidation of the neonicotinoid pollutants is clarified, the degradation speed and the total degradation rate of the neonicotinoid pollutants are improved by utilizing Cu < 2 + >, the degradation rate of the neonicotinoid pollutants after 6 hours exceeds 60%, and the degradation rate of the neonicotinoid pollutants after 36 hours can reach 99%.

The invention discloses a novel BODIPY-based near-infrared open-type fluorescent probe for detecting hypochlorous acid as well as a preparation method and application of the novel BODIPY-based near-infrared open-type fluorescent probe. The fluorescent probe is (5, 5-difluoro-1, 3, 9-trimethyl-7-(4-sulfur morpholinyl styryl)-5H-dipyrrolo-diazaborolo-penta [10] alkene-10-yl)-4-phenol, which is abbreviated as BOD-Y. The invention also discloses a preparation method of the fluorescent probe. The probe BOD-Y can specifically recognize hypochlorous acid, the color of a probe BOD-Y solution added with hypochlorous acid is rapidly changed from green to blue under sunlight, and the fluorescence is also changed from colorless to strong red fluorescence. The detection limit of the probe on hypochlorous acid is as low as 21nM, the probe shows a good linear relation within 0-35 [mu] M, and the response time is within 13 seconds. The probe shows good selectivity on hypochlorous acid, and is not influenced and interfered by other anions, cations, biological mercaptan, active oxygen and the like.

A rubber composition or the like which contains: nanocellulose that contains an oxide of a cellulose-based starting material obtained using hypochlorous acid or a salt thereof and that does not substantially contain an N-oxygen radical compound; the ratio of the elongation at break value of a rubber formed from the rubber composition to the elongation at break value of a control rubber formed from a control rubber composition in which the nanocellulose is removed from the rubber composition is 0.90 or more and less than 1.15.

This invention discloses a naphthimide-based fluorescent probe for detecting HClO and its preparation method. The fluorescent molecular probe uses naphthimide as the fluorophore and C=N as the specific reaction site for HClO. Due to the presence of the naphthimide fluorophore, the probe molecule exhibits two-photon properties, enabling deep tissue penetration, reducing background noise, and facilitating fluorescence imaging of biological systems. Furthermore, the introduced morpholine group allows for lysosomal targeting, enabling the monitoring of hypochlorous acid concentration levels in lysosomes, making it a valuable tool for early disease diagnosis. In addition, this type of probe molecule is simple to synthesize, operates under mild reaction conditions, exhibits stable optical properties, and has a high synthesis yield. It can detect a wide range of HClO, making it practically valuable in fields such as biochemistry and environmental science.

The invention belongs to the technical field of fluorescent probes and biological detection, and particularly relates to a hypochlorous acid response type near-infrared fluorescent probe for screening Alzheimer's disease antioxidants as well as a preparation method and application of the hypochlorous acid response type near-infrared fluorescent probe. The near-infrared fluorescent probe FP-MT-HClO provided by the invention is subjected to a specific reaction under the action of HClO, generates obvious fluorescence signal enhancement, outputs near-infrared fluorescence signals at about 665 nm, and has the characteristics of quick response, high sensitivity, good selectivity, strong anti-interference capability and the like. An in-vitro screening model used for simulating an inflammatory oxidative stress link related to the Alzheimer's disease is constructed based on the probe, and rapid screening and activity evaluation of candidate antioxidants capable of reducing the HClO level in cells are achieved. The method disclosed by the invention is good in repeatability, is suitable for in-vitro screening of candidates related to inflammatory oxidative stress, and can be used for early evaluation and mechanism research of an oxidative stress process related to Alzheimer's disease.