2481 results about "Pathogenic microorganism" patented technology

The present invention relates to pharmaceutical compositions suitable for the treatment of chronic diseases associated with the presence of abnormal or an abnormal distribution of microflora in the gastrointestinal tract of a mammalian host, which compositions comprise viable non-pathogenic or attenuated pathogenic Clostridia. The compositions further comprise one or more additional viable non-pathogenic or attenuated pathogenic microorganisms selected from the group consisting of Bacteroides, Eubacteria, Fusobacteria, Propionibacteria, Lactobacilli, anaerobic cocci, Ruminococcus, E.Coli, Gemmiger, Desullomonas, Peptostreptococcus, and fungi. The present invention also provides pharmaceutical compositions suitable for the treatment of the same chronic diseases comprising viable non-pathogenic or attenuated pathogenic Escherichia coli, at least one strain of viable non-pathogenic or attenuated pathoenic Bacteroides and at least one strain of viable non-pathogenic or attenuated pathogenic microorganism.

Nanoemulsion compositions with low toxicity that demonstrate broad spectrum inactivation of microorganisms or prevention of diseases are described. The nanoemulsions contain an aqueous phase, an oil phase comprising an oil and an organic solvent, at least one anti-inflammatory agent, and one or more surfactants. Methods of making nanoemulsions and inactivating pathogenic microorganisms are also provided.

The present invention relates to pharmaceutical compositions suitable for the treatment of chronic diseases associated with the presence of abnormal or an abnormal distribution of microflora in the gastrointestinal tract of a mammalian host, which compositions comprise viable non-pathogenic or attenuated pathogenic Clostridia. The compositions further comprise one or more additional viable non-pathogenic or attenuated pathogenic microorganisms selected from the group consisting of Bacteroides, Eubacteria, Fusobacteria, Propionibacteria, Lactobacilli, anaerobic cocci, Ruminococcus, E.Coli, Gemmiger, Desullomonas, Peptostreptococcus, and fungi. The present invention also provides pharmaceutical compositions suitable for the treatment of the same chronic diseases comprising viable non-pathogenic or attenuated pathogenic Escherichia coli, at least one strain of viable non-pathogenic or attenuated pathoenic Bacteroides and at least one strain of viable non-pathogenic or attenuated pathogenic microorganism.

Nanoemulsion compositions with low toxicity that demonstrate broad spectrum inactivation of microorganisms or prevention of diseases are described. The nanoemulsions contain an aqueous phase, an oil phase comprising an oil and an organic solvent, and one or more surfactants. Methods of making nanoemulsions and inactivating pathogenic microorganisms are also provided.

Nanoemulsion compositions with low toxicity that demonstrate broad spectrum inactivation of microorganisms or prevention of diseases are described. The nanoemulsions contain an aqueous phase, an oil phase comprising an oil and an organic solvent, and one or more surfactants. Methods of making nanoemulsions and inactivating pathogenic microorganisms are also provided.

The present disclosure provides embodiments of a method for characterizing microbial populations. Exemplified by methods for characterizing microbiota in vaginal samples, the methods provided herein are widely applicable to the characterization of microbial communities. Also provided are probiotic regimens and methods for selecting appropriate probiotic regimens based on the normal vaginal microbiota of a subject. Reagents and kits for detecting normal vaginal microbiota and diagnosing pathogenic microorganisms in the vagina are also provided.

The invention provides a method for automatically washing, disinfecting and / or sterilizing health care equipment and / or cooking and catering utensils. The method includes the steps of placing the equipment to be washed in an enclosure; introducing a first electrochemically activated aqueous solution into the enclosure; and either sequentially or simultaneously introducing a second electrochemically activated aqueous solution into the enclosure. The first solution is characterised therein that it has dispersing or surfactant characteristics for at least partially dispersing a biofilm, pathogenic microorganisms, contamination or the like. The second solution is characterised therein that it has biocidal characteristics for killing microorganisms and disinfecting and / or sterilizing the equipment. The invention also extends to an apparatus for use in the above method.

The present invention is a composition of recombinant virus which has incorporated into its genome or portion thereof a gene encoding an antigen to a disease causing agent and a recombinant virus which has incorporated into its genome or portion thereof a gene encoding an immunostimulatory molecule(s) for the purpose of stimulating an immune response against the disease causing agent. Methods of treatment of diseases such as cancer and diseases caused by pathogenic microorganisms is provide using the composition.

Antimicrobial compounds from Bacillus subtilis for use against animal and human pathogens. A novel strain of Bacillus subtilis was isolated from the gastrointestinal tract of poultry and was found to produce a factor or factors that have excellent inhibitory effects on Clostridium perfringens, Clostridium difficile, Campylobacter jejuni, Campylobacter coli, and Streptococcus pneumoniae. The factor(s) retain full viability and antimicrobial activity after heat treatment. The invention provides a method of treatment of pathogenic microorganisms including C. perfringens.

The invention discloses a fluorescent microsphere immunity-chromatography test strip for detecting food-borne pathogenic microorganisms in a rapid, specific, qualitative and quantitative manner and a preparation method thereof. Filter paper, a sample pad, a glass fiber membrane spray-painted by fluorescent microsphere marked food-borne pathogenic microorganism monoclonal antibodies or polyclonal antibodies, a nitrocellulose membrane and drinking paper are stuck to an underplate orderly in a related joint manner; the food-borne pathogenic microorganism monoclonal antibodies or the polyclonal antibodies are coated on the nitrocellulose membrane and are used as a detection area; and anti-mouse antibodies are coated on the nitrocellulose membrane and used as a quality control area. The test strip has the preparation steps as follows: (1) samples to be detected are processed; (2) the nitrocellulose membrane is prepared; (3) a fluorescent microsphere pad is prepared; (4) the test strip is assembled; and during the detection process, the CCD scanning technique is utilized to collect all emission spectrums, and then the emission spectrums are analyzed through a fluorescence analyzer and relevant software after accumulation and multiplication, so that the quantitative detection is realized. The fluorescent microsphere immunity-chromatography test strip and the preparation method thereof are mainly used for qualitative and quantitative detection of all the food-borne pathogenic microorganisms in food safety inspection.

Pathogenic microorganisms are detected in a wide field of view and classified by Raman light scattered light from these organisms together with digital pattern recognition of their spectral patterns.

The present invention relates to a devices and methods for killing and / or debilitating pathogenic microorganisms in or on a patient's body, such as light-sensitive bacteria including helicobacter pylori and / or propionibacterium acnes. A chemiluminescent light source provides electromagnetic radiation having predetermined wavelengths in the visible spectrum. The light wavelengths are selected for absorption by naturally-occurring photosensitive chemicals produced by the patient's body.

Food products, such as precooked meats, sausages, and the like are microbially decontaminated in their cooking packages to remove surface microorganism contamination from the packages. The cooking packages are removed and the food products optionally subjected to further processing, such as slicing, and then packaged in aseptic packaging. The microbial decontamination step, further processing and packaging are carried out in a clean room which is maintained to a high level of sterilization or disinfection to minimize or eliminate contamination of the food products with pathogenic microorganisms such as Listeria Monocytogenes. The food products thus leave the packaging plant with a much higher assurance of food safety than is found in a conventional packaging plant.

The present invention provides biological fertilizer compositions that comprise yeast cells and garbage. The yeast cells of the invention have an enhanced ability to fix atmospheric nitrogen, decompose phosphorus minerals and compounds, decompose potassium minerals and compounds, decompose complex carbon compounds, overproduce growth factors, overproduce ATP, decompose undesirable chemicals, suppress growth of pathogenic microorganisms, or reduce undesirable odor. The biological fertilizer composition of the invention can replace mineral fertilizers in supplying nitrogen, phosphorus, and potassium to crop plants. Methods of manufacturing biological fertilizer compositions, and methods of uses are also encompassed.

The invention discloses an organic fertilizer fermented by chicken manure and a production method of the organic fertilizer, which belong to the technical field of culture waste treatment and biological fertilizer manufacture. According to the invention, the organic fertilizer is prepared and produced by the steps of aerobic curing and anaerobic fermentation, so that the problems of pollution and root burning caused by the chicken manure directly applied to fields are solved, and the innocent treatment and resource utilization of the chicken manure and padding are realized. The final product mainly comprise beneficial bacteria and metabolites of the beneficial bacteria, which have the characteristics that the fertility is durable, the macroecology of the soil can be improved to inhibit pest and disease damage, the soil structure can be improved to improve breathability and the development of the root systems of plants can be enhanced. The purpose of the aerobic curing is to inhibit the growth of infectious microbes, control metabolism direction, kill pathogenic microorganisms, adult parasite, parasite eggs and thermolabile infectious microbes by biological heat and provide a matrix for anaerobic fermentation by decomposing, transforming and synthesizing the microorganisms into thallus ingredients and small molecular substances; and the purpose of the anaerobic fermentation is to augment the beneficial bacteria and generate the metabolites such as organic acid.

The present invention relates to a method for producing fermented edible plants or edible animal / plants, to fermented edible plants or edible animal / plants produced by same, and to foods containing same. The method for producing fermented edible plants or edible animal / plants includes the steps of: producing crushed edible plants or edible animal / plants; culturing a liquid mixture of grains, saccharides, filamentous fungi, and yeast for 24 to 36 hours to produce a mixed microbial broth; inoculating the edible plants or edible animal / plants with the mixed microbial broth, and firstly fermenting the edible plants or edible animal / plants for 3 to 8 days to produce first fermented edible plants or edible animal / plants; and inoculating the first fermented edible plants or edible animal / plants with bacteria, and secondly fermenting the first fermented edible plants or edible animal / plants for 6 to 12 days to produce second fermented edible plants or edible animal / plants. Whereby, a fermentation period can be shortened, and food deterioration and the growth of pathogenic microorganisms can be suppressed. Further, adding the fermented edible plants or edible animal / plants produced by the above-described method into foods can provide storage stability, increase bioavailability, and improve flavor.

The present invention provides biological fertilizer compositions that comprise yeast cells and poultry manure. The yeast cells of the invention have an enhanced ability to fix atmospheric nitrogen, decompose phosphorus minerals and compounds, decompose potassium minerals and compounds, decompose complex carbon compounds, overproduce growth factors, overproduce ATP, decompose undesirable chemicals, suppress growth of pathogenic microorganisms, or reduce undesirable odor. The biological fertilizer composition of the invention can replace mineral fertilizers in supplying nitrogen, phosphorus, and potassium to crop plants. Methods of manufacturing biological fertilizer compositions, and methods of uses are also encompassed.

Pathogenic microorganisms are detected and classified by spectral imaging of the Raman light scattered by the organisms.

The present invention provides biological fertilizer compositions that comprise yeast cells and cattle manure. The yeast cells of the invention have an enhanced ability to fix atmospheric nitrogen, decompose phosphorus minerals and compounds, decompose potassium minerals and compounds, decompose complex carbon compounds, overproduce growth factors, overproduce ATP, decompose undesirable chemicals, suppress growth of pathogenic microorganisms, or reduce undesirable odor. The biological fertilizer composition of the invention can replace mineral fertilizers in supplying nitrogen, phosphorus, and potassium to crop plants. Methods of manufacturing biological fertilizer compositions, and methods of uses are also encompassed.

Pathogenic microorganisms are detected in a wide field of view and classified by Raman light scattered light from these organisms together with digital pattern recognition of their spectral patterns.

The present invention relates to a method for extracorporeal removal of a pathogenic microbe, an inflammatory cell or an inflammatory protein from mammalian blood / use of a device comprising a carbohydrate immobilized on a solid substrate, said carbohydrate having a binding affinity for a pathogenic microbe, an inflammatory cell or an inflammatory protein, for extracorporeal removal of said pathogenic microbe, inflammatory cell or inflammatory protein from mammalian blood / use of a carbohydrate having a binding affinity for a pathogenic microbe, an inflammatory cell or an inflammatory protein, wherein said carbohydrate is immobilized on a solid substrate, in the preparation of a device for treatment of a condition caused or aggravated by said pathogenic microbe, inflammatory cell or inflammatory protein / and a method for treatment of a mammalian subject suffering from a condition caused or aggravated by a pathogenic microbe, an inflammatory cell or an inflammatory protein.

The present invention provides biological fertilizer compositions that comprise yeast cells and sludge. The yeast cells of the invention have an enhanced ability to fix atmospheric nitrogen, decompose phosphorus minerals and compounds, decompose potassium minerals and compounds, decompose complex carbon compounds, overproduce growth factors, overproduce ATP, decompose undesirable chemicals, suppress growth of pathogenic microorganisms, or reduce undesirable odor. The biological fertilizer composition of the invention can replace mineral fertilizers in supplying nitrogen, phosphorus, and potassium to crop plants. Methods of manufacturing biological fertilizer compositions, and methods of uses are also encompassed.

The invention provides feed for improving growth performances of broiler chickens. The feed comprises a main feed ingredient, bone meal, rapeseed meal, monocalcium phosphate, vitamin E, vitamin K, pantothenic acid, lysine, methionine, threonine, sodium butanoate, enzyme additives, probiotics additives, microelement additives and Chinese medicinal herb additives. The feed can well solve the problem that the feed digestion capability of the broiler chickens is poor, effectively controls pathogenic microorganisms, promotes digestion and immunity of the broiler chickens in the growing process, improves growth performances of the broiler chickens, reduces morbidity and mortality of the broiler chickens and reduces medicine residue rate of antibiotics and chemical synthesis medicines in the broiler chickens.

The invention relates generally to antimicrobial compositions that are non-toxic to mammals and plants, and are highly effective against a broad spectrum of detrimental pathogenic microorganisms. The antimicrobial compositions contain at least one zinc compound that is microbicidal to at least one microorganism. The antimicrobial compositions of the invention can be diluted in suitable proportions into suitable solvents to produce the desired dosages for each individual application. The antimicrobial compositions can be applied by conventional methods, e.g., spraying, soaking, fogging, impregnation, and the like. The compositions can also be used as preservatives. The antimicrobial compositions can also be made as gels or solids in different forms by using techniques available to those skilled in the art.

A method and apparatus for treating gum disease includes a light producing dental appliance that is accessible exteriorly of the body for placement within the mouth of the patient to expose the mouth to light radiation of a selected wavelength and in an amount that is effective for killing or debilitating pathogenic microorganisms and especially Porphyromona gingivalis within the mouth of the patient such that the bacterial load carried to the heart is diminished thereby reducing or eliminating the symptoms of coronary artery disease, atherosclerosis vascular inflammation and plaque formation.

Heterocyclic and acyclic silane monomers and siloxane polymers, and their halogenated derivatives, are provided for the purpose of functionalizing surfaces or materials so as to render them biocidal upon exposure to oxidative halogen solutions. The biocidal function can be imparted either before or after bonding or adhesion to the surface or material. The biocidal surfaces and materials can then be used to inactivate pathogenic microorganisms such as bacteria, fungi, and yeasts, as well as virus particles, which can cause infectious diseases, and those microorganisms which cause noxious odors and unpleasant coloring such as mildew. Examples of surfaces and materials which can be rendered biocidal in this invention include, but are not limited to, cellulose, chitin, chitosan, synthetic fibers, glass, ceramics, plastics, rubber, cement grout, latex caulk, porcelain, acrylic films, vinyl, polyurethanes, silicon tubing, marble, metals, metal oxides, and silica.

The invention belongs to the technical field of water treatment and particularly relates to a method and a system for advanced treatment of centralized rural domestic sewage. The treatment system comprises a hydrolytic acidification tank, a composite tower type ecological filter and a surface flow artificial wetland system. The treatment method comprises the following steps of: collecting sewage through a pipe network, allowing the sewage to enter the hydrolytic acidification tank which is a landfill tank, stabilizing and regulating the water quantity, and pumping the sewage into a high-position service reservoir by using a submersible electric pump with the head of more than 5m; distributing the domestic sewage of the hydrolytic acidification tank into the composite tower type ecological filter by strengthening water distribution measures, and removing organic pollutants, total nitrogen, ammonia nitrogen, total phosphorus and pathogenic microorganisms in the sewage; and allowing tail water and collected rainfall runoff to enter the artificial wetland system for advanced treatment. A good water environment landscape can be built for an artificial wetland; and the effluent reaches the first-grade A standard of discharge standard of pollutants for municipal wastewater treatment plant (GB18918-2002).

Improved molecular vaccines comprise nucleic acid vectors that encode a fusion polypeptide that includes polypeptide or peptide physically linked to an antigen. The linked polypeptide is one that (a) promotes processing of the expressed fusion polypeptide via the MHC class I pathway and / or (b) promotes development or activity of antigen presenting cells, primarily dendritic cells. These vaccines employ one of several types of nucleic acid vectors, each with its own relative advantages: naked DNA plasmids, self-replicating RNA replicons and suicidal DNA-based on viral RNA replicons. Administration of such a vaccine results in enhance immune responses, primarily those mediated by CD8+ cytotoxic T lymphocytes, directed against the immunizing antigen part of the fusion polypeptide. Such vaccines are useful against tumor antigens, viral antigens and antigens of other pathogenic microorganisms and can be used in the prevention or treatment of diseases that include cancer and infections.