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69 results about "Extracorporeal" patented technology

An extracorporeal is a medical procedure which is performed outside the body.

Extracorporeal membrane lung oxygenation VR training system

The invention discloses an extracorporeal membrane oxygenation VR training system, which comprises a virtual scene construction module, and is characterized in that the virtual scene construction module carries out modeling on an operating room environment and ECMO equipment based on modeling software; the VR virtual interaction operation module performs virtual scene interaction between the trainee and the virtual scene and the virtual device through the interaction device; the ECMO pre-flushing operation process module generates standard steps and specification requirements based on the construction of the virtual scene and the interaction information of the VR virtual interaction operation module; the multi-person cooperation module is used for distributing persons participating in training according to different roles and playing different persons in a virtual scene for cooperative training; the training content management module is used for managing the ECMO training content of trainees; organic combination of practical training and cyclic training can be achieved, the situation that current ECMO professional medical talents are in shortage is effectively improved, and then the treatment success rate and the medical service quality of critical patients are improved.
Owner:SUZHOU DEJIE WEI DIGITAL TECH CO LTD

Bigeminal carotid artery balloon blocking catheter

The utility model relates to a bigeminal carotid artery balloon blocking catheter, and belongs to the technical field of surgical instruments and equipment. The bigeminal carotid artery balloon blocking catheter comprises a circulation tube and a balloon hose, wherein the circulation tube is of an integrated structure and comprises a main tube, a branch tube and a switch valve; one end of the main pipe is connected with two groups of branch pipes; one end of the branch pipe is connected with an adapter through a switch valve; and a balloon hose is inserted into the adapter. The bigeminal carotid artery balloon blocking catheter is compact in structure and ingenious in design, blood transfusion can be conducted on the left carotid artery and the right carotid artery at the same time under the cooperation of an extracorporeal circulation machine, meanwhile, the blocking function is achieved, the problems that an existing A-type aortic dissection operation is inconvenient to operate and high in risk, and medical resources are wasted are solved, and the bigeminal carotid artery balloon blocking catheter is particularly suitable for being used in the A-type aortic dissection operation.
Owner:HUBEI KANGMENG MEDICAL TECHNOLOGY CO LTD

Modular medical fluid management assemblies, machines and methods

A medical fluid management assembly includes a pneumatic manifold, at least one valve, and a fluid manifold. The pneumatic manifold includes at least one pneumatic passageway that is pneumatically connected to the at least one valve. The fluid manifold includes at least one chamber comprising upper and lower fluid chambers separated by a flexible membrane. The fluid manifold also includes fluid tube sections and fluid pathways that fluidly couple the one or more upper and lower fluid chambers to the at least one valve and at least one of a purified water line, a liquid concentrate line, a to-extracorporeal circuit fresh dialysis fluid line, a drain line, or a from-extracorporeal circuit used dialysis fluid line.
Owner:BAXTER INT INC +1

Emergency treatment in-vitro cooling device

The utility model discloses an emergency treatment in-vitro cooling device, which belongs to the technical field of in-vitro cooling, and comprises a bottom plate, a groove is formed in the top of the bottom plate, bearings are fixedly connected to the opposite inner walls of the groove, rotating shafts are rotatably connected to the interiors of the two bearings, the opposite ends of the two rotating shafts are fixedly connected with the same screw rod, and the same screw rod is fixedly connected with the screw rod. The surface of the lead screw is in threaded connection with a threaded block, the top of the threaded block is fixedly connected with a connecting plate, the top of the connecting plate is fixedly connected with two sets of air cylinders, and the two sets of air cylinders are internally provided with blowing fans. And through operation of the blowing fan, the body of the patient can be cooled, and through operation of an electric push rod, the height of a frame plate can be adjusted.
Owner:THE 985TH HOSPITAL OF THE CHINESE PEOPLES LIBERATION ARMY JOINT LOGISTICS SUPPORT FORCE

Hemodiafiltration system with disposable pumping unit

A hemodiafiltration system with a disposable pumping unit is disclosed. An example system includes a medical fluid pump actuator, a medical fluid heater, a blood filter and a disposable unit. The example disposable unit includes a medical fluid cassette portion including a medical fluid cassette housing configured to be operatively connected to the medical fluid pump actuator to pump medical fluid through the medical fluid cassette portion when the medical fluid cassette portion is in fluid communication with a medical fluid source. The example medical fluid cassette portion is also configured to be placed in fluid communication with the blood filter and with an extracorporeal circuit communicating with the blood filter, the fluid communication enabling hemodiafiltration to be performed. The example disposable unit also includes a heater bag configured to be placed in operable communication with the medical fluid heater and in fluid communication with the medical fluid cassette portion.
Owner:VANTIVE US HEALTHCARE LLC +1

Extracorporeal bioengineered dual-cell liver regeneration system (EBDLR) and bio purifier therefor

A multi-layered bio purifier includes a plurality of layers. Each layer may include a membrane having a first side and a second side opposite the first side, a first channel formed on the first side, and a second channel formed on the second side. Further, each layer may include a first type of cells formed on the first side in the first channel and a second type of cells formed on the second side in the second channel. The multi-layered bio purifier includes a first manifold assembly to split incoming blood into the first channel and the second channel of the plurality of layers and a second manifold assembly to combine processed blood from the first channel and the second channel of the plurality of layers. The processed blood may include detoxified or purified blood.
Owner:YKRITA LIFESCIENCES PTE LTD

A system for extracorporeal and intracorporeal wound closure and a suture cartridge thereof

A system for performing any of extracorporeal or intracorporeal wound closure, includes a suture cartridge 100 configured to be detachably coupled to a distal end of a handle of the system extracorporeal wound closure, or to a shaft assembly that is coupled to distal end of the handle for intracorporeal wound closure. On being coupled to any of the shaft assembly or the handle, a driving pulley 112A of the cartridge 100 gets operatively coupled to a driving mechanism in the handle to drive a belt 110 of the suture cartridge 100 to drive a suturing needle 106 for suturing tissues for the extracorporeal or intracorporeal wound closure. The cartridge 100 can be coupled with any of a robotic system, a hand held system and a minimal invasive surgical system.
Owner:DENOVO BIOINNOVATIONS PTE LTD

Cardiac surgery extracorporeal circulation pipeline fixing system

The invention belongs to the technical field of pipeline fixing devices, and particularly relates to a cardiac surgery extracorporeal circulation pipeline fixing system which comprises a fixing base and a pipeline clamping module located at the top of the fixing base, and the pipeline clamping module comprises a fixing plate. The device is tightly adsorbed to the surface of an operating table through a fixed suction cup, a second supporting seat is automatically leveled through a hydraulic buffer, the second supporting seat is always in a horizontal stable state, and a first clamping block and a second clamping block are controlled to be buckled through a pipeline clamping module by extruding arc-shaped clamping plates on the two sides; a first clamping block and a second clamping block are fixed through rotation of a limiting block, a pipeline is preliminarily fixed, pressure adjusting plates on the two sides are controlled by a pressure adjusting knob to move in the opposite direction, and the clamping force can be finely adjusted according to the factors such as the material and thickness of the pipeline; the problem that the blood flow stability is influenced by the body position change of a patient or the traction of a surgical instrument and other factors of the pipeline fixing device in the surgical process is solved.
Owner:XIEHE HOSPITAL ATTACHED TO TONGJI MEDICAL COLLEGE HUAZHONG SCI & TECH UNIV

Extracorporeal bioengineered dual-cell liver regeneration system (EBDLR) and bio purifier therefor

An EBDLR system includes a multi-layered bio purifier having a plurality of layers. Each layer includes a membrane, a first type of cells on a first side of the membrane in a first channel, and a second type of cells on a second side of the membrane in a second channel. The EBDLR includes a plasma separator to receive blood from a subject and separate a plasma component from the blood, a first reservoir to collect the plasma component, and a second pump to move the plasma component from the first reservoir to the multi-layered bio purifier. The multi-layered bio purifier distributes the plasma component into the first and second channels of each layer to purify the plasma component. The EBDLR includes a second reservoir to collect the purified plasma component and a third pump to infuse the purified plasma component from the second reservoir into the subject.
Owner:YKRITA LIFESCIENCES PTE LTD

Portable self-adaptive extracorporeal shock wave orthopedic treatment device

The portable self-adaptive extracorporeal shock wave orthopedic treatment device comprises a bandage, a treatment head and a fixing band, the bandage is composed of a bandage body and a base, and the section of the bandage body is in a U shape; the edge of the base is connected with the edge of the bandage body, and the base and the bandage body define a closed cavity. A plurality of mounting holes are formed in the substrate at intervals; the treatment head is mounted at the mounting hole in the base, and the action end of the treatment head extends towards one side far away from the cavity; the treatment heads at different positions can generate extracorporeal shock waves with different intensities and frequencies according to the bone mineral density loss condition to act on a human body part; the fixing bands are installed at the two ends of the bandage, and during use, the bandage surrounds the part, needing to be treated, of the body and is fixed through the fixing bands. The device self-adaptively recognizes the condition of a to-be-treated part of a patient, and accurately sends out shock waves to prevent and treat bone loss; the device is portable and small, can be used under microgravity, can be operated by a patient, and improves the treatment convenience.
Owner:TIANJIN UNIVERSITY OF TECHNOLOGY

Medical treatment device

The invention relates to a medical treatment machine with connection points for disposable tubing that can be connected to a patient's extracorporeal circuit. To improve hygiene, these connection points are optimally dried before the disposable tubing is connected.
Owner:FRESENIUS MEDICAL CARE DEUTSCHLAND GMBH

Absorbent structure for a sinus stent

The application provides a sinus intubation extracorporeal water absorption structure, and relates to the technical field of sinus intubation extracorporeal water absorption, which comprises a drainage tube, a sticking accessory, a negative pressure bag, a first one-way valve, a liquid storage bag and a second one-way valve. One end of the drainage tube is used for insertion into a sinus and for absorbing sinus exudate. The sticking accessory is connected with the drainage tube and is used for sticking to the skin of a patient, so as to detachably stick the drainage tube to the skin and block the sinus opening. The inlet end of the first one-way valve is connected with the end of the drainage tube away from the sinus, the outlet end of the first one-way valve is in communication with the inlet of the negative pressure bag, and the negative pressure bag is configured to automatically elastically recover and generate negative pressure on the drainage tube when it is released after being manually squeezed. The inlet end of the second one-way valve is in communication with the outlet of the negative pressure bag, and the outlet of the second one-way valve is detachably communicated with the liquid storage bag. The sinus intubation extracorporeal water absorption structure has the advantages of simple structure, low cost, self-management of the patient and no limitation on the activity of the patient.
Owner:CHENGDU MILITARY GENERAL HOSPITAL OF PLA

Anti-bruise drainage tube and drainage tube assembly

The utility model relates to an anti-bruise drainage tube and a drainage tube assembly, and belongs to the technical field of drainage tubes. Comprising a drainage tube body, and the drainage tube body comprises an in-vivo tube section and an in-vitro tube section which are independent; a flow guide channel is arranged in the pressure-proof base; a first connecting end and a second connecting end which are communicated with the flow guide channel are arranged on the pressure-resistant base; the pressure-resistant base is provided with a bottom face used for being attached to the skin. Wherein one end of the in-body pipe section is fixedly connected with the first connecting end in a sealing manner; one end of the in-vitro pipe section is hermetically and rotatably connected with the second connecting end, so that the in-vitro pipe section can circumferentially rotate relative to the pressure-resistant base; and the bottom surface is provided with a bonding part fixed with the skin. The in-vitro pipe section can adjust the leading-out angle along with the actions of turning over, sitting up and the like of the patient, so that the lateral turning torque generated on the pressure-resistant base due to rigid traction of the pipeline is greatly reduced, and the bottom surface is always stably attached to the skin.
Owner:SICHUAN ACADEMY OF MEDICAL SCI SICHUAN PROVINCIAL PEOPLES HOSPITAL

Emergency treatment in-vitro cooling device

The invention belongs to the technical field of emergency nursing, and particularly relates to an emergency in-vitro cooling device which comprises a frame, a mounting plate is arranged at the bottom of the frame, and a water tank is mounted in the center of the top surface of the mounting plate; through cooperative use of a cooling plate and a heat exchange pipe, heat on a patient can be conducted to a heat conducting plate through the cooling plate and conducted to the heat exchange pipe through the heat conducting plate, then a first water pump is started, and the first water pump conveys water in a water tank into the heat exchange pipe through a first water outlet and conveys the water back into the water tank through a first water inlet; water liquid can circularly flow in the heat exchange pipe, when the water flow flows in the heat exchange pipe, heat on the heat exchange pipe and the heat conducting plate can be rapidly taken away, and the cooling plate can continuously conduct heat of the whole body of a patient, so that the whole body of the patient is effectively cooled, and the in-vitro cooling effect on the patient during emergency nursing is improved.
Owner:THE AFFILIATED HOSPITAL OF XUZHOU MEDICAL UNIV

Line arrangement device for valve replacement surgery

The utility model relates to the technical field of medical instruments, and particularly discloses a line arrangement device for a valve replacement operation. The mounting cover is arranged outside the frame body; the wire arranging mechanisms are installed outside the two sides of the installation cover, clamping grooves are formed in the two sides of the installation cover, a fixing mechanism is installed at the bottom end of the installation cover, each wire arranging mechanism comprises a wire arranging base, a wire arranging groove and a tension spring, and the wire arranging bases are fixedly connected to the outer side wall of the installation cover; according to the valve wire arrangement device, through the arrangement of the wire arrangement base, the wire arrangement groove, the tension spring and the clamping groove, when a valve operation is conducted, a valve wire is firstly placed in the wire arrangement groove, then the valve wire is clamped and fixed by stretching the tension spring, wire arrangement operation can be conducted on the valve wire, and the arranged clamping groove can fix an extracorporeal circulation pipeline; and the operation is more convenient, so that the valve replacement operation can be smoothly performed.
Owner:LANZHOU UNIV SECOND HOSPITAL

Brain-machine interface extracorporeal machine

1. The name of the design product: brain-computer interface external machine. 2. The use of the design product: for electroencephalogram signal processing and information transmission. 3. The design points of the design product: in shape. 4. The picture or photo that best indicates the design points: perspective view 1.
Owner:SHENZHEN WE LINKING MEDICAL TECHNOLOGY CO LTD +1

Ultrasound barrier chamber for fluid systems

Disclosed herein is an ultrasound barrier chamber for a fluid system, e.g., which facilitates the de-air of a fluid line using an ultrasound signal. In some examples, the fluid line may include, for example, an extracorporeal blood circuit for use in a dialysis process. In one example, a device for monitoring an extracorporeal circuit having a blood pump disposed therein to deliver blood may include one or more ultrasound transducers positioned in a predetermined vicinity of a vent of an instillation chamber of the extracorporeal circuit, one or more ultrasound transducers positioned in a predetermined vicinity of the vent of the instillation chamber of the extracorporeal circuit, and one or more ultrasound transducers positioned in a predetermined vicinity of the vent of the instillation chamber of the extracorporeal circuit. And a controller coupled to the one or more ultrasound transducers, the controller configured to enable the one or more ultrasound transducers to transmit an ultrasound signal that displaces particles in the contents of the instillation chamber away from the vent. Other embodiments are described.
Owner:FRESENIUS MEDICAL CARE HOLDINGS INC

Oxygenator mounting bracket capable of being quickly fixed and ECMO (extracorporeal membrane pulmonary oxygenation) rack car

The invention relates to the technical field of medical instruments, in particular to an oxygenator mounting support capable of being quickly fixed and an ECMO (extracorporeal membrane pulmonary oxygenation) rack car, which comprise a base, a central controller, a variable temperature water tank, an oxygenator, a centrifugal pump, a blood storage device and a power box, two connecting plates are fixedly connected to the inner sides of the four supporting rods, a central controller is placed on the upper surface of one connecting plate, a variable-temperature water tank is placed on the upper surface of the other connecting plate, a power box is placed on the upper surface of the base, and three movable assemblies are arranged on the outer surfaces of the three supporting rods correspondingly. Through the arrangement of the movable assembly and through the first connecting rod and the second connecting rod which can stretch and contract, the left-right position can be adjusted according to the actual situation, and operation is convenient and fast; and the locking assembly is used for limiting, so that the adjusting angles of the first connecting rod and the second connecting rod can be quickly and stably locked, and the displacement phenomenon of the first connecting rod and the second connecting rod is avoided.
Owner:QUZHOU PEOPLES HOSPITAL (QUZHOU CENT HOSPITAL)

Intubation tube protector in-vitro fixing device

The utility model relates to the technical field of medical instruments, in particular to an in-vitro fixing device for a cannula protector. The in-vitro fixing device for the cannula protector comprises a limiting plate, a binding piece and a clamping and fixing assembly, the limiting plate is used for being attached to the outside of the lips of a patient, the binding piece is connected between the two ends of the limiting plate and used for being bound to the head of the patient, a notch for a cannula to penetrate through is formed in the limiting plate, and the clamping and fixing assembly is connected with the limiting plate. The clamping and fixing assembly is arranged on the outer side of the notch of the limiting plate and used for clamping the insertion pipe penetrating through the notch. The cannula fixing device has the advantages that the structural design is simple and reasonable, the cannula can be effectively fixed after cannula insertion, and displacement of the cannula in the length direction of the cannula is avoided.
Owner:武汉惟术医疗技术有限公司

Catheter pump clamping device and in-vitro simulation circulating system

The invention discloses a conduit pump clamping device and an in-vitro simulation circulating system, the conduit pump clamping device comprises an inlet flange and an outlet flange, and fluid flows from the inlet flange to the outlet flange. A penetrating pipe is arranged in the outlet flange, one end of the penetrating pipe communicates with the first cavity, and the other end of the penetrating pipe penetrates through the side wall of the outlet flange and extends out of the outlet flange. The far end of the catheter pump can penetrate into the catheter pump clamping device through the penetrating pipe until the fluid inlet in the catheter pump is located in the first cavity, and the fluid outlet in the catheter pump is located in the penetrating pipe. At the moment, the fluid entering the outlet flange can flow out in two ways: the fluid is pumped out through the conduit pump or flows out from a fluid outlet on the outlet flange. In this way, the pumping flow of the conduit pump in the auxiliary process can be obtained by measuring the fluid flow of the penetrating pipe; and the fluid can be converged after flowing out, and the total flow of the artery can be obtained by measuring the converged flow, so that a tester can evaluate the real performance of the catheter pump.
Owner:SHANGHAI PHIGINE MEDICAL CO LTD +1

Headstock with multi-position fixing structure special for cardiac surgery

The invention relates to the technical field of medical instruments, in particular to a special cardiac surgery head frame with a multi-body-position fixing structure, which comprises a mounting frame, a rotating rod is rotatably connected to the inner wall of the mounting frame, two round tubes are rotatably connected to the outer wall of the rotating rod, and a first fixing block and a second fixing block are fixedly connected to the outer walls of the round tubes respectively. Electromagnets are fixedly connected to the positions, corresponding to the first fixing block and the second fixing block, of the inner wall of the mounting frame, and through magnetic attraction control and arc-shaped limiting block design, switching of three modes of synchronous rotation of the head and the body, independent rotation of the head and independent rotation of the body is achieved; when the head is placed, a conical linkage structure is triggered by means of gravity, a supplementary air bag is extruded to supply air to a fixed air bag, placing, namely clamping and air bag attaching to the head are achieved, the risk of pressure sores is reduced, a fourth spring can drive the air bag to automatically return air and reset, manual operation is not needed, and operation is convenient. And the operation interference during the operation is reduced.
Owner:3201 HOSPITAL

Simulation cycle test system for extracorporeal membrane oxygenation ECMO

InactiveCN120369360AOther blood circulation devicesMedical devicesMembrane oxygenatorsData set
The invention discloses a simulation cycle test system for extracorporeal membrane oxygenation ECMO, and relates to the technical field of medical instrument extracorporeal test. The system comprises a training data acquisition module for acquiring blood flow characteristic parameters of users with different body characteristic parameters and generating a training sample data set. The prediction model training module establishes a neural network model and trains the blood flow feature extraction model. The physiological feature analysis module predicts blood flow feature parameters by simulating body feature parameters of a user and sets blood exchange flow velocity and pressure according to predicted values. The exchange parameter adjusting module is used for dynamically adjusting the set flow velocity and pressure and acquiring blood quality parameters under the operation condition. The blood quality adjusting module is used for correcting the gas flow of the membrane oxygenator according to the obtained blood quality parameters, the ECMO simulation cycle test is completed, refined gas flow management is achieved, and the oxygenation efficiency is improved.
Owner:THE THIRD AFFILIATED HOSPITAL OF SOUTHERN MEDICAL UNIV (ACAD OF ORTHOPEDICS GUANGDONG PROVINCE)

Adjustable-size extracorporeal life support cannula

A cannula (100) for an extracorporeal life support system may include a tubular element (110) and an actuation structure (140). The actuation structure (140) may be configured to be sensitive to an external stimulus such that an internal diameter of the tubular element (110) changes when the external stimulus changes. A system may include the cannula (100) and a control device (30) in electrical communication with the actuation structure (140). The control device may be configured by a user to set a desired value for an internal diameter of the tubular element (110). Figure for the abstract: Fig. 1
Owner:CARDIACASSIST INC

Advanced methods and system for controlled whole body hyperthermia

An advanced system and methods for treatment of cancer and other diseases including complications from late-stage viral infections by inducing hyperthermia in a patient relying on withdrawing blood from the patient and returning the withdrawn blood to the patient to establish a continuous extracorporeal flow circuit. Blood is heated by passing through the extracorporeal circuit at a controlled rate until a target body core temperature in is achieved. An innovative concept inherent in the instant invention is the incorporation of an ECMO machine to provide oxygenation. Usually, the blood will be subjected to a continuously re-circulating dialysis to balance electrolytes. Additionally, the blood will be subjected to a continuously recirculating regeneration through a carbon sorbent column where toxins and contaminants are removed. The blood temperature is maintained at the target blood temperature for a treatment period, and the blood is cooled after the treatment period has been completed.
Owner:VERTHERMIA INC

Emergency treatment in-vitro cooling device

The invention relates to the field of cooling devices, in particular to an emergency treatment in-vitro cooling device which comprises a bed plate, a limiting plate assembly, a trunk area cushion, a head area cushion, a cooling pipe, a cooling water tank, a water tank inlet and outlet pipe set, a head cooling assembly and a trunk cooling assembly. A limiting plate assembly used for limiting the fever patient from moving disorderly after lying down is installed on the rear side of the upper end of the bed plate. A fever patient is limited to move disorderly after lying down through the limiting assembly, the back, the head and the neck of the lying patient can be subjected to water cooling, heat of the body surface is effectively taken away, the body temperature is rapidly reduced, meanwhile, the chest area, the hand area and the leg area of the patient are all coated with alcohol through the alcohol smearing roller moving front and back, and therefore the patient feels comfortable. The cooling device is long in duration time, capable of reducing side effects or anaphylactic reactions possibly caused by drugs, high in automation degree and quite suitable for emergency treatment.
Owner:THE FIRST AFFILIATED HOSPITAL OF ARMY MEDICAL UNIV

Extracorporeal oxygenator with integrated air removal system

Extracorporeal blood flow circuit devices can be used during medical procedures such as on-pump open-heart surgery. For example, extracorporeal heat exchange and oxygenation devices can be used to facilitate surgical procedures such as coronary artery bypass grafting. In some embodiments, such an oxygenation device can include an integrated air removal structure. In particular embodiments, the air removal structure can comprise one or more porous hollow fibers.
Owner:TERUMO CARDIOVASCULAR SYSTEMS CORP

Interventional pump in-vitro simulation cycle test device

The invention discloses an intervention pump in-vitro simulation cycle testing device which comprises a supporting system, a blood pump system, a bionic cardiovascular simulation system, a sensing and measuring system and a control system. The support system is used for bearing and fixing each component and integrating an electric signal input interface and a serial communication interface; the blood pump system comprises a servo motor and a base, and the servo motor rotates to drive the base and the bionic left ventricle model to rotate; the bionic cardiovascular simulation system comprises a bionic left ventricle model, a valve device and a simulated cardiovascular loop, and the sensing and measuring system is used for monitoring hemodynamic parameters of the loop in real time; and the control system is used for receiving the hemodynamic parameters and controlling the servo motor to output motion meeting physiological characteristics. The device is simplified in structure, high in integration level, modular in design, capable of supporting quick disassembly and assembly, improved in maintenance efficiency, capable of reducing operation difficulty and personal errors and capable of reducing blood injury risks at the same time. The system is high in control stability and high in physiological simulation precision.
Owner:SHANGHAI JIAOTONG UNIV

Extracorporeal blood circulation

PCT designated stage expiredWO2025031839A1Positive displacement pump componentsIntravenous devicesPulsatile blood flowNormal blood volume
The invention relates to a method and a corresponding device, by means of which device an extracorporeal, pulsatile blood circulation with purely laminar flow is generated. Without additional shear load caused by the device itself. For this purpose, closed annular channels (12) completely filled with blood (2) are rotated in their main plane. A pulsatile blood flow always in the same direction comes about because the constant rotation of the annular channel (12) is quickly stopped. A laminar blood flow arises relative to the channel and comes to a standstill again. By interruption of the annular channel (12) by means of a blocking device (30), the blood (2) remains at rest relative to the channel even when rotation is started again. The blocking device (30) is not opened again until constant rotation has been reached, and the process is then repeated cyclically. The combination of annular channel (12) and blocking device (30) in one part allows the test setup to be considerably reduced in size. A plurality of samples having a small blood volume can then be tested in parallel by means thereof. When the blood circuit is divided into a movable hose loop (6) having stationary, open hose ends (61) (62) and into an external connection (63) thereto, the device operates as a blood pump.
Owner:KUNZE EBERHARD

Left heart suction device and method for cardiac surgery

The invention relates to a cardiac surgery left heart suction device and method, and relates to the related field of medical instruments.The cardiac surgery left heart suction device comprises a workbench, a plurality of supporting legs fixed to the bottom of the workbench and two first movable grooves, the two first movable grooves are formed in the two sides of the workbench, and supporting bases are slidably installed in the two first movable grooves; rolling assemblies and transmission rods are installed on the two supporting seats, the transmission rods are installed at the bottom of the workbench in a sliding mode, the two rolling assemblies are connected through the transmission rods, and when a suction tube body is installed, only the two ends of the suction tube body need to be clamped into limiting pieces, and the suction tube body is installed. The middle of the suction tube body is placed in the second tube groove of the straightening plate, then the suction tube body can be automatically mounted / dismounted, the mounting precision is relatively high, the suction tube body can be mounted in the rolling assembly in the shortest time in the most standard mode, and extracorporeal circulation is provided for a patient in the shortest time.
Owner:FUWAI HOSPITAL CHINESE ACAD OF MEDICAL SCI & PEKING UNION MEDICAL COLLEGE

Use of TREM-1 for predicting and preventing postoperative complications after cardiac surgery with cardiopulmonary by-pass

Cardiopulmonary by-pass (CBP) during cardiac surgery leads to deleterious systemic inflammatory response. In a prospective cohort of 46 patients older than 18 years and eligible for non-urgent cardiac surgery with CPB, measurement of sTREM-1 in the plasma was performed immediately after the onset of anesthesia (H0) and 2 and 24 hours after CBP. After CBP, sTREM-1 significantly increased at H2 and at H24 (p<0.001). Based on both baseline sTREM-1 levels and variations. 3 patterns of patients were identified. Profile 1 group with high baseline sTREM-1 levels as well as high increase, developed more severe organ failure after CBP with higher norepinephrine dose at H24, higher SOFA score and more frequently AKI at both H24 and H48. Finally, acute atrial fibrillation at H24 was more frequent in profile 1 when compared to profile 2 / 3, Profile 1 group had longer ICU and hospital length of stay (LOS). In conclusion, early sTREM-1 variations after cardiac surgery identified a group of patients at high risk for post-operative AKI and prolonged length of stay. Thus sTREM-1 represents a relevant biomarker and biotarget in cardiac surgery with CBP.
Owner:INST NAT DE LA SANTE & DE LA RECHERCHE MEDICALE (INSERM) +5