42 results about "Aortic valve replacement" patented technology

Methods and apparatus are provided for valve repair or replacement. In one embodiment, the method comprises providing an apparatus having a valve prosthesis, a valve leaflet support and a valve excisor, the apparatus having a first configuration and a second configuration; accessing the aortic root without placing the patient on a heart-lung machine; advancing the apparatus in the first configuration where the valve leaflet support is advanced through a valve, wherein the support is positioned below a valve annulus; expanding the apparatus into a second configuration so that the support will engage the valve; and moving the valve leaflet support and valve excisor together to remove leaflets of the valve. Penetrating members may be advanced into the tissue wherein the penetrating members may act as fasteners to hold the prosthesis in place.

A surgical stapler for securing a prosthetic heart valve within a patient generally includes a first cylindrical portion for carrying at least one staple assembly on a distal end thereof; a second cylindrical portion positioned concentrically about the first cylindrical portion and having a camming arm on a distal end thereof, the camming arm configured to cam the at least one staple assembly radially outward and drive the at least one staple assembly distally such that a first leg of the at least one staple assembly penetrates a cuff of the prosthetic heart valve and a second leg of the at least one staple assembly pierces a portion of heart tissue surrounding the prosthetic heart valve, as the second cylindrical portion is moved distally relative to the first cylindrical portion; and a third cylindrical portion positioned concentrically about the second cylindrical portion and having an anvil flange on a distal end thereof, the anvil flange configured to crimp the second leg of the at least one staple assembly toward the first leg of the at least one staple assembly to secure the prosthetic heart valve to the surrounding heart tissue as the third cylindrical portion is moved relative to the second cylindrical portion. A method of installing a heart valve within a patient which includes the steps of accessing a site within a heart from which a natural heart valve has been removed; lowering a prosthetic heart valve into position within the site in the heart; positioning a surgical stapler having at least one staple assembly removably held on a distal end thereof adjacent the prosthetic heart valve within the site in the heart; driving a first leg of the at least one staple assembly through a peripheral cuff of the prosthetic heart valve; and crimping a second leg of the at least one staple assembly in a direction toward the first leg such that the second leg pierces a portion of heart tissue surrounding the prosthetic heart valve, thereby securing the prosthetic heart valve to the surrounding heart tissue.

A replacement cardiac valve for placement adjacent the native annulus comprises a valve body having a multi-leaflet valve, a supporting stent surrounding and operatively coupled to the valve body, a superior O-ring and an inferior O-ring spaced from one another to span the native annulus, the O-rings surrounding the valve body and operatively coupled the valve body or the supporting stent, the valve body, the supporting stent, and the O-rings adapted for transcatheter placement using a deployment catheter.

The present invention describes a cardiac prosthetic system (400) comprising: an anchoring conduit (200) having a harbour (415), the harbour including a first releasably engaging component (515); a temporary valve (305) and a heart valve prosthesis (420) having a second releasably engaging component (445) enabled to be securely coupled and uncoupled from the first releasably engaging component (515) of the harbour (415).

A minimally invasive method of implanting a prosthetic aortic valve includes forming a surgical site within a patient's chest that includes a first access port, a second access port, a viewing port and a delivery port. A camera is inserted into the viewing port. The native aortic valve leaflets may each be grasped and removed via tools inserted through the first and second access ports. The prosthetic aortic valve may be delivered through the delivery port to the valve annulus using a delivery device. The prosthetic aortic valve is implanted at the valve annulus and the delivery device is withdrawn. A surgeon may perform the remotely operated steps while viewing images provided by the camera.

A device for replacement of a bioprosthetic valve having an annulus (104) and one or more leaflets (105), the device having an outer housing (106) and an inner shaft (108) with a distal end (110). The outer housing (106) is slideable relative to the inner shaft (108) such that a portion of the inner shaft (108) may be revealed. A cap (112) is associated with the distal end (110) of the inner shaft (108), the cap (112) movable between a first position adjacent the inner shaft (108) and a second position displaced from the inner shaft (108). The cap (112) is adapted to trap a skirted valve frame (102) between said cap (112) and the inner shaft (108) when in the first position. The skirted valve frame (102) may be released by the cap (112) upon sliding of the outer housing (106) relative to the inner shaft (108) to reveal the inner shaft (108) and upon movement of the cap (112) to the second position. Also disclosed are associated methods.

The invention discloses an artificial aortic valve ring system, which is used for taking effects of supporting and fixing in trans-catheter aortic valve replacement on patients of aortic valve regurgitation without calcification. The system comprises a valve ring scaffold at distal end and anchoring legs at proximal end, wherein the valve ring scaffold is fixedly connected to the anchoring legs; the valve ring scaffold is of a tubular structure and has a gridding structure; the anchoring legs are arranged along the periphery of the valve ring scaffold and are embedded in a cavity structure on ascending aortic root so as to fix the system; and the system is capable of transforming between a first form of radial expansion and a second form of radial shrinkage. With the implantation of the system, the trans-catheter aortic valve replacement on patients of aortic valve regurgitation without calcification becomes possible.

The invention discloses an aortic valve fluid-solid coupling numerical simulation method based on CT medical image data, and belongs to the field of aortic valve and fluid-solid coupling numerical simulation. The method comprises the following steps: acquiring heart CT medical image data; reconstructing a valved aorta root model based on the CT medical image data; carrying out fluid-solid couplingnumerical simulation; and verifying the aortic valve model. According to the invention, the aortic valve model is reconstructed through CT medical image data, aortic root fluid-solid coupling numerical simulation is carried out based on Comsol software, and the complex deformation problem of the aortic valve in the complete cardiac cycle is solved. The method truly reflects the hemodynamics of the root of the aorta, and the result has more guiding significance for reality. The aortic valve fluid-solid coupling numerical simulation developed by the invention can provide reference for artificial valve design and aortic valve replacement.

The invention provides a seamless aortic valve replacement device implanted under surgical orthophoria. The seamless aortic valve replacement device is characterized by comprising a metal support, a terylene ring, a joint tab and an artificial valve, wherein the metal support comprises a support inflow end, an oar-shaped support part and a support outflow end, wherein the oar-shaped support part is connected with the support inflow end and the support outflow end respectively; the terylene ring is fixed at the support inflow end; the joint tab is fixed at the oar-shaped support part; and a near end of the artificial valve is fixed on the inner side of the terylene ring, and a far end of the artificial valve is fixed on the inner side of the joint tab. According to the seamless aortic valve replacement device, the whole height of the device can be effectively reduced; and at the same time, large-area circular terylene is seamed at the support inflow end, fixation of the whole device in a left ventricle outflow tract is enhanced, and integrated expansion is facilitated, so that the inflow end and the outflow end of the metal support can be well anchored an aorta wall, and the occurrence rate of complication of valve displacement, perivalvular leakage, atrioventricular block and the like is decreased.

The invention relates to a kind of tPA gene suture as well as preparing method, the characteristic of the invention is that the eukaryotic expression vector pSecTag2B-t-PA of modified gene tPA is attached to the suture. The preparing procedure includes the following steps: labeling the pSecTag2B-t-PA recombinant plasmid with basic ion bangosome; soaking the suture into bangosome/plasmid DNA compound solution repeatedly to get the tPA gene suture. The invention can be used in the saturation of cardiac muscle in cardiac valve replacement; it can remove or prevent the sludged blood so that it can prevent the form of thrombus around the valvula which can impact the valvula function after cardiac valve replacement.

The invention relates to a method and a system for optimizing cardiac valve replacement. The method comprises the following steps: (1) calculating load forces of different patients after transcatheteraortic valve replacement; (2) simulating the behavior of aortic root and valve tissue, and extracting biomechanical characteristics by finite element method; (3) establishing an aortic valve insufficiency risk prediction model; (4) using the risk prediction model to predict the risk of heart valve and optimize the prosthetic valve, repeating the steps (1)-(3) until the risk prediction results aresafe. As compare with that prior art, the method and system of the present invention can guide doctors to use different optimize valves for different patients to minimize clinical risks.

The invention discloses a bicuspid percutaneous aortic valve incision device, which comprises a conveying device and a cutting device; the conveying device comprises an outer sheathing canal, a middle sheathing canal and a hollow inner sheathing canal; the inner sheathing canal is movably sheathed in the middle sheathing canal; the middle sheathing canal is movably sheathed in the outer sheathing canal; the cutting device comprises two fixed mounts and blades respectively arranged on the fixed mounts; the length of each fixed mount is greater than the external diameter of the outer sheathing canal; the fixed mounts are rotatably arranged on the excircle surface of the far end of the inner sheathing canal; when the inner sheathing canal shrinks into the middle sheathing canal, the fixed mounts and the inner sheathing canal are axially contained in the middle sheathing canal in parallel; when the inner sheathing canal extends out of the outer sheathing canal, the two fixed mounts are fixedly arranged on the excircle surface of the inner sheathing canal in a straight line. The invention provides the bicuspid percutaneous aortic valve incision device which is simple in structure, does not need to implant outside matter and has a good treatment effect, so that the defects that surgery sequelae are numerous and the recovery degree is low due to the fact that the fixed mounts need to be implanted by adopting the existing novel aortic valve replacement are solved.

The invention relates to a tubular supporting prosthesis, comprising two terminal regions relative to the longitudinal supporting prosthesis axis and a center region disposed between the two terminal regions, wherein every terminal region is provided with a mesh structure made of at least two structural rings, which are connected to each other via connecting members and are disposed point-symmetrically about the longitudinal supporting prosthesis axis. The center region is formed by elongated connecting members, which are connected to the structural rings respectively disposed adjacent to the center of the longitudinal supporting prosthesis axis. An aortic valve, which is produced by means of tissue engineering, is fastened and/or integrated in the center region.

The invention discloses a coronary artery protecting device which comprises an isolating part and a fixing part. The isolating part is used for isolating a potential obstacle from a coronary artery opening, and the fixing part is used for fixing the position of the isolating part. The device is provided with a grid structure, the grid structure is implanted into the joint portion of the ascending aorta and coronary artery through the peripheral arterial path, the grid structure is implanted before transcatheter aortic valve replacement, smoothness of blood flow in the coronary artery during the transcatheter aortic valve replacement operation and after the operation can be guaranteed, coronary occlusion complications is avoided, and therefore transcatheter aortic valve replacement can be achieved for an aortic valve disease patient whose ascending aorta root anatomical structure does not meet the current standard.

A docking device for aortic valve replacements is a self-expanding nitinol structure including a lattice forming a tubular (e.g., cylindrical) upper framework or cage, and three struts forming a lower structure. The struts are formed by elongated loops that are attached to the lattice or that are an integral part of the upper framework. The struts extend down beneath the lattice, eventually forming “feet” to anchor at the base of the aortic cusps. The docking device can be positioned near a sinotubular junction of a patient. An aortic valve replacement is locked inside the docking device.

The invention mainly aims to provide a surgery aid which is applied to aortic valve replacement and mitral valve replacement and convenient for suturing artificial valves with the heart valve ring in an equal stitch length and uniform distribution manner, and relates to a drape used in cardiac surgery. The drape is characterized by comprising a heart drape body (24), and a round opening (23) is formed in the center of the heart drape body (24). The drape is characterized by further comprising a multifunctional ring (1) fixed outside the round opening (23), at least two mark points on the multifunctional ring can be used for quadrant partition, and the multifunctional ring has a surgery wire clamping function. By application of the mark type heart drape, occurrence of complications of perivalvular leakage and the like can be lowered greatly, the surgery time is shortened, the use time of all monitoring devices is shortened as well, and the medical cost of patients is lowered correspondingly.

The invention discloses an intervention bioprosthetic valve with a valve leaflet capable of being replaced repeatedly through minimally invasive surgery. The intervention bioprosthetic valve comprises a valve frame and the valve leaflet, wherein the valve frame and the valve leaflet are independent from each other, the valve frame and the valve leaflet can be installed on a valve ring in a minimally invasive intervention mode, and the valve leaflet can be demounted and mounted in the minimally invasive intervention mode. When the intervention bioprosthetic valve is implanted in a patient in a minimally invasive mode and the intervention bioprosthetic valve needs replacement due to the fact that functional degradation happens to the valve leaflet, a conveyer device provided with a new valve leaflet can be guided by a visualization device to remove the broken valve leaflet through the new valve leaflet on the conveyer device through minimally invasive surgery, meanwhile, the new valve leaflet is unfolded and installed on the valve frame to complete valve leaflet replacement, then, the broken valve leaflet is contained in the conveyer device and taken out of the body of the patient after being compressed, and therefore the replacement of the heart valve is completed. The design of the valve leaflet capable of being replaced repeatedly through minimally invasive surgery solves the problem of time limit of minimally invasive valve replacement.