16 results about "Valvular prosthesis" patented technology

A funnel crimper includes a body having a tapered portion, an extended outflow portion, and a tissue compressor. The tissue compressor is configured to apply a radially inward force to tissue of a prosthetic valve of a transcatheter heart valve prosthesis disposed on an inner surface of a frame of the transcatheter heart valve prosthesis as the transcatheter heart valve prosthesis is advanced through a lumen of the funnel crimper. The tissue compressor may be a ring of relatively soft material extending into the lumen of the funnel crimper or pressurized fluid applied radially inward to the lumen of the funnel crimper.

Systems and methods for synthesis of covers for valvular prosthetics are described. Generally, covers can be synthesized via depositing, submersion, and / or printing. Covers can be synthesized directly onto a valvular frame or synthesized on a temporary substrate and transferred onto the valvular frame. Covers can be synthesized having one or more layers. The covers and the various layers can be synthesized or treated to obtain beneficial properties.

A method of preventing paravalvular leakage includes concurrent delivery of a heart valve prosthesis and an annular sealing component. During delivery, the sealing component is moved from a first position to a second position of the heart valve prosthesis which is longitudinally spaced apart from the first position of the heart valve prosthesis. The sealing component is secured around the heart valve prosthesis at the second position by a contoured outer surface of the heart valve prosthesis. The sealing component may be a flexible ring or may be a cylindrical flexible sleeve having a plurality of ribs longitudinally extending over the cylindrical sleeve. The ribs operate to deploy the sealing component such that at least a portion of the cylindrical sleeve buckles outwardly away from the outer surface of the heart valve prosthesis.

Heart valve prosthesis implantation apparatus (10), comprising: - a prosthesis catheter (11) with a heart valve prosthesis (12) to be implanted, - an ICE catheter (9) - for insertion into a surrounding area of ​​a heart valve (HC) to be treated, - for detecting a relative position (RPHC) and / or a relative orientation direction (ROHC) of the heart valve (HC) to the ICE catheter (9) by means of an ultrasound image (USHC) of the heart valve (HC) through the ICE catheter (9), and - preferably for performing ultrasound images (USPC) of the prosthesis catheter (11), wherein the ICE catheter (9) is configured to determine an absolute reference position (ARPHC) and / or an absolute reference orientation direction (AROHC) of the heart valve, 2D ultrasound images in multiple planes, and / or 3D ultrasound images of the heart valve (HK) to create- a navigation system (51) for determining an absolute position (APICE) and an absolute orientation direction (AOICE) of the ICE catheter (9), - a control device (52) for controlling the insertion of the heart valve prosthesis (12) into the annulus of the heart valve (HC) based on the ultrasound images (USHK, USPK, USHKP) of the ICE catheter (9) and position and orientation direction information (APICE, AOICE, APPK, AOPK, APHKP, AOHKP) from the navigation system (51), - a display (53) for simultaneously displaying information (APHKP, AOHKP) regarding the position and / or orientation of the heart valve prosthesis (12) and the 2D ultrasound images and / or 3D ultrasound images for monitoring the insertion of the heart valve prosthesis (12) into the annulus of the heart valve, wherein the control device (52) is set up toto verify the correct insertion of the heart valve prosthesis (12) based on a comparison of the current position (APHKP) and / or the current orientation direction (ORHKP) of the heart valve prosthesis (12) with the determined absolute reference position (ARPHK) and the reference orientation direction (AROHK) of the heart valve (HC).

The present application provides a heart valve prosthesis, which has a first end and a second end opposite in a first direction; the heart valve prosthesis comprises a first support body, a second support body and an artificial valve leaflet; the first support body has a first edge and a second edge opposite in a second direction, which is perpendicular to the first direction; the second support body comprises a first segment, which is located on one side of the first support body and has a non-linear configuration; the first segment intersects the first edge at a first intersection point and intersects the second edge at a second intersection point; the second support body is connected with the first support body and allows the first segment to rotate relative to the first support body around a line connecting the first intersection point and the second intersection point; the artificial valve leaflet is connected with the edge of the second support body located on the side close to the first end and the first segment; the heart valve prosthesis has a contracted state and an expanded state; when the heart valve prosthesis switches from the contracted state to the expanded state, the first segment rotates and drives the middle part of the first segment to move in the direction close to the first end, and the distance between the middle part of the first segment and the first support body increases; when the heart valve prosthesis is in the expanded state, the area of the cross section of the artificial valve prosthesis perpendicular to the first direction first increases and then decreases along the first direction. The heart valve prosthesis can replace the native atrioventricular valve and / or the native arterial valve and has a larger effective valve orifice area.

A replacement heart valve prosthesis can be delivered to or within an existing prosthesis through a valve-in-valve delivery procedure. The existing prosthesis can be a prosthetic heart valve or other device that is implanted at a target site, such as an aortic or mitral valve of the heart. The methods provided herein can allow a surgeon to position a replacement prosthesis within or adjacent to an existing prosthesis and permit the replacement prosthesis to expand into engagement against the existing prosthesis. Thereafter, the surgeon can adjust components of the replacement prosthesis, including the position of separate anchor and frame components in order to ensure accurate and secure placement of the replacement prosthesis at the target site.

The present invention provides a valve stent and a usage method thereof for bicuspid aortic valve stenosis, comprising an ascending aorta contact area, a connecting body, a valve support area and a valve prosthesis suture part; the ascending aorta contact area is in an annular shape, a honeycomb-like structure formed by arranging and connecting a plurality of regular hexagons; the valve support area is in an elliptical annular shape, a grid structure formed by arranging and connecting a plurality of rhombuses. The present invention enhances the radial stiffness of the stent, thereby improving its radial support capacity; the valve support area is designed as an elliptical ring structure, and when implanting the artificial heart valve stent, the long-axis implantation angle of the valve stent is kept perpendicular to the long axis of the valve annulus, and by using the mutual coupling effect between the two, the cross-sectional shape of the expanded valve stent is finally circular, which improves the problem of poor expansion during the implantation of the valve stent and the elliptization after the valve stent is implanted, thereby reducing the occurrence of paravalvular leakage, with uniform stress and extended service life.

A heart valve prosthesis including an expandable stent frame having an interior area extending along an axis of the expandable stent frame between an atrial portion of the expandable stent frame and a ventricular portion of the expandable stent frame. A prosthetic valve structure is mounted within the interior area of the expandable stent frame. An expandable anchoring frame at least partially circumscribes the expandable stent frame. The expandable anchoring frame includes an atrial portion of the expandable anchoring frame and a ventricular portion of the expandable anchoring frame. The atrial portion of the expandable anchoring frame includes a circumferential segment that extends radially outward from an axis of the expandable stent frame. The circumferential segment is configured to deflect upon contact with native anatomy of a patient. The circumferential segment only partially circumscribes the axis of the expandable stent frame.

Prosthetic heart valve delivery systems are disclosed that have a stop that inhibits the system from passing beyond the point of no return where further deployment of a collapsed prosthetic heart valve may render it unable to be recaptured. An elongate catheter may include an outer cover configured to cover and uncover a collapsed prosthetic heart valve. The collapsed prosthetic heart valve is biased to expand radially outward as the outer cover uncovers the collapsed prosthetic heart valve. The system may also include a screw shaft and an actuator rotatable about the screw shaft to cause axial translation of a carriage, and thus the connected outer cover. The stop inhibits further rotation of the actuator, and thus further axial translation of the outer cover, and thus further deployment of the collapsed prosthetic heart valve.

A heart valve prosthesis and methods of its implantation are described herein. The prosthesis can be implanted in a heart of a patient by positioning an upper support of an anchoring element into a left atrium of the patient. The upper support can expand adjacent to a native valve structure of the patient. Further, the upper support can be moved against the native valve structure in a direction toward a left ventricle of the patient. A lower support of the anchoring element can be positioned into the left ventricle, spaced apart from the upper support, the lower support being separate from the upper support and coupled to the upper support by a flexible connector. Finally, the lower support can expand within the left ventricle, and engagement members of the lower support can engage with tissue of the native valve structure.

Methods and system for delivering heart valves are disclosed in which a stop inhibits the system from passing beyond the point of no return where further deployment of a collapsed prosthetic heart valve may render it unable to be recaptured. An elongate catheter may include an outer cover configured to cover and uncover a collapsed prosthetic heart valve. The collapsed prosthetic heart valve is biased to expand radially outward as the outer cover uncovers the collapsed prosthetic heart valve. The system may also include a screw shaft and an actuator rotatable about the screw shaft to cause axial translation of a carriage, and thus the connected outer cover. The stop inhibits further rotation of the actuator, and thus further axial translation of the outer cover, and thus further deployment of the collapsed prosthetic heart valve.

The present invention relates to a passageway and occluder device for managing and providing intentional regurgitation levels within transcatheter heart valve replacements, and specifically ortho-delivered transcatheter prosthetic heart valves having a first inner flow control component / valve, a second inner regurgitation control component, and an outer annular support frame having a compressible wire unit that facilitates collapsing along the z-axis and compressing the valve vertically along the y-axis or orthogonally to the central axis of the flow control component, thereby allowing very large diameter valves to be delivered and deployed from the inferior vena cava or superior vena cava to the tricuspid valve, or transatrially to the mitral valve, with a height of about 5-60 mm and a diameter of about 25-80 mm, without the need for an ultra-large diameter catheter and without the need to be delivered and deployed from the catheter at an acute angle of approach.

The present invention relates to a single stent spring element (10) for facilitating the implantation of a stent-supported transcatheter heart valve prosthesis (100) and to a stent-supported transcatheter heart valve prosthesis (100) comprising the single stent spring element (10). The single stent spring element (10) consists of a wire-like stent element (12) shaped to have a fixation section (13) and a deflection section (14), wherein the deflection section (14) has at least one side segment (18) and at least one curved segment (19), and wherein the deflection section (14) in its expanded state is deflectable by a deflection angle of greater than or equal to 5° to less than or equal to 45°.

Provided herein are devices and methods of valvular prostheses having a planar configuration during the delivery phase and a final closed folded configuration during deployment at the tissue targeted site. The stent can comprise an inner valve support for interfacing with valve prosthetic leaflets and an external cage. The cage can decouple the movement of the native heart valve from the inner valve support and the valve prosthetic leaflets.