20 results about "Venous valve" patented technology

A catheter for forming a fistula between two vessels. The catheter comprises a catheter body having a longitudinal axis, an electrode extending radially from the catheter body for contacting a vessel wall and forming the fistula, and a cutting unit disposed proximally or distally of the electrode for cutting a venous valve.

A DVT prevention and / or mitigation device includes a wearable band having an inflatable bladder with an inflatable portion. When the wearable band is disposed about a user's leg, a majority of the inflatable portion of the inflatable bladder is positionable between the user's knee and a midpoint of the user's gastrocnemius muscle. The inflatable bladder is also inflatable to apply pressure to a portion of the user's gastrocnemius muscle, and a source of compressed air is coupled to the wearable band to deliver continuous compression cycles to the inflatable bladder at a frequency of at least 3 cycles per minute, each compression cycle having a compression period and a peak inflation pressure to induce cyclic flow in the user's venous valve sinuses from each successive inflation.

The invention relates to a turbine disc cavity imitated venous valve type sealing structure and a design method thereof, an axial sealing gap simulates human body vein vascular tissue, and a sealing structure assembly is located in the axial sealing gap where a disc cavity is connected with a main flow channel and comprises two rows of imitated venous valve teeth on the static disc side and two rows of imitated venous valve teeth on the rotary disc side. Furthermore, the two groups of sealing structures are matched with each other, so that the gap is gradually shrunk outwards in the radial direction, a large amount of invading gas at the joint of the disc cavity and the main flow channel is blocked, and the gas is rectified by a vortex structure and enters the main flow channel again. By means of the modeling design of the sealing assembly, fluid, namely high-temperature fuel gas, is prevented from flowing into the disc cavity in the radial direction while the fluid is guided to flow outwards in the radial direction, mixing of high-temperature invasion fuel gas and sealing cold air is enhanced, the sealing cooling efficiency of the connecting area of the disc cavity and the main flow channel is improved, and the high-temperature heat load borne by the position is reduced; and the method is of great significance to safe operation of the whole gas turbine.

A system for forming a fistula between two vessels, the system comprising a first catheter. The first catheter comprises a catheter shaft with a housing. The first catheter further comprises an electrode disposed at least partially within the housing, the electrode comprising a distal portion, a proximal portion and an intermediate portion therebetween for contacting a vessel wall and forming the fistula. The first catheter further comprises a plurality of teeth for cutting a venous valve, wherein the plurality of teeth extend radially from the catheter shaft and are angled in a proximal direction.

This application generally relates to an transcatheter anti-reflux venous valve endoprosthesis system, including a replacement valve, a valve support frame, crimping system, and delivery system to treat patients with chronic venous insufficiency, and method for using such a system.

This application generally relates to an transcatheter anti-reflux venous valve endoprosthesis system, including a replacement valve, a valve support frame, crimping system, and delivery system to treat patients with chronic venous insufficiency, and method for using such a system.

The invention relates to a venous valve destruction structure for deep vein transcatheter arterization, and belongs to the technical field of medical devices, the venous valve destruction structure comprises a transcatheter, a venous valve knife and a limiting device, the venous valve knife is inserted in the transcatheter, the venous valve knife is provided with a moving rod, one end of the moving rod is provided with a venous valve blade with an expandable or contractible volume, and the other end of the moving rod is provided with the limiting device. The vein valve blade is retracted into the transcatheter, or the vein valve blade extends out of the transcatheter, and a handle is arranged at the other end of the moving rod; the limiting device is used for limiting the moving position of the venous valve knife and can be rotatably arranged outside the transcatheter, the venous valve knife penetrates through the interior of the limiting device, and the limiting device is connected with the moving rod through threads; the device has the advantages that the limiting device is rotated, the handle is controlled, the vein valve blade moves in one direction, the vein valve blade extends out of the transcatheter, and the vein valve is damaged through linear movement and rotation of the vein valve blade.

The present application discloses tissue grasping devices and related methods, particularly a clip for securing leaflets of a heart valve or venous valve, including a hub having a pair of anti-entanglement spring biased outer arms coupled to a lower end of the hub and a pair of anti-entanglement spring biased inner arms adjacent the outer arms and coupled to an upper end of the hub. A delivery catheter with a reinforcing member configured to position the valve clip proximate a target valve while the outer arms and inner arms are biased in an open position relative to one another. The delivery catheter or clip includes a suture that facilitates bailout. After the valve leaflets are positioned between the open outer arms and inner arms, the biasing force can be released to allow the clip to self-close the clip on the valve leaflets, thereby cinching and coapting the leaflets atraumatically and effectively.

A catheter for forming a fistula between two vessels. The catheter comprises a housing, an electrode disposed at least partially within the housing. The electrode comprises a distal portion, a proximal portion and an intermediate portion therebetween for contacting a vessel wall and forming the fistula. The catheter further comprises a valve destruction wire disposed at least partially within the housing for contacting and destroying a venous valve.

The present invention provides a valve material having synergistic anti-coagulation and anti-calcification functions and a preparation method therefor. The preparation method comprises the following steps: performing glutaraldehyde cross-linking treatment on an animal-derived biological valve material; immersing the treated valve material in a blocking solution containing an amine compound for 0.5-6 h, thereby blocking the remaining aldehyde groups after glutaraldehyde cross-linking; then placing the valve material into a reaction solution containing an anticoagulant and a cross-linking agent, and performing cross-linking treatment for 6-24 h at 4° C.-37° C.; and finally washing and obtaining the valve material, and storing the valve material in a mixed solvent of glutaraldehyde or isopropyl alcohol / glycerol. The method can effectively solve the problem of calcification and thrombosis caused by residual aldehyde groups in a valve material prepared by the existing method. The valve material prepared by the present method can be used as a valve material required for aortic valve, pulmonary valve, venous valve, mitral valve and tricuspid valve replacement.

The invention relates to a lower limb deep vein thrombus cleaning device, and belongs to the technical field of medical instruments. The thrombus removal device comprises a thrombus removal mesh basket assembly, the front end is inserted into a catheter in the blood flowing direction and penetrates through a vein valve and thrombus, and the thrombus removal mesh basket assembly is used for cleaning and containing the thrombus at the front end of the vein valve; the rotary telescopic assembly is arranged at the rear end of the thrombus extraction mesh basket assembly and used for controlling the thrombus extraction mesh basket assembly to stretch out, draw back and rotate in the target blood vessel so as to cut or scrape thrombus; the front end of the collecting assembly is inserted into the catheter in the blood flowing direction, abuts against the rear end of the vein valve and is used for cleaning and collecting thrombus at the front end and the rear end of the vein valve. The problem of cleaning blind areas caused by irregular outlines of the vein valve areas is effectively solved, and the thrombus cleaning device has the advantages that thrombus at the front end and the rear end of the vein valve can be cleaned at the same time, cleaning blind areas are effectively reduced, thoroughness of thrombus cleaning is improved, and thrombus residual risks are reduced.

Single and dual frame prosthetic venous valve assemblies, and catheter delivery systems and methods, are disclosed. A representative dual frame venous valve assembly includes an outer valve frame having a lumen and a frame and venous valve assembly arranged within the lumen. The frame and venous valve assembly, which also may be a stand- alone prosthetic venous valve assembly, includes an inner valve frame having a frame matrix forming lateral valve supports and valve commissure supports; a polymeric frame coating encapsulating the frame matrix; and a one or more polymeric leaflets integrally formed with or coupled to the polymeric frame coating, with each leaflet moveable between an open or partially open state and a closed or partially closed state. A delivery catheter includes keys or slots for insertion of locking tabs of the outer valve frame, and a deployment control handle for controlling deployment of the venous valve assembly.

The application provides a thrombus crushing device and a thrombus removing system. The thrombus crushing device comprises a thrombus crushing unit and a separation unit. The separation unit is connected with the proximal end of the thrombus removing head, and part of the separation unit is located between the transmission pipe and the thrombus crushing knife to shield part of the opening. The separation unit plays a role of blocking the blood vessel wall. That is, the separation unit can block the blood vessel wall and the venous valve from entering the thrombus removing head during the thrombus removing process, thereby reducing the damage. Moreover, the separation unit can separate the mural thrombus from the blood vessel wall while blocking the blood vessel wall during the thrombus removing process, thereby increasing the removing efficiency of the mural thrombus and improving the thrombus removing effect. In addition, the thrombus crushing knife, the separation unit and the thrombus removing head form a multi-layer cutting structure during the thrombus removing process, so that repeated cutting of the thrombus is realized, the thrombus crushing efficiency is improved, and the operation time is reduced. Therefore, the thrombus crushing device and the thrombus removing system provided by the application not only can protect the blood vessel wall, but also can improve the thrombus crushing efficiency and the thrombus removing effect.

Provided in the present disclosure are a prosthetic venous valve, a stent, and a prosthetic venous valve leaflet and a design method therefor, relating to the technical field of medical instruments. The stent involved in the present disclosure comprises a proximal segment support frame, a valve leaflet fixing assembly, a pocket-shaped support rod, and a distal segment support frame. The valve leaflet fixing assembly is connected between the proximal segment support frame and the distal segment support frame, and is configured for fixing the valve leaflet. A first end of the pocket-shaped support rod is connected to the proximal segment support frame, and a second end of the pocket-shaped support rod is connected to the distal segment support frame. When the stent is expanded, the pocket-shaped support rod can protrude along a radial direction of the stent in a direction away from the central axis of the stent, so as to form a pocket-shaped space on a proximal side of the valve leaflet fixing assembly.

A venous valve prosthesis for transporting a flow of body fluid in a vessel in a predetermined direction includesincludes a hollow-cylindrical support structure. A skirt is connected to the support structure and forms a closed, circumferential jacket of the support structure. The prosthesis also includes a valve leaflet arrangement with a first valve leaflet and a second valve leaflet, each being connected to the skirt. A downstream edge of the first valve leaflet and a downstream edge of the second valve leaflet are opposite to each other and configured in such a manner that in a first state of the valve leaflet arrangement they form an opening for blood to flow through in the predetermined direction and in a second state of the valve leaflet arrangement the opening is closed and to prevent a backflow of blood in a direction opposite to the predetermined direction. A ratio of the inner diameter of the support structure to its length in the predetermined direction is at most 1.

The present application provides a venous valve prosthesis, comprising a stent body and a valve; the stent body has an inner cavity, and the stent body comprises a proximal positioning part, a supporting part and a distal positioning part; the valve is connected to at least the supporting part and divides the inner cavity into a first segment and a second segment arranged from the proximal end to the distal end; the valve has a first position and a second position; the venous valve prosthesis is used for implanting into a target lumen for the target liquid to flow through; when the valve is subjected to a pressure from the target liquid pointing from the distal end to the proximal end, the valve is in the first position, so as to make the first segment and the second segment communicate to allow the target liquid to flow from the second segment into the first segment; when the valve is subjected to a pressure from the target liquid pointing from the proximal end to the second segment, the valve is in the second position, so as to make the first segment and the second segment isolated to prevent the target liquid from flowing from the first segment into the second segment. The venous valve prosthesis can be implanted into a venous vessel and replace a diseased venous valve, thereby preventing blood reflux.

This invention discloses a method for preparing a biogenic vein containing venous valves, belonging to the field of biomedical functional technology. The method includes the following steps: cutting a porcine or bovine jugular vein containing intact valves, cleaning, disinfecting, and rinsing it for later use; sequentially performing cell lysis, cell digestion, and nucleic acid digestion; then immersing it in a 1 mol / L hydroxylamine sulfate solution for heparin covalent cross-linking; and finally immersing it in a treatment solution to obtain a biogenic vein containing venous valves. The treatment solution is a PBS solution containing 4 wt% hydroxyethyl starch and 0.1 wt% polyhexamethylene biguanide. The method for preparing a biogenic vein containing venous valves provided by this invention significantly solves the technical problems of insufficient dehydration and antibacterial activity mentioned in the background art by introducing a treatment solution containing 4 wt% hydroxyethyl starch and 0.1 wt% polyhexamethylene biguanide during the preparation process. Simultaneously, the valve function of the biogenic vein is significantly improved.

The application discloses a kind of venous valve hydrogel scaffold material and its preparation method and application.This method uses polyethylene oxide and other viscoelastic non-Newtonian fluid capable of experiencing weissenberg effect as liquid soft template, when polyethylene oxide solution experiences weissenberg effect similar to valve structure, a layer of fast-crosslinking hydrogel material precursor is evenly covered on the liquid surface by spraying, so that the hydrogel is quickly crosslinked, and a venous valve hydrogel scaffold material is obtained.The application has the advantages of simple device, fast and convenient manufacturing method, adjustable venous valve scaffold material structure, etc., and can realize continuous manufacturing of venous valve hydrogel scaffold material with low cost.The application can promote the further development of valve-related physiology and pathology research.The prepared venous valve hydrogel scaffold material can realize the one-way flow function of venous valve, and can be used to construct an in-vitro venous valve model, so it has good medical application prospect.

The present application relates to a thrombectomy system, comprising a suction catheter, a blocking device and a stirring device, the suction catheter has a suction channel and a guide wire channel, the blocking device comprises a blocking catheter and a blocking device arranged at the distal end of the blocking catheter and having an open state and a folded state; the stirring device comprises a first sheath tube, a second sheath tube slidingly sleeved outside the first sheath tube, and a stirring assembly arranged at the distal end of the first sheath tube. The present application can remove a large amount of thrombus in the inferior vena cava in a relatively safe manner, protect the venous valve and the venous vessel wall, control the amount of blood loss, simplify the operation steps, shorten the operation time and reduce the hospitalization cost of the patient.

The invention discloses portable PICC intracavity electrocardio positioning integrated detection equipment, which relates to the technical field of electrocardio detection and comprises an integrated host module, a multi-mode positioning module and an intelligent analysis module, by integrating four positioning technologies of ultrasonic imaging, intracavity electrocardio, electromagnetic tracking and millimeter-wave radar and through a multi-source data fusion algorithm, submillimeter-level real-time positioning of the tip end of the catheter is achieved, and compared with traditional X-ray positioning, the positioning precision is higher, and the radiation influence can be effectively avoided; and motion artifacts are eliminated by adopting a nano-coating wireless lead technology and a self-adaptive filtering design, so that the stability of electrocardiosignals can be ensured, and meanwhile, venous valve sub-pixel level labeling is realized by combining a micro linear array probe with a blood vessel segmentation algorithm, so that the puncture guide efficiency is improved, and in conclusion, the method is suitable for popularization and application. Through multi-mode cooperation, intelligent decision and wireless interaction, the PICC catheterization operation time is greatly shortened, and the clinical safety and the operation standardization level are remarkably improved.