2329 results about "Isopropyl" patented technology

An environmentally clean dual fuel for an internal combustion engine, comprising acetylene as a primary fuel and a combustible fuel, such as one or more fluids selected from an alcohol such as ethanol, methanol or any other alcohol or alcohols from the group comprising C1-C20 carbon chains, ethers such as from the group comprising dimethyl ether, diethyl ether, methyl t-butyl ether, ethyl t-butyl ether, t-amyl methyl ether, di-isopropyl ether and the like, low-molecular-weight esters such as from the group comprising methyl formate, methyl acetate, ethyl acetate, methyl propionate, ethyl propionate and the like, or other suitable combustible fluid such as mineral spirits and the like, as a secondary fuel for operatively preventing early ignition and knock arising from the primary fuel. The dual fuel, internal combustion system, which generally utilizes a two-stage process for start-up and operation and can be operated with air- or liquid-cooling, is environmentally clean with hydrocarbon, CO, NOx, and SOx emissions substantially eliminated.

The present invention provides a compound of the formula: wherein ring A is an optionally substituted 5 to 10-membered aromatic ring; R¹ and R² are the same or different and each is an optionally substituted hydrocarbon group or an optionally substituted heterocyclic group; X is a bond and the like; and L is a divalent hydrocarbon group, and a salt thereof, except 3-(aminomethyl)-2,6,7-trimethyl-4-phenyl-1(2H)-isoquinolinone, 3-(aminomethyl)-2-methyl-4-phenyl-1(2H)-isoquinolinone, 3-(aminomethyl)-6-chloro-2-methyl-4-phenyl-1(2H)-isoquinolinone and 3-(aminomethyl)-2-isopropyl-4-phenyl-1(2H)-isoquinolinone. The compound shows a superior peptidase-inhibitory activity and is useful as an agent for the prophylaxis or treatment of diabetes and the like.

The invention relates to the technical field of preparation of environment functional materials, in particular to a magnetic composite material surface imprinting thermosensitive adsorbent, and a preparation method and the application thereof. The method comprises the following steps that: firstly, a ferroferric oxide/nerchinskite nanotube magnetic composite material is prepared by a solvent thermal synthesis method; secondly, the magnetic composite material is modified on ethenyl by using 3-(methacrylo) propyltrimethoxyl silane; and finally, the nerchinskite nanotube magnetic composite material is prepared by using the ethenyl-modified magnetic composite material as a substrate material, 2, 4, 5-trichlorophenol as a template molecule, methacrylate as a functional monomer, N-isopropylacrylamide as a thermosensitive functional monomer, ethylene glycol dimethacrylate as a cross-linking agent, and 2,2'-azodiisobutyronitrile as an initiator. The prepared thermosensitive imprinting adsorbent is obvious in thermal stability and magnetic stability, sensitive in magnetic effect and thermosensitive effect, relatively high in adsorption capacity, obvious in reversible absorption/release function along with temperature and obvious in tertiary calcium phosphate (TCP) molecule recognition performance.

Imidazolium salts are the immediate precursors to N-heterocyclic carbenes (NHC) yet a simple, general synthetic route to a wide variety of imidazolium salts is not yet available. Such a straightforward route is described for two specific members of this family of ligand precursor: 1,3-Bis(2,4,6-trimethylphenyl)imidazolium chloride (IMes.HCl) and 1,3-Bis(2,6-diispropylphenyl)imidazolium chloride (IPr.HCl). The procedure appears general and similar protocols can be used to isolate various imidazolium salts.

The invention discloses a method for floating high-sulfur gold-bearing copper ore, which aims at solving the problems that the existing beneficiation method is lower in copper and gold recovery rate under high-alkali condition, and problems that xanthate and black powder are adopted as high-sulfur gold-bearing copper ore collecting agents, the collecting power is stronger, the selectivity is poor, the separation difficulty of copper and sulfur can be aggravated and the consumption of inhibitors is increased. The method comprises the steps of by adopting lime and sodium metabisulfite as an ore pulp pH regulator and a pyrite inhibitor, and the mixture of isopropyl xanthogen propionitrile ester, black powder acid and ethyl dithiocarboxyl propionitrile ester according to certain proportion as a collecting foaming agent, carrying out ore grinding, rough concentration, primary scavenging, secondary scavenging, primary concentration, and secondary concentration on a crude ore, thus realizing the high-efficiency recovery on copper and gold in the high-sulfur gold-bearing copper ore. According to the method, through reasonable combination and addition of medicaments, the selective adsorption of the collecting agent on target mineral-copper pyrite and other copper sulfide minerals and gold minerals can be reinforced, and the copper recovery rate and the gold recovery rate can be improved.

The invention discloses a magnetic PAFs solid-phase extracting agent. A preparation method of the magnetic PAFs solid-phase extracting agent includes allowing 3-aminopropyl triethoxy silylation ferroferric oxide to have a temperature-programmed reaction with piperazine and cyanuric chloride in the presence of N, N-diisopropylethylamine to obtain the magnetic PAFs solid-phase extracting agent. The magnetic PAFs solid-phase extracting agent and the preparation method thereof have the advantages that the prepared magnetic PAFs solid-phase extracting agent is good in dispersity and stable in core-shell structure; the preparation method is simple, low in cost, widely applicable, capable of achieving repeated material recycling, and the like; a covalent organic framework bonded to the ferroferric oxide can provide various action sites such as an inclusion interaction site, a hydrogen-bond interaction site, a pi-pi interaction site and an anion exchange site, so that the covalent organic framework has specific recognition and retention acting force on polar substances such as phenols and carboxylic acids.

The present invention is directed to novel methods for production of 5-epi-β-vetivone, 2-isopropyl-6,10-dimethyl-spiro[4.5]deca-2,6-dien-8-one and 2-isopropyl-6,10-dimethyl-spiro[4.5]deca-1,6-dien-8-one, which are useful for their fragrant qualities. In one embodiment the present invention describes a method for production of 5-epi-β-vetivone by the use of premnaspirodiene as starting material. In another embodiment the present invention describes a method for production of 2-isopropyl-6,10-dimethyl-spiro[4.5]deca-2,6-dien-8-one and 2-isopropyl-6,10-dimethyl-spiro[4.5]deca-1,6-dien-8-one by the use of premnaspirodiene as starting material. In yet another embodiment the present invention describes a novel method for production of premnaspirodiene from a terpene substrate. Use of the fragrant components or any composition containing the component can be advantageously employed in the perfumery industry.

The invention relates to sulfonyl-containing 3,4-diaryl-3-pyrrolin-2-ones compounds having formula (I) wherein R1 is selected from the group consisting of 4-methylsulfonyl, 4-aminosulfonyl, hydrogen, 2-, 3-, or 4-halogen, C1-C6-alkyl, cyclopentyl, cyclohexyl, C1-C4-alkoxy, hydroxy, cyano, nitro, amino or trifluoromethyl; R2 is selected from the group consisting of 4-methylsulfonyl, 4-aminosulfonyl, hydrogen, 2-, 3-, or 4-halogen, C1-C6-alkyl, cyclopentyl, cyclohexyl, C1-C4-alkoxy, hydroxy, cyano, nitro, amino or trifluoromethyl; and R3 is selected from the group consisting of hydrogen, methyl, ethyl, n-propyl, i-propyl, c-propyl, n-butyl, isobutyl; provided that when R1 is a methylsulfonyl or aminosulfonyl group, R2 is any group as defined above except a methylsulfonyl or aminosulfonyl group; and when R2 is a methylsulfonyl or aminosulfonyl group, R1 is any group as defined above except a methylsulfonyl or aminosulfonyl group, also to processes for the preparation of such compounds, to pharmaceutical compositions containing such compounds, and to the medical use of such compounds in the treatment of diseases relating to the inhibition of cyclooxygenase-2 (COX-2).

A cooling topical cosmetic or dermatological preparation which comprises (1R,2S,5R)-2-isopropyl-5-methyl-N-(2-(pyridin-2-yl)ethyl)cyclohexane carboxamide and/or (1R,2S,5R)-N-(4-cyanomethyl-phenyl)-2-isopropyl-5-methylcyclohexane carboxamide, in combination with menthoxypropanediol.

The invention discloses a temperature-sensitive magnetic sulfadimidine molecular imprinted adsorbent as well as a preparation method and application thereof, belonging to the technical field of preparation of environment functional materials. A gamma-Fe2O3/SiO2 magnetic composite material is prepared by using a sol-gel method and is subjected to vinyl modification by using 3-(methylacryloyloxy) trimethoxypropylsilane; with a vinyl-modified magnetic composite material (MPS (Modified Polystyrene)-gamma-Fe2O3/SiO2) as a substrate material, sulfadimidine as a template molecule, acrylamide as a functional monomer, N-isopropylacrylamide as a temperature-sensitive monomer, ethylene glycol-bis(methylacrylic acid) ester as a cross-linking agent and 2,2'-azobisisobutyronitrile as an initiator, a temperature-sensitive magnetic molecular imprinted polymer is prepared by using a free group polymerization process and is applied to selective recognition and separation of the sulfadimidine in an aqueous solution; and the obtained polymer has the advantages of remarkable heat and magnet stability, sensitive magnet and heat inducting effect, higher adsorption capacity, reversible adsorption/release function along with the temperature and remarkable recognition performance of a sulfadimidine molecule.

The invention discloses a preparation method of a double-sensitivity cyclodextrin supermolecule aggregate, belonging to the technical field of functional materials. The preparation method comprises the following steps of preparing a host molecule-photosensitive 4-hydroxycinnamic acid-cyclodextrin (4HCA-CD) by using 4-hydroxycinnamic acid (4HCA) to modify beta-cyclodextrin (beta-CD); using trithioester with adamantine (AD) at tail end as a chain transfer agent, and preparing temperature-sensitive object polymer-double-arm adamantine-poly(N-isopropyl acrylamide)-adamantine (AD-PNIPAM-AD) by using a reversible addition-fragmentation chain transfer free radical polymerization (RAFT) method; constructing a double-sensitivity supermolecule inclusion complex 4HCA-CD/AD-PNIPAM-AD by utilizing comprehensive performance of a beta-CD dewatering cavity and AD; and self-assembling the 4HCA-CD/AD-PNIPAM-AD to form the supermolecule aggregate which is capable of realizing reversible conversion in shape and size by changing light and temperature. The supermolecule aggregate prepared by the preparation method disclosed by the invention has good light/temperature double sensitivities and is capable of carrying out smart response onto external stimulus, so that the supermolecule aggregate has a wide application prospect in the fields of drug loading, controlled release, and the like.

The invention discloses a method for preparing a hollow silica nanosphere by one step. The method comprises the following steps: mixing a poly-N-isopropyl acrylamide aqueous solution and an ethyl orthosilicate prehydrolysis solution at a temperature of 40 to 60 DEG C to react at a constant temperature for 160 to 180 hours; and carrying out ethanol washing, ultrasonic concussion, centrifugal separation and drying on a reaction liquid, and then obtaining the hollow silica nanosphere. The hollow silica nanosphere has a hollow core and mesoporous shell structure, the particle diameter is between 200 and 600 nm, and the shell thickness is between 30 and 100 nm. The invention also discloses the hollow silica nanosphere and the application. The method does not need to use an organic solvent to catalyze or further remove a template agent by high-temperature calcination or chemical corrosion, and can control the hollow nanosphere size and the shell thickness by simply changing the reaction temperature, the reaction time and the feed ratio.

A topical cosmetic and dermatological preparation for reducing skin reddening which comprises (1R,2S,5R)-2-isopropyl-5-methyl-N-(2-(pyridin-2-yl)ethyl)-cyclohexane carboxamide and/or (1R,2S,5R)—N-(4-cyanomethyl-phenyl)-2-isopropyl-5-methylcyclohexane carboxamide.

The invention relates to a thermo-sensitive poly N-isopropylacrylamide/polyurethane medicine-loading electro-spun fibrous membrane and a preparation method thereof, relating to a medicine-loading electro-spun fibrous membrane and a preparation method thereof and aiming to solve problems of poor mechanical property of existing poly N-isopropylacrylamide medicine-loading electro-spun fibrous membrane and no temperature sensitivity of a polyurethane medicine-loading electro-spun fibrous membrane. The thermo-sensitive poly N-isopropylacrylamide/polyurethane medicine-loading electro-spun fibrous membrane is prepared by poly N-isopropylacrylamide, polyurethane, N,N-dimethylformamide and a medicine; the preparation method comprises the following steps: 1, preparing static spinning solution; 2, dissolving the medicine so as to obtain the static spinning solution containing the medicine; 3, carrying out electrospinning; and 4, carrying out dry treatment to obtain the thermo-sensitive poly N-isopropylacrylamide/polyurethane medicine-loading electro-spun fibrous membrane. According to the invention, the preparation method is mainly used for preparing the thermo-sensitive poly N-isopropylacrylamide/polyurethane medicine-loading electro-spun fibrous membrane.

Provided is a pharmaceutical preparation for treatment or prevention of glaucoma or ocular hypertension, comprising 0.0003 to 0.01% (w/v) of isopropyl(6-{[4-(pyrazol-1-yl)benzyl](pyridin-3-ylsulfonyl)aminomethyl}pyridin-2-ylamino)acetate, or a salt thereof.

The invention relates to poly-N- isopropyl acrylamide-poly-amino acid two section copolymer and the manufacturing method. It is made from poly-N-isopropyl acrylamide that the equal molecular weight is 1000-10000. The poly-amino acid is poly-L-glutamic acid or poly-L- aspartic acid that the equal molecular weight is 1000-30000. The copolymer has double responsibility to temperature and pH in water solution. The pH responding range would alter around the content of benzyl group in poly-amino acid. And it could take biodegradation. The invention could be used as carrier that the in vivo target released to medicine and could be used as injectable intelligent responding hydrogel.