1029 results about "Sea cucumber" patented technology

The invention discloses a sea cucumber protein heptapeptide with functions of reducing blood pressure and blood sugar and application of the sea cucumber protein heptapeptide, and belongs to the technical field of bioactive peptide biology. The amino acid sequence of the sea cucumber protein heptapeptide is LPPGPFP. The sea cucumber protein heptapeptide can significantly inhibit the activity of ACE through a competitive inhibition mode, tolerates the gastrointestinal tract digestion environment, also has DPP-IV inhibition activity, can relieve hypertension and type 2 diabetes mellitus at the same time, and has an application value in preparation of products with the efficacy of reducing blood pressure and blood sugar due to multiple functions of the sea cucumber protein heptapeptide. The sea cucumber protein heptapeptide provided by the invention can significantly inhibit the activity of ACE through a competitive inhibition mode, has DPP-IV inhibition activity, has the characteristics of simple structure, safety, strong activity and the like, and has a wide application prospect.

An underwater in-situ sea cucumber volume measurement method based on binocular vision and electronic equipment belong to the field of image processing, are used for solving the problem of keeping in-situ sea cucumber volume measurement, and are technically characterized in that a sea cucumber image is detected in underwater images collected by a binocular camera to obtain a sea cucumber image detection frame; segmenting a sea cucumber image detected in the image according to the sea cucumber image detection frame, and calculating mask information of the sea cucumber on an image plane; mapping the mask information to a global point cloud constructed by binocular information, and obtaining point cloud data of the sea cucumber; performing grid reconstruction on the point cloud data of the sea cucumber to obtain a continuous triangular grid; according to the method, the continuous triangular grids are converted into voxel representation, the number of non-zero elements in the voxel grids and the volume of each element are counted, the volume of the grids is estimated, and the volume of the sea cucumbers is obtained, so that the volume of the in-situ sea cucumbers can be accurately evaluated, and more accurate data support is provided for scientific cultivation of the sea cucumbers.

The invention provides a sea cucumber total nutrient extract production quality traceability method based on whole process tracking, and relates to the technical field of production quality traceability, and the method comprises the following steps: sampling a sea cucumber total nutrient extract in a finished product stage; carrying out key quality index detection on a plurality of sample extracts; obtaining a process-index degree matrix; positioning H risk process nodes; performing optimization hierarchical classification on the H risk process nodes according to the H risk contribution degrees and the standard process; and performing multi-level progressive optimization of the sea cucumber extraction process on the H risk process nodes, and performing process parameter updating by adopting a process optimization result. According to the method and the device, the technical problem of difficulty in production quality tracing caused by difficulty in real-time tracking of quality data in the whole production process due to the fact that data of each production link is usually isolated in the prior art can be solved, and the production quality tracing efficiency is improved by tracking the whole process from the production raw materials to the final product quality. And the transparency and traceability of the production quality are improved.

The invention relates to a sea cucumber growth character recognition and measurement method based on machine vision and a measurement system thereof, and belongs to the field of image processing, and the method comprises the following steps: S1, image acquisition and preprocessing; s2, instance segmentation and morphological feature extraction; s3, measuring the length and width of the sea cucumber; s4, pixel-to-actual size conversion is carried out; s5, constructing a body weight prediction model; and S6, outputting a result. The method has the advantages that the sea cucumber image is obtained by using the high-definition image acquisition technology, the contour information of the sea cucumber is accurately extracted through the instance segmentation algorithm, and the problems of changeable and irregular sea cucumber shapes and the like are effectively solved by combining the optimized image processing technology, so that the measurement precision is remarkably improved. Meanwhile, a machine learning regression model is introduced, the weight of the sea cucumber is predicted based on various morphological characteristics, and the dimensionality and the utilization value of measured data are further enriched.

The invention discloses a green processing technology of sea cucumber powder capable of realizing directional enrichment and improving polysaccharide release rate, and belongs to the field of food processing. The sea cucumber powder is prepared by the following steps: S1, pretreating sea cucumbers; s2, enrichment of nutrient substances of the sea cucumbers; s3, regulating and controlling the particle size of the sea cucumber powder; s4, performing'single 'supercritical treatment; s5, carrying out in-situ ultramicro physical crushing; and S6, performing'dual 'supercritical treatment. Through the design of the gas disperser and the additional arrangement of the second hole disc, the supercritical extraction instrument can perform effective supercritical carbon dioxide extraction on the ultramicro sea cucumber powder, the deodorization of the ultramicro sea cucumber powder is realized, and the eating quality of the ultramicro sea cucumber powder is improved. Moreover, by detecting and regulating the stacking density and the tap density, optimal processing parameters for the ultramicro sea cucumber powder are found, so that the prepared ultramicro sea cucumber powder is high in polysaccharide release rate, good in eating quality and easy for subsequent processing.

The invention discloses sea cucumber gonad-derived antioxidant peptide as well as a preparation method and application thereof, and belongs to the technical field of food biology. The antioxidant peptide is obtained by carrying out enzymolysis and molecular docking screening on sea cucumber gonads, and comprises at least one of peptides with amino acid sequences as shown in SEQ.ID.NO.1-4. Wherein the docking energy of the SEQ.ID.NO.1 and the receptor SOD is-7.5 kcal / mol, the docking energy of the SEQ.ID.NO.2 and the receptor SOD is-7.5 kcal / mol, the docking energy of the SEQ.ID.NO.3 and the receptor SOD is-7.4 kcal / mol, and the docking energy of the SEQ.ID.NO.4 and the receptor SOD is-7.2 kcal / mol. Tests prove that the antioxidant peptide has high antioxidant activity and has wide application space in the field of functional food.

The invention belongs to the technical field of health-care products, and particularly relates to a fermented composition beneficial to enhancing immunity and a preparation method thereof. The fermentation composition for improving immunity is prepared by taking yeast beta-glucan, an elderberry extract, glucoraphanin, sea cucumber peptide, inulin and a traditional Chinese medicine zymolyte as fermentation raw materials, firstly inoculating bacillus coagulans and staphylococcus xylosus for aerobic fermentation, and then inoculating bifidobacterium longum for anaerobic fermentation, the aerobic fermentation stage and the anaerobic fermentation stage have a synergistic effect, so that the fermentation speed can be increased, the fermentation time can be shortened, and richer nutrient substances can be provided, and therefore, the composition has an excellent effect of enhancing the immunity; the fermentation composition is applied to preparation of capsules helpful for enhancing immunity, is helpful for enhancing human immunity, and can solve the problem that active substances in existing health-care products are difficult to effectively absorb by human bodies, so that the effect of enhancing immunity is influenced.

The invention belongs to the technical field of aquaculture, and particularly relates to a liftable holothurian culture device which comprises a culture box. A pair of fixing frames is arranged on the side wall of the breeding box, hollow grooves are formed in the fixing frames, multiple groups of water inlet holes communicated with the hollow grooves are formed in the top surfaces of the fixing frames, and sealing mechanisms for sealing the water inlet holes are arranged on the fixing frames; a connecting groove is formed in the bottom surface of the breeding box; when the culture box needs to ascend, the sealing mechanism does not seal the water inlet hole any more, seawater enters a hollow groove from the water inlet hole to push a sliding plate, and meanwhile, a first spring pushes the sliding plate, so that gas in the hollow groove enters an elastic block through a gas inlet pipe under the pushing of the sliding plate, the elastic block is inflated and expanded, and the water inlet hole is opened; after the elastic block expands to a certain degree, the sealing assembly does not seal the end opening of the connecting groove any more, at the moment, the elastic block can make contact with seawater, and therefore the culture box is driven to ascend by means of buoyancy.

The invention relates to application of sea cucumber-derived nano-vesicles in preparation of a medicine for promoting wound repair. The nano-vesicles (SC-EVs) extracted and prepared from sea cucumbers can effectively promote cell migration, scratch repair and tube forming capabilities of human skin epithelial cells (HACAT) and human skin microvascular endothelial cells (HM DEC) and inhibit cell apoptosis, so that the capability of repairing cells is achieved, and particularly the effect of repairing wound surfaces in a high glucose state or diabetes mellitus is achieved. The invention provides a new direction and thought for the application of the sea cucumber-sourced nano vesicles (SC-EVs), provides a brand new drug research and development and clinical treatment direction for wound repair, especially for solving the problem of difficult healing of wounds of patients with high glucose or diabetes, and has extremely high social value and market application prospect.

The invention discloses a green deodorization method suitable for ultramicro sea cucumber powder, and belongs to the field of food processing. The method comprises the following steps: S1, putting sea cucumber coarse powder into an extraction kettle of a supercritical extraction instrument, and deodorizing the sea cucumber powder; s2, crushing the sea cucumber powder subjected to fishy smell removal in the step S1 by using an ultrafine crusher to obtain sea cucumber powder, and controlling the bulk density of the powder to be 0.65-0.7 g / mL and the tap density to be 0.70-0.80 g / mL; and S3, putting the sea cucumber powder subjected to superfine grinding in the step S2 into an extraction kettle of a supercritical extraction instrument for deodorization. According to the invention, the second hole disc is additionally arranged on the gas distributor in the supercritical extraction instrument, so that carbon dioxide fluid flows back during extraction, the pressure of the carbon dioxide fluid discharged from the material basket is reduced, and the material is prevented from being taken out, thereby solving the problem of pipeline blockage of ultra-micro powder and improving the extraction efficiency and the production efficiency.

The invention relates to an application of sea cucumber intestine polysaccharide in preparation of uric acid lowering drugs. The preparation method of the sea cucumber intestine polysaccharide comprises the following steps: performing enzymolysis treatment on sea cucumber intestines by using papain, performing enzyme deactivation, performing centrifugation, and taking supernate; and carrying out graded alcohol precipitation on the supernate, centrifuging, taking precipitate, deproteinizing and freeze-drying. The preparation method is simple, green and environment-friendly. The sea cucumber intestine polysaccharide prepared by the method can effectively inhibit the activity of xanthine oxidase; the sea cucumber intestine polysaccharide has no toxic effect on HK-2 cells. The compound has a uric acid reducing effect on HK-2 hyperuricemia cells.

The invention discloses a preparation method and application of a sea cucumber exosome with an immune cell repairing function, and belongs to the technical field of biomedicine. The method comprises the following steps: feeding sea cucumbers by using a combined method of composite stress and an echinacea extract, extracting sea cucumber cells, and obtaining sea cucumber exosomes through ultracentrifugation; wherein the condition of composite stress is set as follows: the day and night temperature difference is not lower than 3 DEG C, and meanwhile, the dissolved oxygen content of the water body is adjusted to 75-90% of the dissolved oxygen content of the conventional feeding water body. The obtained sea cucumber exosome has a remarkable immune cell repairing function, and can effectively promote proliferation and activity recovery of immune cells, inhibit expression of inflammatory factors and improve the level of anti-inflammatory factors. The sea cucumber exosome prepared by the preparation method disclosed by the invention has an important application prospect in the research and development of immune repair drugs, and can provide a technical support for a novel immune regulation preparation in the field of biomedicine.

The invention relates to the technical field of abalone peptide production, and discloses extraction equipment for extracting natural taurine from sea cucumbers, which solves the problems of function splitting, pollution transfer and low efficiency in the traditional process by integrating three functional modules of countercurrent stirring, in-situ filtration and rotary elution. A reverse stirring part forms shear convection through stirring blades rotating in two directions and a stirring plate, and sea cucumber tissue breaking is accelerated; a dynamic adjusting and filtering mechanism is adopted in the filtering part, filtering modes are switched after stirring, and in-situ separation of the extracting solution and the raw materials is achieved; the elution part drives the cationic resin to be in forced contact with an extracting solution through rotation, and the adsorption efficiency is improved by combining through-channel type resin distribution. The three components cooperatively operate in a single tank, and traditional crushing, extracting, separating and eluting multi-step processes are integrated into a continuous flow. The method has the advantages that the extraction efficiency is improved, the taurine purity is improved, and meanwhile, the material transfer loss and the pollution risk are reduced.

The invention discloses a sea cucumber peptide as well as a preparation method and application thereof, and belongs to the technical field of biology. The sea cucumber peptide has an anti-photoaging effect and is composed of any one or two of the following polypeptides: the amino acid sequence of the polypeptide I is SPQTPGSP, and the amino acid sequence of the polypeptide II is DLVVVK. Researches find that the sea cucumber peptide is high in activity, good in biocompatibility, safe and free of toxic and side effects, has good anti-photoaging activity, and can be used for preparing anti-photoaging products, especially cosmetics.

The invention discloses a buoyant raft net cage holothurian culture device and a holothurian culture method. The buoyant raft net cage holothurian culture device comprises a net cage main body, a bait enrichment device and a bait slow release device, the interior of the net cage body is used for containing sea cucumbers. The bait enrichment device is arranged in the net cage main body and comprises at least one deposition structure; the bait slow-release device is arranged in the net cage body and used for controlling the release rate and distribution of bait. According to the novel buoyant raft net cage holothurian culture device and the matched culture method, bait loss can be effectively reduced, the bait utilization rate is increased, and therefore the growth speed and breeding efficiency of holothurian are improved.

The utility model discloses a sea cucumber enzymolysis device, which relates to the technical field of sea cucumber processing, and comprises a tank body, a mixing mechanism is arranged at the top of the tank body, a filtering mechanism is arranged at the bottom of the tank body, the mixing mechanism comprises two electric telescopic rods and a material barrel, the two electric telescopic rods are arranged outside the tank body, and the material barrel is arranged in the tank body. The material barrel is movably installed in the tank body, top blocks are installed at the top ends of the electric telescopic rods, rotating shafts are installed between the inner sides of the two top blocks and the positions, close to the top ends, of the periphery of the material barrel, a motor is installed at the top of the material barrel, and a stirring rod is installed at the position, located in the material barrel, of the bottom end of an output shaft of the motor. A first screw groove is formed in the inner wall, close to the bottom end, of the material barrel; the sea cucumber raw materials can be conveniently added and taken out, the sea cucumber raw materials are separated from the stock solution, the utilization rate of the sea cucumber raw materials is increased, meanwhile, the stock solution can be further filtered, and impurities in the stock solution are reduced.

The invention discloses an easily-occurring sea cucumber processing control method and system based on oxygen injection synergistic hydrotherapy, relates to the technical field of food processing control, and realizes self-adaption and precise control of a sea cucumber processing process through multi-sensor feedback. The method comprises the following steps: firstly, calling a processing technology parameter vector X of a sea cucumber variety to carry out standardization setting, and calculating the maximum oxygen introduction amount OMAX to carry out pretreatment so as to mildly wake up tissues; and then the real-time water turbidity Trt is monitored until the cleaning threshold TMIN is reached, so that deep cleaning is completed. In the secondary hydrotherapy, the real-time oxygen introduction amount Ort is dynamically adjusted to maintain the target dissolved oxygen concentration DO2 of the secondary hydrotherapy, and the processing environment is stabilized. And monitoring the real-time conductivity Crt of the secondary hydrotherapy solution, and ending the conditioning when the change value C of the real-time conductivity of the secondary hydrotherapy solution meets the requirement, thereby realizing the intelligent judgment of the absorption process. And finally, processing is completed after preset standing time tP, and uniform quality is ensured.

The invention discloses sea cucumber peptide, a preparation method, a composition and application, and relates to the technical field of biology. The sea cucumber peptide has the effect of preventing and / or treating alcoholic liver injury and comprises a first polypeptide, a second polypeptide and a third polypeptide, the amino acid sequence of the first polypeptide is ALKTPDK, the amino acid sequence of the second polypeptide is LEREDGPEVTVI, and the amino acid sequence of the third polypeptide is TGVDNPGHP. The sea cucumber peptide is high in activity, good in biocompatibility, safe and free of toxic and side effects, has good activity of preventing and / or treating alcoholic liver injury, and can be used for preparing products for preventing and / or treating alcoholic liver injury.

The utility model discloses a sea cucumber fishing robot. Comprising a robot moving chassis, the chassis is integrated with a sealed cabin, and the sealing performance and safety of the robot are ensured; the mechanical arm device and the collecting device are arranged at the top of the movable chassis, and joint drivers of the mechanical arm device are waterproof steering engines, specifically, a shoulder joint double-shaft steering engine, a shoulder joint single-shaft steering engine, an elbow joint double-shaft steering engine, a wrist joint double-shaft steering engine, a wrist joint single-shaft steering engine and a clamping jaw driving steering engine; the rotation of each part of the mechanical arm and the closing and opening of the clamping jaw are realized by controlling each steering engine; meanwhile, the camera at the tail end of the clamping jaw transmits pictures to corresponding operators in real time, and the sea cucumbers are grabbed through remote control. The sea cucumber fishing device can comprehensively replace a traditional manual fishing mode, is not limited by seasons, and ensures that sea cucumbers are caught continuously all the year round. Water pressure far exceeding human beings can be borne, the operation safety is remarkably improved, and potential hazards of the marine environment to the body health of fighters are effectively avoided.

The invention relates to a preparation method of small-molecular-weight sea cucumber oligopeptide, the prepared sea cucumber oligopeptide and application, and belongs to the technical field of skin care products. The preparation method of the small-molecular-weight sea cucumber oligopeptide comprises the following steps: preparing sea cucumber fine powder; adding the sea cucumber fine powder into ultrapure water, adding papain and EDTA (Ethylene Diamine Tetraacetic Acid), and carrying out enzymolysis under the assistance of microwaves; adding trypsin and calcium ions, and carrying out enzymolysis under the assistance of microwaves; adding neutral protease and zinc ions, and performing enzymolysis under the assistance of microwaves to obtain final sea cucumber enzymatic hydrolysate; and decolorizing, separating and purifying, and freeze-drying to obtain the powdery small-molecular-weight sea cucumber oligopeptide. According to the preparation method of the small-molecular-weight sea cucumber oligopeptide, microwave heating and enzymolysis reaction are combined, the hydrolysis degree of a peptide chain is regulated and controlled by controlling an enzyme hydrolysis sequence and enzymolysis conditions, the small-molecular-weight sea cucumber oligopeptide with relatively concentrated and moderate molecular weight is prepared, and good biological activity of the sea cucumber oligopeptide is kept.

The invention belongs to the technical field of preparation of sea cucumber peptides, relates to preparation of sea cucumber small molecule peptides, and relates to a preparation method of sea cucumber peptides with composite effects of protecting liver and preventing liver cirrhosis, and the sea cucumber peptides with various effects are prepared by using fresh and alive sea cucumbers as raw materials through protease hydrolysis, fishy smell removal, deodorization and other processes. The sea cucumber peptide has the advantages of good solubility, good stability, low viscosity and the like. Compared with the transportation function of amino acid, the sea cucumber active oligopeptide has the characteristics of quick absorption, low consumption and difficulty in saturation, can be added into food, health food, medicine and the like, and has the effects of supplementing nutrition, protecting the liver function, preventing liver cirrhosis, supplementing mineral substances, protein and vitamins and the like.

The invention belongs to the technical field of preparation of biological materials, and particularly discloses a sea cucumber flower self-assembled polypeptide-iron nano-carrier as well as a preparation method and application of the sea cucumber flower self-assembled polypeptide-iron nano-carrier. The preparation method comprises the following steps: dissolving freeze-dried sea cucumber flower powder in deionized water, adjusting the pH value to be alkaline, heating and stirring, centrifuging, discarding the precipitate, adjusting the pH value to be acidic, centrifuging, collecting the precipitate, and freeze-drying to obtain sea cucumber flower protein powder; preparing a reaction solution, adding simulated gastric juice and simulated intestinal juice, stirring for reaction, inactivating protease, centrifuging, taking supernatant, and freeze-drying to obtain sea cucumber flower self-assembled polypeptide; the preparation method comprises the following steps: preparing a solution from sea cucumber, adding FeCl2. 4H2O and ascorbic acid, adjusting the pH value to be acidic, carrying out heating reaction, centrifuging, discarding the supernatant, and freeze-drying to obtain the sea cucumber flower self-assembled polypeptide-iron nano-carrier. The invention discloses a sea cucumber flower self-assembled polypeptide-iron nano-carrier as well as a preparation method and application thereof. The carrier can promote absorption of an organism to iron, a relatively high iron ion release rate is maintained in an intestinal environment, and the in-vivo bioavailability of iron ions is improved.

The invention relates to the technical field of preparation methods of giant salamander peptide and eucommia ulmoides male flower tablets, in particular to a preparation method of giant salamander peptide and eucommia ulmoides male flower tablets. The giant salamander peptide and eucommia ulmoides male flower tablets comprise the following raw materials in parts by weight: 30-40 parts of giant salamander peptide powder, 20-25 parts of eucommia ulmoides male flowers, 10-15 parts of rape pollen, 10-15 parts of sea cucumber intestine peptide powder, 10-12 parts of a filler, 3-5 parts of an adhesive and 1-3 parts of a lubricant. According to the invention, the eucommia male flower contains geniposidic acid, chlorogenic acid, aucubin lignin, iridoid and phenylpropanoid natural active nutrient substances, flavonoid compounds, polysaccharide and other bioactive substances in the rape pollen, polysaccharide and peptide components in the sea cucumber intestine peptide powder, and the like. The andrias davidianus peptide powder is added into the andrias davidianus peptide powder, the andrias davidianus peptide powder cooperates with antioxidant peptide and immunomodulatory peptide in the andrias davidianus peptide powder to jointly form a rich bioactive substance library, and the components regulate the physiological functions of the human body from different angles, provide comprehensive nutrition support for the body and improve the fatigue resistance of the human body.

The invention relates to the technical field of medical care, and particularly discloses a preparation method and application of sea cucumber peptide. The preparation method of the sea cucumber peptide provided by the invention comprises the following steps: heating sea cucumber primary pulp for denaturation, and then adding compound protease for enzymolysis treatment to obtain sea cucumber enzymatic hydrolysate; the addition amount of the compound protease is 0.1-0.15 mg / mL, and the compound protease is prepared from papain, ficin and trypsin according to the weight ratio of 1: (0.5-1.5): (2-3); adding activated carbon and diatomite into the sea cucumber enzymatic hydrolysate, and performing enzyme deactivation, filtration and concentration treatment to obtain sea cucumber peptide; the invention also provides application of the sea cucumber peptide obtained by the preparation method in medicines and foods. According to the preparation method of the sea cucumber peptide, the sea cucumber peptide with small molecular weight and good uniformity can be obtained, and the prepared sea cucumber peptide tablet candy has the effects of relieving physical fatigue, resisting aging, resisting oxidation and the like.

The invention belongs to the technical field of food biology, and particularly relates to sea cucumber gonad-derived anti-inflammatory peptide as well as a preparation method and application thereof. The anti-inflammatory peptide is obtained by performing enzymolysis and molecular docking screening on sexual glands of sea cucumbers, and comprises at least one of peptides with amino acid sequences as shown in SEQ.ID.NO.1-3. Experiments prove that the anti-inflammatory peptide has high anti-inflammatory activity, provides a basis for preparing functional food from natural food sources, and has important significance for development of novel anti-inflammatory products.

The invention relates to protein peptide and polysaccharide efficient separation equipment for sea cucumber peptide processing and a use method of the protein peptide and polysaccharide efficient separation equipment, and particularly relates to the technical field of bioengineering. The sea cucumbers are subjected to two-time enzymolysis by adopting two-time enzyme adding and two-time different hydrolase adding in cooperation with different enzymolysis conditions, a first ultrafiltration membrane with the molecular weight cut-off of 10 KDa is selected for first-time ultrafiltration separation, permeate liquid is protein peptide mixed liquid, cut-off liquid is polysaccharide mixed liquid, and the protein peptide mixed liquid and the polysaccharide mixed liquid are mixed. The protein peptide mixed solution and the polysaccharide mixed solution correspondingly enter corresponding ultrafiltration assemblies to be subjected to multi-stage ultrafiltration, protein peptide and polysaccharide are further separated and purified respectively, and finally the protein peptide mixed solution and the polysaccharide mixed solution enter corresponding spray drying towers to be subjected to spray drying to obtain corresponding protein peptide powder and polysaccharide powder; separation, purification and drying of protein peptide and polysaccharide can be achieved at the same time, and waste of resources is reduced.

The invention discloses a sea cucumber flower self-assembled polypeptide-selenium nano-carrier with antioxidant activity and a preparation method and application thereof, belongs to the technical field of functional protein peptides, and particularly relates to a preparation method of the sea cucumber flower self-assembled polypeptide-selenium nano-carrier with antioxidant activity, which comprises the following steps: heating a sea cucumber flower protein solution; the preparation method comprises the following steps: mixing sea cucumber with simulated gastric juice, reacting for 30-150 minutes, then adding simulated intestinal juice, reacting for 20-120 minutes, carrying out enzyme deactivation treatment, centrifuging, taking supernate, and freeze-drying to obtain sea cucumber flower self-assembled polypeptide; and mixing the sea cucumber flower self-assembled polypeptide with deionized water to prepare a sea cucumber flower self-assembled polypeptide solution, mixing the sea cucumber flower self-assembled polypeptide solution with a sodium selenite solution and a phosphate buffer solution, reacting for 20-60 minutes, washing with an ethanol solution, centrifugally collecting precipitate, and freeze-drying to obtain the sea cucumber flower self-assembled polypeptide-selenium nano-carrier. The sea cucumber flower self-assembled polypeptide-selenium nano-carrier prepared by the invention has good antioxidant activity and potential of effectively delivering selenium to an organism.

The invention discloses an active exosome stent coating based on traditional Chinese medicine enhanced secretion promotion and a preparation method and application thereof, and belongs to the technical field of biological medicine and interventional instruments. The stent coating comprises exosomes, wherein the exosomes comprise myocardial cell active exosomes and human mesenchymal stem cell active exosomes which are intensified and secreted by traditional Chinese medicines; wherein the traditional Chinese medicines comprise placenta extract, pilose antler extract, sheep myocardial peptide, sea cucumber peptide, lycium ruthenicum peptide, cnidium lactone, curculigo orchioides extract and morinda officinalis extract; the intervention concentration of each component added into cells is 2-50 [mu] g / mL; the light-cured gel matrix is prepared from methacrylated gelatin, a photoinitiator and polyether 127; tacrolimus; the final concentration of the exosome is 1 * 10 < 9 >-12 * 10 < 9 > particles / mL, and the final concentration of the tacrolimus is 5-25 mu g / mL. The coating can be coated on the surface of the poly-L-lactic acid degradable stent to prepare the degradable stent, and has obvious vascular repair promoting capability.

The invention relates to the technical field of marine product processing and application, and discloses a sea cucumber soaking method and a soaking state prediction method. Spreading the selected dried sea cucumbers and steaming for 30 minutes; soaking the steamed dried sea cucumbers in an ice-water mixture for 20 hours; cleaning the sea cucumbers soaked for 20 hours, removing internal organs, and cooking for 3 hours; and putting the sea cucumbers boiled for 3 hours into the ice-water mixture, and continuously soaking for 48 hours. The soaking state prediction method comprises the following steps: acquiring sea cucumber samples in different soaking states, measuring state indexes, and inputting the state indexes into a pre-constructed XgBoost model for prediction to obtain a sea cucumber soaking state prediction result. According to the method, each soaking link can be better controlled, the problem of unstable product quality is effectively solved, the soaking state of the sea cucumber is more objectively and accurately predicted, and the prediction accuracy is improved.

The invention discloses scallion braised sea cucumber processing and sampling equipment, and relates to the technical field of sampling, the scallion braised sea cucumber processing and sampling equipment comprises a fixed bottom table, the fixed bottom table is provided with a height control mechanism, the height control mechanism is connected with a lifting round block, the lifting round block is provided with a rotary displacement ring mechanism, and the outer side of the rotary displacement ring mechanism is provided with a mounting ring mechanism; the mounting ring mechanism is provided with a plurality of sampling assemblies, each sampling assembly comprises a deflection mounting mechanism, a sampling barrel mechanism and a liquid separation mechanism, the rotary displacement ring mechanism is provided with a driving ring mechanism, and a lifting circular block is fixedly connected with a deflection pressing plate mechanism. And the positions of the sampling assemblies can be adjusted by rotating the displacement ring mechanism, and the sampling assemblies meeting the required number can be mounted through the mounting ring mechanism, so that the material extraction efficiency is improved.