740 results about "Sea cucumber" patented technology

The invention relates to a sea cucumber growth character recognition and measurement method based on machine vision and a measurement system thereof, and belongs to the field of image processing, and the method comprises the following steps: S1, image acquisition and preprocessing; s2, instance segmentation and morphological feature extraction; s3, measuring the length and width of the sea cucumber; s4, pixel-to-actual size conversion is carried out; s5, constructing a body weight prediction model; and S6, outputting a result. The method has the advantages that the sea cucumber image is obtained by using the high-definition image acquisition technology, the contour information of the sea cucumber is accurately extracted through the instance segmentation algorithm, and the problems of changeable and irregular sea cucumber shapes and the like are effectively solved by combining the optimized image processing technology, so that the measurement precision is remarkably improved. Meanwhile, a machine learning regression model is introduced, the weight of the sea cucumber is predicted based on various morphological characteristics, and the dimensionality and the utilization value of measured data are further enriched.

The invention discloses sea cucumber gonad-derived antioxidant peptide as well as a preparation method and application thereof, and belongs to the technical field of food biology. The antioxidant peptide is obtained by carrying out enzymolysis and molecular docking screening on sea cucumber gonads, and comprises at least one of peptides with amino acid sequences as shown in SEQ.ID.NO.1-4. Wherein the docking energy of the SEQ.ID.NO.1 and the receptor SOD is-7.5 kcal / mol, the docking energy of the SEQ.ID.NO.2 and the receptor SOD is-7.5 kcal / mol, the docking energy of the SEQ.ID.NO.3 and the receptor SOD is-7.4 kcal / mol, and the docking energy of the SEQ.ID.NO.4 and the receptor SOD is-7.2 kcal / mol. Tests prove that the antioxidant peptide has high antioxidant activity and has wide application space in the field of functional food.

The invention belongs to the technical field of health-care products, and particularly relates to a fermented composition beneficial to enhancing immunity and a preparation method thereof. The fermentation composition for improving immunity is prepared by taking yeast beta-glucan, an elderberry extract, glucoraphanin, sea cucumber peptide, inulin and a traditional Chinese medicine zymolyte as fermentation raw materials, firstly inoculating bacillus coagulans and staphylococcus xylosus for aerobic fermentation, and then inoculating bifidobacterium longum for anaerobic fermentation, the aerobic fermentation stage and the anaerobic fermentation stage have a synergistic effect, so that the fermentation speed can be increased, the fermentation time can be shortened, and richer nutrient substances can be provided, and therefore, the composition has an excellent effect of enhancing the immunity; the fermentation composition is applied to preparation of capsules helpful for enhancing immunity, is helpful for enhancing human immunity, and can solve the problem that active substances in existing health-care products are difficult to effectively absorb by human bodies, so that the effect of enhancing immunity is influenced.

The invention relates to an application of sea cucumber intestine polysaccharide in preparation of uric acid lowering drugs. The preparation method of the sea cucumber intestine polysaccharide comprises the following steps: performing enzymolysis treatment on sea cucumber intestines by using papain, performing enzyme deactivation, performing centrifugation, and taking supernate; and carrying out graded alcohol precipitation on the supernate, centrifuging, taking precipitate, deproteinizing and freeze-drying. The preparation method is simple, green and environment-friendly. The sea cucumber intestine polysaccharide prepared by the method can effectively inhibit the activity of xanthine oxidase; the sea cucumber intestine polysaccharide has no toxic effect on HK-2 cells. The compound has a uric acid reducing effect on HK-2 hyperuricemia cells.

The invention discloses a preparation method and application of a sea cucumber exosome with an immune cell repairing function, and belongs to the technical field of biomedicine. The method comprises the following steps: feeding sea cucumbers by using a combined method of composite stress and an echinacea extract, extracting sea cucumber cells, and obtaining sea cucumber exosomes through ultracentrifugation; wherein the condition of composite stress is set as follows: the day and night temperature difference is not lower than 3 DEG C, and meanwhile, the dissolved oxygen content of the water body is adjusted to 75-90% of the dissolved oxygen content of the conventional feeding water body. The obtained sea cucumber exosome has a remarkable immune cell repairing function, and can effectively promote proliferation and activity recovery of immune cells, inhibit expression of inflammatory factors and improve the level of anti-inflammatory factors. The sea cucumber exosome prepared by the preparation method disclosed by the invention has an important application prospect in the research and development of immune repair drugs, and can provide a technical support for a novel immune regulation preparation in the field of biomedicine.

The invention relates to the technical field of abalone peptide production, and discloses extraction equipment for extracting natural taurine from sea cucumbers, which solves the problems of function splitting, pollution transfer and low efficiency in the traditional process by integrating three functional modules of countercurrent stirring, in-situ filtration and rotary elution. A reverse stirring part forms shear convection through stirring blades rotating in two directions and a stirring plate, and sea cucumber tissue breaking is accelerated; a dynamic adjusting and filtering mechanism is adopted in the filtering part, filtering modes are switched after stirring, and in-situ separation of the extracting solution and the raw materials is achieved; the elution part drives the cationic resin to be in forced contact with an extracting solution through rotation, and the adsorption efficiency is improved by combining through-channel type resin distribution. The three components cooperatively operate in a single tank, and traditional crushing, extracting, separating and eluting multi-step processes are integrated into a continuous flow. The method has the advantages that the extraction efficiency is improved, the taurine purity is improved, and meanwhile, the material transfer loss and the pollution risk are reduced.

The invention discloses a buoyant raft net cage holothurian culture device and a holothurian culture method. The buoyant raft net cage holothurian culture device comprises a net cage main body, a bait enrichment device and a bait slow release device, the interior of the net cage body is used for containing sea cucumbers. The bait enrichment device is arranged in the net cage main body and comprises at least one deposition structure; the bait slow-release device is arranged in the net cage body and used for controlling the release rate and distribution of bait. According to the novel buoyant raft net cage holothurian culture device and the matched culture method, bait loss can be effectively reduced, the bait utilization rate is increased, and therefore the growth speed and breeding efficiency of holothurian are improved.

The utility model discloses a sea cucumber enzymolysis device, which relates to the technical field of sea cucumber processing, and comprises a tank body, a mixing mechanism is arranged at the top of the tank body, a filtering mechanism is arranged at the bottom of the tank body, the mixing mechanism comprises two electric telescopic rods and a material barrel, the two electric telescopic rods are arranged outside the tank body, and the material barrel is arranged in the tank body. The material barrel is movably installed in the tank body, top blocks are installed at the top ends of the electric telescopic rods, rotating shafts are installed between the inner sides of the two top blocks and the positions, close to the top ends, of the periphery of the material barrel, a motor is installed at the top of the material barrel, and a stirring rod is installed at the position, located in the material barrel, of the bottom end of an output shaft of the motor. A first screw groove is formed in the inner wall, close to the bottom end, of the material barrel; the sea cucumber raw materials can be conveniently added and taken out, the sea cucumber raw materials are separated from the stock solution, the utilization rate of the sea cucumber raw materials is increased, meanwhile, the stock solution can be further filtered, and impurities in the stock solution are reduced.

The invention discloses an easily-occurring sea cucumber processing control method and system based on oxygen injection synergistic hydrotherapy, relates to the technical field of food processing control, and realizes self-adaption and precise control of a sea cucumber processing process through multi-sensor feedback. The method comprises the following steps: firstly, calling a processing technology parameter vector X of a sea cucumber variety to carry out standardization setting, and calculating the maximum oxygen introduction amount OMAX to carry out pretreatment so as to mildly wake up tissues; and then the real-time water turbidity Trt is monitored until the cleaning threshold TMIN is reached, so that deep cleaning is completed. In the secondary hydrotherapy, the real-time oxygen introduction amount Ort is dynamically adjusted to maintain the target dissolved oxygen concentration DO2 of the secondary hydrotherapy, and the processing environment is stabilized. And monitoring the real-time conductivity Crt of the secondary hydrotherapy solution, and ending the conditioning when the change value C of the real-time conductivity of the secondary hydrotherapy solution meets the requirement, thereby realizing the intelligent judgment of the absorption process. And finally, processing is completed after preset standing time tP, and uniform quality is ensured.

The invention discloses sea cucumber peptide, a preparation method, a composition and application, and relates to the technical field of biology. The sea cucumber peptide has the effect of preventing and / or treating alcoholic liver injury and comprises a first polypeptide, a second polypeptide and a third polypeptide, the amino acid sequence of the first polypeptide is ALKTPDK, the amino acid sequence of the second polypeptide is LEREDGPEVTVI, and the amino acid sequence of the third polypeptide is TGVDNPGHP. The sea cucumber peptide is high in activity, good in biocompatibility, safe and free of toxic and side effects, has good activity of preventing and / or treating alcoholic liver injury, and can be used for preparing products for preventing and / or treating alcoholic liver injury.

The invention relates to a preparation method of small-molecular-weight sea cucumber oligopeptide, the prepared sea cucumber oligopeptide and application, and belongs to the technical field of skin care products. The preparation method of the small-molecular-weight sea cucumber oligopeptide comprises the following steps: preparing sea cucumber fine powder; adding the sea cucumber fine powder into ultrapure water, adding papain and EDTA (Ethylene Diamine Tetraacetic Acid), and carrying out enzymolysis under the assistance of microwaves; adding trypsin and calcium ions, and carrying out enzymolysis under the assistance of microwaves; adding neutral protease and zinc ions, and performing enzymolysis under the assistance of microwaves to obtain final sea cucumber enzymatic hydrolysate; and decolorizing, separating and purifying, and freeze-drying to obtain the powdery small-molecular-weight sea cucumber oligopeptide. According to the preparation method of the small-molecular-weight sea cucumber oligopeptide, microwave heating and enzymolysis reaction are combined, the hydrolysis degree of a peptide chain is regulated and controlled by controlling an enzyme hydrolysis sequence and enzymolysis conditions, the small-molecular-weight sea cucumber oligopeptide with relatively concentrated and moderate molecular weight is prepared, and good biological activity of the sea cucumber oligopeptide is kept.

The invention belongs to the technical field of preparation of biological materials, and particularly discloses a sea cucumber flower self-assembled polypeptide-iron nano-carrier as well as a preparation method and application of the sea cucumber flower self-assembled polypeptide-iron nano-carrier. The preparation method comprises the following steps: dissolving freeze-dried sea cucumber flower powder in deionized water, adjusting the pH value to be alkaline, heating and stirring, centrifuging, discarding the precipitate, adjusting the pH value to be acidic, centrifuging, collecting the precipitate, and freeze-drying to obtain sea cucumber flower protein powder; preparing a reaction solution, adding simulated gastric juice and simulated intestinal juice, stirring for reaction, inactivating protease, centrifuging, taking supernatant, and freeze-drying to obtain sea cucumber flower self-assembled polypeptide; the preparation method comprises the following steps: preparing a solution from sea cucumber, adding FeCl2. 4H2O and ascorbic acid, adjusting the pH value to be acidic, carrying out heating reaction, centrifuging, discarding the supernatant, and freeze-drying to obtain the sea cucumber flower self-assembled polypeptide-iron nano-carrier. The invention discloses a sea cucumber flower self-assembled polypeptide-iron nano-carrier as well as a preparation method and application thereof. The carrier can promote absorption of an organism to iron, a relatively high iron ion release rate is maintained in an intestinal environment, and the in-vivo bioavailability of iron ions is improved.

The invention relates to the technical field of preparation methods of giant salamander peptide and eucommia ulmoides male flower tablets, in particular to a preparation method of giant salamander peptide and eucommia ulmoides male flower tablets. The giant salamander peptide and eucommia ulmoides male flower tablets comprise the following raw materials in parts by weight: 30-40 parts of giant salamander peptide powder, 20-25 parts of eucommia ulmoides male flowers, 10-15 parts of rape pollen, 10-15 parts of sea cucumber intestine peptide powder, 10-12 parts of a filler, 3-5 parts of an adhesive and 1-3 parts of a lubricant. According to the invention, the eucommia male flower contains geniposidic acid, chlorogenic acid, aucubin lignin, iridoid and phenylpropanoid natural active nutrient substances, flavonoid compounds, polysaccharide and other bioactive substances in the rape pollen, polysaccharide and peptide components in the sea cucumber intestine peptide powder, and the like. The andrias davidianus peptide powder is added into the andrias davidianus peptide powder, the andrias davidianus peptide powder cooperates with antioxidant peptide and immunomodulatory peptide in the andrias davidianus peptide powder to jointly form a rich bioactive substance library, and the components regulate the physiological functions of the human body from different angles, provide comprehensive nutrition support for the body and improve the fatigue resistance of the human body.

The invention relates to the technical field of medical care, and particularly discloses a preparation method and application of sea cucumber peptide. The preparation method of the sea cucumber peptide provided by the invention comprises the following steps: heating sea cucumber primary pulp for denaturation, and then adding compound protease for enzymolysis treatment to obtain sea cucumber enzymatic hydrolysate; the addition amount of the compound protease is 0.1-0.15 mg / mL, and the compound protease is prepared from papain, ficin and trypsin according to the weight ratio of 1: (0.5-1.5): (2-3); adding activated carbon and diatomite into the sea cucumber enzymatic hydrolysate, and performing enzyme deactivation, filtration and concentration treatment to obtain sea cucumber peptide; the invention also provides application of the sea cucumber peptide obtained by the preparation method in medicines and foods. According to the preparation method of the sea cucumber peptide, the sea cucumber peptide with small molecular weight and good uniformity can be obtained, and the prepared sea cucumber peptide tablet candy has the effects of relieving physical fatigue, resisting aging, resisting oxidation and the like.

The invention belongs to the technical field of food biology, and particularly relates to sea cucumber gonad-derived anti-inflammatory peptide as well as a preparation method and application thereof. The anti-inflammatory peptide is obtained by performing enzymolysis and molecular docking screening on sexual glands of sea cucumbers, and comprises at least one of peptides with amino acid sequences as shown in SEQ.ID.NO.1-3. Experiments prove that the anti-inflammatory peptide has high anti-inflammatory activity, provides a basis for preparing functional food from natural food sources, and has important significance for development of novel anti-inflammatory products.

The invention relates to protein peptide and polysaccharide efficient separation equipment for sea cucumber peptide processing and a use method of the protein peptide and polysaccharide efficient separation equipment, and particularly relates to the technical field of bioengineering. The sea cucumbers are subjected to two-time enzymolysis by adopting two-time enzyme adding and two-time different hydrolase adding in cooperation with different enzymolysis conditions, a first ultrafiltration membrane with the molecular weight cut-off of 10 KDa is selected for first-time ultrafiltration separation, permeate liquid is protein peptide mixed liquid, cut-off liquid is polysaccharide mixed liquid, and the protein peptide mixed liquid and the polysaccharide mixed liquid are mixed. The protein peptide mixed solution and the polysaccharide mixed solution correspondingly enter corresponding ultrafiltration assemblies to be subjected to multi-stage ultrafiltration, protein peptide and polysaccharide are further separated and purified respectively, and finally the protein peptide mixed solution and the polysaccharide mixed solution enter corresponding spray drying towers to be subjected to spray drying to obtain corresponding protein peptide powder and polysaccharide powder; separation, purification and drying of protein peptide and polysaccharide can be achieved at the same time, and waste of resources is reduced.

The invention discloses a sea cucumber flower self-assembled polypeptide-selenium nano-carrier with antioxidant activity and a preparation method and application thereof, belongs to the technical field of functional protein peptides, and particularly relates to a preparation method of the sea cucumber flower self-assembled polypeptide-selenium nano-carrier with antioxidant activity, which comprises the following steps: heating a sea cucumber flower protein solution; the preparation method comprises the following steps: mixing sea cucumber with simulated gastric juice, reacting for 30-150 minutes, then adding simulated intestinal juice, reacting for 20-120 minutes, carrying out enzyme deactivation treatment, centrifuging, taking supernate, and freeze-drying to obtain sea cucumber flower self-assembled polypeptide; and mixing the sea cucumber flower self-assembled polypeptide with deionized water to prepare a sea cucumber flower self-assembled polypeptide solution, mixing the sea cucumber flower self-assembled polypeptide solution with a sodium selenite solution and a phosphate buffer solution, reacting for 20-60 minutes, washing with an ethanol solution, centrifugally collecting precipitate, and freeze-drying to obtain the sea cucumber flower self-assembled polypeptide-selenium nano-carrier. The sea cucumber flower self-assembled polypeptide-selenium nano-carrier prepared by the invention has good antioxidant activity and potential of effectively delivering selenium to an organism.

The invention discloses an active exosome stent coating based on traditional Chinese medicine enhanced secretion promotion and a preparation method and application thereof, and belongs to the technical field of biological medicine and interventional instruments. The stent coating comprises exosomes, wherein the exosomes comprise myocardial cell active exosomes and human mesenchymal stem cell active exosomes which are intensified and secreted by traditional Chinese medicines; wherein the traditional Chinese medicines comprise placenta extract, pilose antler extract, sheep myocardial peptide, sea cucumber peptide, lycium ruthenicum peptide, cnidium lactone, curculigo orchioides extract and morinda officinalis extract; the intervention concentration of each component added into cells is 2-50 [mu] g / mL; the light-cured gel matrix is prepared from methacrylated gelatin, a photoinitiator and polyether 127; tacrolimus; the final concentration of the exosome is 1 * 10 < 9 >-12 * 10 < 9 > particles / mL, and the final concentration of the tacrolimus is 5-25 mu g / mL. The coating can be coated on the surface of the poly-L-lactic acid degradable stent to prepare the degradable stent, and has obvious vascular repair promoting capability.

The invention discloses scallion braised sea cucumber processing and sampling equipment, and relates to the technical field of sampling, the scallion braised sea cucumber processing and sampling equipment comprises a fixed bottom table, the fixed bottom table is provided with a height control mechanism, the height control mechanism is connected with a lifting round block, the lifting round block is provided with a rotary displacement ring mechanism, and the outer side of the rotary displacement ring mechanism is provided with a mounting ring mechanism; the mounting ring mechanism is provided with a plurality of sampling assemblies, each sampling assembly comprises a deflection mounting mechanism, a sampling barrel mechanism and a liquid separation mechanism, the rotary displacement ring mechanism is provided with a driving ring mechanism, and a lifting circular block is fixedly connected with a deflection pressing plate mechanism. And the positions of the sampling assemblies can be adjusted by rotating the displacement ring mechanism, and the sampling assemblies meeting the required number can be mounted through the mounting ring mechanism, so that the material extraction efficiency is improved.

The invention provides a sea cucumber culture fishing underwater robot cooperative work system, and the system comprises a fishing boat module which is used as a water surface control center and provides calculation, communication and power support; the plurality of underwater robot modules are used for executing underwater autonomous navigation, target identification, sea cucumber fishing and data acquisition tasks; the umbilical cable collecting and releasing system module is used for collecting, releasing and managing an umbilical cable for connecting the fishing boat and the underwater robot; a cooperative control system module; a balance adjustment system module; according to the invention, through unified task allocation and dynamic path planning of a plurality of underwater robots, by using an improved A * algorithm and a UWB positioning technology, the plurality of robots can efficiently cover an operation area without omission, and the distance is calculated in real time to trigger an obstacle avoidance program, so that the obstacle avoidance efficiency is improved. The problems of low efficiency, repeated fishing, region omission, high collision risk and the like caused by a traditional manual region division or simple wireless communication cooperation mode are solved.

The invention belongs to the technical field of trepang treatment, and discloses an automatic sectioning and impurity-removing processing device for salted trepang raw materials. The rack main body is used for supporting the conveying device, the pressing device, the expanding and supporting device and the material receiving device; the conveying device is used for continuously and automatically conveying the sea cucumbers and ensuring that the sea cucumbers are conveyed to corresponding positions without damage; the sectioning device is used for sectioning the belly of the sea cucumber to expose the interior of the sea cucumber; the pressing device is used for pressing and fixing the sea cucumber, so that the sectioning device sectioning the abdomen of the sea cucumber; the expanding and supporting device is used for expanding and supporting curled skin of the sectioned sea cucumbers and exposing sand mouths of the heads of the sea cucumbers; the sand nozzle removing device is used for positioning a sand nozzle part of the head of the sea cucumber and completely removing the sand nozzle part; the spraying device is used for cleaning the interiors of abdominal cavities of the sea cucumbers in the processing treatment process and flushing silt and other impurities in the abdominal cavities of the sea cucumbers; and the material collecting device is used for uniformly collecting the processed sea cucumbers, so that subsequent processing operation is facilitated.

The invention belongs to the technical field of medicine, and discloses a sea cucumber and ganoderma lucidum immune steady-state compound and a composite enzymatic hydrolysis targeted liposome co-delivery preparation process thereof.The sea cucumber and ganoderma lucidum immune steady-state compound is composed of sea cucumber, ganoderma lucidum, American ginseng, dried oyster meat, fructus lycii and perilla leaves; the ganoderma triterpenes release free polysaccharides and are combined with a liposome intestinal targeted delivery system, so that the absorption rate of the polysaccharides is greatly improved to 18-22% from 5% in the traditional process, the ganoderma triterpenes are emulsified and entrapped through a liposome double-layer membrane, and meanwhile, the permeation promotion effect of perillaldehyde in the perilla leaf volatile oil is supplemented, so that the transmembrane transport efficiency is remarkably enhanced, the absorption rate is improved to 12-15% from 2%, and the bioavailability is improved. The zinc element decomposes oyster zinc protein into free zinc ions through a composite enzymolysis technology, and the free zinc ions and vitamin C form a stable chelate, so that the antagonism of intestinal tracts is reduced, the zinc absorption rate is increased from 20% to 45-50%, and a solid foundation is laid for fully playing a compound immune regulation effect.

The invention belongs to the technical field of aquaculture feed processing, and particularly relates to a processing technology of a sea cucumber intermediate culture feed. The sea cucumber intermediate breeding feed comprises fish meal, soybean protein isolate, seaweed meal, fermented soybean meal, multivitamins, a multivitamin premix and mineral salt. The processing technology comprises the following steps: firstly carrying out crushing pretreatment on the raw materials, then mixing the crushed raw materials, carrying out hardening and tempering, then carrying out twin-screw extrusion puffing to form carrier particles, carrying out low-temperature drying, then carrying out high-pressure atomization spraying technology to load the fish oil phospholipid complex, carrying out three-stage variable-temperature drying treatment, and finally carrying out cooling screening. The sea cucumber intermediate breeding feed processed by the method can be used for breeding in a transition stage from young sea cucumbers to young sea cucumbers, the survival rate of the young sea cucumbers in the breeding process is increased, and the sea cucumber intermediate breeding feed has the advantages of high nutrient retention rate and slow dissolution loss characteristic; in addition, the invention has the advantage of improving the order of micropores in the particles and the compactness of the surface layer so as to improve the physical stability of the sea cucumber intermediate culture feed.

The invention discloses a holothurian culture feed additive and a preparation method thereof, and belongs to the technical field of aquaculture. According to the technical scheme, the holothurian culture feed additive comprises the following components in percentage by mass: 45%-55% of fish meal, 2%-3% of butyric acid bacteria, 25%-30% of compound probiotics, 2%-4% of a Chinese herbal medicine extract, 8%-12% of a fermentation substrate, 10%-15% of seaweed meal, 0.5%-1% of vitamin E, 0.5%-1% of selenium yeast and the balance of a carrier, the compound probiotics are composed of lactic acid bacteria, bacillus and photosynthetic bacteria according to the mass ratio of 2: 1: 1; the Chinese herbal medicine extract is a mixture of astragalus polysaccharide and an asarum extract in a mass ratio of 3: 1; through the synergistic effect of the fish meal, the compound probiotics, the Chinese herbal medicine extract and other components, nutrition balance and intestinal flora regulation and control are achieved, the problems of slow growth, intestinal diseases and water quality pollution caused by traditional feed are effectively solved, and the sea cucumber feed has the advantages that the survival rate of sea cucumbers is increased, and the culture benefits are increased.

A peptide composition for improving tear stains of pets belongs to the field of pet health, is used for improving tear stains of pets, and is characterized by comprising 20-30 parts of sea cucumber peptide, 5-10 parts of casein phosphopeptides, 10-20 parts of soybean peptide, 20-30 parts of corn oligopeptide, 10-20 parts of wheat oligopeptide and 10-20 parts of mussel peptide, the amino acid sequence of common mussel peptide is His-Gly-Ala-Asp-Gly-Val-Pro-Pro-Phe, and the amino acid sequence of the common mussel peptide is His-Gly-Ala-Asp-Gly-Val-Pro-Pro-Phe. The amino acid sequence of the perna viridis peptide is Asp-Ser-Ser-Leu-Pro-Pro-Ser-Arg-Pro-Thr, and the perna viridis peptide has the effects of effectively improving the metabolism of ferriporphyrin, inhibiting the activity of saccharomycetes and reducing the formation of tear stains of pets.

The invention discloses a sea cucumber polypeptide extraction production line and an extraction process thereof, and relates to the field of sea cucumber polypeptide extraction.The sea cucumber polypeptide extraction production line comprises a smashing tank, a feeding pipe is installed at the top of the outer wall of the smashing tank, a smashing assembly is arranged in the center of the interior of the smashing tank, and a circular ventilation pipe is arranged in the smashing tank and located on the outer side of the smashing assembly; through grooves are symmetrically formed in the wall body of the crushing tank, movable blocks are arranged in the two through grooves, folding plates are fixedly connected to the two side walls of the two movable blocks, fixed blocks are fixed to the groove walls of the two sides of the two through grooves, and the end of each folding plate is fixedly connected with the corresponding fixed block; when sea cucumbers are crushed, air is injected into the sea cucumbers, air lift flow among sea cucumber powder particles is increased, an adsorption layer on the surface is broken, the sea cucumbers are dispersed into the air, adsorption force and attraction force are prevented from being generated among the powder particles, the agglomeration phenomenon is reduced, and the crushing effect is ensured.

The invention discloses a bifunctional active peptide with ACE (angiotensin converting enzyme) and DPP-IV (dipeptidyl peptidase-IV) inhibitory activity as well as a preparation method and application of the bifunctional active peptide, and belongs to the technical field of active peptide biology. The difunctional novel active peptide with ACE and DPP-IV inhibitory activity is prepared and identified from sea cucumber enzymatic hydrolysate, not only can inhibit ACE activity, but also has DPP-IV inhibitory activity, and the difunctional novel active peptide has application value in preparation of products with blood pressure and blood sugar reducing effects. The active peptide provided by the invention can significantly inhibit the activity of ACE, has DPP-IV inhibitory activity, has the characteristics of simple structure, safety, strong activity and the like, can exert nutritional and health-care effects, is expected to provide effective active ingredients for developing food and products having no side effects and having the effects of reducing blood pressure and blood sugar or having the effects of reducing blood pressure and blood sugar and the like, and has a broad application prospect. Wide application prospects are realized.

The invention relates to the technical field of preparation of stimuli-responsive hydrogel, in particular to sea cucumber ion skin imitating double-dynamic topology hydrogel as well as a preparation method and application of the sea cucumber ion skin imitating double-dynamic topology hydrogel. The thermo-sensitive poly (N-isopropylacrylamide) hydrogel is used as a continuous matrix and is used for simulating the dynamic adaptability of sea cucumber skin; and the ionic conductive microgel is used as a rigid dispersion phase and is used for simulating a collagenous fiber network of a connective tissue layer of the sea cucumber. The microgel is dispersed in the poly (N-isopropylacrylamide) hydrogel and is physically entangled with the poly (N-isopropylacrylamide) hydrogel to form a cross-linking point, so that a dynamic network of'rigid node-flexible matrix 'is constructed. The dynamic network structure endows the double-dynamic topological hydrogel with force and heat double toughening properties and ultralow mechanical hysteresis, so that the double-dynamic topological hydrogel has excellent elasticity, fatigue resistance, low hysteresis and strain rate insensitivity, and further shows wide application prospects in the fields of flexible sensing and wearable equipment.

The invention provides a multi-parameter combined control method and system for key nodes in a sea cucumber processing process, and relates to the technical field of automatic control. Executing drying control in a first drying stage according to preset parameters, monitoring to obtain a first sea cucumber image set, extracting a first real-time drying feature, and then calculating a drying feature deviation; and setting a second-stage drying target according to the second-stage drying index and the drying characteristic deviation, performing drying parameter optimization based on the target, determining an optimal second drying parameter to execute second-stage drying control, and performing iterative deviation analysis and drying parameter optimization until a plurality of drying stages are completed. The technical problems that in the prior art, due to the fact that the sea cucumber state cannot be monitored in real time and drying parameters cannot be dynamically adjusted, drying deviation accumulation is caused, and drying uniformity is poor are solved, and the technical effect of improving the overall drying uniformity and quality stability of sea cucumbers is achieved.

The invention relates to the technical field of active peptides, and discloses a whitening and anti-wrinkle protein active peptide composition as well as a preparation method and application thereof. The whitening and anti-wrinkle protein active peptide composition is prepared from the following raw materials in parts by weight: 10 to 15 parts of elastin peptide, 11 to 14 parts of fish collagen peptide, 8 to 10 parts of fish maw small-molecule active peptide, 5 to 10 parts of cubilose peptide, 5 to 10 parts of sea cucumber peptide, 2 to 6 parts of Chinese fevervine herb active peptide, 1 to 3 parts of zingiber corianum active peptide and 1 to 5 parts of lycopene. According to the whitening and anti-wrinkle protein active peptide composition and the preparation method and application thereof, small-molecule active peptide in the prepared protein active peptide composition is beneficial to absorption of dermal cells, and meanwhile, through the synergistic effect of multiple active ingredients, the whitening and anti-wrinkle effects are effectively achieved, the skin quality is improved, and aging is delayed.