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88results about How to "No side effects" patented technology

Traditional Chinese medicine composition with functions of tonifying qi and nourishing blood for livestock and preparation method thereof

InactiveCN103655683AGood for nourishing qi and nourishing bloodGood effect of invigorating qi and nourishing bloodOrganic active ingredientsDigestive systemDiseaseSide effect
The invention relates to a traditional Chinese medicine composition with functions of tonifying qi and nourishing blood for livestock. The traditional Chinese medicine composition comprises the following components in parts by weight: 10-30 parts of astragalus membranaceus, 10-40 parts of spina gleditsiae, 10-20 parts of angelica sinensis, 10-20 parts of codonopsis pilosula, 10-30 parts of uniflower swisscentaury root, 10-30 parts of ligusticum wallichii, 10-20 parts of cowherb seed, 10-20 parts of fruit of liquidambar formosana hance and 1-10 parts of iron sucrose. The traditional Chinese medicine composition is scientific and reasonable in component, free of toxic and side effects and medicine residue, convenient to take and low in cost, has the functions of tonifying qi and nourishing blood, stimulating the menstrual flow and prompting lactation, and is capable of effectively treating diseases of postpartum hypogalactia, breast milk stoppage and the like which are normal in livestock.
Owner:TIANJIN REBATE SCI & TECH DEV

A traditional Chinese medicine composition and health-care beverage with the effects of inducing perspiration and promoting saliva production

PendingCN122251543ACompatibilityThe party is rigorousOrganic active ingredientsMetabolism disorderCeltis bungeanaWolfiporia extensa
The present application relates to the technical field of traditional Chinese medicine compositions, and specifically discloses a traditional Chinese medicine composition with the effects of stopping sweating and promoting fluid production and a health-care beverage. The composition is prepared from raw licorice, schisandra chinensis, radix codonopsis, momordica grosvenori, coix seed, poria cocos, edible salt, glucose, mint, raw ginger, honeysuckle, bamboo leaf, radix trichosanthis, celtis bungeana, white cardamom in a specific weight ratio. The composition uses schisandra chinensis as the monarch herb to stop sweating and promote fluid production, radix codonopsis and raw licorice to supplement qi and consolidate the exterior, radix trichosanthis, bamboo leaf and celtis bungeana to clear heat and promote fluid production, coix seed, poria cocos and white cardamom to invigorate the spleen and eliminate dampness, honeysuckle and mint to clear away summerheat, raw ginger to warm the center and prevent cold, and momordica grosvenori to harmonize the taste and supplement electrolytes and energy. The composition can be used to prepare an oral health-care beverage, has the effects of stopping sweating and promoting fluid production, supplementing qi and consolidating the exterior, and supplementing electrolytes, is suitable for scenes of excessive sweating, thirst and fatigue, has a good taste, is safe, and is simple to prepare.
Owner:梁敬

Preparation method and application of vanadium oxide anode and cathode materials in zinc ion battery

The invention discloses a process for preparing a V2O3 / ZnV2O3 total battery by simultaneously using vanadium oxide in a zinc ion battery as a positive electrode material and a negative electrode material, which comprises the following steps: reacting ammonium metavanadate with absolute ethyl alcohol by adopting a solvothermal synthesis method, washing, drying, and calcining in a tubular furnace to obtain V2O3; in the preparation process of the V2O3 positive electrode material, only V2O3, acetylene black serving as a conductive agent and PVDF serving as a binder are mixed in proportion and then are coated on graphite paper, other coating protection materials do not need to be introduced into a V2O3 / Zn negative electrode, and V2O3 is used as a protection layer to inhibit growth of zinc dendrites, relieve hydrogen evolution side reaction of the zinc negative electrode and reduce corrosion of zinc. Vanadium oxide V2O3 is directly used as a core positive electrode material, the zinc negative electrode coating is developed by utilizing the characteristics of the vanadium oxide V2O3, a material is formed, meanwhile, the performance optimization of the positive electrode and the negative electrode is realized, the used raw materials are simple and easy to obtain, the process is simple and easy to implement, and the preparation process is simple and easy to implement from V2O3 raw material synthesis to positive and negative electrode piece preparation to V2O3 / ZnV2O3 total battery assembly. And comprehensive improvement of positive and negative electrode performances of zinc ions is simultaneously realized by a single material.
Owner:ANHUI AGRICULTURAL UNIVERSITY

Cosmetic product for sensitive skin and method for preparing the same

ActiveCN117180148Bless irritatingRepair skin barrier function
The application discloses a kind of cosmetics suitable for sensitive skin and preparation method thereof, preparation raw materials include A phase, B phase, C phase and D phase;The preparation raw materials of A phase include emulsifier, emollient, thickening agent, antioxidant;The preparation raw materials of B phase include water, humectant, chelating agent, thickening agent B;The preparation raw materials of C phase include emulsifier C, humectant C, plant extract;The preparation raw materials of the D phase include preservative.The application does not contain synthetic pigment, plastic micro powder, mineral oil and other harmful ingredients of skin, nature is mild, no stimulation, no toxic side effect, the subject is continuously used the cosmetic prepared by the application 28 days, and the decrease rate of lactic acid stinging score compared with base value is 50.38%, and product effect is remarkable, and effect is fast.
Owner:LKF GUANGDONG MEDICAL

Mussel mucin-chondroitin sulfate composite hydrogel as well as preparation method and application thereof

The invention relates to the technical field of medical biological materials, and discloses a mussel mucin-chondroitin sulfate composite hydrogel and a preparation method and application thereof, and the preparation method comprises the following steps: respectively preparing a mussel mucin aqueous solution and a chondroitin sulfate aqueous solution; the mass volume concentration of the mussel mucoprotein aqueous solution is 1%-10%, the mass volume concentration of the chondroitin sulfate aqueous solution is 1%-10%, the mass ratio of the mussel mucoprotein to the chondroitin sulfate is 3: 1-1: 3, the two solutions are mixed and stirred or oscillated under the conditions that the temperature is 4-37 DEG C and the pH value is 7.0-9.0, a cross-linking reaction is conducted, and hydrogel is formed; the cross-linking mode is physical cross-linking, chemical cross-linking or physical-chemical dual cross-linking; according to the invention, excellent tissue adhesion, injectability, self-healing property and biodegradability are realized, cell adhesion and proliferation can be effectively promoted, and the gel is suitable for various medical beauty scenes such as skin filling, wound repairing and anti-aging nursing.
Owner:RUIFUXIN (SUZHOU) MEDICAL TECHNOLOGY CO LTD

A traditional Chinese medicine extract for anti-inflammatory and scar-reducing purposes, its preparation method, and its application.

This invention discloses a traditional Chinese medicine extract for anti-inflammatory and scar-reducing purposes, its preparation method, and its application. The extract is obtained by mixing broken-cell wall Ganoderma lucidum spore powder and sea buckthorn seed powder in a weight ratio of 5-8:2-5, followed by dry granulation and supercritical CO2 extraction. This invention's traditional Chinese medicine extract for anti-inflammatory and scar-reducing purposes is prepared by mixing and granulating broken-cell wall Ganoderma lucidum spore powder and sea buckthorn seed oil, followed by supercritical CO2 extraction. The process is simple, energy-efficient, environmentally friendly, stable, and has high extraction efficiency. It exhibits significant anti-inflammatory and scar-reducing functions and has no toxic side effects.
Owner:ZHONGKE HEALTH IND GRP JIANGSU PHARM CO LTD

Cultivation method for cultivating XX pseudo male fishes by using Chrysophila multistriata

The invention belongs to the technical field of breeding of aquatic animals, and particularly relates to a breeding method for breeding XX pseudo male fishes by using Chrysophila multistriata. The invention relates to a breeding method for breeding XX pseudo-male fishes by using Christia polyrrhiza, which comprises the following steps of: feeding a feed containing an aromatase inhibitor to Christia polyrrhiza fry with proper day age for induction to obtain pseudo-male fishes with physiological male property and genetic female property; the method comprises the following steps: performing PIT living body electronic marking, then collecting a tail fin tissue sample, performing PCR detection by utilizing a genetic sex specific molecular marker of the Chrysophila polyrrhiza, and screening out pseudo male individuals with female genetic sex and male physiological sex; the obtained pseudo male fish individuals serve as male parents, normal genetic female fishes serve as female parents, intensive cultivation and artificial spawning induction are conducted, and fertilized eggs are obtained; the obtained fertilized eggs are collected and hatched, and pseudo male fishes with all genotypes being XX are obtained. According to the method, the genetic all-female rate of the breeding offspring reaches 100%, and the production purity of the offspring seeds is greatly improved.
Owner:GUANGDONG OCEAN UNIVERSITY +1

Power supply capability judging device, electronic device, and power supply capability judging method

ActiveCN116413525Bno side effectsPower capability implementation
The present application provides a power supply capability judging device for judging a power supply capability of a power supply, comprising a connector, a load circuit, a switch circuit, a voltage monitoring circuit and a processing circuit. The connector is used for receiving the power supply to output an input voltage at a power supply output end. The switch circuit is electrically connected between the load circuit and the power supply output end. The voltage monitoring circuit is electrically connected to the power supply output end and used for monitoring the input voltage to generate a monitoring voltage value. The processing circuit is electrically connected to the voltage monitoring circuit and the switch circuit and used for controlling the switch circuit. Under the control of the processing circuit, the monitoring voltage value is received and the power supply capability of the power supply is judged according to the monitoring voltage value.
Owner:REALTEK SEMICON CORP

A type of acupoint warming patch composed of five kinds of traditional Chinese medicine

This invention discloses an acupoint warming patch composed of five kinds of traditional Chinese medicine, belonging to the technical field of external health care patches. The patch contains a medicinal pack made of mugwort leaves, ginger, scallion, cinnamon twig, and angelica root, with a weight ratio of 1:1:1:1:1. The mugwort leaves are from the Dragon Boat Festival, the ginger is peeled, the scallion is from seasonal scallions, and the cinnamon twig is a tender branch of a cassia branch. These five herbs are both medicinal and edible, and are used for treating colds caused by wind and cold. This acupoint warming patch provides heat therapy, warming and unblocking the meridians, dispelling cold and relieving exterior symptoms, and warming and supporting the body's defensive energy. It is applied to the Dazhui acupoint to prevent colds caused by wind and cold, is gentle on the outside, and has no side effects.
Owner:汪如亮

A pharmaceutical composition for treating infant night cough, preparation and application thereof

ActiveCN117919351BSignificant effectto achieve conditioningRespiratory disorderPlant ingredientsAdjuvantNocturnal cough
The application discloses a medicine composition for treating infant night cough, which is composed of Radix Bupleuri, Radix Paeoniae Alba, Fructus Aurantii Immaturus, roasted Germinated Millet, roasted Millet, Pericarpium Citri Reticulatae, Folium Pyrrosiae, Radix Trichosanthis, Radix Pulsatillae, Radix Anemarrhenae, Radix Peucedani, Radix Trichosanthis, Radix Ophiopogonis, Radix Sophorae Immaturus, and Radix Glycyrrhizae. The medicine composition can be added with pharmaceutically acceptable adjuvants to form preparations. The medicine composition and the preparations can be used for preparing medicines for treating infant night cough.
Owner:LUXI COUNTY TRADITIONAL CHINESE MEDICINE HOSPITAL

A traditional Chinese medicine composition for tonifying qi and nourishing blood and a preparation method thereof

PendingCN122499273AFormulation ScienceFull effect
This invention discloses a traditional Chinese medicine composition for replenishing qi and nourishing blood, and its preparation method, belonging to the technical field of food-medicine homology traditional Chinese medicine health care preparations. The composition of this invention uses oyster peptide powder, compound amino acid powder, polygonatum powder, maca powder, eucommia male flower powder, ginseng powder, cordyceps powder, and earthworm protein peptide powder as core active ingredients, supplemented with deer antler powder, deer tendon powder, and deer blood peptide powder to enhance the effects of strengthening the body and nourishing blood. It is combined with xylitol, corn starch, maltodextrin, magnesium stearate, and caramel color as molding excipients. The dosage of each component is precisely controlled. Through a proprietary preparation process involving raw material pretreatment, segmented gradient mixing, and refined post-processing, a 1g / tablet formulation is prepared. The formulation of this invention is rigorously formulated, with clear distinctions between principal, assistant, and adjuvant ingredients, and each component synergistically enhances its effect. It can fundamentally improve problems such as qi and blood deficiency, insufficient vital energy, fatigue, and physical weakness. It has comprehensive efficacy, rapid onset of action, and wide applicability, possessing extremely high industrial promotion and health care application value.
Owner:WENZHOU XINMU BIOTECHNOLOGY CO LTD

Procyanidine B2G2 derived from purple sweet potato Ningzi No.4 and application of procyanidine B2G2

PendingCN121949264AImprove pathological damagereduce peroxidationOrganic active ingredientsOrganic chemistryInflammatory factorsLiver and kidney
The invention discloses procyanidine B2G2 from purple sweet potato Ningzi No.4 and application thereof, and belongs to the technical field of biological medicine, the molecular formula of the procyanidine B2G2 is C44H34O20, and the molecular weight of the procyanidine B2G2 is 882.736 Da. The procyanidine B2G2 remarkably relieves acute lung injury ALI by inhibiting inflammatory response and ferroptosis induced by klebsiella pneumoniae KP; experiments show that B2G2 can reduce the lung tissue injury score, the lung wet / dry ratio, the expression of inflammatory factors TNF-alpha, IL-6 and IL-1beta and the bacterial load, and up-regulate the expression of ferroptosis related proteins GPX4, SLC7A11 and HO-1; in addition, B2G2 is non-toxic to liver and kidney functions and has good safety, and the application provides a new drug candidate scheme for preparation of drugs for treating acute lung injury.
Owner:NANTONG UNIV

Efficient mosquito repellent liquid and preparation method thereof

PendingCN121796282AExtend effective repellent timeEffective repelling time increasedBiocideCosmetic preparationsOrganic chemistryToxicology
According to the efficient mosquito repellent liquid and the preparation method thereof, trans-menthanediol serves as a main active component, cis-menthanediol can serve as a secondary active component, the total content of trans-menthanediol and cis-menthanediol is 6%-20%, and the effective repelling time of the mosquito repellent liquid is remarkably prolonged; in addition, by increasing the proportion of the trans-menthanediol with the configuration, the effective mosquito-repelling time of the mosquito-repelling liquid is remarkably prolonged under the same concentration; on the basis, a small amount of eucalyptus citriodora essential oil is added to serve as a synergistic component, synergistic interaction can be further achieved, the continuous mosquito repelling performance is improved, and the whole formula is free of toxic and side effects and high in safety.
Owner:JIANGSU NINGLU TECH CO LTD

Animal bifidobacterium lactis strain hnu329 with uric acid reducing ability and application thereof

ActiveCN119639624BImprove surface hydrophobicityExcellent self-cohesionBacteriaAntipyreticBiotechnologyPurine
The application provides an animal Bifidobacterium lactis HNU329 with the ability of reducing uric acid and an application thereof, the animal Bifidobacterium lactis HNU329 has been preserved in the Guangdong Microbial Culture Collection Center (GDMCC), the preservation address is the 5th floor of the 59th building of the courtyard, No. 100, Jiefang Road, Guangzhou, the preservation date is April 22, 2024, the preservation number is GDMCC No: 64546, and the classification and naming are Bifidobacterium animalis subsp. Lactis. The strain has good degradation abilities of nucleosides and purines in vitro, also shows good uric acid reducing ability and anti-inflammatory ability in animal model evaluation, and can regulate the intestinal flora of hyperuricemia mice and improve the symptoms of hyperuricemia. The strain is non-toxic and has no side effects, is safe, and has a wide application prospect.
Owner:HAINAN UNIV

Preparation method of traditional Chinese medicine combination for treating nephroptosis, pyelonephritis ascites and nephritis

PendingCN122321071Aeasy to useHigh cure rateNephroptosisRegimen
This invention provides a traditional Chinese medicine composition for treating renal edema, pyelonephritis with ascites, and nephritis. It consists of over 20 herbs including Atractylodes lancea, Areca catechu, Saposhnikovia divaricata, and Alisma plantago-aquatica (specific formulation details can be found in the original text). It can be prepared as pills, granules, or decoctions for oral administration. Core efficacy: 1. Promotes diuresis and reduces swelling, eliminating renal ascites; 2. Clears heat and detoxifies, anti-inflammatory and antibacterial (synergistic effect on fungal infections and cervical erosion); 3. Regulates renal function and improves abnormal uric acid metabolism. Treatment plan: Mild cases: Use five basic formulas (①-⑤) composed of Codonopsis pilosula, Poria cocos, etc., taken three times daily; Severe cases: Use a potent diuretic formula containing Akebia trifoliata and Euphorbia pekinensis (one spoonful of pills twice daily); Treatment course is approximately one month, with a follow-up examination after three months. Advantages: Cure rate reaches 90%, low recurrence rate – pure traditional Chinese medicine preparation, no significant toxic side effects; also treats complications (fungal infection, cervical lesions). This treatment plan has been clinically verified through three generations and has significant efficacy in treating renal edema, ascites, and nephritis.
Owner:李爱松

Effervescent tablet for regulating blood sugar as well as preparation method and application of effervescent tablet

The invention relates to the technical field of health-care beverages, and particularly provides effervescent tablets for regulating blood sugar as well as a preparation method and application of the effervescent tablets. The effervescent tablet comprises the following raw materials in parts by weight: 20-30 parts of grifola frondosa polysaccharide, 10-25 parts of ganoderma lucidum polysaccharide, 5-15 parts of phellinus igniarius polysaccharide, 8-12 parts of citric acid, 15-30 parts of sodium bicarbonate, 10-15 parts of a filling agent, 3-5 parts of an adhesive, 0.5-2 parts of a sweetening agent and 1-3 parts of a lubricating agent, adopts a direct tabletting technology, and comprises the steps of material mixing, drying, uniform mixing and tabletting. The process is simplified, manpower, time, water and electricity are saved, the production cost is greatly reduced, and the blood sugar reducing effect is obvious through the steps of adjusting the reasonable amount of the acid agent and the reasonable amount of the alkali agent and finishing the granules.
Owner:MICROBIOLOGY INST OF SHAANXI

A shrimp head hydrolysate with anti-freezing activity, and a preparation method and application thereof

ActiveCN120818579BImprove frost resistanceHigh antifreeze activityMicroorganism based processesPeptide preparation methodsShrimpHydrolysate
The application discloses a shrimp head hydrolysate with anti-freezing activity and a preparation method and application thereof, and belongs to the technical field of biology. The shrimp head is treated by fermentation with the aid of a magnetic field and Pediococcus pentosaceus, and a shrimp head hydrolysate with high anti-freezing effect is prepared. Six polypeptides with high anti-freezing activity are identified from the shrimp head hydrolysate through mass spectrometry analysis. The polypeptides have high ice recrystallization inhibition activity, can inhibit the formation of ice crystals and the migration of water during the food freezing process, reduce the mechanical damage of ice crystals to food, inhibit the protein denaturation caused by ice crystals, and can also reduce the thawing loss and cooking loss of food, and has great application value in food frozen storage.
Owner:GUANGDONG OCEAN UNIVERSITY

Application of ginseng leaf polysaccharide in relieving fish quality decline caused by hypoxia in water body

The invention discloses application of ginseng leaf polysaccharide in relieving fish quality decline caused by water hypoxia, and belongs to the technical field of aquatic product culture. The ginseng leaf polysaccharide is applied to relieving fish quality decline caused by water hypoxia for the first time, and by adding the ginseng leaf polysaccharide, the problems of fish muscle oxidative damage, poor texture property, low nutritional value and the like caused by hypoxia stress can be effectively improved; the invention provides a new relieving technology for improving fish quality decline caused by hypoxia in culture, provides technical support for improving fish quality of cultured fishes under intensive culture conditions, improves freshwater fish culture benefits, and solves the problem of lack of a safe and reliable method for relieving fish quality decline caused by hypoxia in a water body at present.
Owner:SICHUAN AGRI UNIV +1

An antibacterial hydrogel made from traditional Chinese medicine for ulcer healing, its preparation method and application

PendingCN122075610AImprove pathological structureNo side effectsAntibacterial agentsAerosol deliveryPolyvinyl alcoholScrophularia
This invention belongs to the field of traditional Chinese medicine technology, specifically relating to a herbal antibacterial hydrogel for ulcer healing, its preparation method, and its application. The hydrogel is composed of a herbal composition and a matrix. The herbal composition includes dandelion, angelica, scrophularia, forsythia, phellodendron, atractylodes, angelica dahurica, and raw licorice. The matrix contains chitosan, polyvinyl alcohol, water, and glacial acetic acid. The effective components of the herbal medicine are extracted by decoction, concentrated, and freeze-dried to obtain a freeze-dried powder. This powder is then mixed with a chitosan aqueous solution and cross-linked using a liquid nitrogen cyclic freezing method to form the hydrogel. This invention closely addresses the core pathogenesis of diabetic foot ulcers—"blood stasis, dampness, and heat (toxin)"—allowing the various herbs to synergistically exert their effects of clearing heat and detoxifying, promoting blood circulation and removing blood stasis, drying dampness and astringing sores, and nourishing blood and promoting tissue regeneration. The chitosan matrix endows the hydrogel with good biocompatibility, antibacterial properties, and sustained-release drug properties, which can improve the microenvironment of the ulcer wound, inhibit inflammatory responses, and promote granulation tissue growth, effectively promoting the healing of skin sores such as diabetic foot ulcers, and has broad application prospects.
Owner:SHANDONG UNIV OF TRADITIONAL CHINESE MEDICINE

Traditional Chinese medicine composition and traditional Chinese medicine liniment for treating primary dysmenorrhea

The application discloses a traditional Chinese medicine composition and a traditional Chinese medicine ointment for treating primary dysmenorrhea, and relates to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition for treating primary dysmenorrhea comprises the following raw materials in parts by weight: 25-35 parts of angelica sinensis, 25-35 parts of semen stercorei, 15-25 parts of corydalis, 15-25 parts of cumin, 15-25 parts of five musk, 10-20 parts of ginger, 10-20 parts of cassia bark, 5-10 parts of asarum, 5-10 parts of ramulus cinnamomi and 5-10 parts of curcuma zedoary. The application has the advantages of reasonable compatibility, rich raw materials, effective combination between components, convenient use, good effect, innovation in treating primary dysmenorrhea, good popularization and application value and practical clinical significance.
Owner:HENAN UNIV OF CHINESE MEDICINE

Application of fructus cannabis protein hydrolysate in prevention and treatment of ulcerative colitis

The invention relates to a fructus cannabis protein hydrolysate and application thereof in preventing and treating ulcerative colitis and intestinal barrier dysfunction.
Owner:TSINGHUA SHENZHEN INTERNATIONAL GRADUATE SCHOOL

Lactococcus garviae LG3092 producing bacteriocin GarQ and efficiently antagonizing multi-drug resistant helicobacter pylori and application thereof

ActiveCN117660238BNo side effectsNo residual riskBinding siteHigh survival rate
This invention discloses a strain of *Lactococcus gasseri* LG3092 that produces the bacteriocin GarQ and effectively antagonizes multidrug-resistant *Helicobacter pylori*, and its applications. *Lactococcus gasseri* LG3092 was deposited at the Guangdong Provincial Microbial Culture Collection Center on October 30, 2023, with accession number GDMCC No: 63939. Studies have shown that LG3092 has the following beneficial effects: (1) it can produce the bacteriocin GarQ, effectively inhibiting the growth of *Helicobacter pylori* and other common pathogenic bacteria; (2) it has a high survival rate in the stomach, can colonize the stomach, and can compete with pathogenic bacteria for binding sites, effectively reducing the infection rate of *Helicobacter pylori* in the stomach; (3) it can improve the pathological state of the stomach and alleviate inflammation. Therefore, *Lactococcus gasseri* LG3092 has great application potential in the preparation of products for the prevention or treatment of *H. pylori*, especially multidrug-resistant *H. pylori* infection.
Owner:GUANGDONG INST OF MICROBIOLOGY GUANGDONG DETECTION CENT OF MICROBIOLOGY +1

A degradable packaging film containing mulberry leaf extract and a preparation method thereof

This invention relates to the field of biodegradable packaging film technology, and in particular to a biodegradable packaging film containing mulberry leaf extract and its preparation method. The film is prepared from the following raw materials in parts by weight: 40-60 parts chitosan, 20-30 parts sodium alginate, 10-20 parts gelatin, 1-3 parts nano zinc oxide, 3-8 parts mulberry leaf extract, 0.5-1.5 parts crosslinking agent, 3-6 parts plasticizer, 0.1-0.5 parts nano titanium dioxide, and 0.5-1 parts cellulose nanocrystals. This invention uses chitosan, sodium alginate, and gelatin as biodegradable matrices, and combines them with mulberry leaf extract, nano zinc oxide, nano titanium dioxide, and cellulose nanocrystals. These are crosslinked with a food-grade crosslinking agent to form a dense three-dimensional network. The resulting packaging film possesses biodegradability, high strength and high barrier properties, water resistance, broad-spectrum antibacterial properties, strong antioxidant properties, and highly efficient photocatalytic ethylene removal capabilities. The entire preparation process is green, leaves no organic solvent residue, and is simple to operate.
Owner:CHENGDE ACAD OF AGRI & FORESTRY

Near-infrared fluorescent silicon dots, preparation method thereof and application thereof in antibacterial and tumor treatment

ActiveCN118109189BHigh fluorescence intensityHigh quantum yieldPowder deliveryPhotodynamic therapyFluoProbesPhoto stability
This invention discloses a near-infrared fluorescent silicon dot, its preparation method, and its application in antibacterial and tumor treatment. The silicon dot is generated via a one-step hydrothermal method through a high-temperature condensation reaction between the carboxyl group of a 4-carboxyporphyrin dye and the amino group of a silane coupling agent. The silicon dot synthesized in this invention exhibits excellent water dispersibility, high near-infrared fluorescence intensity and pH stability, uniform morphology, good photostability, good biocompatibility, and high reactive oxygen species (ROS) yield. Furthermore, the preparation method is simple and convenient, uses widely available raw materials, and is low-cost, making it suitable for industrial production. Based on these excellent properties, it can be used to prepare fluorescent probes as fluorescent markers for cell and biological imaging. Its excellent singlet oxygen generation performance can be used for photodynamic therapy against bacteria and tumors. In addition, the silicon dot also possesses peroxidase properties, catalyzing the generation of hydroxyl radicals from hydrogen peroxide, thus enabling its use in chemokinetic therapy.
Owner:JIANGSU UNIV OF SCI & TECH

Pet nutrition composition based on gut-brain axis regulation and application thereof

The application discloses a pet nutrition composition based on intestinal-brain axis regulation and application thereof, and the composition comprises 5-20% of probiotics, 10-25% of prebiotics, 2-10% of neurotransmitter precursors, 5-15% of anti-inflammatory and neurotrophic factors, 1-10% of plant extracts and the rest of carriers. The application remolds intestinal microecology by the synergy of probiotics and prebiotics, promotes the synthesis of 5-hydroxytryptamine and dopamine by neurotransmitter precursors, exerts the neuroprotective and anti-inflammatory effects by omega-3 fatty acids, vitamin B group and magnesium elements, realizes the anti-anxiety and tranquilizing effects by L-theanine, chamomile and lavender extracts, and forms a regulation link of multi-target point synergistic intervention of intestinal-brain axis. According to animal experiment verification, the application can significantly improve the anxiety behavior of pets, improve the content of fecal short-chain fatty acids, remodel the intestinal flora structure, and realize the synergistic effect of 'intestinal health-nerve regulation-behavior improvement'.
Owner:KAOLA BIOTECHNOLOGY (SHANDONG) CO LTD

Traditional Chinese medicine composition suitable for type II diabetes as well as preparation method and application of traditional Chinese medicine composition

PendingCN121987730AExact curative effectExact medicationMetabolism disorderEndocrine system disorderCorn silkOphiopogon japonicus
The invention relates to the technical field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition suitable for type II diabetes and a preparation method and application thereof. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 30 to 45 parts of radix astragali seu hedysari, 20 to 30 parts of herba dendrobii, 30 to 45 parts of rhizoma polygonati, 20 to 30 parts of radix ophiopogonis and 20 to 30 parts of corn stigma. According to the traditional Chinese medicine composition, through the synergistic effect of core components such as astragalus membranaceus for tonifying qi, lifting yang, promoting salivation and nourishing blood, dendrobium nobile for tonifying stomach and promoting salivation, polygonatum kingianum for tonifying qi, nourishing yin, moistening lung and tonifying kidney, radix ophiopogonis for nourishing yin and promoting salivation and the like, glucose metabolism balance is effectively adjusted, insulin resistance is improved, and therefore the effect of reducing blood glucose and / or lipid is achieved.
Owner:GUANGMING HOSPITAL OF TRADITIONAL CHINESE MEDICINE PUDONG NEW AREA SHANGHAI

MiR-23a-5p cavernous body, cavernous adeno-associated virus, preparation method of miR-23a-5p cavernous body and cavernous adeno-associated virus and application of miR-23a-5p cavernous adeno-associated virus

PendingCN121801901AAlleviate impairment of secretory functionreduce resistanceMetabolism disorderMicroorganism based processesAdenoassociated virusNucleotide
The invention relates to the technical field of biological medicines, in particular to a miR-23a-5p cavernous body, a cavernous adeno-associated virus, a preparation method of the miR-23a-5p cavernous body and the cavernous adeno-associated virus and application of the miR-23a-5p cavernous body and the cavernous The invention provides a miR-23a-5p cavernous body, and the nucleotide sequence of the miR-23a-5p cavernous body is as shown in SEQ ID NO. 1. The miR-23a-5p cavernous body and the miR-23a-5p cavernous adeno-associated virus prepared from the miR-23a-5p cavernous body can effectively relieve insulin secretion function damage caused by islet glucose stimulation and peripheral tissue insulin resistance caused by high-fat feeding, and can be used as a miR-23a-5p inhibitor to inhibit miR-23a-5p expression in adipose tissues, improve insulin resistance and inhibit the growth of the adipose tissues. And occurrence and development of type 2 diabetes mellitus are controlled.
Owner:NANJING MEDICAL UNIV

A pharmaceutical composition for treating rheumatic arthralgia, its formulation and application

PendingCN122075592AEnhance immune functionanti-inflammatoryAntipyreticAnalgesicsSalvia miltiorrhizaAngelica Sinensis Root
This invention discloses a pharmaceutical composition, its formulation, and its application for treating rheumatic arthralgia. The pharmaceutical composition comprises the following components in parts by weight: 20-40 parts of Salvia miltiorrhiza, 10-20 parts of Paeonia lactiflora, 20-40 parts of Panax notoginseng rootlets, 10-20 parts of Ligusticum chuanxiong, 9-20 parts of Angelica sinensis, 9-20 parts of Clematis chinensis, 9-20 parts of Angelica pubescens, 9-20 parts of Chaenomeles speciosa, 9-20 parts of Saposhnikovia divaricata, 9-20 parts of Achyranthes bidentata (processed with wine), and 9-20 parts of Carthamus tinctorius. Pharmaceutically acceptable excipients may be added to the pharmaceutical composition to prepare a formulation. The pharmaceutical composition and its formulation can be used to treat rheumatic arthralgia.
Owner:HUALONG SHENGAI TRADITIONAL CHINESE MEDICINE GRP CO LTD +1

Pharmaceutical composition for delaying aging and capable of antioxidation

PendingCN122681946ASufficient sourceNo side effects
The application discloses a medicine composition for delaying aging and resisting oxidation, and belongs to the technical field of biological medicine and health food. The composition comprises vitamin A, beta-carotene, compound vitamin B, vitamin C, vitamin D, vitamin E, vitamin K, and macroelements calcium, phosphorus, potassium, magnesium and trace elements zinc, selenium, iron, chromium, copper, molybdenum, iodine, fluorine and manganese, traditional Chinese medicines ginseng, astragalus root, medlar, prepared rehmannia root, ganoderma lucidum, conditional essential nutrients nucleic acid, and bioactive ingredients grape seed extract, lycopene, tea polyphenol, taurine, lutein, lutein fat, corn xanthophyll and chlorophyll; the composition is mainly suitable for middle-aged and old people; the composition can eliminate various factors causing aging from multiple systems, multiple links and multiple targets, can significantly delay aging, has the health care and tonifying effects of resisting oxidation and the like, can improve the life quality of the middle-aged and old people while delaying aging, and has no compatibility contraindication and will not produce any toxic and side effects after long-term use.
Owner:BEIJING GUANWUZHOU BIOSCIENCE INSTITUTION (CN)