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549 results about "Palmitic acid" patented technology

Palmitic acid, or hexadecanoic acid in IUPAC nomenclature, is the most common saturated fatty acid found in animals, plants and microorganisms. Its chemical formula is CH₃(CH₂)₁₄COOH, and its C:D is 16:0. As its name indicates, it is a major component of the oil from the fruit of oil palms (palm oil). Palmitic acid can also be found in meats, cheeses, butter, and other dairy products. Palmitates are the salts and esters of palmitic acid. The palmitate anion is the observed form of palmitic acid at physiologic pH (7.4).

Synergistic compositions for improving mineral bioaccessibility

A synergistic composition for improving the bioaccessibility of minerals comprises lutein, a casein phosphopeptide, or a 1, 3-dioleoyl-2-palmitic acid triglyceride, preferably in combination with one or more non-digestible oligosaccharides. These compositions are useful for the prevention and / or treatment of mineral deficiency and related conditions, preferably anemia, said minerals comprising iron and / or calcium.
Owner:NV NUTRICIA +1

Low-migration UV inkjet ink and preparation method thereof

The invention discloses low-migration UV ink-jet ink and a preparation method thereof, and belongs to the technical field of novel ink. Comprising the following components in parts by mass: 10-15 parts of a dynamic cross-linked polyurethane acrylate oligomer, 5-8 parts of an epoxy silicone resin oligomer, 2-3 parts of modified silicon dioxide, 4-5 parts of a photoinitiator, 15-20 parts of sorbic acid modified color paste, 1-2 parts of nano cerium oxide and 0.5-1 part of an antioxidant. The molecular chain of the dynamic cross-linked polyurethane acrylate oligomer prepared by the invention contains an active group capable of forming a cross-linked structure and a dynamic covalent bond. The groups and bonds promote molecular chain crosslinking when the ink is cured, a three-dimensional network is formed, and the molecular crosslinking density is improved. Through interaction of palmitic acid modified silicon dioxide and oligomer, the palmitic acid modified silicon dioxide is uniformly dispersed in a matrix and interferes molecular chain movement during curing, so that the crosslinking density is further improved, an ink film layer is more compact and firmer, the wear resistance and the scratch resistance are improved, and the tinting strength and the stability are indirectly enhanced.
Owner:深圳永昌和科技有限公司

Tree shrew hypertension model making method

The invention discloses a tree shrew hypertension model making method. The method comprises the following steps: (1) solvent preparation: dissolving palmitic acid in absolute ethyl alcohol to prepare 24mg / ml storage liquid for later use; and (2) diluting the stock solution in the step (1) with 10% BSA (Bovine Serum Albumin) into a solution with the concentration of 6mg / ml, and injecting the solution into the abdominal cavity of the tree shrew according to the dosage of 20mg / kg for 21d to finish modeling. The model preparation method is simple, and the model forming rate is high.
Owner:LABREAL BIOTECH KUNMING CO LTD +1

Pseudomonas monteilii BDLZ-3 and application thereof in relieving continuous cropping obstacles of crops

The invention belongs to the technical field of microorganisms, and particularly relates to pseudomonas monteilii BDLZ-3 and application thereof in relieving continuous cropping obstacles of crops. The invention discloses a strain of pseudomonas monteilii BDLZ-3, the preservation number of which is CGMCC (China General Microbiological Culture Collection Center) No.34349. The pseudomonas monteilii BDLZ-3 is separated and screened from the nature for the first time, phenolic acid autotoxic substances generated in the ginseng continuous cropping obstacle process can be efficiently degraded, the degradation rate of benzoic acid can reach 95.36%, various phenolic acids such as vanillic acid, cinnamic acid, palmitic acid and gallic acid can be effectively degraded, and the degradation spectrum is wide; when the pseudomonas monteilii BDLZ-3 is applied in a field, the content of benzoic acid in soil can be effectively reduced, meanwhile, the occurrence of ginseng root diseases can be controlled to a certain extent, the prevention and treatment effect reaches 41.23%, the growth indexes such as root length and root thickness are remarkably improved, and the yield increasing effect is achieved.
Owner:JILIN AGRICULTURAL UNIV

Compound preparation for improving digestibility of dry coconut shreds and feed additive

The invention belongs to the technical field of feed additives, and particularly provides a compound preparation for improving the digestibility of dry coconut shreds, which comprises a compound enzyme preparation, the compound enzyme preparation comprises xylanase with the enzyme activity of 0.5 million U / g to 25 million U / g, glucanase with the enzyme activity of 0.8 million U / g to 200 million U / g, mannase with the enzyme activity of 10,000 U / g to 200 million U / g, cellulase with the enzyme activity of 1.2 million U / g to 25 million U / g, pectinase with the enzyme activity of 10,000 U / g to 25 million U / g, galactosidase with the enzyme activity of 10,000 U / g to 300 million U / g and phytase with the enzyme activity of 0.8 million U / g to 200 million U / g. According to the compound preparation provided by the invention, macromolecular substances such as starch in the dry coconut shreds can be degraded into micromolecular substances which are easy to digest, so that the digestion utilization rate is greatly increased; fat is degraded, fatty acid components such as palmitic acid, oleic acid and lauric acid in the coconut shreds are released, and the effects of reducing blood pressure, promoting digestion and the like are achieved; meanwhile, the generated active substances can improve the disease resistance of animals, improve the health state of organisms, improve the nutritional value of the dried shredded coconut and increase the variety of unconventional feed raw materials.
Owner:WUHAN SUNHY BIOLOGICAL +1

Preparation process and application of magnolol-loaded plant exosome

The invention discloses a preparation process and application of magnolol-loaded plant exosomes, and relates to the technical field of plant exosomes. Magnolol is extracted from a magnolia officinalis plant material through ultrasonic assistance, the plant exosomes are obtained from fresh ginger by using an ultracentrifugation method, and the plant exosomes are further modified through palmitic acid and polyethylene glycol, so that the magnolol-loaded plant exosomes are obtained. And finally, preparing the magnolol-loaded plant exosome by virtue of an incubation method. The magnolol can be protected from being damaged by gastric acid and digestive enzymes through membrane structure wrapping of the plant exosome, the stability of the magnolol in the digestive tract is improved, and it is further verified through mouse experiments that the magnolol-loaded plant exosome can be beneficial to regulation of intestinal flora.
Owner:GUANGZHOU HONSEA SUNSHINE BIOTECH CO LTD

Cyclic tetrapeptide derivative as well as preparation method and application thereof

The invention relates to a cyclic tetrapeptide derivative as well as a preparation method and application thereof. The structural formula of the cyclic tetrapeptide derivative is shown as a formula (I), and R is selected from C7-C19 alkyl and C7-C19 unsaturated chain alkyl. The cyclic tetrapeptide derivative or the salt or the stereoisomer thereof provided by the invention can improve the contents of hyaluronic acid, silk protein and alpha-crystal protein of epidermal cells, so that the skin barrier can be effectively enhanced, the obvious repairing and improving effects on the skin are achieved, and compared with palmitic acid tetrapeptide-10, the cyclic tetrapeptide derivative or the salt or the stereoisomer thereof has better stability and safety, and can be used for preparing a medicine for treating skin diseases. And when being used in cosmetics, the composition can play a better role in repairing and enhancing the skin barrier, and has a better improvement effect on the skin. # imgabs0 # (I)
Owner:GUANGZHOU CONGEN PHARMATEC CO LTD

InDel molecular marker primer for identifying soybeans with high palmitic acid content and application of InDel molecular marker primer

The invention discloses an InDel molecular marker primer for identifying soybeans with high palmitic acid content and application of the InDel molecular marker primer. The nucleotide sequence of an upstream primer of the InDel molecular marker primer is as shown in SEQ ID NO.1, and the nucleotide sequence of a downstream primer of the InDel molecular marker primer is as shown in SEQ ID NO.2. Aiming at a QTLqPA21 interval, in combination with amphiphilic re-sequencing data, an Indel site with a difference basic group greater than 15 bp is screened out, and an InDel molecular marker is designed aiming at basic group deletion existing at Chr025018100. According to the InDel molecular marker, an InDel primer sequence is designed, PCR amplification is carried out, a detection result is observed, and the palmitic acid content phenotype is identified. The primer disclosed by the invention can be used for identifying and screening phenotypes of the palmitic acid content of soybeans, and can be used for rapidly, accurately and effectively breeding soybean varieties with high palmitic acid content, so that the breeding process of crops is accelerated, and the breeding efficiency and success rate are improved.
Owner:INST OF CEREAL & OIL CROPS HEBEI ACAD OF AGRI & FORESTRY SCI

Method for flotation separation of micro-plastics

The invention relates to a method for flotation separation of micro-plastics, and belongs to the field of water body micro-plastic separation. The method comprises the steps that in the presence of a foaming agent, a hydrophobic collecting agent and a water body containing the micro-plastics are mixed, and then the micro-plastics are subjected to bubbling flotation; the hydrophobic collecting agent contains dodecahexaenoic acid, eicosapentaenoic acid, cis-oleic acid, cis-linoleic acid and palmitic acid. The method is simple in procedure, easy to operate, low in cost and high in practicability.
Owner:CENT SOUTH UNIV

Nutritional composition

A nutritional composition comprising sn-2 palmitic acid and A2 beta-casein for use in improving the gut microbiota in a human subject.
Owner:NV NUTRICIA

High-performance reactive asphalt cold patch mixture and preparation process thereof

The invention relates to a high-performance reactive asphalt cold patch mixture and a preparation process thereof. The mixture comprises a sulfonated fatty acid diluent, a graded aggregate, an atomic layer deposition (ALD) modified basalt aggregate and a solid waste-based composite curing agent. The sulfonated fatty acid diluent is prepared by sulfonating oleic acid, linoleic acid and palmitic acid through sulfamic acid, the sulfonation degree is 15-20%, and the sulfonated fatty acid diluent contains an epoxy three-membered ring structure; the 3-5mm aggregate is used as a transition layer to block the caking path of the fine aggregate; the basalt aggregate is subjected to TDMAT and TMA alternate deposition to form a Ti < x > Al < gamma > O < 2 > nano film; the curing agent comprises calcium strontium sulphoaluminate minerals, a titanium gypsum-carbide slag compound and magnesium-loaded lithium slag. During preparation, the modified aggregate, the sulfonated diluent and the curing agent are mixed at normal temperature. The problems that a traditional cold repairing material is poor in low-temperature fluidity and weak in interface bonding are solved, the viscosity at-20 DEG C is smaller than or equal to 450 mPa.s, the 7-day strength is larger than or equal to 5.2 kN, and the cold repairing material is suitable for low-temperature emergency repairing.
Owner:NANJING JINGU SMART MUNICIPAL RES INST CO LTD

Crystallization process of small-particle-size palmitic acid paliperidone

The invention belongs to the technical field of crystal compound preparation, and particularly relates to a crystallization process of small-particle-size palmitic acid paliperidone. The invention discloses a small-particle-size palmitic acid paliperidone crystallization process, solves the problems of large particle size, non-uniform distribution and serious agglomeration of the existing process product, and meets the requirements of long-acting injection bulk drugs. The process comprises the following steps: adding paliperidone palmitate into a specific mixed organic solvent according to a solid-to-liquid ratio of 0.04-0.09 g / g, stirring, dissolving and filtering at 65-75 DEG C, transferring into a high-pressure closed crystallizer, and pressurizing to 1.0-1.5 MPa; cooling and decompressing in sections, stirring, filtering and washing, and drying in vacuum at the temperature of 40-50 DEG C and the vacuum degree of-0.1 MPa to obtain a finished product. According to the invention, the process parameters are accurately controlled, the product is an irregular short rod-like / granular crystal, the particle size is in a normal single peak, the Dv (90) is 7.866-9.514 microns, the HPLC (High Performance Liquid Chromatography) purity is greater than or equal to 99.92%, the yield is greater than or equal to 90.25%, micronization is not needed, the process is stable, the economical efficiency is good, and the industrial application value is realized.
Owner:UNIV OF JINAN

Method for separating oleic acid from byproduct of OPO grease and oleic acid

The invention provides a method for separating oleic acid from a byproduct of OPO grease and oleic acid. The method comprises the following steps: (1) a seed crystal comprises the following components in percentage by mass: 70-100 wt% of stearic acid, 0-20 wt% of palmitic acid triglyceride and 0-15 wt% of glyceryl monostearate or glyceryl monostearate and glyceryl distearate; (2) adding the seed crystal into the OPO by-product according to the addition amount of 10-50wt%, and stirring at the temperature of 70 DEG C under the protection of N2 to obtain crystal slurry; (3) pumping the crystal mush into a crystallization kettle, protecting by N2, stirring, setting the initial temperature of the crystallization kettle to be 70 DEG C, and preserving heat for 1 hour; reducing the temperature from 70 DEG C to 55 DEG C at 3-5 DEG C / h; the temperature is reduced from 55 DEG C to 20 DEG C at the speed of 2-3 DEG C / h; finally, the temperature is reduced to 15-8 DEG C from 20 DEG C at the speed of 1-2 DEG C / h, heat preservation is conducted for at least 5 h, and a crystal substance is obtained; carrying out filter pressing on the crystal substance at the pressure of 0.6 MPa and the temperature of 8-15 DEG C to obtain a filter cake and filtrate; according to the method, the OPO byproduct is used as a raw material to recover high-quality oleic acid, the purity of the oleic acid is more than 80%, and the recovery rate is more than 60%.
Owner:ZANYU TECH GRP CO LTD

GC-MS (Gas Chromatography-Mass Spectrometer) quality detection method of traditional Chinese medicine composition capable of dredging

The invention provides a GC-MS (Gas Chromatography-Mass Spectrometer) quality detection method for a pulse-invigorating and blood-glucose-reducing traditional Chinese medicine composition. The detection method has the advantages of simple and convenient operation steps, accurate detection and high stability. According to the preparation method, volatile components in the blood-glucose-promoting and blood-glucose-reducing granules are determined, and 15 batches of content determination shows that the content of atractylenol in the blood-glucose-promoting and blood-glucose-reducing granules is 0.0205 to 0.1893 mg / g, the content of beta-eudesmol in the blood-glucose-promoting and blood-glucose-reducing granules is 0.0643 to 0.5737 mg / g, the content of palmitic acid in the blood-glucose-promoting and blood-glucose-reducing granules is 0.7319 to 5.1163 mg / g, the content of ferruginol in the blood-glucose-promoting and blood-glucose-reducing granules is 0.0743 to 0.2356 mg / g, and the content of tanshinone IIA in the blood- The detection method can be used as an internal control quality detection standard of the product to further guarantee the product quality. And the detection method can also be used for identifying the chemical components of the traditional Chinese medicine composition for dredging collaterals and reducing blood glucose, and has a good market prospect.
Owner:BAODING BUCHANG TIANHAO PHARMA +1

Nutrient composition for improving muscle function and application

The invention relates to the technical field of nutritional foods, and particularly discloses a nutritional composition for improving muscle functions and application. The nutritional composition for improving the muscle function, provided by the invention, is prepared from the following components in parts by mass: 40 to 60 parts of 1, 3-dioleic acid-2-palmitic acid triglyceride and 20 to 70 parts of 1-oleic acid-2-palmitic acid-3-linoleic acid triglyceride. A specific amount of OPO and OPL are compounded, and the two components have a synergistic effect, so that the exercise amount and the ATP content of an organism are remarkably increased, sarcopenia is relieved by improving energy metabolism, the muscle function is improved, and the food has a wide application prospect in the field of food and is worthy of popularization and application. The food can be used in health-care food, formula food for special medical purposes, infant formula food or special diet food.
Owner:JUNLEBAO DAIRY GRP CO LTD

Molecular marker of locus qFAC.C9-1 remarkably associated with fatty acid components of cabbage type rape seeds and application of molecular marker

The invention belongs to the technical field of molecular biology and genetic breeding, and discloses a molecular marker of a locus qFAC.C9-1 remarkably associated with a fatty acid component of a cabbage type rape seed and application of the molecular marker. A locus qFAC.C9-1 remarkably associated with fatty acid components of rape seeds and a peak SNP (Single Nucleotide Polymorphism) marker Bn-scaff171901-p9206 of the locus qFAC.C9-1 are positioned at the 3rd, 592nd and 310th basic groups of a chromosome of a reference genome C09 of the rape DarmorV4.1, and 8.6% of phenotypic variance can be explained on average. When the PARMS marker designed by the SNP is used for detecting rape germplasm resources, the operation is simple and convenient, the typing is clear, the average content of arachidonic acid and erucic acid of AA genotype material seeds is lower than that of GG genotype material seeds, and the content of linoleic acid, oleic acid, palmitic acid and stearic acid is higher, so that the PARMS marker has a very good selection effect on the fatty acid components of the rape seeds.
Owner:OIL CROPS RES INST CHINESE ACAD OF AGRI SCI

A stable long-acting composition of paliperidone palmitate and preparation method thereof

The present invention belongs to the field of pharmaceutical preparations, and specifically relates to a stable long-acting composition of paliperidone palmitate and a preparation method thereof. The preparation method of the stable long-acting composition of paliperidone palmitate comprises: preparing a suspension of paliperidone palmitate; pouring the suspension into a double-chamber syringe and freeze-drying; after the double-chamber syringe is plugged for the first time, a reconstitution liquid is poured into a separate compartment; the double-chamber syringe is plugged for the second time to obtain the long-acting composition of paliperidone palmitate. The long-acting composition of paliperidone palmitate of the present invention uses paliperidone palmitate as an effective ingredient, which is filled in a syringe with a double-chamber structure, is easy to use, and has good redispersibility and physical stability.
Owner:YANTAI INSTITUTE OF PHARMACEUTICAL SCIENCE

Botanical attractant for camellia weevils and application of botanical attractant

The invention discloses a botanical attractant for camellia weevils and application of the botanical attractant, and belongs to the technical field of plant disease and pest control. The botanical attractant provided by the invention comprises palmitic acid and / or phytol. The palmitic acid and / or the phytol have / has remarkable and efficient attraction activity on the camellia weevils, and are suitable for detecting the population trend of the camellia weevils, efficient attraction control and the like. Compared with a traditional method for chemically preventing and treating the camellia weevils at the present stage, the method for preventing and treating the camellia weevils through the plant source attractant is milder, more efficient, environmentally friendly and free of toxic and side effects, and important value can be provided for market application and application and popularization.
Owner:HUNAN PLANT PROTECTION INST

Preparation method of phase change material composite building thermal insulation material based on porous structure

The invention relates to the technical field of building materials, and discloses a preparation method of a phase change material composite building thermal insulation material based on a porous structure. 13 to 18 parts of modified diatomite; 9 to 13 parts of nano cellulose aerogel; 7 to 11 parts of food-grade palmitic acid; 8 to 13 parts of microcapsule bio-based PCM; 0.9 to 1.4 parts of modified graphene; 11 to 15 parts of environment-friendly polylactic acid; 7 to 10 parts of montmorillonite; 1-2 parts of nano silicon dioxide; by compounding the expanded perlite, the modified diatomite and the nanocellulose aerogel, a basic framework with high porosity and low heat conductivity is constructed, heat conduction is effectively blocked, by introducing food-grade palmitic acid and microcapsule bio-based PCM, the material is endowed with heat storage and temperature regulation functions, phase change latent heat is improved, and the thermal conductivity of the material is improved. By adding modified graphene and nano silicon dioxide, an efficient heat conduction network and a heat insulation structure are formed, and the heat conductivity coefficient of the composite building heat preservation material is further reduced.
Owner:GUANGZHOU QI HI-TECH MATERIALS TECHNOLOGY CO LTD

Application of vitamin D3 in improvement of trophoblast proliferation inhibition

The invention discloses application of vitamin D3 in preparation of a product for improving trophoblast proliferation inhibition. The research proves that the vitamin D3 can obviously improve the proliferation inhibition of palmitic acid on human trophoblast cells; the vitamin D3 can reduce palmitic acid induced cell active oxygen level up-regulation; vitamin D3 can up-regulate expression of Nrf-2, HO-1 mRNA and protein in cells induced by palmitic acid. Vitamin D3 can improve palmitic acid induced human trophoblast cell proliferation inhibition by activating an Nrf2 / HO-1 pathway. The invention provides a new product for improving the proliferation inhibition of palmitic acid on human trophoblast cells, and has a good clinical application prospect.
Owner:CHONGQING MEDICAL UNIVERSITY

Graphene composition

This invention provides a safe, environmentally friendly and solvent free method for dispersing graphene into polymeric compositions. In this process solid particles of graphene in a fatty acid matrix are mixed into the polymeric composition. The use of these solid graphene containing particles does not create dust while being mixed into the polymer and can much more easily be mixed into the polymer. Since fatty acids, such as stearic acid, palmitic acid, and oleic acid, are frequently incorporated into the polymeric formulations used in making a wide variety of products, this technique also offers a good method for introducing the fatty acid into the polymeric formulation. In such fatty acid containing polymeric formulations this technique also offers the advantage of not introducing unwanted solvents or agents into the formulation.
Owner:ROCKHILL ALVIN T +1

Nutritional composition for promoting absorption of fatty acid and mineral substances and application

The invention belongs to the field of functional substance research, and particularly relates to a nutritional composition for promoting absorption of fatty acid and mineral substances and application. The nutritional composition provided by the invention comprises necessary active ingredients shown as the following (I) and (II): (I) 1, 3-dioleic acid-2-palmitic acid triglyceride; (II) a milk fat globule membrane, and / or, 2 '-fucosyllactose; moreover, in the nutritional composition, the mass ratio of the necessary active component shown in (I) to the necessary active component shown in (II) is (5-10): (0.5-10). The combination of OPO and MFGM and / or 2 '-FL provided by the invention can be beneficial to promoting the absorption of the body to fatty acids and mineral substances, and especially can be beneficial to promoting the transmembrane transport capability of intestinal cells of the body to fatty acids and mineral substances, so that the absorption efficiency is improved.
Owner:FEIHE (AR HORQIN BANNER) DAIRY CO LTD +1

Application of recombinant protein DEL-1 in preparation of drugs for resisting pancreatic beta cell inflammation

The invention relates to the technical field of biological pharmacy, in particular to application of a recombinant protein DEL-1 in preparation of a medicine for resisting pancreatic beta cell inflammation. The recombinant protein DEL-1 has a remarkable inhibition effect on pancreatic beta cell inflammatory response induced by high glucose and high fat. Experiments show that in an islet beta cell inflammation model constructed by combining high glucose with palmitic acid, DEL-1 can significantly reduce the expression level of inflammatory factors such as IL-1beta, IL-6, TNF-alpha and the like. The DEL-1 is proved to have a definite effect of resisting pancreatic beta cell inflammation.
Owner:TIANJIN INTEGRATED TRADITIONAL CHINESE & WESTERN MEDICINE HOSPITAL (TIANJIN NANKAI HOSPITAL) +1

A thermoelectric hydrogel composite dressing for promoting repair of diabetic ulcers and loading of targeted modified exosomes and a preparation method thereof

ActiveCN119925682BBandagesWound lesionUltraviolet lights
The application provides a thermoelectric hydrogel composite dressing for promoting repair of diabetic ulcers and loading of targeted modified exosomes and a preparation method, which comprises the following steps: preparing methacrylated hyaluronic acid; preparing polyether F127 diacrylate; co-incubating exosomes with palmitic acid grafted targeting peptides to prepare targeted modified exosomes; mixing the methacrylated hyaluronic acid, the polyether F127 diacrylate, a photosensitizer, the targeted modified exosomes and an electrolyte, and crosslinking under ultraviolet light to form a composite gel. The composite dressing is a novel composite dressing for thermoelectric stimulation and exosome treatment. On one hand, the dressing generates a wireless and passive electric field to simulate the endogenous electric field in the wound, promote directional migration of skin cells, accelerate reepithelialization and dermal formation; on the other hand, the dressing releases exosomes to precisely target blood vessels of a wound lesion, reverse endothelial dysfunction in a high-sugar environment and promote angiogenesis, and effectively solves the problems in repair and regeneration of diabetic ulcer wounds.
Owner:ZHEJIANG UNIV

Weather-resistant heat storage and insulation coating for energy storage equipment and preparation method of weather-resistant heat storage and insulation coating

The invention relates to a weather-resistant heat storage and heat preservation coating for energy storage equipment and a preparation method of the weather-resistant heat storage and heat preservation coating, and belongs to the technical field of coatings, modified composite resin is prepared from epoxy resin, organic silicon prepolymer, fluorocarbon resin, trifluoropropyl polydimethylsiloxane and other materials, and good film-forming property, adhesive force, weather resistance, binding property and energy storage and heat insulation property are provided. Paraffin, a Ti3AlC2MAX phase ceramic material, palmitic acid and polyphosphorylcholine ethylene glycol acrylate are adopted to prepare a composite energy storage material, the composite energy storage material is coated with nano-silica to obtain a nano-silica coated composite energy storage material, and the composite energy storage material is matched with components such as a weather-proof filler and a heat-insulating filler to be used according to a certain proportion. The coating has good weather resistance, corrosion resistance, heat storage and heat preservation performance, adhesive force, mechanical performance and the like.
Owner:CHINA PAINT XINFENG CO LTD

Composition for promoting differentiation of intestinal immune cells as well as preparation method and application of composition

The invention provides a composition for promoting differentiation of intestinal immune cells as well as a preparation method and application of the composition. According to the composition, 1, 3-dioleic acid-2-palmitic acid triglyceride and breast milk oligosaccharide are used in a combined manner, so that monocytes can be effectively promoted to differentiate into intestinal macrophages, and inflammation is reduced to a certain extent. After the monocytes are differentiated into the intestinal macrophages, the intestinal immune homeostasis and intestinal microbiota inflammatory response can be regulated, so that the mucosal immune homeostasis and intestinal epithelial cell barrier function are maintained. Therefore, the composition provided by the invention can improve the intestinal immune barrier by promoting the monocytes to differentiate into the intestinal macrophages, and provides a new thought for improving the early intestinal barrier of infants through nutritional supplement.
Owner:AUSNUTRIA DAIRY CHINA

Mitochondrial uncoupling inhibitor sustained-release nanodot, preparation method thereof and application of nanodot in type 2 diabetes mellitus

The invention relates to a mitochondrial uncoupling inhibitor sustained-release nanodot, a preparation method thereof and application of the nanodot in type 2 diabetes mellitus, and belongs to the technical field of nano-drugs. According to the preparation method disclosed by the invention, glycine and genipin are subjected to Schiff reaction to prepare the slow-release nanodot, and the slow-release nanodot is of a monodisperse spherical structure, has surface negative charges, and can slowly release genipin under physiological conditions, so that the mitochondrial protection effect of the genipin is fully exerted. The mitochondrial uncoupling inhibitor slow-release nanodot prepared by the invention can obviously improve the mitochondrial membrane potential, increase the cell ATP content, effectively inhibit mtDNA release under the stimulation of IL-1beta and palmitic acid, effectively inhibit STING inflammation pathway activation under the stimulation of IL-1beta and PA, obviously reduce pancreatic beta cell apoptosis, obviously relieve endoplasmic reticulum stress, and can be used for preparing the mitochondrial uncoupling inhibitor slow-release nanodot. The T2DM mouse blood sugar is obviously reduced, the glucose tolerance dose and the insulin sensitivity are improved, and good biocompatibility is achieved.
Owner:CENT SOUTH UNIV

Divalent salt resistant filtrate reducer for drilling fluid

The invention relates to the technical field of petroleum drilling fluid loss reduction, and discloses an anti-divalent salt fluid loss agent for drilling fluid, which is prepared by the following steps: step 1, beta-cyclohexylamine and 6-chloro-1-hexene are subjected to a reaction to obtain alkenyl beta-cyclohexylamine; step 2, initiating polymerization of alkenyl beta-cyclopentadiene, a hyperbranched monomer pentaerythritol triallyl ether and 2-acrylamide-2-methylpropanesulfonic acid under the action of azobis (isobutylamidine hydrochloride), so as to obtain an intermediate A; 3, 3-dimethylamino-1-propylamine and palmitic acid are subjected to a reaction, and an intermediate 2 is obtained; 4, the intermediate 2 and benzyl chloride are subjected to a reaction, and quaternary ammonium salt modified fatty acid is obtained; and 5, stirring and mixing the intermediate A, quaternary ammonium salt modified fatty acid and coupling agent modified walnut powder to obtain the divalent salt resistant filtrate reducer for the drilling fluid. The anti-divalent salt filtrate reducer for the drilling fluid has a relatively good anti-divalent salt effect.
Owner:HUIXIAN SHANSHUI CHEM TECH CO LTD

Bottom plate for anti-crack laminated slab and preparation method of bottom plate

PendingCN120398495ACarboxylic acidSlurry
The invention discloses a bottom plate for an anti-crack laminated slab and a preparation method of the bottom plate, and belongs to the technical field of laminated slabs. The bottom plate for the anti-crack laminated slab is obtained by pouring and curing 4D steel fiber composite concrete slurry; the 4D steel fiber composite concrete slurry is prepared from the following raw material components in parts by mass: 20 to 35 parts of cement, 5 to 15 parts of mineral admixture, 25 to 40 parts of acrylate copolymer emulsion, 50 to 65 parts of sand, 0.05 to 0.2 part of defoaming agent, 0.1 to 0.25 part of polycarboxylic acid water reducing agent, 0.05 to 0.2 part of early strength agent and 0.4 to 0.9 part of modified 4D steel fiber, the acrylate copolymer emulsion is prepared from lauryl methacrylate, acrylamide, butyl perfluoroacrylate, 1H, 1H, 2H, 2H-perfluorodecyl acrylate, 1, 3-dimethylamino allyl phosphoric acid, 2-allylfuran, an initiator, a solvent and a solvent; aluminum palmitate is adopted as the defoaming agent; the modified 4D steel fiber is obtained by modifying maleimide siloxane.
Owner:YIJIANWANG TECH CO LTD

Polyester resin for triglycidyl trimesic acid ester curing powder coating and preparation method of polyester resin

The invention discloses polyester resin for a triglycidyl trimesic acid ester curing powder coating and a preparation method of the polyester resin. The polyester resin is obtained by esterification and condensation polymerization of trimesic acid, terephthalic acid, glycidyl methacrylate, glycidyl neodecanoate, palmitic acid, neopentyl glycol and behenyl alcohol. The cleaning agent comprises the following components in parts by mass: 5-15 parts of trimesic acid; 10 to 25 parts of terephthalic acid; 3 to 17 parts of glycidyl methacrylate; 8 to 12 parts of glycidyl neodecanoate; 3 to 7 parts of palmitic acid; 5 to 19 parts of neopentyl glycol; and 3 to 7 parts of behenyl alcohol. According to the invention, terephthalic acid and neopentyl glycol are used as framework monomers, and glycidyl methacrylate and glycidyl neodecanoate are used for modifying polyester resin, so that an obtained coating is higher in gloss and better in fineness; behenyl alcohol and palmitic acid are adopted to reduce the softening point of the polyester resin, reduce the difference between a curing agent and polyester in softening flow, increase the wettability of a film forming matter to pigments, fillers and a base material, and improve the gloss and fineness of a coating.
Owner:ZHEJIANG CHUANHUA TIANSONG NEW MATERIAL CO LTD