54 results about "Mixed fatty acid" patented technology

The invention relates to high-barrier polyester and a preparation method thereof, and belongs to the field of polymers. The method comprises the following steps: soaking sodium-based MMT in mixed fatty acid, stirring, mixing with a conventional water bottle grade slice at a high speed, and finally melting and granulating the blended material by using double screws to obtain the high-barrier master batch. A known polyester product is mixed with the prepared high-barrier master batch, and the high-barrier polyester bottle is produced on an injection molding machine.

The invention relates to the technical field of natural product extraction, in particular to a process for separating and extracting nervonic acid from xanthoceras sorbifolia bunge. The preparation method comprises the following steps: extracting xanthoceras sorbifolia bunge kernels to prepare xanthoceras sorbifolia bunge oil; the xanthoceras sorbifolia bunge oil is filtered and refined through a composite polyethersulfone membrane, and mixed fatty acid is prepared; mixing fatty acids to prepare nervonic acid. Molybdenum disulfide and lithium fluoride treated by hydrochloric acid are jointly dispersed in a solution, and after a composite nano material prepared through treatment of molybdenum disulfide and lithium fluoride is used for treating a polyether sulfone membrane, the obtained composite polyether sulfone membrane does not generate pollution and has an adsorption effect on impurities in xanthoceras sorbifolia bunge oil; when the xanthoceras sorbifolia bunge oil is filtered by the polyether sulfone membrane, other impurities are adsorbed, the xanthoceras sorbifolia bunge oil is refined, the content of an extraction solvent and other impurities in the xanthoceras sorbifolia bunge oil is reduced, and the extraction rate and purity of nervonic acid extracted from the xanthoceras sorbifolia bunge oil are improved.

The invention provides a CO2 tall oil-resistant imidazoline Mannich base corrosion inhibitor, a preparation method thereof and a composite corrosion inhibitor. The imidazoline Mannich base corrosion inhibitor with a hydrophilic group and a hydrophobic group is obtained by synthesizing an imidazoline ring from tall oil mixed fatty acid and organic polyamine and then condensing arone and trioxymethylene with a terminal amino group of a side chain of the imidazoline ring. According to the CO2-resistant imidazoline corrosion inhibitor, the CO2-resistant performance of the imidazoline Mannich base corrosion inhibitor in CO2 can be improved by utilizing the synergistic adsorption and isolation effects of imidazole rings with different alkyl structures and Mannich base groups in an acid medium. The imidazoline Mannich base is compounded with the surfactant O-20 and the solubilizer PEG20000, so that the corrosion inhibition performance of the corrosion inhibitor can be further improved. The product meets the environmental protection requirements of enterprises and is beneficial to industrial popularization and application.

The invention relates to the technical field of separation and purification, in particular to a method for recovering cis-15-tetracosenoic acid from an acer truncatum seed oil byproduct, which comprises the following steps: selecting the acer truncatum seed oil byproduct, crushing, sieving, washing, adding modified attapulgite and beta-cyclodextrin, stirring and adsorbing at constant temperature, and filtering; preparing the modified attapulgite; adding a KOH-EtOH solution containing lipase and polyethylene glycol into a pretreated product for refluxing, and adding a saturated saline solution for refluxing; standing and layering the reaction liquid, and extracting, acidifying, washing, drying and distilling an organic phase to obtain mixed fatty acid; and carrying out composite purification to obtain a pure cis-15-tetracosenoic acid product. According to the method, the purity and the extraction rate of the cis-15-tetracosenoic acid are remarkably improved, the oxidation, heat and storage stability of the product is enhanced, the color is improved, and the comprehensive application performance is better.

The invention discloses a method for separating stearic acid lactone from mixed fatty acid, which comprises the following steps: dispersing an oleic acid isomerization hydrogenation product in an organic solvent which is one of normal hexane, methanol, ethanol, ethyl acetate and acetonitrile, then carrying out freezing crystallization, then carrying out solid-liquid separation, taking the liquid, and carrying out reduced pressure distillation to obtain the stearic acid lactone. The stearic acid lactone is obtained. The method for separating the stearic acid lactone from the mixed fatty acid has the advantages of simplicity in operation, high separation efficiency, low energy consumption, mild conditions, high purity of the separated stearic acid lactone and the like, and is suitable for large-scale industrial application.

The invention relates to the technical field of pharmaceutical preparations, and particularly discloses an anti-inflammatory analgesic indometacin long-acting suppository and a preparation method thereof.The suppository is composed of indometacin sustained-release microspheres and a modified fatty matrix; eudragit RS100 / RL100 is used as a compound framework of the sustained-release microspheres, the sustained-release microspheres are prepared through a spherocrystal granulation process, the modified fatty matrix is prepared from a mixed fatty glyceride compound matrix sustained-release aid, a three-dimensional suspending dispersant and the like through melting, pre-crystallization and high-speed homogenization processes, and the three-dimensional suspending dispersant contains modified nano silicon dioxide, glycerin monostearate and beewax. According to the invention, a microsphere-matrix dual controlled release system is constructed, so that burst release of drugs is eliminated, and long-acting stable release is realized; the microspheres are prevented from settling and agglomerating through a physical locking mechanism, and the storage stability of the preparation is improved by matching with a dual anti-oxidation system; meanwhile, rectal mucosa stimulation is reduced, the preparation process is simple, the quality is controllable, and the composition is suitable for anti-inflammation and analgesia of various diseases and has a wide clinical application prospect.

The utility model discloses a multi-filtering device which comprises a filtering device body, and the filtering device body comprises a filtering cylinder and a filtering plate body connected in the filtering cylinder; the filter plate body comprises multiple layers of filter plates and sealing rings connected to the peripheries of the multiple layers of filter plates, and the sealing rings are connected into the filter cartridge and fixedly connected with the inner wall of the filter cartridge in a sealing manner; the bottom of the sealing ring is connected with a partition ring, the bottom of the partition ring extends in the vertical downward direction, and a gap is formed between the bottom of the partition ring and the inner wall of the filter cartridge. By arranging the sealing ring and the partition ring, the mixed fatty glyceride cannot be in contact with the cylinder wall below the filter plate body before and after filtration, so that the mixed fatty glyceride cannot be adhered to the cylinder wall, the structure is simpler, and the overall cost is effectively reduced.

The present application relates to a kind of coal slime collector preparation method using kitchen waste oil, comprising the kitchen waste oil after being pretreated with water, emulsifier is mixed, as carbon source configuration first culture medium, Bacillus and Rhodococcus species are inoculated in it and carry out aerobic fermentation, obtain refined oil, and as carbon source configuration second culture medium, Candida species are inoculated in it and carry out aerobic fermentation, obtain mixed fatty acid, and as carbon source configuration third culture medium, Yarrowia species are inoculated in it and carry out micro-aerobic fermentation, obtain alkane mixture;Emulsified oil and / or refined oil are as carbon source configuration fourth culture medium, Pseudomonas species are inoculated in it and carry out aerobic fermentation, obtain rhamnolipid;Alkane mixture is mixed with rhamnolipid, obtain coal slime collector.The present application develops a new type of green, good coal slime collector by constructing multistage series biological transformation process.

The invention discloses a method for detecting glyceride and fatty acid composition ratio in mixed fatty acid glyceride by thin-layer chromatography-gas chromatography coupling, and the method mainly comprises the following steps: 1) internal standard solution is prepared; 2) mixed fatty acid glyceride need testing solution is prepared; 3) thin-layer chromatography is used to separate mixed fatty acid glyceride; 4) fatty acid methyl ester is prepared; 5) gas chromatography is used to detect, and the fatty acid composition of monoglyceride, diglyceride and triglyceride and the ratio of each fatty acid are determined respectively; and 6) the sum of the fatty acids of each monoglyceride, diglyceride and triglyceride obtained after data analysis in step 5) is divided by the fatty acid sum of monoglyceride, diglyceride and triglyceride, and the composition ratio of each monoglyceride, diglyceride and triglyceride in mixed fatty acid glyceride is obtained. The method of the present invention is simple and efficient to operate, and is quantitatively accurate, and methyl esterification reaction conditions are mild, equipment is simple, and no special equipment is required.

The invention relates to the field of wood modification, in particular to modified wood and a modification method thereof. The method comprises the following steps: (1) drying wood to be modified to constant weight to obtain dried wood; (2) the dried wood is placed in steeping liquor to be treated, and steeped wood is obtained; the steeping liquor comprises any one of steeping liquor I and steeping liquor II; the impregnation liquid I comprises silicate and organic acid I; the impregnation liquid II comprises organic acid II, mixed fatty acid methyl ester and wax. On the premise of ensuring simple operation steps, the porosity of the wood can be reduced, and the dimensional stability, high humidity resistance and salt resistance of the wood can be improved.

The invention belongs to the technical field of food processing, and relates to a method for enriching unsaturated fatty acid in tussah chrysalis oil through an ultrasonic-assisted beta-cyclodextrin inclusion method. Preparing fresh tussah pupa into tussah pupa powder; performing supercritical CO2 extraction; the method comprises the following steps: weighing tussah chrysalis oil, respectively carrying out saponification reaction on the tussah chrysalis oil and a saponification medium, adjusting pH by hydrochloric acid, and drying to remove other impurities to obtain tussah chrysalis oil mixed fatty Adding the tussah chrysalis oil into a beta-cyclodextrin solution, carrying out ultrasonic treatment on the mixed solution, freezing, unfreezing at room temperature, carrying out reduced-pressure suction filtration to obtain a white solid, washing, centrifuging, combining supernate, and drying the solid part to constant weight to obtain white powder, namely a beta-cyclodextrin-tussah chrysalis oil compound; and adding petroleum ether, stirring, carrying out reduced pressure suction filtration, and recovering the petroleum ether by using a rotary evaporator to obtain the residual liquid, namely the tussah chrysalis oil unsaturated fatty acid extract.

The invention relates to wide-temperature-range modified natural ester insulating oil and a molecular structure design method thereof, and the molecular structure of the wide-temperature-range modified natural ester insulating oil with different ester chain structures is obtained by converting natural ester into mixed fatty acid methyl ester with the chain length of C8-C18, then blending the proportion and introducing groups for molecular modification. According to the design method, natural ester insulating oil molecules with different ester chain structures are constructed, and the influence rule of the fatty acid methyl ester carbon chain length proportion, the C = C double bond number and the modification group on the flash point and pour point of the natural ester insulating oil is obtained; the obtained wide-temperature-range modified natural ester insulating oil not only keeps the high flash point of the natural ester insulating oil, but also has the characteristic of low pour point, so that the working temperature range of the natural ester insulating oil is widened, and the defect that a natural ester insulating oil transformer operates under high-altitude, cold regions and extreme weather conditions is overcome; the preparation process is simple, reaction conditions are mild, the environment is not polluted, and batch production is easy.

The embodiment of the application discloses a flotation reagent preparation method, a flotation reagent and a flotation method of a rare earth ore. The flotation reagent preparation method is characterized in that the method comprises the following steps: mixing a plurality of flotation reagents to obtain a mixed fatty acid collector; adding a sodium hydroxide solution to the mixed fatty acid collector to obtain a collector solution; and electrolyzing the collector solution and oxidizing the collector solution to make the collector solution generate nanobubbles and hydroxyl radicals, thereby obtaining a flotation reagent. The flotation reagent preparation method can simultaneously realize dispersion activation and in-situ oxidation modification of the fatty acid collector, can generate hydroxyl radicals without additional addition of a Fenton reagent, and can avoid problems such as impurity pollution of ore slurry and unstable oxidation effect caused by an exogenous reagent.

The invention discloses a method for extracting and separating nervonic acid from vegetable oil, and belongs to the technical field of nervonic acid extraction and separation. The extraction and separation method of nervonic acid comprises the following steps: (1) mixing vegetable oil with an alkaline ethanol solution, and carrying out saponification reaction to obtain fatty acid salt; (2) adding an acid solution into the fatty acid salt, stirring to fully acidify the fatty acid salt, standing for layering, separating an oil phase, and washing to be neutral to obtain mixed fatty acid; (3) performing macroporous resin column chromatography separation and purification on the mixed fatty acid, and collecting eluent to obtain a chromatography sample; and (4) mixing the chromatography sample with a solvent, recrystallizing, and drying to obtain nervonic acid with the content of 95% or above. The method provided by the invention has the advantages of simple process steps, no need of special production equipment, good extraction stability and repeatability, high nervonic acid extraction purity and high yield.

An ester for refrigerator oil, which contains a first ester that is an ester of a polyhydric alcohol and a C6-9 fatty acid, a second ester that is an ester of pentaerythritol and a fatty acid, and a third ester that is an ester of pentaerythritol, a dicarboxylic acid and a fatty acid, the fatty acid constituting the second ester and the fatty acid constituting the third ester are both mixed fatty acids of at least one selected from the group consisting of branched butyric acid, branched pentanoic acid, and linear pentanoic acid, and any one selected from branched caprylic acid and branched nonanoic acid.

To provide an oily liquid cosmetic having excellent temporal stability and exhibiting superior properties in both thickness upon application and smoothness in spreading.SOLUTION: An oily liquid cosmetic comprising the following components (A)-(C): (A) an oil-soluble polyurethane, (B) fumed silica, and (C) a dextrin fatty acid ester in which a fatty acid moiety is derived from a mixed fatty acid of branched saturated fatty acid and linear saturated fatty acid.SELECTED DRAWING: None

The invention relates to the technical field of enzymatic preparation of grease, in particular to a method for enzymatic preparation of special grease for infant formula milk powder, which comprises the following steps: constructing a pH response type interface biocatalysis system, and synthesizing and enriching functional ester; the preparation method comprises the following steps: preparing an sn-2 palmitic acid diglyceride intermediate based on alcoholysis reaction, and reacting the sn-2 palmitic acid diglyceride intermediate with mixed fatty acid to synthesize the composite structure lipid; and preparing the target mixed grease from the functional ester, the composite structure grease and the fat-soluble vitamin by adopting a low-temperature high-speed shearing and homogenizing technology. According to the method for preparing the grease special for the infant formula milk powder through the enzyme method, pH response type magnetic nano immobilized lipase is prepared, the enzyme activity is controllable, and the grease is recycled and reused through the dual mechanisms of magnetic separation and pH induced aggregation; a fat-soluble vitamin-structural fat-essential fatty acid composite synergistic system is constructed, the functions of energy supply, mineral absorption and micronutrient supplementation are achieved, and a target grease product is purified by adopting a multi-stage molecular distillation step.

The invention provides pentaerythritol ester and a preparation method thereof. The preparation method comprises the following steps: mixing mixed fatty acid and pentaerythritol according to the molar ratio of carboxyl to hydroxyl of (1-1.5): 1, irradiating by using ultraviolet light under 0.01-0.09 MPa, and carrying out esterification reaction under the condition of ultrasonic treatment to obtain pentaerythritol ester; wherein the mixed fatty acid comprises monobasic fatty acid and dibasic fatty acid, the monobasic fatty acid is at least two of C5-C10 monobasic fatty acid, and the dibasic fatty acid is at least one of C5-C9 dibasic fatty acid. According to the preparation method, the reaction esterification rate can be remarkably increased, the reaction time is shortened, the process is simple, and the large-scale application prospect is good.

The application provides a hard-bubble high-flame-retardant phase change polyurethane material and a preparation method thereof, and belongs to the technical field of building materials. The preparation method is mixing polyether polyol, calcium carbonate, a gel phase change material, a catalyst, a foaming agent, a foam stabilizer, a plasticizer, a chain extender, ammonium polyphosphate, an antioxidant DNP and an ultraviolet absorber, then adding isocyanate, rapidly stirring, freely foaming, and aging to obtain the hard-bubble high-flame-retardant phase change polyurethane material. The gel phase change material is prepared by using mixed fatty acid formed by mixing myristic acid and octadecanoic acid as core material, using sodium silicate and tetraethyl silicate as aerogel wall material, using the hydrophobic end of an emulsifier to include the core material, and using the hydrophilic end of the emulsifier to combine with the aerogel wall material. The application effectively reduces the thermal conductivity of the prepared hard-bubble high-flame-retardant phase change polyurethane material, reduces heat loss caused by heat transfer, and improves temperature adjustment and control capacity.

The invention relates to a method for preparing high-purity oleic acid from tea oil based on coupling of a molecular distillation technology and a urea embedding technology in the technical field of deep processing of edible oil and fat. The method comprises the following steps: firstly, microfiltering the tea oil by using a 0.1-0.5 mu m membrane to remove impurities; then preparing mixed fatty acid; mixing the mixed fatty acid with a urea-ethanol solution according to the ratio of fatty acid to urea being 1: (1.2-1.8), stirring at 45-50 DEG C for 2-3 hours, cooling to-15 to-5 DEG C, crystallizing for 1-14 hours, separating and taking a liquid phase; and finally, treating the liquid phase by a wiped-film molecular distillation system to obtain high-purity oleic acid. According to the method, oleic acid enrichment is achieved, and meanwhile a large amount of heat-sensitive active ingredients are effectively prevented from being oxidized and decomposed.

The invention provides a production method of modified dibutyltin dilaurate, and relates to the technical field of chemical engineering. The method comprises the following steps: sequentially adding coconut oil acid, dibutyltin dichloride and ethanol raw materials into a reactor, and stirring to obtain a mixed solution; adding a catalyst into the mixed solution, and stirring and reacting at 40 DEG C to obtain a first reaction solution; adding a sodium hydroxide solution into the first reaction solution, and adjusting the pH value to obtain a second reaction solution; stirring the second reaction solution at 40 DEG C to obtain a third reaction solution; distilling the third reaction liquid, and removing the solvent to obtain a crude product; carrying out water washing treatment on the crude product; and drying the washed product to obtain the modified dibutyltin dilaurate product. The coconut oil acid is used for replacing lauric acid, the coconut oil is used as liquid feeding, the feeding method is more convenient, and dibutyl coconut oil acid is mixed fatty acid tin mainly containing dibutyltin dilaurate and is low in melting point and convenient to use in winter.

The invention discloses a modified palm oil polyol, a preparation method thereof and a polyurethane structural adhesive, and belongs to the field of polymer chemistry, the preparation method comprises the following steps: (1) performing saponification reaction on palm oil by using alkali liquor to obtain mixed fatty acid salt; (2) carrying out acidification reaction on the fatty acid salt crude product by utilizing acid liquor to obtain mixed fatty acid; (3) mixing the mixed fatty acid with micromolecular polyol for esterification reaction to obtain palm oil-based polyol ester; and (4) performing epoxidation reaction on the palm oil-based polyol ester to obtain the modified palm oil polyol, and the modified palm oil polyol obtained by the preparation method provided by the invention can endow the polyurethane structural adhesive with the advantages of low viscosity, low hardness and high bonding strength.

The invention belongs to the technical field of pentaerythritol fatty acid ester synthesis, and particularly relates to pentaerythritol mixed fatty acid ester as well as a preparation method and application thereof. The preparation method comprises the following steps: mixing pentaerythritol, fatty acid, a catalyst and a water-carrying agent, and carrying out esterification reaction to obtain esterification reaction liquid; carrying out purification treatment on the esterification reaction liquid to obtain pentaerythritol mixed fatty acid ester; the fatty acid comprises n-heptanoic acid, n-octanoic acid and 3, 5, 5-trimethyl hexanoic acid, and the molar ratio of the n-heptanoic acid to the n-octanoic acid to the 3, 5, 5-trimethyl hexanoic acid is (1-8): (1-8): 2. According to the invention, acid raw materials for esterification reaction are reasonably selected to react with pentaerythritol, and meanwhile, the molar ratio of three fatty acids is regulated and controlled, so that the obtained pentaerythritol mixed fatty acid ester has the characteristics of low viscosity and high ignition point, thereby having excellent low-temperature fluidity and high-temperature stability; meanwhile, the pentaerythritol mixed fatty acid ester provided by the invention also has excellent electrical performance.

The invention discloses a paederia scandens suppository and a preparation method thereof. The paederia scandens suppository comprises the following raw materials in parts by weight: 4-5 parts of mixed fatty glyceride and 1 part of paederia scandens powder, the preparation method specifically comprises the following steps: (1) weighing the raw materials; uniformly mixing the mixed fatty glyceride and the paederia scandens powder, and stirring in a water bath until the mixture is molten; and (3) pouring into a suppository mold coated with glycerol in advance, oscillating, wiping off the overflowed mixed solution, freezing, and taking out to obtain the suppository. The suppository is prepared from the mixed fatty glyceride and the paederia scandens powder, is administrated through an anal plug, has the effects of clearing away heat and toxic materials, eliminating dampness, relieving swelling and pain, stopping bleeding and the like, has the modern medical effects of resisting inflammation, easing pain and the like, is homologous in medicine and food and is non-toxic, so that the purpose of effectively treating mixed hemorrhoids is achieved; the composition has the advantages of unique formula, low cost, safety, reliability, remarkable curative effect and the like.

The invention provides a coating method and application of a hydroxy fatty acid-containing compound fertilizer. Comprising the following steps: preparing a solution from a mixture of medium-chain potassium 3-hydroxyaliphatate, long-chain potassium aliphatate and sodium alginate, and spraying the solution on the surfaces of compound fertilizer particles to form a pre-coating layer; then spraying a metal salt solution containing CaCl2 or MgCl2, reacting and drying under the condition of 40-60 DEG C, so that the mixed potassium aliphatate is converted into Ca / Mg metal soap in situ on the surfaces of the particles, thereby forming a hydrophobic metal soap film layer. The obtained film layer is insoluble in the initial stage, is resistant to water corrosion and can effectively delay dissolution of nutritional ingredients in the compound fertilizer; after application, the metal soap film is exposed in a microorganism or CO2 environment, and the metal soap film is gradually degraded, so that the controlled release of the fertilizer and the coating film layer is realized. The method is convenient to use and suitable for large-scale production of the compound fertilizer. Medium-chain 3-hydroxy fatty acid has a unique effect of promoting growth of underground rhizomes, and the fatty acid metal soap coated compound fertilizer can be used for promoting growth of underground rhizome crops so as to achieve the purpose of increasing production and income.

This invention discloses a trimethylolpropane mixed fatty acid ester, its preparation method, and its applications. The mixed fatty acid ester is obtained by esterification of two or more fatty acids with trimethylolpropane. The fatty acids are selected from combinations of octanoic acid, decanoic acid, and oleic acid, or combinations of oleic acid with octanoic acid or decanoic acid. The mixed fatty acid ester of this invention possesses both a high flash point and a low pour point, while maintaining low viscosity at low temperatures. It also exhibits excellent dielectric properties, meeting the various requirements of electrical equipment for insulating media. Furthermore, this mixed fatty acid ester uses renewable fatty acids as raw materials, has good biodegradability, aligns with the trend of green and environmentally friendly development, and avoids the environmental pollution problems caused by traditional mineral insulating oils and some synthetic insulating oils. It has broad application prospects in power equipment such as transformers and capacitors.

The invention belongs to the technical field of mineral flotation, and particularly relates to preparation of a bastnaesite collecting agent, which comprises the following steps: mixing and uniformly stirring mixed fatty acid ester, an oximation reagent, a solvent and a surfactant, adding an acid-binding agent in batches, controlling the reaction temperature to be lower than 40 DEG C, heating after the addition of the acid-binding agent is finished, reacting for 2-8 hours at the temperature below 70 DEG C, and filtering to obtain the bastnaesite collecting agent. And after the solvent is removed, the bastnaesite collecting agent is obtained. The bastnaesite collecting agent is applied to flotation of bastnaesite, and the grade and the recovery rate of the bastnaesite can be remarkably improved through the flotation process of one-time roughing, one-time scavenging and three-time concentration.

The application discloses a textile auxiliary composition, comprising: 60-90% of mixed fatty acid glyceride and the balance of mixed non-ionic surfactant, wherein the mixed fatty acid glyceride comprises a mixture of triglyceride, polyglycerol triglyceride, mixed fatty acid and polyglycerol; and the mixed non-ionic surfactant comprises fatty alcohol alkoxylate, fatty acid alkoxylate, glycerol monostearate and the like. The mixed fatty acid glyceride is first put into a reaction kettle, the reaction kettle is heated to 70 DEG C, and the mixed fatty acid glyceride is melted; the fatty acid alkoxylate, the glycerol monostearate and the fatty alcohol alkoxylate are weighed in the reaction kettle in sequence, constant temperature stirring and emulsification are carried out, and the product is obtained; then the product is transferred to a granulation packaging line, weighed, packaged and stored, and the textile auxiliary composition is obtained. The application can effectively solve the problem of oil and fat chemical waste, convert low-value by-products into high-value products, realize waste recycling and sustainable production of oil and fat chemicals.

The application provides a preparation method of medium-chain triglyceride, related products and application, and relates to the technical field of oil manufacturing. The preparation method comprises the following steps: mixing anhydrous calcium hydrogen phosphate, hydroxyapatite, carboxymethyl chitosan, Candida rugosa lipase and water, stirring, ultrasonic treatment, centrifugation, and obtaining immobilized lipase; then, the immobilized lipase is used for enzymolysis reaction with coconut oil and / or palm kernel oil to obtain mixed fatty acids; and then, catalyzing esterification reaction between the mixed fatty acids and glycerol to obtain medium-chain triglyceride. Through adjusting the types and proportions of the components in the immobilized lipase, the hydrolysis selectivity of the lipase to medium-chain fatty acids is improved, and then the yield of the medium-chain triglyceride is improved.

The present invention discloses a basil volatile oil vaginal suppository, a preparation method, and an application thereof. The suppository is composed of a mixture of a water-soluble matrix, an oily matrix, basil volatile oil, and an emulsifier. The water-soluble matrix comprises distilled water, polyethylene glycol 4000, and polyethylene glycol 6000, and the oily matrix comprises mixed fatty acid glycerides (stearin). The ratio of the water-soluble matrix to the oily matrix is ​​8:8-10. The basil volatile oil vaginal suppository of the present invention has moderate hardness, is not easily deformed, has good plasticity and stability, and has a moderate dissolution time and good solubility. This prevents the drug from dissolving too quickly or too slowly in the human body, ensuring that the drug is absorbed in the body to achieve the desired effect. It can stably release the drug in the vagina while reducing irritation to the vaginal mucosa. It has a precise therapeutic effect and low side effects in the treatment of vaginitis caused by Candida albicans.