525 results about "Saturated fatty acid" patented technology

The invention discloses a schizochytrium limacinum genetic engineering strain capable of remodeling an FAS (Fibroblast Activated Sequence) pathway as well as a construction method and application thereof. The schizochytrium limacinum gene engineering strain is obtained by heterologous expression of a C16 elongase gene E16, a C18 elongase gene E18, a delta 9 desaturase gene D9, a delta 5 desaturase gene D5, a delta 6 desaturase gene D6 and a delta 15 desaturase gene D15 in a schizochytrium limacinum wild type. The recombinant schizochytrium limacinum described herein is capable of producing EPA comprising 2.08% by total fatty acids while also producing DHA comprising at least more than 41% by total fatty acids. In addition, the invention discloses a method for producing unsaturated fatty acid through a double-path channel of PKS and FAS, which is beneficial to promotion and application of a technology for producing EPA and DHA by schizochytrium limacinum.

The invention relates to a laundry gel bead with excellent stability. The laundry gel bead with excellent stability comprises the following components: a surfactant, a modified surfactant, a solvent, a neutralizer, a chelating agent and an auxiliary agent, wherein the modified surfactant is obtained by reacting acrylic acid modified fatty alcohol-polyoxyethylene ether, sodium p-styrenesulfonate and methyl oleate ethoxylate. As the modified surfactant contains a large amount of ethyoxyl and other groups, the modified surfactant can act together with other ethyoxyl-containing surfactants to balance the irritation caused by a large amount of sulfonic acid, saturated fatty acid and other components in the laundry gel bead formula, thereby enhancing the mildness of the laundry gel beads, lowering the irritation of the washed clothes residues, and enhancing the laundry gel bead mildness. The irritation to skin and clothing fibers is effectively reduced; in addition, the modified surface active agent, the anionic surface active agent and the nonionic surface active agent act together, so that the dirt-removing capability of the laundry condensate beads is improved together.

The invention discloses a eutectic composite phase change material and a preparation method thereof, the composite phase change material takes long-chain fatty acid, long-chain alcohol and saturated fatty acid as raw materials, and the obtained composite phase change material shows excellent heat storage and release capability and temperature regulation capability.

The invention provides a method for preparing diglyceride oil by a solventless enzymatic method, which comprises the following steps: S1, mixing saturated fatty acid A and saturated fatty acid B to prepare a liquid eutectic mixture; s2, mixing the eutectic mixture, glycerol and lipase in a reaction system, and carrying out esterification reaction to obtain diglyceride; s3, separating the prepared diglyceride, adding the saturated fatty acid A and / or the saturated fatty acid B into the reaction system again to form a liquid eutectic mixture again, and repeating the step 2; wherein in the step S1, the saturated fatty acid A and the saturated fatty acid B are selected from C10-C20 alkanoic acid, in the step S2, the mass ratio of the eutectic mixture to the glycerol is 1: (1-5), and the temperature of the esterification reaction is 35-78 DEG C. The method solves the problem that the high-melting-point saturated fatty acid is difficult to utilize in the existing technology for preparing the diglyceride oil by the solvent-free enzymatic method.

The invention relates to the technical field of microbiology and food processing, in particular to pediococcus acidilactici and application of the pediococcus acidilactici in preparation of a brain-intestinal axis regulating efficacy metagen product.The high-activity pediococcus acidilactici DY-1 is separated out from natural fermentation pickles of super-polyselenium plant cardamine violifolia for the first time; the strain can be widely applied to fermentation of high-selenium plant-based food, can significantly promote glycolysis release of selenium-containing active substances, has good acid resistance, high protease activity and high lipase activity, can fully ferment plant-based fermentation raw materials, and has high yield. Glycolysis of macromolecular substances such as protein, saccharides and fat is facilitated, accumulation of active ingredients such as essential amino acid, unsaturated fatty acid, alkaloid and phenolic substances is promoted, and the edibility and functionality of the product are improved; and the organic selenium-rich metagen product prepared by sterilizing the fermentation mixture can synergistically improve human body cognition and emotion regulation regulated by microorganism-intestinal-brain axis.

An object of the present invention is to provide a lactase solution showing good permeation through a filtration filter, a lactase solution showing good permeation through a filtration filter and having a good residual lactase activity, and a lactase solution showing good permeation through a filtration filter and having a good residual lactase activity even when a lactase solution having a low protease activity and a low arylsulfatase activity as contaminant enzymes is used.A lactase solution containing any of (i) to (iii) below.(i) 0.0001 to 0.1 mass % of an unsaturated fatty acid or a salt thereof(ii) 0.0001 to 0.1 mass % of a saturated fatty acid salt(iii) 0.01 to 10 mass % of at least one selected from yeast extract, soybean peptone, pea protein, a casein degradation product, and corn steep liquor

Provided is an insulin secretion-promoting agent comprising, as an active ingredient, a triglyceride represented by the following formula (I):wherein R1, R2 and R3 each denotes a saturated fatty acid residue, at least one of which is a pentadecanoic acid residue. An insulin secretion-promoting action of the pentadecanoic acid triglyceride at the time of elevated blood glucose level is discovered, and pharmaceuticals and health foods for improving blood glucose level and diabetes are provided using this triglyceride.

The invention provides a negative electrode piece, a battery, an energy storage device and electric equipment, the negative electrode piece comprises a negative electrode current collector, at least one surface of the negative electrode current collector is provided with a negative electrode material layer, and the negative electrode material layer comprises a negative electrode material and a negative electrode binder; the negative electrode binder comprises modified styrene-butadiene rubber particles formed by a styrene-butadiene rubber main chain, long-chain unsaturated fatty acid with the carbon chain length of C14-C24 and an anhydride compound; the average particle size of the modified styrene butadiene rubber particles is D50, and D50 is larger than or equal to 190 nm and smaller than or equal to 210 nm.

The present application relates to the field of biochemical engineering, and discloses a composition containing eicosapentaenoic acid ethyl ester, a preparation method therefor, and a use thereof. The preparation method for the composition containing eicosapentaenoic acid ethyl ester disclosed in the present application comprises the following steps: transesterification, multi-stage molecular distillation, urea inclusion, rectification and preparative chromatographic purification. In the present application, by means of performing molecular distillation and urea inclusion before rectification, a liquid mixture can be separated, removing high-boiling-point saturated fatty acid ethyl esters and most fatty acid ethyl esters with one double bond, thereby effectively lowering the rectification temperature and preventing the formation of excessive isomers. Furthermore, the composition obtained by means of the described steps can achieve an eicosapentaenoic acid ethyl ester content of as high as 96.5 area% to 99.5 area%, with low isomer and impurity content, making it suitable for use in the preparation of food and pharmaceuticals.

The invention provides an unsaturated fatty acid modified bio-based nano-composite coated fertilizer and a preparation method thereof, and belongs to the technical field of coated controlled-release fertilizers. The preparation method comprises the following steps: firstly, preparing a silicon-based fatty acid modified halloysite nanotube by taking unsaturated fatty acid, organosiloxane and a halloysite nanotube as raw materials, and preparing semi-cured degradable bio-based polyurethane by taking bio-based polyol, polyester diol and isocyanate as raw materials; the unsaturated fatty acid modified bio-based nano-composite coating material is prepared by modifying halloysite nanotubes, then loading the modified halloysite nanotubes onto the surface of the semi-cured degradable bio-based polyurethane, and heating and curing to obtain the unsaturated fatty acid modified bio-based nano-composite coating material, the coating material has excellent compactness and surface super-hydrophobicity, and the coated fertilizer obtained by compounding the coating material with the fertilizer has excellent controlled release performance.

The invention discloses a method for preparing chocolate with high heat resistance, blooming resistance, high dietary fiber and low saturated fatty acid based on biphase gel and a product, and belongs to the technical field of oil processing application, and the method comprises the following steps: adding an emulsifier and solid fat into edible vegetable oil, and heating and stirring until the emulsifier and the solid fat are completely molten to obtain an oil gel phase; adding dietary fibers into water, and completely dissolving the dietary fibers to form a hydrogel phase; and mixing the obtained hydrogel phase and the oil gel phase, carrying out high-speed shearing emulsification, and cooling to room temperature in an ice-water bath to obtain the biphase gel. Different types of biphase gels are prepared by adjusting the ratio of the oil phase to the water phase, and the biphase gels are used for partially replacing cocoa butter to prepare the chocolate, so that the fat content is reduced, the heat resistance of the chocolate is improved, the frosting phenomenon of the chocolate is effectively delayed, the prepared chocolate does not contain trans-fatty acids, the saturated fatty acids are reduced, and the chocolate has good stability. And dietary fibers are contained, so that human health is benefited.

The invention belongs to the technical field of shortening preparation, and particularly relates to shortening base oil with low calorie and high oxidation stability and a preparation method of the shortening base oil. According to the preparation method of the shortening base oil with low calorie and high oxidation stability, provided by the invention, the novel shortening base oil with high oxidation stability, zero trans form, low cholesterol and low calorie is produced by taking palm stearin, cyperus esculentus oil and medium-carbon-chain triacylglycerol oil as raw materials and taking immobilized lipase Lipozyme RMIM as a catalyst; the problems that existing shortening is poor in oxidation stability, high in cholesterol content, excessive in trans-fatty acid content and high in long-carbon-chain saturated fatty acid content can be solved, and the low-calorie high-nutrition high-quality shortening has extremely wide application prospects in the field of preparation of low-calorie high-nutrition high-quality shortening.

Provided is a collagen production promoter comprising, as an active ingredient, a triglyceride represented by the following formula (I), wherein R1, R2 and R3 each denotes a saturated fatty acid residue, at least one of which is a pentadecanoic acid residue. The triglyceride comprising the pentadecanoic acid promotes the production of skin fibroblasts and collagen, and can be used as a topical skin care composition and a beauty food or beverage for improving the condition of skin.

The invention provides a hydrophobic modified chitosan material as well as a preparation method and application thereof in wound care and hemostasis. The hydrophobic modified chitosan material provided by the invention comprises chitosan and saturated fatty acid physically crosslinked on a side chain of the chitosan, the deacetylation degree of the chitosan is 75 to 95 percent; the carbon chain length of the saturated fatty acid is 11-18 carbon atoms. The hydrophobic modified chitosan material provided by the invention can be used for stopping arterial bleeding.

The invention relates to the technical field of preparation methods of nutritional products, in particular to a preparation method of ganoderma lucidum spore oil with a liver regulating effect. Comprising the steps of preparing ganoderma lucidum spore powder, extracting ganoderma lucidum spore oil and enriching the ganoderma lucidum spore oil. Ganoderma lucidum blocks are treated through an ultrasonic extraction technology, ganoderma lucidum spore powder is prepared through a spray drying method, n-hexyl alcohol is used for soaking extraction, high-purity ganoderma lucidum spore oil is obtained through vacuum concentration and molecular distillation, and residual solvent is removed through film evaporation. Active ingredients such as triterpenoids and unsaturated fatty acid are further enriched by using supercritical CO2 extraction; the extraction efficiency and the purity of active ingredients of the ganoderma lucidum spore oil are remarkably improved, the obtained ganoderma lucidum spore oil has remarkable effects in the aspects of reducing liver toxicity indexes (ALT and AST) and enhancing antioxidant enzyme activity (SOD and GSH-Px), the operation controllability is high, the ganoderma lucidum spore oil is suitable for large-scale industrial application, and technical support is provided for research and development of liver protection drugs and functional food.

The invention provides vitamin B12 modified microspheres capable of efficiently loading His tag recombinant protein as well as a preparation method and application of the vitamin B12 modified microspheres, and belongs to the technical field of biological medicines. The preparation method of the vitamin B12 modified microsphere for efficiently loading the His tag recombinant protein comprises the following steps: (1) carrying out esterification reaction on unsaturated fatty acid containing sulfydryl, disulfide bond or olefinic bond, saturated fatty acid and vitamin B12 to prepare an amphiphilic vitamin B12-lipid conjugate; and (2) taking the amphiphilic vitamin B12-lipid conjugate, PLGA (poly (lactic-co-glycolic acid)), a multi-sulfydryl cross-linking agent and a photoinitiator as raw materials, and preparing the raw materials into microspheres by adopting a microfluidic method, so as to obtain the vitamin B12 modified microspheres capable of efficiently loading various His tag recombinant proteins. The microsphere provided by the invention overcomes the problems of protein load stability and burst release of traditional microspheres, and various different His tag recombinant growth factors can be flexibly selected according to the requirements on different growth factors in treatment of complex bone defects caused by different pathogenesis.

The invention relates to the technical field of lubricants, in particular to rolling oil for aluminum material hot rolling and a preparation method of the rolling oil, the rolling oil comprises 75 wt%-80 wt% of base oil, 15 wt%-20 wt% of unsaturated fatty acid, 2 wt%-3 wt% of ethanolamine compounds, 0.5 wt%-1 wt% of antioxidants, 0.5 wt%-1 wt% of boric acid, 0 wt%-0.5 wt% of defoaming agents and the balance inevitable impurities; according to the preparation method of the rolling oil, the raw materials react in the preparation process to synthesize effective components with the functions of an emulsifier, an extreme pressure anti-wear agent and the like, so that the effect of combining multiple raw materials can be achieved without special multiple kinds of raw materials, the lubricating and annealing detergency is good, the boric acid can inhibit dissolution of ethanolamine, and the service life of the rolling oil is prolonged. The service life of the rolling oil is prolonged.

The present invention relates to a lipid pre-concentrate and a method for preparing same, wherein the lipid pre-concentrate uses a biodegradable lipid having low injection force and low toxicity to delay the release rate of a drug, thereby exhibiting sustained release so that the administered drug can be continuously released for a long period of time.

The invention discloses a plant lactobacillus and application thereof, and belongs to the technical field of microorganisms. The plant lactobacillus 002P provided by the invention is a new strain, and is round, white, neat in edge, smooth in surface and soft in texture on an MRS solid culture medium; growth of bacteria can be remarkably inhibited, an inhibition effect on staphylococcus aureus, pseudomonas aeruginosa and escherichia coli is achieved, and the inhibition zone is 23.33-279.33 mm; the healing of infected wounds can be obviously promoted; the selenium conversion rate is excellent, and the maximum selenium conversion rate can reach 88%; the nano-selenium prepared from the plant lactobacillus 002P is spherical, has the particle size of 200-500nm, has excellent properties of resisting oxidation, relieving hepatotoxicity induced by saturated fatty acid, promoting expression of selenoprotein in a mouse body and reducing blood fat, and has a wide application prospect.

The application discloses a preparation method of a high internal phase emulsion stabilized only by proteins, which mixes a completely hydrated protein solution as a water phase with an oil phase, and controls the hydrodynamic characteristics of a shearing emulsification process to obtain the high internal phase emulsion stabilized only by proteins. The preparation method of the application can obtain the high internal phase emulsion stabilized only by food-grade proteins through one-step shearing emulsification without other measures. The prepared high internal phase emulsion has good gel characteristics, stability and high safety, and can be used as a substitute for partially hydrogenated vegetable oil and saturated fatty acids. Meanwhile, the method is simple in operation, low in preparation cost and suitable for large-scale industrial promotion.

Provided is a composition for visual field defect disorders, glaucoma, light-induced ocular tissue damage and related disorders, which can be used as a food or drug for long-term administration, prevention, symptom relief and improvement. A composition comprising a triglyceride represented by the formula (I):(wherein R1, R2, and R3 are each a saturated fatty acid residue, and at least one of them is a pentadecanoic acid residue) as an active ingredient.

The application discloses application of 5,8,11-eicosatrienoic acid in prevention and treatment of plant fungal diseases and belongs to the field of pesticide chemistry. The 5,8,11-eicosatrienoic acid mainly prevents and treats diseases caused by the oomycete class capsicum phytophthora, the compound is a long-chain unsaturated fatty acid, has an antifungal disease effect and can be used as a fungicide to prevent and treat plant diseases. The compound can effectively prevent pathogenic bacteria from invading plants by inhibiting mycelium growth, enhancing cell membrane permeability and interfering with the spore sac release process, and is further used for preventing and treating huge plant fungal diseases. Biological tests show that the compound has a significant concentration-dependent inhibitory effect on the mycelium growth of the capsicum phytophthora, and the half effective inhibitory concentration (EC50) is 60.2 µg / mL. At a concentration of 200 µg / mL, the inhibition rate is more than 83%, the 5,8,11-eicosatrienoic acid can effectively inhibit the release of the capsicum phytophthora spore sac, and the EC50 is 156.3 µg / mL. At a concentration of 200 µg / mL, the inhibition rate is morethan 77%.

This invention discloses a method for preparing high-quality bio-based 1,9-nonanediol, comprising the following steps: transesterification, precipitation, fatty acid methyl ester refining, ozone oxidation pyrolysis, solvent recovery, esterification, dimethyl azelaate refining, and hydrogenation to obtain high-quality bio-based 1,9-nonanediol. This invention achieves gradient and full-component utilization of vegetable oil raw materials: the oil-based portion of triglycerides is used to produce high-quality bio-based 1,9-nonanediol, while simultaneously producing byproducts such as methyl palmitate, methyl stearate, propionic acid, hexanoic acid, and nonanoic acid; the glycerol-based portion of triglycerides is used as a byproduct of glycerol production. This invention utilizes esterification to reconstruct the products of ozone oxidation pyrolysis, converting the high-boiling-point monomethyl azelaate into the low-boiling-point dimethyl azelaate, achieving efficient separation from saturated fatty acid methyl esters. The dimethyl azelaate, as a raw material, is then hydrogenated to obtain high-quality nonanediol, significantly reducing production costs.

Provided is a small-piece oil and fat composition having good dispersibility and extensibility. This small-piece oil and fat composition contains 65%-100% by mass of edible oil and fat, wherein: the content of a saturated fatty acid having 16 carbon atoms in fatty acids constituting the edible oil and fat is 35%-60% by mass; the content of a saturated fatty acid having 18 carbon atoms in the fatty acids constituting the edible oil and fat is 3%-20% by mass; and the solid fat content of the edible oil and fat at 20°C is 39%-50%.

A wet-state indicator composition is provided, which is excellent in color change performance and in which odor is suppressed. Disclosed is a wet-state indicator composition comprising: a hydrocarbon oil (A); at least one selected from saturated fatty acids having 16 or more carbon atoms and derivatives of the saturated fatty acids (B); and a moisture-sensitive colorant composition (C), wherein component (B) is contained in an amount of 2 to 85 parts by mass based on 100 parts by mass of the total amount of components (A) to (C).

The invention relates to a method for fermenting fermented soya beans by rosa roxburghii tratt fruits, soybeans and black beans. The fermentation comprises the following steps: pretreating raw materials, fermenting to prepare fermented soya bean koji, post-fermenting and drying. 3-5 wt% of roxburgh rose juice and 3-5 wt% of roxburgh rose pulp residues are added in the post-fermentation step, the roxburgh rose pulp residues can enrich the taste of the fermented soya bean finished product, roxburgh roses contain rich vitamin C and polyphenol substances and are natural antioxidants, and bad flavor generated by oxidative rancidity of fatty acid in the post-fermentation and storage process of the fermented soya beans is prevented; meanwhile, the soybeans are rich in unsaturated fatty acid, the healthy lipid components are protected from being damaged through the antioxidant effect of the roxburgh rose, the retained unsaturated fatty acid can serve as a precursor to help saccharomycetes to generate more ester aroma substances, the antioxidant effect of the roxburgh rose and microorganisms in the fermented soya beans achieve the synergistic effect, and the effect of improving the immunity of the fermented soya beans is achieved. The flavor is indirectly enhanced, the original taste is not influenced, and the stability and the nutritional value of the fermented soya beans are also improved.

The present disclosure provides methods and compositions comprising hyaluronic acid (HA) hydrogel in combination with a saturated fatty acid for treating osteoarthritis. In some embodiments, aspects of the disclosure relate to pharmaceutical compositions comprising HA hydrogel in combination with a steroid. In some embodiments, the pharmaceutical compositions may be administrable via local, topical, and injection. In some embodiments, the pharmaceutical composition may be administrable by intra-articular injection.

Triphenylphosphonium hydroxytyrosol TPP-HT, its synthesis method and application in the preparation of drugs for improving aortic endothelial cell function. TPP-HT can significantly increase the reduction of human aortic endothelial cell activity caused by saturated fatty acids, inhibit the inflammatory response and oxidative stress caused by saturated fatty acids, and at the same time increase the synthesis of ATP in vascular endothelial cells and the expression of mitochondrial complex II. By anti-inflammatory and protecting mitochondrial function, it can prevent the occurrence and development of atherosclerosis. Therefore, TPP-HT has good application prospects in preventing cardiovascular diseases such as atherosclerosis caused by high-fat-induced endothelial damage, opening up a new medical approach for preventing a series of problems of cardiovascular diseases such as atherosclerosis caused by endothelial damage due to unbalanced dietary structure, and providing a new basis for the development of new drugs.

The invention discloses a medicine manufacturing technological process, relates to the technical field of pharmacy, and solves the technical problem that long-chain unsaturated fatty acid cannot be effectively removed in an existing technical scheme. The medicine manufacturing technological process comprises badger skin and comprises the steps that 1, badger skin fat is minced and mixed with water and sodium chloride to be heated, moisture is evaporated, and a mixture is obtained; a mixture containing badger fat and fat residues is obtained; 2, carrying out solid-liquid separation on the mixture obtained in the step 1 to obtain crude badger fat and fat residues; step 3, mixing the crude badger fat obtained in the step 2 with water, heating to boiling, then cooling, and obtaining an oleic acid intermediate by utilizing an oil-water separation technology; a pure physical method of low-temperature fractional crystallization and high-speed centrifugal separation is adopted to replace a traditional chemical alkali refining method, introduction of any chemical reagent in the production process is avoided, the risk of chemical residues is fundamentally eradicated, and the pure natural property and safety of a final product are guaranteed.

The present application relates to an antifungal microneedle patch and its preparation method and application, the antifungal microneedle patch includes backing layer and the needle head arranged on the surface of the backing layer;The needle head constitutes n×n array on the surface of the backing layer;The surface of the needle head includes fatty acid coating containing antibacterial drug;The inside of the needle head includes photosensitizer;The n is selected from integer.The antibacterial drug is lipophilic triazole antifungal drug.The fatty acid is selected from saturated fatty acid containing 6-12 carbon atoms.The present application innovatively combines antifungal drug itraconazole and photo-thermal agent / photosensitizer indocyanine green, loads in microneedle, can carry out painless minimally invasive local administration, through the antibacterial action, photo-thermal effect and photodynamic effect of antifungal drug released under the excitation of near-infrared light, realize the effective killing to fungi, and will not cause irreversible damage to normal tissue.