222 results about "Saturated fatty acid" patented technology

Provided is a collagen production promoter comprising, as an active ingredient, a triglyceride represented by the following formula (I), wherein R1, R2 and R3 each denotes a saturated fatty acid residue, at least one of which is a pentadecanoic acid residue. The triglyceride comprising the pentadecanoic acid promotes the production of skin fibroblasts and collagen, and can be used as a topical skin care composition and a beauty food or beverage for improving the condition of skin.

The invention provides vitamin B12 modified microspheres capable of efficiently loading His tag recombinant protein as well as a preparation method and application of the vitamin B12 modified microspheres, and belongs to the technical field of biological medicines. The preparation method of the vitamin B12 modified microsphere for efficiently loading the His tag recombinant protein comprises the following steps: (1) carrying out esterification reaction on unsaturated fatty acid containing sulfydryl, disulfide bond or olefinic bond, saturated fatty acid and vitamin B12 to prepare an amphiphilic vitamin B12-lipid conjugate; and (2) taking the amphiphilic vitamin B12-lipid conjugate, PLGA (poly (lactic-co-glycolic acid)), a multi-sulfydryl cross-linking agent and a photoinitiator as raw materials, and preparing the raw materials into microspheres by adopting a microfluidic method, so as to obtain the vitamin B12 modified microspheres capable of efficiently loading various His tag recombinant proteins. The microsphere provided by the invention overcomes the problems of protein load stability and burst release of traditional microspheres, and various different His tag recombinant growth factors can be flexibly selected according to the requirements on different growth factors in treatment of complex bone defects caused by different pathogenesis.

The application discloses a preparation method of a high internal phase emulsion stabilized only by proteins, which mixes a completely hydrated protein solution as a water phase with an oil phase, and controls the hydrodynamic characteristics of a shearing emulsification process to obtain the high internal phase emulsion stabilized only by proteins. The preparation method of the application can obtain the high internal phase emulsion stabilized only by food-grade proteins through one-step shearing emulsification without other measures. The prepared high internal phase emulsion has good gel characteristics, stability and high safety, and can be used as a substitute for partially hydrogenated vegetable oil and saturated fatty acids. Meanwhile, the method is simple in operation, low in preparation cost and suitable for large-scale industrial promotion.

Provided is a composition for visual field defect disorders, glaucoma, light-induced ocular tissue damage and related disorders, which can be used as a food or drug for long-term administration, prevention, symptom relief and improvement. A composition comprising a triglyceride represented by the formula (I):(wherein R1, R2, and R3 are each a saturated fatty acid residue, and at least one of them is a pentadecanoic acid residue) as an active ingredient.

The application discloses application of 5,8,11-eicosatrienoic acid in prevention and treatment of plant fungal diseases and belongs to the field of pesticide chemistry. The 5,8,11-eicosatrienoic acid mainly prevents and treats diseases caused by the oomycete class capsicum phytophthora, the compound is a long-chain unsaturated fatty acid, has an antifungal disease effect and can be used as a fungicide to prevent and treat plant diseases. The compound can effectively prevent pathogenic bacteria from invading plants by inhibiting mycelium growth, enhancing cell membrane permeability and interfering with the spore sac release process, and is further used for preventing and treating huge plant fungal diseases. Biological tests show that the compound has a significant concentration-dependent inhibitory effect on the mycelium growth of the capsicum phytophthora, and the half effective inhibitory concentration (EC50) is 60.2 µg / mL. At a concentration of 200 µg / mL, the inhibition rate is more than 83%, the 5,8,11-eicosatrienoic acid can effectively inhibit the release of the capsicum phytophthora spore sac, and the EC50 is 156.3 µg / mL. At a concentration of 200 µg / mL, the inhibition rate is morethan 77%.

This invention discloses a method for preparing high-quality bio-based 1,9-nonanediol, comprising the following steps: transesterification, precipitation, fatty acid methyl ester refining, ozone oxidation pyrolysis, solvent recovery, esterification, dimethyl azelaate refining, and hydrogenation to obtain high-quality bio-based 1,9-nonanediol. This invention achieves gradient and full-component utilization of vegetable oil raw materials: the oil-based portion of triglycerides is used to produce high-quality bio-based 1,9-nonanediol, while simultaneously producing byproducts such as methyl palmitate, methyl stearate, propionic acid, hexanoic acid, and nonanoic acid; the glycerol-based portion of triglycerides is used as a byproduct of glycerol production. This invention utilizes esterification to reconstruct the products of ozone oxidation pyrolysis, converting the high-boiling-point monomethyl azelaate into the low-boiling-point dimethyl azelaate, achieving efficient separation from saturated fatty acid methyl esters. The dimethyl azelaate, as a raw material, is then hydrogenated to obtain high-quality nonanediol, significantly reducing production costs.

A wet-state indicator composition is provided, which is excellent in color change performance and in which odor is suppressed. Disclosed is a wet-state indicator composition comprising: a hydrocarbon oil (A); at least one selected from saturated fatty acids having 16 or more carbon atoms and derivatives of the saturated fatty acids (B); and a moisture-sensitive colorant composition (C), wherein component (B) is contained in an amount of 2 to 85 parts by mass based on 100 parts by mass of the total amount of components (A) to (C).

The invention relates to a method for fermenting fermented soya beans by rosa roxburghii tratt fruits, soybeans and black beans. The fermentation comprises the following steps: pretreating raw materials, fermenting to prepare fermented soya bean koji, post-fermenting and drying. 3-5 wt% of roxburgh rose juice and 3-5 wt% of roxburgh rose pulp residues are added in the post-fermentation step, the roxburgh rose pulp residues can enrich the taste of the fermented soya bean finished product, roxburgh roses contain rich vitamin C and polyphenol substances and are natural antioxidants, and bad flavor generated by oxidative rancidity of fatty acid in the post-fermentation and storage process of the fermented soya beans is prevented; meanwhile, the soybeans are rich in unsaturated fatty acid, the healthy lipid components are protected from being damaged through the antioxidant effect of the roxburgh rose, the retained unsaturated fatty acid can serve as a precursor to help saccharomycetes to generate more ester aroma substances, the antioxidant effect of the roxburgh rose and microorganisms in the fermented soya beans achieve the synergistic effect, and the effect of improving the immunity of the fermented soya beans is achieved. The flavor is indirectly enhanced, the original taste is not influenced, and the stability and the nutritional value of the fermented soya beans are also improved.

The present disclosure provides methods and compositions comprising hyaluronic acid (HA) hydrogel in combination with a saturated fatty acid for treating osteoarthritis. In some embodiments, aspects of the disclosure relate to pharmaceutical compositions comprising HA hydrogel in combination with a steroid. In some embodiments, the pharmaceutical compositions may be administrable via local, topical, and injection. In some embodiments, the pharmaceutical composition may be administrable by intra-articular injection.

The invention discloses a medicine manufacturing technological process, relates to the technical field of pharmacy, and solves the technical problem that long-chain unsaturated fatty acid cannot be effectively removed in an existing technical scheme. The medicine manufacturing technological process comprises badger skin and comprises the steps that 1, badger skin fat is minced and mixed with water and sodium chloride to be heated, moisture is evaporated, and a mixture is obtained; a mixture containing badger fat and fat residues is obtained; 2, carrying out solid-liquid separation on the mixture obtained in the step 1 to obtain crude badger fat and fat residues; step 3, mixing the crude badger fat obtained in the step 2 with water, heating to boiling, then cooling, and obtaining an oleic acid intermediate by utilizing an oil-water separation technology; a pure physical method of low-temperature fractional crystallization and high-speed centrifugal separation is adopted to replace a traditional chemical alkali refining method, introduction of any chemical reagent in the production process is avoided, the risk of chemical residues is fundamentally eradicated, and the pure natural property and safety of a final product are guaranteed.

The present application relates to an antifungal microneedle patch and its preparation method and application, the antifungal microneedle patch includes backing layer and the needle head arranged on the surface of the backing layer;The needle head constitutes n×n array on the surface of the backing layer;The surface of the needle head includes fatty acid coating containing antibacterial drug;The inside of the needle head includes photosensitizer;The n is selected from integer.The antibacterial drug is lipophilic triazole antifungal drug.The fatty acid is selected from saturated fatty acid containing 6-12 carbon atoms.The present application innovatively combines antifungal drug itraconazole and photo-thermal agent / photosensitizer indocyanine green, loads in microneedle, can carry out painless minimally invasive local administration, through the antibacterial action, photo-thermal effect and photodynamic effect of antifungal drug released under the excitation of near-infrared light, realize the effective killing to fungi, and will not cause irreversible damage to normal tissue.

The invention discloses a preparation method of pure plant-based fat-reducing pattern-mounting single cream, which is characterized in that plant protein is modified through a double-enzyme synergistic effect of protein endonuclease and protein-glutaminase, and the plastic range of plant oil in a refrigeration environment is regulated and controlled by controlling the ratio of saturated fatty acid to unsaturated fatty acid; the special vegetable protein and the plastic grease are formed. The two components are core ingredients for preparing the pure plant-based single cream, the fat content can be controlled within 15%, the fat content is reduced by 20% compared with that of traditional single cream, and meanwhile the product still has excellent whipping performance and pattern mounting forming capacity. According to the product obtained by the method, fat reduction of high-fat food is realized, the original processing performance of the high-fat food is maintained, and the urgent demand of the market on healthy and functional single cream products can be met.

The present application relates to a kind of biodegradable hydraulic oil composition and its preparation method, it includes the following weight parts of component: biodegradable base oil 96.0-98.5 parts and composite detergent 1.5-2.5 parts;The base oil is the mixture of pentaerythritol tetraester and trimethylolpropane triester, fatty acid chain is C8-C10 saturated fatty acid, saturation ≥90%, 28 days biodegradability meets the determination of OECD 301B;The composite detergent includes: octylated diphenylamine 0.45-0.90 parts, 2,6-di-tert-butyl-4-methylphenol 0.10-0.25 parts, 2-ethylhexyl acidic phosphate and its ethanolamine salt 0.60-1.20 parts, dodecenyl succinic acid di (2-ethylhexyl ester) 0.15-0.35 parts, and the mass ratio of octylated diphenylamine and 2,6-di-tert-butyl-4-methylphenol is 1.5:1~4:1.

To provide a composition containing a novel ingredient that can bring about at least an acceptable level of sebum control in keratinous substances such as skin. [Solution] The present invention relates to a composition comprising (a) (i) at least one inorganic oxide, preferably a metal oxide, more preferably an alkaline earth metal oxide, and (ii) at least one fatty acid or a salt thereof, preferably a saturated fatty acid or a salt thereof, more preferably a metal salt of a saturated fatty acid, and (b) at least one second powder selected from particles containing silica and hydroxyapatite. The composition according to the present invention can provide at least an acceptable level of sebum control to keratinous substances such as skin.

The application discloses a kind of eluent and its preparation method and application, preparation method includes: adding potassium methoxide methanol solution to the trimethylolpropane in molten state, after stirring, vacuumizing, then droping glycidol monomer, after reaction, add methanol, dry, obtain hyperbranched polyglycerol ether;Add carbonyl imidazole to the N,N-dimethylformamide solution of saturated fatty acid, after stirring and mixing, drop to the N,N-dimethylformamide solution of hyperbranched polyglycerol ether, reaction is heated in nitrogen atmosphere, after reaction, the product is treated, obtain temperature-sensitive hyperbranched polyglycidol ether eluent.The eluent prepared in the application can greatly reduce the treatment cost of elution waste liquid while efficiently removing heavy metals.

The invention discloses a hotpot condiment as well as a preparation method and application thereof. Belongs to the technical field of food processing. Comprising the following steps: pretreating raw materials; performing low-temperature stir-frying and boiling; and cooling and molding. The ratio of grease is optimized, and medicinal and edible raw materials are introduced, so that saturated fatty acid and greasy feeling are remarkably reduced, the eating problem of high-fat crowds is solved, and the conversion to'mild health maintenance 'is realized. The product is excellent in thermal stability, free of muddy soup, bitter and greasy after being boiled for a long time, and gentle in spicy taste. The instant boiling blocky design is adopted, secondary stir-frying is avoided, and operation is convenient and standardized. The food therapy effects of nourishing the stomach, cleansing grease and the like are fused, and spicy stimulation is relieved. The technology is mature, the quality is consistent, the color is natural, the cost structure is optimized, and popularization of high-quality health-preserving hotpots is promoted.

A low-oil-loss plastic fat which is low in saturated fatty acids, and a low-temperature preparation method therefor. The method comprises: dispersing OSA starch in an aqueous solution and stirring, to obtain an OSA starch aqueous solution; dispersing chitosan in an acetic acid aqueous solution and stirring, to obtain a chitosan solution; mixing the obtained OSA starch aqueous solution with the chitosan solution, adjusting the pH to 5.5-6.5 and stirring, to obtain an OSA starch-chitosan electrostatic complex; mixing and stirring the obtained OSA starch-chitosan electrostatic complex with soybean oil, to obtain an oil-in-water emulsion, then drying until the water is removed, to obtain a solid lipid; subjecting the obtained solid lipid to high-speed shearing, to form an oil gel. The oil gel can be applied in the food field.

Disclosed is a vegetable fat composition comprising different triglycerides with at least some of the triglycerides comprising C14-fatty acids. The vegetable fat composition is for use in bakery, dairy, or confectionary applications or in chocolate or chocolate-like coating, as well as a method of producing said vegetable fat composition. A vegetable fat composition as disclosed has some of the properties from cocoa butter substitute and some of the properties from cocoa butter replacer, combined in one product, in addition to being a cost effective vegetable fat composition.

DEPCT64 A humectant containing oil and other components for external use on the skin. In addition, a specific characteristic of this invention is that it contains an esterification product. Component A and component B, or the esterification product containing component A and component B. And the components C and the esterification products have a pH value of 0-160. Milligrams of KOH / gram and the mass ratio of fatty acid residues obtained from component B and fatty acid residues. Fats obtained from component C in fatty acid residues which make up the esterification products. Elements A, B, and C are equal to 99.9:0.1-45:55 elements. A: Polyhydric alcohols that are dipentaerythritol, erythritol, or sorbitan; B: Components. One or more fatty acids, or equal to two, selected from straight-chain saturated fatty acids with a certain number of carbon atoms. 6-10 atoms, C composition: 1 or more fatty acids, or equal to 2 types selected from fatty acids. Containing 6-28 carbon atoms (excluding element B). -----------------------------------------------------------

The present invention relates to a fat composition comprising at least 30 wt% of stearic acid (C18:0) and at least 45 wt% of saturated fatty acids (SAFA); and wherein the fat composition comprises 1.0 to 8.0 wt% of SSS triglycerides and at most 10.0 wt% of UUU triglycerides, and the weight ratio of S2U triglycerides to SSS triglycerides of the fat composition is 6.0 to 20.0 and the weight ratio of S2O triglycerides to S2L triglycerides is at most 30.0; wherein S is a saturated fatty acid, U is an unsaturated fatty acid, O is oleic acid and L is linoleic acid. The present invention further relates to a fat blend comprising the fat composition as hard stock, wherein the fat blend is further used in a water-in-oil emulsion product, such as a margarine or a spread.

The invention provides new application of lauric acid, and researches on the inhibiting effect of lauric acid on a cardiac voltage gated sodium channel Nav1.5 and the action mode of lauric acid in electrophysiological conduction prove that natural polysaturated fatty acid lauric acid is a potential Nav1.5 sodium channel inhibitor for the first time. Electrophysiological characterization shows that lauric acid is the most effective monomer in natural polysaturated fatty acid screened for inhibiting Nav1.5, and the IC50 value is 27.40 + / -12.78 mu M.

This invention provides a carbon-coated lithium-rich manganese-based cathode material, its preparation method, and a lithium battery, belonging to the field of cathode material technology. This invention utilizes an unsaturated fatty acid solution mixed with a lithium-rich manganese-based cathode material and then evaporated to dryness. During the evaporation process, the unsaturated fatty acid adapts to and coats the lithium-rich manganese-based cathode material. Furthermore, the carbon chains of the unsaturated fatty acid can directly coat the surface of the lithium-rich manganese-based cathode material particles. Therefore, using unsaturated fatty acid as a carbon source can form a uniform and dense coating layer on the surface of the lithium-rich manganese-based cathode material. The mixed powder is sintered in an inert atmosphere to carbonize the unsaturated fatty acid coating layer. The reduction effect of carbon induces atomic rearrangement on the surface of the lithium-rich manganese-based cathode material, sequentially forming a dense spinel layer and a dense carbon coating layer on the surface of the lithium-rich manganese-based cathode material, thereby significantly improving the electrochemical performance of the carbon-coated lithium-rich manganese-based cathode material.

The invention discloses a composition for skin cleaning and application thereof, and belongs to the field of daily chemicals. The composition comprises glycolipid and a lauryl alcohol polyether carboxylic acid surfactant in a specific weight ratio. Wherein the glycolipid is preferably sophorolipid, and the lauryl alcohol polyether carboxylic acid surfactant is preferably lauryl alcohol polyether-5 carboxylic acid. According to the composition disclosed by the invention, the cleaning efficiency on unsaturated fatty acids (such as oleic acid and squalene) on the skin surface is remarkably improved on the premise of not excessively adding a high-effect anionic surfactant or sacrificing the product mildness. Meanwhile, the composition can effectively reduce degeneration damage to skin keratoprotein, has good skin mildness and safety, and is suitable for washing-off type personal care products for face cleaning, hair washing, bathing and the like.

The invention belongs to the field of anti-tumor compounds, and particularly relates to a preparation method of carboplatin-unsaturated fatty acid liposome, which comprises the following steps: S1, preparing lecithin into a lecithin solution; preparing unsaturated fatty acid into a fatty acid solution; preparing carboplatin into a carboplatin solution; s2, adding a lecithin solution and a fatty acid solution into an eggplant-shaped bottle, then adding chloroform or dichloromethane, uniformly mixing, and carrying out rotary evaporation to obtain a phospholipid membrane; s3, taking and preheating a carboplatin solution, adding the carboplatin solution into the phospholipid membrane after preheating, and performing ultrasonic hydration to obtain a liposome solution; s4, performing ultrasonic crushing on the liposome solution; and S5, filtering the ultrasonically crushed liposome solution to obtain the liposome. The invention also discloses an application of the carboplatin-unsaturated fatty acid liposome prepared by the preparation method in preparation of antitumor drugs. The problem that in the prior art, the curative effect and safety of a carboplatin drug are difficult to consider at the same time can be solved, and metastatic tumor cells can be effectively inhibited at low drug concentration.

The invention provides an asphalt cold-patch liquid and a preparation method thereof, and the asphalt cold-patch liquid comprises the following components in parts by mass: 100 parts of asphalt, 10-30 parts of resin containing unsaturated C = C double bonds, 20-50 parts of a long-chain unsaturated fatty acid compound and 1-2 parts of a photoinitiator, wherein the long-chain unsaturated fatty acid compound is selected from unsaturated fatty acid of which the carbon chain length is not less than C16 or ester derivatives thereof. The asphalt cold supplementing liquid abandons a traditional volatile solvent, emission of VOCs is eradicated fundamentally, and the asphalt cold supplementing liquid has excellent environment-friendly safety; long-chain unsaturated fatty acid contained in the asphalt can form a lubricating molecular film on the surfaces of asphalt particles, so that excellent flowability and construction convenience at normal temperature are guaranteed; unsaturated double bonds in the material can be subjected to rapid photopolymerization reaction under natural illumination to form a cross-linked network structure, so that intelligent curing from flowing state to high strength is realized. Through the mechanism, rapid forming can be achieved at the room temperature, the maintenance time is greatly shortened, and the maintenance efficiency is remarkably improved.

The invention belongs to the technical field of separation and purification, and particularly relates to a separation and purification system, application thereof and a method for separating and purifying saturated fatty acid amide. The separation and purification system provided by the invention comprises a spiral plate heat exchanger, a short-path molecular distiller, a horizontal distiller, a horizontal condenser, a vertical condenser and a product receiving tank which are communicated in sequence, a low-boiling-point substance outlet of the short-path molecular distiller is communicated with a front fraction receiving tank, the horizontal distiller is communicated with a falling film heater through a circulating pump, and a material outlet of the falling film heater is communicated with the horizontal distiller; and the top end of the vertical condenser is connected with a vacuum unit. The separation and purification system is simple and convenient to operate, can be suitable for separation and purification of various saturated fatty acid amides, and expands the application field. The product separated by the separation and purification system provided by the invention is high in purity (the amide content is greater than or equal to 98.5%), good in color (less than or equal to 100HaZen) and high in yield (greater than or equal to 95.5%).

Provided is a mixed powder for powder metallurgy that uses a fatty acid amide, which is a clean lubricant, and achieves excellent green compact ejectability and compressibility not only at room temperature but also after the die temperature has increased. A mixed powder for powder metallurgy comprises: an iron-based powder; and a fatty acid amide as a lubricant, wherein the fatty acid amide includes a saturated fatty acid bisamide, a saturated fatty acid monoamide, and an unsaturated fatty acid amide, the unsaturated fatty acid amide includes one or both of an unsaturated fatty acid bisamide and an unsaturated fatty acid monoamide, and the predetermined Formulas are satisfied.

To provide a composition for wet indicator which is excellent in discoloration performance and is suppressed in odor. What is disclosed is a composition for wet indicator comprising: a hydrocarbon oil (A), at least one selected from saturated fatty acids having 16 or more carbon atoms and derivatives thereof (B), and a wet-sensitive colorant composition (C), wherein the component (B) is contained in an amount of 2 to 85 parts by mass based on 100 parts by mass of the total amount of the components (A) to (C).

The application discloses a cream cheese and a preparation method and application thereof, and relates to the technical field of dairy products. The raw material of the cream cheese comprises light cream, the content of saturated fatty acids of the light cream is 69-72 wt%, the content of butyric acid in the light cream is 3-4 wt% based on total fatty acids, the content of myristic acid is 10-12 wt%, the content of palmitic acid is 32-35 wt%, the content of stearic acid is 8-11 wt%, and the ratio of palmitic acid to stearic acid is 3-4:1. The cream cheese is subjected to gradient temperature recovery ripening after filling, and the specific process is as follows: after filling, the cream cheese is cooled to 4-6 DEG C at a cooling rate of 1-2 DEG C / min, then is heated to 12-15 DEG C at a heating rate of 0.1-0.6 DEG C / min, is kept for 4-6 h, and is cooled to 4-6 DEG C again at a cooling rate of 0.6-2.2 DEG C / min. The cream cheese disclosed by the application has a more concentrated and layered flavor, and has a delicate and soft texture and good spreadability.

The present invention provides a wax composition for cosmetics that can suppress the deterioration of storage stability of cosmetics in low-temperature, low-humidity or high-temperature, high-humidity environments, and improve the washability of cosmetics. [Solution] A cosmetic wax composition containing an ester of a linear saturated fatty acid having 14 to 26 carbon atoms and pentaerythritol, wherein the ester contains tetraester T, the content of tetraester T in the wax composition is 80 to 98% by mass, the wax composition has an acid value of 2 mg KOH / g or less, a hydroxyl value of 1 mg KOH / g or more and 10 mg KOH / g or less, and a melting point of 75°C or higher.