12 results about "Elevated blood" patented technology

The invention belongs to the field of biological medicine, and discloses a blood marker for identifying epilepsy convulsion and application thereof. The inventor finds that the LRG1 is obviously increased during epileptic convulsion, which indicates that the increase of the blood LRG1 is a blood marker during the acute attack stage of epileptic convulsion. The invention proposes and verifies that the LRG1 is the peripheral blood marker in the acute attack stage of epilepsy convulsion for the first time, and can be used as a clinical auxiliary diagnosis and treatment target.

The invention belongs to the field of biological medicine industry, and discloses a peripheral blood marker and system for identifying the severity of viral myocarditis or coronary artery stenosis. The inventor finds for the first time that the average value of LRG1 in blood is not obviously changed compared with that of a normal person when mild and moderate myocarditis and microcirculation angina pectoris with normal coronary artery or coronary artery stenosis smaller than 10% exist, and the blood LRG1 is obviously increased when the coronary artery stenosis of the coronary heart disease exceeds 70%; when severe myocarditis occurs, the blood LRG1 is also obviously increased, so that the increase of the blood LRG1 is a blood marker for patients with severe myocarditis or severe coronary artery lesion, and the blank that blood indexes are lacked in the prior art to prompt the patients to have severe coronary artery stenosis is filled. By detecting the LRG1 content of the peripheral blood and combining with other conventional examinations, the severity of myocarditis or coronary stenosis can be simply, accurately and quickly distinguished, and a corresponding basis is provided for subsequent accurate treatment.

The present disclosure relates to a device assembly and a method for treating heart failure by normalizing elevated blood pressure in the left atrium of a heart of a mammal. Disclosed herein is a transcatheter interatrial septum excision device assembly configured to create a sized interatrial aperture between the right and left atria of a heart for the relief of elevated left atrial pressure. The device assembly comprises a delivery catheter, a tissue stabilizer attached to a first catheter having a central lumen and a penetrating tip that permits passage of a guidewire, and a cutter attached to a second catheter having a central lumen that permits passage of the first catheter. Alternative configurations comprise a (third) catheter having a central lumen that permits passage of the aforementioned components to and from the right atrium, a tissue retention mechanism and an optional coaxial alignment mechanism.

This invention discloses a camel milk formula powder for assisting in the regulation of blood lipids and its preparation process, belonging to the field of functional dairy product deep processing technology. This formula powder constructs a five-in-one synergistic lipid-regulating network of "exogenous absorption inhibition, endogenous synthesis regulation, oxidative stress protection, intestinal microecological regulation, and vascular endothelial protection." Its core components include a specific ratio of compounded phytosterol esters, microencapsulated complex oils, and medicinal and edible extracts. The preparation process employs stepwise low-temperature microencapsulation and cold spray agglomeration granulation technology to achieve full-process low-temperature protection of active ingredients, with lactoferrin retention ≥90% and ω-3 fatty acid bioavailability increased by more than 25%. This invention's product has comprehensive lipid-regulating effects, 3 times improved oxidative stability, and produces no oil residue or off-odor when mixed, making it suitable for long-term consumption by people with borderline elevated blood lipids. It can also achieve continuous industrial production with a batch mixing uniformity RSD ≤2%.

The invention discloses targeted prebiotic plant extraction dietary powder for conditioning hypertension and a preparation method thereof. According to the present invention, the lactobacillus plantarum CECT5716, the bifidobacterium lactis BLa80 and other strains selected in the formula can regulate the renin-angiotensin system balance by inhibiting the activity of the angiotensin converting enzyme so as to reduce the vasosystolic pressure from the neuroendocrine level; hawthorn flavone and pueraria isoflavone directly act on blood vessels to expand peripheral arteries, improve coronary artery blood flow and enhance blood vessel elasticity; the gamma-aminobutyric acid serving as a neurotransmitter can relieve sympathetic nerve hyperexcitation and reduce blood pressure fluctuation caused by emotion or pressure. Meanwhile, prebiotics such as resistant dextrin provide nutrients for probiotics, promote generation of intestinal short-chain fatty acids, activate a vascular endothelium protection pathway through an intestinal-metabolic axis, form a triple antihypertensive network of strain regulation, plant intervention and flora synergy, and cover different pathological links of blood pressure rise.

The present teaching provides devices and methods for treating heart disease by normalizing elevated blood pressure in the left and right atria of a heart. Various embodiments of the devices allow left-to-right blood flow through their flow elements. The flow element of the device is designed to self-adjust the amount of blood flow in response to the left atrial pressure fluctuation.

The present disclosure relates to a device assembly and a method for treating heart failure by normalizing elevated blood pressure in the left atrium of a heart of a mammal. Disclosed herein is a RF energy-based transcatheter interatrial septum excision device configured to create a sized interatrial aperture between the right and left atria of a heart for the relief of elevated left atrial pressure. The device assembly comprises a delivery catheter, a tissue stabilizer attached to a tissue stabilizer catheter, a tissue cutter attached to a tissue cutter catheter, a remotely located RF generator connected to an RF cathode and anode of the device assembly.

A specially prepared herbal tea (1.5 g) for patients with Type II diabetes mellitus is derived from Gymnema lactiferum leaves. This tea was utilized in a randomized, double blind, controlled clinical trial at the Diabetic Center, Teaching Hospital Jaffna, Sri Lanka. In this trial, participants were randomly divided into two groups: one group received one cup of herbal tea per day in addition to their conventional medications, while the other group received one cup of green tea as an active control for three months. Blood samples were analyzed according to the schedule outlined in the mode of intervention, which helped achieve better glycemic control in uncontrolled or poorly controlled diabetes, along with a decrease in total cholesterol, LDL cholesterol, and triglycerides. Blood pressure was reduced in patients with elevated blood pressure, and body weight decreased, with no significant reduction in HDL cholesterol among Type II diabetes mellitus patients.

The application belongs to the field of molecular diagnosis, and discloses application of a blood marker in preparation of a diagnostic reagent for idiopathic benign paroxysmal positional vertigo. It is found for the first time that LRG1 in blood is obviously increased in the acute attack period of idiopathic benign paroxysmal positional vertigo, which indicates that the increase of blood LRG1 is a blood marker for dizziness of idiopathic benign paroxysmal positional vertigo, and can be used as auxiliary diagnosis in clinic.

The present invention relates to compositions comprising microorganisms for use in reducing blood urate concentration. These compositions can be used in the therapeutic and prophylactic treatment of subjects at risk of, or suffering from, elevated blood urate levels. The compositions can be pharmaceutical or nutraceutical compositions for the treatment and prevention of urate and hyperuricemia related diseases such as cardiovascular disease, metabolic syndrome, non-alcoholic fatty liver disease, chronic kidney disease, gout, insulin resistance, hypertension, dyslipidemia, renal insufficiency, obesity, prediabetes and diabetes.

This invention discloses a traditional Chinese medicine composition for improving blood sugar, its preparation method, and its application, belonging to the field of traditional Chinese medicine compound technology. The composition is prepared by combining scorpion, centipede, jujube seed, dandelion, cardamom, and platycodon in specific weight proportions. Based on the pathological mechanism of integrated traditional Chinese and Western medicine, this invention establishes liver phlegm obstruction, abnormal liver qi rising, and liver stagnation with internal heat disturbing the hypothalamus as the core pathogenesis of type 2 diabetes. Phlegm and dampness stagnation in the liver collaterals leads to impaired liver glycogen synthesis, and compensatory hyperactivity of the hypothalamus causes elevated blood sugar, polyphagia, and polydipsia. Deficiency of peripheral fluids and blood induces muscle atrophy and prediabetic foot lesions. This invention abandons the drawbacks of traditional yin-nourishing drugs that are greasy and promote dampness, using insect-derived drugs to clear phlegm and dampness from the liver collaterals, combined with herbs that clear the liver, nourish the liver, strengthen the spleen, and promote lung function. It regulates glucose metabolism at multiple targets, calms hypothalamic central hyperactivity, and nourishes the extremities. This formula can be prepared at home. It has a mild medicinal effect, stabilizes blood sugar, improves dry mouth and excessive appetite, numbness and atrophy of limbs, and slows the progression of diabetic foot. It has clinical application and industrial transformation value.

To provide a composition having remarkably improved elevated blood cholesterol level inhibitory action.SOLUTION: A composition comprising chitosan and at least one material selected from the group consisting of the following (a) and (b): (a) at least one functional material selected from the group consisting of resveratrol, lycopene, soybean isoflavone, nattokinase, cacao polyphenol, octacosanol, fucoidan, and citrulline; and SELECTED DRAWING: Figure 1