92 results about "Left atrial" patented technology

An occlusion device with particular utility in occlusion of left atrial appendages is described. The occlusion device embodiments utilize an inflatable balloon or expandable element used to occlude the treatment site.

A method includes inserting a contact member into an anatomical cavity. The contact member is rotated within the anatomical cavity through a first range of angular motion and engages tissue of the anatomical cavity during such rotation, such that rotation of the contact member within the anatomical cavity through the first range of angular motion causes torsional deformation of the anatomical cavity. The contact member is moved longitudinally through a first range of longitudinal motion after rotating the contact member within the anatomical cavity through the first range of angular motion, thereby causing longitudinal deformation of the anatomical cavity. A position of the contact member is secured relative to the tissue, thereby maintaining the torsional and longitudinal deformation of the tissue.

Systems, devices and methods for occluding the left atrial appendage (LAA). The device excludes the LAA from blood flow. The implantable device is delivered via transcatheter delivery into the LAA and secured within the LAA. The implant comprises an expandable and compliant frame having anchors and an expandable and conformable tubular foam body. A delivery and tether retraction system includes a handle for controlling a pusher and tether. The pusher may be moved a distance away from the implant without changing the orientation of the implant, while the tether is still attached to the implant. A loader includes a conical portion with guides and a reservoir for submerging the foam implant prior to loading and delivery.

The invention discloses a foaming test device and system. According to the foaming test device, left / right atrial angiography tests can be taken into consideration at the same time, and when the foaming test device is switched into the left atrial angiography working mode, normal saline and a contrast agent can be automatically mixed to form a left atrial angiography mixed solution, and a left atrial angiography foaming solution is further formed; when the foaming test device is switched into a right atrial angiography working mode, normal saline, air and blood can be automatically mixed to form a right atrial angiography mixed solution, and a right atrial angiography foaming solution is further formed; the first injector and the second injector are matched with each other to perform reciprocating injection, so that the foaming efficiency of the left / right atrial angiography mixed liquid can be effectively improved, the time for forming the bubble liquid is shortened, automatic preparation of the left / right atrial angiography bubble liquid is quickly realized, meanwhile, the quality, preparation efficiency and consistency of the bubble liquid can be improved, and the production cost is reduced. And the accuracy of auxiliary screening is improved.

An integrated transcatheter valve replacement and Piezoelectric Micro-Machined Ultrasonic Transducer (pMUT) enabled ultrasonic imaging system, is disclosed. The system comprising a transcatheter valve replacement assembly having a longitudinal axis, a proximal end, and a distal end. The transcatheter valve replacement assembly comprises a self-expanding valve, a frame and leaflets. A micro-electromechanical (MEMS) based pMUT transducer having MEMS based pMUT array disposed within the distal end of the transcatheter valve replacement assembly. The MEMS based pMUT array comprises a substrate and a plurality of pMUT array elements arranged on the substrate. The integrated transcatheter valve replacement and pMUT enabled ultrasonic imaging system is used in left atrial appendage (LAA), atrial septal defect (ASD), transcatheter aortic valve replacement (TAVR), transcatheter mitral value replacement (TMVR), and transcatheter tricuspid valve replacement (TTVR) or other catheterized structural heart procedures.

The invention discloses a heart semi-supervised segmentation method fusing a double-teacher model and weighted label fusion, and belongs to the technical field of medical image processing, and the method comprises the steps: obtaining a heart or left atrium MRI image set of a unified size, carrying out the label processing, and carrying out the data set division operation; constructing a student network; constructing a double-teacher network; the double-teacher network comprises a teacher model A and a teacher model B which run independently; the network structures of the teacher model A and the teacher model B are the same as the student network; designing a heart segmentation network model according to the student model and the double-teacher model; and training the heart segmentation network model by using a data set division operation result, and verifying the model. According to the method, the network segmentation performance can be effectively improved in a limited annotation data situation, and the method is particularly suitable for complex medical scenes such as heart or left atrium MRI and has wide clinical application value and good development prospects.

Disclosed herein are systems and methods for applying an occlusion clip. The medical device can comprise a handle, an elongated shaft extending from the handle, the elongated shaft comprising a proximal end, a distal end, and a central lumen. The medical device can further comprise an end effector at the distal end of the elongated shaft, the end effector comprising a first jaw and a second jaw configured to engage with and deliver the occlusion clip to a target tissue, wherein the end effector comprises a link mechanism configured to move the first jaw and the second jaw relative to each other. The medical device can further comprise a plurality of cables extending through the central lumen. The medical device can further comprise an articulation plate coupled to the handle. The medical device can further comprise an articulation joint coupling the articulation plate and the elongated shaft.

The invention discloses an edge-enhanced left atrial appendage medical image segmentation method and system and a storage medium, and the method comprises the steps: constructing a convolutional neural network model of a U-shaped coding structure based on an attention mechanism and a weight loss function, and recording the model as EMCLUNet + +; the medical image segmentation model (EMCLUNet + +) based on edge enhancement adopts an improved UNet + + as a backbone network, and comprises a convolution encoder module, a decoder part, a multi-scale attention module EMSA and an efficient attention mechanism module Clotion. And transmitting a medical image to be segmented into the trained convolutional neural network model to obtain a segmentation result. According to the method, redundant information interference is reduced and the accuracy of boundary information is improved by utilizing a channel and a space attention mechanism. For conditions (such as pericardial effusion or pleural effusion of a patient) with complications, the robustness to complex backgrounds and noise is enhanced by the multi-scale feature fusion and lightweight module, and a high-quality segmentation result is ensured.

An implant (1) for occluding a left atrial appendage comprises a radially expansible element (2) configured to shift between a collapsed configuration and an expanded configuration. The radially expansible element (2) comprises a pair of core elements (3) which extends in direction of a longitudinal axis (4) and which have a tubular shape. The pair of core elements (3) comprises a first core element (5) and a second core element (6). The first and second core elements (5, 6) are stacked in direction of said longitudinal axis (4). The pair of core elements (3) has an outer circumference (7) and the first core element (5) and the second core element (6) each enclose a cavity (8). The first core element (5) and the second core element (6) are rotatable relative to one another. The radially expansible element (2) further comprises a driving and locking element arranged in the respective cavities (8) of the pair of core elements (3) for rotating the first core element (5) and the second core element (6) relative to one another so as to move the radially expansible element (2) from the collapsed configuration into the expanded configuration and for locking the first core element (5) and the second core element (6) relative to one another, wherein the driving and locking element is adapted for being engaged with a rotatable pin mounted at the tip of an elongated catheter member.

A blood flow pathway is formed between a left atrium and a coronary sinus for relieving elevated left atrial pressure. The treatment method includes providing first and second delivery catheters, wherein a medical device is carried by the second delivery catheter. A side outlet opening of the first delivery catheter is positioned within the coronary sinus and oriented toward a left atrium. An anchor on the first delivery catheter contacts an inner surface of the coronary sinus for stabilization. A distal portion of the second delivery catheter is advanced through the side outlet opening. A puncture component is then passed through a target wall portion for creating the blood flow pathway. The medical device is positioned in the opening.

A blood flow pathway is formed between a left atrium and a coronary sinus for relieving elevated left atrial pressure. The treatment method includes providing first and second delivery catheters, wherein a medical device is carried by the second delivery catheter. A side outlet opening of the first delivery catheter is positioned within the coronary sinus and oriented toward a left atrium. An anchor on the first delivery catheter contacts an inner surface of the coronary sinus for stabilization. A distal portion of the second delivery catheter is advanced through the side outlet opening. A puncture component is then passed through a target wall portion for creating the blood flow pathway. The medical device is positioned in the opening.

A left atrial appendage ligator having a ligature and operating handle. One end of the operating handle is fixedly connected with a support rod, the inner wall of the support rod is fixedly connected with a feeding pipe and locking pipe. A first sliding groove is formed in the inner side wall of the feeding pipe. The inner side wall of the first sliding groove is slidably connected with a first sliding block. The middle part of the first sliding block is fixedly connected with a feeding push rod. One end of the feeding push rod is fixedly connected with a first hook. One side of the first sliding block is fixedly connected with a return spring. The left atrial appendage ligator has a locking push rod, ligature, hanger knot and supporting component. The ligature is prearranged on a sleeve pipe portion to form the hanger knot to avoid knotting during the operation process. During operation, the knotting can be completed only by locking the hanger knot. The sleeve pipe portion serves as support for threading the other end of the ligature to avoid automatic locking. After the sleeve pipe portion is separated from the hanger knot, the hanger knot can be pulled for automatic locking.

The utility model discloses a left atrial appendage occluder conveying sheathing canal shaping device which comprises heating plates which are oppositely arranged, a bent section shaping block and a straight section shaping block which are sequentially arranged between the plate faces of the heating plates in the shaping direction of a conveying sheathing canal, and shaping grooves are correspondingly formed in the bent section shaping block and the straight section shaping block. A shaping area of the conveying sheath tube is positioned through the shaping groove, an angle shaping block for shaping and fixing the torsion angle of the end of the conveying sheath tube relative to the straight section is arranged on the straight section shaping block, and the angle shaping block and the straight section shaping block are connected in a rotating fit mode and are rotationally positioned through an arranged angle limiting mechanism. According to the utility model, through the modular design, the shaping part for conveying the sheathing canal is separately and independently designed, a user can flexibly adjust the angle according to the requirements of different patients, and the complex operation of needing various sheathing canals is avoided, so that the left auricle anatomical structure of different patients can be adapted, and the requirements on various sheathing canals are reduced.

A blood flow pathway is formed between a left atrium and a coronary sinus for relieving elevated left atrial pressure. The treatment method includes providing first and second delivery catheters, wherein a medical device is carried by the second delivery catheter. A side outlet opening of the first delivery catheter is positioned within the coronary sinus and oriented toward a left atrium. An anchor on the first delivery catheter contacts an inner surface of the coronary sinus for stabilization. A distal portion of the second delivery catheter is advanced through the side outlet opening. A puncture component is then passed through a target wall portion for creating the blood flow pathway. The medical device is positioned in the opening.

The present invention relates to a system for detecting leakage around an occlusive implant disposed in the left atrial appendage. The system comprises an elongate shaft (34), and a first sensor (30). The elongate shaft (34) has a port (56) disposed at a distal end region thereof. The first sensor (30) is disposed adjacent the elongate shaft (34). The elongate shaft (34) is configured to be positioned adjacent the occlusive implant (10) such that the first sensor (30) is positioned on a first side of the occlusive implant (10), and wherein the port (56) is positioned on a second side of the occlusive implant (10). The first sensor (30) is configured to measure a first parameter. The first parameter (30) is utilized to determine a fluid leak between the occlusive implant (10) and a tissue wall defining the left atrial appendage (50). The elongate shaft (34) includes a core wire (18) and a second sensor (32), wherein the core wire (18) is coupled to the occlusive implant (10), and wherein the first sensor (30) is disposed on the core wire (18) on the first side of the implant (10), and wherein the second sensor (32) is disposed on the core wire (18) on the second side of the implant (10).

An occlusion device for occluding a left atrial appendage extending from a lateral wall of a left atrium of a heart including a first clamping portion and a second clamping portion movably connected to one another and configured for positioning along opposed sides of the left atrial appendage. The first clamping portion and the second clamping portion each may include an inner side configured to face toward the left atrial appendage when the device is in a deployed configuration, an outer side disposed opposite the inner side and configured to face away from the left atrial appendage when the device is in the deployed configuration. A pair of sleeves may be coupled to the outer side of each clamping portion. Each sleeve defines a channel configured to accept a medical tool to facilitate moving the device between an open and closed configuration.

The present invention relates to a medical implant for occluding a left atrial appendage, comprising: an expandable framework configured to shift between a collapsed configuration and an expanded configuration; a plurality of anchor members disposed along the expandable framework; a covering disposed along an outer surface of the expandable framework; and a protrusion portion extending outward from the covering.

The utility model belongs to the technical field of medical instruments, and particularly discloses a novel single-disc patent foramen ovale plugging device which structurally comprises a front disc, a rear support, a waist portion connecting the front disc and the rear support, a flow blocking film arranged in the front disc and wrapping the rear support, and a screw arranged on the outer side of the rear support. The front disc of the plugging device covers the left chamber outlet of the oval foramen after being unfolded, and shunting can be stopped as much as possible; the rear support in the right atrial septum is clamped on the right atrial septum after being unfolded, and the disc face of the left atrial septum is more tightly attached to the left atrial exit of the oval hole under the action of traction force of the rear support. Compared with a traditional foramen ovale plugging device, the foramen ovale plugging device can reduce shunting and thrombosis, and is better in applicability to long and narrow foramen ovale.

The invention relates to the technical field of medical treatment, and discloses a construction method of a left auricle hemodynamics simulation system, which comprises the following core steps of: firstly, acquiring noninvasive transthoracic echocardiography and cardiac enhancement CT (Computed Tomography) image data of a patient; secondly, through an image fusion technology, an accurate left auricle three-dimensional geometric structure model is constructed; and finally, on the basis of the model, carrying out hemodynamic simulation on the left atrium and the left auricle by utilizing a CFD (Computational Fluid Dynamics) technology, and accurately calculating hemodynamic parameters such as the blood flow velocity at the opening of the left auricle. The method has the advantages that the blood flow state of the left atrial appendage is evaluated completely, noninvasively, accurately and quantitatively, and traditional invasive transesophageal ultrasonic examination can be effectively replaced. According to the method, the comfort level of the patient and the examination safety are remarkably improved, operation related risks are avoided, meanwhile, the screening feasibility and efficiency are improved, and the method has important value for clinical management of the stroke risk of the atrial fibrillation patient.

The present invention relates to left atrial appendage closure guidance in medical imaging. An ultrasound imager (20) provides LAA closure guidance. Modeling (32) is performed using ultrasound imaging to allow for time (e.g., throughout the heart cycle). The anatomical model of the LAA over time is used to create a biomechanical model personalized for the patient. The personalized model and models of one or more closure devices are used to select (40) a closure device for the patient that is appropriate for the entire heart cycle and to guide (44) the placement of the selected closure device during implantation.

Devices and methods are described for occluding the left atrial appendage (LAA). The device excludes the LAA from blood flow to prevent blood from clotting within the LAA and subsequently embolizing, particularly in patients with atrial fibrillation. The implantable device is delivered via transcatheter delivery into the LAA and secured within the LAA. The implant comprises an expandable and compliant frame and an expandable and conformable tubular foam body carried by the frame. The device may have a thromboresistant cover at a proximal end and a thromboresistant coating on the foam body. The frame may have recapture struts inclining radially outwardly in the distal direction from a central hub. The frame may have axially extending side wall struts, with adjacent pairs of side wall struts joined at one or more apexes. Anchors extend from the frame to engage tissue. The anchors can also be reversible to allow retraction of the anchors and repositioning or retrieval of the device.

The invention discloses a left atrial appendage closer, and belongs to the field of medical instruments. The left auricle closer comprises a conveying catheter, a supporting pipe, a supporting disc, a telescopic supporting rod, a closing clamp assembly and a control pull wire, a closing clamp can be fed into an opening of a left auricle through the conveying catheter, and the opening of the left auricle is opened through cooperation of the telescopic supporting rod and the control pull wire; according to the left atrial appendage closure device, the puncture hook needle in the closure clamp is used for puncturing the tissue wall of the left atrial appendage opening to achieve combination, finally the left atrial appendage opening is closed through linear closing of the closure clamp, and compared with an existing left atrial appendage closure device, the puncture hook needle on the periphery of the closure clamp can puncture the tissue in the radial direction, the closure clamp is used for driving the left atrial appendage opening to be closed, and the left atrial appendage opening is closed. The left atrial appendage closing clamp has the advantages that the left atrial appendage closing clamp is more firmly connected with the left atrial appendage and is not easy to fall off, the problem that the sealing reliability of the left atrial appendage is reduced due to looseness or movement is solved, long-term effectiveness of left atrial appendage closing is guaranteed, and complications caused by falling off and unreliable sealing are reduced.

The invention relates to a left atrial appendage occluder which comprises an occluding disc, a connecting mechanism and a filling module, and the occluding disc is connected with the filling module through the connecting mechanism; the filling module comprises at least one filling unit, all the filling units are connected in series, and the filling module is used for filling the whole left auricle; by arranging the plugging disc and the filling module, the number and the size of the filling units in the filling module can be customized according to the lesion shape of the left auricle, so that the lesion space is better filled, and the plugging effect of the left auricle is achieved in cooperation with the plugging disc; the polyurethane foam is arranged in the plugging disc, so that plug-forming plugging can be quickly realized, the endothelialization process can be accelerated, and meanwhile, the filling unit made of the polyurethane foam can also accelerate closing of the whole cavity.

The implantable medical device comprises an expandable frame movable between a collapsed configuration for delivery, an expanded configuration for deployment, and an expanded configuration, the expandable frame comprising a first frame end and a second frame end, a distance between the first frame end and the second frame end while in the expanded configuration defining an expanded configuration end distance, and a distance between the first frame end and the second frame end while in the expanded configuration defining an expanded configuration end distance, a support member extending between the first frame end and the second frame end, the support member comprising a first end secured to the first frame end and a second end releasably securable to the second frame end, the adjustable support adapted to limit the expanded configuration end distance relative to the expanded configuration end distance.

An integrated transcatheter valve replacement and Piezoelectric Micro-Machined Ultrasonic Transducer (pMUT) enabled ultrasonic imaging system, is disclosed. The system comprising a transcatheter valve replacement assembly having a longitudinal axis, a proximal end, and a distal end. The transcatheter valve replacement assembly comprises a self-expanding valve, a frame and leaflets. A micro-electromechanical (MEMS) based pMUT transducer having MEMS based pMUT array disposed within the distal end of the transcatheter valve replacement assembly. The MEMS based pMUT array comprises a substrate and a plurality of pMUT array elements arranged on the substrate. The integrated transcatheter valve replacement and pMUT enabled ultrasonic imaging system is used in left atrial appendage (LAA), atrial septal defect (ASD), transcatheter aortic valve replacement (TAVR), transcatheter mitral value replacement (TMVR), and transcatheter tricuspid valve replacement (TTVR) or other catheterized structural heart procedures.

A left atrial appendage closure implant may include a support frame including a first bend extending from a proximal collar to a second bend, a first segment extending from the second bend to a third bend, a second segment extending from the third bend to a fourth bend, and a third segment extending from the fourth bend to a distal collar, wherein the support frame is actuatable from a first constrained position to a second flowering position to a third mid-deployment position to a fourth unconstrained position. An implant may include a self-expanding support frame having a circumference and a central longitudinal axis, a membrane disposed over at least a portion of the support frame, and a plurality of anchors arranged into a first row and a second row such that the first row and the second row form a staggered pattern about the circumference of the support frame.

The application provides a guide system for patent foramen ovale (PFO) interventional closure device guide wire, which comprises a sheath tube dilator assembly, a guide tube component, a first guide wire and a second guide wire; the sheath tube dilator assembly comprises a fixed sheath tube component and a dilator component, the tube structure of the dilator component is arranged in the tube structure of the fixed sheath tube component; the sheath tube dilator assembly has an operation part for controlling the movement of the distal end of the sheath tube dilator assembly to the fossa ovalis of the atrial septum; the tube structure of the guide tube component is rotatably and slidably arranged in the tube structure of the dilator component, and the distal end of the guide tube component is used for entering the PFO tunnel from the fossa ovalis of the atrial septum, thereby establishing a left atrial passage. The application can significantly improve the success rate and efficiency of the operation, and effectively solves the guide wire passing difficulty problem caused by the small size, adhesion or anatomical variation of the PFO tunnel by using the step-by-step strategy of first mechanically expanding the PFO tunnel by using the guide tube component and then exploring the path by using the second guide wire.

A method of treating a tissue of the heart, for example and without limitation, a tissue of the left atrial appendage, includes twisting at least a portion of a tissue of the left atrial appendage to constrict an ostium of the left atrial appendage, and ablating at least a portion of the tissue of the heart, which can include a tissue of the left atrial appendage, the ostium of the left atrial appendage, and / or at least a portion of a tissue adjacent to the ostium of the left atrial appendage.

The application provides a method for fixing an interventional valve on a mitral valve, which comprises the following steps: driving a plurality of fixing nails into the left atrial side wall above the mitral valve; and connecting a fixing disc on the atrial septum through a connecting line to form a plurality of fixing lines above the mitral valve. The fixing method can form a plurality of fixing lines above the mitral valve, and the fixing lines can provide stable fixing support for the interventional valve implanted below, thereby effectively solving the problem that the current interventional mitral valve is difficult to be stably anchored, and the method for fixing the interventional valve on the mitral valve is simple and convenient to operate.

A left atrial appendage closure device adapted for occluding the left atrial appendage includes a cone-shaped insert formed of an expandable foam and adapted for trans-septal delivery to the LAA. A polymeric covering is disposed over the cone-shaped insert, the polymeric covering adapted to protect the cone-shaped insert during trans-septal delivery to the LAA, the polymeric covering adapted for removal after trans-septal delivery to the LAA. An insert lumen extends through the cone-shaped insert prior to expansion of the cone-shaped insert. A tubular support rod extends through the insert lumen, the tubular support rod operably coupled with at least a portion of the polymeric covering, the tubular support rod itself defining a tubular support rod lumen adapted to accommodate a guidewire over which the insert may be advanced into the LAA and / or a radio frequency (RF) energy wire adapted for making a trans-septal puncture.