54 results about "Left atrial" patented technology

An occlusion device with particular utility in occlusion of left atrial appendages is described. The occlusion device embodiments utilize an inflatable balloon or expandable element used to occlude the treatment site.

A method includes inserting a contact member into an anatomical cavity. The contact member is rotated within the anatomical cavity through a first range of angular motion and engages tissue of the anatomical cavity during such rotation, such that rotation of the contact member within the anatomical cavity through the first range of angular motion causes torsional deformation of the anatomical cavity. The contact member is moved longitudinally through a first range of longitudinal motion after rotating the contact member within the anatomical cavity through the first range of angular motion, thereby causing longitudinal deformation of the anatomical cavity. A position of the contact member is secured relative to the tissue, thereby maintaining the torsional and longitudinal deformation of the tissue.

The invention discloses a heart semi-supervised segmentation method fusing a double-teacher model and weighted label fusion, and belongs to the technical field of medical image processing, and the method comprises the steps: obtaining a heart or left atrium MRI image set of a unified size, carrying out the label processing, and carrying out the data set division operation; constructing a student network; constructing a double-teacher network; the double-teacher network comprises a teacher model A and a teacher model B which run independently; the network structures of the teacher model A and the teacher model B are the same as the student network; designing a heart segmentation network model according to the student model and the double-teacher model; and training the heart segmentation network model by using a data set division operation result, and verifying the model. According to the method, the network segmentation performance can be effectively improved in a limited annotation data situation, and the method is particularly suitable for complex medical scenes such as heart or left atrium MRI and has wide clinical application value and good development prospects.

A blood flow pathway is formed between a left atrium and a coronary sinus for relieving elevated left atrial pressure. The treatment method includes providing first and second delivery catheters, wherein a medical device is carried by the second delivery catheter. A side outlet opening of the first delivery catheter is positioned within the coronary sinus and oriented toward a left atrium. An anchor on the first delivery catheter contacts an inner surface of the coronary sinus for stabilization. A distal portion of the second delivery catheter is advanced through the side outlet opening. A puncture component is then passed through a target wall portion for creating the blood flow pathway. The medical device is positioned in the opening.

A blood flow pathway is formed between a left atrium and a coronary sinus for relieving elevated left atrial pressure. The treatment method includes providing first and second delivery catheters, wherein a medical device is carried by the second delivery catheter. A side outlet opening of the first delivery catheter is positioned within the coronary sinus and oriented toward a left atrium. An anchor on the first delivery catheter contacts an inner surface of the coronary sinus for stabilization. A distal portion of the second delivery catheter is advanced through the side outlet opening. A puncture component is then passed through a target wall portion for creating the blood flow pathway. The medical device is positioned in the opening.

The utility model discloses a left atrial appendage occluder conveying sheathing canal shaping device which comprises heating plates which are oppositely arranged, a bent section shaping block and a straight section shaping block which are sequentially arranged between the plate faces of the heating plates in the shaping direction of a conveying sheathing canal, and shaping grooves are correspondingly formed in the bent section shaping block and the straight section shaping block. A shaping area of the conveying sheath tube is positioned through the shaping groove, an angle shaping block for shaping and fixing the torsion angle of the end of the conveying sheath tube relative to the straight section is arranged on the straight section shaping block, and the angle shaping block and the straight section shaping block are connected in a rotating fit mode and are rotationally positioned through an arranged angle limiting mechanism. According to the utility model, through the modular design, the shaping part for conveying the sheathing canal is separately and independently designed, a user can flexibly adjust the angle according to the requirements of different patients, and the complex operation of needing various sheathing canals is avoided, so that the left auricle anatomical structure of different patients can be adapted, and the requirements on various sheathing canals are reduced.

A blood flow pathway is formed between a left atrium and a coronary sinus for relieving elevated left atrial pressure. The treatment method includes providing first and second delivery catheters, wherein a medical device is carried by the second delivery catheter. A side outlet opening of the first delivery catheter is positioned within the coronary sinus and oriented toward a left atrium. An anchor on the first delivery catheter contacts an inner surface of the coronary sinus for stabilization. A distal portion of the second delivery catheter is advanced through the side outlet opening. A puncture component is then passed through a target wall portion for creating the blood flow pathway. The medical device is positioned in the opening.

An occlusion device for occluding a left atrial appendage extending from a lateral wall of a left atrium of a heart including a first clamping portion and a second clamping portion movably connected to one another and configured for positioning along opposed sides of the left atrial appendage. The first clamping portion and the second clamping portion each may include an inner side configured to face toward the left atrial appendage when the device is in a deployed configuration, an outer side disposed opposite the inner side and configured to face away from the left atrial appendage when the device is in the deployed configuration. A pair of sleeves may be coupled to the outer side of each clamping portion. Each sleeve defines a channel configured to accept a medical tool to facilitate moving the device between an open and closed configuration.

The invention relates to the technical field of medical treatment, and discloses a construction method of a left auricle hemodynamics simulation system, which comprises the following core steps of: firstly, acquiring noninvasive transthoracic echocardiography and cardiac enhancement CT (Computed Tomography) image data of a patient; secondly, through an image fusion technology, an accurate left auricle three-dimensional geometric structure model is constructed; and finally, on the basis of the model, carrying out hemodynamic simulation on the left atrium and the left auricle by utilizing a CFD (Computational Fluid Dynamics) technology, and accurately calculating hemodynamic parameters such as the blood flow velocity at the opening of the left auricle. The method has the advantages that the blood flow state of the left atrial appendage is evaluated completely, noninvasively, accurately and quantitatively, and traditional invasive transesophageal ultrasonic examination can be effectively replaced. According to the method, the comfort level of the patient and the examination safety are remarkably improved, operation related risks are avoided, meanwhile, the screening feasibility and efficiency are improved, and the method has important value for clinical management of the stroke risk of the atrial fibrillation patient.

The invention discloses a left atrial appendage closer, and belongs to the field of medical instruments. The left auricle closer comprises a conveying catheter, a supporting pipe, a supporting disc, a telescopic supporting rod, a closing clamp assembly and a control pull wire, a closing clamp can be fed into an opening of a left auricle through the conveying catheter, and the opening of the left auricle is opened through cooperation of the telescopic supporting rod and the control pull wire; according to the left atrial appendage closure device, the puncture hook needle in the closure clamp is used for puncturing the tissue wall of the left atrial appendage opening to achieve combination, finally the left atrial appendage opening is closed through linear closing of the closure clamp, and compared with an existing left atrial appendage closure device, the puncture hook needle on the periphery of the closure clamp can puncture the tissue in the radial direction, the closure clamp is used for driving the left atrial appendage opening to be closed, and the left atrial appendage opening is closed. The left atrial appendage closing clamp has the advantages that the left atrial appendage closing clamp is more firmly connected with the left atrial appendage and is not easy to fall off, the problem that the sealing reliability of the left atrial appendage is reduced due to looseness or movement is solved, long-term effectiveness of left atrial appendage closing is guaranteed, and complications caused by falling off and unreliable sealing are reduced.

The invention relates to a left atrial appendage occluder which comprises an occluding disc, a connecting mechanism and a filling module, and the occluding disc is connected with the filling module through the connecting mechanism; the filling module comprises at least one filling unit, all the filling units are connected in series, and the filling module is used for filling the whole left auricle; by arranging the plugging disc and the filling module, the number and the size of the filling units in the filling module can be customized according to the lesion shape of the left auricle, so that the lesion space is better filled, and the plugging effect of the left auricle is achieved in cooperation with the plugging disc; the polyurethane foam is arranged in the plugging disc, so that plug-forming plugging can be quickly realized, the endothelialization process can be accelerated, and meanwhile, the filling unit made of the polyurethane foam can also accelerate closing of the whole cavity.

The application provides a guide system for patent foramen ovale (PFO) interventional closure device guide wire, which comprises a sheath tube dilator assembly, a guide tube component, a first guide wire and a second guide wire; the sheath tube dilator assembly comprises a fixed sheath tube component and a dilator component, the tube structure of the dilator component is arranged in the tube structure of the fixed sheath tube component; the sheath tube dilator assembly has an operation part for controlling the movement of the distal end of the sheath tube dilator assembly to the fossa ovalis of the atrial septum; the tube structure of the guide tube component is rotatably and slidably arranged in the tube structure of the dilator component, and the distal end of the guide tube component is used for entering the PFO tunnel from the fossa ovalis of the atrial septum, thereby establishing a left atrial passage. The application can significantly improve the success rate and efficiency of the operation, and effectively solves the guide wire passing difficulty problem caused by the small size, adhesion or anatomical variation of the PFO tunnel by using the step-by-step strategy of first mechanically expanding the PFO tunnel by using the guide tube component and then exploring the path by using the second guide wire.

A method of treating a tissue of the heart, for example and without limitation, a tissue of the left atrial appendage, includes twisting at least a portion of a tissue of the left atrial appendage to constrict an ostium of the left atrial appendage, and ablating at least a portion of the tissue of the heart, which can include a tissue of the left atrial appendage, the ostium of the left atrial appendage, and / or at least a portion of a tissue adjacent to the ostium of the left atrial appendage.

The application provides a method for fixing an interventional valve on a mitral valve, which comprises the following steps: driving a plurality of fixing nails into the left atrial side wall above the mitral valve; and connecting a fixing disc on the atrial septum through a connecting line to form a plurality of fixing lines above the mitral valve. The fixing method can form a plurality of fixing lines above the mitral valve, and the fixing lines can provide stable fixing support for the interventional valve implanted below, thereby effectively solving the problem that the current interventional mitral valve is difficult to be stably anchored, and the method for fixing the interventional valve on the mitral valve is simple and convenient to operate.

The subject of the invention is a left atrium appendage clamp consisting of two clamping jaws attached to a common elastic element in the form of at least one bow, which maintains them at a constant distance from each other and where said at least one bow constitutes a cut-out collar, each end of which is connected to a clamping jaw, characterized in that each of the clamping jaws (3) consists of a straight bow part (3a), which passes successively into a radius part (3b) with a bend (4) behind which the end of the jaw (3c) is located, wherein said bend (4) in the radius part (3b) constitutes a bend (4) at least along the first longitudinal axis (X) relative to the straight bow part (3a). Another subject of the invention is a dedicated applicator for attaching the clamp according to the invention and a set for closing and electrically insulating the left atrium appendage consisting of a left atrium appendage clamp according to the invention and an applicator according to the invention.

An ultrasound imaging system may receive ultrasound data of a heart, wherein the ultrasound data was acquired across at least a portion of a cardiac cycle of the heart. The ultrasound imaging system may generate strain measurements based, at least in part on the ultrasound data. The ultrasound imaging system may analyze, using a cardiotoxicity detection algorithm, at least the strain measurements to determine a cardiotoxicity level of the heart. In some examples, the cardiotoxicity detection algorithm comprises a support vector machine (SVM) model trained on one or more of left ventricular (LV) strain data, left atrial (LA) strain data, right ventricular (RV) strain data, or right atrial (RA) strain data. In some cases, the cardiotoxicity detection algorithm uses one or more global left ventricular (LV) strain curves as an input to determine the cardiotoxicity level of the heart.

The invention provides a left atrial appendage image measurement method and system, electronic equipment and a storage medium, and relates to the technical field of left atrial appendage image measurement. The image measurement method comprises the following steps: transforming three-dimensional heart image data according to a spatial position transformation relationship to determine transformed three-dimensional heart image data; transforming the transformed three-dimensional heart image data according to the left auricle motion change function to determine four-dimensional heart image data; and analyzing the four-dimensional heart image data based on a preset AI algorithm to determine a target dynamic parameter of the left auricle in the heartbeat cycle. Based on the spatial position transformation relation and the left auricle motion change function, the dynamic parameter change curve of the left auricle in the whole heartbeat cycle (including the systolic period and the diastolic period) is introduced, and dynamic change information of the left auricle form in the heartbeat cycle is provided, so that the image measurement of the left auricle is more reliable and stable, and the measurement accuracy is improved. And the measurement accuracy is improved.

The present teaching provides devices and methods for treating heart disease by normalizing elevated blood pressure in the left and right atria of a heart. Various embodiments of the devices allow left-to-right blood flow through their flow elements. The flow element of the device is designed to self-adjust the amount of blood flow in response to the left atrial pressure fluctuation.

The invention belongs to the technical field of medical data analysis, and particularly relates to a new atrial fibrillation risk prediction method and system for an ICD implantation patient, and the method comprises the steps: data acquisition: collecting clinical characteristic parameters of the ICD implantation patient, including gender, left atrium inner diameter, diabetes mellitus indexes and pulmonary artery systolic pressure; data preprocessing: carrying out binarization and standardization processing and classification variable coding; model construction: based on a multi-factor statistical analysis model, establishing a mathematical association equation of the clinical characteristic parameters and the new atrial fibrillation risk; risk calculation: calculating the risk probability of new onset atrial fibrillation of the individual according to the equation, and outputting a 0-1 risk value; and outputting a result, and generating a visual risk assessment result. According to the method, a multi-factor model is constructed to predict the risk of new atrial fibrillation after ICD implantation of sudden cardiac death high-risk population, AUC = 0.793 (95% CI is 0.705-0.855), and the method is a special prediction tool for ICD implantation population.

The present invention discloses a customization system for a left atrial appendage occluder, comprising an imaging module, a processing module, and a three-dimensional printer. The input end of the imaging module is connected to the output end of a detection device placed in the patient's heart, the output end of the imaging module is connected to the input end of the processing module, and the output end of the processing module is connected to the input end of the three-dimensional printer. The imaging module is used to perform three-dimensional imaging of the patient's heart by detecting cardiac electrophysiological signals with the aid of the detection device, thereby establishing a three-dimensional computer model of the patient's left atrium and left atrial appendage. The processing module is used to identify the characteristic parameters of the patient's left atrial appendage based on the three-dimensional computer model established by the imaging module, thereby determining the specification data of the left atrial appendage occluder. The three-dimensional printer is used to complete 3D printing according to the specification data of the left atrial appendage occluder. The present invention can provide patients with personalized customization services for left atrial appendage occluders quickly and effectively, and the customized left atrial appendage occluder has good adaptability and a high success rate of surgery.

The utility model discloses a plug type left auricle of heart stopper, including the plug body of net, one end of plug body is equipped with the first connecting piece for connecting positioning structure, the other end of plug body is equipped with the second connecting piece for connecting conveying instrument, be equipped with the stoppage film on plug body, the outer periphery of plug body is equipped with the anchoring structure. The plug type left auricle of heart stopper can cooperate with the positioning plug with the positioning plug as the support adjustment release position and angle, to obtain better stoppage effect, avoid turning over, improve the success rate of operation, simple operation, safe and reliable.

The utility model discloses a device for automatically executing a foaming test. In the application, the device is firstly switched to a left atrial radiography working mode, the device is switched to a first pipeline state, a second valve is communicated with a first container and a first injector, the second valve closes a pipeline between the first injector and a second injector, the first injector extracts radiography mixed liquid from the first container, and the first container is communicated with the second injector; then the device is switched to a second pipeline state, a second valve and a third valve are communicated with the first injector and the second injector, the second valve closes the pipeline between the first injector and the first container, the third valve closes the pipeline between the second injector and the second end, and at the moment, the first injector and the second injector push and inject radiography mixed liquid in a reciprocating mode; the contrast mixed liquid forms bubble liquid in the state of the second pipeline, so that the preparation of the left atrium contrast bubble liquid is automatically completed, and the preparation efficiency and the consistency of the prepared bubble liquid are improved.

The application discloses a left auricle plugging device distal end necking auxiliary device and a necking method, which comprises a base, a guide lining core, a guide sleeve, a first necking sleeve, a second necking sleeve and a mounting sleeve, an inner ring for supporting the inner periphery of a support rod of the left auricle plugging device is arranged on the first necking sleeve, a positioning ring for positioning the support rod is arranged on the second necking sleeve, and an outer ring for fixing the outer periphery of the support rod is arranged on the mounting sleeve; the inner ring, the positioning ring and the outer ring are in the same radial direction, and a positioning groove corresponding to the support rod is arranged on the positioning ring; the first necking sleeve, the second necking sleeve and the mounting sleeve are cooperated, the inner ring, the positioning ring and the outer ring are fixed, the necking device is not limited by the structure of the left auricle plugging device, has universality, and the assembly mode that pipelines are directly sleeved can simplify operation steps and improve necking efficiency.

In vivo visualization systems are described which facilitate tissue treatment by a user in utilizing real time visualized tissue images with generated three-dimensional models of the tissue region of interest, such as the left atrial chamber of a subject's heart. Directional indicators on the visualized tissue as well as the imaging systems may be utilized while other variations may utilize image rotation or manipulation of visualized tissue regions to facilitate catheter control. Moreover, visualized tissue regions may be combined with imaged tissue regions as well as navigational information to further facilitate tissue treatments.

The invention discloses a left atrium sensing implantation device based on piezoelectric ceramic ultrasonic energy supply and a sensing system. The left atrium sensing implantation device comprises a shell, piezoelectric ceramic, a sensor and a transceiving circuit. The piezoelectric ceramic adopts a partition electrode design, a concentric annular region of the piezoelectric ceramic is used for receiving in-vitro ultrasonic energy and converting the in-vitro ultrasonic energy into electric energy, and a fan-shaped region of the piezoelectric ceramic is used for modulating sensing data in a load keying (LSK) mode and backscattering the sensing data. The sensor is integrated based on a CMOS-MEMS process and synchronously collects pressure and temperature signals in the left atrium. The system further comprises an in-vitro ultrasonic probe and a host, and wireless energy supply, data return and information display are achieved. Complete wireless passive work and minimally invasive implantation of the implantation device are achieved, high-precision and continuous real-time monitoring of pressure and temperature of the left atrium is supported, and the device is suitable for long-term physiological parameter management of heart failure patients.

The invention provides a key target potential identification method in atrial fibrillation catheter radiofrequency ablation, which comprises the following steps of: in an atrial fibrillation state, reconstructing anatomical shells of a left atrium (LA) and a right atrium (RA) through a system, performing two-stage electrogram acquisition by adopting a catheter, and marking a KSPs region on a three-dimensional anatomical model; performing point-by-point ablation on the marked KSPs area; after the key superimposed potential (KSPs) is ablated, the globally disordered atrial electrical activity tends to be ordered; if atrial fibrillation is converted into regular atrial velocity (AT), the AT is regarded as an atrial fibrillation driving focus, and excitation mapping and ablation need to be further carried out until sinus rhythm is recovered; after the sinus rhythm is recovered, burst pacing stimulation is carried out again through the coronary sinus catheter, and the non-inductivity of the atrial fibrillation is verified; and if the atrial fibrillation still can be induced, repeating the steps a, b and c, and searching and ablating the residual KSPs until the atrial fibrillation cannot be induced. The KSP identification and ablation method provided by the invention is remarkably improved in the aspects of mechanism understanding, mapping means, ablation strategies and clinical outcome.

Implantable occlusion devices that include one or more flanges extending from a tubular body are disclosed. The flange or flanges may assist in retention of the device within a vessel, cavity, appendage, etc. At least one flange on the occlusion device may include a concave surface proximate one end of a body. Because of the shape of the flange, e.g., its concavity, the occlusion device may resist dislocation due to e.g., the forces generated within the left atrial appendage during atrial fibrillation.

The engagement of the two atria via atrial pacing therapy is determined using one or more metrics based on monitored external electrical activity. For example, external electrical activity can be monitored during delivery of the atrial pacing therapy, right atrial and left atrial components can be generated based on the monitored external electrical activity, and one or more metrics can be generated based on the right atrial and left atrial components. One or more metrics can then be used to determine whether the atrial pacing therapy has biatrial engagement.