31 results about "Heart Auricles" patented technology

The invention discloses a CCTA image-based left auricle filling defect automatic segmentation and classification method, which realizes automatic identification and segmentation of left auricle thrombus, and comprises the following steps: S1, data acquisition and preprocessing; step S21, segmenting and sketching the image; step S22, training a deep learning neural network model by using the three-dimensional region of interest obtained in the step S21; s3, verifying the deep learning neural network model in the step S22 by using an external verification set; step S41, feature extraction; step S42, constructing a classification model; and S5, verifying the classification effect and explaining the classification effect, through the method, compared with previous manual segmentation sketching, a large amount of time and manpower resources are saved, through the method, image features, radiomics features and deep learning features can be combined, and compared with previous independent radiomics feature modeling, multiple artificial intelligence methods are integrated, so that the modeling efficiency is improved. And a more accurate diagnosis model is constructed.

A prosthetic aortic valve that uses actuating arms and grippers to attach to leaflets, reducing device migration and sizing issues. It involves excising diseased leaflets prior to implantation, ensuring blood flow to coronary arteries, and offers optical visualization. The valve features replaceable leaflets and a streamlined frame. Innovative left atrial appendage devices, embolic protection devices, intra-cardiac echocardiography devices, and steerable catheter devices are introduced. Provided herein are atraumatic, cinchable mitral valve annular repair devices, noninvasive methods that modify body calcium with electromagnetic energy, and systems for optical visualization in vascular interventions by displacing blood with clear fluid.

The invention provides an atrial appendage clamp and a ligation system. The auricle clamp comprises a transmission assembly and a clamping assembly. The clamping assembly is installed at the far end of the transmission assembly and comprises a clamping jaw and two clamping pieces. The side, facing the other clamping piece, of each clamping piece is provided with a clamping face, and the clamping face comprises a plurality of protrusions arranged at intervals. When the transmission assembly moves, the clamping jaws are linked to conduct clamping, so that the multiple protrusions on each clamping face abut against the multiple protrusions on the other clamping face in a one-to-one mode. By means of the design that the protrusions on the clamping faces abut against each other correspondingly in the clamping state, the clamping stability can be guaranteed on the premise that auricle tissue is protected from being damaged by clamping, and the left auricle ligation clamp is suitable for the scene of an interventional left auricle ligation operation.

Disclosed herein are devices and methods for addressing elevated left-sided filling pressures to mitigate the effects of diastolic dysfunction. The disclosed technologies decrease the temporal increase in blood flow and pressure into the heart from the venous system (which drains from the body). Under exertion, there is a shift of blood from the 'unstressed' reservoir of vasculature to the 'stressed' reservoir. By inhibiting this acute shift of blood from the unstressed reservoir to the stressed reservoir, an undesirable influx of blood volume to the already overloaded left heart can be avoided. Certain embodiments provide ways to maintain or to increase atrial elasticity, or atrial compliance using devices implanted in the left atrium and / or left atrial appendage. This increase or enhancement of atrial compliance enables the atrium to absorb the energy of short bursts of high left atrial pressure.

The invention relates to an auricular appendage clip conveying handle and an auricular appendage clip conveyor with the auricular appendage clip conveying handle, and the auricular appendage clip conveying handle comprises a shell and an adjusting assembly. The adjusting assembly is arranged at the position, close to the handle part, of the shell body, a user can conduct unlocking, direction adjusting and locking operation through simple pushing and pressing, the convenience of the auricular appendage clip conveying handle is improved, the operation efficiency is improved, the operation progress is accelerated, and the operation risk is reduced. The auricular appendage clip conveying handle effectively solves the problems that in the prior art, due to the fact that the position of an auricular appendage clip needs to be adjusted in the implanting process, the auricular appendage clip conveying handle needs to be independently provided with a position adjusting structure and a limiting structure of the auricular appendage clip, and the adjusting program of the auricular appendage clip is strictly controlled, the auricular appendage clip conveying handle is not convenient to use, and the operation process is affected.

A method of treating a tissue of the heart, for example and without limitation, a tissue of the left atrial appendage, includes twisting at least a portion of a tissue of the left atrial appendage to constrict an ostium of the left atrial appendage, and ablating at least a portion of the tissue of the heart, which can include a tissue of the left atrial appendage, the ostium of the left atrial appendage, and / or at least a portion of a tissue adjacent to the ostium of the left atrial appendage.

An occluder (100) to occlude an appendage opening or a coronary hole includes a first end region (102) having a first end diameter, a convex-shaped first upper side (115), and a first lower side (116). The occluder (100) also includes a second end region (104) having a second diameter, a second upper side (117), and a convex-shaped second lower side (118). The occluder (100) further includes a waist (106) having a waist diameter that is smaller than the first end diameter and the second end diameter. The first lower side (116) and the second upper side (117) meet at the waist.

The utility model discloses an automatic rebound conveying actuator of a clip applier and an auricular appendage clip conveyor. The actuator comprises a body device with one end provided with a control area; the clamping device is arranged at the other end of the body device and comprises a first clamping arm assembly and a second clamping arm assembly which are used for clamping an object to be placed; the elastic device is arranged on the clamping device and has pre-tightening resultant force in an assembling state; when the clamping device is completely separated from the object to be placed, the first clamping arm assembly and the second clamping arm assembly move mutually under the action of pre-tightening resultant force to form a closed and attached whole. According to the scheme, automatic closing of the clamping arms can be achieved after the clamping arms are completely separated from a to-be-implanted object, the size of the formed closed and attached whole is smaller than the size of the to-be-implanted object in the clamping state, it is guaranteed that the closed and attached whole is stabilized at the minimum size, damage to human tissue is effectively reduced, the surgical operation difficulty is reduced, the surgical risk is reduced, and the surgical time is shortened.

The application provides a heart tissue closing device, and relates to the field of medical instruments.The heart tissue closing device comprises a first clamping arm, a second clamping arm and a locking part, the first clamping arm comprises a first end and a second end, the second clamping arm comprises a first end and a second end, the first clamping arm and the second clamping arm can rotate around the first ends of the two to realize opening and closing of the second end of the first clamping arm and the second end of the second clamping arm, and the locking part acts on the first clamping arm and the second clamping arm to prevent the first clamping arm and the second clamping arm from opening.The heart tissue closing device of the application realizes the closing of heart tissue through the clamping of the first clamping arm and the second clamping arm, and keeps the first clamping arm and the second clamping arm in the closed state through the locking part, the V-shaped opening structure breaks through the limitation of the ligation mode, does not need to be sleeved from the top end of the auricle, the opening clamping arm is inserted along the root of the auricle to be closed, and the closing operation is more convenient to be implemented at the root of the auricle from various angles.

The invention provides a left atrial appendage image measurement method and system, electronic equipment and a storage medium, and relates to the technical field of left atrial appendage image measurement. The image measurement method comprises the following steps: transforming three-dimensional heart image data according to a spatial position transformation relationship to determine transformed three-dimensional heart image data; transforming the transformed three-dimensional heart image data according to the left auricle motion change function to determine four-dimensional heart image data; and analyzing the four-dimensional heart image data based on a preset AI algorithm to determine a target dynamic parameter of the left auricle in the heartbeat cycle. Based on the spatial position transformation relation and the left auricle motion change function, the dynamic parameter change curve of the left auricle in the whole heartbeat cycle (including the systolic period and the diastolic period) is introduced, and dynamic change information of the left auricle form in the heartbeat cycle is provided, so that the image measurement of the left auricle is more reliable and stable, and the measurement accuracy is improved. And the measurement accuracy is improved.

The present invention discloses a customization system for a left atrial appendage occluder, comprising an imaging module, a processing module, and a three-dimensional printer. The input end of the imaging module is connected to the output end of a detection device placed in the patient's heart, the output end of the imaging module is connected to the input end of the processing module, and the output end of the processing module is connected to the input end of the three-dimensional printer. The imaging module is used to perform three-dimensional imaging of the patient's heart by detecting cardiac electrophysiological signals with the aid of the detection device, thereby establishing a three-dimensional computer model of the patient's left atrium and left atrial appendage. The processing module is used to identify the characteristic parameters of the patient's left atrial appendage based on the three-dimensional computer model established by the imaging module, thereby determining the specification data of the left atrial appendage occluder. The three-dimensional printer is used to complete 3D printing according to the specification data of the left atrial appendage occluder. The present invention can provide patients with personalized customization services for left atrial appendage occluders quickly and effectively, and the customized left atrial appendage occluder has good adaptability and a high success rate of surgery.

The utility model discloses a plug type left auricle of heart stopper, including the plug body of net, one end of plug body is equipped with the first connecting piece for connecting positioning structure, the other end of plug body is equipped with the second connecting piece for connecting conveying instrument, be equipped with the stoppage film on plug body, the outer periphery of plug body is equipped with the anchoring structure. The plug type left auricle of heart stopper can cooperate with the positioning plug with the positioning plug as the support adjustment release position and angle, to obtain better stoppage effect, avoid turning over, improve the success rate of operation, simple operation, safe and reliable.

The valve implant and vascular closure device of this article are configured to be positioned in the heart and block the blood of backflow from the heart into the blood vessels that supply blood to the heart. The valve implant may have a cover, a film, a valve, an elastic frame and / or other features. Some valve implants may have anchors positioned in blood vessels, such as in the pulmonary veins, and the implant may be anchored to the heart wall. Various embodiments of the cover and / or film act as valves that contract and expand to alternately allow and block blood flow. The valve implant may cover one or more blood vessels, such as one, two, three or four pulmonary veins, and may also be configured and implanted to block the appendages of the heart, such as the left atrial appendage.

The present invention discloses a left atrial appendage ligator in the technical field of medical equipment, which comprises a ligature and an operating handle, a support part fixedly connected to one end of the operating handle, a supply tube and a lock tube fixedly connected to the inner wall of the support part, a first slide groove formed in the inner wall of the supply tube, a first slide block slidably connected to the inner wall of the first slide groove, a supply push rod fixedly connected to the middle part of the first slide block, a first hook fixedly connected to one end of the supply push rod, and a return spring fixedly connected to one side of the first slide block. In this left atrial appendage ligator, a locking push rod, a ligature, a hanging knot and a support assembly are provided, and the ligature is pre-installed in the sleeve portion to form the hanging knot, thereby avoiding the need to tie the knot during surgery and allowing the knot to be tied simply by locking the hanging knot during surgery. The sleeve portion is used as a support member for passing the other end of the ligature to avoid automatic locking, and when the sleeve portion is released from the hanging knot, the hanging knot can be pulled and automatically locked, thereby shortening the surgical time and improving the surgical efficiency.

The application provides a heart tissue closure device. The device comprises a first clamping arm, a second clamping arm and an elastic member. One end of the first clamping arm is rotatably connected to one end of the second clamping arm, and the elastic member provides clamping force for the first clamping arm and the second clamping arm. The heart tissue closure device of the application provides clamping force through the elastic member, which is applied to the outside of the first clamping arm and the second clamping arm, so as to drive the clamping arms to flatten the inside auricle, realize the closure of the auricle, and prevent the auricle from being folded during ligation. The device can continuously provide stable clamping force through the elastic member, so as to ensure that the auricle can be completely closed when the thickness of the auricle is reduced. The device is wrapped by multiple layers, the contact area is increased, and the risk of tearing the heart tissue during clamping is prevented.

The invention discloses a plugging device, and relates to the technical field of medical instruments. The plugging device comprises a plugging body, an elastic connecting piece and a hanging part, the plugging body is suitable for being matched with the shape of a target plugging area; one end of the elastic connecting piece is arranged on the plugging body; one end of the hanging part is connected with the other end of the elastic connecting piece, and the hanging part is suitable for being hung on the tissue of the target plugging area. The plugging device which is made of degradable materials and is made for the cauliflower-shaped left auricle can be implanted into the left auricle of a patient through minimally invasive catheter interventional operation to plug the left auricle, climbing and covering of endothelial tissue of a left atrium are guided, then complete degradation of an instrument in a human body after endothelialization is achieved, and the left auricle plugging effect is achieved. And finally, the plugging effect is completely realized by the autologous tissue of the patient, the formation and falling of thrombus emboli in the left atrial appendage are effectively prevented, and the occurrence risk of cerebral apoplexy diseases is greatly reduced.

The invention discloses a circulating perfusion method which comprises the following steps: after a perfusion needle head is inserted into an artificial heart, the perfusion needle is connected to a perfusion pump through a perfusion tube, the other end of the perfusion tube is immersed below the liquid level of perfusion liquid, a double-channel circulating design is adopted, the solution is perfused from the artificial heart to a vasculature, and the solution flowing out of an auricle is collected. The coloring agent and the embedding medium are ensured to be uniformly distributed in the whole body, the permeation efficiency is improved, and the permeation uniformity index of a circulating perfusion group is remarkably superior to that of a passive diffusion method. By optimizing decalcification and degreasing, the fluorescence intensity retention rate gt of the sample is obtained; 80%. By adopting an MAA / NMA hydrogel system, polymerization is completed at 40 DEG C for 4 hours, so that the treatment period is greatly shortened, the treatment efficiency is improved, and rapid hydrogel embedding is realized. The Lange peristaltic pump is adopted to realize stable flow speed, and a temperature control system is combined, so that tissue damage is avoided. And finally, three-dimensional reconstruction of the whole tissue is realized.

A plugging device comprises a plugging piece and a covering piece, the plugging piece comprises a first net body and a first collecting element, and the near end of the first net body is collected in the first collecting element; the covering part comprises a second net body, a second collecting element and a third collecting element, the far end of the second net body is collected in the second collecting element, and the near end of the second net body is collected in the third collecting element. Wherein the first collecting element is suitable for being in butt joint with the second collecting element, and medical staff can select to independently use the plugging piece or select the proper plugging piece and the covering piece to be used in a matched mode according to the shape of the left auricle of a patient. Besides, a limiting structure is arranged at the connecting position of the first collecting element and the second collecting element, the first collecting element and the second collecting element can be prevented from being separated, and therefore the risk of connection failure of the plugging piece and the covering piece is eliminated in the conveying or implanting process of the plugging device or after the plugging device is implanted, and the operation quality safety is improved.

The application discloses a kind of for left auricle plugging operation navigation multi-modal image automatic registration method, comprising the following steps: collecting structural heart disease intervention surgery patient preoperative CTA image and intraoperative CBCT image;Using U-Net deep learning framework, the heart region in CTA image and CBCT image is segmented and extracted, and the extracted image region is carried out data enhancement and size normalization etc.Pretreatment operation;With the network of depth convolution and visual Transformer fusion, the heart region image of CTA and CBCT is calculated Affine transformation matrix, so that the CTA image and CBCT image realize 3D affine registration;The image after registration is filled to the cutting region of the CBCT image, and the intraoperative CBCT image containing heart anatomical structure information is generated.The method of the application can realize the automatic, fast and accurate spatial registration of preoperative CTA image and intraoperative CBCT image, and the fusion image view generated by registration provides comprehensive reference for the heart three-dimensional anatomical structure and real-time instrument position, effectively assists instrument positioning, path planning and size selection, and provides a new intelligent tool for left auricle plugging operation navigation.

A tissue stabilization device and method for stabilizing and optionally closing a target tissue such as a left atrial appendage generally comprises an elongated body having a first lumen and a second lumen, a suction tip coupled to the elongated body, and an injection tip coupled to the elongated body proximal to the suction tip. The suction tip may define a suction aperture, and the suction aperture may be in fluid communication with the first lumen to apply suction to the target tissue. The injection tip may be in fluid communication with the second lumen to dispense contrast fluid.

A system for implanting two or more implants into a heart of a patient may include a multi-device steerable guide catheter ("MDSGC"), a transcatheter edge-to-edge repair ("TEER") implant delivery device, and an additional implant delivery device for implanting an additional medical device. The additional medical device may be a collapsible and expandable prosthetic transcatheter aortic valve repair ("TAVR") device or a collapsible and expandable left atrial appendage ("LAA") occluder device. The MDSGC may have a first handle and may be steerable, the TEER delivery device may have a second handle, and the additional delivery device may have an additional handle. The system may include a fixation device to capture native heart valve leaflets therebetween as part of a TEER procedure. The TEER delivery device and the additional delivery device may each have a catheter sized and shaped to pass through an interior of a catheter of the MDSGC.

The invention discloses an automatic springback conveying actuator of a clip applier, an assembling method of the automatic springback conveying actuator and an auricular appendage clip conveyor. The actuator comprises a body device with one end provided with a control area; the clamping device is arranged at the other end of the body device and comprises a first clamping arm assembly and a second clamping arm assembly which are used for clamping an object to be placed; the elastic device is arranged on the clamping device and has pre-tightening resultant force in an assembling state; when the clamping device is completely separated from the object to be placed, the first clamping arm assembly and the second clamping arm assembly move mutually under the action of pre-tightening resultant force to form a closed and attached whole. According to the scheme, automatic closing of the clamping arms can be achieved after the clamping arms are completely separated from a to-be-implanted object, the size of the formed closed and attached whole is smaller than the size of the to-be-implanted object in the clamping state, it is guaranteed that the closed and attached whole is stabilized at the minimum size, damage to human tissue is effectively reduced, the surgical operation difficulty is reduced, the surgical risk is reduced, and the surgical time is shortened.

The present disclosure provides a solution for assisting cardiac circulation of a subject. In one aspect of the present disclosure, the new solution replaces the common practice of implementing a cannula of left ventricular assist device (LVAD) to the left ventricle (LV) through a large opening made in the apex of the LV, which has some disadvantages such as requirement of sternotomy, making a hole in an already very weak left ventricle, requirement of cardiopulmonary bypass, etc.The solution of the present disclosure suggests introducing the inflow cannula, namely the cannula / tube that suctions blood from the heart, through an opening made in the left atrium appendage (LAA) and guiding it through the left atrium (LA) and the mitral valve (MV) into the LV to be positioned therein. The inflow cannula is designed to allow suction of blood along various portions of its length that are intended to be positioned within the heart, namely along portions that are positioned in the LV, LA and optionally the LAA.The blood that is suctioned by the inflow cannula flows into a mechanical circulatory support device to be pumped therefrom, via an outflow cannula and into the aorta, thereby allowing supply of oxygenated blood to the entire body. Optionally, the outflow cannula can be coupled to the descending aorta and not to the ascending aorta as commonly done in the cases of LVAD implementations.A second aspect of the present disclosure provides a new solution for overcoming right ventricle failure by withdrawing blood from a first portion of the pulmonary artery and streaming blood to a second portion of the pulmonary artery, the second portion is downstream the first portion, namely more proximal to the lungs. The two solutions may be carried out by a similar surgical procedure, such as left thoracotomy. If the two solutions of the present disclosure are used together, they form a total artificial heart solution.

The utility model relates to the technical field of medical instruments, and discloses a plugging device which mainly comprises a first supporting net capable of shrinking in the radial direction. When the supporting net is in a natural state, the peripheral face of the middle of the supporting net is bent outwards to form a main body cambered surface outline adaptive to the outline of the left auricle, and the end faces of the two sides of the supporting net are bent inwards to form end cambered surface outlines, so that the plugging device is matched with a left auricle opening more easily in the implanting process, the problem that the plugging device is prone to displacement is effectively solved, and the plugging effect is improved. The safety and the success rate of the operation are improved; meanwhile, the end cambered surface outline of the near end of the first supporting net is gradually smooth in the implanting process to form a roughly planar structure, obvious protruding or sinking is avoided, the first supporting net can be smoothly connected with the inner wall of the implanting position, and the possibility of generating instrument-related thrombus is reduced.

The present invention relates to assessing the state of a mitral valve. In order to provide a facilitated way of assessing a pressure-related condition of a mitral valve, a device (10) for determining a pressure-related value of a mitral valve of a heart is provided that comprises a data input (12), a data processor (14) and an output interface (16). The data input is configured to provide a first ultrasound image (20) of a heart comprising at least a proximal part of a left atrial appendage of the heart in a first state; and to provide a second ultrasound image (22) of a heart comprising at least the proximal part of the left atrial appendage of the heart in a second state. The first state relates to a first pressure state of the left atrium of the heart and the second state relates to a second pressure state of the left atrium of the heart which second pressure state is different than the first pressure state. The data processor is configured to segment the first ultrasound image generating a first segmentation of at least a part of the left atrial appendage; and to segment the second ultrasound image generating a second segmentation of at least a part of the left atrial appendage; to determine, from the first segmentation, at least one first anatomical measurement relating to the left atrial appendage; and to determine, from the second segmentation, at least one second anatomical measurement relating to the left atrial appendage; and to derive at least one relation of the at least one first anatomical measurement and the at least one second anatomical measurement. The output interface is configured to provide the derived at least one relation as an indicator for a pressure related parameter of the mitral valve.

The invention provides a heart tissue closing device, and relates to the field of medical instruments. Comprising a first clamping arm, a second clamping arm and a locking part, and the first clamping arm comprises a first end part and a second end part; the second clamping arm comprises a first end part and a second end part, and the first clamping arm and the second clamping arm can rotate around the first end parts of the first clamping arm and the second clamping arm so as to realize opening and closing of the second end part of the first clamping arm and the second end part of the second clamping arm; the locking part acts on the first clamping arm and the second clamping arm so as to prevent the first clamping arm and the second clamping arm from being opened. According to the heart tissue closing device, the heart tissue is closed through clamping of the first clamping arm and the second clamping arm, the first clamping arm and the second clamping arm which are in a closed state are kept through the locking part, the limitation of a loop ligature mode is broken through through a V-shaped opening structure, sleeving from the top end of an auricle is not needed, and the heart tissue is closed. And the clamping arms are opened to be inserted along the root of the auricle for closing, so that the closing operation can be more conveniently implemented at the root of the auricle from various angles.

The invention provides a heart tissue closing device, and relates to the field of medical instruments. The device comprises a first clamping arm, a second clamping arm and an elastic piece, one end of the first clamping arm is rotationally connected with one end of the second clamping arm, and the elastic piece provides clamping force for the first clamping arm and the second clamping arm. According to the heart tissue closing device, clamping force is provided through the elastic piece and applied to the outer sides of the first clamping arm and the second clamping arm, so that the clamping arms are driven to flatten the auricles on the inner sides, the auricles are closed, and the central auricles can be prevented from being folded in the ligation process; the device can continuously apply stable clamping force through the elastic piece, so that the atrial appendage can still be completely closed when the atrophy thickness is reduced. According to the device, through multi-layer wrapping, the contact area is increased, and the tearing risk of heart tissue in the clamping process is prevented.