19 results about "Autologous tissue" patented technology

The present invention relates to a mould (1), the mould comprising a receptacle (10) and a lid (20) for forming a tissue graft, such as an autologous tissue graft for transplant and suturing. The mould is adapted to contain layers of biological material, providing pressure to the biological material and drain out excess fluid, thus providing a fast and effective means for building a tissue graft. The mould may comprise one or more resilient members, and at least one or more of the resilient members (RM) may be suitable to provide a specified force to apply the desired pressure to the tissue graft. The invention further relates to a method of using the mould.

The application discloses a plugging device and relates to the technical field of medical devices. The plugging device comprises a plugging body, an elastic connecting piece and a hanging component. The plugging body is adapted to the shape of a target plugging area. One end of the elastic connecting piece is arranged on the plugging body. One end of the hanging component is connected with the other end of the elastic connecting piece, and the hanging component is adapted to be hung on the tissue of the target plugging area. The plugging device for cauliflower-shaped left atrial appendages is made of degradable materials, can be implanted into the left atrial appendages of a patient through a minimally invasive catheter intervention operation to realize plugging of the left atrial appendages, can guide the climbing of the endothelial tissue in the left atrium, and can realize complete degradation of the device in the human body after endothelialization. Finally, the plugging effect is realized by the patient's autologous tissue, the formation and shedding of thrombus embolus in the left atrial appendages are effectively prevented, and the risk of stroke is greatly reduced.

The invention provides an autologous tissue filler for static texture repair and a preparation method of the autologous tissue filler, and relates to the technical field of biological tissue filling. The filler provided by the invention comprises autologous blood cells, autologous hair follicle protrusion parts and hair follicle tissues homologous with the autologous hair follicle protrusion parts, wherein the hair follicle tissues are residual parts of autologous hair follicles after the protrusion parts are separated and surrounding tissues. The filler provided by the invention not only can effectively repair facial static lines and is compatible with dermis tissues of the static lines, but also cannot generate rejection reaction, and in addition, the filler can be regenerated and cannot be absorbed and shrunk, so that the filling effect can be effectively maintained.

The present invention relates to a mould (1) for forming a tissue graft, preferably an autologous tissue graft for transplantation and suturing. The mould comprises a receptacle (10) and a pressure plate (30). The mould is adapted to contain layers of biological material, providing pressure to the biological material and drain out excess fluid, thus providing a fast and effective means for building a tissue graft. The receptacle (30) is adapted with a mass m, the mass adjusted to provide the specific pressure, relative to the area of a bottom surface (11) of the receptacle, wherein the tissue graft is to be manufactured. In some embodiments, the mould may further be provided with a weighted element, the weighted element adapted with a mass correlating to an area of the receptacle, thus providing a specific amount of force and thus pressure to the biological material arranged in the mould during use.

The invention provides a breast augmentation method and method.The method comprises the steps that firstly, a shape memory biopolymer material with biological absorbability is selected, and a filling device with a preset three-dimensional configuration is formed through a weaving technology or a 3D printing technology; 2, the filling device is conveyed to the posterior gap of the breast through an endoscope channel or a conveying catheter or directly through a surgical incision and is released, and friction fixation with surrounding tissue is achieved through the radial supporting force of the filling device; 3, after the filling device is stably anchored in the posterior gap of the breast, attachment is completed by means of biocompatibility of the filling device, and surface autologous tissue growth is achieved. According to the method, the filling device is gradually degraded and absorbed by human tissues, only few polymer wire binding points are left finally, an autologous tissue filling structure is formed in the breast, the full, natural, lasting and stable breast augmentation effect is achieved, and the technical problems that autologous fat breast augmentation is easy to absorb, and a silica gel prosthesis is not natural in hand feeling are effectively solved.

Medical systems, devices and methods for creation of autologous tissue valves within a mammalian body are disclosed. One example of a device for creating a valve flap from a vessel wall includes an elongate tubular structure having a proximal portion and a distal portion and a longitudinal axis; a first lumen having a first exit port located on the distal portion of the elongate tubular structure; a second lumen having a second exit port located on the distal portion of the elongate tubular structure; a recessed distal surface on the distal portion of the elongate tubular structure, wherein the recessed distal surface is located distally to the first exit port; and an open trough on the recessed distal surface extending longitudinally from the first exit port.

A 3D printed degradable chest rib implant comprises a main body and a fixing port arranged on the main body, wherein the curvature of the main body is consistent with the curvature of a rib defect; the main body has a multi-layer structure, the inner layer is a mechanical support-bone fusion structure to provide initial strength required for maintaining the shape of the thoracic structure and respiratory expansion and space for growth of new bone tissue, and the outer layer is a porous structure to facilitate the growth of surrounding soft tissue and later biological fusion fixation; the fixing port on the main body is installed and fixed with a corresponding chest rib combination site; through the regulation of the degradable material components and macro-micro structure, the function of the degradable chest rib implant is programmed to realize the dynamic matching and transformation of mechanical stability and tissue regeneration, with the degradation of the degradable chest rib implant material, the autologous tissue gradually grows into and completely replaces the degradable chest rib implant; the present application can adapt to the repair requirements of congenital chest rib defects in children.

The degradable stent is of a hollow tubular structure with the two ends open and comprises a main tube body and retention flanges at the two ends of the main tube body, the main tube body comprises a plurality of coaxially-nested sub-tube bodies, annular gaps are formed between the adjacent sub-tube bodies, the two ends of any sub-tube body are connected with the retention flanges, and a plurality of holes are formed in the tube wall of each sub-tube body; and in the radial direction of the main pipe body, the porosity of the pipe wall of the sub pipe body is gradually increased from the central axis to the periphery. The main tube body is arranged to be a plurality of coaxially nested sub-tube bodies with gradually increased porosity, an outer-layer tissue migration guiding channel is formed, the sub-tube bodies on the outermost layer of the stent preferentially induce rapid migration and colonization of autologous tissues, and a gradual mechanical supporting environment is provided for deep tissue cell ingrowth along with the sequential reduction of the porosity of the inner layer. When autologous cells construct a complete cavity tissue structure, each layer of material of the stent is gradually degraded and absorbed according to a preset gradient, and finally a natural cavity with a physiological function is formed at an implantation part, so that the risk of a secondary operation is avoided.

Embodiments disclosed herein relate to devices and methods for autologous tissue transfer for a subject. In some embodiments, a syringe may include a barrel and an outlet as well as a primary plunger and a secondary plunger disposed at least partially within the barrel. The primary plunger may be transitioned between a closed configuration and an open configuration to permit fluid communication between a primary chamber and a secondary chamber located within the internal volume of the barrel. The user may employ the embodiments of such a device to extract adipose, or other desired, tissue from a subject into the primary chamber. In some embodiments, extracted adipose tissue may be separated into density-based layers of fat graft and waste products. The waste products may be isolated in the secondary chamber while retaining the fat graft in the primary chamber such that the fat graft may be re-administered to the subject.

The invention belongs to the field of intelligent medical treatment, and particularly relates to a system for treating SUI through transvaginal urethra middle section parapubis ligament linear suspension. The system comprises: a positioning dissection treatment unit 101, which is used for longitudinally cutting the vagina anterior wall mucous membrane along the median line of the vagina anterior wall to a set depth under the urethral transverse sulcus; the separation and exposure treatment unit 102 is used for separating the bladder from the vaginal wall, then separating the left / right gap of the bladder to obtain free fascia beside the middle section of the left / right urethra, and exposing the left / right pubis descending lateral ligament; and the suspension treatment unit 103 is used for respectively lifting fascia beside the middle section of the left / right urethra to a left / right pubis descending lateral ligament obliquely above the urethra for suturing and fixing. The inverted splayed linear seam of the fascia tissue beside the middle section of the urethra is hung to the ligament beside the pubis, meanwhile, the sutures on the two sides do not intersect at the middle line of the urethra, the included angle between the urethra and the bladder is recovered from the anatomy of the autologous tissue, the risks of mesh erosion, exposure and the like are avoided, and postoperative urethra obstruction and urinary retention are reduced.

The present invention relates to a human body-implantable structure for urethral compression and a composition for treating urinary incontinence comprising same. The structure of the present invention does not require a separate removal procedure due to the biocompatibility and biodegradability of a central main body implanted in the human body, can be replaced with autologous tissue without adhesion problems to thereby continuously compress the urethra, and has excellent durability without structural deformation even during thermal shrinkage of a shrinkable tube surrounding a connection portion between lifting threads, due to the heat resistance of a side mesh that connects the lifting threads and the central main body. In addition, the mesh included in the structure of the present invention is manufactured by weaving polymer yarns such that the course direction alternates front-to-back, thereby generating uniform resistance in all directions when inserted into the human body, which enables the structure to be smoothly inserted and be seated without curling in one direction.

The application belongs to the field of intelligent medical treatment and particularly relates to a system for treating SUI through transvaginal urethral middle segment pubic paravaginal ligament linear suspension. The system comprises: a positioning and dissection processing unit (101) for incising the mucosa of the anterior vaginal wall along the longitudinal line of the anterior vaginal wall to a set depth reaching the urethral transverse groove; a separation and exposure processing unit (102) for separating the bladder from the vaginal wall, then separating the left / right side space of the bladder to obtain the free left / right side urethral middle segment paravaginal fascia and expose the left / right side pubic ramus lateral ligament; and a suspension processing unit (103) for respectively lifting the left / right side urethral middle segment paravaginal fascia to the left / right side pubic ramus lateral ligament obliquely above and suturing and fixing. The application linearly sutures and suspends the urethral middle segment paravaginal fascia tissue in a reverse V shape on the pubic paravaginal ligament, and the sutures on the left and right sides do not cross at the urethral midline, which not only anatomically recovers the urethra and bladder angle with autologous tissue, avoids the risk of mesh erosion and exposure, but also reduces the incidence of postoperative urethral obstruction and urinary retention.

The invention discloses a bionic rhinoplasty stent, and relates to the technical field of rhinoplasty, the rhinoplasty stent comprises a nasal columella area and a nasal septum clamping area connected with the nasal columella area, and the nasal columella area is located in front of the nasal septum clamping area; the columella nasi area comprises a columella nasi main body, the left side and the right side of the columella nasi main body are both connected with outer side foot supporting parts, the columella nasi main body and the outer side foot supporting parts are of an integrated structure, and the nasal septum clamping area comprises two nasal septum clamping pieces connected with the columella nasi main body; the nasal columella main body and the outer side foot supporting part are integrally arranged, so that the rhinoplasty stent does not need to be set up and sutured, an autologous tissue does not need to be additionally used for nose tip heightening, suturing and fixing, the stent can be directly adopted, the rhinoplasty difficulty is reduced, the time needed by rhinoplasty is shortened, and the rhinoplasty efficiency is improved. The problems that due to the fact that the outer side foot support and the fornix supporting portion support are sutured respectively, the nose tip portion is loosened and displaced, the nose tip rotates up and down, and the beauty seeker needs to be operated again are solved, and the pain of the beauty seeker in the rhinoplasty operation is relieved.

Disclosed in the present invention is a bionic rhinoplasty stent, relating to the technical field of rhinoplasties. The rhinoplasty stent comprises a nasal columella area and a nasal septum clamping area connected to the nasal columella area. The nasal columella area is located in front of the nasal septum clamping area. The nasal columella area comprises a nasal columella body. The left and right sides of the nasal columella body are connected to outer side foot supporting parts. The nasal columella body and the outer side foot supporting parts are of an integrated structure. The nasal septum clamping area comprises two nasal septum clamping pieces connected to the nasal columella body. According to the present invention, the nasal columella body and the outer side foot supporting parts are integrally arranged, and without construction and suturing of the rhinoplasty stent, and without additional autologous tissue for elevating and suture fixing of the nasal tip, the stent of the present application can be directly adopted, thus reducing the difficulty of the rhinoplasty, shortening the time required by the rhinoplasty, and avoiding the problem of the need for another surgery for those who seek beauty due to loosening and displacement of the nasal lobule, or upward / downward rotation of the nasal tip caused by separate suturing of an outer side foot stent and a dome supporting part stent. Therefore, the pain of those who seek beauty during rhinoplasty is reduced.

The invention belongs to the technical field of far-infrared active cotton, and particularly relates to element-energy reinforced far-infrared refined molecular active cotton which is prepared from 100 parts of element-energy far-infrared mineral powder and 200-900 parts of polyurethane foaming raw materials, the element-energy far-infrared mineral powder comprises 30-40 parts of aluminum oxide, 25-35 parts of zinc oxide, 10-20 parts of silicon oxide and 4.0-8.0 parts of titanium oxide, and the element-energy far-infrared mineral powder is prepared from 100 parts of element-energy far-infrared mineral powder and 200-900 parts of polyurethane foaming raw materials. 10 to 14 parts of zirconium oxide and 1.5 to 2.5 parts of platinum. The technical problems that existing far infrared cotton obviously releases negative ions, contains high harmful radiation, is weak in far infrared energy and poor in application effect are solved, the active cotton has the advantages of being wide in emitted far infrared ray amplitude, high in strength and good in durability, blood circulation can be effectively improved, the whole tissue cell activity can be activated, and the health care effect is achieved. The repairing capability of autologous tissues is enhanced, and the problems of sleep obstruction and related soreness can be improved.

The application discloses a self-adapting valve skirt and a preparation method thereof, and particularly relates to the technical field of valves. The self-adapting valve skirt comprises an upper semi-permeable membrane, a lower semi-permeable membrane, a water-soluble adhesive and inorganic salt; the upper semi-permeable membrane and the lower semi-permeable membrane are sealed to form a membrane bag for embedding the water-soluble adhesive and the inorganic salt; and the outer sides of the upper semi-permeable membrane and the lower semi-permeable membrane are coated with a degradable coating layer for sealing pores. The self-adapting valve skirt has the self-adapting property of liquid, can well fill the gap between the valve and autologous tissue, and the free flow of liquid will not generate pressure on the contacted part, thereby affecting the conduction block.

A system and method for harvesting autologous tissue, mincing it into fragments that are visible and measurable when filtered, and delivering a portion of the tissue back into the patient without the need to directly touch the tissue. During the same surgical procedure, the tissue can be mixed with a biocompatible agent before introduction into the repair site.

The invention discloses a shaping method for filling depressed static lines with an autologous gel-state extract, and particularly relates to the technical field of medical cosmetology. The reshaping method comprises the following steps: cutting a small opening at one end of a wrinkle at a sunken part of skin, then putting a gel-state substance containing receptor venous blood into a subcutaneous gap of the opening, then taking the receptor venous blood again for extraction, injecting the obtained liquid extraction product into the gel-state substance containing the receptor venous blood, and finally performing reshaping on the gel-state substance containing the receptor venous blood to obtain the reshaping product containing the receptor venous blood. And after the volume is expanded until the concave part is raised, finishing the shaping of the concave static lines. According to the invention, the autologous tissue is used as a filler, so that no rejection reaction occurs in the subsequent treatment process; blood of a receptor is used as a raw material, so that the problem of vascular embolism is avoided, and serious negative effects such as skin necrosis and blinding are avoided; in addition, the reshaping method studied by the invention does not have the flow problem after filling the subcutaneous space, and the reshaping method is safer and more reliable.

The invention discloses a self-adaptive valve skirt and a preparation method thereof, and particularly relates to the technical field of valves. The self-adaptive valve skirt comprises an upper-layer semi-permeable membrane, a lower-layer semi-permeable membrane, a water-soluble adhesive and inorganic salt, the upper-layer semi-permeable membrane and the lower-layer semi-permeable membrane are sealed to form a membrane bag for embedding a water-soluble adhesive and inorganic salt; the outer sides of the upper-layer semi-permeable membrane and the lower-layer semi-permeable membrane are coated with degradable coatings for sealing pores. The self-adaptive valve skirt has the self-adaptability of liquid, a gap between the valve and autologous tissue is well filled, and free flowing of the liquid does not generate pressure on a contact part, so that conduction block is not influenced.